Download Advanced Issue Resolution in Safety Pharmacology Ebook PDF

Advanced Issue Resolution in Safety Pharmacology

Advanced Issue Resolution in Safety Pharmacology
A Book

by Mary Jeanne Kallman,Michael Pugsley

  • Publisher : Academic Press
  • Release : 2018-09-05
  • Pages : 360
  • ISBN : 0128123346
  • Language : En, Es, Fr & De
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Advanced Issue Resolution in Safety Pharmacology not only discusses unique issues that may emerge during the development of new medicines, but also provides detailed insights on how to resolve them. The book employs a valuable strategy that integrates preclinical findings with the clinical resolution of those findings. In addition, it introduces key interdisciplinary topics in an accessible and systematic format. Edited and written by leaders in the field of safety pharmacology, this book considerably advances the discussion on issue resolution topics, thus raising them to the next level of importance by providing scientists with an indispensable resource on solving safety issues. Focuses on pharmacology issues that result during drug development and provides de-risking techniques and practical advice Covers a broad selection of topics, including specialized animal models, PBPK modeling, the use of high frequency EEG in problem-solving, drug-induced self-injury, abuse potential liability, biomarkers, imaging, and much more Focuses on the resolution of these issues in order to better address regulatory expectancies and develop safer, more effective drugs

Principles of Safety Pharmacology

Principles of Safety Pharmacology
A Book

by Michael K. Pugsley,Michael J Curtis

  • Publisher : Springer
  • Release : 2015-06-19
  • Pages : 481
  • ISBN : 366246943X
  • Language : En, Es, Fr & De
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This book illustrates, in a comprehensive manner, the most current areas of importance to Safety Pharmacology, a burgeoning unique pharmacological discipline with important ties to academia, industry and regulatory authorities. It provides readers with a definitive collection of topics containing essential information on the latest industry guidelines and overviews current and breakthrough topics in both functional and molecular pharmacology. An additional novelty of the book is that it constitutes academic, pharmaceutical and biotechnology perspectives for Safety Pharmacology issues. Each chapter is written by an expert in the area and includes not only a fundamental background regarding the topic but also detailed descriptions of currently accepted, validated models and methods as well as innovative methodologies used in drug discovery.

Advanced Delivery and Therapeutic Applications of RNAi

Advanced Delivery and Therapeutic Applications of RNAi
A Book

by Kun Cheng,Ram I. Mahato

  • Publisher : John Wiley & Sons
  • Release : 2013-04-19
  • Pages : 536
  • ISBN : 1118610733
  • Language : En, Es, Fr & De
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Commonly used by researchers to develop technologies for modifying and studying genetic process, RNA interference (RNAi) has many potential uses in medicine, biotechnology, and functional genomics. This book covers all essential aspects involved in the development of RNAi therapeutics, providing detailed guidance on the challenges and opportunities of bringing RNAi technologies from bench to clinic. It explores the design and mechanism of RNAi molecules, delivery strategies, and therapeutic applications in various diseases. Preclinical, regulatory, market, and intellectual aspects of RNAi technologies are also covered.

Stem Cells - From Drug to Drug Discovery

Stem Cells - From Drug to Drug Discovery
A Book

by Khawaja Husnain Haider

  • Publisher : Walter de Gruyter GmbH & Co KG
  • Release : 2017-03-20
  • Pages : 232
  • ISBN : 3110493764
  • Language : En, Es, Fr & De
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Stem cell based therapy is a 21st century approach of therapeutic intervention which epitomizes a shift from conventional symptomatic treatment strategy to addressing the root cause of the disease process. This is especially a hope for the patients suffering from diseases such as Alzheimer, diabetes, myocardial infarction and other diseases which have always been considered as incurable. Moreover, stem cells provide excellent in vitro disease models for drug development. This book is a compilation of the bench experience of experts from various research labs involved in the cutting edge area of research, describing the use of stem cells both as part of the combinatorial therapeutic intervention approach and as tools (disease model) during drug development.

Advanced Pharmacology for Prescribers

Advanced Pharmacology for Prescribers
A Book

by Brent Q. Luu, PharmD, BCPS, BCACP,Gerald Kayingo, PhD, PA-C,Virginia McCoy Hass, DNP, MSN, RN, FNP-C, PA-C

  • Publisher : Springer Publishing Company
  • Release : 2021-01-13
  • Pages : 848
  • ISBN : 0826195474
  • Language : En, Es, Fr & De
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Delivers the critical information primary care providers need to be thoroughly informed prescribers This unique resource—an evidence-based pharmacology text and reference for advanced practice students and clinicians—guides users in analyzing the pharmacological foundations of drug therapy and fosters the development of sound clinical judgment in determining the appropriate medication for every patient across the lifespan. Targeting the specific needs of APRN and PA students and clinicians, the text is a “bridge” between standard, lengthy pharmacology texts and quick pocket references that lack information regarding key pharmacotherapy principles. Featuring an applied therapeutic approach to major disorders and their pharmacologic treatment, the book examines how medications act on the body and visa versa, while teaching the rationale for using specific therapeutic agents or drug classes. Each chapter includes case studies that apply the concepts discussed, relevant diagnostic studies, applicable guidelines, genomics, and important lifespan considerations. Of special interest is a chapter on pharmacogenetics explaining the basic principles underlying our current understanding of genetic variations in response to pharmacotherapy and adverse drug reactions. Easily digestible chapters include objectives and review questions. Ancillary resources include an instructor manual with learning objectives, chapter summaries, and case studies; chapter PowerPoint slides; test bank; and image bank. Key Features: Delivers an applied, evidence-based foundation on the basic science underlying prescribing Targets the specific needs of APRN and PA students and professionals and related healthcare providers Provides clinical decision-making tools and principles to support sound prescribing judgment Focuses on synthesizing drugs to manage commonly occurring disorders Includes strategies for addressing the needs of specific populations throughout the lifespan Includes abundant case studies illuminating key concepts Includes a robust instructor manual with learning objectives, chapter summaries, and case studies; PowerPoint slides; test bank; and image bank. Purchase includes access to the eBook for use on most mobile devices or computers.

Resolution Pharmacology - Innovative Therapeutic Approaches Based on the Biology of Resolution to Control Chronic Diseases of Western Societies

Resolution Pharmacology - Innovative Therapeutic Approaches Based on the Biology of Resolution to Control Chronic Diseases of Western Societies
A Book

by Mauro Perretti,Trinidad Montero-Melendez,Lucy V. Norling

  • Publisher : Frontiers Media SA
  • Release : 2019-11-04
  • Pages : 329
  • ISBN : 2889630846
  • Language : En, Es, Fr & De
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In this eBook, we have grouped together 16 original contributions which have addressed the translational potential for therapeutics developed on the conceptual framework of the resolution of inflammation. The take home message of our effort, and the efforts of our colleagues who wrote these pieces, is that completely different drugs can be designed and modelled on the mediators and targets of resolution. By implementing this 180° shift in the way we plan the drug development programme (that is by focusing on agonists and/or promoting the actions of pro-resolution agonists) we can offer a fresh approach to the clinical management of chronic diseases that affect the modern society. With this series of articles we foresee the birth of Resolution Pharmacology. The 16 contributions presented herein confirm the broad relevance of pro-resolving physio-pharmacology with the description of pro-resolving mechanisms in distinct diseases, from atherosclerosis and heart infarct, to cystic fibrosis and diabetes. This testifies on one hand the fundamental role that inflammatory mechanisms play in virtually all pathological settings and, on the other hand, the great potential that a novel approach to anti-inflammatory therapy by exploiting resolution mediators and targets may have. Thus, while there is broad recognition that evidence-based interventions have transformed cardiovascular, inflammation and endocrine care, new therapies are still needed for growing numbers of patients with unmet needs. As an example, an estimated 17 million people world-wide die annually of cardiovascular diseases, particularly heart attacks and strokes. Cardiovascular diseases occur almost equally in men and women and are the leading cause of death and morbidity worldwide. It is estimated that only 1/1,000 compounds entering preclinical testing are then trialled in man and the actual cost of developing a new therapeutic into clinical practice has grown exponentially over the past two decades (estimated $1.2B). Over the last 20 years or more, scientists have appreciated the biology of the resolution of inflammation, which provides a new paradigm in our understanding of the inflammatory process with the appreciation of genetic, molecular and cellular mechanisms that are engaged to actively resolve inflammation. The ‘resolution of acute inflammation’ is enabled by counter-regulatory checkpoints to terminate the host reaction while at the same time promoting healing and repair. The potential of lipid mediators to enact pro-resolving effects in the context of cystic fibrosis is presented by Recchiuti et al., while Fredman reasons on the potential for these molecules in atherosclerosis. This resonates well with the contributions from Bäck and colleagues who have focused on pro-resolving receptors to offer vasculo-protection in intimal hyperplasia and more generally in cardiovascular disease. On the same vein is the scholar contribution of Leoni and Soehnlein who focus on heart disease, with Qin et al. presenting the latest findings on the effect of an Annexin A1-derived peptide in myocardial infarction. Hansen et al. and de Gaetano et al. bring in the complexity of diabetes and associated morbidity with a focus on specialised pro-resolving lipid mediators but also introducing the potential of dietary approaches. As the western diet favours disease, an omega-3 rich diet can lead to higher availability of lipid mediators to afford tissue protection if not reverting its pathological status. Docosahexaenoic acid and its bioactive derivatives are endowed with potent anti-nociceptive properties following bone fracture, as shown by Zhang et al. The broad relevance of the pharmacological approach reaches the skin with Resolvin D1 protecting against UV irradiation (Saito et al.). Reduced skin inflammation is also achieved with an Annexin A1 peptide that impacts on the outcome of heterologous transplantation (Lacerda et al.). Indeed, modulating the phenotype of immune cells can provide long lasting beneficial outcomes, as attained with CDK inhibitors (Cartwright et al.) and PI3K inhibitors in experimental gout (Galvao et al.). Such an effect is also achieved with a third group of pro-resolving therapeutics, the melanocortin receptor agonists, with important modulation of macrophage reactivity (Patruno et al.) with Spana et al., providing new pharmacology following selective activation of the MC1 receptor. Finally, Hopkin et al. discuss the potential for targeting immune cell trafficking as a way to control immune mediated diseases, bringing in not only pro-resolving mediator agonists, but also approaches to reduce chemo/cytokine gradients or modulating S1P and 11-beta hydroxysteroid dehydrogenase. Finally, we wish to highlight that this wealth of science has also bought to the forefront specific pro-resolving receptors (including FPR2/ALX, GPR32, ChemR23 and MC1), all G protein coupled receptors that are therefore amenable to pharmacological exploitation for drug discovery programmes. We see that not only agonists to the receptors can be developed, some of them modelled on the natural ligands (e.g. resolvins, lipoxins, Annexin A1-derived peptides or melanocortin peptides), but also that the creativity of this pharmacology can be attained through biased ligands and positive allosteric modulators. Deep knowledge of pro-resolving receptor biology and their cell-specific signalling can accelerate the generation of novel anti-inflammatory depicted on the resolution of inflammation. In conclusion, with this eBook, we propose time is ready to exploit the concepts of resolution and use its targets and mediators for the identification of better drugs to establish ‘Resolution Pharmacology’. We predict Resolution Pharmacology will represent an important innovation in the way common diseases will be treated in the next decades of this millennium.

Stem Cells

Stem Cells
Regenerative Pharmacology, Drug Discovery and Development

by G. Sitta Sittampalam,Timothy Allsopp,David E. Thurston,David Fox,David Rotella

  • Publisher : Unknown Publisher
  • Release : 2013-12-30
  • Pages : 400
  • ISBN : 9781849731737
  • Language : En, Es, Fr & De
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This book will focus on the principle non-therapeutic ('superior cell tools') applications of stem cell technology, but will also include the emerging field of soluble, regenerative medicines. The scope will be a broad, contemporary review of the current state of the art for stem cell utilities in the biopharmaceutical research sector, with emphasis on technology strengths, challenges to resolve and prospects for future development. It will provide cutting edge opinion from academic and industrial leaders in the sector. The book's objectives include an overview of the fundamental science and technology components that underpin the utilities, an in depth review of the strength of the technology using a representative biopharmaceutical pipeline and case studies covering key therapeutic/development areas (oncology, cardio-vascular, neuroscience, safety pharmacology) and prediction of advanced applications (disease modelling, regenerative medicine). The book goes beyond the renowned applications and via the inclusion of hot topics such as reprogramming and modelling of tissue function in vitro will conveniently set the scene for further consideration as these fields continue to evolve. The editors collectively have nearly 35 years experience in the biopharmaceutical sector, many spent on direct utilization of stem cells and current affiliations are balanced by this in deployment to cover both academic and industrial perspectives. As the industry expands, investments increase and new international entrants and applications into the sector appear, a book reviewing contemporary and anticipating future stem cell utilities will be in major demand as no single review article can adequately cover the whole sector.

Basic Pharmacology for Nurses - E-Book

Basic Pharmacology for Nurses - E-Book
A Book

by Michelle Willihnganz,Bruce D. Clayton

  • Publisher : Elsevier Health Sciences
  • Release : 2016-02-25
  • Pages : 848
  • ISBN : 0323376975
  • Language : En, Es, Fr & De
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Known for its accurate, up-to-date drug content and its practical application of the nursing process to drugs and disorders, Clayton and Willihnganz’s Basic Pharmacology for Nurses, 17th Edition prepares you for safe medication administration. Emphasizing the nurse’s role, clear guidelines cover safe drug handling, types of drugs used for disorders or to affect body systems, injection and enteral administration, and patient education. From a respected PharmD/Nursing author team, this full-color text also provides an excellent review for the pharmacology questions on the NCLEX® examination. Current, accurate content ensures that the most current drugs and treatment protocols are presented. Application of the nursing process includes general principles of nursing care for each disorder, along with nursing considerations for drug treatment plans. An emphasis on safe drug handling and administration includes High Alert and Do Not Confuse icons as well as Medication Safety Alert boxes. A focus on patient education and health promotion equips you for health teaching related to medications. NCLEX® preparation sections at the end of each chapter helps you get ready for pharmacology-related questions on the NCLEX examination. A study guide corresponds to the textbook and offers review questions and clinical scenarios to reinforce your understanding of nursing pharmacology. Available separately. UPDATED drug coverage includes the most recent FDA approvals, withdrawals, and therapeutic uses. UPDTED guidelines cover injection and enteral medication administration, with an emphasis on safe medication practice. UPDATED treatment protocols include specific conditions such as asthma, hyperlipidemia, heart failure, COPD, and cancer. NEW! Objectives and key terms are listed at the beginning of each chapter, making it easy to see chapter content at a glance.

Proceedings of 15th Euro-Global Summit on Toxicology and Applied Pharmacology 2018

Proceedings of 15th Euro-Global Summit on Toxicology and Applied Pharmacology 2018
Journal of Clinical Toxicology : Volume 8

by ConferenceSeries

  • Publisher : ConferenceSeries
  • Release : 2021
  • Pages : 131
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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July 02-04, 2018 Berlin, Germany Key topics : Toxicology, Clinical & Medical Toxicology, Food and Nutritional Toxicology, Environmental Toxicology, Industrial & Occupational Toxicology, Systems Toxicology, Immunotoxicology, Chemical Carcinogenesis, Methods for Toxicity Testing, Risk Assessment, Toxicity Testing Markets, Emerging Toxicology Concepts, Molecular and Biochemical Toxicology, Reproductive and Developmental Toxicology, Genetic Toxicology, Drug Toxicology, Product Development Toxicology, Pharmacology, Developmental Pharmacology, Applied Pharmacology,

Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2011 Edition

Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2011 Edition
A Book

by Anonim

  • Publisher : ScholarlyEditions
  • Release : 2012-01-09
  • Pages : 4229
  • ISBN : 1464963444
  • Language : En, Es, Fr & De
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Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Pharmacology, Pharmacy, Drug Research, and Drug Innovation. The editors have built Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Pharmacology, Pharmacy, Drug Research, and Drug Innovation in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Topics in Clinical Pharmacology and Therapeutics

Topics in Clinical Pharmacology and Therapeutics
A Book

by Robert F. Maronde

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 518
  • ISBN : 1461248647
  • Language : En, Es, Fr & De
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Dr. Maronde has performed a major service in bringing together a superb array of scholars and clinicians to discuss not only the basic principles in therapeutics and clinical pharmacology but also the application of those principles to a wide range of clinical problems. Inclusion of chapters on adverse drug reactions, drug overdose, nonmedical prescription drug use, physician prescribing patterns, and the pharmaceutical industry makes this a particularly valuable book for clinicians. It is increasingly important that clinicians be well grounded in the principles of pharmacodynamics and pharmacokinetics because more and more of our patients are aging and cannot be treated as young or middle-aged adults. Elderly patients are liable to either drug overdose or underdose if traditional dosage formulas are followed because of changes in drug metabolism, drug distribution within the body, drug excretion, or changes in receptor site sensitivity. Because the elderly often present with mUltiple chronic diseases and require a variety of medications, they are more prone to medication errors, drug-drug interactions, and adverse drug reactions. The inclusion of three excellent chapters relating to drug-drug interactions, adverse drug reactions, and drug overdose is most welcome and is a valuable addition to this outstanding text on therapeutics and clinical pharmacology. Adverse drug reactions present a potentially serious problem for any patient for whom drugs are prescribed and particularly for those who must take multiple prescriptions.

Advanced Perioperative Crisis Management

Advanced Perioperative Crisis Management
A Book

by Matthew D. McEvoy,Cory M. Furse

  • Publisher : Oxford University Press
  • Release : 2017-07-25
  • Pages : 352
  • ISBN : 0190226463
  • Language : En, Es, Fr & De
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Advanced Perioperative Crisis Management is a high-yield, clinically-relevant resource for understanding the epidemiology, pathophysiology, assessment, and management of a wide variety of perioperative emergencies. Three introductory chapters review a critical thinking approach to the unstable or pulseless patient, crisis resource management principles to improve team performance and the importance of cognitive aids in adhering to guidelines during perioperative crises. The remaining sections cover six major areas of patient instability: cardiac, pulmonary, neurologic, metabolic/endocrine, and toxin-related disorders, and shock states, as well as specific emergencies for obstetrical and pediatric patients. Each chapter opens with a clinical case, followed by a discussion of the relevant evidence. Case-based learning discussion questions, which can be used for self-assessment or in the classroom, round out each chapter. Advanced Perioperative Crisis Management is an ideal resource for trainees, clinicians, and nurses who work in the perioperative arena, from the operating room to the postoperative surgical ward.

Pharmacy Workforce Support Personnel

Pharmacy Workforce Support Personnel
A Book

by Shane P. Desselle ,Kenneth C. Hohmeier

  • Publisher : MDPI
  • Release : 2020-12-10
  • Pages : 196
  • ISBN : 3039365436
  • Language : En, Es, Fr & De
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This book provides research and commentary on pharmacy technicians. It demonstrates how the re-design of pharmacy workflow to incorporate more responsibilities for technicians will free up pharmacist time to provide direct patient care. It also highlights that doing so can be accomplished without compromising—and often even improving upon—patient safety. The book also sheds light on employer needs and on new paradigms in pharmacy technician certification, education, and training. However, it also demonstrates the need for improvements in this area, as well as improvements in pharmacy technician quality of work life, advancement opportunities, and wages. Taken together, the papers in this book demonstrate how the results of recent studies help pave the road for the continued evolution of pharmacy care and the optimal deployment of pharmacy workforce personnel.

Nutraceuticals

Nutraceuticals
Efficacy, Safety and Toxicity

by Ramesh C. Gupta,Rajiv Lall,Ajay Srivastava

  • Publisher : Academic Press
  • Release : 2021-01-27
  • Pages : 1396
  • ISBN : 0128212462
  • Language : En, Es, Fr & De
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Nutraceuticals: Efficacy, Safety and Toxicity, Second Edition, brings together everything that is currently known about nutraceuticals and their potential toxic effects. The book introduces readers to nutraceuticals, herbal medicines, Ayurvedic medicines, prebiotics, probiotics, adaptogens, and their uses and specific applications. This essential reference discusses the mechanism of action for the judicious use of these nutraceuticals and the best tools for their evaluation before detailing the safety and toxicity of nutraceuticals and interactions with other therapeutic drugs. Finally, and crucially, regulatory aspects from around the world are covered. Completely revised and updated, this updated edition provides toxicologists, pharmacologists, pharmaceutical scientists, and those interested in medicinal plants and natural products with a comprehensive overview of the most effective tools upon which to evaluate the safety and toxicity of nutraceuticals, prebiotics, probiotics and alternative medicines. Presents a completely revised and updated resource on the impact of nutraceuticals and various disease states such as diabetes and ophthalmic and dermal diseases Grants an overview of the current state-of-the-science of nutraceuticals, their use and applications, and known adverse effects Provides effective tools to evaluate the potential toxicity of any nutraceutical Includes details of regulatory issues as written by international experts

The Pharmacy Technician, 7e

The Pharmacy Technician, 7e
A Book

by Perspective Press

  • Publisher : Morton Publishing Company
  • Release : 2020-01-15
  • Pages : 688
  • ISBN : 1640432183
  • Language : En, Es, Fr & De
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Endorsed by the American Pharmacists Association (APhA), The Pharmacy Technician, 7e, is a valuable tool for pharmacy technician students. This applied, accessible book is a practical text for understanding the principles, career concepts, and pharmacy skills needed to be a successful pharmacy technician. It offers clear, concise information to help students learn the material and pass the national certification exams: the Pharmacy Technician Certification Exam (PTCE), and the Exam for Certification of Pharmacy Technicians (ExCPT). This book was designed to be accompanied by The Pharmacy Technician, Workbook & Certification Review, 7e, to help prepare for the certification exams. This textbook aligns with the Fifth Edition of the American Society of Health-System Pharmacists (ASHP) Model Curriculum for Pharmacy Technician Education and Training Programs and the 2020 content outline for the Pharmacy Technician Certification Examination (PTCE).

Pharmacology for the Primary Care Provider

Pharmacology for the Primary Care Provider
A Book

by Marilyn W. Edmunds,Maren Stewart Mayhew

  • Publisher : Mosby
  • Release : 2004
  • Pages : 872
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The only pharmacology resource specifically written by and for nurse practitioners, this new edition provides a greater emphasis on prototype drugs while retaining its comprehensive approach to the pharmacology content needed by the primary care provider. New features include prototype drug lists in the coverage of drug classes that receive expanded coverage, detailed patient teaching guidelines, expanded content in both the geriatric and pediatric chapters, a special icon identifying the Top 200 Drugs, and highlighted Clinical Alerts. Comprehensive coverage is provided of all drugs commonly prescribed and used in the primary care setting. Prototype drugs are presented first in each drug class, with expanded coverage of these agents. Clear explanations describe how each drug in a class differs from its prototype. Detailed information shows how to provide effective patient teaching, as well as how to gain patient compliance. Chapters focus on the practitioner's role in patient teaching, drug action, and drug therapy. Online Resources are provided at the end of each chapter. The Top 200 Drugs are described according to the number of U.S. prescriptions dispensed. Five new units improve the organization of material: Renal/Genitourinary Agents (Unit 8); Psychotropic Agents (Unit 11); Endocrine Agents (Unit 12); Female Reproductive Agents (Unit 13); and Health Promotion (Unit 15). New chapters examine over-the-counter medications, compliance and the therapeutic experiment, overview of the nervous system, substance abuse, treatment of common infections, weight management, and complementary and alternative treatments. Reorganized and redesigned format and headings are more consistent and easy to follow. Content has been expanded in the geriatric and pediatric "special populations" chapters (Ch. 6 and 7). More concise coverage of disease processes features clearer ties to the Mechanism of Action sections. 25 new figures have been added to the pathophysiology and Mechanisms of Action sections. A Table of Common Interactions is included on the inside of the back cover.

Understanding Pharmacology - E-Book

Understanding Pharmacology - E-Book
Essentials for Medication Safety

by M. Linda Workman,Linda A. LaCharity

  • Publisher : Elsevier Health Sciences
  • Release : 2015-10-29
  • Pages : 560
  • ISBN : 0323339212
  • Language : En, Es, Fr & De
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Pharmacology can be difficult. But with the right text, understanding drugs and how they work doesn’t have to be! Using easy-to-follow language and engaging learning tools — like Memory Joggers, Clinical Pitfalls, Do Not Confuse, and Drug Alerts — the second edition of Understanding Pharmacology: Essentials for Medication Safety helps readers really understand how drugs work. In addition to the popular critical thinking activities from the first edition, the second edition also includes more chapter review questions, updated content, and a new organization that centers on the different body systems. For students who have a limited background in the sciences and want complete preparation for licensure exams and clinical practice, there is no better choice than Understanding Pharmacology, 2nd Edition! Entire unit reviewing math, weights and measures, and dosage calculation minimizes readers’ anxiety and promotes medication safety. Clever, easy-to-recognize margin icons help visual learners remember essential side effects of drugs. Simplified heading structure replaces intimidating terminology (i.e. pharmacokinetics) with simplified language (How These Drugs Work) to increase understanding of concepts. Drug Alert!, Do-Not-Confuse, and Clinical Pitfall boxes highlight important tips for safe medication administration. Memory Jogger boxes help readers remember important drug information. Get Ready for Practice sections at the end of each chapter include key points, chapter review questions, and critical thinking activities to reinforce learning. 10th grade reading level uses straightforward, everyday language to really enhance readers’ understanding of pharmacology concepts. Incorporation of adult learning theory features both a simple to complex organization of material along with answers to why readers need to learn something. NEW! Body system organization helps readers better understand drugs that are specific to particular body systems. NEW! More chapter review questions have been added to the text. All review questions are now organized into one of two categories: Test Yourself on the Basics and Test Yourself on Advanced Concepts.

Interagency Coordination in Drug Research and Regulation: Testimony and exhibits (including subsequent correspondence) on specialized drugs and drug problems: 1) drugs for mental illness; 2) antibiotics; 3) drug testing; 4) neonatal pharmacology; and 5) communication on drug emergencies

Interagency Coordination in Drug Research and Regulation: Testimony and exhibits (including subsequent correspondence) on specialized drugs and drug problems: 1) drugs for mental illness; 2) antibiotics; 3) drug testing; 4) neonatal pharmacology; and 5) communication on drug emergencies
A Book

by United States. Congress. Senate. Committee on Government Operations

  • Publisher : Unknown Publisher
  • Release : 1964
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The Pharmacy Technician Workbook and Certification Review, 7e

The Pharmacy Technician Workbook and Certification Review, 7e
A Book

by Perspective Press

  • Publisher : Morton Publishing Company
  • Release : 2020-01-15
  • Pages : 304
  • ISBN : 1640432191
  • Language : En, Es, Fr & De
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The Pharmacy Technician Workbook and Certification Review, 7e, is a valuable tool to prepare for the national PCTE and ExCPT certification exams. It corresponds with The Pharmacy Technician, 7e textbook. This edition has been updated to align with the Fifth Edition of the American Society of Health-System Pharmacists (ASHP) Model Curriculum for Pharmacy Technician Education and Training Programs and the 2020 content outline for the Pharmacy Technician Certification Examination (PTCE).

Advanced Technologies for the Quality Control and Standardization of Plant Based Medicines

Advanced Technologies for the Quality Control and Standardization of Plant Based Medicines
A Book

by Jiang Xu,Caroline Howard

  • Publisher : Frontiers Media SA
  • Release : 2020-06-18
  • Pages : 239
  • ISBN : 2889637980
  • Language : En, Es, Fr & De
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Herbs and herbal products are of paramount importance for human health. To beable to guarantee safety and quality, standards and testing methods are needed.Pharmacopoeias contain quality control protocols setting the standards which arethen required by governments. The quality traits are many, including the intrinsicvariables of medicinal plant, e.g. the levels of the active compounds, and the absenceof possibly natural occurring toxic compounds. On the other hand, many qualitytraits are related to agricultural conditions and practices, or to the harvesting andpost-harvest processing. With so many variables, quality control of the end productbecomes extremely complex, time consuming and costly. To ensure the quality ofmedicinal plants for human consumption quality management -the use of “goodpractices” at each step, from seed to final product- becomes a crucial aspect. In general, quality control includes the inspection of the product’s identity, purity,and content, based on its physical, chemical or biological properties. To ensure thequality of herbal medications, criteria such as botanical quality, type of preparation,physical constants, adulteration, contaminants, chemical constituents, pesticidesresidues et al. should be examined. Meanwhile, authentication of herbs is neededto avoid possible adulteration or contaminating plants, even toxic herbs such asAristolochia species. Many of the methods are long standing, such as microscopy incombination with color reactions, but some 50 years ago chromatography developedas a major tool for both qualitative and quantitative analysis of herbal preparations.Nowadays, research is working on the improvement of these methods and on thedevelopment of novel tools. For instance, next generation sequencing and mass spectrometry imaging, areemerging as new technologies for the quality control of herbal medicines. Withthese technologies, quick testing of herbal products and of mixed herbal powderpreparations, including the testing for specific plant parts (botanical drugs), can beachieved. Also, novel chemical tools such as metabolomics and Near Infrared Red(NIR) spectroscopy are being developed as powerful tools to identify and to linkthese with activity by using chemometric tools such as multivariate analysis. Finally,progress of informatic tools such as machine learning helps to deal with the big datagenerated by sequencing or mass spectrometry. However, these new technologies,like all other new born technologies, should be tested and perfected for a broaderrange of products.