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Advances and Challenges in Pharmaceutical Technology

Advances and Challenges in Pharmaceutical Technology
Materials, Process Development and Drug Delivery Strategies

by Amit Kumar Nayak,Kunal Pal,Indranil Banerjee,Samarendra Maji,Upendranath Nanda

  • Publisher : Academic Press
  • Release : 2021-02-19
  • Pages : 568
  • ISBN : 0128203005
  • Language : En, Es, Fr & De
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Advances and Challenges in Pharmaceutical Technology: Materials, Process Development and Drug Delivery Strategies examines recent advancements in pharmaceutical technology. The book discusses common formulation strategies, including the use of tools for statistical formulation optimization, Quality by design (QbD), process analytical technology, and the uses of various pharmaceutical biomaterials, including natural polymers, synthetic polymers, modified natural polymers, bioceramics, and other bioinorganics. In addition, the book covers rapid advancements in the field by providing a thorough understanding of pharmaceutical processes, formulation developments, explorations, and exploitation of various pharmaceutical biomaterials to formulate pharmaceutical dosage forms. Provides extensive information and analysis on recent advancements in the field of pharmaceutical technology Includes contributions from global leaders and experts in academia, industry and regulatory agencies Uses high quality illustrations, flow charts and tables to explain concepts and text to readers, along with practical examples and research case studies

Advances and Challenges in Pharmaceutical Technology

Advances and Challenges in Pharmaceutical Technology
Materials, Process Development and Drug Delivery Strategies

by Amit Kumar Nayak,Kunal Pal,Indranil Banerjee,Samarendra Maji,Upendranath Nanda

  • Publisher : Academic Press
  • Release : 2021-03-05
  • Pages : 568
  • ISBN : 012820043X
  • Language : En, Es, Fr & De
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Advances and Challenges in Pharmaceutical Technology: Materials, Process Development and Drug Delivery Strategies examines recent advancements in pharmaceutical technology. The book discusses common formulation strategies, including the use of tools for statistical formulation optimization, Quality by design (QbD), process analytical technology, and the uses of various pharmaceutical biomaterials, including natural polymers, synthetic polymers, modified natural polymers, bioceramics, and other bioinorganics. In addition, the book covers rapid advancements in the field by providing a thorough understanding of pharmaceutical processes, formulation developments, explorations, and exploitation of various pharmaceutical biomaterials to formulate pharmaceutical dosage forms. Provides extensive information and analysis on recent advancements in the field of pharmaceutical technology Includes contributions from global leaders and experts in academia, industry and regulatory agencies Uses high quality illustrations, flow charts and tables to explain concepts and text to readers, along with practical examples and research case studies

Pulmonary Drug Delivery

Pulmonary Drug Delivery
Advances and Challenges

by Ali Nokhodchi,Gary P. Martin

  • Publisher : John Wiley & Sons
  • Release : 2015-08-03
  • Pages : 384
  • ISBN : 1118799542
  • Language : En, Es, Fr & De
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Drug therapy via inhalation route is at the cutting edge of modern drug delivery research. There has been significant progress on the understanding of drug therapy via inhalation products. However, there are still problems associated with their formulation design, including the interaction between the active pharmaceutical ingredient(s) (APIs), excipients and devices. This book seeks to cover some of the most pertinent issues and challenges of such formulation design associated with industrial production and desirable clinical outcome. The chapter topics have been selected with a view to integrating the factors that require consideration in the selection and design of device and formulation components which impact upon patient usability and clinical effectiveness. The challenges involved with the delivery of macromolecules by inhalation to both adult and pediatric patients are also covered. Written by leading international experts from both academia and industry, the book will help readers (formulation design scientists, researchers and post-graduate and specialized undergraduate students) develop a deep understanding of key aspects of inhalation formulations as well as detail ongoing challenges and advances associated with their development.

Biopolymers In Drug Delivery: Recent Advances and Challenges

Biopolymers In Drug Delivery: Recent Advances and Challenges
A Book

by Michael U. Adikwu,Charles O. Esimone

  • Publisher : Bentham Science Publishers
  • Release : 2010-05-13
  • Pages : 223
  • ISBN : 1608050785
  • Language : En, Es, Fr & De
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"This Ebook describes the applicability of diverse natural and synthetic biopolymers and their blends in drugs, vaccines and gene delivery. It would serve as a concise body of information on biopolymers for researchers, industries and students of pharmaceu"

Advances and Challenges in Nanomedicine

Advances and Challenges in Nanomedicine
A Book

by Susan Hua,Sherry Y. Wu

  • Publisher : Frontiers Media SA
  • Release : 2019-02-28
  • Pages : 155
  • ISBN : 2889457451
  • Language : En, Es, Fr & De
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Nanotechnology is a multidisciplinary field that is revolutionizing the way we detect and treat damage to the human body. Nanomedicine applies nanotechnology to highly specific medical interventions for the prevention, diagnosis, and treatment of diseases. They are increasingly being used to overcome biological barriers in the body to improve the way we deliver compounds to specific tissues and organs. In particular, nanomedicines have been shown to be beneficial for stabilizing therapeutic compounds, overcoming obstacles to cellular and tissue uptake, and improving biodistribution of compounds to target sites in vivo. Nanomedicines have demonstrated significant therapeutic advantages for a multitude of biomedical applications, however the clinical translation of these nanotechnology platforms has not progressed as quickly as the plethora of positive results would have suggested. Understanding the advances in nanomedicine to date and the challenges that still need to be overcome, will allow future research to improve on existing platforms and to address the current translational and regulatory limitations. This eBook “Advances and Challenges in Nanomedicine” has brought together experts in the fields of nanomedicine, nanotechnology, nanotoxicology, pharmaceutics, manufacturing, and translation to discuss the application of nanotechnology to drug delivery. This information is presented as original research, opinion, perspective, and review articles. The goal of this eBook is to generate collaborative discussion on the current status, general trends, challenges, strategies, and future direction of pharmaceutical nanotechnology, as well as highlight current and emerging nanoparticulate platforms with potential medical applications.

Genomic Advances and Challenges in Old and New World Camelids

Genomic Advances and Challenges in Old and New World Camelids
A Book

by Pamela Burger,Jane Collins Wheeler,Kylie Ann Munyard,Pablo Orozco-terWengel,Elena Ciani

  • Publisher : Frontiers Media SA
  • Release : 2020-09-11
  • Pages : 329
  • ISBN : 2889661393
  • Language : En, Es, Fr & De
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Voigt's Pharmaceutical Technology

Voigt's Pharmaceutical Technology
A Book

by Alfred Fahr

  • Publisher : John Wiley & Sons
  • Release : 2018-04-16
  • Pages : 888
  • ISBN : 1118972627
  • Language : En, Es, Fr & De
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A textbook which is both comprehensive and comprehensible and that offers easy but scientifically sound reading to both students and professionals Now in its 12th edition in its native German, Voigt's Pharmaceutical Technology is an interdisciplinary textbook covering the fundamental principles of pharmaceutical technology. Available for the first time in English, this edition is produced in full colour throughout, with a concise, clear structure developed after consultation with students, instructors and researchers. This book: Features clear chapter layouts and easily digestible content Presents novel trends, devices and processes Discusses classical and modern manufacturing processes Covers all formulation principles including tablets, ointments, capsules, nanosystems and biopharmaceutics Takes account of legal requirements for both qualitative and quantitative composition Addresses quality assurance considerations Uniquely relates contrasting international pharmacopeia from EU, US and Japan to formulation principles Includes examples and text boxes for quicker data assimilation Written for both students studying pharmacy and industry professionals in the field as well as toxicologists, biochemists, medical lab technicians, Voigt’s Pharmaceutical Technology is the essential resource for understanding the various aspects of pharmaceutical technology.

Microbes in Applied Research

Microbes in Applied Research
Current Advances and Challenges

by A Mendez-Vilas

  • Publisher : World Scientific
  • Release : 2012-06-21
  • Pages : 696
  • ISBN : 9814405051
  • Language : En, Es, Fr & De
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This book offers the latest scientific research on applied microbiology presented at the IV International Conference on Environmental, Industrial and Applied Microbiology (BioMicroWorld2011) held in Spain in 2011. A wide-ranging set of topics including agriculture, environmental, food, industrial and medical microbiology makes this book interesting not only for microbiologists, but also for anyone who likes to keep up with cutting-edge research in microbiology and microbial biotechnology. Readers will find a major collection of knowledge, approaches, methods and discussions on the latest advances and challenges in applied microbiology in a compilation of 136 chapters written by active researchers in the field from around the world. The topics covered in this single volume include biodegradation of pollutants, water, soil and plant microorganisms, biosurfactants, antimicrobial natural products, antimicrobial susceptibility, antimicrobial resistance, human pathogens, food microorganisms, fermentation, biotechnologically relevant enzymes and proteins, microbial physiology, metabolism and gene expression mainly, although many other subjects are also discussed. Sample Chapter(s) A microcosm study on the die-off response of the indicator bacteria, Enterococcus faecium and Enterococcus faecalis (267 KB) Contents:Agriculture, Soil, Environmental and Marine–Aquatic MicrobiologyFood MicrobiologyIndustrial Microbiology. Methods. Quantitative Models and BioinformaticsMedical and Pharmaceutical Microbiology. Antimicrobial Agents and ChemotherapyMicrobial Physiology, Metabolism and Gene ExpressionBiotechnologically Relevant Enzymes and Proteins Readership: Professionals, microbiologists, clinicians, (bio)chemists, physicists, and engineers. Keywords:Microorganisms;Applied Microbiology;Environmental Microbiology;Industrial Microbiology;Microbial Biotechnology;BioMicroWorld2011 Conference Proceedings Book;Mendez-VilasKey Features:The topics covered in this single volume include biodegradation of pollutants, water, soil and plant microorganisms, biosurfactants, antimicrobial natural products, antimicrobial susceptibility, antimicrobial resistance, human pathogens, food microorganisms, fermentation, biotechnologically relevant enzymes and proteins, microbial physiology, metabolism and gene expression mainly, although many other subjects are also discussed

Ocular Drug Delivery: Advances, Challenges and Applications

Ocular Drug Delivery: Advances, Challenges and Applications
A Book

by Richard T. Addo

  • Publisher : Springer
  • Release : 2016-11-16
  • Pages : 185
  • ISBN : 3319476912
  • Language : En, Es, Fr & De
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The eye is a computerized system that has been designed for self-defense, and these defense mechanisms create challenges in administration of medications to the eye. Therefore, ocular drug delivery has been a major challenge to drug delivery researchers. There are on-going studies, in search of treatment especially for the diseases affecting the posterior segment of the eye. This book gives and overview of the background of ocular drug delivery and is unique for pharmacists, medical practitioners, students and drug delivery researchers.

Computational Pharmaceutics

Computational Pharmaceutics
Application of Molecular Modeling in Drug Delivery

by Defang Ouyang,Sean C. Smith

  • Publisher : John Wiley & Sons
  • Release : 2015-05-18
  • Pages : 328
  • ISBN : 111857396X
  • Language : En, Es, Fr & De
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Molecular modeling techniques have been widely used in drug discovery fields for rational drug design and compound screening. Now these techniques are used to model or mimic the behavior of molecules, and help us study formulation at the molecular level. Computational pharmaceutics enables us to understand the mechanism of drug delivery, and to develop new drug delivery systems. The book discusses the modeling of different drug delivery systems, including cyclodextrins, solid dispersions, polymorphism prediction, dendrimer-based delivery systems, surfactant-based micelle, polymeric drug delivery systems, liposome, protein/peptide formulations, non-viral gene delivery systems, drug-protein binding, silica nanoparticles, carbon nanotube-based drug delivery systems, diamond nanoparticles and layered double hydroxides (LDHs) drug delivery systems. Although there are a number of existing books about rational drug design with molecular modeling techniques, these techniques still look mysterious and daunting for pharmaceutical scientists. This book fills the gap between pharmaceutics and molecular modeling, and presents a systematic and overall introduction to computational pharmaceutics. It covers all introductory, advanced and specialist levels. It provides a totally different perspective to pharmaceutical scientists, and will greatly facilitate the development of pharmaceutics. It also helps computational chemists to look for the important questions in the drug delivery field. This book is included in the Advances in Pharmaceutical Technology book series.

Nanotechnologies in Neuroscience and Neuroengineering

Nanotechnologies in Neuroscience and Neuroengineering
A Book

by Ioan Opris,Mikhail Lebedev,Ruxandra Vidu,Victor Manuel Pulgar,Marius Enachescu,Manuel Fernando Casanova

  • Publisher : Frontiers Media SA
  • Release : 2020-05-05
  • Pages : 329
  • ISBN : 2889636755
  • Language : En, Es, Fr & De
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Pulmonary Drug Delivery

Pulmonary Drug Delivery
Advances and Challenges

by Ali Nokhodchi,Gary P. Martin

  • Publisher : John Wiley & Sons
  • Release : 2015-06-01
  • Pages : 384
  • ISBN : 1118799526
  • Language : En, Es, Fr & De
GET BOOK

Drug therapy via inhalation route is at the cutting edge of modern drug delivery research. There has been significant progress on the understanding of drug therapy via inhalation products. However, there are still problems associated with their formulation design, including the interaction between the active pharmaceutical ingredient(s) (APIs), excipients and devices. This book seeks to cover some of the most pertinent issues and challenges of such formulation design associated with industrial production and desirable clinical outcome. The chapter topics have been selected with a view to integrating the factors that require consideration in the selection and design of device and formulation components which impact upon patient usability and clinical effectiveness. The challenges involved with the delivery of macromolecules by inhalation to both adult and pediatric patients are also covered. Written by leading international experts from both academia and industry, the book will help readers (formulation design scientists, researchers and post-graduate and specialized undergraduate students) develop a deep understanding of key aspects of inhalation formulations as well as detail ongoing challenges and advances associated with their development.

Microencapsulation

Microencapsulation
Processes, Technologies and Industrial Applications

by Fabien Salaün

  • Publisher : BoD – Books on Demand
  • Release : 2019-10-02
  • Pages : 140
  • ISBN : 1838818693
  • Language : En, Es, Fr & De
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This book is intended to provide an overview and review of the latest developments in microencapsulation processes and technologies for various fields of applications. The general theme and purpose are to provide the reader with a current and general overview of the existing microencapsulation systems and to emphasize various methods of preparation, characterization, evaluation, and potential applications in various fields such as medicine, food, agricultural, and composites. The book targets readers, including researchers in materials science processing and/or formulation and microencapsulation science, engineers in the area of microcapsule development, and students in colleges and universities.

Controlled Drug Delivery Systems

Controlled Drug Delivery Systems
A Book

by Emmanuel C. Opara

  • Publisher : CRC Press
  • Release : 2020-02-28
  • Pages : 351
  • ISBN : 0429584652
  • Language : En, Es, Fr & De
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This book will describe current research on drug delivery systems that encompass four broad categories, namely: routes of delivery, delivery vehicles, payload, and targeting strategies. Where appropriate delivery vehicles and relevant release of specific agents in any of these categories in clinical application will be discussed. All chapters will highlight the translational aspects of the various technologies discussed and will provide insights into the advantages of such delivery systems over current ones in clinical or research use. Each technology reviewed in this book will have significant potential to improve patients' lives by enhancing the therapeutic efficacy of drugs. This book: Discusses the various factors that mitigate effective oral insulin delivery and the current status of research efforts to overcome these barriers along with recent clinical projections Examines the advantages and disadvantages of each drug delivery system Examines the standard method of accomplishing controlled drug release through the incorporation of the drugs within polymeric biomaterials such as capsules and microcapsules as well as other vehicles such as liposomes Discusses various controlled drug delivery systems, including sustained release delivery systems and pulse or delayed release, e.g. to target different regions of the gastrointestinal tract. In view of these wide-ranging technological areas, and the up-to-date discussions of opportunities and challenges associated with these applications, the book should provide readers from technology, materials science, pharmacology and clinical disciplines with very valuable information.

Safety and Regulatory Issues of Nanoencapsulated Food Ingredients

Safety and Regulatory Issues of Nanoencapsulated Food Ingredients
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2021-07-03
  • Pages : 314
  • ISBN : 0128165189
  • Language : En, Es, Fr & De
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Safety and Regulatory Issues of Nanoencapsulated Food Ingredients, a volume in the Nanoencapsulation in the Food Industry series, discusses the safety and toxicity potential of food-relevant and edible nanostructures, along with legislation issued by different countries and organizations governing their safety. The book's chapters cover safety issues of nanocapsules in food matrices, their possible toxicity effects, and in vitro and in vivo assays which are explored to underline their impact. Authored by a team of global experts in the fields of nano and microencapsulation of food, nutraceutical and pharmaceutical ingredients, this title is of great value to those engaged in fields surrounding nanoencapsulation. Explores how to analyze the safety of nanoencapsulated bioactive ingredients Discusses the regulations governing the safety of nanoencapsulated ingredients in different countries Investigates what agencies and which governmental organizations are responsible for the safety of nanoencapsulated ingredients

AAAS Bulletin

AAAS Bulletin
A Book

by American Association for the Advancement of Science

  • Publisher : Unknown Publisher
  • Release : 1964-11
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Micro- and Nanotechnologies-Based Product Development

Micro- and Nanotechnologies-Based Product Development
A Book

by Neelesh Kumar Mehra,Arvind Gulbake

  • Publisher : CRC Press
  • Release : 2021-09-07
  • Pages : 326
  • ISBN : 1000421600
  • Language : En, Es, Fr & De
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This book provides comprehensive information of the nanotechnology-based pharmaceutical product development including a diverse range of arenas such as liposomes, nanoparticles, fullerenes, hydrogels, thermally responsive externally activated theranostics (TREAT), hydrogels, microspheres, micro- and nanoemulsions and carbon nanomaterials. It covers the micro- and nanotechnological aspects for pharmaceutical product development with the product development point of view and also covers the industrial aspects, novel technologies, stability studies, validation, safety and toxicity profiles, regulatory perspectives, scale-up technologies and fundamental concept in the development of products. Salient Features: Covers micro- and nanotechnology approaches with current trends with safety and efficacy in product development. Presents an overview of the recent progress of stability testing, reverse engineering, validation and regulatory perspectives as per regulatory requirements. Provides a comprehensive overview of the latest research related to micro- and nanotechnologies including designing, optimisation, validation and scale-up of micro- and nanotechnologies. Is edited by two well-known researchers by contribution of vivid chapters from renowned scientists across the globe in the field of pharmaceutical sciences. Dr. Neelesh Kumar Mehra is working as an Assistant Professor of Pharmaceutics & Biopharmaceutics at the Department of Pharmaceutics, National Institute of Pharmaceutical Education & Research (NIPER), Hyderabad, India. He received ‘TEAM AWARD’ for successful commercialisation of an ophthalmic suspension product. He has authored more than 60 peer-reviewed publications in highly reputed international journals and more than 10 book chapter contributions. He has filed patents on manufacturing process and composition to improved therapeutic efficacy for topical delivery. He guided PhD and MS students for their dissertations/research projects. He has received numerous outstanding awards including Young Scientist Award and Team Award for his research output. He recently published one edited book, ‘Dendrimers in Nanomedicine: Concept, Theory and Regulatory Perspectives’, in CRC Press. Currently, he is editing books on nano drug delivery-based products with Elsevier Pvt Ltd. He has rich research and teaching experience in the formulation and development of complex, innovative ophthalmic and injectable biopharmaceutical products including micro- and nanotechnologies for regulated market. Dr. Arvind Gulbake is working as an Assistant Professor at the Faculty of Pharmacy, School of Pharmaceutical & Population Health Informatics, at DIT University, Dehradun, India. He has authored more than 40 peer-reviewed publications in highly reputed international journals, four book chapters and a patent contribution. He has received outstanding awards including Young Scientist Award and BRG Travel Award for his research. He is an assistant editor for IJAP. He guided PhD and MS students for their dissertations/research projects. He has successfully completed extramural project funded by SERB, New Delhi, Government of India. He has more than 12 years of research and teaching experience in the formulation and development of nanopharmaceuticals.

Eye Proteins—Advances in Research and Application: 2012 Edition

Eye Proteins—Advances in Research and Application: 2012 Edition
ScholarlyBrief

by Anonim

  • Publisher : ScholarlyEditions
  • Release : 2012-12-26
  • Pages : 409
  • ISBN : 146499353X
  • Language : En, Es, Fr & De
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Eye Proteins—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Eye Proteins in a concise format. The editors have built Eye Proteins—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Eye Proteins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Eye Proteins—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Recent Advancement in Prodrugs

Recent Advancement in Prodrugs
A Book

by Kamal Shah,Durgesh Nandini Chauhan,Nagendra Singh Chauhan,Pradeep Mishra

  • Publisher : CRC Press
  • Release : 2020-05-13
  • Pages : 336
  • ISBN : 1000057992
  • Language : En, Es, Fr & De
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Recent Advancement in Prodrugs Drugs used as medicines have many limitations like low chemical stability, aqueous solubility, or oral absorption/bioavailability, rapid presystemic metabolism, toxicity, inadequate site specificity, or poor patient acceptance/compliance (unwanted adverse effects, unacceptable taste or odor, irritation or pain). Prodrugs design is an approach to overcome these limitations. Key features Covers recent advancements in development of prodrugs Presents balanced synthesis and applications of prodrug chemistry Discusses broad spectrum of prodrug categories and outlines industrial applications Reviews prodrugs in cancer nanomedicine, its therapy and treatment Elucidates mathematical models to study the kinetics of prodrugs This book covers recent advances in the design of prodrugs. It contains all the significant recent examples of prodrug chemistry developments and will aid academics and researchers seeking to generate new projects in the field.

Applications of Encapsulation and Controlled Release

Applications of Encapsulation and Controlled Release
A Book

by Munmaya K. Mishra

  • Publisher : CRC Press
  • Release : 2019-09-18
  • Pages : 474
  • ISBN : 1000576647
  • Language : En, Es, Fr & De
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The field of encapsulation, especially microencapsulation, is a rapidly growing area of research and product development. Applications of Encapsulation and Controlled Release offers a broad perspective on a variety of applications and processes, including, up-to-date research, figures, tables, illustrations, and references. Written at a level comprehensible to non-experts, it is a rich source of technical information and current practices in research and industry.