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Advances in Cell and Molecular Diagnostics

Advances in Cell and Molecular Diagnostics
A Book

by Pongali Raghavendra,Thammineni Pullaiah

  • Publisher : Academic Press
  • Release : 2018-01-10
  • Pages : 298
  • ISBN : 0128136804
  • Language : En, Es, Fr & De
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Advances in Cell and Molecular Diagnostics brings the scientific advances in the translation and validation of cellular and molecular discoveries in medicine into the clinical diagnostic setting. It enumerates the description and application of technological advances in the field of cellular and molecular diagnostic medicine, providing an overview of specialized fields, such as biomarker, genetic marker, screening, DNA-profiling, NGS, cytogenetics, transcriptome, cancer biomarkers, prostate specific antigen, and biomarker toxicologies. In addition, it presents novel discoveries and clinical pathologic correlations, including studies in oncology, infectious diseases, inherited diseases, predisposition to disease, and the description or polymorphisms linked to disease states. This book is a valuable resource for oncologists, practitioners and several members of the biomedical field who are interested in understanding how to apply cutting-edge technologies into diagnostics and healthcare. Encompasses the current scientific advances in the translation and validation of cellular and molecular discoveries into the clinical diagnostic setting Explains the application of cellular and molecular diagnostics methodologies in clinical trials Focuses on translating preclinical tests to the bedside in order to help readers apply the most recent technologies to healthcare

Exam Prep for: Advances in Cell and Molecular Diagnostics

Exam Prep for: Advances in Cell and Molecular Diagnostics
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2021
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Molecular Diagnostics

Molecular Diagnostics
Techniques and Applications for the Clinical Laboratory

by Wayne W. Grody,Robert M. Nakamura,Frederick L. Kiechle,Charles Strom

  • Publisher : Academic Press
  • Release : 2009-11-06
  • Pages : 736
  • ISBN : 9780080919041
  • Language : En, Es, Fr & De
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Advances in genomic and proteomic profiling of disease have transformed the field of molecular diagnostics, thus leading the way for a major revolution in clinical practice. While the range of tests for disease detection and staging is rapidly expanding, many physicians lack the knowledge required to determine which tests to order and how to interpret results. Molecular Diagnostics provides a complete guide to the use and interpretation of molecular testing in the clinical arena. No other available resource offers this emphasis, comprehensive scope, and practical utility in the clinical setting. Serves as the definitivereference for molecular pathologists worldwide Covers a variety of molecular techniques including next generation sequencing, tumor somatic cell genotyping, infectious and genetic disease tecting, and pharmacogenetics Discusses in the detail issues concerning quality assurance, regulation, ethics, and future directions for the science

List of Journals Indexed in Index Medicus

List of Journals Indexed in Index Medicus
A Book

by National Library of Medicine (U.S.)

  • Publisher : Unknown Publisher
  • Release : 2001
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Issues for 1977-1979 include also Special List journals being indexed in cooperation with other institutions. Citations from these journals appear in other MEDLARS bibliographies and in MEDLING, but not in Index medicus.

Advances in Molecular Pathology

Advances in Molecular Pathology
A Book

by Gregory J. Tsongalis

  • Publisher : Elsevier
  • Release : 2018-11-28
  • Pages : 329
  • ISBN : 9780323639651
  • Language : En, Es, Fr & De
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This inaugural issue of Advances in Molecular Pathology will provide a comprehensive review of the most current practices, trends, and developments in the field of Molecular Pathology. Publishing on an annual basis, the volume will be divided into 7 sections: Genetics, Hematopathology, Infectious Disease, Pharmacogenomics, Informatics, Solid tumors, and Identity/HLA. Led by Dr. Gregory Tsongalis of Dartmouth University, a team of experienced pathologists from institutions across the country oversee annual topic and expert author selection. Topics discussed in this volume include, but are not limited to: whole genome sequencing in critically ill children, bioinformatics in clinical genomic sequencing, comprehensive monitoring of patients with chronic myeloid leukemia, genetic biomarkers in the biology and clinical workup of chronic lymphocytic leukemia, metagenomics in infectious disease, point of care molecular testing, pharmacogenomics in oncology, clinical uses of panel testing vs. single gene testing, large scale data sharing initiatives in genomic oncology, clinical NGS assays for solid tumors emerging concepts in liquid biopsy the cell line and tissue misidentification problem, and cell line detective work.

Advances in Optical Imaging and Photon Migration

Advances in Optical Imaging and Photon Migration
From the Topical Meeting [sic] Advances in Optical Imaging and Photon Migration, March 8-11, 1998, Orlando, Florida

by James G. Fujimoto,Michael S. Patterson

  • Publisher : Optical Society of Amer
  • Release : 1998
  • Pages : 478
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Recent Advances in Cell Biology of Acute Leukemia

Recent Advances in Cell Biology of Acute Leukemia
Impact on Clinical Diagnosis and Therapy

by Wolf-Dieter Ludwig,Eckhard Thiel

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 407
  • ISBN : 3642848958
  • Language : En, Es, Fr & De
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The development of new techniques such as immuno phenotyping, cytogenetic investigations and, more recently, molecular studies has considerably increased our diagnostic repertoire and broadened our ideas about the biology of acute leukemias. While immunophenotyping with mono clonal antibodies has yielded increased diagnostic precision and made it possible to develop a highly reproducible classification of acute leukemias based on cell-biological features, further insights have been gained into the patho genetic mechanisms involved in leukemogenesis by means of cytogenetic detection of acquired structural chromosomal abnormalities. Analysis of the leukemia-associated chromo somal breakpoints using molecular techniques can now pinpoint many genomic sites essential for normal develop ment and maturation of hematopoietic cells but functionally disrupted in leukemic cells. The main goal of the international workshop that we held in Berlin with a select group of scientists and clinicians involved in leukemia research was to describe the state of the art and new developments in the immunologic, cytogenetic, and molecular characterization of acute leukemias and to discuss the clinical importance of cell biological features. After introductory survey lectures dealing with the immunological and molecular-biological characteristics of normal vs. malignant lymphatic and myeloid progenitor cells, the workshop centered on con tributions characterizing the immunophenotype and both numerical and structural chromosomal abnormalities in acute leukemias.

Advances in the Pathophysiology, Diagnosis, and Treatment of Sickle Cell Disease

Advances in the Pathophysiology, Diagnosis, and Treatment of Sickle Cell Disease
Proceedings of the Tenth Annual Postgraduate Conference on Sickle Cell Disease Held in Washington, DC, September 24-26, 1981

by Roland B. Scott

  • Publisher : Unknown Publisher
  • Release : 1982
  • Pages : 165
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Molecular Diagnostics in Cancer Patients

Molecular Diagnostics in Cancer Patients
A Book

by Kamla Kant Shukla,Praveen Sharma,Sanjeev Misra

  • Publisher : Springer
  • Release : 2019-03-15
  • Pages : 341
  • ISBN : 981135877X
  • Language : En, Es, Fr & De
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This book aims to bring together a broad variety of examples of the role of pharmacogenomics in current drug development, uncovering dynamic concentration-dependent drug responses on biological systems to understand pharmacodynamics responses in human cancer where genetic lesions serve as tumor markers and provide a basis for cancer diagnosis. The book describes methods and protocols applied in molecular diagnostics. It offers pathologists and researchers providing molecular diagnostic services an array of the most recent and readily accessible reference to compare methods and techniques. Highlights include the molecular diagnosis of genetic aberrations by quantitative polymerase reaction (qPCR), sequence-specific oligonucleotide arrays, next-generation sequencing (NGS), CGH arrays-and methodologies directed at the detection of epigenetic events, high-throughput nucleic acid and protein arrays, direct sequencing and FISH-based methodologies, currently used in the diagnosis of solid tumors. The book also includes an innovative line of treatment in relation to the molecular prognosis, diagnosis and pharmacogenomics in the actual practice of clinical findings at molecular levels. The book covers the applications of numerous genetic testing methodologies; in approximately the chronological order of discovery and high-throughput diagnosis using advanced genomic approaches to identify such genes, in the search for novel drug targets and/or key determinants of drug reactions. It also promotes a wider understanding of molecular diagnostics among physicians, medical students, and scientists in academics, industry and corporate world.

Current Advances in Breast Cancer Research: A Molecular Approach

Current Advances in Breast Cancer Research: A Molecular Approach
A Book

by Shankar Suman,Garima Suman,Sanjay Mishra

  • Publisher : Bentham Science Publishers
  • Release : 2020-04-30
  • Pages : 401
  • ISBN : 9811451427
  • Language : En, Es, Fr & De
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Breast cancer is a recognized disease around the world with varying patient outcomes based on the type of breast cancer, access to healthcare and other factors. Survival rates for breast cancer are significantly lower in metastatic cases than localized cases. Early diagnosis and effective treatments for the efficient management of breast cancer are now in demand , as they help to prolong patient life. There have been many breakthrough developments in the molecular biology of breast cancer research in recent times. Advancements in diagnostic techniques (imaging and biomarker detection) for breast cancer have improved the screening of the disease and have improved patient outcomes. Despite these enhancements, the disease is still lethal for patients and the search for a cure requires a complete understanding of the disease. Current Advances in Breast Cancer Research: A Molecular Approach presents a comprehensive overview of current basic and translational research on the subject. The 14 chapters of the book give emphasis to current knowledge about breast cancer, ongoing challenges, and innovative research findings by different research groups. Readers will find detailed information about breast cancer biology, genetics, clinical diagnostics and treatments. Additional information for advanced readers in life sciences, such as techniques relevant to genomics (including genetic fingerprinting), proteomics, metabolomics and medicine (such as imaging and molecular diagnostics) is also provided. The combination of both basic and advanced information makes this book a useful reference to the student and researcher, alike, seeking an understanding about breast cancer at a molecular level.

Principles of Molecular Diagnostics and Personalized Cancer Medicine

Principles of Molecular Diagnostics and Personalized Cancer Medicine
A Book

by Dongfeng Tan,Henry T. Lynch

  • Publisher : Lippincott Williams & Wilkins
  • Release : 2012-12-07
  • Pages : 992
  • ISBN : 1469820641
  • Language : En, Es, Fr & De
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The role of molecular genetics in the treatment of malignancy continues to grow at an astonishing rate. Today’s subspecialized multidisciplinary approach to oncology has incorporated advances in targeted molecular therapy, prognosis, risk assessment, and prevention—all based at least in part on molecular diagnostics and imaging. Inside this cutting-edge resource, readers will explore broad, comprehensive perspectives on the current trends in molecular diagnosis of cancer and personalized cancer medicine. Authoritative discussions share insights from noted experts in cancer research, clinical trials, molecular diagnostics, personalized therapy, bioinformatics, and federal regulations. From the basic mechanisms of carcinogenesis to the most advanced molecular screening, staging, and treatment technologies, readers will discover clear and straightforward discussions directly relevant to patient diagnosis and care.

Molecular Diagnostics of Human Cancer

Molecular Diagnostics of Human Cancer
A Book

by Mark Furth,Melvyn F. Greaves,Melvyn Greaves

  • Publisher : Cold Spring Harbor Laboratory Press
  • Release : 1989
  • Pages : 414
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Scientists and physicians share overlapping interests in fundamental cancer biology and in the potential clinical ramifications of specific mutations in cancer cells. In this volume, they present their ideas on the role of oncogenes and their protein products in human tumors, with emphasis on diagnostic applications. They also review the medical implications of discoveries concerning the genetic basis of neoplastic disease. Topics include nuclear oncogene proteins; growth factors and their receptors; activation of ras, src, and raf oncogenes; chromosomal rearrangements associated with oncogene activation; gene loss in human cancers; the identification and potential function of anti-oncogenes ; the genetic basis for the resistance of tumor cells to chemotherapeutic drugs; and DNA tumor virus oncogenes in some human cancers. Molecular Diagnosis of Human Cancer also includes technical advances, as well as data on the diagnostic and prognostic implications of particular oncogene alterations in a number of cancers, notably pediatric neuroblastoma, the myelogenous leukemias, and carcinomas of the colon, bladder, pancreas, and breast.

Recent Advances in Cellular and Molecular Biology

Recent Advances in Cellular and Molecular Biology
From the 1. World Congress of C.M.B., Paris, September 1-7, 1991

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1992
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Advances in Diagnostic and Surgical Arthroscopy of the Temporomandibular Joint

Advances in Diagnostic and Surgical Arthroscopy of the Temporomandibular Joint
A Book

by Glenn T. Clark,Bruce Sanders,Charles Bertolami

  • Publisher : W B Saunders Company
  • Release : 1993
  • Pages : 179
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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A comprehensive and scholarly presentation of the scientific and clinical issues surrounding the diagnostic and surgical uses of arthroscopy. Includes discussions on treatment effectiveness, various diagnostic issues, and in-depth discussion on technology and research. Written by expert authors and generously illustrated.

Molecular Diagnostics in the Detection of Neurodegenerative Disorders

Molecular Diagnostics in the Detection of Neurodegenerative Disorders

by Megha Agrawal,William C. Cho

  • Publisher : Frontiers Media SA
  • Release : 2017-07-04
  • Pages : 329
  • ISBN : 2889451941
  • Language : En, Es, Fr & De
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Neurodegeneration is characterized by the progressive loss of neural tissue that result in various neurodegeneration-initiated cerebral failures and complex diseases such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease. All these medical conditions are accompanied by the disruption of blood-brain barrier (BBB). The BBB is an interface, separating the brain from the circulatory system and protecting the central nervous system from potentially harmful chemicals while regulating transport of essential molecules and maintaining a stable environment. Owing to the inability of the neurons to regenerate on their own after neurodegeneration or severe damage to the neural tissue, neurodegenerative disorders do not have natural cures on their own. Neuroregeneration is a viable way to curb neurodegeneration. One of the current approaches is stem cell-based therapy that has been shown to be potentially helpful for the application of neuronal cell replacement for neuroregeneration. It is vital that the neurodegenerative disorder being detected at an early stage as it can provide a chance for treatment that may be helpful to prevent further progression of the fatal disease. Thus, research has focused on developing effective non-invasive diagnostic methods for early detection of these disorders. Molecular diagnostics can provide a powerful method to detect and diagnose various neurological disorders. Such diagnosis can enhance early detection, provide subsequent medical counsel based on medical pathway, as well as to gain better insight of neurogenesis and hopefully eventual cure of the neurodegenerative diseases. With research reports, reviews, mini-reviews and commentary, this research topic covers a wide range of areas in neurodegeneration research, including diagnosis and prognosis; regulating central nervous system; biomarkers and brain injury induced neurobehavioral outcomes among other timely reports on neurodegeneration.

Advances in Clinical Chemistry

Advances in Clinical Chemistry
A Book

by Gregory S. Makowski

  • Publisher : Gulf Professional Publishing
  • Release : 2005-12-12
  • Pages : 424
  • ISBN : 9780120103409
  • Language : En, Es, Fr & De
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Volume forty in the internationally acclaimed Advances in Clinical Chemistry, contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics ranging from basic biochemical exploration to cutting edge microarray technology. In keeping with the tradition of the series, this volume emphasizes novel laboratory advances with application not only to both clinical laboratory diagnostics, but as well as practical basic science studies. This volume of Advances in Clinical Chemistry is an indispensable resource and practical guide for twenty-first century practitioners of clinical chemistry, molecular diagnostics, pathology, and clinical laboratory sciences in general. *Addresses biomarkers in heart disease and breast cancer *Presents the latest advances in real-time PCR with regard to clinical laboratory diagnostics *Written by international leaders in the field of clinical chemistry

Molecular Diagnostics in Pathology

Molecular Diagnostics in Pathology
A Book

by Cecilia M. Fenoglio-Preiser,Cheryl L. Willman

  • Publisher : Unknown Publisher
  • Release : 1991
  • Pages : 379
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Polymerase chain reaction cytogenetics & molecular cytoge- netics/disease assoc. polymorphisms & genetic linkage anlys

Advances in Gene Technology

Advances in Gene Technology
Molecular Biology in the Conquest of Disease, February 7-11, 1998 : Proceedings of the 1998 Miami Nature Biotechnology Winter Symposium

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1998
  • Pages : 192
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Advances in Laser Science II

Advances in Laser Science II
A Book

by International Laser Science Conference (2 : 1986 : Seattle),Stanley C. Stwalley

  • Publisher : American Institute of Physics
  • Release : 1987
  • Pages : 737
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Archives of Pathology & Laboratory Medicine

Archives of Pathology & Laboratory Medicine
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2004
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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