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Alcohol and Its Biomarkers

Alcohol and Its Biomarkers
Clinical Aspects and Laboratory Determination

by Amitava Dasgupta

  • Publisher : Elsevier
  • Release : 2015-02-18
  • Pages : 312
  • ISBN : 0128004096
  • Language : En, Es, Fr & De
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Alcohol and Its Biomarkers: Clinical Aspects and Laboratory Determination is a concise guide to all currently known alcohol biomarkers, their clinical application, and the laboratory methods used to detect them. Pathologists can use this resource to understand the limitations and cost factors associated with each method for determining certain alcohol biomarkers. In addition, interferences in these determinations are discussed, so that clinicians can understand the causes of falsely elevated biomarkers and pathologists and laboratory scientists can potentially eliminate them. The book focuses on the analytical methods used to detect alcohol in blood and urine, the limitations of alcohol determination using enzymatic methods, and the differences between clinical and forensic alcohol measurement. Chapters also cover cutting-edge alcohol biomarkers for potential use. Focuses on the analytical methods used for detecting alcohol in blood and urine along with the pitfalls and limitations of alcohol determination using enzymatic methods Explains the difference between clinical and forensic alcohol measurement Includes a brief overview of the benefits of consuming alcohol in moderation and the hazards of heavy drinking

Critical Issues in Alcohol and Drugs of Abuse Testing

Critical Issues in Alcohol and Drugs of Abuse Testing
A Book

by Amitava Dasgupta

  • Publisher : Academic Press
  • Release : 2019-01-10
  • Pages : 560
  • ISBN : 0128156082
  • Language : En, Es, Fr & De
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Critical Issues in Alcohol and Drugs of Abuse Testing, Second Edition, addresses the general principles and technological advances for measuring drugs and alcohol, along with the pitfalls of drugs of abuse testing. Many designer drugs, for example, are not routinely tested in drugs of abuse panels and may go undetected in a drug test. This updated edition is a must-have for clinical pathologists, toxicologists, clinicians, and medical review officers and regulators, bridging the gap between technical and clinical information. Topics of note include the monitoring of pain management drugs, bath salts, spices (synthetic marijuana), designer drugs and date rape drugs, and more. Serves as a ready resource of information for alcohol and drug testing Ideal resource for making decisions related to the monitoring and interpretation of results Includes concise content for clinical laboratory scientists, toxicologists and clinicians

Research on the Neurobiology of Alcohol Use Disorders

Research on the Neurobiology of Alcohol Use Disorders
A Book

by Leo Sher

  • Publisher : Nova Publishers
  • Release : 2008
  • Pages : 372
  • ISBN : 9781604561975
  • Language : En, Es, Fr & De
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This book describes the neurobiological mechanisms of alcohol abuse and dependence including the role of serotonergeic, dopaminergic, noradrenergic, and hypothalamic-piturary adrenal systems in alcohol use disorders and the results of neuroimaging studies are presented. The neurobiology of comorbidity of alcohol use disorders with other psychiatric disorders are also discussed. Research on the neurobiology of alcohol abuse and dependence is very important. Therefore, this book will be of interest to biomedical researchers, physicians, and other clinicians, students, and anyone who is interested in the mechanisms of addictive disorders.

Biomarker

Biomarker
A Book

by Tapan Khan

  • Publisher : BoD – Books on Demand
  • Release : 2012-04-27
  • Pages : 404
  • ISBN : 9535105779
  • Language : En, Es, Fr & De
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Clinicians, scientists, and health care professionals use biomarkers or biological markers as a measure of a person’s present health condition or response to interventions. An ideal -biomarker should have the following criteria: (I) ability to detect fundamental features of the disease, (II) ability to differentiate from other closely related diseases, (III) ability to detect early stages and stages of progression, (IV) the method should be highly reliable, easy to perform and inexpensive, and (V) sample sources should be easily accessible from body. Most of the chapters in this book follow the basic principle of biomarkers.

Alcohol, Drugs, and Impaired Driving

Alcohol, Drugs, and Impaired Driving
Forensic Science and Law Enforcement Issues

by A. Wayne Jones,Jorg Gustav Morland,Ray H. Liu

  • Publisher : CRC Press
  • Release : 2020-06-15
  • Pages : 700
  • ISBN : 1000048640
  • Language : En, Es, Fr & De
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Alcohol, Drugs, and Impaired Driving addresses many theoretical and practical issues related to the role played by alcohol and other psychoactive drugs on driving performance, road-traffic safety, and public health. Several key forensic issues are involved in the enforcement of laws regulating driving under the influence of alcohol and/or other drugs, including analytical toxicology, pharmacology of drug action, as well as the relationships between dose taken, concentration levels in the body, and impairment of performance and behavior. Our knowledge of drunken driving is much more comprehensive than drugged driving, so a large part of this book is devoted to alcohol impairment, as well as impairment caused by use of drugs other than alcohol. For convenience, the book is divided into four main sections. The first section gives some historical background about measuring alcohol in blood and breath as evidence for the prosecution of traffic offenders. The important role of the Breathalyzer instrument in traffic-law enforcement, especially in Australia, Canada, and the USA is presented along with a biographical sketch of its inventor (Professor Robert F. Borkenstein of Indiana University) with focus on the man, his work and his impact. The second section discusses several issues related to forensic blood and breath-alcohol alcohol analysis as evidence for prosecution of traffic offenders. This includes how the results should be interpreted in relation to impairment and an evaluation of common defense challenges. Because most countries have adopted concentration per se laws, the main thrust of the prosecution case is the suspect’s measured blood- or breath-alcohol concentration. This legal framework necessitates that the analytical methods used are "fit for purpose" and are subjected to rigorous quality assurance procedures. The third section gives a broad overview of the current state of knowledge about driving under the influence of non-alcohol drugs in various countries. This includes adoption of zero-tolerance laws, concentration per se statutes, and clinical evidence of driver impairment based on field sobriety tests and drug recognition expert evidence. The fourth section deals with epidemiology, enforcement, and countermeasures aimed at reducing the threat of drunken and drugged driving. All articles have appeared previously in the international journal Forensic Science Review, but all are completely updated with current data, references, and the latest research on developments since the articles were published. This book contains a convenient collection of the best articles covering recommendations for blood and breath testing methods, public policy relating to such methods, and forensic and legal implications of the enforcement of measures to counter driving under the influence.

Assessing Alcohol Problems

Assessing Alcohol Problems
A Guide for Clinicians and Researchers

by John P. Allen,Veronica B. Wilson

  • Publisher : Unknown Publisher
  • Release : 2003
  • Pages : 671
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Evidence-Based Addiction Treatment

Evidence-Based Addiction Treatment
A Book

by Peter M. Miller

  • Publisher : Academic Press
  • Release : 2009-07-08
  • Pages : 488
  • ISBN : 9780080921907
  • Language : En, Es, Fr & De
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Evidence-Based Addiction Treatment provides a state-of-the-art compilation of assessment and treatment practices with proven effectiveness. A substantial body of evidence is presented to provide students, academics, and clinicians with specific science-based treatments that work. The book includes contributions by well-known researchers on addiction treatment and explicit case examples. Written at a level appropriate for a variety of audiences, research studies are discussed but highly sophisticated knowledge in research methodology is not required. Treatments that work Explicit case examples Contributions by well-known researchers on addiction treatment Simple ways to evaluate treatment effectiveness

The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder

The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder

by American Psychiatric Association

  • Publisher : American Psychiatric Pub
  • Release : 2018-01-11
  • Pages : 224
  • ISBN : 0890426821
  • Language : En, Es, Fr & De
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Alcohol use disorder (AUD) is a major public health problem in the United States. The estimated 12-month and lifetime prevalence values for AUD are 13.9% and 29.1%, respectively, with approximately half of individuals with lifetime AUD having a severe disorder. AUD and its sequelae also account for significant excess mortality and cost the United States more than $200 billion annually. Despite its high prevalence and numerous negative consequences, AUD remains undertreated. In fact, fewer than 1 in 10 individuals in the United States with a 12-month diagnosis of AUD receive any treatment. Nevertheless, effective and evidence-based interventions are available, and treatment is associated with reductions in the risk of relapse and AUD-associated mortality. The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder seeks to reduce these substantial psychosocial and public health consequences of AUD for millions of affected individuals. The guideline focuses specifically on evidence-based pharmacological treatments for AUD in outpatient settings and includes additional information on assessment and treatment planning, which are an integral part of using pharmacotherapy to treat AUD. In addition to reviewing the available evidence on the use of AUD pharmacotherapy, the guideline offers clear, concise, and actionable recommendation statements, each of which is given a rating that reflects the level of confidence that potential benefits of an intervention outweigh potential harms. The guideline provides guidance on implementing these recommendations into clinical practice, with the goal of improving quality of care and treatment outcomes of AUD.

The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes

The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes
Volume III: Metabolic and Peripheral Biomarkers

by Michael Ritsner

  • Publisher : Springer Science & Business Media
  • Release : 2009-04-21
  • Pages : 213
  • ISBN : 1402098383
  • Language : En, Es, Fr & De
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Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer's disease, epilepsy, alcoholism, substance abuse and others are some of the most debilitating illnesses worldwide characterized by the complexity of causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunities to understand the etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. The challenge now is to translate these advances into meaningful diagnostic and therapeutic advances. This book offers a broad synthesis of the current knowledge about diverse topics of the biomarker and endophenotype strategies in neuropsychiatry. The book is organized into four interconnected volumes: “Neuropsychological Endophenotypes and Biomarkers” (with overview of methodological issues of the biomarker and endophenotype approaches in neuropsychiatry and some technological advances), “Neuroanatomical and Neuroimaging Endophenotypes and Biomarkers”, “Metabolic and Peripheral Biomarkers” and “Molecular Genetic and Genomic Markers”. The contributors are internationally and nationally recognized researchers and experts from 16 countries. This four-volume handbook is intended for a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, endocrinologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, health care providers in the field of neurology and mental health interested in trends that have crystallized in the last decade, and trends that can be expected to further evolve in the coming years. It is hoped that this book will also be a useful resource for the teaching of psychiatry, neurology, psychology and mental health.

The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes

The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes
Volume IV: Molecular Genetic and Genomic Markers

by Michael S. Ritsner

  • Publisher : Springer Science & Business Media
  • Release : 2009-04-24
  • Pages : 231
  • ISBN : 9048122988
  • Language : En, Es, Fr & De
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Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer’s disease, epilepsy, alcoholism, substance abuse and others are one of the most debilitating illnesses worldwide characterizing by the complexity of the causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunity to understand the etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. The challenge now is to translate these advances into meaningful diagnostic and therapeutic advances. This book offers a broad synthesis of the current knowledge about diverse topics of the biomarker and endophenotype strategies in neuropsychiatry. The book is organized into four interconnected volumes: “Neuropsychological Endophenotypes and Biomarkers” (with overview of methodological issues of the biomarker and endophenotype approaches in neuropsychiatry and some technological advances), “Neuroanatomical and Neuroimaging Endophenotypes and Biomarkers”, “Metabolic and Peripheral Biomarkers” and “Molecular Genetic and Genomic Markers”. The contributors are internationally and nationally recognized researchers and experts from 16 countries. This four-volume handbook is intended for a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, endocrinologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, health care providers in the field of neurology and mental health interested in trends that have crystallized in the last decade, and trends that can be expected to further evolve in the coming years. It is hoped that this book will also be a useful resource for the teaching of psychiatry, neurology, psychology and mental health.

Mental Retardation: New Insights for the Healthcare Professional: 2013 Edition

Mental Retardation: New Insights for the Healthcare Professional: 2013 Edition
ScholarlyPaper

by Anonim

  • Publisher : ScholarlyEditions
  • Release : 2013-07-22
  • Pages : 44
  • ISBN : 1481666606
  • Language : En, Es, Fr & De
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Mental Retardation: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Additional Research in a compact format. The editors have built Mental Retardation: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Additional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Mental Retardation: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

The Brain as a Drug Target

The Brain as a Drug Target
A Book

by Shafiqur Rahman

  • Publisher : Academic Press
  • Release : 2011-02-22
  • Pages : 468
  • ISBN : 0123855071
  • Language : En, Es, Fr & De
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The brain is protected by the blood-brain barrier and this barrier prevents many drugs from entering the brain. This volume discusses various drug delivery and targeting strategies that are being developed to enhance the transport and distribution of drugs into the brain. * Discusses new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields

The Handbook of Biomarkers

The Handbook of Biomarkers
A Book

by Kewal K. Jain

  • Publisher : Springer Science & Business Media
  • Release : 2010-02-06
  • Pages : 492
  • ISBN : 1607616858
  • Language : En, Es, Fr & De
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Of the thousands of biomarkers that are currently being discovered, relatively few are being validated for further applications, and the potential of a biomarker can be quite difficult to evaluate. To aid in this imperative research, Dr. Kewal K. Jain’s Handbook of Biomarkers thoroughly describes many different types of biomarkers and their discovery using various "-omics" technologies, such as proteomics and metabolomics, along with the background information needed for the evaluation of biomarkers as well as the essential procedures for their validation and use in clinical trials. With biomarkers described first according to technologies and then according to various diseases, this detailed book features the key correlations between diseases and classifications of biomarkers, which provides the reader with a guide to sort out current and future biomarkers. Comprehensive and cutting-edge, The Handbook of Biomarkers serves as a vital guide to furthering our understanding of biomarkers, which, by facilitating the combination of therapeutics with diagnostics, promise to play an important role in the development of personalized medicine, one of the most important emerging trends in healthcare today.

Molecular Aspects of Alcohol and Nutrition

Molecular Aspects of Alcohol and Nutrition
A Volume in the Molecular Nutrition Series

by Vinood B. Patel

  • Publisher : Academic Press
  • Release : 2015-11-06
  • Pages : 400
  • ISBN : 0128010037
  • Language : En, Es, Fr & De
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Molecular Aspects of Alcohol and Nutrition is a valuable resource for nutrition researchers and nutritionists who study or treat alcohol-related diseases. Experts from across the field of alcohol research explain how alcohol disrupts normal fat, carbohydrate, and protein metabolic processes occurring in the liver as well as other parts of the body. The book discusses how this can lead to alcoholic liver disease (ALD) as well as contribute to the onset of Type 2 diabetes and the metabolic syndrome. It also explores how alcohol affects nutrient absorption in the gastrointestinal tract and can lead to anemia and reduced amounts of fat soluble vitamins. This book explores both the primary and secondary consequences of alcohol consumption. Chapters in the first section investigate the basic science of alcohol metabolism – focusing on how alcohol and its toxic metabolites disrupt and impair normal nutrient regulation at the molecular level. Further chapters explore how alcohol affects many extra-hepatic organs and tissues as well as the secondary consequences of alcohol consumption such as reduced levels of minerals like magnesium, calcium, and trace elements like zinc. Offers a valuable resource for nutrition researchers and nutritionists who study alcohol-related diseases and attempt to treat them through nutritional strategies Explores how alcohol and its toxic metabolite acetaldehyde disrupt and impair normal macro and micro nutrient regulation at the molecular level Investigates how alcohol affects and interferes with cell signaling, cell death pathways, calcium homeostasis leading to osteoporosis, oxygen balance, as well as the pathophysiology of alcohol consumption and abuse

Alcohol Use Disorders and the Lung

Alcohol Use Disorders and the Lung
A Clinical and Pathophysiological Approach

by David M. Guidot,Ashish J. Mehta

  • Publisher : Springer Science & Business Media
  • Release : 2013-10-19
  • Pages : 252
  • ISBN : 1461488338
  • Language : En, Es, Fr & De
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Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach is an excellent resource for clinicians who care for individuals affected by alcohol use disorders in diverse settings. Although alcohol abuse alone does not cause acute lung injury, it renders the lung susceptible to dysfunction in response to the inflammatory stresses of sepsis, trauma, and other clinical conditions recognized to cause acute lung injury. In parallel, these same pathophysiological effects of alcohol abuse significantly increase the risk of a wide range of serious lung infections. Many clinicians involved in the primary treatment of alcohol use disorders, such as addiction psychiatrists, will find this text of interest as it will expand their understanding of the health consequences of alcohol use disorders. In parallel, clinicians who specialize in pulmonary and/or critical care medicine will have a unique resource that provides a comprehensive review of the pathophysiology of alcohol-related lung disorders and insights into evolving therapeutic options in these vulnerable individuals. Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach fills a gap in the literature and presents the evolving clinical research that may soon lead to novel therapies that can improve lung health in individuals with alcohol use disorders and co-existing conditions such as HIV infection.

Psychological Assessment of Veterans

Psychological Assessment of Veterans
A Book

by Shane S. Bush

  • Publisher : Oxford University Press (UK)
  • Release : 2014-08-27
  • Pages : 551
  • ISBN : 0199985723
  • Language : En, Es, Fr & De
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Psychological assessment is practiced in wide-ranging settings to address the varied clinical and administrative needs of veteran populations. Such assessment blends record review, clinical interviews of the veteran and collateral sources of information, behavioral observations, and psychological testing. This book promotes the care and well-being of veterans by bringing together knowledgeable and experienced psychologists to discuss a range of psychological assessment methods and procedures. It aims to help patients and their families, healthcare providers, and concerned citizens gain an improved understanding of veterans' cognitive functioning, emotional states, personality traits, behavioral patterns, and daily functioning. The book begins with a history of the psychological assessment of veterans and investigates its efficacy in different settings, including outpatient mental health, long-term care, primary care, home-based primary care, and telemental health. Later chapters address assessment of a variety of disorders or presenting problems, including substance use disorders, psychotic disorders, mood disorders and suicidal thoughts and behavior, PTSD and other anxiety disorders, attention-deficit/hyperactivity disorder, dementia, pain and pain-related disorders, and polytrauma. The book concludes with important special considerations, including assessment of symptom and performance validity, assessment of homeless veterans and health-related quality of life, and ethical, legal, and professional issues. Psychological Assessment of Veterans provides an essential reference and guide for clinical psychologists, including those working in the subspecialties, and psychology trainees who work with veterans.

Neuroscience of Alcohol

Neuroscience of Alcohol
Mechanisms and Treatment

by Victor R. Preedy

  • Publisher : Academic Press
  • Release : 2019-03-19
  • Pages : 736
  • ISBN : 0128131268
  • Language : En, Es, Fr & De
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Neuroscience of Alcohol: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of alcohol addiction and its effects on the brain. Offering thorough coverage of all aspects of alcohol research, treatment and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of alcohol misuse. Alcohol is one of the world’s most common addictive substances, with about two billion individuals worldwide consuming it in one form or another and three million annual deaths that are associated with alcohol misuse. Alcohol alters a variety of neurological processes, from molecular biology, to cognition. Moreover, addiction to alcohol can lead to numerous other health concerns and damage virtually every organ system in the body, making diagnosis and treatment of individuals addicted to alcohol of critical importance. Integrates cutting-edge research on the pharmacological, cellular and molecular aspects of alcohol use, along with its effects on neurobiological function Discusses alcohol use as a component of dual-use and poly addictions Outlines numerous screening and treatment strategies for alcohol misuse Covers both the physical and psychological effects of alcohol use and withdrawals to provide a fully-formed view of alcohol dependency and its effects

Structured management, Symptoms, Health-related Quality of Life and Alcohol in Patients with Atrial Fibrillation

Structured management, Symptoms, Health-related Quality of Life and Alcohol in Patients with Atrial Fibrillation
A Book

by Neshro Barmano

  • Publisher : Linköping University Electronic Press
  • Release : 2019-04-17
  • Pages : 99
  • ISBN : 9176851028
  • Language : En, Es, Fr & De
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Atrial fibrillation (AF) is the most common cardiac arrhythmia, affecting at least 2.9 % of the Swedish population. Although AF is associated with increased risk of ischaemic stroke, there have been many reports on the underuse of oral anticoagulants (OAC) and non-adherence to guidelines in other areas as well. AF is also associated with disabling symptoms and decreased health-related quality of life (HRQoL), but some patients are asymptomatic. The reasons for the great variation of symptoms remain unclear. Furthermore, although research on AF has increased, studies have mainly focused on treatment, while studies on risk factors, such as alcohol consumption, have only recently gained attention. The aim of this thesis was to investigate whether structured care of patients with AF could improve guideline adherence and HRQoL compared to standard care, and to determine which factors affect symptoms and HRQoL prior to treatment with radiofrequency catheter ablation (RFA), as well as improvement after RFA. Furthermore, we aimed to examine the associations of alcohol consumption with cardiac biomarkers, the size of the left atrium (LA), and re-ablation. This thesis is based on two studies. In the ‘Structured Management and Coaching – Patients with Atrial Fibrillation’ (SMaC-PAF) study, 176 patients were recruited to the intervention group, receiving a structured follow-up programme, and 146 patients were recruited to the control group, receiving standard care. The two groups were compared in regard to adherence to guidelines and patient-reported outcome measures (PROMs) assessing symptoms and HRQoL. In the ‘Symptom burden, Metabolic profile, Ultrasound findings, Rhythm, neurohormonal activation, haemodynamics and health-related quality of life in patients with atrial Fibrillation’ (SMURF) study, 192 patients referred for their first RFA of AF were included. PROMs questionnaires were filled out, echocardiography was performed, and cardiac biomarkers were analysed. Alcohol consumption was assessed through interview and through analysis of ethyl glucuronide in hair (hEtG). AF recurrence and re-ablation within 12 months were examined. In the first study, after one year, 94% (n=112) and 74% (n=87) of patients with indication for OAC in the intervention and the control groups, respectively, actually received treatment with OAC (p <0.01). Both groups improved in anxiety and HRQoL scores over the year, but in the intervention group, arrhythmia-specific symptoms were less frequently experienced and the SF-36 scores were more similar to the norm population. In the second study, the most important predictors of arrhythmia-related symptoms and HRQoL prior to RFA were anxiety, depression and low-grade inflammation, while frequent AF attacks prior to RFA, freedom from AF recurrence after RFA, female gender, no enlarged LA, absence of diabetes, and the presence of heart failure were significant predictors of improvement in symptoms and HRQoL after RFA. Men with hEtG ≥7 pg/mg had higher levels of cardiac biomarkers, larger LA volumes and a higher re-ablation rate than men with hEtG <7 pg/mg, while no such findings were present in women. In conclusion, structured management was superior to standard care in patients with AF, emphasising the importance of structured care, adjusted to local requirements, in order to improve the care and well-being of patients with AF. Although the reasons for the great variety of symptoms in patients with AF still are not yet fully understood, it seems that psychological factors and inflammation play a role, and that improvement in symptoms and HRQoL after RFA is influenced by gender, diabetes, heart failure, LA size and the frequency of attacks before, as well as freedom from AF after, RFA. Finally, alcohol consumption corresponding to hEtG ≥7 pg/mg was associated with higher levels of cardiac biomarkers, larger LA size and a higher rate of re-ablation in men, implying that men with an hEtG-value ≥7 pg/mg have a higher risk for LA remodelling that could potentially lead to a deterioration of the AF situation.

Coders' Specialty Guide 2022: Pathology/ Laboratory (Volume I & II)

Coders' Specialty Guide 2022: Pathology/ Laboratory (Volume I & II)
A Book

by AAPC

  • Publisher : AAPC
  • Release : 2022-01-01
  • Pages : 1044
  • ISBN : 1646312821
  • Language : En, Es, Fr & De
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Conquer 2022 CPT® and HCPCS code changes for pathology and improve your reporting accuracy and productivity. Say goodbye to coding confusion, claim denials, and lost revenue with AAPC’s one-stop Coders’ Specialty Guide 2022: Pathology/ Laboratory. This vital resource, with its smartly designed quick-reference layout, gives you instant access to everything you need for each CPT® code, all intelligently organized on one page—lay terms, ICD-10 CrossRefs, CCI edits, modifier crosswalks, relative value units, Medicare fee essentials, helpful indicators, and coding tips. Defeat your pathology and laboratory coding challenges with these indispensable features: Pathology and Laboratory CPT® codes, including 2022 new and revised codes Official descriptors for Categories I-III Lay term description of how each procedure is performed in plain English Specialized advice on pathology and laboratory coding and billing by industry experts Fee schedule (physicians and hospitals) along with RVUs Detailed illustrations for numerous pathology and laboratory procedures CCI edits for procedures Coding indicators for global days, diagnostic tests, and more Appendix of terminology and definitions HCPCS codes with lay terms and expert tips to help you capture complete reimbursement ICD-10-CM-to-CPT® crosswalks to facilitate more accurate code searching Index with page numbers to simplify your code search Headers with code ranges on each page for easier navigation Illustrations with code captions to interpret procedures And much more! Say goodbye to claim denials and hello to impeccable reporting with the Coders’ Specialty Guide 2022: Pathology/ Laboratory. *CPT® is a registered trademark of the American Medical Association

Information Resources in Toxicology

Information Resources in Toxicology
Volume 1: Background, Resources, and Tools

by Steve Gilbert,Asish Mohapatra,Sol Bobst,Antoinette Hayes,Sara T. Humes

  • Publisher : Academic Press
  • Release : 2020-05-16
  • Pages : 1054
  • ISBN : 0128137258
  • Language : En, Es, Fr & De
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This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools. Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology’s presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field. The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children’s environmental health. Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources. Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles. Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals. Explores recent internet trends, web-based databases, and software tools in a section on the online environment. Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents. Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field.