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Alcohol and Its Biomarkers

Alcohol and Its Biomarkers
Clinical Aspects and Laboratory Determination

by Amitava Dasgupta

  • Publisher : Elsevier
  • Release : 2015-02-18
  • Pages : 312
  • ISBN : 0128004096
  • Language : En, Es, Fr & De
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Alcohol and Its Biomarkers: Clinical Aspects and Laboratory Determination is a concise guide to all currently known alcohol biomarkers, their clinical application, and the laboratory methods used to detect them. Pathologists can use this resource to understand the limitations and cost factors associated with each method for determining certain alcohol biomarkers. In addition, interferences in these determinations are discussed, so that clinicians can understand the causes of falsely elevated biomarkers and pathologists and laboratory scientists can potentially eliminate them. The book focuses on the analytical methods used to detect alcohol in blood and urine, the limitations of alcohol determination using enzymatic methods, and the differences between clinical and forensic alcohol measurement. Chapters also cover cutting-edge alcohol biomarkers for potential use. Focuses on the analytical methods used for detecting alcohol in blood and urine along with the pitfalls and limitations of alcohol determination using enzymatic methods Explains the difference between clinical and forensic alcohol measurement Includes a brief overview of the benefits of consuming alcohol in moderation and the hazards of heavy drinking

Alcohol Research & Health

Alcohol Research & Health
The Journal of the National Institute on Alcohol Abuse and Alcoholism

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2001
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Critical Issues in Alcohol and Drugs of Abuse Testing

Critical Issues in Alcohol and Drugs of Abuse Testing
A Book

by Amitava Dasgupta

  • Publisher : Academic Press
  • Release : 2019-01-10
  • Pages : 560
  • ISBN : 0128156082
  • Language : En, Es, Fr & De
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Critical Issues in Alcohol and Drugs of Abuse Testing, Second Edition, addresses the general principles and technological advances for measuring drugs and alcohol, along with the pitfalls of drugs of abuse testing. Many designer drugs, for example, are not routinely tested in drugs of abuse panels and may go undetected in a drug test. This updated edition is a must-have for clinical pathologists, toxicologists, clinicians, and medical review officers and regulators, bridging the gap between technical and clinical information. Topics of note include the monitoring of pain management drugs, bath salts, spices (synthetic marijuana), designer drugs and date rape drugs, and more. Serves as a ready resource of information for alcohol and drug testing Ideal resource for making decisions related to the monitoring and interpretation of results Includes concise content for clinical laboratory scientists, toxicologists and clinicians

Alcohol-related Susceptible Biomarkers of Esophageal, Stomach and Liver Cancers

Alcohol-related Susceptible Biomarkers of Esophageal, Stomach and Liver Cancers
A Book

by Nai-chieh Yuko You

  • Publisher : Unknown Publisher
  • Release : 2006
  • Pages : 284
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2000

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2000
Hearings Before a Subcommittee of the Committee on Appropriations, House of Representatives, One Hundred Sixth Congress, First Session

by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies

  • Publisher : Unknown Publisher
  • Release : 1999
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The Defense of the Criminal Offense

The Defense of the Criminal Offense
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2007
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The Science of Drinking

The Science of Drinking
How Alcohol Affects Your Body and Mind

by Amitava Dasgupta

  • Publisher : Rowman & Littlefield Publishers
  • Release : 2011-04-16
  • Pages : 280
  • ISBN : 1442204117
  • Language : En, Es, Fr & De
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Scientific research has clearly established that drinking in moderation has many health benefits, including maintaining a healthy heart. Yet, many people do not know that drinking red wine protects the heart more than white wine, while beer, margaritas, and hard liquor are less effective in providing such protection. And while alcoholism is a serious problem requiring medical and psychological treatment, for those who are not addicted, drinking alcohol is not necessarily a bad habit. The problem is to distinguish between drinking sensibly and drinking insensibly. Dasgupta clearly outlines what constitutes healthy drinking and its attendant health benefits, offers advice on how to drink responsibly, and provides insight into just how alcohol works on the brain and the body. After reading this book, readers will enjoy their next drink with a fuller and safer understanding of why they're enjoying it.

SAMHSA News

SAMHSA News
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2006
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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American Biotechnology Laboratory

American Biotechnology Laboratory
Buyer's guide edition

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The Effects of Soy Protein Isolate on Cancer Biomarkers in Men at High Risk of Prostate Cancer

The Effects of Soy Protein Isolate on Cancer Biomarkers in Men at High Risk of Prostate Cancer
Results from the Soycap Trial

by Jill Marie Hamilton-Reeves

  • Publisher : Unknown Publisher
  • Release : 2006
  • Pages : 426
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Evaluating Transdermal Alcohol Measuring Devices

Evaluating Transdermal Alcohol Measuring Devices
A Book

by Paul R. Marques

  • Publisher : Unknown Publisher
  • Release : 2007
  • Pages : 86
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Cancer Causes & Control

Cancer Causes & Control
CCC.

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2006
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Colorectal Cancer: Molecular Mechanisms, Premalignant State and Its Prevention

Colorectal Cancer: Molecular Mechanisms, Premalignant State and Its Prevention
A Book

by W. Schmiegel,J. Schölmerich

  • Publisher : Springer
  • Release : 1999-04-30
  • Pages : 282
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Colorectal cancer is one of the most common causes of tumour-associated death in Western countries, and its incidence has been increasing in recent decades. The most important determinant for the course of the disease is tumour stage at the time of diagnosis. The detection of molecular changes in tumour tissue and in benign adenomatous polyps has improved our knowledge of colorectal carcinogenesis. Diseases with a high risk for malignant transformation, as well as family predisposition as an independent risk factor, have been identified. Furthermore, dietary and environmental factors, together with the intake of aspirin and other NSAIDs, influence tumor development. This implies new ways of specific testing for early diagnosis and new prevention strategies based on endoscopy and drug therapy. The main topics of this book, the proceedings of the international Falk Symposium No. 109, held in Titisee, Germany, on October 14-15, 1998, are molecular mechanisms, premalignant state and prevention. State-of-the-art chapters deliver the latest scientific developments on every topic, followed by more detailed chapters on specific items.

Analysis of Biomarkers of Lipid Peroxidation Using Mass Spectrometry

Analysis of Biomarkers of Lipid Peroxidation Using Mass Spectrometry
Aldehydes and Peptide and Protein Conjugates of 4-hydroxy-2-nonenal

by Bernd Andreas Bruenner

  • Publisher : Unknown Publisher
  • Release : 1995
  • Pages : 246
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Peripheral Biological Markers in Alcoholism

Peripheral Biological Markers in Alcoholism
A Book

by Nela Pivac

  • Publisher : Nova Biomedical
  • Release : 2008
  • Pages : 93
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Alcoholism is a complicated disorder that is often characterised with refractoriness to treatment, chronic course, high comorbidity and frequently with aggressive and suicidal behaviour. The neurobiological basis of alcoholism is assumed to be associated with the altered functions of different neurotransmitter (opioid, GABA, dopamine or serotonin (5-hydroxytryptamine, 5-HT)) systems. The association between central serotonergic function and the development and maintenance of alcohol abuse and dependence is based on the preclinical and clinical data, which show decreased 5-HT function associated with alcohol abuse. Peripheral biochemical markers might be used to improve the understanding of the underlying neurobiology of alcoholism, but also for the screening, establishing the diagnosis, disease staging, prediction of the suicidal risk and prediction and monitoring of treatment. Since 5-HT synaptosomes in the central nervous system and platelets similarly store, release and metabolise 5-HT, blood platelets have been widely used as a limited peripheral model for the central serotonergic synaptosomes. Various 5-HT abnormalities are frequently found in alcoholism, and decreased plasma tryptophan levels, decreased but also unaltered concentration of platelet 5-HT, increased platelet 5-HT uptake, and decreased and unchanged platelet monoamine oxidase (MAO) activity in alcoholic subjects have been reported. Deficits in central 5-HT function in alcoholic subjects were also detected after a challenge tests with fenfluramine, m-clorophenylpiperasine, and 6-chloro-2-1-piperazinylpyrazine, which resulted in blunted prolactin and cortisol responses. Alcoholism is frequently associated with different comorbid psychiatric disorders (personality disorder, PTSD, anxious-depressive disorder, major depression, schizophrenia), and with nicotine addiction. Clinical diagnosis of alcoholism was made according to the DSM-IV criteria, using Structured clinical interview and CAGE. Different clinical symptoms were evaluated using Hamilton Rating Scale for Depression and Anxiety. Control group consisted of drug free healthy persons with no personal or family history of alcoholism, who did not consume any alcohol beverage 24 h prior to sampling. All subjects fulfilled the questionnaire regarding their smoking habits. Biomarkers studied were platelet 5-HT concentration, platelet MAO activity, and routine laboratory tests, determined using spectrofluorimetric and photometric methods. Since platelet 5-HT concentration and/or MAO activity are under influence of sex, psychotic or depressive symptoms, suicidal behaviour, smoking status, or different psychiatric comorbid diagnoses, the authors determined platelet 5-HT concentration and platelet MAO activity in the large groups of drug-free alcoholics who were admitted into hospital due to the withdrawal syndrome related to alcohol dependency, and compared these values in the sex-matched healthy controls. They also investigated whether sex, smoking status, the presence of psychotic or depressive symptoms, suicidal behavior, number of cigarettes smoked per day, or different psychiatric comorbid diagnoses, would affect platelet 5-HT and MAO in male and female alcoholic patients. The data suggest that biological markers are very important research tool in alcoholism, since they can be used to determine the baseline characteristics of the alcoholic groups, to predict a suicidal risk in alcoholism, to predict efficacy in alcoholism treatment trials, to predict therapeutic response to medications in alcoholism, to measure alcohol consumption, and to be used in forensic toxicology.

Biomarkers of Human Exposure to Pesticides

Biomarkers of Human Exposure to Pesticides
Developed from a Symposium Sponsored by the Division of Agrochemicals at the 204th National Meeting of the American Chemical Society, Washington, DC, August 23-28, 1992

by Mahmoud A. Saleh,Jerry N. Blancato,Charles H. Nauman,American Chemical Society. Division of Agrochemicals,American Chemical Society. Meeting

  • Publisher : Amer Chemical Society
  • Release : 1994
  • Pages : 326
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Explores the role of biomarker data in evaluating the impact of human environmental and occupational exposure to pesticides. Focuses on two types of biomarkers: residue analysis of parent compounds or metabolites and end points representing interactions between xenobiotic and endogenous components. Characterizes the molecular basis of various biomarker methods and examines structure-activity relationships. Surveys biomarker measurement methods currently in use and examines methods for biomarker data analysis and applications of these methods to risk assessment.

Comprehensive Handbook of Alcohol Related Pathology

Comprehensive Handbook of Alcohol Related Pathology
A Book

by Victor R. Preedy,Ronald Ross Watson

  • Publisher : Academic Press
  • Release : 2005
  • Pages : 1670
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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This comprehensive handbook is a "one-stop-shop" for all researchers involved in the field of alcohol-related harm at the whole body or cellular level. Over 100 chapters provide abundant information of a wide range of topics that extend from the evolutionary aspects of alcohol consumption and the prevalence of alcohol misuse to programmed cell death. Each chapter is highly illustrated with tables and figures making this a valuable reference for students, clinicians and researchers alike.*Over 100 chapters conveniently divided into 3 sections*Represents a 'one-stop-shop' of information with suitable indexing of the various pathways and processes*Each chapter is highly illustrated with tables as well as figures

Research Update

Research Update
Alcohol Use and Pregnancy : an Important Canadian Public Health and Social Issue

by Colleen Anne Dell,Gary Roberts,Public Health Agency of Canada

  • Publisher : Unknown Publisher
  • Release : 2006
  • Pages : 101
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Alcohol, Drugs of Abuse and Immunomodulation

Alcohol, Drugs of Abuse and Immunomodulation
Proceedings of the 2nd International Conference on Alcohol, Drugs of Abuse and Immunomodulation (AIDS) Held in Arizona, USA, on 9-13 September 1992

by Ronald Ross Watson

  • Publisher : Pergamon
  • Release : 1993
  • Pages : 701
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The studies presented in this symposium volume investigate the mechanisms of the immune dysfunction due to alcohol, heroin, and cocaine use, and attempt to elucidate what their ultimate effects are on AIDS, cancer growth and infectious disease.

Inside Smithsonian Research

Inside Smithsonian Research
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2007
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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