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Bioresponsive Polymers

Bioresponsive Polymers
Design and Application in Drug Delivery

by Deepa H. Patel

  • Publisher : CRC Press
  • Release : 2020-10-09
  • Pages : 246
  • ISBN : 1000517594
  • Language : En, Es, Fr & De
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This volume, Bioresponsive Polymers: Design and Application in Drug Delivery, focuses on recent advancements in bioresponsive polymers and their design, characterization, and applications in varied fields, such as drug delivery and gene delivery. It looks at several carriers for drug delivery and biological molecules using different bioresponsive polymers. To address the many difficulties in existing dosage forms, this book provides information on recent developments to overcome drawbacks of conventional forms of the drug delivery. The chapters cover most areas of bioresponsive polymers, starting with a basic introduction to bioresponsive polymers, followed by chapters on design, characterization, and mechanism of bioresponsive polymers; and applications of drug and gene delivery using bioresponsive polymers via oral, topical, nasal, ocular, and parenteral methods. The book also reviews recent advancements in bioresponsive polymers and advanced applications, such as engineering particulate moieties, biomedical applications, hydrogels as emerging therapy, and electrochemical responses, bioresponsive nanoparticles, and bioresponsive hydrogels.

Functional Polymers for Nanomedicine

Functional Polymers for Nanomedicine
A Book

by Youqing Shen

  • Publisher : Royal Society of Chemistry
  • Release : 2013
  • Pages : 318
  • ISBN : 1849736200
  • Language : En, Es, Fr & De
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Interest in the application of nanotechnology to medicine has surged in recent years and could transform the way we diagnose, treat and prevent diseases such as cancer. However, the clinical success of nanomedicine is limited because of problems with toxicity and therapeutic efficacy. To overcome this it is essential to produce new nanosystems with specific functions, which can be achieved by designing new polymers with particular properties that can be used for nanomedicine. Functional Polymers for Nanomedicine provides a complete overview of the different strategies for designing polymers for nanomedicine applications. The first part of the book looks at the current problems and direction in nanomedicine including a review of current design and targeting of nanocarriers. The second part explores the design of polymers with different functions including hyperbranched polymers, polymersomes, polysaccharides, polymeric micelles and zwitterionic polymers and their applications in gene therapy and drug delivery. This timely book is edited by a leading scientist in nanomedicine and provides a suitable introduction and reference source for advanced undergraduates, postgraduates and academic and industrial researchers in polymer science, nanotechnology and pharmacy interested in materials for medical applications.

Smart Polymers and their Applications

Smart Polymers and their Applications
A Book

by Maria Rosa Aguilar,Julio San Román

  • Publisher : Elsevier
  • Release : 2014-02-19
  • Pages : 584
  • ISBN : 0857097024
  • Language : En, Es, Fr & De
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Smart polymers are polymers that respond to different stimuli or changes in the environment. Smart Polymers and their Applications reviews the types, synthesis, properties, and applications of smart polymers. Chapters in part one focus on types of polymers, including temperature-, pH-, photo-, and enzyme-responsive polymers. Shape memory polymers, smart polymer hydrogels, and self-healing polymer systems are also explored. Part two highlights applications of smart polymers, including smart instructive polymer substrates for tissue engineering; smart polymer nanocarriers for drug delivery; the use of smart polymers in medical devices for minimally invasive surgery, diagnosis, and other applications; and smart polymers for bioseparation and other biotechnology applications. Further chapters discuss the use of smart polymers for textile and packaging applications, and for optical data storage. Smart Polymers and their Applications is a technical resource for chemists, chemical engineers, mechanical engineers, and other professionals in the polymer industry; manufacturers in such sectors as medical, automotive, and aerospace engineering; and academic researchers in polymer science. Reviews the different types of smart polymer, discussing their properties, structure, design, and characterization Reviews applications of smart polymers in such areas as biomedical engineering, textiles, and food packaging

High Performance Functional Bio-based Polymers for Skin-contact Products

High Performance Functional Bio-based Polymers for Skin-contact Products
A Book

by Maria Beatrice Coltelli,Serena Danti

  • Publisher : MDPI
  • Release : 2021-01-14
  • Pages : 224
  • ISBN : 3039438611
  • Language : En, Es, Fr & De
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Beauty masks, diapers, wound dressings, wipes, protective clothes and biomedical products: all these high-value and/or large-volume products must be highly compatible with human skin and they should have specific functional properties, such as anti-microbial, anti-inflammatory and anti-oxidant properties. They are currently partially or totally produced using fossil-based sources, with evident issues linked to their end of life, as their waste generates an increasing environmental concern. On the contrary, biopolymers and active biomolecules from biobased sources could be used to produce new materials that are highly compatible with the skin and also biodegradable. The final products can be obtained by exploiting safe and smart nanotechnologies such as the extrusion of bionanocomposites and electrospinning/electrospray, as well as innovative surface modification and control methodologies. For all these reasons, recently, many researchers, such as those involved in the European POLYBIOSKIN project activities, have been working in the field of biomaterials with anti-microbial, anti-inflammatory and anti-oxidant properties, as well as biobased materials which are renewable and biodegradable. The present book gathered research and review papers dedicated to materials and technologies for high-performance products where the attention paid to health and environmental impact is efficiently integrated, considering both the skin-compatibility of the selected materials and their source/end of life.

Switchable and Responsive Surfaces and Materials for Biomedical Applications

Switchable and Responsive Surfaces and Materials for Biomedical Applications
A Book

by Johnathan Zhang

  • Publisher : Elsevier
  • Release : 2014-12-11
  • Pages : 324
  • ISBN : 0857097172
  • Language : En, Es, Fr & De
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Surface modification of biomaterials can ultimately determine whether a material is accepted or rejected from the human body, and a responsive surface can further make the material "smart" and "intelligent". Switchable and Responsive Surfaces and Materials for Biomedical Applications outlines synthetic and biological materials that are responsive under different stimuli, their surface design and modification techniques, and applicability in regenerative medicine/tissue engineering, drug delivery, medical devices, and biomedical diagnostics. Part one provides a detailed overview of switchable and responsive materials and surfaces, exploring thermo-responsive polymers, environmentally responsive polyelectrolytes and zwitterionic polymers, as well as peptide-based and photonic sensitive switchable materials. Further chapters include a detailed overview of the preparation and analysis of switchable polymer brushes and copolymers for biomedical application. Part two explores the biological interactions and biomedical applications of switchable surfaces, where expert analysis is provided on the interaction of switchable surfaces with proteins and cells. The interaction of stimuli-sensitive polymers for tissue engineering and drug delivery with biosurfaces is critiqued, whilst the editor provides a skillful study into the application of responsive polymers in implantable medical devices and biosensors. A comprehensive overview of switchable and responsive materials and surfaces Includes in depth analysis of thermo-responsive polymers, photonic sensitive materials and peptide-based surfaces Detailed exploration of biological interactions of responsive and switchable surfaces, covering stimuli-sensitive polymers for drug delivery, surfaces with proteins/cells and application of polymers in medical devices

Engineering Drug Delivery Systems

Engineering Drug Delivery Systems
A Book

by Ali Seyfoddin,Seyedehsara Masoomi Dezfooli,Carol Ann Greene

  • Publisher : Woodhead Publishing
  • Release : 2019-11-15
  • Pages : 250
  • ISBN : 0081025491
  • Language : En, Es, Fr & De
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Engineering Drug Delivery Systems is an essential resource on a variety of biomaterials engineering approaches for creating drug delivery systems that have market and therapeutic potential. The book comprehensively discusses recent advances in the fields of biomaterials and biomedical sciences in relation to drug delivery. Chapters provide a detailed introduction to various engineering approaches in designing drug delivery systems, delve into the engineering of body functions, cover the selection, design and evaluation of biomaterials, and discuss the engineering of colloids as drug carriers. The book's final chapters address the engineering of implantable drug delivery systems and advances in drug delivery technology. This book is an invaluable resource for drug delivery, materials scientists and bioengineers within the pharmaceutical industry. Examines the properties and synthesis of biomaterials for successful drug delivery Discusses the important connection between drug delivery and tissue engineering Includes techniques and approaches applicable to a wide range of users Reviews innovative technologies in drug delivery systems such as 3-D printed devices for drug delivery

Advanced Functional Polymers for Biomedical Applications

Advanced Functional Polymers for Biomedical Applications
A Book

by Masoud Mozafari,Narendra Pal Singh Chauhan

  • Publisher : Elsevier
  • Release : 2019-06-14
  • Pages : 430
  • ISBN : 0128166045
  • Language : En, Es, Fr & De
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Advanced Functional Polymers for Biomedical Applications presents novel techniques for the preparation and characterization of functionalized polymers, enabling researchers, scientists and engineers to understand and utilize their enhanced functionality in a range of cutting-edge biomedical applications. Provides systematic coverage of the major types of functional polymers, discussing their properties, preparation techniques and potential applications Presents new synthetic approaches alongside the very latest polymer processing and characterization methods Unlocks the potential of functional polymers to support ground-breaking techniques for drug and gene delivery, diagnostics, tissue engineering and regenerative medicine

Switchable Bioelectronics

Switchable Bioelectronics
A Book

by Onur Parlak

  • Publisher : CRC Press
  • Release : 2020-04-21
  • Pages : 198
  • ISBN : 1000092216
  • Language : En, Es, Fr & De
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This book reviews the rapidly emerging field of switchable interfaces and its implications for bioelectronics. The authors piece together early breakthroughs and key developments and highlight the future of switchable bioelectronics by focusing on bioelectrochemical processes based on mimicking and controlling biological environments with external stimuli as well as responsive systems for drug delivery. All chapters in the book strive to answer the fundamental question: How do living systems probe and respond to their surroundings? Following on from that, how can one transform these concepts to serve the practical world of bioelectronics? The central obstacle to this vision is the absence of versatile interfaces that are able to control and regulate the means of communication between biological and electronic systems. This book summarizes the overall progress made to date in building such interfaces at the level of individual biomolecules and focuses on the latest efforts to generate device platforms that integrate biointerfaces with electronics. Chapter 1 introduces the general concept of dynamic interfaces for bioelectronics and gives an overview of the importance of materials and systems for switchable bioelectronics, introducing the reader to different biointerfaces. Chapter 2 pieces together different types of stimuli-responsive polymers and applications. Chapter 3 lays special emphasis on stimuli-responsive polymers with tunable release kinetics and describes the importance of polymer design for delivery applications. Chapter 4 reviews the field of conformational switching in nanofibers for gas-sensing applications. Finally, Chapter 5 focuses on molecular imprinting polymers as recognition elements for sensing applications. As informative as it is lucid, this handbook makes an essential resource for advanced undergraduate- and graduate-level students in chemistry, as well as researchers in polymer science and electrochemistry, especially those with an interest in responsive polymers and biosensors.

Polymers Coatings

Polymers Coatings
Technology and Applications

by Inamuddin,Rajender Boddula,Mohd Imran Ahamed,Abdullah M. Asiri

  • Publisher : John Wiley & Sons
  • Release : 2020-05-27
  • Pages : 480
  • ISBN : 1119654998
  • Language : En, Es, Fr & De
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The explores the cutting-edge technology of polymer coatings. It discusses fundamentals, fabrication strategies, characterization techniques, and allied applications in fields such as corrosion, food, pharmaceutical, biomedical systems and electronics. It also discusses a few new innovative self-healing, antimicrobial and superhydrophobic polymer coatings. Current industrial applications and possible potential activities are also discussed.

Hyperbranched Polymers for Biomedical Applications

Hyperbranched Polymers for Biomedical Applications
A Book

by Abhijit Bandyopadhyay,Srijoni Sengupta,Tamalika Das

  • Publisher : Springer
  • Release : 2017-09-18
  • Pages : 178
  • ISBN : 9811065144
  • Language : En, Es, Fr & De
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This book presents a comprehensive study on a new class of branched polymers, known as hyperbranched polymers (HBPs). It discusses in detail the synthesis strategies for these particular classes of polymers as well as biocompatible and biodegradable HBPs, which are of increasing interest to polymer technologists due to their immense potential in biomedical applications. The book also describes the one-pot synthesis technique for HBPs, which is feasible for large-scale production, as well as HBPs’ structure-property relationship, which makes them superior to their linear counterparts. The alterable functional groups present at the terminal ends of the branches make HBPs promising candidates in the biomedical domain, and the book specifically elaborates on the suitable characteristic properties of each of the potential biological HBPs’ applications. As such, the book offers a valuable reference guide for all scientists and technologists who are interested in using these newly developed techniques to achieve faster and better treatments.

Biofunctionalization of Polymer Brush Surfaces

Biofunctionalization of Polymer Brush Surfaces
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2015
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Surface engineering of tailored materials with adjustable characteristics in relation to biological environment, is one of the main prerequisites for biotechnological applications. In recent years, advanced surface coatings in the nanometer range have drawn big attention. A special category of this group are stimuli responsive polymers tethered by one functional end to the surface. When the surface grafting density is big enough, the polymer chains are forced to stretch away from the interface due to excluded volume effects, creating a so called polymer brush. Nano-scaled polymer brushes are advantageous due to their nanostructure, which can be comparable to biological species, and their collaborative response to external stimuli. Moreover, the material design parameters such as chemistry, surface topography, charge, and surface wettability can be adjusted by using the appropriate polymer, or a combination of polymers with respect to the desired material performance. In case of binary polymer brushes, the materials' properties are switched between the properties of two constituent polymers. Besides, upon switching of external stimuli, biomodified binary polymer brushes can hide or expose biofunctionalities, on demand. Hence, they are classified as smart biomaterials' surface coatings.

Engineering Education for Sustainable Development

Engineering Education for Sustainable Development
A Capabilities Approach

by Mikateko Mathebula

  • Publisher : Routledge
  • Release : 2018-01-02
  • Pages : 204
  • ISBN : 135170916X
  • Language : En, Es, Fr & De
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This book demonstrates how the theoretical concepts of the capabilities approach can be applied in the context of engineering education, and how this could be used to add nuance to our understanding of the contribution higher education can make to human flourishing. In demonstrating the usefulness of the capability approach as a lens through which to evaluate the outputs of engineering education, the author also shows how the capability approach can be informed by, and informs, the concept of ‘sustainable development’ and discusses what pedagogical and curricula implications this may have for education for sustainable development (ESD), particularly in engineering. As such, the book builds on the work of scholars of engineering education, and scholars of university education at the nexus of development and sustainability. Engineering employers, educators and students from diverse contexts discuss both the capabilities and functions that are enlarged by engineering education and the impact these can have on pro-poor engineering or public-good professionalism. The book therefore makes an original conceptual and empirical contribution to our thinking about engineering education research. The book provides inspiration for both engineering educators and students to orient their technical knowledge and transferable skills towards the public good. It will also be of great interest to students and researchers interested in education for sustainable development more generally and to engineers who are interested in doing work that is aligned with the goals of social justice. The book will also appeal to scholars of the capability approach within higher education.

Hydrogel Sensors and Actuators

Hydrogel Sensors and Actuators
Engineering and Technology

by Gerald Gerlach,K.-F. Arndt

  • Publisher : Springer Science & Business Media
  • Release : 2009-09-24
  • Pages : 272
  • ISBN : 9783540756453
  • Language : En, Es, Fr & De
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Hydrogels are a fascinating class of polymers which show an immense ability of swelling under the influence of temperature, pH value or concentrations of different species in aqueous solutions. The volume change can amount up to several hundred percent. This unique behaviour is already used in such applications like disposable diapers, contact lenses or drug-delivery systems. The ability to perform mechanical work has been shifted the technical interest more and more towards sensors and actuators exploiting the thermo-chemo-mechano-electrical coupling within hydrogels. The accuracy requirements for such devices are much more demanding than for previous applications. Therefore, a deep knowledge of both the material and the functional properties of hydrogel sensors and actuators is needed. The monograph describes state of the art and recent developments for these materials in sensor and actuator technology.

Strategies in Regenerative Medicine

Strategies in Regenerative Medicine
Integrating Biology with Materials Design

by Matteo Santin

  • Publisher : Springer Science & Business Media
  • Release : 2009-02-28
  • Pages : 605
  • ISBN : 9780387746609
  • Language : En, Es, Fr & De
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The profound transformations occurred in our modern age have been made possible by the unique combination of new technologies. Among them, me- cine has completely changed our perception of life. Longevity has been signi- cantly extended and linked to new lifestyles. The negative impact that pathologies and ageing have always had on the quality of our life is now mitigated by the availability of treatments daily applied to many individuals worldwide. For many years, pharmacological and surgical treatments have been supported by the introduction of biomedical devices. Biomedical implants have played a key role in the development of these treatments and achieved the objective of replacing tissue and organ structures and functionalities. Gra- ally, the scientific and clinical communities have understood that replacement could be improved by materials able to interact with the tissues and to parti- pate in their metabolism and functions. This approach soon led to biomedical implants with improved clinical performances, but also to a new aspiration; rather than replacing damaged tissues and organs scientists and clinicians nowadays aim at their partial or complete regeneration. As a consequence of this ambition, the disciplines of tissue engineering and regenerative medicine have recently emerged. It is the dawn of a fascinating era where scientists from various disciplines, clinicians, and industry will need to intensify their col- borative efforts to provide our society with new and affordable solutions.

Functionalized Nanomaterials I

Functionalized Nanomaterials I
Fabrications

by Vineet Kumar,Praveen Guleria,Nandita Dasgupta,Shivendu Ranjan

  • Publisher : CRC Press
  • Release : 2020-08-10
  • Pages : 318
  • ISBN : 1351021605
  • Language : En, Es, Fr & De
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Nanomaterials contain some unique properties compared to their bulk. Their unique properties are due to the chemical nature of the material, small size, and surface functionalization. Along with control over size, the functionalization of nanomaterials also affects their compatibility to the environment and living organisms. This book provides a detailed account of nanomaterials functionalization along with a brief overview of their application. This book serves as a reference for scientific investigators including doctoral and postdoctoral scholars and undergradate and graduate students who need to have knowledge of the basics of nanomaterial functionalization, recent advancements, challenges, and opportunities in this field. This book will also provide critical and comparative data for nano-technologists and may be beneficial for industry personnel, journalists, policy makers, and the general public to help understand functionalized nanomaterials in detail and in depth. Features: This book is comprehensive and covers all aspects of functionalized nanotechnology. It describes the challenges and methods of functionalized nanomaterials synthesis for different applications. It discusses the recent findings and cutting-edge global research trends on the functionalization of nanomaterials. It emphasizes the products and market, safety, and regulatory issues of functionalized nanomaterials. It contains contributions from international experts and will be a valuable resource for researchers.

Industrial Applications for Intelligent Polymers and Coatings

Industrial Applications for Intelligent Polymers and Coatings
A Book

by Majid Hosseini,Abdel Salam Hamdy Makhlouf

  • Publisher : Springer
  • Release : 2016-05-14
  • Pages : 710
  • ISBN : 3319268937
  • Language : En, Es, Fr & De
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This book is a comprehensive collaboration on intelligent polymers and coatings for industrial applications by worldwide researchers and specialists. The authors cover the basis and fundamental aspects of intelligent polymers and coatings, challenges, and potential mechanisms and properties. They include recent and emerging industrial applications in medical, smart textile design, oil and gas, electronic, aerospace, and automobile industries as well as other applications including microsystems, sensors, and actuators, among others. The authors discuss the potential for future research in these areas for improvement and growth of marketable applications of intelligent polymers and coatings.

Polymeric Nanomaterials in Nanotherapeutics

Polymeric Nanomaterials in Nanotherapeutics
A Book

by Anonim

  • Publisher : Elsevier
  • Release : 2018-10-26
  • Pages : 558
  • ISBN : 0128139331
  • Language : En, Es, Fr & De
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Polymeric Nanomaterials in Nanotherapeutics describes how polymeric nanosensors and nanorobotics are used for biomedical instrumentation, surgery, diagnosis and targeted drug delivery for cancer, pharmacokinetics, monitoring of diabetes and healthcare. Key areas of coverage include drug administration and formulations for targeted delivery and release of active agents (drug molecules) to non-healthy tissues and cells. The book demonstrates how these are applied to dental work, wound healing, cancer, cardiovascular diseases, neurodegenerative disorders, infectious diseases, chronic inflammatory diseases, metabolic diseases, and more. Methods of administration discussed include oral, dental, topical and transdermal, pulmonary and nasal, ocular, vaginal, and brain drug delivery and targeting. Drug delivery topics treated in several subchapters includes materials for active targeting and cases study of polymeric nanomaterials in clinical trials. The toxicity and regulatory status of therapeutic polymeric nanomaterials are also examined. The book gives a broad perspective on the topic for researchers, postgraduate students and professionals in the biomaterials, biotechnology, and biomedical fields. Shows how the properties of polymeric nanomaterials can be used to create more efficient medical treatments/therapies Demonstrates the potential and range of applications of polymeric nanomaterials in disease prevention, diagnosis, drug development, and for improving treatment outcomes Accurately explains how nanotherapeutics can help in solving problems in the field through the latest technologies and formulations

Responsive Membranes and Materials

Responsive Membranes and Materials
A Book

by D. Bhattacharyya,Thomas Schäfer,S. R. Wickramasinghe,Sylvia Daunert

  • Publisher : John Wiley & Sons
  • Release : 2012-11-26
  • Pages : 432
  • ISBN : 1118389549
  • Language : En, Es, Fr & De
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The development of new multifunctional membranes and materials which respond to external stimuli, such as pH, temperature, light, biochemicals or magnetic or electrical signals, represents new approaches to separations, reactions, or recognitions. With multiple cooperative functions, responsive membranes and materials have applications which range from biopharmaceutical, to drug delivery systems to water treatment. This book covers recent advances in the generation and application of responsive materials and includes: Development and design of responsive membranes and materials Carbon nanotube membranes Tunable separations, reactions and nanoparticle synthesis Responsive membranes for water treatment Pore-filled membranes for drug release Biologically-inspired responsive materials and hydrogels Biomimetic polymer gels Responsive Membranes and Materials provides a cutting-edge resource for researchers and scientists in membrane science and technology, as well as specialists in separations, biomaterials, bionanotechnology, drug delivery, polymers, and functional materials.

Microfabrication of Stimuli-Responsive Polymers

Microfabrication of Stimuli-Responsive Polymers
A Book

by Chuanliang Feng

  • Publisher : Springer Nature
  • Release : 2021
  • Pages : 329
  • ISBN : 9813368691
  • Language : En, Es, Fr & De
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Nanotechnology in Cancer Treatment

Nanotechnology in Cancer Treatment
A Book

by Steve N. Fiering ,Robert Ivkov

  • Publisher : MDPI
  • Release : 2020-12-16
  • Pages : 224
  • ISBN : 3039363743
  • Language : En, Es, Fr & De
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The collection is diverse in the topics covered as well as the contributors, who come from across the globe. The overall topic is inherently a complex one since it integrates the exceptional complexity of cancer biology and treatment with the large and rapidly growing number of potential nanostructures and modifications that could be applied to treatment. In both cancer and nanotechnology, a very small change of a relevant variable can generate exceptional variability in biological outcome, creating inherent challenges to clinical adoption. As with many high-potential fields in medicine, the recognition of exceptional potential for nanotechnology in cancer therapy, with associated expectations of rapid clinical impact, has been followed by disappointingly slow progress that highlights not failure but rather unrealistic expectations for rapid progress. We have passed that period of expected rapid clinical impact for nanoparticle treatment of cancer and are now well-entrenched in the more realistic phase of exploiting the easiest applications, in this case packaging of established chemotherapy drugs, while carefully studying the exceptional numbers of relevant variables that must be evaluated for efficacy and safety of innovative strategies. Although never as rapid as hoped, the progress is clear and clinical impact is growing.