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Bioactive Materials for Bone Regeneration

Bioactive Materials for Bone Regeneration
A Book

by Jiang Chang,Xingdong Zhang,Kerong Dai

  • Publisher : Academic Press
  • Release : 2020-02-28
  • Pages : 248
  • ISBN : 0128135042
  • Language : En, Es, Fr & De
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Bioactive Materials for Bone Regeneration summarizes research advances on the topic, including sections on the characteristics of biomaterial-induced microenvironments, interactions of bioactive materials with stem cells and tissues, and the immunomodulatory microenvironment induced by biomaterials and its effects on osteogenesis. As the regeneration of large-size bone tissue defects represents a significant clinical challenge, this book demonstrates how new biomaterials with specific chemical and physical characteristics may interact with the host and create a unique micro-environment that actively facilitates stem cell differentiation along a specific lineage, thus stimulating tissue regeneration. Provides readers with the latest research developments in the fabrication techniques of bioactive materials for tissue regeneration and tissue engineering applications Presents the latest research advancements on how bioactive materials interact with the host and induce micro-environments for stem cell differentiation, immunomodulation and tissue regeneration Covers the methods, strategies, principle and mechanisms on constructing beneficial biomaterial microenvironments

Advanced Bioactive Inorganic Materials for Bone Regeneration and Drug Delivery

Advanced Bioactive Inorganic Materials for Bone Regeneration and Drug Delivery
A Book

by Chengtie Wu,Jiang Chang,Yin Xiao

  • Publisher : CRC Press
  • Release : 2013-03-22
  • Pages : 244
  • ISBN : 146655200X
  • Language : En, Es, Fr & De
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Bioceramics play an important role in repairing and regenerating defective or damaged bone. Annually, more than 500,000 bone graft procedures are performed in the United States and approximately 2.2 million are conducted worldwide. Advanced Bioactive Inorganic Materials for Bone Regeneration and Drug Delivery reviews the latest advances in the field of bioceramics. The book summarizes innovative concepts, bioceramic design, and methods for material synthesis and drug delivery. Offering guidance for biomedical engineering researchers and material scientists, the book explores: Novel mesoporous bioactive glasses and silicate-based ceramics for bone regeneration and drug delivery Bioactive silicate ceramics, including their mechanical properties, interaction with bone-forming cells, and in vivo osteogenesis and angiogenesis Silica nanospheres with a core-shell structure and their specific properties for controllable drug delivery The 3D-printing technique to prepare advanced bioceramic scaffolds for bone tissue engineering applications—including the preparation, mechanical strength, and biological properties of 3D-printed porous scaffolds of calcium phosphate cement and silicate bioceramics Biomimetic preparation and controllable crystal growth and biomineralization of bioceramics Inorganic and organic composite materials and their unique biological, electrical, and mechanical properties that enable the design of excellent bone regeneration and gene delivery systems A comprehensive survey of the research progress of bioceramics and their applications in bone repair and regeneration, this volume is designed to enhance study and career development for those in this field and to facilitate further research and opportunities for new solutions.

Biomaterials for Bone Regeneration

Biomaterials for Bone Regeneration
Novel Techniques and Applications

by P. Dubruel,S. Van Vlierberghe

  • Publisher : Elsevier
  • Release : 2014-06-09
  • Pages : 502
  • ISBN : 0857098101
  • Language : En, Es, Fr & De
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Novel Biomaterials for Bone Regeneration provides a comprehensive review of currently available biomaterials and how they can be applied in bone regeneration. In recent decades, there has been a shift from the idea of using biomaterials as passive substitutes for damaged bones towards the concept of biomaterials as aids for the regeneration of a host's own bone tissue. This has generated an important field of research and a range of technological developments. Part one of this book discusses a wide range of materials, including calcium phosphate cements, hydrogels, biopolymers, synthetic polymers, and shape memory polymers. Part two then turns to the processing and surface modification of biomaterials, as well as how biomaterials can be evaluated both for their mechanical properties and for immunocompatibility with the host. Finally, part three covers a variety of cellular approaches, and production and delivery of biomaterials for bone regeneration. Chapters also consider the potential of electromagnetic and ultrasonic stimulation of biomaterials to aid in the regenerative process. Novel Biomaterials for Bone Regeneration represents an important resource for academics, clinicians, and industry professionals working in the area of biomedical materials, providing them with both an overview of the current state-of-the-art, and an indication of potential future developments. Provides comprehensive coverage of novel materials, techniques, and applications of biomaterials for bone regeneration Provides vital information on the various types of materials used in bone regeneration Discusses processing, modification, and evaluation techniques of biomaterials, and looks at cellular approaches and stimulation of biomaterials for bone regeneration

Translating Biomaterials for Bone Graft

Translating Biomaterials for Bone Graft
Bench-top to Clinical Applications

by Joo L. Ong,Teja Guda

  • Publisher : CRC Press
  • Release : 2017-01-06
  • Pages : 263
  • ISBN : 1315363518
  • Language : En, Es, Fr & De
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Translating Biomaterials for Bone Graft: Bench-top to Clinical Applications brings together the current translational research in bone tissue engineering, from design to application – from materials, drugs and biologic delivery used for bone graft applications to pre-clinical and clinical considerations. The book also discusses the regulatory approval pathways, which involves consideration of the class of devices; whether they are similar to existing solutions, minimal manipulation of donor tissue or completely novel materials, drugs and biologics. These considerations drive the ability to successfully transition the latest generations of bone graft materials into the clinics. Chapters come from materials scientists, clinicians, researchers, and consultants and provide a holistic understanding of the field. As such, the book is a state-of-the-art reference to bone therapies and should appeal to clinicians, scientists, as well as students interested in the current research and/or practices in the field of bone regeneration and restoration.

Biomaterials for Bone Tissue Engineering

Biomaterials for Bone Tissue Engineering
A Book

by José A. Sanz-Herrera

  • Publisher : MDPI
  • Release : 2020-05-27
  • Pages : 244
  • ISBN : 3039289659
  • Language : En, Es, Fr & De
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Bone tissue engineering aims to develop artificial bone substitutes that partially or totally restore the natural regeneration capability of bone tissue lost under circumstances of injury, significant defects, or diseases such as osteoporosis. In this context, biomaterials are the keystone of the methodology. Biomaterials for bone tissue engineering have evolved from biocompatible materials that mimic the physical and chemical environment of bone tissue to a new generation of materials that actively interacts with the physiological environment, accelerating bone tissue growth. Mathematical modelling and simulation are important tools in the overall methodology. This book presents an overview of the current investigations and recent contributions in the field of bone tissue engineering. It includes several successful examples of multidisciplinary collaboration in this transversal area of research. The book is intended for students, researchers, and professionals of a number of disciplines, such as engineering, mathematics, physics, chemistry, biomedicine, biology, and veterinary. The book is composed of an editorial section and 16 original research papers authored by leading researchers of this discipline from different laboratories across the world

Advanced Techniques in Bone Regeneration

Advanced Techniques in Bone Regeneration
A Book

by Alessandro Rozim Zorzi,João Batista de Miranda

  • Publisher : BoD – Books on Demand
  • Release : 2016-08-31
  • Pages : 386
  • ISBN : 9535125389
  • Language : En, Es, Fr & De
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Advanced Techniques in Bone Regeneration is a book that brings together over 15 chapters, written by leading practitioners and researchers, of the latest advances in the area, including surgical techniques, new discoveries, and promising methods involving biomaterials and tissue engineering. This book is intended for all who work in the treatment of disorders involving problems with the regeneration of bone tissue, are doctors or dentists, as well as are researchers and teachers involved in this exciting field of scientific knowledge.

Biomimicked Biomaterials

Biomimicked Biomaterials
Advances in Tissue Engineering and Regenerative Medicine

by Heung Jae Chun,Rui L. Reis,Antonella Motta,Gilson Khang

  • Publisher : Springer Nature
  • Release : 2020-06-29
  • Pages : 198
  • ISBN : 9811532621
  • Language : En, Es, Fr & De
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This book is the second of two volumes that together offer a comprehensive account of cutting-edge advances in the development of biomaterials for use within tissue engineering and regenerative medicine. In this volume, which is devoted to biomimetic biomaterials, the opening section discusses bone regeneration by means of duck’s feet-derived collagen scaffold and the use of decellularized extracellular matrices. The role of various novel biomimetic hydrogels in regenerative medicine is then considered in detail. The third section focuses on the control of stem cell fate by biomimetic biomaterials, covering exosome-integrated biomaterials for bone regeneration, cellular responses to materials for biomedical engineering, and the regulation of stem cell functions by micropatterned structures. Finally, the use of nano-intelligent biocomposites in regenerative medicine is addressed, with discussion of, for example, recent advances in biphasic calcium phosphate bioceramics and blood-contacting polymeric biomaterials. The authors are recognized experts in the interdisciplinary field of regenerative medicine and the book will be of value for all with an interest in regenerative medicine based on biomaterials.

Racing for the Surface

Racing for the Surface
Antimicrobial and Interface Tissue Engineering

by Bingyun Li,Thomas Fintan Moriarty,Thomas Webster,Malcolm Xing

  • Publisher : Springer Nature
  • Release : 2020-02-28
  • Pages : 809
  • ISBN : 3030344711
  • Language : En, Es, Fr & De
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This book covers the key basics of tissue engineering as well as the latest advances in the integration of both antimicrobial and osteoinductive properties. Topics covered include osteoconductive and osteoinductive biomaterials (calcium phosphate, bone morphogenetic protein, peptides, antibodies, bioactive glasses, nanomaterials, etc.) and scaffolds. Research integrating both antimicrobial/biofilm-inhibiting and osteoinductive/osteoconductive properties and their co-delivery is detailed and their roles in clinical success are discussed. Combined with its companion volume, Racing for the Surface: Antimicrobial and Interface Tissue Engineering, this book bridges the gap between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in tissue engineering and regeneration, infection, and biomaterials and devices.

Bioactive Glasses

Bioactive Glasses
Potential Biomaterials for Future Therapy

by Gurbinder Kaur

  • Publisher : Springer
  • Release : 2017-01-02
  • Pages : 332
  • ISBN : 3319457160
  • Language : En, Es, Fr & De
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This book describes the history, origin and basic characteristics of bioactive materials. It includes a chapter dedicated to hydroxyapatite mineral, its formation and its bioactive properties. The authors address how cytotoxicity is a determining step for bioactivity. Applications of bioactive materials in the contexts of tissue regeneration, bone regeneration and cancer therapy are also covered. Silicate, metallic and mesoporous glasses are described, as well as the challenges and future prospects of research in this field.

Next-generation Biomaterials for Bone & Periodontal Regeneration

Next-generation Biomaterials for Bone & Periodontal Regeneration
A Book

by Richard John Miron,Yufeng Zhang

  • Publisher : Unknown Publisher
  • Release : 2019
  • Pages : 329
  • ISBN : 9780867157963
  • Language : En, Es, Fr & De
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An Introduction to Biomaterials, Second Edition

An Introduction to Biomaterials, Second Edition
A Book

by Jeffrey O. Hollinger

  • Publisher : CRC Press
  • Release : 2011-11-28
  • Pages : 644
  • ISBN : 1439812578
  • Language : En, Es, Fr & De
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A practical road map to the key families of biomaterials and their potential applications in clinical therapeutics, Introduction to Biomaterials, Second Edition follows the entire path of development from theory to lab to practical application. It highlights new biocompatibility issues, metrics, and statistics as well as new legislation for intellectual property. Divided into four sections (Biology, Biomechanics, Biomaterials Interactions; Biomaterials Testing, Statistics, Regulatory Considerations, Intellectual Property; Biomaterials Compositions; and Biomaterials Applications), this dramatically revised edition includes both new and revised chapters on cells, tissues, and signaling molecules in wound healing cascades, as well as two revised chapters on standardized materials testing with in vitro and in vivo paradigms consistent with regulatory guidelines. Emphasizing biocompatibility at the biomaterial-host interface, it investigates cell-cell interactions, cell-signaling and the inflammatory and complement cascades, specific interactions of protein-adsorbed materials, and other inherent biological constraints including solid-liquid interfaces, diffusion, and protein types. Unique in its inclusion of the practicalities of biomaterials as an industry, the book also covers the basic principles of statistics, new U.S. FDA information on the biomaterials-biology issues relevant to patent applications, and considerations of intellectual property and patent disclosure. With nine completely new chapters and 24 chapters extensively updated and revised with new accomplishments and contemporary data, this comprehensive introduction discusses 13 important classes of biomaterials, their fundamental and applied research, practical applications, performance properties, synthesis and testing, potential future applications, and commonly matched clinical applications. The authors include extensive references, to create a comprehensive, yet manageable didactic work that is an invaluable desk references and instructional text for undergraduates and working professionals alike.

Bone, Biomaterials & Beyond

Bone, Biomaterials & Beyond
A Book

by Antonio Barone,Ulf Nannmark

  • Publisher : Edra Masson
  • Release : 2014-04-01T00:00:00+02:00
  • Pages : 200
  • ISBN : 8821437590
  • Language : En, Es, Fr & De
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The introduction of osseointegrated dental implants soon 50 years ago has indeed revolutionized dentistry. The scientific evaluation of their use has shown good and increasingly successful treatment outcomes. A prerequisite though is the availability of sufficient bone volumes to ensure integration and acceptable aesthetic results. In this book various surgical techniques, using different augmentation materials, are described and explained. The aim has been to highlight minimally invasive surgical techniques, which leads to less risk of morbidity and reduces treatment time. Readers will enjoy a comprehensive atlas providing some practical advices for every day surgical practice based on solid scientific evidence.

Biomaterials and Stem Cells in Regenerative Medicine

Biomaterials and Stem Cells in Regenerative Medicine
A Book

by Murugan Ramalingam,Seeram Ramakrishna,Serena Best

  • Publisher : CRC Press
  • Release : 2012-07-03
  • Pages : 564
  • ISBN : 1439879265
  • Language : En, Es, Fr & De
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Work in the area of biomaterials and stem cell therapy has revealed great potential for many applications, from the treatment of localized defects and diseases to the repair and replacement of whole organs. Researchers have also begun to develop a better understanding of the cellular environment needed for optimal tissue repair and regeneration. Biomaterials and Stem Cells in Regenerative Medicine explores a range of applications for biomaterials and stem cell therapy and describes recent research on suitable cell scaffolds and substrates for tissue repair and reconstruction. Featuring contributions by experts in the field, the book explores important scientific and clinical aspects. It covers the basic science involved in structure and properties, techniques and technological innovations in processing and characterization, and applications of biomaterials and stem cells. Topics include: Polymeric systems for stem cell delivery The potential of membranes and porous scaffolds in tissue repair, including myocardial, periodontal, ophthalmic, and bone tissues The optimization of the interaction between stem cells and biomaterial substrates The source and nature of stem cells for tissue engineering applications The clinical translation of stem cell–based tissue engineering for regenerative medicine From fundamental principles to recent advances at the macro, micro, nano, and molecular scales, the book brings together current knowledge on biomaterials and stem cells in the context of regenerative medicine. It also stimulates discussion about future research directions. This unique book offers a valuable benchmark for the current status of clinically relevant research and development in stem cells and regenerative medicine. It bridges the gaps in experimental approaches and understanding among the materials science and engineering, biological sciences, and biomedical science and engineering communities, making it a valuable reference for graduate students, researchers, and practitioners working in the multidisciplinary field of biomedical research.

MSCs and Innovative Biomaterials in Dentistry

MSCs and Innovative Biomaterials in Dentistry
A Book

by Marco Tatullo

  • Publisher : Springer
  • Release : 2017-06-17
  • Pages : 188
  • ISBN : 3319556452
  • Language : En, Es, Fr & De
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This authoritative reference presents the modern concepts of mesenchymal stem cells (MSCs) and biomaterials as they pertain to the dental field. The book is organized around three main topics: MSCs biology, advanced biomaterials, and clinical applications. The chapters present basic information on stem cell biology and physiology, modern biomaterials that improve bone tissue regeneration, the biomatrices like platelet-rich fibrin (PRF) used to functionalize the biomaterials surface, the strategic and safe intraoral seats of harvesting, the new sources for MSCs, as well as the future perspectives and new challenges in these exciting fields. The contributors are top scientists with a great deal of experience in regenerative dentistry and biomedical research. They offer an international perspective and are richly cross-disciplinary, representing academia, research, and industry. MSCs and Innovative Biomaterials in Dentistry is indispensable reading for students, researchers, and clinicians who need to stay up-to-date on the cutting-edge developments of tissue engineering and regenerative medicine applied to dental sciences.

Bone Repair Biomaterials

Bone Repair Biomaterials
Regeneration and Clinical Applications

by Kendell Pawelec,J. A. Planell

  • Publisher : Woodhead Publishing
  • Release : 2018-11-29
  • Pages : 440
  • ISBN : 0081024525
  • Language : En, Es, Fr & De
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Bone Repair Biomaterials: Regeneration and Clinical Applications, Second Edition, provides comprehensive reviews on materials science, engineering principles and recent advances. Sections review the fundamentals of bone repair and regeneration, discuss the science and properties of biomaterials used for bone repair, including metals, ceramics, polymers and composites, and discuss clinical applications and considerations, with chapters on such topics as orthopedic surgery, tissue engineering, implant retrieval, and ethics of bone repair biomaterials. This second edition includes more chapters on relevant biomaterials and a greatly expanded section on clinical applications, including bone repair applications in dental surgery, spinal surgery, and maxilo-facial and skull surgery. In addition, the book features coverage of long-term performance and failure of orthopedic devices. It will be an invaluable resource for researchers, scientists and clinicians concerned with the repair and restoration of bone. Provides a comprehensive review of the materials science, engineering principles and recent advances in this important area Presents new chapters on Surface coating of titanium, using bone repair materials in dental, spinal and maxilo-facial and skull surgery, and advanced manufacturing/3D printing Reviews the fundamentals of bone repair and regeneration, addressing social, economic and clinical challenges Examines the properties of biomaterials used for bone repair, with specific chapters assessing metals, ceramics, polymers and composites

Biomaterials in Regenerative Medicine

Biomaterials in Regenerative Medicine
A Book

by Leszek A. Dobrzański

  • Publisher : BoD – Books on Demand
  • Release : 2018-02-14
  • Pages : 448
  • ISBN : 953513776X
  • Language : En, Es, Fr & De
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The book Biomaterials in Regenerative Medicine is addressed to the engineers and mainly medical practitioners as well as scientists and PhD degree students. The book indicates the progress in research and in the implementation of the ever-new biomaterials for the application of the advanced types of prosthesis, implants, scaffolds and implant-scaffolds including personalised ones. The book presents a theoretical approach to the synergy of technical, biological and medical sciences concerning materials and technologies used for medical and dental implantable devices and on metallic biomaterials. The essential contents of the book are 16 case studies provided in each of the chapters, comprehensively describing the authors' accomplishments of numerous teams from different countries across the world in advanced research areas relating to the biomaterials applied in regenerative medicine and dentistry. The detailed information collected in the book, mainly deriving from own and original research and R

Smart Materials for Tissue Engineering

Smart Materials for Tissue Engineering
Applications

by Qun Wang

  • Publisher : Royal Society of Chemistry
  • Release : 2017
  • Pages : 692
  • ISBN : 1782624848
  • Language : En, Es, Fr & De
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In the last couple of decades, research in the area of tissue engineering has witnessed tremendous progress. The focus has been on replacing or facilitating the regeneration of damaged or diseased cell, tissue or organs by applying a biomaterial support system, and a combination of cells and bioactive molecules. In addition new smart materials have been developed which provide opportunities to fabricate, characterize and utilize materials systematically to control cell behaviours and tissue formation by biomimetic topography that closely replicate the natural extracellular matrix. Following on from Smart Materials for Tissue Engineering: Fundamental Principles, this book comprehensively covers the different uses of smart materials in tissues engineering, providing a valuable resource for biochemists, materials scientists and biomedical engineers working in industry and academia.

Advances in Calcium Phosphate Biomaterials

Advances in Calcium Phosphate Biomaterials
A Book

by Besim Ben-Nissan

  • Publisher : Springer Science & Business
  • Release : 2014-04-17
  • Pages : 547
  • ISBN : 3642539807
  • Language : En, Es, Fr & De
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Advances in Calcium Phosphate Biomaterials presents a comprehensive, state-of-the-art review of the latest advances in developing calcium phosphate biomaterials and their applications in medicine. It covers the fundamental structures, synthesis methods, characterization methods, and the physical and chemical properties of calcium phosphate biomaterials, as well as the synthesis and properties of calcium phosphate-based biomaterials in regenerative medicine and their clinical applications. The book brings together these new concepts, mechanisms and methods in contributions by both young and “veteran” academics, clinicians, and researchers to forward the knowledge and expertise on calcium phosphate and related materials. Accordingly, the book not only covers the fundamentals but also open new avenues for meeting future challenges in research and clinical applications. Besim Ben-Nissan is a Professor of Chemistry and Forensic Science at the University of Technology, Sydney, Australia

Biocompatible Glasses

Biocompatible Glasses
From Bone Regeneration to Cancer Treatment

by Juliana Marchi

  • Publisher : Springer
  • Release : 2016-11-30
  • Pages : 336
  • ISBN : 331944249X
  • Language : En, Es, Fr & De
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This book focuses on the applications of bioglasses in the biomedical field. It starts with the history and evolution of bioglasses before moving on to the structure and percolation theory, and lastly investigating their current and potential future applications in various fields including dentistry, tissue engineering, bone regeneration, ophthalmology, and drug delivery. The chapters were written by a team of international experts in the field and will be of great interest not only to material scientists, but also to medical doctors and other health sector professionals.

A Tissue Regeneration Approach to Bone and Cartilage Repair

A Tissue Regeneration Approach to Bone and Cartilage Repair
A Book

by Hala Zreiqat,Colin R. Dunstan,Vicki Rosen

  • Publisher : Springer
  • Release : 2014-12-05
  • Pages : 254
  • ISBN : 3319132660
  • Language : En, Es, Fr & De
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Reviewing exhaustively the current state of the art of tissue engineering strategies for regenerating bones and joints through the use of biomaterials, growth factors and stem cells, along with an investigation of the interactions between biomaterials, bone cells, growth factors and added stem cells and how together skeletal tissues can be optimised, this book serves to highlight the importance of biomaterials composition, surface topography, architectural and mechanical properties in providing support for tissue regeneration. Maximizing reader insights into the importance of the interplay of these attributes with bone cells (osteoblasts, osteocytes and osteoclasts) and cartilage cells (chondrocytes), this book also provides a detailed reference as to how key signalling pathways are activated. The contribution of growth factors to drive tissue regeneration and stem cell recruitment is discussed along with a review the potential and challenges of adult or embryonic mesenchymal stem cells to further enhance the formation of new bone and cartilage tissues. This book serves to demonstrate the interconnectedness of biomaterials, bone/cartilage cells, growth factors and stem cells in determining the regenerative process and thus the clinical outcome.