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Bioactive Natural products in Drug Discovery

Bioactive Natural products in Drug Discovery
A Book

by Joginder Singh,Vineet Meshram,Mahiti Gupta

  • Publisher : Springer Nature
  • Release : 2020-04-30
  • Pages : 733
  • ISBN : 9811513945
  • Language : En, Es, Fr & De
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This book highlights different natural products that are derived from the plants and microbes that have shown potential as the lead compounds against infectious diseases and cancer. Natural products represent an untapped source of strikingly diverse chemotypes with novel mechanisms of action and the potential to serve as anticancer and anti-infective agents. The book discusses a range of biotechnologically valuable bioactive compounds and secondary metabolites that have been derived from plant and microorganisms from various ecological niches. It also reviews the latest developments in the field of genomics, bioinformatics and industrial fermentation for harnessing the microbial products for commercial applications. In turn, the book’s closing section reviews important biotechnological applications of various natural products. Combining the expertise of specialists in this field, the book’s goal is to promote the further investigation of natural sources for the development of standardized, safe and effective therapies.

Bioactive Natural Products Detection, Isolation, and Structural Determination

Bioactive Natural Products Detection, Isolation, and Structural Determination
A Book

by Steven M. Colegate,Russell J. Molyneux

  • Publisher : CRC Press
  • Release : 1993-09-29
  • Pages : 544
  • ISBN : 9780849343728
  • Language : En, Es, Fr & De
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Bioactive Natural Products covers all the aspects of bioactive natural product research from ethnobotanical investigations to modern, technologically assisted isolation and structural determination of active compounds. An internationally selected group of experts share their knowledge of a wide range of bioactivities and chemical compound classes. Topics in the chapters describing the modern application of detection, isolation, and structural determination techniques are strongly supported by chapters detailing and reviewing research involving various classes of bioactivity. Research areas include the immunomodulatory, antiviral, cytotoxic, anti-inflammatory, and insect behavior classes of bioactivity. Extensive referencing throughout the text is helpful to those readers not familiar with this subject and serves as a critical review for more experienced researchers. The book is also excellent for upper division or post-graduate courses.

Bioactive Natural Products

Bioactive Natural Products
Detection, Isolation, and Structural Determination, Second Edition

by Steven M. Colegate,Russell J. Molyneux

  • Publisher : CRC Press
  • Release : 2007-12-14
  • Pages : 624
  • ISBN : 1420006886
  • Language : En, Es, Fr & De
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Bioactive natural products are proving to be a rich source of novel therapeutics to both protect against and combat diseases, as well as serve as lead compounds in crop protection. Following the successful format of the first edition, this volume brings together collective research from many new contributors and emphasizes the rationale behind the

Bioactive Natural Products

Bioactive Natural Products
Opportunities and Challenges in Medicinal Chemistry

by Goutam Brahmachari

  • Publisher : World Scientific
  • Release : 2012
  • Pages : 670
  • ISBN : 9814335371
  • Language : En, Es, Fr & De
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Bioactive natural products are a rich source of novel therapeutics. Thus, the search for bioactive molecules from nature continues to play an important role in fashioning new medicinal agents. This volume, which comprises sixteen chapters written by active researchers and leading experts in natural products chemistry, brings together an overview of current discoveries in this remarkable field. It also provides information on the industrial application of natural products for medicinal purposes. This book will serve as a valuable resource for researchers to predict promising leads for developing pharmaceuticals to treat various ailments and disease manifestations.

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry
A Book

by Anonim

  • Publisher : Elsevier
  • Release : 2018-11-29
  • Pages : 540
  • ISBN : 0444641823
  • Language : En, Es, Fr & De
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Studies in Natural Products Chemistry, Volume 60 covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to rapidly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development in the pharmaceutical industry. Focuses on the chemistry of bioactive natural products Contains contributions by leading authorities in the field Presents sources of new pharmacophores

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry
A Book

by Atta-ur- Rahman

  • Publisher : Elsevier
  • Release : 2012
  • Pages : 401
  • ISBN : 0444538364
  • Language : En, Es, Fr & De
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Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate, and then determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry. The series also covers the synthesis or testing and recording of the medicinal properties of natural products. "There is a good mix of chemistry, structure elucidation, synthesis, and biology in the various chapters, thereby appealing to a diverse readership. The diagrams are clear and the writing excellent. In summary, this is another excellent volume in a very valuable series on natural products for which Professor Atta-ur-Rahman is to be congratulated...... an important and essential asset for those libraries supporting the efforts of natural product research groups." Geoffrey A. Cordell, University of Illinois, Chicago, USA, PHYTOCHEMISTRY, Vol.65, 2004 Describes the chemistry of bioactive natural products Contains contributions by leading authorities in the field A valuable source for researchers and engineers working in natural product and medicinal chemistry

Pharmaceutical and Bioactive Natural Products

Pharmaceutical and Bioactive Natural Products
A Book

by David H. Attaway,Oskar R. Zaborsky

  • Publisher : Springer
  • Release : 2013-05-30
  • Pages : 500
  • ISBN : 9781489923936
  • Language : En, Es, Fr & De
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Biotechnology may be defined as the application of scientific and engineering principles to the processing of materials by biological agents to provide goods and services (Bullet al. , 1982, p. 21) or as any technique that uses living organisms (or parts of organisms) to make or modify products, to improve plants or animals, or to develop microorganisms for specific use (OTC, 1988). In line with these broad definitions we can consider marine biotechnology as the use of marine organisms or their constituents for useful purposes in a controlled fashion. This series will explore a range of scientific advances in support of marine biotechnology. It will provide information on advances in three categories: (1) basic knowledge, (2) ap plied research and development, and (3) commercial and institutional issues. We hope the presentation of the topics will generate interest and interaction among readers in the academic world, government, and industry. This first volume examines chemical and biological properties of some natural products that are useful or potentially useful in research and in the chemical and pharmaceutical industries. One chapter describes a system for producing such substances on a large scale. Biotechnology incorporates molecular biology in order to go beyond tradi tional biochemical technology such as the production of antibiotic drugs from bacterial cultures in bioreactors. Development of the technology for production of antibiotics in this way resulted from fundamental advances in chemistry, phar macology, microbiology, and biochemical engineering.

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry
Bioactive Natural Products

by Anonim

  • Publisher : Elsevier
  • Release : 2016-06-20
  • Pages : 470
  • ISBN : 0444636102
  • Language : En, Es, Fr & De
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Studies in Natural Products Chemistry, Volume 48, provides the latest on the use of natural products from the plant and animal kingdom and the ways in which they can offer a huge diversity of chemical structures, which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then rapidly determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development. The series covers all aspects of the science, along with the synthesis, testing, and recording of the medicinal properties of natural products. With articles written by leading authorities in their respective fields of research, the book presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable resource for all those working in natural product and medicinal chemistry. Provides the latest on the use of natural products from the plant and animal kingdom and the ways in which they can offer a huge diversity of chemical structures Focuses on the chemistry of bioactive natural products and their exciting new applications in the pharmaceutical industry Presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products Contains contributions by leading authorities in the field

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry
Bioactive Natural Products

by Atta-ur-Rahman

  • Publisher : Elsevier
  • Release : 2020-03-04
  • Pages : 510
  • ISBN : 0128179031
  • Language : En, Es, Fr & De
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Studies in Natural Products Chemistry, Volume 64, covers the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques that have made it possible to rapidly isolate and determine the structures and biological activity of natural products. The book highlights these new and exciting opportunities in the field of new drug development to the pharmaceutical industry. As natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects, this book is an ideal resource on the material presented. Focuses on the chemistry of bioactive natural products Contains contributions by leading authorities in the field Presents sources of new pharmacophores

Medicinal Chemistry of Bioactive Natural Products

Medicinal Chemistry of Bioactive Natural Products
A Book

by Xiao-Tian Liang,Wei-Shuo Fang

  • Publisher : John Wiley & Sons
  • Release : 2006-03-17
  • Pages : 336
  • ISBN : 0471739332
  • Language : En, Es, Fr & De
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Current discoveries and research into bioactive naturalproducts Medicinal Chemistry of Bioactive Natural Products provides amuch-needed survey of bioactive natural products and theirapplications in medicinal chemistry. This comprehensive referencefeatures articles by some of the world's leading scientists in thefield on discovery, structure elucidation, and elegant syntheticstrategies--developed for natural products--with an emphasis on thestructure activity relationship of bioactive natural products. Thetopics have been carefully chosen on the basis of relevance tocurrent research and to importance as clinicially usefulagents. Rather than attempting to be a comprehensive encyclopedia ofbioactive natural products, Medicinal Chemistry of BioactiveNatural Products guides the reader to the key developments in thefield. By providing not only practical detail but a historicalperspective on the chemistry and biology of the compounds underconsideration, the book serves as a handy resource for researchersin their own work developing pharmaceuticals, and as an inspiringintroduction for young scientists to the dynamic field of bioactivenatural products research. Enhanced by examples with updated research results, the discussioncovers such topics as: * The chemistry and biology of epothilones * Vancomycin and other glycopeptide antibiotic derivates * Antitumor and other related activities of Taxol and itsanalogs * The antimalarial properties of the traditional Chinese medicine,Quinghaosu (artemisinin) * Huperzine A: A natural drug for the treatment of Alzheimer'sdisease * The medicinal chemistry of ginkgolides from Ginkgo biloba * Recent progress in Calophyllum coumarins as potent anti-HIVagents * Plant-derived anti-HIV agents and analogs * Chemical synthesis of annonaceous acetogenins and theirstructurally modified mimics

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry
Bioactive Natural Products (Part XI)

by Anonim

  • Publisher : Elsevier
  • Release : 2016-07-05
  • Pages : 470
  • ISBN : 9780444636027
  • Language : En, Es, Fr & De
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Studies in Natural Products Chemistry, Volume 48, provides the latest on the use of natural products from the plant and animal kingdom and the ways in which they can offer a huge diversity of chemical structures, which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then rapidly determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development. The series covers all aspects of the science, along with the synthesis, testing, and recording of the medicinal properties of natural products. With articles written by leading authorities in their respective fields of research, the book presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable resource for all those working in natural product and medicinal chemistry. Provides the latest on the use of natural products from the plant and animal kingdom and the ways in which they can offer a huge diversity of chemical structures Focuses on the chemistry of bioactive natural products and their exciting new applications in the pharmaceutical industry Presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products Contains contributions by leading authorities in the field

Bioactive Natural Products (Part E)

Bioactive Natural Products (Part E)
V24

by Atta-ur-Rahman

  • Publisher : Elsevier Science Serials
  • Release : 1988
  • Pages : 1170
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. The significance, therefore, of the Studies in Natural Product Chemistry series, edited by Professor Atta-ur-Rahman, cannot be overestimated. This volume, in accordance with previous volumes, presents us with cutting-edge contributions of great importance.

Bioactive Natural Products for the Management of Cancer: from Bench to Bedside

Bioactive Natural Products for the Management of Cancer: from Bench to Bedside
A Book

by Anil K. Sharma

  • Publisher : Springer
  • Release : 2019-07-17
  • Pages : 218
  • ISBN : 9811376077
  • Language : En, Es, Fr & De
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This book illustrates the importance of the Natural Biometabolites, which offer a rich reservoir of candidate compounds for drug discovery in the battle against cancer. Recent research and development efforts concerning anti-cancer drugs derived from natural products have led to the identification of numerous candidate molecules that inhibit cancer cell proliferation and metastasis using a variety of mechanisms. Given its scope, the book offers a valuable resource for cancer biologists and general oncologists alike, while also benefitting research professionals in Science, Nursing, Medicine, Biochemistry, Genetics and Bioscience who wish to understand the fundamentals of prognosis and prediction in tumorigenesis. Moreover, the book provides an essential platform for understanding drug resistance mechanisms and combatting the growing menace of multidrug resistance.

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry
Bioactive Natural Products (Part XII)

by Anonim

  • Publisher : Elsevier
  • Release : 2016-09-06
  • Pages : 434
  • ISBN : 0444636099
  • Language : En, Es, Fr & De
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Studies in Natural Products Chemistry: Bioactive Natural Products (Part XII) is the latest in a series that covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to quickly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. Focuses on the chemistry of bioactive natural products Contains contributions by leading authorities in the field Presents sources of new pharmacophores

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry
Bioactive Natural Products (Part M)

by Atta-ur Rahman

  • Publisher : Elsevier Science
  • Release : 2006
  • Pages : 1148
  • ISBN : 9780444527172
  • Language : En, Es, Fr & De
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Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate, determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry. The present volume contains 22 articles written by leading experts in natural product chemistry on biologically active natural products. It includes research on a variety of different classes of natural products including sesquiterpenes, quassinoids, diterpenoids, lignans, oligostilbenes, phenylethanoids, phenylpropanoid glycosides, curcumin analogues, glycosphingolipids etc. Many of these have been found to be active in a number of different disease conditions. * Timely reviews written by international authorities in the field * Topics ranging from purely chemical to very biological * The 13th volume in the series to be devoted to bioactive natural products

Qualitative and Quantitative Analysis of Bioactive Natural Products 2018

Qualitative and Quantitative Analysis of Bioactive Natural Products 2018
A Book

by Maria Carla Marcotullio

  • Publisher : MDPI
  • Release : 2019-04-04
  • Pages : 374
  • ISBN : 3038977888
  • Language : En, Es, Fr & De
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Throughout most of history, medicinal plants and their active metabolites have represented a valuable source of compounds used to prevent and to cure several diseases. Interest in natural compounds is still high as they represent a source of novel biologically/pharmacologically active compounds. Due to their high structural diversity and complexity, they are interesting structural scaffolds that can offer promising candidates for the study of new drugs, functional foods, and food additives. Plant extracts are a highly complex mixture of compounds and qualitative and quantitative analyses are necessary to ensure their quality. Furthermore, greener methods of extraction and analysis are needed today. This book is based on articles submitted for publication in the Special Issue entitled “Qualitative and Quantitative Analysis of Bioactive Natural Products” that collected original research and reviews on these topics.

Structure and Synthesis of Bioactive Natural Products

Structure and Synthesis of Bioactive Natural Products
A Book

by Zimbili Mkhize

  • Publisher : Unknown Publisher
  • Release : 2015
  • Pages : 378
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Studies in Natural Products Chemistry

Studies in Natural Products Chemistry
Bioactive Natural Products

by Atta-ur-Rahman

  • Publisher : Elsevier
  • Release : 2016-09-30
  • Pages : 434
  • ISBN : 0444637567
  • Language : En, Es, Fr & De
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Studies in Natural Products Chemistry: Bioactive Natural Products (Part XIII) is the latest in a series that covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to quickly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. Focuses on the chemistry of bioactive natural products Contains contributions by leading authorities in the field Presents sources of new pharmacophores

Bioactive Natural Products for Pharmaceutical Applications

Bioactive Natural Products for Pharmaceutical Applications
A Book

by Dilipkumar Pal

  • Publisher : Springer Nature
  • Release : 2021
  • Pages : 329
  • ISBN : 3030540278
  • Language : En, Es, Fr & De
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Bioactive Natural Products (Part D)

Bioactive Natural Products (Part D)
A Book

by Atta-ur-Rahman

  • Publisher : Elsevier
  • Release : 2000-11-03
  • Pages : 924
  • ISBN : 9780080542027
  • Language : En, Es, Fr & De
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Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. The significance, therefore, of the Studies in Natural Product Chemistry series, edited by Professor Atta-ur-Rahman, cannot be overestimated. This volume, in accordance with previous volumes, presents us with cutting-edge contributions of great importance.