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Biochemistry of Lipids, Lipoproteins and Membranes

Biochemistry of Lipids, Lipoproteins and Membranes

by Dennis E. Vance,J.E. Vance

  • Publisher : Elsevier
  • Release : 2002-12-20
  • Pages : 607
  • ISBN : 9780444511393
  • Language : En, Es, Fr & De
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The first edition of this book was published in 1985. The content of the 4th edition reflects the enormous advances that have occurred since that time in the field of lipid biochemistry. This publication is unique in that it represents a bridge between the superficial coverage of the lipid field found in basic biochemistry text books and the highly specialized material contained in scientific review articles and monographs. The book is not a collection of exhaustive reviews, but a current and readable summary of diverse aspects of lipids. It is intended as an advanced and up-to-date textbook for teachers and students who are familiar with the basic concepts of lipid biochemistry and will also serve as a general reference book for scientists studying lipids, lipoproteins and membranes.

Biochemistry of Lipids, Lipoproteins and Membranes

Biochemistry of Lipids, Lipoproteins and Membranes

by Neale Ridgway,Roger McLeod

  • Publisher : Elsevier
  • Release : 2015-07-24
  • Pages : 612
  • ISBN : 0444634495
  • Language : En, Es, Fr & De
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Biochemistry of Lipids: Lipoproteins and Membranes, Volume Six, contains concise chapters that cover a wide spectrum of topics in the field of lipid biochemistry and cell biology. It provides an important bridge between broad-based biochemistry textbooks and more technical research publications, offering cohesive, foundational information. It is a valuable tool for advanced graduate students and researchers who are interested in exploring lipid biology in more detail, and includes overviews of lipid biology in both prokaryotes and eukaryotes, while also providing fundamental background on the subsequent descriptions of fatty acid synthesis, desaturation and elongation, and the pathways that lead the synthesis of complex phospholipids, sphingolipids, and their structural variants. Also covered are sections on how bioactive lipids are involved in cell signaling with an emphasis on disease implications and pathological consequences. Serves as a general reference book for scientists studying lipids, lipoproteins and membranes and as an advanced and up-to-date textbook for teachers and students who are familiar with the basic concepts of lipid biochemistry References from current literature will be included in each chapter to facilitate more in-depth study Key concepts are supported by figures and models to improve reader understanding Chapters provide historical perspective and current analysis of each topic

Biochemistry of Lipids, Lipoproteins and Membranes

Biochemistry of Lipids, Lipoproteins and Membranes

by J.E. Vance,Dennis E. Vance

  • Publisher : Elsevier
  • Release : 1991-12-17
  • Pages : 595
  • ISBN : 9780080860800
  • Language : En, Es, Fr & De
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The second edition of this book on lipids, lipoprotein and membrane biochemistry has two major objectives - to provide an advanced textbook for students in these areas of biochemistry, and to summarise the field for scientists pursuing research in these and related fields. Since the first edition of this book was published in 1985 the emphasis on research in the area of lipid and membrane biochemistry has evolved in new directions. Consequently, the second edition has been modified to include four chapters on lipoproteins. Moreover, the other chapters have been extensively updated and revised so that additional material covering the areas of cell signalling by lipids, the assembly of lipids and proteins into membranes, and the increasing use of molecular biological techniques for research in the areas of lipid, lipoprotein and membrane biochemistry have been included. Each chapter of the textbook is written by an expert in the field, but the chapters are not simply reviews of current literature. Rather, they are written as current, readable summaries of these areas of research which should be readily understandable to students and researchers who have a basic knowledge of general biochemistry. The authors were selected for their abilities both as researchers and as communicators. In addition, the editors have carefully coordinated the chapters so that there is little overlap, yet extensive cross-referencing among chapters.

Biochemistry of Lipids, Lipoproteins and Membranes

Biochemistry of Lipids, Lipoproteins and Membranes

by Dennis E. Vance,J.E. Vance

  • Publisher : Elsevier Science Limited
  • Release : 2008-05-12
  • Pages : 631
  • ISBN :
  • Language : En, Es, Fr & De
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Second-4th eds. published in the series: New comprehensive biochemistry.

Biochemistry of Lipids, Lipoproteins and Membranes

Biochemistry of Lipids, Lipoproteins and Membranes

by N.A

  • Publisher :
  • Release : 1996
  • Pages : 553
  • ISBN : 9780444803030
  • Language : En, Es, Fr & De
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New comprehensive biochemistry

New comprehensive biochemistry

by Albert Neuberger,Laurens L. M. van Deenen

  • Publisher :
  • Release : 1984
  • Pages : 329
  • ISBN :
  • Language : En, Es, Fr & De
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Lipid Biochemistry: An Introduction

Lipid Biochemistry: An Introduction

by M. I. Gurr

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 248
  • ISBN : 9400959079
  • Language : En, Es, Fr & De
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In the preface to the Second edition, we made a prediction that many exciting developments would take place in the coming years that would change the face of a new edition. This has indeed been the case and the current edition reflects these new advances. Our picture of the structure of the fatty acid synthetase has changed dramatically, bringing a new concept in enzymology - the multicatalytic polypeptide chain. This new knowledge owes much to the exploitation of genetic mutants, the use of which is undoubtedly going to extend into many other areas of lipid biochemistry. An understanding of the control of lipid metabolism has also advanced considerably during the last decade and we have tried to reflect that here, although it will be some years before a truly integrated picture can be obtained. For this reason we have continued to deal with the control of particular aspects of lipid metabolism - fatty acids, triacylglycerols, lipoprotein- in the specific chapters but we can foresee the time when a chapter on the overall integration of lipid metabolism will be appropriate and feasible. As a particular example, the exciting new concepts of the control of cholesterol metabolism in specific tissues via the interaction of low density lipoproteins with cell surface receptors have been described in Chapter 6.

The Biology of Cholesterol and Related Steroids

The Biology of Cholesterol and Related Steroids

by N. B. Myant

  • Publisher :
  • Release : 1981
  • Pages : 910
  • ISBN :
  • Language : En, Es, Fr & De
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The Biology of Cholesterol and Related Steroids ...

Biochemistry of Lipids, Lipoproteins and Membranes

Biochemistry of Lipids, Lipoproteins and Membranes

by Dennis E. Vance,J.E. Vance

  • Publisher : Elsevier Science Serials
  • Release : 1996-08-20
  • Pages : 553
  • ISBN :
  • Language : En, Es, Fr & De
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This is the third edition of this advanced textbook, written with two major objectives in mind. One is to provide an advanced textbook covering the major areas in the fields of lipid, lipoprotein, and membrane biochemistry, and molecular biology. The second objective is to provide a clear summary of these research areas for scientists presently working in these fields. The volume provides the basis for an advanced course for students in the biochemistry of lipids, lipoproteins and membranes. The book will satisfy the need for a general reference and review book for scientists studying lipids, proteins and membranes. Excellent up-to-date reviews are available on the various topics covered. A current, readable, and critical summary of these areas of research, it will allow scientists to become familiar with recent developments related to their own research interests, and will help clinical researchers and medical students keep abreast of developments in basic science that are important for subsequent clinical advances.

Biochemistry of Lipids and Membranes

Biochemistry of Lipids and Membranes

by Dennis E. Vance,Jean E. Vance

  • Publisher : Benjamin-Cummings Publishing Company
  • Release : 1985
  • Pages : 593
  • ISBN :
  • Language : En, Es, Fr & De
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Alzheimer's Disease

Alzheimer's Disease
Challenges for the Future

by Inga Zerr

  • Publisher : BoD – Books on Demand
  • Release : 2015-07-01
  • Pages : 372
  • ISBN : 9535121375
  • Language : En, Es, Fr & De
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There is a wide scope of clinical phenomenology in Alzheimers disease, regarding the age of onset, presenting features, rate of progression and appearance of other clinical manifestation. Although clinical appearance and neuropathological hallmarks have been defining AD since its first description, major factors which trigger pathology are still unknown. The role of comorbidity is discussed controversially. Important environmental risk factors in AD development are continuous stress, low education and cardiovascular risk factors such as alcohol intake, smoking, hypertension. The role of lipids and cholesterol has been recognized, but the relevant pathogenetic steps are still to be identified. There is an urgent need to understand molecular disease pathogenesis in order to develop early therapeutic targets for the disease.

Lysosomes

Lysosomes
Biology, Diseases, and Therapeutics

by Frederick R. Maxfield,James M. Willard,Shuyan Lu

  • Publisher : John Wiley & Sons
  • Release : 2016-06-22
  • Pages : 544
  • ISBN : 1118978315
  • Language : En, Es, Fr & De
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Discussing recent findings, up-to-date research, and novel strategies, the book integrates perspectives from pharmacology, toxicology, and biochemistry to illustrate the potential of lysosomes in drug discovery and development. • Explores basic principles and properties of lysosomes that allow them to act as regulators of cell metabolism, therapeutic targets, and sites for activation of drug conjugates • Discusses the role of lysosomes in metabolism, drug targeting, apoptosis, cancer, aging, inflammation, autophagy, metabolism, toxicity, and membrane repair • Introduces new pathways in therapeutic development and new mechanisms in drug development

Structure and Dynamics of Membranes

Structure and Dynamics of Membranes
I. From Cells to Vesicles / II. Generic and Specific Interactions

by R. Lipowsky,E. Sackmann

  • Publisher : Elsevier
  • Release : 1995-06-15
  • Pages : 1052
  • ISBN : 9780080541914
  • Language : En, Es, Fr & De
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The first volume of the Handbook deals with the amazing world of biomembranes and lipid bilayers. Part A describes all aspects related to the morphology of these membranes, beginning with the complex architecture of biomembranes, continues with a description of the bizarre morphology of lipid bilayers and concludes with technological applications of these membranes. The first two chapters deal with biomembranes, providing an introduction to the membranes of eucaryotes and a description of the evolution of membranes. The following chapters are concerned with different aspects of lipids including the physical properties of model membranes composed of lipid-protein mixtures, lateral phase separation of lipids and proteins and measurement of lipid-protein bilayer diffusion. Other chapters deal with the flexibility of fluid bilayers, the closure of bilayers into vesicles which attain a large variety of different shapes, and applications of lipid vesicles and liposomes. Part B covers membrane adhesion, membrane fusion and the interaction of biomembranes with polymer networks such as the cytoskeleton. The first two chapters of this part discuss the generic interactions of membranes from the conceptual point of view. The following two chapters summarize the experimental work on two different bilayer systems. The next chapter deals with the process of contact formation, focal bounding and macroscopic contacts between cells. The cytoskeleton within eucaryotic cells consists of a network of relatively stiff filaments of which three different types of filaments have been identified. As explained in the next chapter much has been recently learned about the interaction of these filaments with the cell membrane. The final two chapters deal with membrane fusion.

Endoplasmic Reticulum

Endoplasmic Reticulum

by N. Borgese,J. Robin Harris

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 358
  • ISBN : 1461529123
  • Language : En, Es, Fr & De
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In step with the surge of interest in the endoplasmic reticulum, the current volume takes an integrated look at this functionally diverse organelle. Coverage includes protein translocation and export, lipid metabolism, antigen presentation, and many other subjects, gleaned from such diverse fields as cell biology, enzymology and membrane biochemistry, immunology, and signal transduction.

Medical Biochemistry E-Book

Medical Biochemistry E-Book

by John W Baynes,Marek H. Dominiczak

  • Publisher : Elsevier Health Sciences
  • Release : 2018-01-03
  • Pages : 702
  • ISBN : 0702073008
  • Language : En, Es, Fr & De
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Now fully revised, this acclaimed textbook efficiently links basic biochemistry with the day-to-day practice of medicine. You will learn basic science concepts and see them illustrated by clinical cases that describe patients you will likely encounter in your clinical training. You will also learn about the use of laboratory tests to diagnose and monitor the most important conditions. Brought to you in a thorough yet accessible manner, this new edition of Medical Biochemistry highlights the latest developments in regulatory and molecular biology, signal transduction, biochemistry and biomarkers of chronic disease, and bioinformatics and the ‘–omics’. It highlights the most important global medical issues: diabetes mellitus, obesity and malnutrition, cancer and atherosclerotic cardiovascular disease, and addresses the role of nutrition and exercise in medicine. Featuring a team of expert contributors that includes investigators involved in cutting-edge research as well as experienced clinicians, this book offers a unique combination of research and clinical practice tailored to today’s integrated courses. Read organ-focused chapters addressing the biochemistry of the bone, kidney, liver, lungs and muscle; and system-focused ones addressing the biochemistry of the immune and endocrine systems, neurochemistry and neurotransmission, and cancer

Lipoproteins

Lipoproteins
From Bench to Bedside

by Gerhard Kostner,Indumathi Chennamesetty

  • Publisher : BoD – Books on Demand
  • Release : 2015-10-07
  • Pages : 164
  • ISBN : 9535121782
  • Language : En, Es, Fr & De
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In mammalian blood plasma there exist some 6 major lipoprotein classes. Under physiological conditions lipoproteins are certainly beneficial as they transport nutrients and steroids to numerous organs for further metabolism. On the other hand, under pathophysiological conditions most lipoprotein classes promote atherogenesis except of HDL that are considered to be anti-atherogenic. Lipoprotein research is a wide field comprising basic science, analytical methods and clinical investigations. Thus this issue does not raise the claim to give a comprehensive picture of the current knowledge, but rather focuses on specific questions related to animal models in lipoprotein research as well as features of the most atherogenic lipoprotein, Lp(a).

The Biophysics of Cell Membranes

The Biophysics of Cell Membranes
Biological Consequences

by Richard M. Epand,Jean-Marie Ruysschaert

  • Publisher : Springer
  • Release : 2017-09-25
  • Pages : 219
  • ISBN : 9811062447
  • Language : En, Es, Fr & De
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This volume focuses on the modulation of biological membranes by specific biophysical properties. The readers are introduced to emerging biophysical approaches that mimick specific states (like membrane lipid asymmetry, membrane curvature, lipid flip-flop, lipid phase separation) that are relevant to the functioning of biological membranes. The first chapter describes innovative methods to mimic the prevailing asymmetry in biological membranes by forming asymmetrical membranes made of monolayers with different compositions. One of the chapters illustrates how physical parameters, like curvature and elasticity, can affect and modulate the interactions between lipids and proteins. This volume also describes the sensitivity of certain ion channels to mechanical forces and it presents an analysis of how cell shape is determined by both the cytoskeleton and the lipid domains in the membrane. The last chapter provides evidence that liposomes can be used as a minimal cellular model to reconstitute processes related to the origin of life. Each topic covered in this volume is presented by leading experts in the field who are able to present clear, authoritative and up-to-date reviews. The novelty of the methods proposed and their potential for a deeper molecular description of membrane functioning are particularly relevant experts in the areas of biochemistry, biophysics and cell biology, while also presenting clear and thorough introductions, making the material suitable for students in these fields as well.

Calcium: A Matter of Life or Death

Calcium: A Matter of Life or Death

by N.A

  • Publisher : Elsevier
  • Release : 2007-09-17
  • Pages : 584
  • ISBN : 9780080551937
  • Language : En, Es, Fr & De
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Calcium is a versatile carrier of signals regulating many aspects of cellular activity such as fertilization to create a new life and programmed cell death to end it. Calcium homeostasis is strictly controlled by channels, pumps and exchangers functioning as gates for calcium entry and release. Given that calcium is such a versatile messenger the field of calcium signaling is continuously and rapidly expanding. This book reviews the most recent developments in calcium signaling by leading experts in the field. It is a state-of-the-art summary of our present knowledge in this quickly growing field and provides insight into the impressive progress made in many areas of calcium signaling, while reminding us of how much remains to be learned.

Molecular Biology of the Cell

Molecular Biology of the Cell

by Bruce Alberts

  • Publisher :
  • Release : 2004
  • Pages : 329
  • ISBN : 9780815332183
  • Language : En, Es, Fr & De
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The Amphipathic Helix

The Amphipathic Helix

by Richard M. Epand

  • Publisher : CRC Press
  • Release : 1993-07-09
  • Pages : 416
  • ISBN : 9780849349263
  • Language : En, Es, Fr & De
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The Amphipathic Helix is a comprehensive volume discussing amphipathic helices in systems as diverse as serum lipoproteins, lung surfactant, cytotoxic peptides, ion channels, mitochondrial targeting, peptide hormones, G proteins, T-cell recognition, DNA binding proteins, and antifreeze proteins. The book also includes general introductory material that defines amphipathic helices, discusses methods to identify amphipathic helical segments from the amino acid sequence of a protein, illustrates how amphipathic helices can be used in the de novo design of peptide and protein structures, and describes how these helices stabilize protein structures. There is also a section on techniques to determine helix orientation in a membrane environment using polarized attenuated total reflection infrared spectroscopy or solid state NMR spectroscopy. Recent developments on all these topics have been discussed by leading experts in this reference for researchers and students in biochemistry, biophysics, and pharmacology.