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Biotechnology of Terpenoid Production from Microbial Cell Factories

Biotechnology of Terpenoid Production from Microbial Cell Factories
A Book

by Pratima Gupta,Suresh Phulara

  • Publisher : Academic Press
  • Release : 2021-04-30
  • Pages : 224
  • ISBN : 0128231785
  • Language : En, Es, Fr & De
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Biotechnology of Terpenoid Production from Microbial Cell Factories is a unique reference to help researchers, scientists and scholars explore available strategies involved in the production of terpenoid-based, value-added compounds from GRAS status (Generally Recognized as Safe by FDA) microbes to address the associated challenges for the industry. The book covers the most up-to-date information about microbial terpenoid production, including culture condition modulation for the improved and high-specificity production of terpenoid and their in-situ extraction. Each class of terpenoid is explained in detail, including their nutritional and pharmaceutical information and their molecular aspects. Provides an in-depth look at both the natural and metabolic engineering aspects of microbial terpenoid production Includes production strategies and existing challenges for each class of terpenoid from microbial sources Presents broad application opportunities of terpenoids such as food additives, pharmaceuticals and fragrances Includes brief chapter summaries and a glossary for each chapter to simplify technical applications

Microbial Cell Factories Engineering for Production of Biomolecules

Microbial Cell Factories Engineering for Production of Biomolecules
A Book

by Vijai Singh

  • Publisher : Academic Press
  • Release : 2021-02-26
  • Pages : 488
  • ISBN : 0128214783
  • Language : En, Es, Fr & De
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Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synthesis, design of biosynthetic pathways, synthetic biology tools, biosensors, cell-free systems, computer-aided design, OMICS tools, CRISPR/Cas systems, and many more. Although it is not easy to find relevant information collated in a single volume, the book covers the production of a wide range of biomolecules from several MCFs, including Escherichia coli, Bacillus subtilis, Pseudomonas putida, Streptomyces, Corynebacterium, Cyanobacteria, Saccharomyces cerevisiae, Pichia pastoris and Yarrowia lipolytica, and algae, among many others. This will be an excellent platform from which scientific knowledge can grow and widen in MCF engineering research for the production of biomolecules. Needless to say, the book is a valuable source of information not only for researchers designing cell factories, but also for students, metabolic engineers, synthetic biologists, genome engineers, industrialists, stakeholders and policymakers interested in harnessing the potential of MCFs in several fields. Offers basic understanding and a clear picture of various MCFs Explains several tools and technologies, including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer-aided design, and OMICS tools, among others Harnesses the potential of engineered MCFs to produce a wide range of biomolecules for industrial, therapeutic, pharmaceutical, nutraceutical and biotechnological applications Highlights the advances, challenges, and future opportunities in designing MCFs

Microbial Cell Factories

Microbial Cell Factories
A Book

by Deepansh Sharma,Baljeet Singh Saharan

  • Publisher : CRC Press
  • Release : 2018-03-22
  • Pages : 394
  • ISBN : 1351668056
  • Language : En, Es, Fr & De
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Microbial Cell Factories is a conceptual, reference-based source including chapters covering microbial cell factories for industrial developments, microbial biotechnology, sustainable environmental solutions, agriculture practices, microorganisms in food processing, metabolites as next generation food additives/food processing, and microbial cell factories in alternative energy fuel generation. The book highlights trends and developments in the field of microbial products, written by an international team of leading academic and research scholars. Key Selling Features: Highlights trends and developments in microbial biotechnology Systematically reviews microbial cell factories Explores the potential of microbial cell derived industrial production Synthesizes information on environmental and agricultural uses of microbial biotechnology Contributions from an international team of leading scholars

Biotechnology of Bioactive Compounds

Biotechnology of Bioactive Compounds
Sources and Applications

by Vijai Kumar Gupta,Maria G. Tuohy,Anthonia O'Donovan,Mohtashim Lohani

  • Publisher : John Wiley & Sons
  • Release : 2015-04-20
  • Pages : 736
  • ISBN : 1118733495
  • Language : En, Es, Fr & De
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Bioactive compounds play a central role in high-value product development in the chemical industry. Bioactive compounds have been identified from diverse sources and their therapeutic benefits, nutritional value and protective effects in human and animal healthcare have underpinned their application as pharmaceuticals and functional food ingredients. The orderly study of biologically active products and the exploration of potential biological activities of these secondary metabolites, including their clinical applications, standardization, quality control, mode of action and potential biomolecular interactions, has emerged as one of the most exciting developments in modern natural medicine. Biotechnology of Bioactive Compounds describes the current stage of knowledge on the production of bioactive compounds from microbial, algal and vegetable sources. In addition, the molecular approach for screening bioactive compounds is also discussed, as well as examples of applications of these compounds on human health. The first half of the book comprises information on diverse sources of bioactive compounds, ranging from microorganisms and algae to plants and dietary foods. The second half of the book reviews synthetic approaches, as well as selected bioactivities and biotechnological and biomedical potential. The bioactive compounds profiled include compounds such as C-phycocyanins, glycosides, phytosterols and natural steroids. An overview of the usage of bioactive compounds as antioxidants and anti-inflammatory agents, anti-allergic compounds and in stem cell research is also presented, along with an overview of the medicinal applications of plant-derived compounds. Biotechnology of Bioactive Compounds will be an informative text for undergraduate and graduate students of bio-medicinal chemistry who are keen to explore the potential of bioactive natural products. It also provides useful information for scientists working in various research fields where natural products have a primary role.

Current Developments in Biotechnology and Bioengineering

Current Developments in Biotechnology and Bioengineering
Synthetic Biology, Cell Engineering and Bioprocessing Technologies

by Sudhir P. P. Singh,Ashok Pandey,Guocheng Du,Sudesh Kumar

  • Publisher : Elsevier
  • Release : 2018-11-20
  • Pages : 442
  • ISBN : 044464086X
  • Language : En, Es, Fr & De
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Current Developments in Biotechnology and Bioengineering: Synthetic Biology, Cell Engineering and Bioprocessing Technologies covers the current perspectives and outlook of synthetic biology in the agriculture, food and health sectors. This book begins with the basics about synthetic biology and cell engineering, and then explores this in more detail, focusing on topics like applications of synthetic biology, industrial bioprocesses, and future perspectives. Information on cell engineering is also presented, and manipulation in endogenous metabolic network is studied alongside advanced topics such as fine tuning of metabolic pathways, de novo biosynthetic pathway design, enzyme engineering targeted to improved kinetics and stability, and potential applications of the novel biological systems in bioprocess technology to achieve the production of value-added compounds with specific biological activities. Assists in developing a conceptual understanding of synthetic biology and cellular and metabolic engineering. Includes comprehensive information on new developments and advancements. Lists applications of synthetic biology in agriculture, food, and health

Cyanobacteria Biotechnology

Cyanobacteria Biotechnology
A Book

by Paul Hudson

  • Publisher : John Wiley & Sons
  • Release : 2021-04-20
  • Pages : 560
  • ISBN : 3527824928
  • Language : En, Es, Fr & De
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Unites a biological and a biotechnological perspective on cyanobacteria, and includes the industrial aspects and applications of cyanobacteria Cyanobacteria Biotechnology offers a guide to the interesting and useful features of cyanobacteria metabolism that keeps true to a biotechnology vision. In one volume the book brings together both biology and biotechnology to illuminate the core acpects and principles of cyanobacteria metabolism. Designed to offer a practical approach to the metabolic engineering of cyanobacteria, the book contains relevant examples of how this metabolic "module" is currently being engineered and how it could be engineered in the future. The author includes information on the requirements and real-world experiences of the industrial applications of cyanobacteria. This important book: Brings together biology and biotechnology in order to gain insight into the industrial relevant topic of cyanobacteria Introduces the key aspects of the metabolism of cyanobacteria Presents a grounded, practical approach to the metabolic engineering of cyanobacteria Offers an analysis of the requirements and experiences for industrial cyanobacteria Provides a framework for readers to design their own processes Written for biotechnologists, microbiologists, biologists, biochemists, Cyanobacteria Biotechnology provides a systematic and clear volume that brings together the biological and biotechnological perspective on cyanobacteria.

Systems Biology

Systems Biology
A Book

by Jens Nielsen,Stefan Hohmann

  • Publisher : John Wiley & Sons
  • Release : 2017-03-15
  • Pages : 600
  • ISBN : 3527696172
  • Language : En, Es, Fr & De
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Comprehensive coverage of the many different aspects of systems biology, resulting in an excellent overview of the experimental and computational approaches currently in use to study biological systems. Each chapter represents a valuable introduction to one specific branch of systems biology, while also including the current state of the art and pointers to future directions. Following different methods for the integrative analysis of omics data, the book goes on to describe techniques that allow for the direct quantification of carbon fluxes in large metabolic networks, including the use of 13C labelled substrates and genome-scale metabolic models. The latter is explained on the basis of the model organism Escherichia coli as well as the human metabolism. Subsequently, the authors deal with the application of such techniques to human health and cell factory engineering, with a focus on recent progress in building genome-scale models and regulatory networks. They highlight the importance of such information for specific biological processes, including the ageing of cells, the immune system and organogenesis. The book concludes with a summary of recent advances in genome editing, which have allowed for precise genetic modifications, even with the dynamic control of gene expression. This is part of the Advances Biotechnology series, covering all pertinent aspects of the field with each volume prepared by eminent scientists who are experts on the topic in question.

Engineering the Microbial Platform for the Production of Biologics and Small-Molecule Medicines

Engineering the Microbial Platform for the Production of Biologics and Small-Molecule Medicines
A Book

by Dipesh Dhakal,Eung-Soo Kim,Mattheos Koffas

  • Publisher : Frontiers Media SA
  • Release : 2019-12-23
  • Pages : 329
  • ISBN : 2889632539
  • Language : En, Es, Fr & De
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Cyanobacteria

Cyanobacteria
From Basic Science to Applications

by A.K. Mishra,D.N. Tiwari,A.N. Rai

  • Publisher : Academic Press
  • Release : 2018-11-30
  • Pages : 541
  • ISBN : 0128146680
  • Language : En, Es, Fr & De
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Cyanobacteria constitute the most widely distributed group of photosynthetic prokaryotes found in almost all realms of the earth and play an important role in Earth’s nitrogen and carbon cycle. The gradual transformation from reducing atmosphere to oxidizing atmosphere was a turning point in the evolutionary history of the earth and made conditions for present life forms possible. Cyanobacteria: From Basic Science to Applications is the first reference volume that comprehensively discusses all aspects of cyanobacteria, including the diverse mechanisms of cyanobacteria for the advancement of cyanobacterial abilities, towards higher biofuel productivity, enhanced tolerance to environmental stress and bioactive compounds and potential for biofertilizers. Describes cyanobacterial diversity, stress biology, and biotechnological aspects of cyanobacteria Explores the global importance of cyanobacteria Provides a broad compilation of research that deals with cyanobacterial stress responses in both controlled laboratory conditions as well as in their natural environment

Industrial Biotechnology

Industrial Biotechnology
Products and Processes

by Christoph Wittmann

  • Publisher : John Wiley & Sons
  • Release : 2017-03-06
  • Pages : 640
  • ISBN : 3527341811
  • Language : En, Es, Fr & De
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The latest volume in the Advanced Biotechnology series provides an overview of the main product classes and platform chemicals produced by biotechnological processes today, with applications in the food, healthcare and fine chemical industries. Alongside the production of drugs and flavors as well as amino acids, bio-based monomers and polymers and biofuels, basic insights are also given as to the biotechnological processes yielding such products and how large-scale production may be enabled and improved. Of interest to biotechnologists, bio and chemical engineers, as well as those working in the biotechnological, chemical, and food industries.

Metabolic Pathway Engineering

Metabolic Pathway Engineering
Analysis and Applications in the Life Sciences

by Jean F. Challacombe

  • Publisher : CRC Press
  • Release : 2021-07-15
  • Pages : 156
  • ISBN : 1000260542
  • Language : En, Es, Fr & De
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Metabolic systems engineering combines the tools and approaches of systems biology, synthetic biology, and evolutionary engineering. This book reviews studies on metabolism, from the earliest work of Lavoisier and Buchner to current cutting-edge research in metabolic systems engineering. This technology has been used in bioengineering applications to create high-performing microbes and plants that produce important chemicals, pharmaceuticals, crops, and other natural products. Current applications include optimizing metabolic pathways to enhance degradation of biomass for biofuel production and accelerated processing of environmental waste products and contaminants. The book includes examples to illustrate the applications of this technology in the optimization of metabolic pathways to create robust industrial strains as well as in the engineering of biological processes involving health and diseases of humans, animals, and plants. Written by a seasoned computational biologist with many years of experience in genomics, bioinformatics, and systems biology, this book will appeal to anyone interested in metabolic systems analysis and metabolic pathway engineering.

Advances in Applied Microbiology

Advances in Applied Microbiology
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2021-04-29
  • Pages : 148
  • ISBN : 0323850782
  • Language : En, Es, Fr & De
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Advances in Applied Microbiology, Volume 114 continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topic of microbiology, with this release focusing on recent advances in the biosynthesis of isoprenoids in the engineered Saccharomyces cerevisiae. Contains contributions from leading authorities in the field Informs and updates on all the latest developments in the field of microbiology Includes discussions on the role of specific molecules in pathogen life stages, interactions, and much more

Microbiological Advancements for Higher Altitude Agro-Ecosystems & Sustainability

Microbiological Advancements for Higher Altitude Agro-Ecosystems & Sustainability
A Book

by Reeta Goel,Ravindra Soni,Deep Chandra Suyal

  • Publisher : Springer Nature
  • Release : 2020-03-13
  • Pages : 491
  • ISBN : 9811519021
  • Language : En, Es, Fr & De
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The book explores the challenges and opportunities associated with high-altitude agro-ecosystems and the factors that influence them. It discusses the various indigenous agricultural practices and approaches, as well as the microbiology of mountain & hill agro-ecosystems, providing a comprehensive overview of the various factors that control the microbiome at high altitudes. The contributions examine microbiological advances, such as use of “omics” technologies for hill agriculture and environmental sustainability, and explore the use of nanotechnology for agricultural and environmental sustainability at higher altitudes. The book also describes various aspects of low-temperature microbiology in the context of high-altitude farming and environmental sustainability.

Microbial Production of Food Ingredients, Enzymes and Nutraceuticals

Microbial Production of Food Ingredients, Enzymes and Nutraceuticals
A Book

by Brian McNeil,David Archer,Ioannis Giavasis,Linda Harvey

  • Publisher : Elsevier
  • Release : 2013-03-21
  • Pages : 656
  • ISBN : 0857093541
  • Language : En, Es, Fr & De
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Bacteria, yeast, fungi and microalgae can act as producers (or catalysts for the production) of food ingredients, enzymes and nutraceuticals. With the current trend towards the use of natural ingredients in foods, there is renewed interest in microbial flavours and colours, food bioprocessing using enzymes and food biopreservation using bacteriocins. Microbial production of substances such as organic acids and hydrocolloids also remains an important and fast-changing area of research. Microbial production of food ingredients, enzymes and nutraceuticals provides a comprehensive overview of microbial production of food ingredients, enzymes and nutraceuticals. Part one reviews developments in the metabolic engineering of industrial microorganisms and advances in fermentation technology in the production of fungi, yeasts, enzymes and nutraceuticals. Part two discusses the production and application in food processing of substances such as carotenoids, flavonoids and terponoids, enzymes, probiotics and prebiotics, bacteriocins, microbial polysaccharides, polyols and polyunsaturated fatty acids. Microbial production of food ingredients, enzymes and nutraceuticals is an invaluable guide for professionals in the fermentation industry as well as researchers and practitioners in the areas of biotechnology, microbiology, chemical engineering and food processing. Provides a comprehensive overview of microbial flavours and colours, food bioprocessing using enzymes and food biopreservation using bacteriocins Begins with a review of key areas of systems biology and metabolic engineering, including methods and developments for filamentous fungi Analyses the use of microorganisms for the production of natural molecules for use in foods, including microbial production of food flavours and carotenoids

Principles and Applications of Fermentation Technology

Principles and Applications of Fermentation Technology
A Book

by Arindam Kuila,Vinay Sharma

  • Publisher : John Wiley & Sons
  • Release : 2018-09-05
  • Pages : 480
  • ISBN : 1119460263
  • Language : En, Es, Fr & De
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The book covers all aspects of fermentation technology such as principles, reaction kinetics, scaling up of processes, and applications. The 20 chapters written by subject matter experts are divided into two parts: Principles and Applications. In the first part subjects covered include: Modelling and kinetics of fermentation technology Sterilization techniques used in fermentation processes Design and types of bioreactors used in fermentation technology Recent advances and future prospect of fermentation technology The second part subjects covered include: Lactic acid and ethanol production using fermentation technology Various industrial value-added product biosynthesis using fermentation technology Microbial cyp450 production and its industrial application Polyunsaturated fatty acid production through solid state fermentation Application of oleaginous yeast for lignocellulosic biomass based single cell oil production Utilization of micro-algal biomass for bioethanol production Poly-lactide production from lactic acid through fermentation technology Bacterial cellulose and its potential impact on industrial applications

Synthetic biology applications in industrial microbiology

Synthetic biology applications in industrial microbiology

by Weiwen Zhang,David Nielsen

  • Publisher : Frontiers E-books
  • Release : 2014-12-03
  • Pages : 329
  • ISBN : 288919342X
  • Language : En, Es, Fr & De
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Exponentially increasing information on biological organisms coupled with increasing computational power in the past decade have broadened the perspective of fundamental biological research, bringing about considerable promise and unprecedented potential for practical applications in biotechnology. As one emergent discipline, synthetic biology aims to design and engineer novel biologically-based parts, devices, and systems, in addition to redesigning existing, natural biological systems. Although previously relegated to demonstration studies, more recent research in synthetic biology has focused on the rational engineering of industrial microorganisms with the potential to address many of society’s critical challenges. Within the realm of industrial microbiology, progress in the field of synthetic biology has enabled the development of, for example, new biosynthetic pathways for the production of renewable fuels and chemicals, programmable logic controls to regulate and optimize cell function, and robust microbes for the destruction of harmful environmental contaminants. Some of the exciting examples included producing anti-malarial drug, anti- cancer taxol precursor and various biofuel molecules in E. coli and yeast. In addition, these researches have also greatly enhanced our understanding of the cellular machinery and its regulation in some of the industry important microbes, laying an important foundation for further design and engineering of biological function for even greater application. For these reasons, we present here a collection of articles from the leading edge of the field of synthetic biology, with a specific focus on the development in industrial microorganisms. It is the intent of this collection to reach a wide audience whose interests and expertise spans from development of novel synthetic biology methodologies and theories (both experimental and computational) to practical applications seeking to address issues facing the world today.

Circadian Rhythms in Bacteria and Microbiomes

Circadian Rhythms in Bacteria and Microbiomes
A Book

by Carl Hirschie Johnson

  • Publisher : Springer Nature
  • Release : 2021
  • Pages : 329
  • ISBN : 3030721582
  • Language : En, Es, Fr & De
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Bioprocessing for Biomolecules Production

Bioprocessing for Biomolecules Production
A Book

by Gustavo Molina,Vijai Kumar Gupta,Brahma N. Singh,Nicholas Gathergood

  • Publisher : John Wiley & Sons
  • Release : 2020-01-13
  • Pages : 536
  • ISBN : 1119434327
  • Language : En, Es, Fr & De
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Presents the many recent innovations and advancements in the field of biotechnological processes This book tackles the challenges and potential of biotechnological processes for the production of new industrial ingredients, bioactive compounds, biopolymers, energy sources, and compounds with commercial/industrial and economic interest by performing an interface between the developments achieved in the recent worldwide research and its many challenges to the upscale process until the adoption of commercial as well as industrial scale. Bioprocessing for Biomolecules Production examines the current status of the use and limitation of biotechnology in different industrial sectors, prospects for development combined with advances in technology and investment, and intellectual and technical production around worldwide research. It also covers new regulatory bodies, laws and regulations, and more. Chapters look at biological and biotechnological processes in the food, pharmaceutical, and biofuel industries; research and production of microbial PUFAs; organic acids and their potential for industry; second and third generation biofuels; the fermentative production of beta-glucan; and extremophiles for hydrolytic enzymes productions. The book also looks at bioethanol production from fruit and vegetable wastes; bioprocessing of cassava stem to bioethanol using soaking in aqueous ammonia pretreatment; bioprospecting of microbes for bio-hydrogen production; and more. Provides up to date information about the advancements made on the production of important biotechnological ingredients Complete visualization of the general developments of world research around diverse products and ingredients of technological, economic, commercial and social importance Investigates the use and recovery of agro-industrial wastes in biotechnological processes Includes the latest updates from regulatory bodies for commercialization feasibility Offering new products and techniques for the industrial development and diversification of commercial products, Bioprocessing for Biomolecules Production is an important book for graduate students, professionals, and researchers involved in food technology, biotechnology; microbiology, bioengineering, biochemistry, and enzymology.

Synthetic Biology and Metabolic Engineering in Plants and Microbes Part B: Metabolism in Plants

Synthetic Biology and Metabolic Engineering in Plants and Microbes Part B: Metabolism in Plants
A Book

by Anonim

  • Publisher : Elsevier
  • Release : 2016-07-29
  • Pages : 446
  • ISBN : 0128111232
  • Language : En, Es, Fr & De
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Synthetic Biology and Metabolic Engineering in Plants and Microbes, Part B, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods, synthetic biology, and metabolic engineering in plants and microbes, and includes sections on such topics as the usage of integrases in microbial engineering, biosynthesis, and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways. Continues the legacy of this premier serial with quality chapters authored by leaders in the field of enzymology Contains two volumes covering research methods in synthetic biology and metabolic engineering in plants and microbes Includes sections on such topics as the uses of integrases in microbial engineering, biosynthesis and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways

Carotenoids

Carotenoids
A Book

by Dragan Cvetkovic,Goran Nikolic

  • Publisher : BoD – Books on Demand
  • Release : 2017-06-14
  • Pages : 232
  • ISBN : 9535132113
  • Language : En, Es, Fr & De
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Carotenoids are one of the most widespread pigment groups distributed in nature; more than 700 natural carotenoids have been described so far. These pigments are known for versatile roles they play in living organisms; however, their most pivotal function is involvement in scavenging of reactive oxygen species and photoprotection. In the same time, carotenoids as natural pigments with important biological activities, such as antioxidant and provitamin A activity, have a great potential in the food, feed and pharmaceutical industries. They can be either extracted from plants and algae or synthesized by various microorganisms, including bacteria, yeasts, filamentous fungi and microalgae.