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Bones and Cartilage

Bones and Cartilage
Developmental and Evolutionary Skeletal Biology

by Brian K. Hall

  • Publisher : Academic Press
  • Release : 2014-12-23
  • Pages : 920
  • ISBN : 0124166857
  • Language : En, Es, Fr & De
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Bones and Cartilage provides the most in-depth review and synthesis assembled on the topic, across all vertebrates. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage develop in embryos and are maintained in adults, how bone is repaired when we break a leg, or regenerates when a newt grows a new limb, or a lizard a new tail. The second edition of Bones and Cartilage includes the most recent knowledge of molecular, cellular, developmental and evolutionary processes, which are integrated to outline a unified discipline of developmental and evolutionary skeletal biology. Additionally, coverage includes how the molecular and cellular aspects of bones and cartilage differ in different skeletal systems and across species, along with the latest studies and hypotheses of relationships between skeletal cells and the most recent information on coupling between osteocytes and osteoclasts All chapters have been revised and updated to include the latest research. Offers complete coverage of every aspect of bone and cartilage, with updated references and extensive illustrations Integrates development and evolution of the skeleton, as well a synthesis of differentiation, growth and patterning Treats all levels from molecular to clinical, embryos to evolution, and covers all vertebrates as well as invertebrate cartilages Includes new chapters on evolutionary skeletal biology that highlight normal variation and variability, and variation outside the norm (neomorphs, atavisms) Updates hypotheses on the origination of cartilage using new phylogenetic, cellular and genetic data Covers stem cells in embryos and adults, including mesenchymal stem cells and their use in genetic engineering of cartilage, and the concept of the stem cell niche

Bones and Cartilage

Bones and Cartilage
Developmental and Evolutionary Skeletal Biology

by Brian K. Hall

  • Publisher : Elsevier
  • Release : 2005-06-20
  • Pages : 792
  • ISBN : 9780080454153
  • Language : En, Es, Fr & De
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Bones and Cartilage provides the most in-depth review ever assembled on the topic. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage is developed in embryos and are maintained in adults, how bone reappears when we break a leg, or even regenerates when a newt grows a new limb, or a lizard a tail. This book also looks at the molecules and cells that make bones and cartilages and how they differ in various parts of the body and across species. It answers such questions as “Is bone always bone? “Do bones that develop indirectly by replacing other tissues, such as marrow, tendons or ligaments, differ from one another? “Is fish bone the same as human bone? “Can sharks even make bone? and many more. * Complete coverage of every aspect of bone and cartilage * Full of interesting and unusual facts * The only book available that integrates development and evolution of the skeleton * Treats all levels from molecular to clinical, embryos to evolution * Written in a lively, accessible style * Extensively illustrated and referenced * Integrates analysis of differentiation, growth and patterning * Covers all the vertebrates as well as invertebrate cartilages * Identifies the stem cells in embryos and adults that can make skeletal tissues

Bones and Cartilage

Bones and Cartilage
Developmental and Evolutionary Skeletal Biology

by Brian K. Hall

  • Publisher : Academic Press
  • Release : 2015-01-05
  • Pages : 920
  • ISBN : 9780124166783
  • Language : En, Es, Fr & De
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Bones and Cartilage provides the most in-depth review and synthesis assembled on the topic, across all vertebrates. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage develop in embryos and are maintained in adults, how bone is repaired when we break a leg, or regenerates when a newt grows a new limb, or a lizard a new tail. The second edition of Bones and Cartilage includes the most recent knowledge of molecular, cellular, developmental and evolutionary processes, which are integrated to outline a unified discipline of developmental and evolutionary skeletal biology. Additionally, coverage includes how the molecular and cellular aspects of bones and cartilage differ in different skeletal systems and across species, along with the latest studies and hypotheses of relationships between skeletal cells and the most recent information on coupling between osteocytes and osteoclasts All chapters have been revised and updated to include the latest research. Offers complete coverage of every aspect of bone and cartilage, with updated references and extensive illustrations Integrates development and evolution of the skeleton, as well a synthesis of differentiation, growth and patterning Treats all levels from molecular to clinical, embryos to evolution, and covers all vertebrates as well as invertebrate cartilages Includes new chapters on evolutionary skeletal biology that highlight normal variation and variability, and variation outside the norm (neomorphs, atavisms) Updates hypotheses on the origination of cartilage using new phylogenetic, cellular and genetic data Covers stem cells in embryos and adults, including mesenchymal stem cells and their use in genetic engineering of cartilage, and the concept of the stem cell niche

A Tissue Regeneration Approach to Bone and Cartilage Repair

A Tissue Regeneration Approach to Bone and Cartilage Repair
A Book

by Hala Zreiqat,Colin R. Dunstan,Vicki Rosen

  • Publisher : Springer
  • Release : 2014-12-05
  • Pages : 254
  • ISBN : 3319132660
  • Language : En, Es, Fr & De
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Reviewing exhaustively the current state of the art of tissue engineering strategies for regenerating bones and joints through the use of biomaterials, growth factors and stem cells, along with an investigation of the interactions between biomaterials, bone cells, growth factors and added stem cells and how together skeletal tissues can be optimised, this book serves to highlight the importance of biomaterials composition, surface topography, architectural and mechanical properties in providing support for tissue regeneration. Maximizing reader insights into the importance of the interplay of these attributes with bone cells (osteoblasts, osteocytes and osteoclasts) and cartilage cells (chondrocytes), this book also provides a detailed reference as to how key signalling pathways are activated. The contribution of growth factors to drive tissue regeneration and stem cell recruitment is discussed along with a review the potential and challenges of adult or embryonic mesenchymal stem cells to further enhance the formation of new bone and cartilage tissues. This book serves to demonstrate the interconnectedness of biomaterials, bone/cartilage cells, growth factors and stem cells in determining the regenerative process and thus the clinical outcome.

Handbook of Histology Methods for Bone and Cartilage

Handbook of Histology Methods for Bone and Cartilage
A Book

by Yuehuei H. An,Kylie L. Martin

  • Publisher : Springer Science & Business Media
  • Release : 2003-05-01
  • Pages : 588
  • ISBN : 1592594174
  • Language : En, Es, Fr & De
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Histotechnology and histomorphometry are the major methodologies in bone and cartila- related research. Handbook of Histology Methods for Bone and Cartilage is an outgrowth of the editors’ own quest for information on bone and cartilage histology and histomorphometry. It is designed to be an experimental guide for personnel who work in the areas of basic and clinical bone and cartilage, orthopedic, or dental research. It is the first inclusive and organized reference book on histological and histomorphometrical techniques on bone and cartilage specimens. The topic has not previously been covered adequately by any existing books in the field. Handbook of Histology Methods for Bone and Cartilage has six major parts and is designed to be concise as well as inclusive, and more practical than theoretical. The text is simple and straightforward. Large numbers of tables, line drawings, and micro- or macro-photographs, are used to help readers better understand the content. Full bibliographies at the end of each chapter guide readers to more detailed information. A book of this length cannot discuss every method for bone and cartilage histology that has been used over the years, but it is hoped that major methods and their applications have been included.

Biomechanics of Hard Tissues

Biomechanics of Hard Tissues
Modeling, Testing, and Materials

by Andreas Öchsner,Waqar Ahmed

  • Publisher : John Wiley & Sons
  • Release : 2011-08-08
  • Pages : 322
  • ISBN : 3527642064
  • Language : En, Es, Fr & De
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This monograph assembles expert knowledge on the latest biomechanical modeling and testing of hard tissues, coupled with a concise introduction to the structural and physical properties of bone and cartilage. A strong focus lies on the current advances in understanding bone structure and function from a materials science perspective, providing practical knowledge on how to model, simulate and predict the mechanical behavior of bone. The book presents directly applicable methods for designing and testing the performance of artificial bones and joint replacements, while addressing innovative and safe approaches to stimulated bone regeneration essential for clinical researchers.

Anatomy and Physiology

Anatomy and Physiology
A Book

by J. Gordon Betts,Peter DeSaix,Jody E. Johnson,Oksana Korol,Dean H. Kruse,Brandon Poe,James A. Wise,Mark Womble,Kelly A. Young

  • Publisher : Unknown Publisher
  • Release : 2013-04-25
  • Pages : 329
  • ISBN : 9781947172807
  • Language : En, Es, Fr & De
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Cartilage and Bone Development and Its Disorders

Cartilage and Bone Development and Its Disorders
A Book

by Cecilia Camacho-Hübner,O. Nilsson,L. Saevendahl

  • Publisher : Karger Medical and Scientific Publishers
  • Release : 2011
  • Pages : 120
  • ISBN : 3805597924
  • Language : En, Es, Fr & De
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Covering recent advances in basic and clinical research In systemic childhood diseases, including cancer, gastrointestinal, pulmonary and cardiac disorders, childhood growth is severely impaired. In addition, almost 400 known genetic diseases inhibit the ability of the growth plate to form new bone, leaving affected children with growth failure and bony deformities which can severely impact their quality of life and may lead to morbidity and early mortality. This book provides a comprehensive review of bone and cartilage development, growth and disease. Focusing on novel treatment strategies, regulatory signals and molecular mechanisms are discussed in relation to the diseases affecting them. Furthermore, novel methodologies in bone and cartilage research based on recent advances in skeletal stem cell biology, cartilage tissue engineering and allele-specific gene silencing is covered. Providing insight into the basic mechanisms of bone growth, structure and metabolism, research methodology, as well as discussing the clinical management of related diseases, this book is of particular value to physicians with a special interest in bone and cartilage biology; in particular endocrinologists and pediatric endocrinologists that see patients with growth disorders, osteoporosis, osteogenesis imperfecta, and skeletal dysplasias.

Genetics of Bone Biology and Skeletal Disease

Genetics of Bone Biology and Skeletal Disease
A Book

by Rajesh V. Thakker,Michael P. Whyte,John Eisman,Takashi Igarashi

  • Publisher : Academic Press
  • Release : 2017-10-31
  • Pages : 878
  • ISBN : 0128041986
  • Language : En, Es, Fr & De
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Genetics of Bone Biology and Skeletal Disease, Second Edition, is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid and related disorders, and vitamin D and renal disorders. The first section is specifically devoted to providing an overview of bone biology and structure, joint and cartilage biology, principles of endocrine regulation of bone, and the role of neuronal regulation and energy homeostasis. The second section reviews the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, copy number variation, prospects of gene therapy, pharmacogenomics, genetic testing and counseling, as well as the generation and utilizing of mouse models. The third section details advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasias, and rarer bone disorders. The fourth section highlights the central role of the parathyroids in calcium and skeletal homeostasis by reviewing the molecular genetics of: hyperparathyroidism, hypoparathyrodism, endocrine neoplasias, and disorders of the PTH and calcium-sensing receptors. The fifth section details molecular and cellular advances across associated renal disorders such as vitamin D and rickets. Identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluation of treatments Demonstrates how the interactions between bone and joint biology, physiology, and genetics have greatly enhanced the understanding of normal bone function as well as the molecular pathogenesis of metabolic bone disorders Summarizes the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder

Bones and Cartilage

Bones and Cartilage
Skeleton Coloring Book

by Bobo's Children Activity Books

  • Publisher : Bobo's Children Activity Books
  • Release : 2016-07-06
  • Pages : 329
  • ISBN : 9781683275251
  • Language : En, Es, Fr & De
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Let's learn about the human body's skeletal system through this smart activity book. Here, you will be working with actual pictures instead of just reading texts. This means that learning becomes an experience that will create imprints in the mind. Get started on coloring! Grab a copy of this coloring book today!

High Yield Orthopaedics

High Yield Orthopaedics
A Book

by Javad Parvizi

  • Publisher : Elsevier Health Sciences
  • Release : 2010
  • Pages : 510
  • ISBN : 1416002367
  • Language : En, Es, Fr & De
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Get your hands on this concise, visual guide to orthopaedics packed with the absolutely essential facts!. --Book Jacket.

Osteoarthritis

Osteoarthritis
Progress in Basic Research and Treatment

by Qian Chen

  • Publisher : BoD – Books on Demand
  • Release : 2015-07-01
  • Pages : 274
  • ISBN : 9535121367
  • Language : En, Es, Fr & De
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The most common form of arthritis is osteoarthritis (OA), which most often affects the hip, knee, foot and hand. The degeneration of joint cartilage and changes in underlying bone and supporting tissues such as ligament leads to pain, stiffness, movement problems and activity limitations. This book, containing three major sections in OA research and therapy, is an update of the book Osteoarthritis - Diagnosis, Treatment and Surgery published by InTech in 2012. The authors are experts in the osteoarthritis field, which include biologists, bioengineers, clinicians, and health professionals. The scientific content of the book will be beneficial to patients, students, researchers, educators, physicians, and health care providers who are interested in the recent progress in osteoarthritis research and therapy.

Biophysics and Biochemistry of Cartilage by NMR and MRI

Biophysics and Biochemistry of Cartilage by NMR and MRI
A Book

by Yang Xia,Konstantin Momot

  • Publisher : Royal Society of Chemistry
  • Release : 2016-11-09
  • Pages : 731
  • ISBN : 1782623663
  • Language : En, Es, Fr & De
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This unique book describes the latest information in the fundamental understanding of the biophysics and biochemistry of articular cartilage using the state-of-the-art practices in NMR and MRI. This is the first book of its kind, written by physicists and chemists on this important tissue, whose degradation contributes to osteoarthritis and related joint diseases. Connecting the fundamental science with the clinical imaging applications, the experts Editors provide an authoritative addition to the literature. Ideal for practising physical scientists and radiologists with an interest in the fundamental science as well as instrument manufacturers and clinical researchers working with articular cartilage.

Composition and Function of the Extracellular Matrix in the Human Body

Composition and Function of the Extracellular Matrix in the Human Body
A Book

by Francesco Travascio

  • Publisher : BoD – Books on Demand
  • Release : 2016-06-15
  • Pages : 374
  • ISBN : 9535124153
  • Language : En, Es, Fr & De
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The extracellular matrix (ECM) is an ensemble of non-cellular components present within all tissues and organs of the human body. The ECM provides structural support for scaffolding cellular constituents and biochemical and biomechanical support for those events leading to tissue morphogenesis, differentiation and homeostasis. Essential components of all ECMs are water, proteins and polysaccharides. However, their composition, architecture and bioactivity greatly vary from tissue to tissue in relation to the specific role the ECM is required to assume. This book overviews the role of the ECM in different tissues and organs of the human body.

Bone and Cartilage Regeneration

Bone and Cartilage Regeneration
A Book

by Phuc Van Pham

  • Publisher : Springer
  • Release : 2017-01-24
  • Pages : 315
  • ISBN : 3319401440
  • Language : En, Es, Fr & De
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This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in bone and cartilage regeneration. Each chapter is contributed by a pre-eminent scientist in the field and covers such topics as skeletal regeneration by mesenchymal stem cells, clinical improvement of mesenchymal stem cell injection in injured cartilage and osteoarthritis, Good manufacturing practice (GMP), minimal critera of stem cells for clinical applications, future directions of the discussed therapies and much more. Bone & Cartilage Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.

Bones and Cartilage

Bones and Cartilage
Developmental and Evolutionary Skeletal Biology

by Brian K. Hall

  • Publisher : Academic Press
  • Release : 2014-12-23
  • Pages : 920
  • ISBN : 0124166857
  • Language : En, Es, Fr & De
GET BOOK

Bones and Cartilage provides the most in-depth review and synthesis assembled on the topic, across all vertebrates. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage develop in embryos and are maintained in adults, how bone is repaired when we break a leg, or regenerates when a newt grows a new limb, or a lizard a new tail. The second edition of Bones and Cartilage includes the most recent knowledge of molecular, cellular, developmental and evolutionary processes, which are integrated to outline a unified discipline of developmental and evolutionary skeletal biology. Additionally, coverage includes how the molecular and cellular aspects of bones and cartilage differ in different skeletal systems and across species, along with the latest studies and hypotheses of relationships between skeletal cells and the most recent information on coupling between osteocytes and osteoclasts All chapters have been revised and updated to include the latest research. Offers complete coverage of every aspect of bone and cartilage, with updated references and extensive illustrations Integrates development and evolution of the skeleton, as well a synthesis of differentiation, growth and patterning Treats all levels from molecular to clinical, embryos to evolution, and covers all vertebrates as well as invertebrate cartilages Includes new chapters on evolutionary skeletal biology that highlight normal variation and variability, and variation outside the norm (neomorphs, atavisms) Updates hypotheses on the origination of cartilage using new phylogenetic, cellular and genetic data Covers stem cells in embryos and adults, including mesenchymal stem cells and their use in genetic engineering of cartilage, and the concept of the stem cell niche

Junqueira's Basic Histology

Junqueira's Basic Histology
Text and Atlas

by Luiz Carlos Uchôa Junqueira,Anthony L. Mescher

  • Publisher : Unknown Publisher
  • Release : 2013-05-01
  • Pages : 544
  • ISBN : 9781259072321
  • Language : En, Es, Fr & De
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The histology text the medical field turns to first -- authoritative, concise, beautifully illustrated, and completely up-to-date More than 600 full-color illustrations For more than three decades, Junquiera's Basic Histology has been unmatched in its ability to explain the relationship between cell and tissue structure with their function in the human body. Updated to reflect the latest research in the field and enhanced with more than 600 full-color illustrations, the thirteenh edition of Junqueira's represents the most comprehensive and modern approach to understanding medical histology available anywhere.

Cartilage Repair and Regeneration

Cartilage Repair and Regeneration
A Book

by Alessandro Rozim Zorzi,João Batista de Miranda

  • Publisher : BoD – Books on Demand
  • Release : 2018-02-14
  • Pages : 228
  • ISBN : 9535137883
  • Language : En, Es, Fr & De
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This work is the result of a partnership that began in 2011, when I received for the first time the invitation to be the scientific editor of a book on bone grafting, by the still little publisher known as InTech. Now six years later, InTech has grown and thrived. My respect and warm approval for the quality of the publisher's work only increased. The hyaline cartilage is a tissue that challenges tissue engineering and regenerative medicine because of its avascular nature. In the 11 chapters of this book, the reader will find texts written by researchers working on advanced topics related to basic laboratory research, as well as excellent reviews on the clinical use of currently available therapies.

Physiology And Pathology

Physiology And Pathology
A Book

by Geoffrey Bourne

  • Publisher : Elsevier
  • Release : 2012-12-02
  • Pages : 424
  • ISBN : 0323161758
  • Language : En, Es, Fr & De
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The Biochemistry and Physiology of Bone, Second Edition: Volume II: Physiology and Pathology investigates the physiological and pathological aspects of bone, including the blood vessels that nourish the bones; the mechanisms of bone formation, growth, repair, and transplantation; and the role of hormones and vitamins in the formation and maintenance of bone. It explores the circulation of bone, the pathological calcification and radiation effects on bone, the metabolism of growth hormones and skeletal tissue, enamel and dentin matrix glycoproteins, and the role of calcitonin in homeostasis. Organized into nine chapters, this edition begins with an overview of the circulation of bone, including the overall blood supply of a long bone. It discusses the phosphatase and its histological distribution in mature and developing bone, the presence of glycoproteins in the organic matrix of enamel and dentin, and human dwarfism and human growth hormone replacement therapy. It explains the roles of vitamins and the effects of calcitonin and vitamin deficiency on bone growth and development. The book concludes with a chapter on the chemistry of calcification and some types of abnormal calcification. This book is a valuable resource for biochemists, cell biologists, physiologists, anatomists, orthopedists, pathologists, clinicians, biomedical engineers, graduate students, professors, and others interested in the physiology and pathology of bone.

Skeletal Function and Form

Skeletal Function and Form
Mechanobiology of Skeletal Development, Aging, and Regeneration

by Dennis R. Carter,Gary S. Beaupré

  • Publisher : Cambridge University Press
  • Release : 2007-08-25
  • Pages : 332
  • ISBN : 9780521714754
  • Language : En, Es, Fr & De
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The intimate relationship between form and function inherent in the design of animals is perhaps nowhere more evident than in the musculoskeletal system. In the bones, cartilage, tendons, ligaments, and muscles of all vertebrates there is a graceful and efficient physical order. This book is about how function determines form. It addresses the role of mechanical factors in the development, adaptation, maintenance, ageing and repair of skeletal tissues. The authors refer to this process as mechanobiology and develop their theme within an evolutionary framework. They show how the normal development of skeletal tissues is influenced by mechanical stimulation beginning in the embryo and continuing throughout life into old age. They also show how degenerative disorders such as arthritis and osteoporosis are regulated by the same mechanical processes that influence development and growth. Skeletal Function and Form bridges important gaps among disciplines, providing a common ground for understanding, and will appeal to a wide audience of bioengineers, zoologists, anthropologists, palaeontologists and orthopaedists.