Exam Prep for: Advances in Cell and Molecular Diagnostics

Exam Prep for: Advances in Cell and Molecular Diagnostics
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2021
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Advances in Cell and Molecular Diagnostics

Advances in Cell and Molecular Diagnostics
A Book

by Pongali Raghavendra,Thammineni Pullaiah

  • Publisher : Academic Press
  • Release : 2018-01-10
  • Pages : 298
  • ISBN : 0128136804
  • Language : En, Es, Fr & De
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Advances in Cell and Molecular Diagnostics brings the scientific advances in the translation and validation of cellular and molecular discoveries in medicine into the clinical diagnostic setting. It enumerates the description and application of technological advances in the field of cellular and molecular diagnostic medicine, providing an overview of specialized fields, such as biomarker, genetic marker, screening, DNA-profiling, NGS, cytogenetics, transcriptome, cancer biomarkers, prostate specific antigen, and biomarker toxicologies. In addition, it presents novel discoveries and clinical pathologic correlations, including studies in oncology, infectious diseases, inherited diseases, predisposition to disease, and the description or polymorphisms linked to disease states. This book is a valuable resource for oncologists, practitioners and several members of the biomedical field who are interested in understanding how to apply cutting-edge technologies into diagnostics and healthcare. Encompasses the current scientific advances in the translation and validation of cellular and molecular discoveries into the clinical diagnostic setting Explains the application of cellular and molecular diagnostics methodologies in clinical trials Focuses on translating preclinical tests to the bedside in order to help readers apply the most recent technologies to healthcare

Advances in Cell and Molecular Diagnostics

Advances in Cell and Molecular Diagnostics
A Book

by Pongali Raghavendra,Thammineni Pullaiah

  • Publisher : Academic Press
  • Release : 2018-01-10
  • Pages : 298
  • ISBN : 0128136804
  • Language : En, Es, Fr & De
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Advances in Cell and Molecular Diagnostics brings the scientific advances in the translation and validation of cellular and molecular discoveries in medicine into the clinical diagnostic setting. It enumerates the description and application of technological advances in the field of cellular and molecular diagnostic medicine, providing an overview of specialized fields, such as biomarker, genetic marker, screening, DNA-profiling, NGS, cytogenetics, transcriptome, cancer biomarkers, prostate specific antigen, and biomarker toxicologies. In addition, it presents novel discoveries and clinical pathologic correlations, including studies in oncology, infectious diseases, inherited diseases, predisposition to disease, and the description or polymorphisms linked to disease states. This book is a valuable resource for oncologists, practitioners and several members of the biomedical field who are interested in understanding how to apply cutting-edge technologies into diagnostics and healthcare. Encompasses the current scientific advances in the translation and validation of cellular and molecular discoveries into the clinical diagnostic setting Explains the application of cellular and molecular diagnostics methodologies in clinical trials Focuses on translating preclinical tests to the bedside in order to help readers apply the most recent technologies to healthcare

Advances in Molecular Pathology

Advances in Molecular Pathology
A Book

by Gregory J. Tsongalis

  • Publisher : Elsevier
  • Release : 2018-11-28
  • Pages : 329
  • ISBN : 9780323639651
  • Language : En, Es, Fr & De
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This inaugural issue of Advances in Molecular Pathology will provide a comprehensive review of the most current practices, trends, and developments in the field of Molecular Pathology. Publishing on an annual basis, the volume will be divided into 7 sections: Genetics, Hematopathology, Infectious Disease, Pharmacogenomics, Informatics, Solid tumors, and Identity/HLA. Led by Dr. Gregory Tsongalis of Dartmouth University, a team of experienced pathologists from institutions across the country oversee annual topic and expert author selection. Topics discussed in this volume include, but are not limited to: whole genome sequencing in critically ill children, bioinformatics in clinical genomic sequencing, comprehensive monitoring of patients with chronic myeloid leukemia, genetic biomarkers in the biology and clinical workup of chronic lymphocytic leukemia, metagenomics in infectious disease, point of care molecular testing, pharmacogenomics in oncology, clinical uses of panel testing vs. single gene testing, large scale data sharing initiatives in genomic oncology, clinical NGS assays for solid tumors emerging concepts in liquid biopsy the cell line and tissue misidentification problem, and cell line detective work.

Recent Advances in Cell Biology of Acute Leukemia

Recent Advances in Cell Biology of Acute Leukemia
Impact on Clinical Diagnosis and Therapy

by Wolf-Dieter Ludwig,Eckhard Thiel

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 407
  • ISBN : 3642848958
  • Language : En, Es, Fr & De
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The development of new techniques such as immuno phenotyping, cytogenetic investigations and, more recently, molecular studies has considerably increased our diagnostic repertoire and broadened our ideas about the biology of acute leukemias. While immunophenotyping with mono clonal antibodies has yielded increased diagnostic precision and made it possible to develop a highly reproducible classification of acute leukemias based on cell-biological features, further insights have been gained into the patho genetic mechanisms involved in leukemogenesis by means of cytogenetic detection of acquired structural chromosomal abnormalities. Analysis of the leukemia-associated chromo somal breakpoints using molecular techniques can now pinpoint many genomic sites essential for normal develop ment and maturation of hematopoietic cells but functionally disrupted in leukemic cells. The main goal of the international workshop that we held in Berlin with a select group of scientists and clinicians involved in leukemia research was to describe the state of the art and new developments in the immunologic, cytogenetic, and molecular characterization of acute leukemias and to discuss the clinical importance of cell biological features. After introductory survey lectures dealing with the immunological and molecular-biological characteristics of normal vs. malignant lymphatic and myeloid progenitor cells, the workshop centered on con tributions characterizing the immunophenotype and both numerical and structural chromosomal abnormalities in acute leukemias.

Molecular Diagnostics

Molecular Diagnostics
Techniques and Applications for the Clinical Laboratory

by Wayne W. Grody,Robert M. Nakamura,Frederick L. Kiechle,Charles Strom

  • Publisher : Academic Press
  • Release : 2009-11-06
  • Pages : 736
  • ISBN : 9780080919041
  • Language : En, Es, Fr & De
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Advances in genomic and proteomic profiling of disease have transformed the field of molecular diagnostics, thus leading the way for a major revolution in clinical practice. While the range of tests for disease detection and staging is rapidly expanding, many physicians lack the knowledge required to determine which tests to order and how to interpret results. Molecular Diagnostics provides a complete guide to the use and interpretation of molecular testing in the clinical arena. No other available resource offers this emphasis, comprehensive scope, and practical utility in the clinical setting. Serves as the definitivereference for molecular pathologists worldwide Covers a variety of molecular techniques including next generation sequencing, tumor somatic cell genotyping, infectious and genetic disease tecting, and pharmacogenetics Discusses in the detail issues concerning quality assurance, regulation, ethics, and future directions for the science

Molecular Diagnostics

Molecular Diagnostics
A Book

by George P. Patrinos,Wilhelm Ansorge,Phillip B. Danielson

  • Publisher : Academic Press
  • Release : 2016-10-27
  • Pages : 520
  • ISBN : 0128029889
  • Language : En, Es, Fr & De
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Molecular Diagnostics, Third Edition, focuses on the technologies and applications that professionals need to work in, develop, and manage a clinical diagnostic laboratory. Each chapter contains an expert introduction to each subject that is next to technical details and many applications for molecular genetic testing that can be found in comprehensive reference lists at the end of each chapter. Contents are divided into three parts, technologies, application of those technologies, and related issues. The first part is dedicated to the battery of the most widely used molecular pathology techniques. New chapters have been added, including the various new technologies involved in next-generation sequencing (mutation detection, gene expression, etc.), mass spectrometry, and protein-specific methodologies. All revised chapters have been completely updated, to include not only technology innovations, but also novel diagnostic applications. As with previous editions, each of the chapters in this section includes a brief description of the technique followed by examples from the area of expertise from the selected contributor. The second part of the book attempts to integrate previously analyzed technologies into the different aspects of molecular diagnostics, such as identification of genetically modified organisms, stem cells, pharmacogenomics, modern forensic science, molecular microbiology, and genetic diagnosis. Part three focuses on various everyday issues in a diagnostic laboratory, from genetic counseling and related ethical and psychological issues, to safety and quality management. Presents a comprehensive account of all new technologies and applications used in clinical diagnostic laboratories Explores a wide range of molecular-based tests that are available to assess DNA variation and changes in gene expression Offers clear translational presentations by the top molecular pathologists, clinical chemists, and molecular geneticists in the field

Advances in Molecular Pathology, E-Book

Advances in Molecular Pathology, E-Book
A Book

by Gregory J. Tsongalis

  • Publisher : Elsevier Health Sciences
  • Release : 2020-11-07
  • Pages : 240
  • ISBN : 032372227X
  • Language : En, Es, Fr & De
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This issue of Advances in Molecular Pathology will provide a comprehensive review of the most current practices, trends, and developments in the field of Molecular Pathology. Publishing on an annual basis, the volume will be divided into 7 sections: Genetics, Hematopathology, Infectious Disease, Pharmacogenomics, Informatics, Solid tumors, and Identity/HLA. Led by Dr. Gregory Tsongalis of Dartmouth University, a team of experienced pathologists from institutions across the country oversee annual topic and expert author selection.

Clinical Molecular Medicine

Clinical Molecular Medicine
Principles and Practice

by Dhavendra Kumar

  • Publisher : Academic Press
  • Release : 2019-11-30
  • Pages : 606
  • ISBN : 0128094427
  • Language : En, Es, Fr & De
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Clinical Molecular Medicine: Principles and Practice presents the latest scientific advances in molecular and cellular biology, including the development of new and effective drug and biological therapies and diagnostic methods. The book provides medical and biomedical students and researchers with a clear and clinically relevant understanding on the molecular basis of human disease. With an increased focus on new practice concepts, such as stratified, personalized and precision medicine, this book is a valuable and much-needed resource that unites the core principles of molecular biology with the latest and most promising genomic advances. Illustrates the fundamental principles and therapeutic applications of molecular and cellular biology Offers a clinically focused account of molecular heterogeneity Includes comprehensive coverage of many different disorders, including growth and development, cardiovascular, metabolic, skin, blood, digestive, inflammatory, neuropsychiatric disorders, and many more

Globalization, Biosecurity, and the Future of the Life Sciences

Globalization, Biosecurity, and the Future of the Life Sciences
A Book

by National Research Council,Institute of Medicine,Board on Global Health,Policy and Global Affairs,Development, Security, and Cooperation,Committee on Advances in Technology and the Prevention of Their Application to Next Generation Biowarfare Threats

  • Publisher : National Academies Press
  • Release : 2006-06-07
  • Pages : 316
  • ISBN : 9780309164757
  • Language : En, Es, Fr & De
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Biomedical advances have made it possible to identify and manipulate features of living organisms in useful ways--leading to improvements in public health, agriculture, and other areas. The globalization of scientific and technical expertise also means that many scientists and other individuals around the world are generating breakthroughs in the life sciences and related technologies. The risks posed by bioterrorism and the proliferation of biological weapons capabilities have increased concern about how the rapid advances in genetic engineering and biotechnology could enable the production of biological weapons with unique and unpredictable characteristics. Globalization, Biosecurity, and the Future of Life Sciences examines current trends and future objectives of research in public health, life sciences, and biomedical science that contain applications relevant to developments in biological weapons 5 to 10 years into the future and ways to anticipate, identify, and mitigate these dangers.

Molecular Diagnostics and Treatment of Pancreatic Cancer

Molecular Diagnostics and Treatment of Pancreatic Cancer
Systems and Network Biology Approaches

by Asfar Azmi

  • Publisher : Elsevier
  • Release : 2014-04-14
  • Pages : 458
  • ISBN : 0124079466
  • Language : En, Es, Fr & De
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Molecular Diagnostics and Treatment of Pancreatic Cancer describes the different emerging applications of systems biology and how it is shaping modern pancreatic cancer research. This book begins by introducing the current state of the art knowledge, trends in diagnostics, progress in disease model systems as well as new treatment and palliative care strategies in pancreatic cancer. Specific sections are dedicated to enlighten the readers to newer discoveries that have emerged from gene expression profiling, proteomics, metabolomics and systems level analyses of pancreatic cancer datasets. First of a kind and novel network strategies to understand oncogenic Kras signaling in pancreatic tumors are presented. The attempts to computationally model and prioritize microRNAs that cause pancreatic cancer resistance are also highlighted. Addressing this important area, Molecular Diagnostics and Treatment of Pancreatic Cancer provides insights into important network evaluation methodologies related to pancreatic cancer related microRNAs targetome. There are dedicated chapters on critical aspects of the evolving yet controversial field of pancreatic cancer stems cells. The work concludes by discussing the applications of network sciences in pancreatic cancer drug discovery and clinical trial design. Encompasses discussion of innovative tools including expression signatures in cell lines, 3D models, animal xenograft models, primary models and patient derived samples, aiding subversion of traditional biology paradigms, and enhancing comprehension across conventional length and temporal scales Coverage includes novel applications in targeted drugs, polypharmacology, network pharmacology and other related drug development arenas – helping researchers in pancreatic cancer drug discovery Summarizes many relevant computational and clinical references from fast-evolving literature Comprehensive glossary helps newer readers understand technical terms and specialized nomenclature

Advances in Cancer Research

Advances in Cancer Research
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2019-03-15
  • Pages : 312
  • ISBN : 0128171537
  • Language : En, Es, Fr & De
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Advances in Cancer Research, Volume 142, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research. Provides information on cancer research Offers outstanding and original reviews on a range of cancer research topics Serves as an indispensable reference for researchers and students alike

Advances in Microbial Physiology

Advances in Microbial Physiology
A Book

by Robert K. Poole

  • Publisher : Academic Press
  • Release : 2020-05-22
  • Pages : 196
  • ISBN : 0128207469
  • Language : En, Es, Fr & De
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Advances in Microbial Physiology, Volume 76, the latest release in this ongoing series, continues the long tradition of topical, important, cutting-edge reviews in microbiology. The updated release contains updates in the field, with comprehensive chapters covering Bacteria respiration during infection, Spironucleus vortens: functional imaging of a model aerotolerant flagellated protist, In situ Absorbance Measurements: a New Means to Study Respiratory Electron Transfer in Chemolithotrophic microorganisms, Microbubbles in microbiology, Bacterial catabolism of s-triazine herbicides: biochemistry, evolution and application, and more. Contains contributions from leading authorities in microbial physiology Informs and updates on all the latest developments in the field of microbial physiology

The Molecular Basis of Neurosurgical Disease

The Molecular Basis of Neurosurgical Disease
A Book

by Corey Raffel,Griffith R. Harsh

  • Publisher : Lippincott Williams & Wilkins
  • Release : 1996
  • Pages : 393
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Molecular strategies & techniques basic concepts of gene therapy molecular neuro-oncology etc.

Principles and Applications of Molecular Diagnostics

Principles and Applications of Molecular Diagnostics
A Book

by Nader Rifai,A. Rita Horvath,Carl T. Wittwer,Jason Park

  • Publisher : Elsevier
  • Release : 2018-06-13
  • Pages : 422
  • ISBN : 0128160624
  • Language : En, Es, Fr & De
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Principles and Applications of Molecular Diagnostics serves as a comprehensive guide for clinical laboratory professionals applying molecular technology to clinical diagnosis. The first half of the book covers principles and analytical concepts in molecular diagnostics such as genomes and variants, nucleic acids isolation and amplification methods, and measurement techniques, circulating tumor cells, and plasma DNA; the second half presents clinical applications of molecular diagnostics in genetic disease, infectious disease, hematopoietic malignancies, solid tumors, prenatal diagnosis, pharmacogenetics, and identity testing. A thorough yet succinct guide to using molecular testing technology, Principles and Applications of Molecular Diagnostics is an essential resource for laboratory professionals, biologists, chemists, pharmaceutical and biotech researchers, and manufacturers of molecular diagnostics kits and instruments. Explains the principles and tools of molecular biology Describes standard and state-of-the-art molecular techniques for obtaining qualitative and quantitative results Provides a detailed description of current molecular applications used to solve diagnostics tasks

Advances in Clinical Chemistry

Advances in Clinical Chemistry
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2019-07-30
  • Pages : 219
  • ISBN : 0128174714
  • Language : En, Es, Fr & De
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Advances in Clinical Chemistry, Volume 91, the latest release in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, providing the benchmark for novel analytical approaches in the clinical laboratory. Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science Authored by world renowned clinical laboratory scientists, physicians and research scientists Presents the international benchmark for novel analytical approaches in the clinical laboratory

Molecular Pathology

Molecular Pathology
The Molecular Basis of Human Disease

by William B. Coleman,Gregory J. Tsongalis

  • Publisher : Academic Press
  • Release : 2017-11-09
  • Pages : 802
  • ISBN : 0128027878
  • Language : En, Es, Fr & De
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As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

Molecular Diagnostics: Promises and Possibilities

Molecular Diagnostics: Promises and Possibilities
A Book

by Mousumi Debnath,Godavarthi B.K.S. Prasad,Prakash S. Bisen

  • Publisher : Springer Science & Business Media
  • Release : 2010-01-29
  • Pages : 520
  • ISBN : 9789048132614
  • Language : En, Es, Fr & De
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A rapid development in diverse areas of molecular biology and genetic engineering resulted in emergence of variety of tools. These tools are not only applicable to basic researches being carried out world over, but also exploited for precise detection of abnormal conditions in plants, animals and human body. Although a basic researcher is well versed with few techniques used by him/her in the laboratory, they may not be well acquainted with methodologies, which can be used to work out some of their own research problems. The picture is more blurred when the molecular diagnostic tools are to be used by physicians, scientists and technicians working in diagnostic laboratories in hospitals, industry and academic institutions. Since many of them are not trained in basics of these methods, they come across several gray areas in understanding of these tools. The accurate application of molecular diagnostic tools demands in depth understanding of the methodology for precise detection of the abnormal condition of living body. To meet the requirements of a good book on molecular diagnostics of students, physicians, scientists working in agricultural, veterinary, medical and pharmaceutical sciences, it needs to expose the reader lucidly to: Give basic science behind commonly used tools in diagnostics Expose the readers to detailed applications of these tools and Make them aware the availability of such diagnostic tools The book will attract additional audience of pathologists, medical microbiologists, pharmaceutical sciences, agricultural scientists and veterinary doctors if the following topics are incorporated at appropriate places in Unit II or separately as a part of Unit-III in the book. Molecular diagnosis of diseases in agricultural crops Molecular diagnosis of veterinary diseases. Molecular epidemiology, which helps to differentiate various epidemic strains and sources of disease outbreaks. Even in different units of the same hospital, the infections could be by different strains of the same species and the information becomes valuable for infection control strategies. Drug resistance is a growing problem for bacterial, fungal and parasitic microbes and the molecular biology tools can help to detect the drug resistance genes without the cultivation and in vitro sensitivity testing. Molecular diagnostics offers faster help in the selection of the proper antibiotic for the treatment of tuberculosis, which is a major problem of the in the developing world. The conventional culture and drug sensitivity testing of tuberculosis bacilli is laborious and time consuming, whereas molecular diagnosis offers rapid drug resistant gene detection even from direct clinical samples. The same approach for HIV, malaria and many more diseases needs to be considered. Molecular diagnostics in the detection of diseases during foetal life is an upcoming area in the foetal medicine in case of genetic abnormalities and infectious like TORCH complex etc. The book will be equally useful to students, scientists and professionals working in the field of molecular diagnostics.

Molecular Biology

Molecular Biology
Different Facets

by Anjali Priyadarshini,Prerna Pandey

  • Publisher : CRC Press
  • Release : 2018-06-27
  • Pages : 318
  • ISBN : 1351582615
  • Language : En, Es, Fr & De
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This volume provides a comprehensive description of the basic tenets of molecular biology, from mechanisms to its elaborate role in gene regulation. The initial sections cover the history of genetics and molecular biology. The book then goes on to highlight the significance of molecular approaches for all biological processes in both simple and complex cells. The volume incorporates the most recent research from this ever-evolving field. The authors have described experimental approaches wherever necessary to present evidence that has led to the development of important concepts and significant advances in molecular biology.

Advances in Optical Imaging and Photon Migration

Advances in Optical Imaging and Photon Migration
From the Topical Meeting [sic] Advances in Optical Imaging and Photon Migration, March 8-11, 1998, Orlando, Florida

by James G. Fujimoto,Michael S. Patterson

  • Publisher : Optical Society of Amer
  • Release : 1998
  • Pages : 478
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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