Handbook of Magnetic Resonance Spectroscopy In Vivo

Handbook of Magnetic Resonance Spectroscopy In Vivo
MRS Theory, Practice and Applications

by Paul A. Bottomley,John R. Griffiths

  • Publisher : John Wiley & Sons
  • Release : 2016-12-19
  • Pages : 1232
  • ISBN : 1118997662
  • Language : En, Es, Fr & De
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This handbook covers the entire field of magnetic resonance spectroscopy (MRS), a unique method that allows the non-invasive identification, quantification and spatial mapping of metabolites in living organisms–including animal models and patients. Comprised of three parts: Methodology covers basic MRS theory, methodology for acquiring, quantifying spectra, and spatially localizing spectra, and equipment essentials, as well as vital ancillary issues such as motion suppression and physiological monitoring. Applications focuses on MRS applications, both in animal models of disease and in human studies of normal physiology and disease, including cancer, neurological disease, cardiac and muscle metabolism, and obesity. Reference includes useful appendices and look up tables of relative MRS signal-to-noise ratios, typical tissue concentrations, structures of common metabolites, and useful formulae. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of Magnetic Resonance) publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this handbook and the complete content of eMagRes at your fingertips! Visit the eMagRes Homepage

A Handbook of Nuclear Magnetic Resonance

A Handbook of Nuclear Magnetic Resonance
A Book

by Ray Freeman

  • Publisher : Longman Group United Kingdom
  • Release : 1997
  • Pages : 344
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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This new edition has been thoroughly revised to bring the handbook up-to-date.

Handbook of Magnetic Resonance Spectroscopy In Vivo

Handbook of Magnetic Resonance Spectroscopy In Vivo
MRS Theory, Practice and Applications

by Paul A. Bottomley,John R. Griffiths

  • Publisher : John Wiley & Sons
  • Release : 2016-10-19
  • Pages : 1232
  • ISBN : 1118997697
  • Language : En, Es, Fr & De
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This handbook covers the entire field of magnetic resonance spectroscopy (MRS), a unique method that allows the non-invasive identification, quantification and spatial mapping of metabolites in living organisms–including animal models and patients. Comprised of three parts: Methodology covers basic MRS theory, methodology for acquiring, quantifying spectra, and spatially localizing spectra, and equipment essentials, as well as vital ancillary issues such as motion suppression and physiological monitoring. Applications focuses on MRS applications, both in animal models of disease and in human studies of normal physiology and disease, including cancer, neurological disease, cardiac and muscle metabolism, and obesity. Reference includes useful appendices and look up tables of relative MRS signal-to-noise ratios, typical tissue concentrations, structures of common metabolites, and useful formulae. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of Magnetic Resonance) publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this handbook and the complete content of eMagRes at your fingertips! Visit the eMagRes Homepage

Handbook of Tritium NMR Spectroscopy and Applications

Handbook of Tritium NMR Spectroscopy and Applications
A Book

by Eustace Anthony Evans

  • Publisher : John Wiley & Sons
  • Release : 1985
  • Pages : 249
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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This book is primarily a handbook for those scientists interested in using tritium NMR spectroscopy. It covers the development and use of the technique, which is the only non- destructive method available for the routine determination of labelling patterns in tritium labelled compounds, essential tools for research in the life sciences. The book highlights the uses of the technique not only for determining the positions of labels but also in understanding catalysed hydrogen isotope exchange reactions, the function and mechanism of action of catalysts, reaction mechanisms and isotope effects.

Dynamic Hyperpolarized Nuclear Magnetic Resonance

Dynamic Hyperpolarized Nuclear Magnetic Resonance
A Book

by Thomas Jue,Dirk Mayer

  • Publisher : Springer
  • Release : 2021-06-24
  • Pages : 279
  • ISBN : 9783030550417
  • Language : En, Es, Fr & De
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This is the first book in the series to focus on dynamic hyperpolarized nuclear magnetic resonance, a burgeoning topic in biophysics. The volume follows the format and style of the Handbook of Modern Biophysics series and expands on topics already discussed in previous volumes. It builds a theoretical and experimental framework for students and researchers who wish to investigate the biophysics and biomedical application of dynamic hyperpolarized NMR. All contributors are internationally recognized experts, lead the dynamic hyperpolarized NMR field, and have first-hand knowledge of the chapter material. The book covers the following topics: Hyperpolarization by dissolution Dynamic Nuclear Polarization Design considerations for implementing a hyperpolarizer Chemical Shift Imaging with Dynamic Hyperpolarized NMR Signal Sampling Strategies in Dynamic Hyperpolarized NMR Kinetic Modeling of Enzymatic Reactions in Analyzing Hyperpolarized NMR Data Using Hyperpolarized NMR to Understand Biochemistry from Cells to Humans Innovating Metabolic Biomarkers for Hyperpolarized NMR New Insights into Metabolic Regulation from Hyperpolarized 13C MRS/MRI Studies Novel Views on Heart Function from Dynamic Hyperpolarized NMR Insights on Lactate Metabolism in Skeletal Muscle based on 13C Dynamic Nuclear Polarization Studies About the Editors Dirk Mayer is Professor of Diagnostic Radiology and Nuclear Medicine at the University of Maryland and is the Director of Metabolic Imaging. He is a recognized expert on dynamic nuclear polarization (DNP) MRI-based imaging techniques and has optimized acquisition and reconstruction techniques, has constructed kinetic modeling for quantitative analysis, and has developing new probes. Thomas Jue is Professor of Biochemistry and Molecular Medicine at the University of California Davis. He is an internationally recognized expert in developing and applying magnetic resonance techniques to study animal as well as human physiology in vivo. He served as a Chair of the Biophysics Graduate Group Program at UC Davis, where he started to redesign a graduate curriculum that balances physical science/mathematics formalism and biomedical perspective in order to promote interest at the interface of physical science, engineering, mathematics, biology, and medicine. The Handbook of Modern Biophysics represents an aspect of that effort.

Solid State NMR Studies of Biopolymers

Solid State NMR Studies of Biopolymers
A Book

by Anne E. McDermott,Tatyana Polenova

  • Publisher : John Wiley & Sons
  • Release : 2012-12-19
  • Pages : 592
  • ISBN : 1118588886
  • Language : En, Es, Fr & De
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The content of this volume has been added toeMagRes (formerly Encyclopedia of MagneticResonance) - the ahref="http://onlinelibrary.wiley.com/book/10.1002/9780470034590/homepage/rf_coils_virtual_issue.htm?cm=on-chem&cs=chem-analytic&cu=sitename-ln&cd=sitename-In-MRIgroup-VI" target="_blank"ultimate online resource for NMR and MRI/a. The field of solid state NMR of biological samples [ssNMR] hasblossomed in the past 5-10 years, and a cohesive overview of thetechnology is needed for new practitioners in industry andacademia. This title provides an overview of Solid State NMRmethods for studying structure dynamics and ligand-binding inbiopolymers, and offers an overview of RF pulse sequences forvarious applications, including not only a systematic catalog butalso a discussion of theoretical tools for analysis of pulsesequences. Practical examples of biochemical applications areincluded, along with a detailed discussion of the many aspects ofsample preparation and handling that make spectroscopy on solidproteins successful. About EMR Handbooks / eMagResHandbooks The Encyclopedia of Magnetic Resonance (up to 2012) andeMagRes (from 2013 onward) publish a wide range of onlinearticles on all aspects of magnetic resonance in physics,chemistry, biology and medicine. The existence of this large numberof articles, written by experts in various fields, is enabling thepublication of a series of EMR Handbooks / eMagResHandbooks on specific areas of NMR and MRI. Thechapters of each of these handbooks will comprise a carefullychosen selection of articles from eMagRes. In consultationwith the eMagRes Editorial Board, the EMRHandbooks / eMagRes Handbooks are coherentlyplanned in advance by specially-selected Editors, and new articlesare written (together with updates of some already existingarticles) to give appropriate complete coverage. The handbooks areintended to be of value and interest to research students,postdoctoral fellows and other researchers learning about thescientific area in question and undertaking relevant experiments,whether in academia or industry. Have the content of this Handbook and the complete content ofeMagRes at your fingertips! Visit: ahref="http://www.wileyonlinelibrary.com/ref/eMagRes"www.wileyonlinelibrary.com/ref/eMagRes/a View other eMagRes publications ahref="http://onlinelibrary.wiley.com/book/10.1002/9780470034590/homepage/emagres_publications.htm" target="_blank"here/a

Handbook of High Field Dynamic Nuclear Polarization

Handbook of High Field Dynamic Nuclear Polarization
A Book

by Vladimir K. Michaelis,Robert G. Griffin,Björn Corzilius,Shimon Vega

  • Publisher : John Wiley & Sons
  • Release : 2020-01-03
  • Pages : 472
  • ISBN : 1119441668
  • Language : En, Es, Fr & De
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Addresses Dynamic Nuclear Polarization (DNP) as a technique for sensitivity-enhancement in solid-state NMR spectroscopy This comprehensive handbook is a compendium of the current state-of-the art of high field Dynamic Nuclear Polarization—from long-proven, early developments, up to today’s hot topics. It covers all the relevant subjects that have made a direct or indirect contribution toward advancing this field, and focuses on topics such as: the theory behind the effects seen within DNP; instrumentation required for carrying out DNP; and specific applications of DNP including protein monitoring, catalysis, nanoparticles, biological and clinical studies. Development and application of techniques that have indirectly contributed to advancing MAS DNP NMR, such as DNP experiments on static solids within microwave resonant structures, and high-field EPR, are also examined. Handbook of High Field Dynamic Nuclear Polarization is presented in three sections—Theoretical Aspects, DNP Development (instrumentation / radical / sample), and DNP NMR Applications. The first section offers chapters on; solid and cross effect DNP; thermal mixing; Overhauser; and dissolution DNP. The second looks at: microwave technology, gyrotron, and IOE; homebuilt and commercial DNP spectrometers; and glassing vs. solvent-free DNP. The final section provides information on; amyloid, membrane, and nanocrystalline proteins; metals, and surface enhanced DNP; pharmaceuticals; nanoparticles; and much more. Covers one of the biggest developing fields in magnetic resonance Relevant to students, academics, and industry within the physical, materials, medical, and biochemical sciences An excellent starting point and point-of-reference for researchers in the field Edited by a widely respected team with contributions from key researchers in the NMR community Part of the eMagRes Handbook Series Handbook of High Field Dynamic Nuclear Polarization is an ideal reference for all researchers and graduate students involved in this complex, interdisciplinary field. About eMagRes Handbooks eMagRes publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this Handbook and the complete content of eMagRes at your fingertips! Visit: www.wileyonlinelibrary.com/ref/eMagRes

NMR of Quadrupolar Nuclei in Solid Materials

NMR of Quadrupolar Nuclei in Solid Materials
A Book

by Roderick E. Wasylishen,Sharon E. Ashbrook,Stephen Wimperis

  • Publisher : John Wiley & Sons
  • Release : 2012-12-19
  • Pages : 584
  • ISBN : 1118588843
  • Language : En, Es, Fr & De
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The content of this volume has been added to eMagRes (formerly Encyclopedia of Magnetic Resonance) - the ultimate online resource for NMR and MRI. Over the past 20 years technical developments in superconducting magnet technology and instrumentation have increased the potential of NMR spectroscopy so that it is now possible to study a wide range of solid materials. In addition, one can probe the nuclear environments of many other additional atoms that possess the property of spin. In particular, it is possible to carry out NMR experiments on isotopes that have nuclear spin greater that 1⁄2 (i.e. quadrupolar nuclei). Since more that two-thirds of all NMR active isotopes are quadrupolar nuclei, applications of NMR spectroscopy with quadrupolar nuclei are increasing rapidly. The purpose of this handbook is to provide under a single cover the fundamental principles, techniques and applications of quadrupolar NMR as it pertains to solid materials. Each chapter has been prepared by an expert who has made significant contributions to out understanding and appreciation of the importance of NMR studies of quadrupolar nuclei in solids. The text is divided into three sections: The first provides the reader with the background necessary to appreciate the challenges in acquiring and interpreting NMR spectra of quadrupolar neclei in solids. The second presents cutting-edge techniques and methodology for employing these techniques to investigate quadrupolar nuclei in solids. The final section explores applications of solid-state NMR studies of solids ranging from investigations of dynamics, characterizations of biological samples, organic and inorganic materials, porous materials, glasses, catalysts, semiconductors and high-temperature superconductors. About EMR Handbooks / eMagRes Handbooks The Encyclopedia of Magnetic Resonance (up to 2012) and eMagRes (from 2013 onward) publish a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of EMR Handbooks / eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of articles from eMagRes. In consultation with the eMagRes Editorial Board, the EMR Handbooks / eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written (together with updates of some already existing articles) to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this Handbook and the complete content of eMagRes at your fingertips! Visit: www.wileyonlinelibrary.com/ref/eMagRes View other eMagRes publications here

Spin Resonance Spectroscopy

Spin Resonance Spectroscopy
Principles and applications

by Chandran Karunakaran

  • Publisher : Elsevier
  • Release : 2018-01-02
  • Pages : 378
  • ISBN : 012813609X
  • Language : En, Es, Fr & De
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Spin Resonance Spectroscopy: Principles and Applications presents the principles, recent advancements and applications of nuclear magnetic resonance (NMR) and electron paramagnetic resonance (EPR) in a single multi-disciplinary reference. Spin resonance spectroscopic techniques through NMR and EPR are widely used by chemists, physicists, biologists and medicinal chemists. This book addresses the need for new spin resonance spectroscopy content while also presenting the principles, recent advancements and applications of NMR and EPR simultaneously. Ideal for researchers and students alike, the book provides a single source of NMR and EPR applications using a dynamic, holistic and multi-disciplinary approach. Presents a highly interdisciplinary approach by including NMR and EPR applications in chemistry, physics, biology and biotechnology Addresses both NMR and EPR, making its concepts and applications implementable in multiple resonance environments and core scientific disciplines Features a broad range of methods, examples and illustrations for both NMR and EPR to aid in retention and underscore key concepts

Handbook of Molecular Spectroscopy

Handbook of Molecular Spectroscopy
A Book

by D. N. Sathyanarayana

  • Publisher : Unknown Publisher
  • Release : 2015-12
  • Pages : 616
  • ISBN : 9789384588250
  • Language : En, Es, Fr & De
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Provides a straightforward introduction to the spectroscopy of polyatomic inorganic and organic molecules. Following a general introduction to the subject, each chapter lays down the essential group theory and atomic spectroscopy required to understand molecular spectroscopy. Chapters describe the various branches of spectroscopy, magnetic resonance, Mossbauer and X-ray absorption spectroscopy.

RF Coils for MRI

RF Coils for MRI
A Book

by J. Thomas Vaughan,John R. Griffiths

  • Publisher : John Wiley & Sons
  • Release : 2012-12-19
  • Pages : 456
  • ISBN : 1118590457
  • Language : En, Es, Fr & De
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The content of this volume has been added toeMagRes (formerly Encyclopedia of MagneticResonance) - the ahref="http://onlinelibrary.wiley.com/book/10.1002/9780470034590/homepage/rf_coils_virtual_issue.htm?cm=on-chem&cs=chem-analytic&cu=sitename-ln&cd=sitename-In-MRIgroup-VI" target="_blank"ultimate online resource for NMR andMRI/a. To date there is no single reference aimed at teaching the art ofapplications guided coil design for use in MRI. This RF Coilsfor MRI handbook is intended to become thisreference. Heretofore, much of the know-how of RF coil design is bottled upin various industry and academic laboratories around the world.Some of this information on coil technologies and applicationstechniques has been disseminated through the literature, while moreof this knowledge has been withheld for competitive or proprietaryadvantage. Of the published works, the record of technologydevelopment is often incomplete and misleading, accuratereferencing and attribution assignment being tantamount toadmission of patent infringement in the commercial arena. Accordingly, the literature on RF coil design is fragmented andconfusing. There are no texts and few courses offered toteach this material. Mastery of the art and science of RF coildesign is perhaps best achieved through the learning that comeswith a long career in the field at multiple places ofemployment…until now. RF Coils for MRI combines the lifetime understandingand expertise of many of the senior designers in the field into asingle, practical training manual. It informs the engineer on partnumbers and sources of component materials, equipment, engineeringservices and consulting to enable anyone with electronics benchexperience to build, test and interface a coil. The handbookteaches the MR system user how to safely and successfully implementthe coil for its intended application. The comprehensive articlesalso include information required by the scientist or physician topredict respective experiment or clinical performance of a coil fora variety of common applications. It is expectedthat RF Coils for MRI becomes an important resource forengineers, technicians, scientists, and physicians wanting tosafely and successfully buy or build and use MR coils in the clinicor laboratory. Similarly, this guidebook provides teachingmaterial for students, fellows and residents wanting to betterunderstand the theory and operation of RF coils. Many of the articles have been written by the pioneers anddevelopers of coils, arrays and probes, so this is all first handinformation! The handbook serves as an expository guide forhands-on radiologists, radiographers, physicians, engineers,medical physicists, technologists, and for anyone with interests inbuilding or selecting and using RF coils to achieve best clinicalor experimental results. About EMR Handbooks / eMagResHandbooks The Encyclopedia of Magnetic Resonance (up to 2012) andeMagRes (from 2013 onward) publish a wide range of onlinearticles on all aspects of magnetic resonance in physics,chemistry, biology and medicine. The existence of this large numberof articles, written by experts in various fields, is enabling thepublication of a series of EMR Handbooks / eMagResHandbooks on specific areas of NMR and MRI. Thechapters of each of these handbooks will comprise a carefullychosen selection of articles from eMagRes. In consultationwith the eMagRes Editorial Board, the EMRHandbooks / eMagRes Handbooks are coherentlyplanned in advance by specially-selected Editors, and new articlesare written (together with updates of some already existingarticles) to give appropriate complete coverage. The handbooks areintended to be of value and interest to research students,postdoctoral fellows and other researchers learning about thescientific area in question and undertaking relevant experiments,whether in academia or industry. Have the content of this Handbook and the complete content ofeMagRes at your fingertips! Visit: ahref="http://www.wileyonlinelibrary.com/ref/eMagRes"www.wileyonlinelibrary.com/ref/eMagRes/a View other eMagRes publications ahref="http://onlinelibrary.wiley.com/book/10.1002/9780470034590/homepage/emagres_publications.htm" target="_blank"here/a

EPR Spectroscopy

EPR Spectroscopy
Fundamentals and Methods

by Daniella Goldfarb,Stefan Stoll

  • Publisher : John Wiley & Sons
  • Release : 2018-03-06
  • Pages : 648
  • ISBN : 1119162971
  • Language : En, Es, Fr & De
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This unique, self-contained resource is the first volume on electron paramagnetic resonance (EPR) spectroscopy in the eMagRes Handbook series. The 27 chapters cover the theoretical principles, the common experimental techniques, and many important application areas of modern EPR spectroscopy. EPR Spectroscopy: Fundamentals and Methods is presented in four major parts: A: Fundamental Theory, B: Basic Techniques and Instrumentation, C: High-Resolution Pulse Techniques, and D: Special Techniques. The first part of the book gives the reader an introduction to basic continuous-wave (CW) EPR and an overview of the different magnetic interactions that can be determined by EPR spectroscopy, their associated theoretical description, and their information content. The second provides the basics of the various EPR techniques, including pulse EPR, and EPR imaging, along with the associated instrumentation. Parts C and D builds on parts A and B and offer introductory accounts of a wide range of modern advanced EPR techniques, with examples of applications. The last two parts presents most of the new advances that do not appear in most of the classical EPR textbooks that focus on CW EPR. EPR Spectroscopy: Fundamentals and Methods contains, in concise form, all the material needed to understand state-of-the-art EPR spectroscopy at the graduate school/research level, whilst the editors have ensured that it presents the topic at a level accessible to newcomers to the field and others who want to know its range of application and how to apply it.

Safety and Biological Effects in MRI

Safety and Biological Effects in MRI
A Book

by Devashish Shrivastava,J. Thomas Vaughan

  • Publisher : John Wiley & Sons
  • Release : 2020-10-30
  • Pages : 520
  • ISBN : 1118821297
  • Language : En, Es, Fr & De
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In vivo magnetic resonance imaging (MRI) has evolved into a versatile and critical, if not ‘gold standard’, imaging tool with applications ranging from the physical sciences to the clinical ‘-ology’. In addition, there is a vast amount of accumulated but unpublished inside knowledge on what is needed to perform a safe, in vivo MRI. The goal of this comprehensive text, written by an outstanding group of world experts, is to present information about the effect of the MRI environment on the human body, and tools and methods to quantify such effects. By presenting such information all in one place, the expectation is that this book will help everyone interested in the Safety and Biological Effects in MRI find relevant information relatively quickly and know where we stand as a community. The information is expected to improve patient safety in the MR scanners of today, and facilitate developing faster, more powerful, yet safer MR scanners of tomorrow. This book is arranged in three sections. The first, named ‘Static and Gradient Fields’ (Chapters 1-9), presents the effects of static magnetic field and the gradients of magnetic field, in time and space, on the human body. The second section, named ‘Radiofrequency Fields’ (Chapters 10-30), presents ways to quantify radiofrequency (RF) field induced heating in patients undergoing MRI. The effect of the three fields of MRI environment (i.e. Static Magnetic Field, Time-varying Gradient Magnetic Field, and RF Field) on medical devices, that may be carried into the environment with patients, is also included. Finally, the third section, named ‘Engineering’ (chapters 31-35), presents the basic background engineering information regarding the equipment (i.e. superconducting magnets, gradient coils, and RF coils) that produce the Static Magnetic Field, Time-varying Gradient Magnetic Field, and RF Field. The book is intended for undergraduate and post-graduate students, engineers, physicists, biologists, clinicians, MR technologists, other healthcare professionals, and everyone else who might be interested in looking into the role of MRI environment on patient safety, as well as those just wishing to update their knowledge of the state of MRI safety. Those, who are learning about MRI or training in magnetic resonance in medicine, will find the book a useful compendium of the current state of the art of the field.

The Handbook of Metabonomics and Metabolomics

The Handbook of Metabonomics and Metabolomics
A Book

by John C. Lindon,Jeremy K. Nicholson,Elaine Holmes

  • Publisher : Elsevier
  • Release : 2011-08-11
  • Pages : 572
  • ISBN : 9780080468006
  • Language : En, Es, Fr & De
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Molecular biology operates at three levels – genes, proteins and metabolites. This book is unique in that it provides a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies (genomics and proteomics). These "omics" methods form the basis for understanding biology at a systems level. The Handbook of Metabonomics and Metabolomics aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification, encompassing the fields of metabonomics and metabolomics. It covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications. * comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies * aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification * covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.

Multidimensional NMR Methods for the Solution State

Multidimensional NMR Methods for the Solution State
A Book

by Gareth A. Morris,James W. Emsley

  • Publisher : John Wiley & Sons
  • Release : 2012-12-19
  • Pages : 576
  • ISBN : 1118589084
  • Language : En, Es, Fr & De
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The content of this volume has been added toeMagRes (formerly Encyclopedia of MagneticResonance) - the ahref="http://onlinelibrary.wiley.com/book/10.1002/9780470034590/homepage/rf_coils_virtual_issue.htm?cm=on-chem&cs=chem-analytic&cu=sitename-ln&cd=sitename-In-MRIgroup-VI" target="_blank"ultimate online resource for NMR and MRI/a. The literature of multidimensional NMR began with thepublication of three papers in 1975, then nine in 1976 and fifteenin 1977, and now contains many tens of thousands of papers. Anyattempt to survey the field must therefore necessarily be veryselective, not to say partial. In assembling this handbook, theEditors have sought to provide both the new researcher and theestablished scientist with a solid foundation for the understandingof multidimensional NMR, a representative if inevitably limitedsurvey of its applications, an authoritative account of classictechniques such as COSY, NOESY and TOSCY, and an account of thelatest progress in the development of multidimensionaltechniques. This handbook is structured in four parts. The first opens withan historical introduction to, and a brief account of, thepracticalities and applications of multidimensional NMR methods,followed by a definitive survey of their conceptual basis and aseries of articles setting out the generic principles of methodsfor acquiring and processing multidimensional NMR data. In thesecond part, the main families of multidimensional techniques,arranged in approximate order of increasing complexity, aredescribed in detail, from simple J-resolved spectroscopy through tothe powerful heteronuclear 3D and 4D methods that now dominate thestudy of structural biology in solution. The third part offers andillustrative selection from the very wide range of applications ofmultidimensional NMR methods, including some of the most recentdevelopments in protein NMR. Finally, the fourth part introducesthe idea of multidimensional spectra containing non-frequencydimensions, in which properties such as diffusion and relaxationare correlated. About EMR Handbooks / eMagResHandbooks The Encyclopedia of Magnetic Resonance (up to 2012) andeMagRes (from 2013 onward) publish a wide range of onlinearticles on all aspects of magnetic resonance in physics,chemistry, biology and medicine. The existence of this large numberof articles, written by experts in various fields, is enabling thepublication of a series of EMR Handbooks / eMagResHandbooks on specific areas of NMR and MRI. Thechapters of each of these handbooks will comprise a carefullychosen selection of articles from eMagRes. In consultationwith the eMagRes Editorial Board, the EMRHandbooks / eMagRes Handbooks are coherentlyplanned in advance by specially-selected Editors, and new articlesare written (together with updates of some already existingarticles) to give appropriate complete coverage. The handbooks areintended to be of value and interest to research students,postdoctoral fellows and other researchers learning about thescientific area in question and undertaking relevant experiments,whether in academia or industry. Have the content of this Handbook and the complete content ofeMagRes at your fingertips! Visit: ahref="http://www.wileyonlinelibrary.com/ref/eMagRes"www.wileyonlinelibrary.com/ref/eMagRes/a View other eMagRes publications ahref="http://onlinelibrary.wiley.com/book/10.1002/9780470034590/homepage/emagres_publications.htm" target="_blank"here /a

NMR Spectroscopy

NMR Spectroscopy
A Versatile Tool for Environmental Research

by Myrna J. Simpson,Andre J. Simpson

  • Publisher : John Wiley & Sons
  • Release : 2014-06-12
  • Pages : 448
  • ISBN : 111861643X
  • Language : En, Es, Fr & De
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The challenges faced by environmental scientists today are vast,complex, and multi-faceted. For instance, predicting the fateof an environmental pollutant or understanding ecosystem responsesto climate change, necessitate a firm understanding of molecularstructure and dynamics of environmental media as well as thecomponents that exist and interact within this media. Furthermore, linking information obtained at the molecular-scale toecosystem-level processes is a major pursuit of modernenvironmental research. As such, NMR spectroscopy and itsscalability from the molecular-scale to the macroscopic-scale, isfacilitating rapid growth in environmental science. In addition,the versatility of NMR spectroscopy has resulted in the developmentand implementation of different types of NMR techniques to examinethe structure of various types of environmental samples, living andnon-living, as well as the study of critical environmentalprocesses. This comprehensive handbook is a collection of chapters thatspan from methods to how NMR is used in environmental research togain insight into various ecosystem properties. It is organized into three parts: Part A focuses on methods used in environmental NMRwhich span from solution-state to magnetic resonanceimaging. Part B emphasizes how NMR spectroscopy plays anessential role in understanding various types of environmentalcomponents and related processes, including different forms oforganic matter found in soil, water, and air as well as how NMR isused to probe the fate of water, organic pollutants, and metals inthe environment. Part C focuses on the growing field of environmentalmetabolomics which uses NMR as its main discoveryplatform. This volume highlights the immense potential of NMR spectroscopyto expand our fundamental understanding of environmental processesand how it will continue to do so well into the future. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of MagneticResonance) publishes a wide range of online articles on allaspects of magnetic resonance in physics, chemistry, biology andmedicine. The existence of this large number of articles, writtenby experts in various fields, is enabling the publication of aseries of eMagRes Handbooks on specific areas of NMR and MRI. Thechapters of each of these handbooks will comprise a carefullychosen selection of eMagRes articles. In consultation with theeMagRes Editorial Board, the eMagRes handbooks arecoherently planned in advance by specially-selected Editors, andnew articles are written to give appropriate complete coverage. Thehandbooks are intended to be of value and interest to researchstudents, postdoctoral fellows and other researchers learning aboutthe scientific area in question and undertaking relevantexperiments, whether in academia or industry. Have the content of this handbook and the complete content ofeMagRes at your fingertips! Visit: ahref="http://www.wileyonlinelibrary.com/ref/eMagRes"www.wileyonlinelibrary.com/ref/eMagRes/a

Handbook of Phosphorus-31 Nuclear Magnetic Resonance Data (1990)

Handbook of Phosphorus-31 Nuclear Magnetic Resonance Data (1990)
A Book

by John C. Tebby

  • Publisher : CRC Press
  • Release : 2017-11-22
  • Pages : 582
  • ISBN : 1351362038
  • Language : En, Es, Fr & De
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To fully utilize Nuclear Magnetic Resonance (NMR) spectroscopy, a comprehensive and well-organized compilation of NMR data is necessary. While compilations have been available for other important NMR nuclei, such as carbon and fluorine, no comprehensive collection of data has been prepared for phosphorus-until now. The CRC Handbook of Phosphorus-31 Nuclear Magnetic Resonance Data provides a collection of 31P NMR chemical shifts for nearly 20,000 organic and inorganic phosphorus compounds. Each class of phosphorus compound is discussed. Bond types, stereochemistry (with the exception of metal complexes), media, important coupling constants, and data sources are included. The information is systematically organized according to coordination state, the atoms bound to phosphorus, and their connectivities. A comprehensive series of bar charts is also included to allow structure types to be assigned to chemical shift data. This handbook is an invaluable resource for all scientists working with phosphorus compounds, including chemists, biochemists, medical researchers, and pharmaceutical chemists.

Nuclear Magnetic Resonance Spectroscopy

Nuclear Magnetic Resonance Spectroscopy
An Introduction to Principles, Applications, and Experimental Methods

by Joseph B. Lambert,Eugene P. Mazzola,Clark D. Ridge

  • Publisher : Wiley
  • Release : 2019-01-04
  • Pages : 480
  • ISBN : 1119295238
  • Language : En, Es, Fr & De
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Combines clear and concise discussions of key NMR concepts with succinct and illustrative examples Designed to cover a full course in Nuclear Magnetic Resonance (NMR) Spectroscopy, this text offers complete coverage of classic (one-dimensional) NMR as well as up-to-date coverage of two-dimensional NMR and other modern methods. It contains practical advice, theory, illustrated applications, and classroom-tested problems; looks at such important ideas as relaxation, NOEs, phase cycling, and processing parameters; and provides brief, yet fully comprehensible, examples. It also uniquely lists all of the general parameters for many experiments including mixing times, number of scans, relaxation times, and more. Nuclear Magnetic Resonance Spectroscopy: An Introduction to Principles, Applications, and Experimental Methods, 2nd Edition begins by introducing readers to NMR spectroscopy - an analytical technique used in modern chemistry, biochemistry, and biology that allows identification and characterization of organic, and some inorganic, compounds. It offers chapters covering: Experimental Methods; The Chemical Shift; The Coupling Constant; Further Topics in One-Dimensional NMR Spectroscopy; Two-Dimensional NMR Spectroscopy; Advanced Experimental Methods; and Structural Elucidation. Features classical analysis of chemical shifts and coupling constants for both protons and other nuclei, as well as modern multi‐pulse and multi-dimensional methods Contains experimental procedures and practical advice relative to the execution of NMR experiments Includes a chapter-long, worked-out problem that illustrates the application of nearly all current methods Offers appendices containing the theoretical basis of NMR, including the most modern approach that uses product operators and coherence-level diagrams By offering a balance between volumes aimed at NMR specialists and the structure-determination-only books that focus on synthetic organic chemists, Nuclear Magnetic Resonance Spectroscopy: An Introduction to Principles, Applications, and Experimental Methods, 2nd Edition is an excellent text for students and post-graduate students working in analytical and bio-sciences, as well as scientists who use NMR spectroscopy as a primary tool in their work.

Clinical Magnetic Resonance Spectroscopy

Clinical Magnetic Resonance Spectroscopy
A Book

by E.B. Cady

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 290
  • ISBN : 1468413333
  • Language : En, Es, Fr & De
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Nobody can know everything. For the successful application of techniques based on nuclear magnetic resonance to clinical problems, it is a vital necessity that individuals with widely different skills should learn a little of each others' trades by co-operation and communication. Ernest Cady has long proved himself a master of these arts to his colleagues at University College London, and by writing this excellent book he extends his experience to a wide circle of readers. Although the nuclear magnetic resonance (NMR) phenomenon had been predicted theoretically (and to some degree demonstrated experimentally) appreciably earlier, it required the advances in electronics that took place during World War II to turn NMR into a practical technique, as demonstrated independently in 1946 by Bloch and Purcell. Since then, NMR has been used extensively and increasingly by chemists and physicists. In the 1970s the first applications of NMR to animal organs yielded important advances in our knowledge of the biochemical and physiological processes as they occur in genuinely intact tissues. They showed incidentally that some conventional techniques introduce significant artifacts.

The Lipid Handbook with CD-ROM, Third Edition

The Lipid Handbook with CD-ROM, Third Edition
A Book

by Frank D. Gunstone,John L. Harwood,Albert J. Dijkstra

  • Publisher : CRC Press
  • Release : 2007-03-13
  • Pages : 1472
  • ISBN : 9781420009675
  • Language : En, Es, Fr & De
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Extensively revised, reorganized, and expanded, the third edition of the industry standard, The Lipid Handbook reflects many of the changes in lipid science and technology that have occurred in the last decade. All chapters have been rewritten, many by new authors, to match the updated thinking and practice of modern lipid science and bring a fresh perspective to twenty years of tradition. Retaining the general structure of the previous editions, The Lipid Handbook with CD-ROM, Third Edition collates a wide range of information into a single volume. New contributions highlight the latest technologies utilized in today's lipid science such as chromatographic analysis and nuclear magnetic resonance spectroscopy. An entirely new chapter is devoted to non-food uses such as lipids as surfactants, cosmetics, and biofuels. Expanded sections illustrate a growing emphasis on lipid metabolism and the nutritional, medical, and agricultural aspects including human dietary requirements and disorders of lipid metabolism. The dictionary section is vastly expanded to cover chemical structure, physical properties, and references to thousands of lipid and lipid related molecules. The handbook now includes a CD-ROM that allows instant access to tabulated and referenced information and can be searched either as the full text or by structure or substructure. Drawing from the best minds in the field, The Lipid Handbook with CD-ROM, Third Edition presents the latest technological developments and the current and future directions and applications of lipid science to the next generation of researchers.