Principles of Molecular Medicine

Principles of Molecular Medicine
A Book

by J. Larry Jameson

  • Publisher : Springer Science & Business Media
  • Release : 1998-07-13
  • Pages : 1127
  • ISBN : 1592597262
  • Language : En, Es, Fr & De
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Within the framework of clinical internal medicine, they will gain critical knowledge of the many powerful molecular biology-based developments now so rapidly enhancing our understanding of the pathophysiology of disease, improving the feasibility and accuracy of diagnostic testing, and opening novel therapeutic avenues, including gene therapy. Readers will also gain a fuller understanding of the role played by genetic defects in a host of diseases, among them peripheral neuropathies, Alzheimer's disease, arrhythmias, leukemias and lymphomas, cystic fibrosis, hepatitis, HIV, autoimmune disorders, polycystic kidney disease, schizophrenia, affective disorders, alcoholism, Huntington's disease, and many more.

Introduction to Molecular Medicine

Introduction to Molecular Medicine
A Book

by Dennis W. Ross

  • Publisher : Springer Science & Business Media
  • Release : 2013-03-09
  • Pages : 174
  • ISBN : 147574076X
  • Language : En, Es, Fr & De
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How will increased understanding of the human genome affect our ability to diagnose and treat disease? The subject of recombinant DNA technology is no longer limited to the research laboratory; it is being discussed in ever-widening medical circles. Introduction to Molecular Medicine is especially written for the physician who is not a genetics expert but wishes to understand this new science and find entry to the more specialized publications. The first chapters present the basic concepts of the human genome and gene regulation. Subsequent chapters consider how today's new approach can be applied in areas such as forensic medicine, transplantation medicine, drug manufacture and genetic engineering. For example, a major section on cancer explores the diagnosis of leukemia and lymphoma through the detection of gene rearrangement and oncongeny mutation. One feature that will especially interest pathologists, pediatricians and residents is the discussion of diagnostic tests that are used in current practice.

Principles of Molecular Cardiology

Principles of Molecular Cardiology
A Book

by Marschall S. Runge,Cam Patterson

  • Publisher : Springer Science & Business Media
  • Release : 2007-11-14
  • Pages : 617
  • ISBN : 1592598781
  • Language : En, Es, Fr & De
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An easy-to-read survey of all the latest developments in molecular cardiologic research and therapy. The authors explain in a readable style the complex process of the heart's development, the molecular basis of cardiovascular diseases, and the translation of these research advances to actual clinical treatments. The expert information provided here serves as an invaluable building block for novel treatments of cardiovascular diseases and includes a comprehensive discussion of cardiac function and dysfunction, coronary artery disease, cardiac arrhythmias, vascular diseases, and risk factors for cardiovascular disease. These state-of-the-art approaches to molecular cardiologic research include critical discussion of such topics as the molecular events that regulate angiogenesis and the potential for angiogenic therapy, emerging therapies for arrhythmias, and a description of the molecular biology of aging and its impact on the cardiovascular system.

An Introduction to Molecular Medicine and Gene Therapy

An Introduction to Molecular Medicine and Gene Therapy
A Book

by Thomas F. Kresina

  • Publisher : John Wiley & Sons
  • Release : 2004-04-07
  • Pages : 416
  • ISBN : 0471461040
  • Language : En, Es, Fr & De
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Gene therapy, or the use of genetic manipulation for diseasetreatment, is derived from advances in genetics, molecular biology,clinical medicine, and human genomics. Molecular medicine, theapplication of molecular biological techniques to disease treatmentand diagnosis, is derived from the development of human organtransplantation, pharmacotherapy, and elucidation of the humangenome. An Introduction to Molecular Medicine and GeneTherapy provides a basis for interpreting new clinical andbasic research findings in the areas of cloning, gene transfer, andtargeting; the applications of genetic medicine to clinicalconditions; ethics and governmental regulations; and the burgeoningfields of genomics, biotechnology, and bioinformatics. By dividingthe material into three sections - an introduction to basicscience, a review of clinical applications, and a discussion of theevolving issues related to gene therapy and molecular medicine-thiscomprehensive manual describes the basic approaches to the broadrange of actual and potential genetic-based therapies. In addition, An Introduction to Molecular Medicine andGene Therapy: Covers new frontiers in gene therapy, animal models, vectors,gene targeting, and ethical/legal considerations Provides organ-based reviews of current studies in gene therapyfor monogenetic, multifactoral or polygenic disorders, andinfectious diseases Includes bold-faced terms, key concepts, summaries, and listsof helpful references by subject in each chapter Contains appendices on commercial implications and a review ofthe history of gene therapy This textbook offers a clear, concise writing style, drawingupon the expertise of the authors, all renowned researchers intheir respective specialties of molecular medicine. Researchers ingenetics and molecular medicine will all find An Introductionto Molecular Medicine and Gene Therapy to be an essentialguide to the rapidly evolving field of gene therapy and itsapplications in molecular medicine.

Molecular Medicine

Molecular Medicine
Genomics to Personalized Healthcare

by R.J. Trent

  • Publisher : Academic Press
  • Release : 2012-08-22
  • Pages : 346
  • ISBN : 0123814529
  • Language : En, Es, Fr & De
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Molecular Medicine is the application of genetic or DNA-based knowledge to the modern practice of medicine. Molecular Medicine, 4e, provides contemporary insights into how the genetic revolution is influencing medical thinking and practice. The new edition includes recent changes in personalized medicine, new growth in omics and direct-to-consumer DNA testing, while focusing on advances in the Human Genome project and implications of the advances in clinical medicine. Graduate students, researchers, clinicians and allied health professionals will appreciate the background history and clinical application of up-to-date molecular advances. Extensively revised to incorporate the results of the Human Genome Project, it provides the latest developments in molecular medicine The only book in Molecular Medicine to reach its fourth edition Identifies current practice as well as future developments Presents extensive tables, well presented figures and resources for further understanding

TEXTBOOK OF BIOCHEMISTRY, BIOTECHNOLOGY, ALLIED AND MOLECULAR MEDICINE

TEXTBOOK OF BIOCHEMISTRY, BIOTECHNOLOGY, ALLIED AND MOLECULAR MEDICINE

by TALWAR, G.P.

  • Publisher : PHI Learning Pvt. Ltd.
  • Release : 2021
  • Pages : 1632
  • ISBN : 8120351258
  • Language : En, Es, Fr & De
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The Fourth Edition of the compendium pools together the knowledge and experience of experts from all over the world, who are engaged in teaching and research in the field of biochemistry, medical sciences and allied disciplines. Comprising 20 sections, the present edition of the book has been substantially revised incorporating the latest research and achievements in the field. Beginning appropriately with chemical architecture of the living systems, role and significance of biochemical reactions, organization of specialised tissues, and importance of food and nutrition, the book explores beyond traditional boundaries of biochemistry. The knowledge of various organ systems has been expanded covering their normal function, ailments and dysfunction. A chapter on Eye and Vision explaining molecular basis of cataract and glaucoma have been added. Also, the book introduces stem cells and regenerative therapy and defines molecules associated with pleasure, happiness, stress and anxiety. A Section on Gastrointestinal and Biliary System elaborates on physiology and dysfunction including fatty liver and its implications, and hepatitis viruses. The knowledge of Human Genetics and Biochemical Basis of Inheritance has been appropriately expanded to reflect the latest advances in various domains. Besides DNA fingerprinting for identity establishment, the Section discusses epigenetics, micro-RNA and siRNA including their role in gene expression, chromatin modification and its association with human diseases, and genetic engineering. It also explores emerging areas such as metabolomics and proteomics; synthetic biology; and dual use technology in bioterrorism. Due emphasis has been given to the Section on Cell Replication and Cancer. Emergence of the use of probiotics in human health has also been highlighted. Besides, an entire Section has been devoted to male and female reproductive systems, fertilization, implantation, pregnancy, lactation, and assisted reproductive technology. Immunology, including vaccines and immunization, has been given due attention with latest updates in this fast growing area. Modern medicine, despite its stupendous advances cannot provide cure for all ailments. Thus, the new edition provides knowledge of alternative medicine systems—Ayurveda, Homeopathy, Unani, Yoga and Herbal Medicine. Incorporating vast information on the latest and emerging areas, the book will be of immense value to the students of medical sciences not only in their preclinical years, but also in all phases of medical course including postgraduate education and practice. Besides, it will also serve as a valuable source to the students of biochemistry and human bi

Molecular Medicine

Molecular Medicine
An Introduction

by Jens Kurreck,Cy Aaron Stein

  • Publisher : John Wiley & Sons
  • Release : 2016-02-16
  • Pages : 404
  • ISBN : 3527331891
  • Language : En, Es, Fr & De
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Easy to read, yet comprehensive, this is the perfect introduction into the molecular basis of disease and the novel treatment options that have become available. The authors, Jens Kurreck and Cy Stein, have both long-standing teaching experience on the subject, one from a biologist's angle, the other with a medical background. Together, they have produced a modern textbook for courses in Molecular Medicine that incorporates modules from immunology to signaling, from virology to gene therapy, and the latest development in personalized medicine.

Molecular Medicine for Clinicians

Molecular Medicine for Clinicians
A Book

by Barry Mendelow,Michèle Ramsay,Nanthakumarn Chetty,Wendy Stevens,Patrick Arbuthnot,Silke Arndt,Sahle Asfaha,Jacqueline Brown,Alexio Capovilla,Arnold Christianson,Gerrit Coetzee,Theresa Coetzer,Leandra Cronjé,Nigel Crowther,Chrisna Durandt,Adriano Duse,Lindsay Earlam,Debbie Glencross,Nerine Gregersen,Kate Hammond,Tabitha Haw,Nicole Holland,Penny Keene,Hendrik Koornhof,Amanda Krause,Anthony Lane,Zane Lombard,Elizabeth Mayne,Marion Munster,Grant Napier,Andries Oelofse,Lillian Ouko,Maria Papathanasopoulos,Alan Paterson,Michael Pepper,Wolfgang Prinz,Natela Rekhviashvili,Nerina Savage,Barry Schoub,Lesley Scott,Mieneke Smit van Dixhoorn,Himla Soodyall,Gwynneth Stevens,Ahmed Wadee,Sarah Walters,Marco Weinberg,Natalie Whalley,Tracey Wiggill,Pascale Willem

  • Publisher : NYU Press
  • Release : 2008-10-01
  • Pages : 531
  • ISBN : 1868147134
  • Language : En, Es, Fr & De
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This book is suitable for undergraduate medical students, as part of their basic sciences training, but is also relevant to interested under- and postgraduate science and engineering students. There is a special focus on the application of molecular medicine in Africa and in developing countries elsewhere.

Clinical Molecular Medicine

Clinical Molecular Medicine
Principles and Practice

by Dhavendra Kumar

  • Publisher : Academic Press
  • Release : 2019-11-30
  • Pages : 606
  • ISBN : 0128094427
  • Language : En, Es, Fr & De
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Clinical Molecular Medicine: Principles and Practice presents the latest scientific advances in molecular and cellular biology, including the development of new and effective drug and biological therapies and diagnostic methods. The book provides medical and biomedical students and researchers with a clear and clinically relevant understanding on the molecular basis of human disease. With an increased focus on new practice concepts, such as stratified, personalized and precision medicine, this book is a valuable and much-needed resource that unites the core principles of molecular biology with the latest and most promising genomic advances. Illustrates the fundamental principles and therapeutic applications of molecular and cellular biology Offers a clinically focused account of molecular heterogeneity Includes comprehensive coverage of many different disorders, including growth and development, cardiovascular, metabolic, skin, blood, digestive, inflammatory, neuropsychiatric disorders, and many more

Polypeptide

Polypeptide
New Insight into Drug Discovery and Development

by Usman Sumo Friend Tambunan

  • Publisher : BoD – Books on Demand
  • Release : 2018-08-16
  • Pages : 88
  • ISBN : 1789234646
  • Language : En, Es, Fr & De
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Peptides are the biomolecules that consist of several amino acid chains linked through peptide bonds. This class of biomolecules is commonly found in living matter, and some of which play an imperative role in their regulation and functional activities. Peptides have been extensively applied in every aspect of human life, including cosmetics, electronics, the food industries, and pharmaceutical fields. Ultimately, peptide commercialization has become a major trend, which has been growing significantly in recent years. Viewed from the scientific perspective described above, the editor believes that the development of peptides in every aspect of human life should be accelerated. As such, this book aims to provide insight and knowledge regarding the current research that has been conducted in this field; hence, this book may encourage the reader to emphasize the importance of peptides in human life and to inspire others to identify the potency of peptides for other applications that still need further exploration. In this book, some of the compelling applications of peptides in biological and health sciences will be introduced. This book comprises an introductory chapter, along with four chapters presented by several prominent scientists who work in the field of peptide research.

Breast Cancer Management and Molecular Medicine

Breast Cancer Management and Molecular Medicine
A Book

by Martine Piccart,William C. Wood,Chie-Mien Hung,Lawrence J. Solin,Fatima Cardoso

  • Publisher : Springer Science & Business Media
  • Release : 2007-03-07
  • Pages : 1028
  • ISBN : 3540282653
  • Language : En, Es, Fr & De
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Tailoring treatment for individual breast cancers is no longer a dream and is now the main goal for current research. This book gives an overview of the most recent techniques, agents and approaches for breast cancer and the individualization of treatment. Particular attention is given to organ-specific tailored approaches, specific populations, patients’ preferences and rehabilitation. Contributions from experts focus on the biomedical research behind the transfer of molecular biology knowledge into the clinical management of patients. This has led to increased survival as well as improved quality of life. The book gives an overview of the latest achievements in breast cancer and their use in clinical practice.

Molecular Genetics and Personalized Medicine

Molecular Genetics and Personalized Medicine
A Book

by D. Hunter Best,Jeffrey J. Swensen

  • Publisher : Springer Science & Business Media
  • Release : 2012-01-04
  • Pages : 246
  • ISBN : 1617795291
  • Language : En, Es, Fr & De
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Genetic testing has become commonplace, and clinicians are frequently able to use knowledge of an individual’s specific genetic differences to guide their course of action. Molecular Genetics and Personalized Medicine highlights developments that have been made in the field of molecular genetics and how they have been applied clinically. It will serve as a useful reference for physicians hoping to better understand the role of molecular medicine in clinical practice. In addition, it should also prove to be an invaluable resource for the basic scientist that wants to better understand how advances in the laboratory are being moved from the bench to the bedside. All chapters are written by experts in their fields and include the most up to date medical information. The authors simplify complex genetic concepts and focus on practical patient related issues. The book will be of great value to pathologists, hematologists/oncologists, clinical geneticists, high-risk obstetricians, general practitioners, and physicians in all other medical specialties who utilize genetic testing to direct therapy.

Molecular Medicine

Molecular Medicine
Genomics to Personalized Healthcare

by R.J. Trent

  • Publisher : Academic Press
  • Release : 2005-05-13
  • Pages : 310
  • ISBN : 9780126990577
  • Language : En, Es, Fr & De
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Molecular medicine is the application of gene or DNA based knowledge to the modern practice of medicine. This book provides contemporary insights into how the genetic revolution is influencing medical thinking and practice on a broad front including clinical medicine, innovative therapies and forensic medicine. Extensively revised just after the completion of the Human Genome Project, it provides the latest in molecular medicine developments The only book in Molecular Medicine that has undergone three editions Current practice as well as future developments identified Extensive tables, well presented figures - resources for further understanding

Science In Medicine

Science In Medicine
The JCI Textbook Of Molecular Medicine

by American Society for Clinical Investigation,

  • Publisher : Jones & Bartlett Learning
  • Release : 2007-10-31
  • Pages : 1157
  • ISBN : 9780763750831
  • Language : En, Es, Fr & De
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Science in Medicine: The JCI Textbook of Molecular Medicine is a collection of acclaimed articles published in the Journal of Clinical Investigation during the Journal’s tenure at Columbia University. The society that publishes the JCI, the American Society for Clinical Investigation (ASCI), is an honor society of physician scientists, representing those who are at the forefront of translating findings in the laboratory to the advancement of clinical practice. This textbook brings together state-of-the-art reviews written by the world's leading authorities, including many ASCI members. The reviews examine the molecular mechanisms underlying a wide array of diseases and disorders affecting all major organ systems. The fundamentals of the organ or physiological systems in question are present alongside the underlying genetic or physiological abnormalities that result in disease. This text illustrates the translation of basic scientific knowledge into the current practice of clinical medicine. The reviews provide an authoritative and comprehensive overview by building on known scientific concepts and treatment of human disease while exploring where these advances might take medicine over the next decade. The book is a valuable resource for medical students, graduate students, house staff, attending and practicing physicians, and biomedical researchers.

Genetics

Genetics
Analysis & Principles

by Robert J. Brooker

  • Publisher : McGraw-Hill
  • Release : 2005
  • Pages : 842
  • ISBN : 9780071110983
  • Language : En, Es, Fr & De
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Handbook of Molecular and Cellular Methods in Biology and Medicine

Handbook of Molecular and Cellular Methods in Biology and Medicine
A Book

by Leland J. Cseke,Peter B. Kaufman,Gopi K. Podila,Chung-Jui Tsai

  • Publisher : CRC Press
  • Release : 2003-11-24
  • Pages : 600
  • ISBN : 9781420041712
  • Language : En, Es, Fr & De
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Since the publication of the best-selling Handbook of Molecular and Cellular Methods in Biology and Medicine, the field of biology has experienced several milestones. Genome sequencing of higher eukaryotes has progressed at an unprecedented speed. Starting with baker's yeast (Saccharomyces cerevisiae), organisms sequenced now include human (Homo sa

From Neuroscience to Neurology

From Neuroscience to Neurology
Neuroscience, Molecular Medicine, and the Therapeutic Transformation of Neurology

by Stephen Waxman

  • Publisher : Elsevier
  • Release : 2004-11-05
  • Pages : 552
  • ISBN : 9780080506982
  • Language : En, Es, Fr & De
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The field of neurology is being transformed, from a therapeutically nihilistic discipline with few effective treatments, to a therapeutic specialty which offers new, effective treatments for disorders of the brain and spinal cord. This remarkable transformation has bridged neuroscience, molecular medicine, and clinical investigation, and represents a major triumph for biomedical research. This book, which contains chapters by more than 29 internationally recognized authorities who have made major contributions to neurotherapeutics, tells the stories of how new treatments for disabling disorders of the nervous system, such as stroke, multiple sclerosis, Parkinson’s disease, and migraine, were developed, and explores evolving themes and technologies that offer hope for even more effective treatments and ultimately cures for currently untreatable disorders of the brain and spinal cord. The first part of this book reviews the development of new therapies in neurology, from their inception in terms of basic science to their introduction into the clinical world. It also explores evolving themes and new technologies. This book will be of interest to everyone – clinicians and basic scientists alike – interested in diseases of the brain and spinal cord, and in the quest for new treatments for these disorders. * Presents the evolution of the field of neurology into a therapeutic discipline * Discusses lessons learned from past successes and applications to ongoing work * Explores the future of this field

TEXTBOOK OF BIOCHEMISTRY, BIOTECHNOLOGY, ALLIED AND MOLECULAR MEDICINE

TEXTBOOK OF BIOCHEMISTRY, BIOTECHNOLOGY, ALLIED AND MOLECULAR MEDICINE

by TALWAR, G.P.

  • Publisher : PHI Learning Pvt. Ltd.
  • Release : 2021
  • Pages : 1632
  • ISBN : 8120351258
  • Language : En, Es, Fr & De
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The Fourth Edition of the compendium pools together the knowledge and experience of experts from all over the world, who are engaged in teaching and research in the field of biochemistry, medical sciences and allied disciplines. Comprising 20 sections, the present edition of the book has been substantially revised incorporating the latest research and achievements in the field. Beginning appropriately with chemical architecture of the living systems, role and significance of biochemical reactions, organization of specialised tissues, and importance of food and nutrition, the book explores beyond traditional boundaries of biochemistry. The knowledge of various organ systems has been expanded covering their normal function, ailments and dysfunction. A chapter on Eye and Vision explaining molecular basis of cataract and glaucoma have been added. Also, the book introduces stem cells and regenerative therapy and defines molecules associated with pleasure, happiness, stress and anxiety. A Section on Gastrointestinal and Biliary System elaborates on physiology and dysfunction including fatty liver and its implications, and hepatitis viruses. The knowledge of Human Genetics and Biochemical Basis of Inheritance has been appropriately expanded to reflect the latest advances in various domains. Besides DNA fingerprinting for identity establishment, the Section discusses epigenetics, micro-RNA and siRNA including their role in gene expression, chromatin modification and its association with human diseases, and genetic engineering. It also explores emerging areas such as metabolomics and proteomics; synthetic biology; and dual use technology in bioterrorism. Due emphasis has been given to the Section on Cell Replication and Cancer. Emergence of the use of probiotics in human health has also been highlighted. Besides, an entire Section has been devoted to male and female reproductive systems, fertilization, implantation, pregnancy, lactation, and assisted reproductive technology. Immunology, including vaccines and immunization, has been given due attention with latest updates in this fast growing area. Modern medicine, despite its stupendous advances cannot provide cure for all ailments. Thus, the new edition provides knowledge of alternative medicine systems—Ayurveda, Homeopathy, Unani, Yoga and Herbal Medicine. Incorporating vast information on the latest and emerging areas, the book will be of immense value to the students of medical sciences not only in their preclinical years, but also in all phases of medical course including postgraduate education and practice. Besides, it will also serve as a valuable source to the students of biochemistry and human bi

Molecular Cardiology for the Cardiologist

Molecular Cardiology for the Cardiologist
A Book

by Bernard Swynghedauw

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 301
  • ISBN : 1461549698
  • Language : En, Es, Fr & De
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Molecular Cardiology for the Cardiologist, Second Edition provides a short, easily readable summary of what the new biology brings to cardiology. Special efforts have been made to include comprehensive diagrams and drawings, as well as teaching tables, and also to keep the size of the second edition within the modest limits of the first edition. The book remains divided into 5 parts. The first part is a general introduction to the new terminology. The second part is devoted to the normal structure of the heart and vessels. Parts 3 and 4 deal with physiopathology. One of the important contributions of molecular biology to cardiology is a better understanding of the general process of adaptation of the heart and vessels to a permanent mechanical overloading. Such a process is generally called remodeling, and results from coordinate changes in the expression of the genes. The last part of the book includes information on gene and cellular therapy.

Molecular Diagnosis of Infectious Diseases

Molecular Diagnosis of Infectious Diseases
A Book

by Jochen Decker,Udo Reischl

  • Publisher : Springer Science & Business Media
  • Release : 2004
  • Pages : 464
  • ISBN : 1592596797
  • Language : En, Es, Fr & De
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This second edition of a classic laboratory manual describes cutting-edge methods for the protein-based diagnosis of infectious diseases. Explaining the latest developments in genomics, proteomics, bioinformatics, biosensors, high-throughput devices, and recombinant technology, the authors apply these new methodologies successfully to the identification and characterization of valuable diagnostic markers, immunomodulatory components, epitope mapping, the production and purification of recombinant antigens, as well as to diagnostic reagents in immunological assays.