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Botulinum Neurotoxin Complex

Botulinum Neurotoxin Complex
A Structural and Biophysical Characterization

by Jiarong Flora Chen

  • Publisher : Unknown Publisher
  • Release : 1998
  • Pages : 300
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Botulinum Toxin E-Book

Botulinum Toxin E-Book
Therapeutic Clinical Practice and Science

by Joseph Jankovic,Alberto Albanese,M. Zouhair Atassi,J. Oliver Dolly,Mark Hallett,Nathaniel H. Mayer

  • Publisher : Elsevier Health Sciences
  • Release : 2009-02-18
  • Pages : 512
  • ISBN : 1437711197
  • Language : En, Es, Fr & De
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The new, therapeutically-focused Botulinum Toxin presents comprehensive, cross-disciplinary guidance on current practices, covering more than 100 non-cosmetic conditions that occur in neurology, physical medicine and rehabilitation, pain medicine, ophthalmology, gastroenterology, urology, orthopedics, and surgery. International contributors review the current understanding of the biology and cellular mechanisms along with relevant research so you can easily apply them to the pathophysiology of the numerous disorders that botulinum toxin is used to treat—such as botulinum toxin applications for the treatment of cranial-cervical dystonias, motor disorders in cerebral palsy, bruxism and temporomandibular disorders, headache, overactive bladder, chronic pelvic pain syndromes, arthritis joint pain, and wound healing. With discussions of the latest in approved treatment practices as well as new and emerging uses, you’ll get in-depth management guidance on the application of the toxin. Provides clinical applications of botulinum toxin for over 100 disorders for immediate access and easy reference during practice and treatment. Covers a broad array of hot topics, including botulinum toxin applications for the treatment of cranial-cervical dystonias, motor disorders in cerebral palsy, bruxism and temporomandibular disorders, headache, overactive bladder, chronic pelvic pain syndromes, arthritis joint pain, and wound healing. Focuses on approved uses with expert advice on thoroughly tested applications but also discusses new and emerging applications to expose you to additional treatment options. Presents the most comprehensive and up-to-date material available so you get all the information you need from this one resource. Offers the cross-disciplinary guidance of the best world-class expertise through an authoritative, international group of authors who demonstrate the applications of botulinum toxin across various specialties.

Mechanism of Botulinum Neurotoxin B Entry Into Cells and Novel Ways to Detect Botulinum Neurotoxin Activity

Mechanism of Botulinum Neurotoxin B Entry Into Cells and Novel Ways to Detect Botulinum Neurotoxin Activity
A Book

by Min Dong

  • Publisher : Unknown Publisher
  • Release : 2004
  • Pages : 192
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Botulinum Neurotoxin Production by Clostridium Botulinum Strain Loch Maree

Botulinum Neurotoxin Production by Clostridium Botulinum Strain Loch Maree
A Book

by Sherly Bellevue

  • Publisher : Unknown Publisher
  • Release : 2007
  • Pages : 102
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Cumulated Index Medicus

Cumulated Index Medicus
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1998
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Index Medicus

Index Medicus
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2004
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Characterization and Stabilization of Clostridium Botulinum Neurotoxin for Medical Use

Characterization and Stabilization of Clostridium Botulinum Neurotoxin for Medical Use
A Book

by Michael Charles Goodnough

  • Publisher : Unknown Publisher
  • Release : 1994
  • Pages : 424
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Synthesis of Mechanism-based Inhibitors of Botulinum Neurotoxin Serotypes A and B

Synthesis of Mechanism-based Inhibitors of Botulinum Neurotoxin Serotypes A and B
A Book

by Matthias Brewer

  • Publisher : Unknown Publisher
  • Release : 2002
  • Pages : 255
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Current Bibliographies in Medicine

Current Bibliographies in Medicine
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1988
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Botulinum Neurotoxin and Tetanus Toxin

Botulinum Neurotoxin and Tetanus Toxin
A Book

by Lance Simpson

  • Publisher : Elsevier
  • Release : 2012-12-02
  • Pages : 436
  • ISBN : 0323141609
  • Language : En, Es, Fr & De
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Botulinum Neurotoxin and Tetanus Toxin covers the mechanism of action, pathogenesis, and treatment of clostridial neurotoxins. The book is organized into four parts encompassing 18 chapters that discuss the origin, structure, pharmacology, toxicology, immunology, assays, and clinical issues of botulinum and tetanus neurotoxins. The introductory part of the book discusses the discovery and production of neurotoxins in various strains of Clostridium bacteria. This text also describes how specific bacteriophages and plasmids mediate the pathogenicity of some types of Clostridium botulinum and Clostridium tetani. The subsequent part provides an overview of issues related to toxin binding, including toxins that may serve as models for botulinum and tetanus neurotoxins. Discussions on the peripheral and central aspects of poisoning transport in the central nervous system and on the antagonistic drugs for clostridial neurotoxins are provided. The third part of the book addresses the antibodies against botulinum neurotoxin. Bioassay in mice and highly sensitive immunoassays, such as reversed passive hemagglutination, reversed passive latex agglutination, radioimmunoassay, and enzyme-linked immunosorbent assay, are presented. The concluding part covers the animal models for these toxins and discusses the diagnosis and treatment of botulism and tetanus in human. The clinical use of Clostridium botulinum toxin type A in ocular and neuromuscular disease is also examined. This book will be of value to protein chemists, microbiologists, virologists, pharmacologists, immunologists, and clinicians.

A Biophysical Characterization of Botulinum Toxin and Cholera Toxin

A Biophysical Characterization of Botulinum Toxin and Cholera Toxin
A Book

by Geoffrey Matthew Kuziemko

  • Publisher : Unknown Publisher
  • Release : 1997
  • Pages : 298
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Botulinum Neurotoxin Injection Manual

Botulinum Neurotoxin Injection Manual
A Book

by Katharine E. Alter, MD,Nicole A. Wilson, PhD, MD

  • Publisher : Demos Medical Publishing
  • Release : 2014-12-15
  • Pages : 110
  • ISBN : 1620700425
  • Language : En, Es, Fr & De
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This comprehensive yet practical guide covers botulinum toxin injections and the wide range of clinical applications for neurologic and other conditions. Intended as both as an introduction for new injectors and a handy reference guide for busy clinicians, the book opens with a brief review of pharmacology, product information and distinctions between the four toxins that are currently approved for use in the U.S. by the FDA, indications and doses for FDA-approved conditions, and accepted and emerging clinical applications. The remainder is an injection manual, organized anatomically and by condition and covering all applications. For each condition or site, information on typical muscle pattern or muscle groups involved, dosing guidelines and dilution for the applicable toxins, number of injection sites and targeting techniques are provided in table format for quick look-up. Anatomic illustrations and cross-sections appear on facing pages to orient injectors and help identify optimal insertion points. An appendix with useful clinical rating scales is also included.

Botulinum Neurotoxin: A Multifunctional Protein for the Development of New Therapeutics

Botulinum Neurotoxin: A Multifunctional Protein for the Development of New Therapeutics
A Book

by Elena Fonfria

  • Publisher : Unknown Publisher
  • Release : 2018
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Botulinum neurotoxin (BoNT) is a major therapeutic agent licensed in neurological indications such as dystonia and spasticity. In recent years, its use has steadily increased in other neurological areas and new therapeutic areas and also in the aesthetic setting. Paradoxically, BoNT is also the causative agent of the disease botulism and a potential bioterrorism toxin. The BoNT family of toxins comprised more than 40 individual members, classified into 7 serotypes and are produced by Gram-positive obligate anaerobic bacteria. BoNTs are enzymatic multi-modular proteins with a complex multistep mechanism of action. Their target site is at peripheral neurons, particularly the neuromuscular junction, at which they inhibit acetylcholine neurotransmission. Despite intense activity in the BoNT field, today there are still gaps in knowledge both in clinical practice and in basic research. The discovery of the structure-function of BoNT and its domains has allowed rational design of new features using molecular engineering. The diversity of BoNT molecules, both natural and engineered, is an invaluable pool from which to design future new therapeutics with unique pharmacological properties for current and novel indications.

Botulinum Toxin

Botulinum Toxin
A Book

by Alastair Carruthers,Jean Carruthers

  • Publisher : Saunders
  • Release : 2005
  • Pages : 141
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Presents up-to-the-minute, practical guidance on the cosmetic and medical uses of botulinum toxin. Succinctly written and lavishly illustrated, this resource focuses on the how to's of botox injection and offers step-by-step guidance on proper techniques, pitfalls, and tricks of the trade. An accompanying DVD shows clips of key techniques so readers can implement the newest procedures into their practice immediately.

Scientific and Therapeutic Aspects of Botulinum Toxic

Scientific and Therapeutic Aspects of Botulinum Toxic
A Book

by Mitchell F. Brin,Mark Hallett,Joseph Jankovic

  • Publisher : Lippincott Williams & Wilkins
  • Release : 2002
  • Pages : 507
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Written by an international group of noted basic scientists and clinicians, this volume presents state-of-the-art information on the mechanisms of action, pharmacology, neurophysiological effects, and therapeutic uses of botulinum neurotoxins. A major portion of the book reviews recent clinical experience and clinical trials with botulinum toxin therapy for strabismus, dystonia, juvenile cerebral palsy, spasticity, hyperhidrosis, gastrointestinal and genitourinary disorders, headache, cosmetic facial conditions, and various disorders involving excessive muscle contraction or pain. Other chapters examine the immunology of botulinum toxins, the use of other chemodenervating agents, and the development of novel neurotoxin constructs.

Studies of Immunity to Clostridium Botulinum Toxin Type C Beta

Studies of Immunity to Clostridium Botulinum Toxin Type C Beta
A Book

by Daniel Clifford Mills

  • Publisher : Unknown Publisher
  • Release : 1977
  • Pages : 274
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Manual of Botulinum Toxin Therapy

Manual of Botulinum Toxin Therapy
A Book

by Daniel Truong,Mark Hallett,Dirk Dressler,Christopher Zachary

  • Publisher : Cambridge University Press
  • Release : 2014-01-23
  • Pages : 315
  • ISBN : 1107025354
  • Language : En, Es, Fr & De
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"This book tries to answer many of the questions posed above with the contributions of a team of international experts. As in the first edition, the emphasis in this book is on technique, so it is richly endowed with illustrations concerning accurate access techniques to help physicians become facile and fully competent"--Provided by publisher.

Clinical Applications of Botulinum Neurotoxin

Clinical Applications of Botulinum Neurotoxin
A Book

by Keith A. Foster

  • Publisher : Springer
  • Release : 2014-07-08
  • Pages : 196
  • ISBN : 149390261X
  • Language : En, Es, Fr & De
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Currently, there are tremendous advances being made in understanding the basic science of both the structure and function of botulinum neurotoxins. This knowledge is opening up opportunities in regard to both therapeutic uses and treatment and protection options for civil and bio-defense applications. This volume fully evaluates the status of neurotoxin research and exploitation. The book is a multi-authored collection of chapters written by the leading authorities responsible for the current scientific and clinical research that is advancing the understanding and exploitation of the neurotoxins and is both up to date and authoritative.

Hyperhidrosis and Botulinum Toxin in Dermatology

Hyperhidrosis and Botulinum Toxin in Dermatology
A Book

by Oliver Philip Kreyden,Roland Böni,Günter Burg

  • Publisher : Karger Medical and Scientific Publishers
  • Release : 2002
  • Pages : 254
  • ISBN : 3805573065
  • Language : En, Es, Fr & De
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In this publication a comprehensive overview on the pathophysiology and treatment of hyperhidrosis with a focus on the new therapy with botulinum toxin is given by renowned experts from Europe and the USA. In the first part the pathophysiology of hyperhidrosis, rare forms of sweating and their symptoms, as well as the different topical and surgical treatments for focal hyperhidrosis are discussed. The second part deals with botulinum toxin. Besides a historic survey of the drug the reader is introduced to the pharmacological particularities and the different modalities of treatment for focal hyperhidrosis. Complications and side effects of the therapy are presented as well. The final chapter is reserved for other dermatological indications like anal fissure and wrinkles.

Critical Reviews in Immunology

Critical Reviews in Immunology
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2007
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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