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Cancer-Leading Proteases

Cancer-Leading Proteases
Structures, Functions, and Inhibition

by Satya Prakash Gupta

  • Publisher : Academic Press
  • Release : 2020-02-03
  • Pages : 526
  • ISBN : 0128181680
  • Language : En, Es, Fr & De
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Cancer-Leading Proteases: Structures, Functions, and Inhibition presents a detailed discussion on the role of proteases as drug targets and how they have been utilized to develop anticancer drugs. Proteases possess outstanding diversity in their functions. Because of their unique properties, proteases are a major focus of attention for the pharmaceutical industry as potential drug targets or as diagnostic and prognostic biomarkers. This book covers the structure and functions of proteases and the chemical and biological rationale of drug design relating to how these proteases can be exploited to find useful chemotherapeutics to fight cancers. In addition, the book encompasses the experimental and theoretical aspects of anticancer drug design based on proteases. It is a useful resource for pharmaceutical scientists, medicinal chemists, biochemists, microbiologists, and cancer researchers working on proteases. Explains the role of proteases in the biology of cancer Discusses how proteases can be used as potential drug targets or as diagnostic and prognostic biomarkers Covers a wide range of cancers and provides detailed discussions on protease examples

Journal of the National Cancer Institute

Journal of the National Cancer Institute
JNCI.

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2002
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Apoptosis and Cancer Therapy

Apoptosis and Cancer Therapy
A Book

by Klaus-Michael Debatin,Simone Fulda

  • Publisher : Wiley-Blackwell
  • Release : 2006-03-17
  • Pages : 1159
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Since most cancer therapies primarily act by inducing apoptosis in tumor cells, insights into the molecular mechanisms regulating apoptosis are crucial to developing novel, more effective treatment strategies. Here, a highly distinguished team of authors from top institutes around the world leads readers from the principles of programmed cell death to the role of apoptosis in cancer development and emerging treatment strategies. Divided into two distinct parts, the first focuses on apoptosis signaling, covering in depth such topics as mitochondria, effector systems, the Bcl-2 family, IAPs, survival pathways, tumor suppressor genes, modulators, lysosomes and phagocytosis. The second section goes on to analyze apoptosis in cancer and cancer therapy, with a detailed look at model systems, molecular diagnosis, cellular stress, DNA damage and repair, molecular targets and therapeutic aspects. With its strong focus on recent developments in cancer therapy, this book is aimed at oncologists, molecular and cell biologists, biochemists, and those working in the pharmaceutical and biotechnological industries.

Cancer Research Program Annual Report to the California State Legislature ...

Cancer Research Program Annual Report to the California State Legislature ...
A Book

by Cancer Research Program (Calif.)

  • Publisher : Unknown Publisher
  • Release : 2000
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Cancer Research

Cancer Research
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Gann : the Japanese journal of cancer research

Gann : the Japanese journal of cancer research
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1981
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Signal Transduction Mechanisms in Cancer

Signal Transduction Mechanisms in Cancer
A Book

by Hans Grunicke

  • Publisher : Springer
  • Release : 1995-10
  • Pages : 148
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Elucidation of the function of oncogenes in tumor suppressor genes revealed that malignant growth can be understood as a malfunction of information transfer systems employed for transmission of stimulatory or inhibitory signals for growth control. This book presents a comprehensive view reflecting our present knowledge of the whole area of molecular biology and biochemistry of positive and negative growth control and the implication of proto-oncogenes and tumor suppressor genes in these mechanisms. On the basis of this information, new strategies for the development of anti-tumor agents are also discussed.

Anticancer Research

Anticancer Research
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1997
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Annual Meeting of the American Association for Cancer Research

Annual Meeting of the American Association for Cancer Research
Proceedings

by American Association for Cancer Research

  • Publisher : Unknown Publisher
  • Release : 1988
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Contains abstracts of the scientific proceedings of the 73rd- annual meetings of the American Association for Cancer Research (1982- ).

Recent Advances in Steroid Hormone Action

Recent Advances in Steroid Hormone Action
A Book

by Virinder K. Moudgil

  • Publisher : Unknown Publisher
  • Release : 1987
  • Pages : 552
  • ISBN : 9780899253138
  • Language : En, Es, Fr & De
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Oncogene

Oncogene
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1994-03
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Standard & Poor's Stock Reports

Standard & Poor's Stock Reports
New York Stock Exchange, American Stock Exchange, Nasdaq Stock Market and regional exchanges

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2001-06
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Cancer and Nutrition

Cancer and Nutrition
A Book

by Kedar N. Prasad,William C. Cole

  • Publisher : Unknown Publisher
  • Release : 1998
  • Pages : 251
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Breast Cancer

Breast Cancer
A Book

by Daniel F. Roses

  • Publisher : W B Saunders Company
  • Release : 1999
  • Pages : 688
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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This practical book is designed to provide all members of the health care team with a comprehensive understanding of breast disease. A unique question and answer format explores every topic from molecular biology through diagnosis, therapy, and rehabilitation. Chapter subheadings take the form of questions, with the text directed at answering these critical questions. Questions take the form of chapter subheadings, with the text directed at answering these critical questions. Contributing authors developed their questions with the needs of colleagues, patients, and family members in mind to help enhance communication among the entire clinical team. Coverage includes oncogenesis diagnosis (including molecular diagnostic techniques), pathology, surgery, chemotherapy, radiation, and more. An abundance of tables and illustrations provides statistical support and clarify important content.

Enzymes

Enzymes
The Fountain of Life

by D. A. Lopez,Klaus Miehlke,R. Michael Williams

  • Publisher : Unknown Publisher
  • Release : 1994
  • Pages : 330
  • ISBN : 9781884303005
  • Language : En, Es, Fr & De
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Reviews the role of enzymes in health and disease, with emphasis on their importance in maintaining our health, disease prevention and their uses in medicine.

Cancer Enzymology

Cancer Enzymology
Proceedings of the Miami Winter Symposia, January 1976

by Julius Schultz,F. Ahmad,Fazal Ahmad

  • Publisher : Unknown Publisher
  • Release : 1976
  • Pages : 347
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Cancer Biochemistry Biophysics

Cancer Biochemistry Biophysics
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1979
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Origins of Human Cancer: Mechanisms of carcinogenesis

Origins of Human Cancer: Mechanisms of carcinogenesis
A Book

by Howard H. Hiatt,James D. Watson,Jay A. Winsten

  • Publisher : Unknown Publisher
  • Release : 1977
  • Pages : 1889
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Principles of Cancer Biology

Principles of Cancer Biology
A Book

by Lewis J. Kleinsmith

  • Publisher : Benjamin-Cummings Publishing Company
  • Release : 2006
  • Pages : 312
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Principles of Cancer Biology, is an engaging book focused on providing readers with a "big picture" view of cancer. Author Lewis Kleinsmith has written an instructional text focusing on key concepts for a general audience. Each chapter contains a list of suggested readings that expand the detail as needed. The text also emphasizes the scientific evidence that underlies cancer biology, and teaches readers to think critically about this evidence- as there are constantly new "breakthroughs" and reports in this field. For readers who need the review, there are brief reviews of several topics related to DNA replication and repair, cell division, cell signaling, and inheritance patterns in chapters where these subjects are relevant. By including these reviews, the text is both accessible and engaging to a broad audience of readers who are studying cancer biology for the first time, as well as an interested general audience. KEY TOPICS: What Is Cancer, Profile of a Cancer Cell, How Cancers Spread, Identifying the Causes of Cancer, Chemicals and Cancer, Radiation and Cancer, Infectious Agents and Cancer, Heredity and Cancer, Oncogenes, Tumor Suppressor Genes and Cancer Overview, Cancer Screening, Diagnosis, and Treatment, Preventing Cancer, Main Types of Cancer, Human Carcinogens. MARKET: For all readers interested in the big picture view of cancer.

Basal and Squamous Cell Skin Cancers of the Head and Neck

Basal and Squamous Cell Skin Cancers of the Head and Neck
A Book

by Randal S. Weber,Michael John Miller,Helmuth Goepfert

  • Publisher : Unknown Publisher
  • Release : 1996
  • Pages : 392
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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