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Modern Clinical Molecular Techniques

Modern Clinical Molecular Techniques
A Book

by Peter Hu,Madhuri Hegde,Patrick Alan Lennon

  • Publisher : Springer Science & Business Media
  • Release : 2012-05-11
  • Pages : 436
  • ISBN : 1461421705
  • Language : En, Es, Fr & De
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This timely book covers the need to know clinical practices for all those involved in molecular laboratory science. The field of molecular medicine is evolving at an astounding speed. Propelled by the new insights and technologies, advances are being made at an unprecedented rate. With dual measure given to today’s breakthroughs, this book is a collection of the most current practices relevant to the clinical molecular laboratorian. It begins with an introductory section on techniques and procedure. It then presents four separate sections on infectious disease, oncology, pre/post-natal, and identity testing, with specific chapters clearly outlining clinical protocols used in daily practice. Modern Clinical Molecular Techniques cuts to the heart of what is essential for the practicing molecular laboratory scientist. It is an outstanding resource for those operating within or looking to set up a clinical molecular laboratory.

Modern Clinical Molecular Techniques

Modern Clinical Molecular Techniques
A Book

by Peter Hu,Madhuri Hegde,Patrick Alan Lennon

  • Publisher : Springer
  • Release : 2016-08-23
  • Pages : 436
  • ISBN : 9781493941483
  • Language : En, Es, Fr & De
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This timely book covers the need to know clinical practices for all those involved in molecular laboratory science. The field of molecular medicine is evolving at an astounding speed. Propelled by the new insights and technologies, advances are being made at an unprecedented rate. With dual measure given to today’s breakthroughs, this book is a collection of the most current practices relevant to the clinical molecular laboratorian. It begins with an introductory section on techniques and procedure. It then presents four separate sections on infectious disease, oncology, pre/post-natal, and identity testing, with specific chapters clearly outlining clinical protocols used in daily practice. Modern Clinical Molecular Techniques cuts to the heart of what is essential for the practicing molecular laboratory scientist. It is an outstanding resource for those operating within or looking to set up a clinical molecular laboratory.

Principles of Molecular Medicine

Principles of Molecular Medicine
A Book

by J. Larry Jameson

  • Publisher : Springer Science & Business Media
  • Release : 1998-07-13
  • Pages : 1127
  • ISBN : 1592597262
  • Language : En, Es, Fr & De
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Within the framework of clinical internal medicine, they will gain critical knowledge of the many powerful molecular biology-based developments now so rapidly enhancing our understanding of the pathophysiology of disease, improving the feasibility and accuracy of diagnostic testing, and opening novel therapeutic avenues, including gene therapy. Readers will also gain a fuller understanding of the role played by genetic defects in a host of diseases, among them peripheral neuropathies, Alzheimer's disease, arrhythmias, leukemias and lymphomas, cystic fibrosis, hepatitis, HIV, autoimmune disorders, polycystic kidney disease, schizophrenia, affective disorders, alcoholism, Huntington's disease, and many more.

Science In Medicine

Science In Medicine
The JCI Textbook Of Molecular Medicine

by American Society for Clinical Investigation,

  • Publisher : Jones & Bartlett Learning
  • Release : 2007-10-31
  • Pages : 1157
  • ISBN : 9780763750831
  • Language : En, Es, Fr & De
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Science in Medicine: The JCI Textbook of Molecular Medicine is a collection of acclaimed articles published in the Journal of Clinical Investigation during the Journal’s tenure at Columbia University. The society that publishes the JCI, the American Society for Clinical Investigation (ASCI), is an honor society of physician scientists, representing those who are at the forefront of translating findings in the laboratory to the advancement of clinical practice. This textbook brings together state-of-the-art reviews written by the world's leading authorities, including many ASCI members. The reviews examine the molecular mechanisms underlying a wide array of diseases and disorders affecting all major organ systems. The fundamentals of the organ or physiological systems in question are present alongside the underlying genetic or physiological abnormalities that result in disease. This text illustrates the translation of basic scientific knowledge into the current practice of clinical medicine. The reviews provide an authoritative and comprehensive overview by building on known scientific concepts and treatment of human disease while exploring where these advances might take medicine over the next decade. The book is a valuable resource for medical students, graduate students, house staff, attending and practicing physicians, and biomedical researchers.

Lecture Notes on Molecular Medicine

Lecture Notes on Molecular Medicine
A Book

by John R. Bradley,David Johnson,David Rubenstein

  • Publisher : Wiley-Blackwell
  • Release : 2001-10-18
  • Pages : 143
  • ISBN : 9780632058396
  • Language : En, Es, Fr & De
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Lecture Notes on Molecular Medicine provides a concise and straightforward introduction to molecular biology, explaining how it is used to understand and treat human disease. This new edition has been written in response to exciting changes in this fast-moving field. Fully updated, it explains the human genome project and how the sequence will change medicine. It also covers many new methods that have been introduced since the first edition was published. Beginning with first principles, the book is a useful primer for any science student new to molecular biology and genetics. It is also an invaluable resource for medical students and practicing doctors who need an understanding of how advances in molecular biology have impacted clinical medicine, especially in the fields of gene therapy and screening. For ease of use Lecture Notes on Molecular Medicine is divided into four sections: Basic Principles: describing the fundamentals of DNA structure and function that underpin molecular biology Biomolecular Tools: covering the manipulation of DNA and RNA and molecular techniques. Understanding Genetics: covering the basic principles of inheritance, biodiversity, gene mapping and expression and gene therapy. Molecular Medicine in Practice: discussing the profound effect which molecular biology has had on medical practice at all levels. This chapter has been greatly expanded in this new edition to cover all the latest developments in the field. A concise introduction to the basic principles & applications of molecular medicine. Explains complicated science in simple terms with clear diagrams. Integrates basic and clinical science by emphasising application to clinical medicine. Expanded chapter examining molecular medicine in clinical practice.

Clinical Science and Molecular Medicine

Clinical Science and Molecular Medicine
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1977
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Includes Abstracts of the Medical Research Society and of the Society's Annual Guest Lectures.

Introduction to Molecular Medicine

Introduction to Molecular Medicine
A Book

by Dennis W. Ross

  • Publisher : Springer Science & Business Media
  • Release : 2013-03-09
  • Pages : 174
  • ISBN : 147574076X
  • Language : En, Es, Fr & De
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How will increased understanding of the human genome affect our ability to diagnose and treat disease? The subject of recombinant DNA technology is no longer limited to the research laboratory; it is being discussed in ever-widening medical circles. Introduction to Molecular Medicine is especially written for the physician who is not a genetics expert but wishes to understand this new science and find entry to the more specialized publications. The first chapters present the basic concepts of the human genome and gene regulation. Subsequent chapters consider how today's new approach can be applied in areas such as forensic medicine, transplantation medicine, drug manufacture and genetic engineering. For example, a major section on cancer explores the diagnosis of leukemia and lymphoma through the detection of gene rearrangement and oncongeny mutation. One feature that will especially interest pathologists, pediatricians and residents is the discussion of diagnostic tests that are used in current practice.

Clinical Molecular Medicine

Clinical Molecular Medicine
Principles and Practice

by Dhavendra Kumar

  • Publisher : Academic Press
  • Release : 2019-11-30
  • Pages : 606
  • ISBN : 0128094427
  • Language : En, Es, Fr & De
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Clinical Molecular Medicine: Principles and Practice presents the latest scientific advances in molecular and cellular biology, including the development of new and effective drug and biological therapies and diagnostic methods. The book provides medical and biomedical students and researchers with a clear and clinically relevant understanding on the molecular basis of human disease. With an increased focus on new practice concepts, such as stratified, personalized and precision medicine, this book is a valuable and much-needed resource that unites the core principles of molecular biology with the latest and most promising genomic advances. Illustrates the fundamental principles and therapeutic applications of molecular and cellular biology Offers a clinically focused account of molecular heterogeneity Includes comprehensive coverage of many different disorders, including growth and development, cardiovascular, metabolic, skin, blood, digestive, inflammatory, neuropsychiatric disorders, and many more

Symposium

Symposium
The Future of Molecular Medicine and Clinical Research : an International Symposium in Honor of Dr. Jacques Genest

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1986
  • Pages : 84
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Breast Cancer Management and Molecular Medicine

Breast Cancer Management and Molecular Medicine
A Book

by Martine Piccart,William C. Wood,Chie-Mien Hung,Lawrence J. Solin,Fatima Cardoso

  • Publisher : Springer Science & Business Media
  • Release : 2007-03-07
  • Pages : 1028
  • ISBN : 3540282653
  • Language : En, Es, Fr & De
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Tailoring treatment for individual breast cancers is no longer a dream and is now the main goal for current research. This book gives an overview of the most recent techniques, agents and approaches for breast cancer and the individualization of treatment. Particular attention is given to organ-specific tailored approaches, specific populations, patients’ preferences and rehabilitation. Contributions from experts focus on the biomedical research behind the transfer of molecular biology knowledge into the clinical management of patients. This has led to increased survival as well as improved quality of life. The book gives an overview of the latest achievements in breast cancer and their use in clinical practice.

Clinical Science (majalah) Clinical Science and Molecular Medicine (majalah).

Clinical Science (majalah) Clinical Science and Molecular Medicine (majalah).
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1968
  • Pages : 70
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Molecular Pathology

Molecular Pathology
The Molecular Basis of Human Disease

by William B. Coleman,Gregory J. Tsongalis

  • Publisher : Academic Press
  • Release : 2017-11-09
  • Pages : 802
  • ISBN : 0128027878
  • Language : En, Es, Fr & De
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As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

Molecular Medicine for Clinicians

Molecular Medicine for Clinicians
A Book

by Barry Mendelow,Michèle Ramsay,Nanthakumarn Chetty,Wendy Stevens

  • Publisher : NYU Press
  • Release : 2008-01-01
  • Pages : 816
  • ISBN : 1776142373
  • Language : En, Es, Fr & De
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The insights following the wake of the Human Genome project are radically influencing our understanding of the molecular basis of life, health and disease. The improved accuracy and precision of clinical diagnostics is also beginning to have an impact on therapeutics in a fundamental way. This book is suitable for undergraduate medical students, as part of their basic sciences training, but is also relevant to interested under- and postgraduate science and engineering students. It serves as an introductory text for medical registrars in virtually all specialties, and is also of value to the General Practitioner wishing to keep up to date, especially in view of the growing, internet-assisted public knowledge of the field. There is a special focus on the application of molecular medicine in Africa and in developing countries elsewhere.

Facioscapulohumeral Muscular Dystrophy (FSHD)

Facioscapulohumeral Muscular Dystrophy (FSHD)
Clinical Medicine and Molecular Cell Biology

by David Cooper,Meena Upadhhyaya

  • Publisher : Garland Science
  • Release : 2004-03-01
  • Pages : 250
  • ISBN : 1135321663
  • Language : En, Es, Fr & De
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Facioscapulohumeral muscular dystrophy (FSHD) is a genetic disorder involving slowly progressive muscle degeneration in which the muscles of the face, shoulder blades and upper arms are among the most severely affected. It is the third most common inherited muscular dystrophy, affecting 1 in 20,000. The search for the molecular basis of the disease is of interest to all genetic researchers, involving a deletion outside a coding region resulting in over-expression of adjacent genes. This volume summarizes the current understanding of the disorder, including clinical, molecular and therapeutic aspects.

The Molecular Medicine of Viral Hepatitis

The Molecular Medicine of Viral Hepatitis
A Book

by Tim J. Harrison,Arie J. Zuckerman

  • Publisher : Wiley
  • Release : 1997-01-24
  • Pages : 282
  • ISBN : 9780471969969
  • Language : En, Es, Fr & De
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This series is designed to bridge the gap between pure research in the biomedical sciences and its practical application in clinical medicine. The objective is to promote the understanding of the molecular basis of human physiology and disease, and new techniques for diagnosis and treatment. Primarily intended for graduate students of medicine, the books will also be of use to molecular biologists, biochemists, physiologists, pharmacologists and biotechnologists, as well as medical practitioners and technicians who seek to update their knowledge. The Molecular Medicine of Viral Hepatitis Edited by Tim J. Harrison and Arie J. Zuckerman Royal Free Hospital School of Medicine, London, UK General texts on diagnostic and clinical aspects of viral hepatitis abound. The Molecular Medicine of Viral Hepatitis focuses on those areas of research where advances are presently being mode and offers new ideas on the development of vaccines, diagnostic tests and therapeutic agents. Chapters include: The molecular biology of attenuation of hepatitis A virus Development of vaccines against hepatitis E virus infection The molecular role of hepatitis B virus in the development of hepatocellular carcinoma Genotypes and genetic variation of hepatitis C virus As such this volume will be indispensable to clinicians and researchers in virology, hepatology, microbiology, vaccinology, oncology and gastroenterology.

Molecular Genetics and Personalized Medicine

Molecular Genetics and Personalized Medicine
A Book

by D. Hunter Best,Jeffrey J. Swensen

  • Publisher : Humana Press
  • Release : 2014-02-23
  • Pages : 246
  • ISBN : 9781627039239
  • Language : En, Es, Fr & De
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Genetic testing has become commonplace, and clinicians are frequently able to use knowledge of an individual’s specific genetic differences to guide their course of action. Molecular Genetics and Personalized Medicine highlights developments that have been made in the field of molecular genetics and how they have been applied clinically. It will serve as a useful reference for physicians hoping to better understand the role of molecular medicine in clinical practice. In addition, it should also prove to be an invaluable resource for the basic scientist that wants to better understand how advances in the laboratory are being moved from the bench to the bedside. All chapters are written by experts in their fields and include the most up to date medical information. The authors simplify complex genetic concepts and focus on practical patient related issues. The book will be of great value to pathologists, hematologists/oncologists, clinical geneticists, high-risk obstetricians, general practitioners, and physicians in all other medical specialties who utilize genetic testing to direct therapy.

Laboratory Medicine Into the Next Millennium

Laboratory Medicine Into the Next Millennium
Ifcc-Worldlab: 17th International and 13th European Congress of Clinical Chemistry and Laboratory Medicine; 1st International Congress of Clinical Molecular Biology (Cmb); 31st National Congress of the Italian Society of Clinical Biochemistry And...

by 1999 Firenze> International Federation of Clinical Chemistry and Laboratory Medicine,International Federation of Clinical Chemistry and Laboratory Medicine Committee,Società Italiana di Biochimica Clinica e Biologia Molecolare Clinica Staff,1999 Firenze> International Congress of Clinical Chemistry and Laboratory Medicine,International Congress of Clinical Chemistry and Laboratory Medicine Staff,1999 Firenze> European Congress of Clinical Chemistry and Laboratory Medicine,European Congress of Clinical Chemistry and Laboratory Medicine Staff,1999 Firenze> International Congress of Clinical Molecular Biology,International Congress of Clinical Molecular Biology Staff

  • Publisher : Walter de Gruyter
  • Release : 1999-01-01
  • Pages : 564
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Advances in Molecular Pathology, E-Book 2021

Advances in Molecular Pathology, E-Book 2021
A Book

by Gregory J Tsongalis

  • Publisher : Elsevier Health Sciences
  • Release : 2021-11-28
  • Pages : 129
  • ISBN : 0323813364
  • Language : En, Es, Fr & De
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Advances in Molecular Pathology is an annual review publication that covers the current practices and latest developments in the field of Molecular Pathology. Each issue is divided into sections for comprehensive coverage of all subspecialty areas within molecular pathology, including, Genetics, Hematopathology, Infectious Disease, Pharmacogenomics, Informatics, Solid Tumors, and special topics on COVID-19. The Editor-in-Chief of the publication is Dr. Gregory Tsongalis, a leading expert in the field. Topics covered this year include but are not limited to: Phenotype Association and Variant Pathogenicity Prediction Tools in Genomic Analysis; The application of noninvasive prenatal screening to detect copy number variations; Next generation cytogenomics using optical mapping; Review of molecular in APL; NGS for MRD in acute leukemia; Review of emerging technologies as they pertain to infectious disease testing; Germline genetic variants that predict drug response; Nutrigenomics; PGx of hypertension; Genomic data for blood typing, specifically both through NGS and arrays; Preanalytic Variables and Tissue Stewardship for Reliable Next-Generation Sequencing (NGS) Clinical Analysis; and Cell-free nucleic acids in cancer: Current approaches, challenges, and future directions.

Molecular Pathology of Endocrine Diseases

Molecular Pathology of Endocrine Diseases
A Book

by Jennifer L. Hunt

  • Publisher : Springer
  • Release : 2016-08-23
  • Pages : 282
  • ISBN : 9781489979148
  • Language : En, Es, Fr & De
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The past two decades have seen an ever accelerating growth in knowledge about molecular pathology of human diseases, which received a large boost with the sequencing of the human genome in 2003. Mole- lar diagnostics, molecular targeted therapy, and genetic therapy are now routine in many medical centers. The molecular field now impacts every field in medicine, whether clinical research or routine patient care. There is a great need for basic researchers to understand the potential clinical implications of their research whereas private practice clinicians of all types (general internal medicine and internal medicine specialists, medical oncologists, radiation oncologists, surgeons, pediatricians, family practitioners), clinical inves- gators, pathologists and medical laboratory directors, and radiologists require a basic understanding of the fundamentals of molecular pathogenesis, diagnosis, and treatment for their patients. Traditional textbooks in molecular biology deal with basic science and are not readily applicable to the medical setting. Most medical textbooks that include a mention of molecular pathology in the clinical setting are limited in scope and assume that the reader already has a working knowledge of the basic science of molecular biology. Other texts emphasize technology and testing procedures without integrating the clinical perspective. There is an urgent need for a text that fills the gap between basic science books and clinical practice.

Molecular Bacteriology

Molecular Bacteriology
Protocols and Clinical Applications

by Neil Woodford,Alan Johnson

  • Publisher : Springer Science & Business Media
  • Release : 1998-04-30
  • Pages : 682
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The enormous advances in molecular biology that have been witnessed in . Not recent years have had major impacts on many areas of the biological sciences least of these has been in the field of clinical bacteriology and infectious disease . Molecular Bacteriology: Protocols and ClinicalApplications aims to provide the reader with an insight into the role that molecular methodology has to play in modern medical bacteriology. The introductory chapter ofMolecular Bacteriology: ProtocolsandCli- cal Applications offers a personal overview by a Consultant Medical Microbio- gist of the impact and future potential offered by molecular methods. The next six chapters comprise detailed protocols for a range of such methods . We believe that the use of these protocols should allow the reader to establish the various methods described in his or her own laboratory. In selecting the methods to be included in this section, we have concentrated on those that, arguably, have greatest current relevance to reference clinical bacteriology laboratories; we have deliberately chosen not to give detailed protocols for certain methods, such as multilocus enzyme electrophoresis that, in our opinion, remain the preserve of specialist la- ratories and that are not currently suited for general use. We feel that the methods included in this section will find increasing use in diagnostic laboratories and that it is important that the concepts, advantages, and limitations of each are th- oughly understood by a wide range of workers in the field .