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Clinical Perspectives and Targeted Therapies in Apoptosis

Clinical Perspectives and Targeted Therapies in Apoptosis
Drug Discovery, Drug Delivery, and Disease Prevention

by Rupinder K. Sodhi,Jitender Madan

  • Publisher : Academic Press
  • Release : 2020-10-30
  • Pages : 432
  • ISBN : 0128157631
  • Language : En, Es, Fr & De
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Clinical Perspectives and Targeted Therapies in Apoptosis: Drug Discovery, Drug Delivery, and Disease Prevention provides comprehensive coverage, from basic cell biology, to modern assessment techniques for apoptosis in all major disease areas. Chapters provide an introduction to the fundamentals of cell biology, biochemical mechanisms, and the pathophysiological consequences of apoptosis. In addition, the book covers the tools and techniques used to quantify apoptosis and the significance of apoptosis in drug discovery, drug delivery, and its applications in disease prevention. Finally, the book provides a comprehensive compilation of the apoptosis targeting drugs that recently underwent clinical trials. This combination of fundamentals, along with applications in drug discovery, drug delivery, and clinical research make this book a useful resource for those in both academia and industry who are engaged in pharmaceutical, biomedical and biotechnology research. Offers standard and innovative therapeutic approaches to modulate apoptosis in clinical interventions, such as cardiovascular diseases, immune disorders, cancer chemotherapy and neurological ailments Covers cutting-edge laboratory techniques and traditional protocols to determine apoptosis, both in vitro and in vivo Examines clinical study reports of new drug moieties that are explored for various pathological conditions associated with apoptosis

Index Medicus

Index Medicus
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2004
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Pharmaceutical Perspectives of Cancer Therapeutics

Pharmaceutical Perspectives of Cancer Therapeutics
A Book

by Yi Lu,Ram I. Mahato

  • Publisher : Springer Science & Business Media
  • Release : 2009-06-23
  • Pages : 694
  • ISBN : 9781441901316
  • Language : En, Es, Fr & De
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Pharmaceutical Perspectives of Cancer Therapeutics covers a wide variety of therapeutic approaches including gene therapy, immunological therapy; cancer vaccines; strategy for solid tumors as well as for hematological cancers; methods to suppress tumor angiogenesis and metastasis; development and utilization of relevant animal models; introduction of new concepts such as cancer stem cells and new technologies, such as DNA and tissue microarrays; and RNA interference. In addition, clinical application, the development of DNA diagnosis biomarkers and cancer prevention, as well as the utilization of imaging in cancer therapy are also discussed. The use of synthetic carriers, such as lipids, polymers, and peptides for delivery and targeting of small molecules, proteins, and nucleic acids to cancer cells in vivo are discussed. Pharmaceutical Perspectives of Cancer Therapeutics also includes cancer therapy modality in surgery, chemotherapy, and radiotherapy, as well as in combination or multi-modality, giving our book a more focused view of cancer therapy.

Oral and Maxillofacial Surgery

Oral and Maxillofacial Surgery
A Book

by Raymond J. Fonseca

  • Publisher : Saunders
  • Release : 2009
  • Pages : 1004
  • ISBN : 9781416066552
  • Language : En, Es, Fr & De
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This comprehensive resource provides in-depth information to help you perfect your oral and maxillofacial surgical technique and provide state-of-the-art care for your patients. The full scope of the field is represented with up-to-date, evidence-based coverage of every surgical procedure performed today. Volume I: Anesthesia and Pain Control, Dentoalveolar Surgery, Practice Management, Implant Surgery brings you authoritative coverage of office-based procedures, including extractions, implants, and biopsies. [editor].

BMJ

BMJ
British Medical Journal

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2001
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Journal of the National Cancer Institute

Journal of the National Cancer Institute
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2004
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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"Summaries of papers" contained in the journal accompany each issue, 19--

Veterinary Cancer Society Newsletter

Veterinary Cancer Society Newsletter
A Book

by Veterinary Cancer Society

  • Publisher : Unknown Publisher
  • Release : 1995
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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American Journal of Respiratory and Critical Care Medicine

American Journal of Respiratory and Critical Care Medicine
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2005
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Downey and Darling's Physiological Basis of Rehabilitation Medicine

Downey and Darling's Physiological Basis of Rehabilitation Medicine
A Book

by Erwin G. Gonzalez,Stanley J. Myers,Joan E. Edelstein,James L. Lieberman

  • Publisher : Butterworth-Heinemann Medical
  • Release : 2001
  • Pages : 890
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The third edition of this classic text provides a scientific basis for practicing rehabilitation medicine. You will gain a more complete understanding of how physical losses affect the overall function of the patient and how the human body adapts to and compensates for the stress produced by the original injury. Selected topics include adaptation and compensatory adjustments in patients with neurologic, musculoskeletal, and circulatory impairments.

Cancer Drug Design and Discovery

Cancer Drug Design and Discovery
A Book

by Stephen Neidle

  • Publisher : Academic Press
  • Release : 2013-09-30
  • Pages : 640
  • ISBN : 0123972280
  • Language : En, Es, Fr & De
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Cancer Drug Design and Discovery, Second Edition is an important reference on the underlying principles for the design and subsequent development of new anticancer small molecule agents. New chapters have been added to this edition on areas of particular interest and therapeutic promise, including cancer genomics and personalized medicine, DNA-targeted agents and more. This book includes several sections on the basic and applied science of cancer drug discovery and features those drugs that are now approved for human use and are in the marketplace, as well as those that are still under development. By highlighting some of the general principles involved in taking molecules through basic science to clinical development, this book offers a complete and authoritative reference on the design and discovery of anticancer drugs for translational scientists and clinicians involved in cancer research. Provides a clinical perspective on the development of new molecularly targeted anticancer agents with the latest and most promising chemotherapeutic approaches Offers a broad view of where the field is going, what tools drug discovery is using to produce new agents and how they are evaluated in the laboratory and clinic Features 6 new chapters devoted to advances in technology and successful anticancer therapies, such as cancer genomics and personalized medicine, DNA-targeted agents, B-Raf inhibitors and more Each chapter includes extensive references to the primary and review literature, as well as to relevant web-based sources

Seminars in Diagnostic Pathology

Seminars in Diagnostic Pathology
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Alternative and Complementary Therapies for Cancer

Alternative and Complementary Therapies for Cancer
Integrative Approaches and Discovery of Conventional Drugs

by Moulay Alaoui-Jamali

  • Publisher : Springer Science & Business Media
  • Release : 2010-09-02
  • Pages : 722
  • ISBN : 9781441900203
  • Language : En, Es, Fr & De
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Cancer is a common disease with a devastating impact on the physical and psychological well being of patients. The diagnosis of cancer brings upon many clinical challenges and questions for which clear and simple answers are not always provided by modern medicine. To date, only limited therapeutic options are available for patients with advanced cancer. The recent shift toward targeted therapies has improved substantially patient’s survival, however, relapses are frequent and cure remains rare. This led patients and many health care managers to shift attention to the holistic approach of traditional medicine particularly preparations from herbal products to manage and alleviate the disease. Typically, herbal preparations contain single or multiple plant ingredients, including a number of potential active components. Yet, they remain classified as food supplements and thus are exempt from regulations on quality control and proof of efficacy that govern standard pharmaceuticals. Clinical evidence for many preparations is often based on non-documented or anecdotal evidence. In consequence, several preparations with unproven efficacy are circulating in the market with the fear of interference with standard cancer therapies and/or severe toxicity that some can generate, in addition to the unjustified economical burden to patients. Despite inconsistent and conflicting clinical results single molecules have been isolated from herbal preparations and many are exploited to develop potential novel agents. This has fostered the need to organize a set of timely, in-depth and up-to-date review covering the latest developments in alternative cancer management from a scientific and clinical perspective dedicated to the medical community and health care providers, as well as to patients and their families. This book brings the latest comprehensive cancer information and practical recommendations on the best documented practice of alternative therapies for cancer management put together by recognized experts in the fields of medical oncology, traditional medicine, and cancer pharmacology. It goes hand-in-hand with the patient’s medical treatment options, quality of life issues, and more. The book is organized into four major sections: The first is an overview of the cancer syndrome by renowned medical oncologists from the USA and Europe. The second is a comprehensive description of traditional medicine by renowned experts from China and Germany. The third is an overview on the pharmacological impact of herb-based formulations on standard chemotherapy agents used in clinical practice. The fourth is a survey of cases reports from several hospitals with approved practice of alternative medicine. The book will feature simple definitions and essential information grouped in both medical and lay-term terminology, and straightforward illustrations related to human physiology, disease definition, scientific data on know and potential mechanisms of action, and preventive approaches. Finally, the book will feature collaboration of experts from China, India, USA, Canada, Germany, France, and other centres with recognized expertise in alternative/traditional medicine. This international cooperation is crucial to cover the complex topic of alternative therapies for cancer.

Cancer Forum

Cancer Forum
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2002
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Anticancer Research

Anticancer Research
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Origin of Cancers

Origin of Cancers
Clinical Perspectives and Implications of a Stem-Cell Theory of Cancer

by Shi-Ming Tu

  • Publisher : Springer Science & Business Media
  • Release : 2010-07-20
  • Pages : 237
  • ISBN : 9781441959683
  • Language : En, Es, Fr & De
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Précis This book is a treatise about the origin of cancers. I would like to convince readers that the basic tenets of the theory of a stem-cell origin of cancers also constitute a unified theory of cancer. Stem-cell origin of normal (and cancer) cells: Vitruvian version Every truth passes through three stages before it is recognized. In the first it is ridiculed, in the second, it is opposed, in the third, it is regarded as self-evident. – Arthur Schopenhauer v vi Preface Every person has a unique story to tell. My story is about cancer. Cancer touches the lives of countless people. Often enough, it leaves indelible tracks. Many lives have been lost; others are forever changed. For those who confront this deadly scourge, there is a sense of urgency, if not of desperation. For those who face im- nent death, life becomes even more precious and carries a special meaning. As an oncologist, I am touched daily by cancer. I feel its inception, evolution, and aft- math. It seems as though we are fighting an incessant war against cancer at the front line in the trenches. This is my story about cancer. Some people are terrific storytellers. Others have incredible tales to tell.

Journal of Investigational Allergology & Clinical Immunology

Journal of Investigational Allergology & Clinical Immunology
Official Organ of the International Association of Asthmology (INTERASMA) and Sociedad Latinoamericana de Alergia E Inmunologi(a

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1996
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries

Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries
Peptides, Proteins and Nucleic Acids : Small Molecule Organic Chemical Diversity : 2004 Collected Papers, Eighth International Symposium, London, England, UK

by Roger Epton

  • Publisher : Unknown Publisher
  • Release : 2004
  • Pages : 343
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Physiologic and Pathologic Angiogenesis

Physiologic and Pathologic Angiogenesis
Signaling Mechanisms and Targeted Therapy

by Dan Simionescu,Agneta Simionescu

  • Publisher : BoD – Books on Demand
  • Release : 2017-04-05
  • Pages : 464
  • ISBN : 9535130234
  • Language : En, Es, Fr & De
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The purpose of this book is to highlight novel advances in the field and to incentivize scientists from a variety of fields to pursue angiogenesis as a research avenue. Blood vessel formation and maturation to capillaries, arteries, or veins is a fascinating area which can appeal to multiple scientists, students, and professors alike. Angiogenesis is relevant to medicine, engineering, pharmacology, and pathology and to the many patients suffering from blood vessel diseases and cancer, among others. We are hoping that this book will become a source of inspiration and novel ideas for all.

Cancer Research

Cancer Research
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2008-08
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Compendium of Awards

Compendium of Awards
A Book

by Tobacco-Related Disease Research Program (University of California (System))

  • Publisher : Unknown Publisher
  • Release : 2002
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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