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Colorectal Neoplasia and the Colorectal Microbiome

Colorectal Neoplasia and the Colorectal Microbiome
Dysplasia, Probiotics, and Fusobacteria

by Martin H. Floch

  • Publisher : Academic Press
  • Release : 2020-08-15
  • Pages : 270
  • ISBN : 0128225610
  • Language : En, Es, Fr & De
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Colorectal Neoplasia and the Microbiome: Dysplasia, Probiotics, and Fusobacteria provides foundational knowledge on the gut microbiome and evidence for an association with colorectal neoplasia. It covers the role of microbiota in causing adenomatous polyps and colorectal cancer as well as the modulatory effect of diet and probiotics. Chapters explain a foundational history of microbiology in the colon, the epidemiology of colon polyps and cancer, dysbiosis, the role of immunology and bacteria, and the diet. The book combines medical and scientific aspects to show mechanistic aspects between microbiota and hosts, clearly presenting the association between microbiota, colonic lesions and possible causal links. The book is essential reading for everyone working with human microbiota including basic scientists, physiologists of the intestine, experts in intestinal microbiota, gastroenterologists, oncologists and surgeon. Provides foundational background on the complete history of microbiology in the colon Offers thorough coverage of the connection between fusobacterium nucleatum, diet and bacteria on colon health Presents the connection between immunology and bacteria in the colon

Microbiome Insults on the Way to Colorectal Cancer

Microbiome Insults on the Way to Colorectal Cancer
The Impact of Noninvasive Bacteria on Immune Response and Tumorigenesis

by Jackline Joy Martin Lasola

  • Publisher : Unknown Publisher
  • Release : 2013
  • Pages : 118
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Gut Microbiome-Related Diseases and Therapies

Gut Microbiome-Related Diseases and Therapies
A Book

by Maria Gazouli,George Theodoropoulos

  • Publisher : Springer Nature
  • Release : 2021-04-24
  • Pages : 326
  • ISBN : 3030596427
  • Language : En, Es, Fr & De
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This book reviews recent knowledge of the role of gut microbiome in health and disease. It covers extensive topics for several diseases, including metabolic-related diseases, allergies, gastrointestinal diseases, psychiatric diseases, and cancer, while also discussing therapeutic approaches by microbiota modification. Comprehensive and cutting-edge, Gut Microbiome-Related Diseases and Therapies deepens a reader’s theoretical expertise in gut microbiome. Graduate and postdoctoral students, medical doctors, and biomedical researchers will benefit from this book.

The Human Microbiome and Cancer

The Human Microbiome and Cancer
A Book

by Gary Moran,Nezar Al-Hebshi

  • Publisher : Frontiers Media SA
  • Release : 2020-09-03
  • Pages : 329
  • ISBN : 2889639894
  • Language : En, Es, Fr & De
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Understanding Pathophysiology 3e Australia New Zealand

Understanding Pathophysiology 3e Australia New Zealand
A Book

by Judy Craft,Christopher Gordon,Sue E. Huether,Kathryn L. McCance,Valentina L. Brashers

  • Publisher : Mosby Limited
  • Release : 2018-08-10
  • Pages : 1400
  • ISBN : 0729586332
  • Language : En, Es, Fr & De
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Written by Judy Craft and Christopher Gordon, Understanding Pathophysiology 3e remains Australia and New Zealand's leading pathophysiology text for nursing and allied health students. Updated to include the most current scientific and clinical case material across the life span, complex subject manner is presented in an approachable and easy-to-understand format. Beginning with essential concepts, the text examines the normal structure and function of each body system, followed by the alterations to that system caused by disease. Conditions particularly relevant to children and to the ageing are described in separate sections in each chapter to demonstrate disease processes across the life span. Strong ANZ pathophysiological focus -- with disease and disorder profiles specific to the region explained in greater detail and with an epidemiological focus Expert editors, clinicians, researchers and academic writers Recent developments in evidence-based practice for diseases and disorders incorporated throughout Evolve Student Resources: eBook on VitalSource Animations Glossary References Evolve Instructor Resources: Answer Guides to in-print features Focus on Learning, Case Studies and Review Questions Image collection Instructor's Manual PowerPoints References Test Bank NEW chapter on diabetes to highlight the prevalence of the disease in Australia and New Zealand Expanded obesity chapter to reflect the chronic health complications and comorbidities New concept maps designed to stand out and pull together key chapter concepts and processes Updated Focus on Learning, Case Studies and Chapter Review Questions Now includes an eBook with all print purchases

Intestinal Microbiota in the Adenoma Progression to Colorectal Cancer

Intestinal Microbiota in the Adenoma Progression to Colorectal Cancer
A Cross-sectional Study

by Anna Brujats Rubirola

  • Publisher : Unknown Publisher
  • Release : 2014
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Inflammation, Infection, and Microbiome in Cancers

Inflammation, Infection, and Microbiome in Cancers
Evidence, Mechanisms, and Implications

by Jun Sun

  • Publisher : Springer Nature
  • Release : 2021
  • Pages : 329
  • ISBN : 3030679519
  • Language : En, Es, Fr & De
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Illuminating Colorectal Cancer Genomics by Next-Generation Sequencing

Illuminating Colorectal Cancer Genomics by Next-Generation Sequencing
A Big Chapter in the Tale

by Khalid El Bairi

  • Publisher : Springer Nature
  • Release : 2020-09-28
  • Pages : 185
  • ISBN : 3030538214
  • Language : En, Es, Fr & De
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This book reviews the potential of next-generation sequencing (NGS) in research on and management of colorectal cancer (CRC), a leading cause of death worldwide and one of the most biologically and clinically heterogeneous cancers. It critically discusses findings from recent large-scale studies, clinical trials and meta-analyses and offers an introduction to the management of CRC in the era of precision medicine. In CRC, dozens of driver and passenger mutations are associated with the malignant transformation of epithelial cells. Consequently, the book discusses recent advances in our understanding of the genetics of CRC as a biomarker, the advent of NGS technologies in modern genomics, and the impact of NGS technology on the management of CRC. Furthermore, it highlights the potential of NGS in the context of liquid biopsy and single-cell sequencing in CRC, as well as its role in shedding light on the link between gut microbiota, immune-checkpoint blockade and CRC. The book concludes with a chapter on the limitations and cost-effectiveness of NGS in CRC. Given its scope, the book will appeal to all those interested in learning about the potential of NGS in advancing CRC research and patient care.

Explore the Dysbiosis of Gut Microbiota Along the Conventional Adenoma-Carcinoma Colorectal Cancer Pathway

Explore the Dysbiosis of Gut Microbiota Along the Conventional Adenoma-Carcinoma Colorectal Cancer Pathway
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2019
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Mechanisms Underlying Host-Microbiome Interactions in Pathophysiology of Human Diseases

Mechanisms Underlying Host-Microbiome Interactions in Pathophysiology of Human Diseases
A Book

by Jun Sun,Pradeep K. Dudeja

  • Publisher : Springer
  • Release : 2018-01-26
  • Pages : 381
  • ISBN : 149397534X
  • Language : En, Es, Fr & De
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Only recently have we begun to appreciate the role of microbiome in health and disease. Environmental factors and change of life style including diet significantly shape human microbiome that in turn appears to modify gut barrier function affecting nutrient & electrolyte absorption and inflammation. Approaches that can reverse the gut dysbiosis represent as reasonable and novel strategies for restoring the balance between host and microbes. In the book, we offer summary and discussion on the advances in understanding of pathophysiological mechanisms of microbial host interactions in human diseases. We will not only discuss intestinal bacterial community, but also viruses, fungi and oral microbiome. Microbiome studies will facilitate diagnosis, functional studies, drug development and personalized medicine. Thus, this book will further highlight the microbiome in the context of health and disease, focusing on mechanistic concepts that underlie the complex relationships between host and microbes.

Probiotic Research in Therapeutics

Probiotic Research in Therapeutics
Volume 1: Applications in Cancers and Immunological Diseases

by Indu Pal Kaur

  • Publisher : Springer Nature
  • Release : 2020
  • Pages : 373
  • ISBN : 9811582149
  • Language : En, Es, Fr & De
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The volume sheds new light on role of gut dysbiosis in cancer and immunological diseases and their clinical manifestations. Contributions in the volume discuss about the gut microbiota as a therapeutic target and the role of probiotics in its management. The volume explores application of probiotics in the treatment of various cancers viz. colorectal, gastric, lung, and breast cancer and immunological diseases. The volume comprises of chapters from expert contributors organized into various important themes which include, introduction, relationship between gut microbiota and disease condition, mechanisms involved, clinical and in vivo status, conclusion and future directions. This is a highly informative and carefully presented book, providing recent and innovative insight for scholars and researchers with an interest in probiotics and its applications in cancer and immunological diseases.

Gastrointestinal Diseases and Their Associated Infections

Gastrointestinal Diseases and Their Associated Infections
A Book

by Guy D. Eslick

  • Publisher : Elsevier Health Sciences
  • Release : 2019-01-17
  • Pages : 400
  • ISBN : 032354844X
  • Language : En, Es, Fr & De
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Many bacteria, viruses, protozoa, and fungi play key roles in the development of gastrointestinal diseases, and this practical reference brings you up to speed with this increasingly important area. Covering a broad range of GI diseases and cancers, this resource provides an expert overview of the field, ideal for all gastroenterologists and infectious disease physicians. Covers infections associated with gastroesophageal reflux disease and Barrett’s esophagus, gallbladder disease, acute pancreatitis, small intestinal bacterial overgrowth, irritable bowel syndrome, inflammatory bowel disease, appendicitis, Whipple Disease, Crohn’s Disease, and more. Discusses esophageal cancer, gastric cancer, cholangiocarcinoma, hepatocellular carcinoma, and colorectal cancer. Includes chapters on gut microbiome, fecal transplants, and the molecular pathgenesis of gastrointestinal infections. Consolidates today’s available information on this timely topic into a single convenient resource.

Cancer Research

Cancer Research
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2009-06
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Textbook of Veterinary Internal Medicine

Textbook of Veterinary Internal Medicine
Diseases of the Dog and the Cat

by Stephen J. Ettinger,Edward C. Feldman

  • Publisher : Unknown Publisher
  • Release : 2010
  • Pages : 2218
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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"Now in its 7th edition, this popular, must-have text remains the only encyclopedic resource for veterinary internal medical problems. The internationally acclaimed "gold standard" offers unparalleled coverage of pathophysiology, diagnosis, and treatment of diseases affecting dogs and cats, as well as the latest information on the genome, clinical genomics, euthanasia, innocent heart murmurs, hyperbaric medicine, home prepared and raw diets, obesity, botulism, artificial pacing of the heart, cancer vaccines, and more. The 7th edition combines the convenience of a two-volume printed textbook with the enhanced functionality of a regularly updated Expert Consult website that enables you to electronically search your entire book and study more efficiently. With instant access to the most reliable, up-to-date information available, you'll always be at the forefront of veterinary care!"--Jacket

Gut Microbiome and Its Impact on Health and Diseases

Gut Microbiome and Its Impact on Health and Diseases
A Book

by Debabrata Biswas,Shaik O. Rahaman

  • Publisher : Springer Nature
  • Release : 2020-08-27
  • Pages : 288
  • ISBN : 3030473848
  • Language : En, Es, Fr & De
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This book provides a comprehensive examination of the role of gut microbiome/microflora in nutrition, metabolism, disease prevention and health issues, including farm animal health and food value, and human gastrointestinal health and immunity. Indigenous microbiotas, particularly the gut microflora/microbiome, are an essential component in the modern concept of human and animal health. The diet and lifestyle of the host and environment have direct impact on gut microflora and the patterns of gut microbial colonization associated with health and diseases have been documented. Contributing authors cover the impact of gut microbiome in farm animal health, and explore the possibility of modulating the human gut microbiome with better animal products to prevent human diseases, including endemic and emerging diseases such as obesity, cancer and cardiac diseases. Dieting plan and control methods are examined, with attention paid to balance dieting with natural food and drink components. In addition, the role of gut microbiota in enteric microbial colonization and infections in farm animals is also discussed. The volume also explores the possibility of improving human health by modulating the microbiome with better food, including bio-active foods and appropriate forms of intake. Throughout the chapters, authors examine cutting edge research and technology, as well as future directions for better practices regarding emerging issues, such as the safety and production of organic food.

Probiotics and Bioactive Carbohydrates in Colon Cancer Management

Probiotics and Bioactive Carbohydrates in Colon Cancer Management
A Book

by Maya Raman,Padma Ambalam,Mukesh Doble

  • Publisher : Springer
  • Release : 2015-10-27
  • Pages : 124
  • ISBN : 8132225864
  • Language : En, Es, Fr & De
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This book describes the dietary habits (such as use of probiotics, synbiotics, prebiotics and dietary fiber) that could modify and reduce the risk of developing colorectal cancer (CRC). The book will be of practical and scientific use to academicians, research scholars, students, health professionals, nutritionists, etc. and could support the cause of preventing CRC by adopting smarter food habits. CRC is the third leading cause of death, in terms of both incidence and mortality, among men and women. Excess consumption of red and processed meat, roasted coffee, etc. have shown an increase in CRC, indicating that compounds formed in food containing free amino acids and sugars interact at elevated temperatures to form mutagens or carcinogens. Standard treatment options for CRC include invasive surgery and chemotherapy or radiation. Several lifestyle and dietary factors could prevent this ailment. Probiotics, prebiotics and synbiotics that are found in functional foods, health supplements and nutraceuticals and short chain fatty acids that are formed in the colon as a result of microbial fermentation of undigested bioactive carbohydrates by Bifidobacterium and Lactobacillus inhibit colonic epithelial cells and minimize inflammation, thereby exhibiting immunomodulatory effects. This book tries to address the novel unexplored benefits and mechanism of action of these functional foods.

Theranostics Approaches to Gastric and Colon Cancer

Theranostics Approaches to Gastric and Colon Cancer
A Book

by Ganji Seeta Rama Raju,L.V.K.S. Bhaskar

  • Publisher : Springer Nature
  • Release : 2020-03-04
  • Pages : 250
  • ISBN : 9811520178
  • Language : En, Es, Fr & De
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This book highlights the importance of understanding gastric and colon cancer metabolism in guiding diagnosis and drug discovery. It summarizes the correlation between adiponectin and matrix metalloproteinase with colorectal cancer. The book also evaluates the divergent role of hypoxia-inducible factor 1 in colorectal cancer growth and metastasis. After discussing the role of genetic polymorphisms in alcohol metabolizing enzymes and EPHX1 with the onset of colorectal cancer, it reviews the molecular mechanisms of chemoresistance in gastric cancer and novel therapeutic strategies to reverse the chemoresistance of tumors. In addition, the book explores the theranostic role of nanoparticles and therapeutic potential of phytochemicals with regard to colorectal cancer. Given its scope, the book offers a valuable guide for oncologists, academic researchers, pharmaceuticals practitioners, and students who are involved in research and treatment of cancer.

Microbiome and Cancer

Microbiome and Cancer
A Book

by Erle S. Robertson

  • Publisher : Springer
  • Release : 2019-02-20
  • Pages : 401
  • ISBN : 3030041557
  • Language : En, Es, Fr & De
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This book ventures into a new and exciting area of discovery that directly ties our current knowledge of cancer to the discovery of microorganisms associated with different types of cancers. Recent studies demonstrate that microorganisms are directly linked to the establishment of cancers and that they can also contribute to the initiation, as well as persistence of, the cancers. Microbiome and Cancer covers the current knowledge of microbiome and its association with human cancers. It provides important reading for novices, senior undergraduates in cancer and microbiology, graduate students, junior investigators, residents, fellows and established investigators in the fields of cancer and microbiology. We cover areas related to known, broad concepts in microbiology and how they can relate to the ongoing discoveries of the micro-environment and the changes in the metabolic and physiologic states in that micro-environment, which are important for the ongoing nurturing and survival of the poly-microbial content that dictates activities in that micro-environment. We cover the interactions of microorganisms associated with gastric carcinomas, which are important for driving this particular cancer. Additional areas include oral cancers, skin cancers, ovarian cancers, breast cancers, nasopharyngeal cancers, lung cancers, mesotheliomas, Hodgkin’s and non-Hodgkin’s lymphomas, glioblastoma multiforme, hepatocellular carcinomas, as well as the inflammatory response related to the infectious agents in cancers. This book covers the metabolic changes that occur because of infection and their support for development of cancers, chronic infection and development of therapeutic strategies for detection and control of the infection. The field of microbiome research has exploded over the last five years, and we are now understanding more and more about the context in which microorganisms can contribute to the onset of cancers in humans. The field of microbiome research has demonstrated that the human body has specific biomes for tissues and that changes in these biomes at the specific organ sites can result in disease. These changes can result in dramatic differences in metabolic shifts that, together with genetic mutations, will produce the perfect niche for establishment of the particular infection programmes in that organ site. We are just beginning to understand what those changes are and how they influence the disease state. Overall, we hope to bring together the varying degrees of fluctuations in the microbiome at the major organ sites and how these changes affect the normal cellular processes because of dysregulation, leading to proliferation of the associated tissues.

Novel Approaches to Colorectal Cancer

Novel Approaches to Colorectal Cancer
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2021-07-15
  • Pages : 312
  • ISBN : 9780128240786
  • Language : En, Es, Fr & De
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Novel Approaches to Colorectal Cancer, Volume 151 in the Advances in Cancer Research series, is composed of 11 reviews covering state-of-the-art research relating to the etiology, diagnosis, prevention and treatment of colorectal cancer. The book's chapters were written by recognized experts in the field, and include sections on molecular biomarkers in diagnosis and therapy, the interplay of diet, lifestyle, and the microbiome, early-age onset disease, mutational signature analysis, challenges in early detection, immunotherapy, organoid technology, the role of epigenetic alterations, disparities in minority populations, field carcinogenesis, and cancer as an evolutionary process. Each of these topics provides novel insights and concepts on various aspects of the nature of colorectal cancer, offering new opportunities for the management of a major source of cancer incidence and mortality. Provides information on the timely nature of the included topics, which represent the most current concepts and approaches in cancer research Offers outstanding and original reviews on colorectal cancer research Provides the authority and expertise of the authors, all of whom are highly recognized and conducting state-of-the-art investigations in cancer, with this release focusing on colorectal cancer

Intestinal Tumorigenesis

Intestinal Tumorigenesis
Mechanisms of Development & Progression

by Vincent W. Yang,Agnieszka B. Bialkowska

  • Publisher : Springer
  • Release : 2015-09-19
  • Pages : 445
  • ISBN : 3319199862
  • Language : En, Es, Fr & De
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This volume includes the information necessary to understand recent critical advances in the mechanisms of intestinal tumorigenesis and to comprehend the complexity of the process. The volume aims to entice new researchers to participate in relevant studies, and to provide a forum for discussion within the scientific community to shape future research in this field. Discoveries in intestinal tumorigenesis lead to further understanding of mechanisms involved in colon cancer. Additionally, advancements in techniques and methods open the doors for new approaches to better define the molecular and organismal mechanisms of intestinal tumorigenesis. Chapters are authored by widely published authorities in the field. Each year, there are close to 150,000 new cases of colorectal cancer, which results in approximately 50,000 deaths per year in the United States; these figures render colorectal cancer a significant health concern. Studies attempting to understand the mechanisms of development and progression of colorectal cancer have been ongoing for decades and each year brings new discoveries yielding a better comprehension of the underlying processes at work.