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Computational Immunology

Computational Immunology
Applications

by Shyamasree Ghosh

  • Publisher : CRC Press
  • Release : 2020-01-31
  • Pages : 172
  • ISBN : 1351023497
  • Language : En, Es, Fr & De
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Computational Immunology: Applications focuses on different mathematical models, statistical tools, techniques, and computational modelling that helps in understanding complex phenomena of the immune system and its biological functions. The book also focuses on the latest developments in computational biology in designing of drugs, targets, biomarkers for early detection and prognosis of a disease. It highlights the applications of computational methods in deciphering the complex processes of the immune system and its role in health and disease. This book discusses the most essential topics, including Next generation sequencing (NGS) and computational immunology Computational modelling and biology of diseases Drug designing Computation and identification of biomarkers Application in organ transplantation Application in disease detection and therapy Computational methods and applications in understanding of the invertebrate immune system S Ghosh is MSc, PhD, PGDHE, PGDBI, is PhD from IICB, CSIR, Kolkata, awarded the prestigious National Scholarship from the Government of India. She has worked and published extensively in glycobiology, sialic acids, immunology, stem cells and nanotechnology. She has authored several publications that include books and encyclopedia chapters in reputed journals and books.

Computational Immunology

Computational Immunology
Models and Tools

by Josep Bassaganya-Riera

  • Publisher : Academic Press
  • Release : 2015-10-21
  • Pages : 210
  • ISBN : 0128037156
  • Language : En, Es, Fr & De
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Computational Immunology: Models and Tools encompasses the methodological framework and application of cutting-edge tools and techniques to study immunological processes at a systems level, along with the concept of multi-scale modeling. The book's emphasis is on selected cases studies and application of the most updated technologies in computational modeling, discussing topics such as computational modeling and its usage in immunological research, bioinformatics infrastructure, ODE based modeling, agent based modeling, and high performance computing, data analytics, and multiscale modeling. There are also modeling exercises using recent tools and models which lead the readers to a thorough comprehension and applicability. The book is a valuable resource for immunologists, computational biologists, bioinformaticians, biotechnologists, and computer scientists, as well as all those who wish to broaden their knowledge in systems modeling. Offers case studies with different levels of complexity Provides a detailed view on cutting-edge tools for modeling that are useful to experimentalists with limited computational skills Explores the usage of simulation for hypothesis generation, helping the reader to understand the most valuable points on experimental setting

Methods and Applications of Computational Immunology

Methods and Applications of Computational Immunology
A Book

by Victor Greiff,Gur Yaari,Johannes Textor,Benny Chain

  • Publisher : Frontiers Media SA
  • Release : 2020-01-30
  • Pages : 329
  • ISBN : 2889633888
  • Language : En, Es, Fr & De
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Conceptual Modelling in Computational Immunology

Conceptual Modelling in Computational Immunology

by Martina Husáková

  • Publisher : Tomáš Bruckner
  • Release : 2015-09-10
  • Pages : 174
  • ISBN : 8087924029
  • Language : En, Es, Fr & De
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Computational immunology offers in silico strategies for understanding of complex processes occurring in the natural immune system of a living organism that are difficult to explore by traditional in vivo or in vitro techniques. The monograph introduces conceptual languages and approaches for modelling biological processes. The Agent Modelling Language is investigated for conceptualisation of immune processes. AML-based diagrams represent properties and processes occurring in a lymph node.

Proceedings of the ... Annual International Conference on Computational Biology

Proceedings of the ... Annual International Conference on Computational Biology
RECOMB ...

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2002
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Computational Biology and Applied Bioinformatics

Computational Biology and Applied Bioinformatics
A Book

by Heitor Lopes,Leonardo Magalhães Cruz

  • Publisher : BoD – Books on Demand
  • Release : 2011-09-02
  • Pages : 458
  • ISBN : 9533076291
  • Language : En, Es, Fr & De
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Nowadays it is difficult to imagine an area of knowledge that can continue developing without the use of computers and informatics. It is not different with biology, that has seen an unpredictable growth in recent decades, with the rise of a new discipline, bioinformatics, bringing together molecular biology, biotechnology and information technology. More recently, the development of high throughput techniques, such as microarray, mass spectrometry and DNA sequencing, has increased the need of computational support to collect, store, retrieve, analyze, and correlate huge data sets of complex information. On the other hand, the growth of the computational power for processing and storage has also increased the necessity for deeper knowledge in the field. The development of bioinformatics has allowed now the emergence of systems biology, the study of the interactions between the components of a biological system, and how these interactions give rise to the function and behavior of a living being. This book presents some theoretical issues, reviews, and a variety of bioinformatics applications. For better understanding, the chapters were grouped in two parts. In Part I, the chapters are more oriented towards literature review and theoretical issues. Part II consists of application-oriented chapters that report case studies in which a specific biological problem is treated with bioinformatics tools.

Bioinformatics and Computational Biology in Drug Discovery and Development

Bioinformatics and Computational Biology in Drug Discovery and Development
A Book

by William T. Loging

  • Publisher : Cambridge University Press
  • Release : 2016-02-29
  • Pages : 248
  • ISBN : 0521768004
  • Language : En, Es, Fr & De
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A comprehensive overview of the use of computational biology approaches in the drug discovery and development process.

Killer Cell Dynamics

Killer Cell Dynamics
Mathematical and Computational Approaches to Immunology

by Dominik Wodarz

  • Publisher : Springer Science & Business Media
  • Release : 2007-04-05
  • Pages : 220
  • ISBN : 0387687335
  • Language : En, Es, Fr & De
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This book reviews how mathematical and computational approaches can be useful to help us understand how killer T-cell responses work to fight viral infections. It also demonstrates, in a writing style that exemplifies the point, that such mathematical and computational approaches are most valuable when coupled with experimental work through interdisciplinary collaborations. Designed to be useful to immunoligists and viroligists without extensive computational background, the book covers a broad variety of topics, including both basic immunological questions and the application of these insights to the understanding and treatment of pathogenic human diseases.

Encyclopedia of Bioinformatics and Computational Biology

Encyclopedia of Bioinformatics and Computational Biology
ABC of Bioinformatics

by Anonim

  • Publisher : Elsevier
  • Release : 2018-08-21
  • Pages : 3284
  • ISBN : 0128114320
  • Language : En, Es, Fr & De
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Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

The Journal of Immunology

The Journal of Immunology
Official Journal of the American Association of Immunologists

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Complex Systems and Computational Biology Approaches to Acute Inflammation

Complex Systems and Computational Biology Approaches to Acute Inflammation
A Framework for Model-based Precision Medicine

by Yoram Vodovotz,Gary An

  • Publisher : Springer
  • Release : 2020-11-05
  • Pages : 312
  • ISBN : 9783030565091
  • Language : En, Es, Fr & De
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This second edition expands upon and updates the vital research covered in its predecessor, by presenting state-of-the-art multidisciplinary and systems-oriented approaches to complex diseases arising from and driven by the acute inflammatory response. The chapters in this volume provide an introduction to different types of computational modeling, and how these methods can be applied to specific inflammatory diseases, with a focus on providing readers a roadmap for integrating advanced mathematical and computational techniques with traditional experimental methods. In this second edition, we cover both well-established and emerging modeling methods, especially state-of-the-art machine learning approaches and the integration of data-driven and mechanistic modeling. This volume introduces the concept of Model-based Precision Medicine as an alternative approach to the current view of Precision Medicine, based on leveraging mechanistic computational modeling to decrease cost while increasing the information value of the data being obtained. By presenting the role of computational modeling as an integrated component of the research process, Complex Systems and Computational Biology Approaches to Acute Inflammation: A Framework for Model-based Precision Medicine offers a window into the recent past, the present, and the future of computationally-augmented biomedical research.

Mathematical, Computational and Experimental T Cell Immunology

Mathematical, Computational and Experimental T Cell Immunology
A Book

by Carmen Molina-París

  • Publisher : Springer Nature
  • Release : 2021
  • Pages : 329
  • ISBN : 3030572048
  • Language : En, Es, Fr & De
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Proceedings of the Sixth Annual International Conference on Computational Biology

Proceedings of the Sixth Annual International Conference on Computational Biology
A Book

by Gene Myers,International Conference on Computational Biology

  • Publisher : Unknown Publisher
  • Release : 2002
  • Pages : 331
  • ISBN : 9781581134988
  • Language : En, Es, Fr & De
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Dictionary of Bioinformatics and Computational Biology

Dictionary of Bioinformatics and Computational Biology
A Book

by John M. Hancock,Marketa J. Zvelebil

  • Publisher : Wiley-Liss
  • Release : 2004
  • Pages : 636
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Publisher Description

Mathematical Reviews

Mathematical Reviews
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2003
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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New Scientist

New Scientist
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Directory of Pathology Training Programs

Directory of Pathology Training Programs
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Describes training facilities, residencies, remuneration, application requirements, and faculty at approved programs for anatomic and clinical pathology in the U.S. and Canada. Also includes coverage of fellowships and postgraduate opportunities for training.

International Research Centers Directory

International Research Centers Directory
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2009
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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"A world guide to government, university, independent nonprofit, and commercial research and development centers, institutes, laboratories, bureaus, test facilities, experiment stations, and data collection and analysis centers, as well as foundations, councils and other organizations which support research," [1992/93-].

Systems Immunology

Systems Immunology
An Introduction to Modeling Methods for Scientists

by Jayajit Das,Ciriyam Jayaprakash

  • Publisher : CRC Press
  • Release : 2018-09-03
  • Pages : 334
  • ISBN : 1498717411
  • Language : En, Es, Fr & De
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"Taken together, the body of information contained in this book provides readers with a bird’s-eye view of different aspects of exciting work at the convergence of disciplines that will ultimately lead to a future where we understand how immunity is regulated, and how we can harness this knowledge toward practical ends that reduce human suffering. I commend the editors for putting this volume together." –Arup K. Chakraborty, Robert T. Haslam Professor of Chemical Engineering, and Professor of Physics, Chemistry, and Biological Engineering, Massachusetts Institute of Technology, Cambridge, USA New experimental techniques in immunology have produced large and complex data sets that require quantitative modeling for analysis. This book provides a complete overview of computational immunology, from basic concepts to mathematical modeling at the single molecule, cellular, organism, and population levels. It showcases modern mechanistic models and their use in making predictions, designing experiments, and elucidating underlying biochemical processes. It begins with an introduction to data analysis, approximations, and assumptions used in model building. Core chapters address models and methods for studying immune responses, with fundamental concepts clearly defined. Readers from immunology, quantitative biology, and applied physics will benefit from the following: Fundamental principles of computational immunology and modern quantitative methods for studying immune response at the single molecule, cellular, organism, and population levels. An overview of basic concepts in modeling and data analysis. Coverage of topics where mechanistic modeling has contributed substantially to current understanding. Discussion of genetic diversity of the immune system, cell signaling in the immune system, immune response at the cell population scale, and ecology of host-pathogen interactions.

Computational Molecular Biology

Computational Molecular Biology
An Introduction

by Peter Clote,Peter G.. Clote,Rolf Backofen

  • Publisher : Wiley-Blackwell
  • Release : 2000-10-03
  • Pages : 286
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Recently molecular biology has undergone unprecedented development generating vast quantities of data needing sophisticated computational methods for analysis, processing and archiving. This requirement has given birth to the truly interdisciplinary field of computational biology, or bioinformatics, a subject reliant on both theoretical and practical contributions from statistics, mathematics, computer science and biology. Provides the background mathematics required to understand why certain algorithms work Guides the reader through probability theory, entropy and combinatorial optimization In-depth coverage of molecular biology and protein structure prediction Includes several less familiar algorithms such as DNA segmentation, quartet puzzling and DNA strand separation prediction Includes class tested exercises useful for self-study Source code of programs available on a Web site Primarily aimed at advanced undergraduate and graduate students from bioniformatics, computer science, statistics, mathematics and the biological sciences, this text will also interest researchers from these fields.