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Computational Neuroscience in Epilepsy

Computational Neuroscience in Epilepsy
A Book

by Ivan Soltesz,Kevin Staley

  • Publisher : Academic Press
  • Release : 2011-09-02
  • Pages : 624
  • ISBN : 9780080559537
  • Language : En, Es, Fr & De
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Epilepsy is a neurological disorder that affects millions of patients worldwide and arises from the concurrent action of multiple pathophysiological processes. The power of mathematical analysis and computational modeling is increasingly utilized in basic and clinical epilepsy research to better understand the relative importance of the multi-faceted, seizure-related changes taking place in the brain during an epileptic seizure. This groundbreaking book is designed to synthesize the current ideas and future directions of the emerging discipline of computational epilepsy research. Chapters address relevant basic questions (e.g., neuronal gain control) as well as long-standing, critically important clinical challenges (e.g., seizure prediction). Computational Neuroscience in Epilepsy should be of high interest to a wide range of readers, including undergraduate and graduate students, postdoctoral fellows and faculty working in the fields of basic or clinical neuroscience, epilepsy research, computational modeling and bioengineering. Covers a wide range of topics from molecular to seizure predictions and brain implants to control seizures Contributors are top experts at the forefront of computational epilepsy research Chapter contents are highly relevant to both basic and clinical epilepsy researchers

Bundle for Epilepsy Researchers

Bundle for Epilepsy Researchers
A Book

by Ruben Kuzniecky,Asla Pitknen,Ivan Soltesz

  • Publisher : Academic Press
  • Release : 2008-10-03
  • Pages : 129
  • ISBN : 9780123748690
  • Language : En, Es, Fr & De
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Combining three essential Academic Press books, this bundle provides reference information for epilepsy researchers at a great price. Magnetic Resonance in Epilepsy is an in-depth look at the advances in imaging techology as applied to epilepsy research. Models of Seizures and Epilepsy speaks to the needs of both basic neuroscientists and clinical neurologists, in understanding the pathophysiology of seizures and the epilepsies and predicting the clinical effectiveness of antiepileptic treatments. Computational Neuroscience in Epilepsy is the first-ever book solely dedicated to the emerging discipline of computational epilepsy research.

Computational Neurology and Psychiatry

Computational Neurology and Psychiatry
A Book

by Péter Érdi,Basabdatta Sen Bhattacharya,Amy L. Cochran

  • Publisher : Springer
  • Release : 2017-01-25
  • Pages : 448
  • ISBN : 3319499599
  • Language : En, Es, Fr & De
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This book presents the latest research in computational methods for modeling and simulating brain disorders. In particular, it shows how mathematical models can be used to study the relationship between a given disorder and the specific brain structure associated with that disorder. It also describes the emerging field of computational psychiatry, including the study of pathological behavior due to impaired functional connectivity, pathophysiological activity, and/or aberrant decision-making. Further, it discusses the data analysis techniques that will be required to analyze the increasing amount of data being generated about the brain. Lastly, the book offers some tips on the application of computational models in the field of quantitative systems pharmacology. Mainly written for computational scientists eager to discover new application fields for their model, this book also benefits neurologists and psychiatrists wanting to learn about new methods.

Computational Neuroscience

Computational Neuroscience
Trends in Research, 1997

by James M. Bower

  • Publisher : Springer Science & Business Media
  • Release : 2013-06-29
  • Pages : 961
  • ISBN : 1475798008
  • Language : En, Es, Fr & De
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This volume includes papers presented at the Fifth Annual Computational Neurosci ence meeting (CNS*96) held in Boston, Massachusetts, July 14 - 17, 1996. This collection includes 148 of the 234 papers presented at the meeting. Acceptance for mceting presenta tion was based on the peer review of preliminary papers originally submitted in May of 1996. The papers in this volume represent final versions of this work submitted in January of 1997. As represented by this volume, computational neuroscience continues to expand in quality, size and breadth of focus as increasing numbers of neuroscientists are taking a computational approach to understanding nervous system function. Defining computa tional neuroscience as the exploration of how brains compute, it is clear that there is al most no subject or area of modern neuroscience research that is not appropriate for computational studies. The CNS meetings as well as this volume reflect this scope and di versity.

Neurobiology of Epilepsy

Neurobiology of Epilepsy
From Genes to Networks

by Anonim

  • Publisher : Academic Press
  • Release : 2016-06-20
  • Pages : 250
  • ISBN : 0444636455
  • Language : En, Es, Fr & De
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Neurobiology of Epilepsy: From Genes to Networks is the latest volume in the Progress in Brain Research series that focuses on new trends and developments. This established international series examines major areas of basic and clinical research within the neurosciences, as well as popular and emerging subfields. Explores new trends and developments in the neurobiology of Epilepsy Enhances the literature of neuroscience by further expanding the established, ongoing international series Progress in Brain Research Examines major areas of basic and clinical research within the field

Jasper's Basic Mechanisms of the Epilepsies

Jasper's Basic Mechanisms of the Epilepsies
A Book

by Herbert Henri Jasper

  • Publisher : OUP USA
  • Release : 2012-06-29
  • Pages : 1199
  • ISBN : 0199746540
  • Language : En, Es, Fr & De
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Prev. ed.: Jasper's basic mechanisms of the epilepsies / editors, Antonio V. Delgado-Escueta ... [et. al.]. 3rd. ed. c1999.

Validating Neuro-Computational Models of Neurological and Psychiatric Disorders

Validating Neuro-Computational Models of Neurological and Psychiatric Disorders
A Book

by Basabdatta Sen Bhattacharya,Fahmida N. Chowdhury

  • Publisher : Springer
  • Release : 2015-10-30
  • Pages : 315
  • ISBN : 3319200372
  • Language : En, Es, Fr & De
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This book is a collection of articles by leading researchers working at the cutting edge of neuro-computational modelling of neurological and psychiatric disorders. Each article contains model validation techniques used in the context of the specific problem being studied. Validation is essential for neuro-inspired computational models to become useful tools in the understanding and treatment of disease conditions. Currently, the immense diversity in neuro-computational modelling approaches for investigating brain diseases has created the need for a structured and coordinated approach to benchmark and standardise validation methods and techniques in this field of research. This book serves as a step towards a systematic approach to validation of neuro-computational models used for studying brain diseases and should be useful for all neuro-computational modellers.

Models of Seizures and Epilepsy

Models of Seizures and Epilepsy
A Book

by Asla Pitkänen,Paul Buckmaster, DVM, PhD,Aristea S Galanopoulou,Solomon L. Moshé

  • Publisher : Academic Press
  • Release : 2017-06-14
  • Pages : 1178
  • ISBN : 012804067X
  • Language : En, Es, Fr & De
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Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. Provides a comprehensive reference detailing animal models of epilepsy and seizure Offers insights on the use of novel technologies that can be applied in experimental epilepsy research Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments

Biocomputing

Biocomputing
A Book

by Panos M. Pardalos,J.C. Principe

  • Publisher : Springer Science & Business Media
  • Release : 2013-12-01
  • Pages : 264
  • ISBN : 1461302595
  • Language : En, Es, Fr & De
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In the quest to understand and model the healthy or sick human body, re searchers and medical doctors are utilizing more and more quantitative tools and techniques. This trend is pushing the envelope of a new field we call Biomedical Computing, as an exciting frontier among signal processing, pattern recognition, optimization, nonlinear dynamics, computer science and biology, chemistry and medicine. A conference on Biocomputing was held during February 25-27, 2001 at the University of Florida. The conference was sponsored by the Center for Applied Optimization, the Computational Neuroengineering Center, the Biomedical En gineering Program (through a Whitaker Foundation grant), the Brain Institute, the School of Engineering, and the University of Florida Research & Graduate Programs. The conference provided a forum for researchers to discuss and present new directions in Biocomputing. The well-attended three days event was highlighted by the presence of top researchers in the field who presented their work in Biocomputing. This volume contains a selective collection of ref ereed papers based on talks presented at this conference. You will find seminal contributions in genomics, global optimization, computational neuroscience, FMRI, brain dynamics, epileptic seizure prediction and cancer diagnostics. We would like to take the opportunity to thank the sponsors, the authors of the papers, the anonymous referees, and Kluwer Academic Publishers for making the conference successful and the publication of this volume possible. Panos M. Pardalos and Jose C.

Reproducibility and Rigour in Computational Neuroscience

Reproducibility and Rigour in Computational Neuroscience
A Book

by Sharon Crook,Andrew P. Davison,Robert Andrew McDougal,Hans Ekkehard Plesser

  • Publisher : Frontiers Media SA
  • Release : 2020-07-09
  • Pages : 129
  • ISBN : 2889638383
  • Language : En, Es, Fr & De
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Epilepsy

Epilepsy
Mechanisms, Models, and Translational Perspectives

by Jong Rho,Raman Sankar,Carl E. Stafstrom

  • Publisher : CRC Press
  • Release : 2010-06-18
  • Pages : 684
  • ISBN : 1420085603
  • Language : En, Es, Fr & De
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Epilepsy has afflicted humankind throughout recorded history; yet, it is only in the last half-century, that significant progress has been made in our basic understanding of the epileptic brain. Pivotal advances in drug development and surgical techniques, as well as the emergence of innovative approaches such as electrical stimulation of the nervo

Epilepsy

Epilepsy
The Intersection of Neurosciences, Biology, Mathematics, Engineering, and Physics

by Ivan Osorio,Hitten P. Zaveri,Mark G. Frei,Susan Arthurs

  • Publisher : CRC Press
  • Release : 2016-04-19
  • Pages : 578
  • ISBN : 9781439838860
  • Language : En, Es, Fr & De
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Epilepsy, one of the most prevalent neurological disorders, affects approximately 1% (greater than 60 million) of the world's population. In an estimated 20 million of these patients, seizures are not controlled even by multiple anti-seizure drugs, and are extremely difficult to predict. Epilepsy: The Intersection of Neurosciences, Biology, Mathematics, Engineering, and Physics seamlessly brings together the neurosciences, mathematics, computational sciences, engineering, physics, and clinical epileptology to present to readers a highly didactic, integrated, clear and practically useful knowledge base and research directions. Laying out the foundations of signal analysis, data conditioning, linear and non-linear analysis, introduction to dynamical systems and fundamental anatomical and neurophysiological concepts, this book: Introduces non-physicians to language and concepts necessary to establish a meaningful dialog with epileptologists Introduces physicians to dynamical theory and signal processing without which interdisciplinary collaborations would not be productive Mines knowledge from fields devoted to the investigation of aperiodic paroxysmal relaxation phenomena, such as earthquakes, which bear dynamical similarities with epilepsy, so as to lay the proper scientific foundations for epileptology and foster much needed therapeutic advances efficiently Reviews spatiotemporal behavior of seizures, mechanisms of epileptogenesis and ictogenesis as well as of seizure control and ancillary technology Calls attention to nocturnal frontal lobe epilepsy as a potentially fruitful paradigm for advancing seizure prediction. Of all neurological disorders, epilepsy demands of investigators the broadest and deepest knowledge of dynamical, control, and system theories, knowledge that cannot be amassed without possessing a certain level of sophistication in relevant areas of neurosciences, physics, mathematics, and engineering. Narrowing the inescapable cultural chasm that commonly fragments multidisciplinary efforts, this book captures and enriches the burgeoning interdisciplinary synergism in the nascent field of dynamical epileptology.

Computational Neuroscience: Trends in Research 2003

Computational Neuroscience: Trends in Research 2003
A Book

by E. De Schutter

  • Publisher : Elsevier
  • Release : 2003-07-04
  • Pages : 997
  • ISBN : 9780444513830
  • Language : En, Es, Fr & De
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This volume includes papers originally presented at the 11th annual Computational Neuroscience Meeting (CNS 02) held in July 2002 at the Congress Plaza Hotel & Convention Center in Chicago, Illinois, USA. The CNS meetings bring together computational neuroscientists representing many different fields and backgrounds as well as many different experimental preparations and theoretical approaches. The papers published here range from pure experimental neurobiology, to neuro-ethology, mathematics, physics, and engineering. In all cases the research described is focused on understanding how nervous systems compute. The actual subjects of the research include a highly diverse number of preparations, modeling approaches and analysis techniques. Accordingly, this volume reflects the breadth and depth of current research in computational neuroscience taking place throughout the world.

Advanced Therapy in Epilepsy

Advanced Therapy in Epilepsy
A Book

by James W. Wheless,James Willmore,Roger A. Brumback

  • Publisher : PMPH-USA
  • Release : 2009
  • Pages : 478
  • ISBN : 9781607950042
  • Language : En, Es, Fr & De
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The social and health consequences of epilepsy on the lives of patients are enormous, and, although diagnosis and providing effective treatments remain challenging, the last decade has brought significant progress. Advanced Therapy in Epilepsy offers a comprehensive review of epilepsy in all of its manifestations: its history, neurophysiology, and newly available diagnostic tools and treatments, including neuroimaging, epileptic drug treatments, immunotherapy, dietary therapy, and surgery. Discussions of psychiatric illness and the social and legal issues associated with epilepsy complete the volume. Because epilepsy affects individuals across the human lifespan from infancy to old age, this book will be a valuable resource to any physician engaged in the care of patients with seizures or epilepsy. An enormous amount of information is presented concisely and clearly, allowing for a quick grasp of the material covered. Fifty-eight chapters have been contributed by authors who have demonstrated expertise in each area of concern. Throughout this textbook the appreciation of the editors and authors for the courage and humanity of their patients informs their approach to this ubiquitous and challenging disorder. Key Features Enormous amount of useful data at very affordable price Coverage of associated co-morbid conditions. Tie-in with other illnesses and recommended treatment (i.e. depression, Alzheimer's disease, stroke, head trauma). CD with videos of the various seizure types, and surgeries Antiepileptic drugs overview: Specific review of each and every drug available today and how to use each to treat specific aspects of epilepsy. Neuroimaging in Epilepsy/MEG and Clinical Neurophysiology. State-of-the-art review of imaging and diagnostic modalities. Easy to read and use to indicate proper application in evaluation and treatment.

Computational Models of Brain and Behavior

Computational Models of Brain and Behavior
A Book

by Ahmed A. Moustafa

  • Publisher : John Wiley & Sons
  • Release : 2017-11-13
  • Pages : 584
  • ISBN : 1119159067
  • Language : En, Es, Fr & De
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A comprehensive Introduction to the world of brain and behavior computational models This book provides a broad collection of articles covering different aspects of computational modeling efforts in psychology and neuroscience. Specifically, it discusses models that span different brain regions (hippocampus, amygdala, basal ganglia, visual cortex), different species (humans, rats, fruit flies), and different modeling methods (neural network, Bayesian, reinforcement learning, data fitting, and Hodgkin-Huxley models, among others). Computational Models of Brain and Behavior is divided into four sections: (a) Models of brain disorders; (b) Neural models of behavioral processes; (c) Models of neural processes, brain regions and neurotransmitters, and (d) Neural modeling approaches. It provides in-depth coverage of models of psychiatric disorders, including depression, posttraumatic stress disorder (PTSD), schizophrenia, and dyslexia; models of neurological disorders, including Alzheimer’s disease, Parkinson’s disease, and epilepsy; early sensory and perceptual processes; models of olfaction; higher/systems level models and low-level models; Pavlovian and instrumental conditioning; linking information theory to neurobiology; and more. Covers computational approximations to intellectual disability in down syndrome Discusses computational models of pharmacological and immunological treatment in Alzheimer's disease Examines neural circuit models of serotonergic system (from microcircuits to cognition) Educates on information theory, memory, prediction, and timing in associative learning Computational Models of Brain and Behavior is written for advanced undergraduate, Master's and PhD-level students—as well as researchers involved in computational neuroscience modeling research.

Oxford Textbook of Epilepsy and Epileptic Seizures

Oxford Textbook of Epilepsy and Epileptic Seizures
A Book

by Simon Shorvon,Renzo Guerrini,Mark Cook,Samden Lhatoo

  • Publisher : Oxford University Press
  • Release : 2012-12-20
  • Pages : 400
  • ISBN : 0199659044
  • Language : En, Es, Fr & De
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Part of the Oxford Textbooks in Clinical Neurology (OTCN) series, this volume covers the scientific basis, clinical diagnosis, and treatment of epilepsy and epileptic seizures, and is complemented by an online edition.

The Treatment of Epilepsy

The Treatment of Epilepsy
A Book

by Simon Shorvon,Emilio Perucca,Jerome Engel, Jr.

  • Publisher : John Wiley & Sons
  • Release : 2015-09-23
  • Pages : 1072
  • ISBN : 111893699X
  • Language : En, Es, Fr & De
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Highly Commended at the British Medical Association Book Awards 2016 The Treatment of Epilepsy, fourth edition, is a comprehensive reference and clinical guide to the pharmacological, medical and surgical options available in the treatment of epilepsy. The text is compiled by a group of internationally renowned editors and contributors and is now in full color and extensively illustrated The first two sections cover the background to, and principles of, treatment in different clinical situations Section three comprises a series of systematic reviews of contemporary drug therapy, devoting one chapter to each anti-epileptic drug and covering all clinically-relevant aspects Section four focuses on the surgical options, devoting individual chapters to each of the modalities of presurgical assessment and to each surgical operation or approach This 4th edition is extensively revised incorporating the many recent developments in therapy, and comprises 81 chapters from world experts from 18 countries

Cognitive and Computational Neuroscience

Cognitive and Computational Neuroscience
Principles, Algorithms and Applications

by Seyyed Abed Hosseini

  • Publisher : BoD – Books on Demand
  • Release : 2018-05-30
  • Pages : 104
  • ISBN : 1789231884
  • Language : En, Es, Fr & De
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The book "Cognitive and Computational Neuroscience - Principles, Algorithms and Applications" will answer the following question and statements: System-level neural modeling: what and why? We know a lot about the brain! Need to integrate data: molecular/cellular/system levels. Complexity: need to abstract away higher-order principles. Models are tools to develop explicit theories, constrained by multiple levels (neural and behavioral). Key: models (should) make novel testable predictions on both neural and behavioral levels. Models are useful tools for guiding experiments. The hope is that the information provided in this book will trigger new researches that will help to connect basic neuroscience to clinical medicine.

Advances in Cognitive Neurodynamics (V)

Advances in Cognitive Neurodynamics (V)
Proceedings of the Fifth International Conference on Cognitive Neurodynamics - 2015

by Rubin Wang,Xiaochuan Pan

  • Publisher : Springer
  • Release : 2016-01-29
  • Pages : 872
  • ISBN : 981100207X
  • Language : En, Es, Fr & De
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This proceedings contains articles submitted to the fifth International Conference on Cognitive Neurodynamics (ICCN2015). In ICCN2015, twelve invited plenary lectures were presented by the leading scientists in their respective research fields. More than 15 mini-symposiums are organized by specialists with topics covering: motor control and learning, dynamic coding in distributed neural circuits, dynamics of firing patterns and synchronization in neuronal systems, information and signal processing techniques in neurotechnology, neural oscillations and synaptic plasticity in the hippocampus, new perspective on model-based vs. model-free brain process, neural mechanisms of internal switching, neuroinformation computation, neural model and dynamics, imaging human cognitive networks, neuroinformatics, neuroergonomics & neuroengineering, dynamic brain for communication, visual information processing and functional imaging and neural mechanisms of language processing. All articles are peer-reviewed. The ICCN is a series conference held every two years since 2007.

Connectomics

Connectomics
Applications to Neuroimaging

by Brent C. Munsell,Guorong Wu,Leonardo Bonilha,Paul Laurienti

  • Publisher : Academic Press
  • Release : 2018-09-08
  • Pages : 233
  • ISBN : 0128138394
  • Language : En, Es, Fr & De
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Connectomics: Applications to Neuroimaging is unique in presenting the frontier of neuro-applications using brain connectomics techniques. The book describes state-of-the-art research that applies brain connectivity analysis techniques to a broad range of neurological and psychiatric disorders (Alzheimer’s, epilepsy, stroke, autism, Parkinson’s, drug or alcohol addiction, depression, bipolar, and schizophrenia), brain fingerprint applications, speech-language assessments, and cognitive assessment. With this book the reader will learn: Basic mathematical principles underlying connectomics How connectomics is applied to a wide range of neuro-applications What is the future direction of connectomics techniques. This book is an ideal reference for researchers and graduate students in computer science, data science, computational neuroscience, computational physics, or mathematics who need to understand how computational models derived from brain connectivity data are being used in clinical applications, as well as neuroscientists and medical researchers wanting an overview of the technical methods. Features: Combines connectomics methods with relevant and interesting neuro-applications Covers most of the hot topics in neuroscience and clinical areas Appeals to researchers in a wide range of disciplines: computer science, engineering, data science, mathematics, computational physics, computational neuroscience, as well as neuroscience, and medical researchers interested in the technical methods of connectomics Combines connectomics methods with relevant and interesting neuro-applications Presents information that will appeal to researchers in a wide range of disciplines, including computer science, engineering, data science, mathematics, computational physics, computational neuroscience, and more Includes a mathematics primer that formulates connectomics from an applied point-of-view, thus avoiding difficult to understand theoretical perspective Lists publicly available neuro-imaging datasets that can be used to construct structural and functional connectomes