Download Conceptual Breakthroughs in the Evolutionary Biology of Aging Ebook PDF

Conceptual Breakthroughs in the Evolutionary Biology of Aging

Conceptual Breakthroughs in the Evolutionary Biology of Aging
A Book

by Kenneth R. Arnold,Michael R. Rose

  • Publisher : Academic Press
  • Release : 2021-06-15
  • Pages : 296
  • ISBN : 9780128215456
  • Language : En, Es, Fr & De
GET BOOK

Conceptual Breakthroughs in the Evolutionary Biology of Aging continues the innovative Conceptual Breakthroughs series by providing a comprehensive outline of the major breakthroughs that built the evolutionary biology of aging as a leading scientific field. Following the evolutionary study of aging from its humble origins to the present, the book's chapters treat the field's breakthroughs one at a time. Users will find a concise and accessible analysis of the science of aging viewed through an evolutionary lens. Building upon widely-cited studies conducted by author Michael Rose, this book covers 30 subsequent years of growth and development within the field. The book highlights key publications for those who are not experts in the field, providing an important resource for researchers. Given the prevailing interest in changing the aging process dramatically, it is a powerful tool for readers who have a vested interest in understanding its causes and future control measures. Reviews cell-molecular theories of aging in the light of evolutionary biology Offers an evolutionary analysis of prospects for mitigating aging not commonly discussed within private and public sectors Provides readers with a radically different perspective on contemporary biological gerontology, specifically through the lens of evolutionary biology

Conceptual Breakthroughs in Evolutionary Genetics

Conceptual Breakthroughs in Evolutionary Genetics
A Brief History of Shifting Paradigms

by John C. Avise

  • Publisher : Academic Press
  • Release : 2014-01-18
  • Pages : 184
  • ISBN : 0124202373
  • Language : En, Es, Fr & De
GET BOOK

Conceptual Breakthroughs in Evolutionary Genetics is a pithy, lively book occupying a special niche—the conceptual history of evolutionary genetics— not inhabited by any other available treatment. Written by a world-leading authority in evolutionary genetics, this work encapsulates and ranks 70 of the most significant paradigm shifts in evolutionary biology and genetics during the century-and-a-half since Darwin and Mendel. The science of evolutionary genetics is central to all of biology, but many students and other practitioners have little knowledge of its historical roots and conceptual developments. This book fills that knowledge gap in a thought-provoking and readable format. This fascinating chronological journey along the many conceptual pathways to our modern understanding of evolutionary and genetic principles is a wonderful springboard for discussions in undergraduate or graduate seminars in evolutionary biology and genetics. But more than that, anyone interested in the history and philosophy of science will find much of value between its covers. Provides a relative ranking of 70 seminal breakthroughs and paradigm shifts in the field of evolutionary biology and genetics Modular format permits ready access to each described subject Historical overview of a field whose concepts are central to all of biology and relevant to a broad audience of biologists, science historians, and philosophers of science Extensively cross-referenced with a guide to landmark papers and books for each topic

Evolutionary Biology of Aging

Evolutionary Biology of Aging
A Book

by Michael R. Rose

  • Publisher : Oxford University Press on Demand
  • Release : 1991
  • Pages : 221
  • ISBN : 0195095308
  • Language : En, Es, Fr & De
GET BOOK

In this provocative book on the process of growing old, Michael Rose goes right to the heart of the fundamental "unsolved problem" of biology. Why do we grow old? The proposed theory is that to understand aging we must understand its evolution; only then do its taxonomic distribution and its genetic and physiological mechanisms become intelligible. Evidence is produced from the fields of cell biology, physiology, and gerontology.

Conceptual Breakthroughs in Evolutionary Ecology

Conceptual Breakthroughs in Evolutionary Ecology
A Book

by Laurence Mueller

  • Publisher : Academic Press
  • Release : 2019-11-25
  • Pages : 204
  • ISBN : 0128160144
  • Language : En, Es, Fr & De
GET BOOK

Although biologists recognize evolutionary ecology by name, many only have a limited understanding of its conceptual roots and historical development. Conceptual Breakthroughs in Evolutionary Ecology fills that knowledge gap in a thought-provoking and readable format. Written by a world-renowned evolutionary ecologist, this book embodies a unique blend of expertise in combining theory and experiment, population genetics and ecology. Following an easily-accessible structure, this book encapsulates and chronologizes the history behind evolutionary ecology. It also focuses on the integration of age-structure and density-dependent selection into an understanding of life-history evolution. Covers over 60 seminal breakthroughs and paradigm shifts in the field of evolutionary biology and ecology Modular format permits ready access to each described subject Historical overview of a field whose concepts are central to all of biology and relevant to a broad audience of biologists, science historians, and philosophers of science

Conceptual Breakthroughs in Evolutionary Ecology

Conceptual Breakthroughs in Evolutionary Ecology
A Book

by Laurence Mueller

  • Publisher : Academic Press
  • Release : 2019-11-25
  • Pages : 204
  • ISBN : 0128160144
  • Language : En, Es, Fr & De
GET BOOK

Although biologists recognize evolutionary ecology by name, many only have a limited understanding of its conceptual roots and historical development. Conceptual Breakthroughs in Evolutionary Ecology fills that knowledge gap in a thought-provoking and readable format. Written by a world-renowned evolutionary ecologist, this book embodies a unique blend of expertise in combining theory and experiment, population genetics and ecology. Following an easily-accessible structure, this book encapsulates and chronologizes the history behind evolutionary ecology. It also focuses on the integration of age-structure and density-dependent selection into an understanding of life-history evolution. Covers over 60 seminal breakthroughs and paradigm shifts in the field of evolutionary biology and ecology Modular format permits ready access to each described subject Historical overview of a field whose concepts are central to all of biology and relevant to a broad audience of biologists, science historians, and philosophers of science

Evolutionary Genetics

Evolutionary Genetics
Concepts and Case Studies

by Charles W. Fox,Jason B. Wolf

  • Publisher : Oxford University Press
  • Release : 2006-04-27
  • Pages : 608
  • ISBN : 9780199775040
  • Language : En, Es, Fr & De
GET BOOK

Charles Fox and Jason Wolf have brought together leading researchers to produce a cutting-edge primer introducing readers to the major concepts in modern evolutionary genetics. This book spans the continuum of scale, from studies of DNA sequence evolution through proteins and development to multivariate phenotypic evolution, and the continuum of time, from ancient events that lead to current species diversity to the rapid evolution seen over relatively short time scales in experimental evolution studies. Chapters are accessible to an audience lacking extensive background in evolutionaryy genetics but also current and in-depth enough to be of value to established researchers in evolution biology.

Handbook of physiology : a critical, comprehensive presentation of physiological knowledge and concepts. Section 11. Aging

Handbook of physiology : a critical, comprehensive presentation of physiological knowledge and concepts. Section 11. Aging
A Book

by Edward J. Masoro

  • Publisher : Unknown Publisher
  • Release : 1995
  • Pages : 681
  • ISBN : 9780195077223
  • Language : En, Es, Fr & De
GET BOOK

Discusses organ system & organismic aging/metabolic & molecular aspects of aging/putative interventions/exercise.

Biology of Aging

Biology of Aging
Observations and Principles

by Robert Arking

  • Publisher : Oxford University Press
  • Release : 2006-02-02
  • Pages : 624
  • ISBN : 9780199727629
  • Language : En, Es, Fr & De
GET BOOK

Robert Arking's Biology of Aging, 3rd edition, is an introductory text to the biology of aging which gives advanced undergraduate and graduate students a thorough review of the entire field. His prior two editions have also served admirably as a reference text for clinicians and scientists. This new edition captures the extraordinary recent advances in our knowledge of the ultimate and proximal mechanisms underlying the phenomenon of aging. As a result, six important conceptual changes are included here: ? Clarified distinctions between the biological mechanisms involved in longevity determination and those involved in senescent processes. ? A new conceptual framework around which we can organize all the new facts about aging. This will assist readers to make sense of the information and use the data to form their own ideas. ? Increased knowledge of aging cells has lead to new ideas on how a cell transits from a healthy state to a senescent state, while still allowing for high levels of intra- and inter-specific variability. ? Discussion of senescent mechanisms assists the reader to understand that aging is a non-programmatic loss of function, likely arising from the loss of regulatory signals, and so is modifiable in the laboratory. ? Because the standard evolutionary story does not fully explain the evolution of social organisms, this edition also includes recent work dealing with intergenerational resource transfers. ? Lastly, if aging mechanisms are plastic, then the demand to move these anti-aging interventions into the human arena will inevitably grow. A discussion of the biological and ethical arguments on both sides of the question frames the question in an appropriate manner. The mass of data related to aging is summarized into fifteen focused chapters, each dealing with some particular aspect of the problem. The last two chapters integrate all this material into a coherent view of how the relevant biological processes change over the life span. This view is expressed in two non-technical figures (you might say that the whole book exists to fully support Figs 9-4 & 14-9), whose meanings are elucidated as the reader progresses through the book.

Does Aging Stop?

Does Aging Stop?
A Book

by Laurence D. Mueller,Casandra L. Rauser,Michael R. Rose

  • Publisher : Oxford University Press
  • Release : 2011-07-29
  • Pages : 224
  • ISBN : 0190454105
  • Language : En, Es, Fr & De
GET BOOK

Does Aging Stop? reveals the most paradoxical finding of recent aging research: the cessation of demographic aging. The authors show that aging stops at the level of the individual organism, and explain why evolution allows this. The implications of this counter-intuitive conclusion are profound, and aging research now needs to accept three uncomfortable truths. First, aging is not a cumulative physiological process. Second, the fundamental theory that is required to explain, manipulate, and probe the phenomena of aging comes from evolutionary biology. Third, strong-inference experimental strategies for aging must be founded in evolutionary research, not cell or molecular biology. The result of fifteen years of research bringing together new applications of evolutionary theory, new models for demography, and massive experimentation, Does Aging Stop? advances an entirely new foundation for the scientific study of aging.

Mechanisms of Life History Evolution

Mechanisms of Life History Evolution
The Genetics and Physiology of Life History Traits and Trade-Offs

by Thomas Flatt,Andreas Heyland

  • Publisher : OUP Oxford
  • Release : 2011-05-12
  • Pages : 506
  • ISBN : 0191621021
  • Language : En, Es, Fr & De
GET BOOK

Life history theory seeks to explain the evolution of the major features of life cycles by analyzing the ecological factors that shape age-specific schedules of growth, reproduction, and survival and by investigating the trade-offs that constrain the evolution of these traits. Although life history theory has made enormous progress in explaining the diversity of life history strategies among species, it traditionally ignores the underlying proximate mechanisms. This novel book argues that many fundamental problems in life history evolution, including the nature of trade-offs, can only be fully resolved if we begin to integrate information on developmental, physiological, and genetic mechanisms into the classical life history framework. Each chapter is written by an established or up-and-coming leader in their respective field; they not only represent the state of the art but also offer fresh perspectives for future research. The text is divided into 7 sections that cover basic concepts (Part 1), the mechanisms that affect different parts of the life cycle (growth, development, and maturation; reproduction; and aging and somatic maintenance) (Parts 2-4), life history plasticity (Part 5), life history integration and trade-offs (Part 6), and concludes with a synthesis chapter written by a prominent leader in the field and an editorial postscript (Part 7).

The University of Virginia Record

The University of Virginia Record
A Book

by University of Virginia

  • Publisher : Unknown Publisher
  • Release : 2003
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
GET BOOK

Aging

Aging
Exploring a Complex Phenomenon

by Shamim I. Ahmad

  • Publisher : CRC Press
  • Release : 2017-10-30
  • Pages : 658
  • ISBN : 1315283883
  • Language : En, Es, Fr & De
GET BOOK

This book is a detailed and comprehensive synthesis of the scientific study of aging. Dozens of contributions from leading scholars review various theories of aging, and molecular, cellular, biochemical and microbial aspects of aging, among just a few of the topics included. Authoritative, wide ranging and thorough, this book will act as a source for experimental design, a comprehensive description of age related diseases, and provide information of the latest molecular theories underlying their causes. Additionally, it will target industries involved in developing anti-aging drugs, post-graduate medical students, and university libraries.

The Aging Mind

The Aging Mind
Opportunities in Cognitive Research

by National Research Council,Division of Behavioral and Social Sciences and Education,Board on Behavioral, Cognitive, and Sensory Sciences,Committee on Future Directions for Cognitive Research on Aging

  • Publisher : National Academies Press
  • Release : 2000-04-18
  • Pages : 288
  • ISBN : 9780309172196
  • Language : En, Es, Fr & De
GET BOOK

Possible new breakthroughs in understanding the aging mind that can be used to benefit older people are now emerging from research. This volume identifies the key scientific advances and the opportunities they bring. For example, science has learned that among older adults who do not suffer from Alzheimer’s disease or other dementias, cognitive decline may depend less on loss of brain cells than on changes in the health of neurons and neural networks. Research on the processes that maintain neural health shows promise of revealing new ways to promote cognitive functioning in older people. Research is also showing how cognitive functioning depends on the conjunction of biology and culture. The ways older people adapt to changes in their nervous systems, and perhaps the changes themselves, are shaped by past life experiences, present living situations, changing motives, cultural expectations, and emerging technology, as well as by their physical health status and sensory-motor capabilities. Improved understanding of how physical and contextual factors interact can help explain why some cognitive functions are impaired in aging while others are spared and why cognitive capability is impaired in some older adults and spared in others. On the basis of these exciting findings, the report makes specific recommends that the U.S. government support three major new initiatives as the next steps for research.

Handbook of the Biology of Aging

Handbook of the Biology of Aging
A Book

by Edward J. Masoro,Steven N. Austad

  • Publisher : Elsevier
  • Release : 2011-04-28
  • Pages : 680
  • ISBN : 0080491405
  • Language : En, Es, Fr & De
GET BOOK

The Handbook of the Biology of Aging, Sixth Edition, provides a comprehensive overview of the latest research findings in the biology of aging. Intended as a summary for researchers, it is also adopted as a high level textbook for graduate and upper level undergraduate courses. The Sixth Edition is 20% larger than the Fifth Edition, with 21 chapters summarizing the latest findings in research on the biology of aging. The content of the work is virtually 100% new. Though a selected few topics are similar to the Fifth Edition, these chapters are authored by new contributors with new information. The majority of the chapters are completely new in both content and authorship. The Sixth Edition places greater emphasis and coverage on competing and complementary theories of aging, broadening the discussion of conceptual issues. Greater coverage of techniques used to study biological issues of aging include computer modeling, gene profiling, and demographic analyses. Coverage of research on Drosophilia is expanded from one chapter to four. New chapters on mammalian models discuss aging in relation to skeletal muscles, body fat and carbohydrate metabolism, growth hormone, and the human female reproductive system. Additional new chapters summarize exciting research on stem cells and cancer, dietary restriction, and whether age related diseases are an integral part of aging. The Handbook of the Biology of Aging, Sixth Edition is part of the Handbooks on Aging series, including Handbook of the Psychology of Aging and Handbook of Aging and the Social Sciences, also in their 6th editions.

Evolution in Changing Environments

Evolution in Changing Environments
Some Theoretical Explorations. (MPB-2)

by Richard Levins

  • Publisher : Princeton University Press
  • Release : 2020-03-31
  • Pages : 132
  • ISBN : 0691209413
  • Language : En, Es, Fr & De
GET BOOK

Professor Levins, one of the leading explorers in the field of integrated population biology, considers the mutual interpenetration and joint evolution of organism and environment, occurring on several levels at once. Physiological and behavioral adaptations to short-term fluctuations of the environment condition the responses of populations to long-term changes and geographic gradients. These in turn affect the way species divide the environments among themselves in communities, and, therefore, the numbers of species which can coexist. Environment is treated here abstractly as pattern: patchiness, variability, range, etc. Populations are studied in their patterns: local heterogeneity, geographic variability, faunistic diversity, etc.

Technology for Adaptive Aging

Technology for Adaptive Aging
A Book

by National Research Council,Division of Behavioral and Social Sciences and Education,Board on Behavioral, Cognitive, and Sensory Sciences,Steering Committee for the Workshop on Technology for Adaptive Aging

  • Publisher : National Academies Press
  • Release : 2004-04-25
  • Pages : 320
  • ISBN : 0309091160
  • Language : En, Es, Fr & De
GET BOOK

Emerging and currently available technologies offer great promise for helping older adults, even those without serious disabilities, to live healthy, comfortable, and productive lives. What technologies offer the most potential benefit? What challenges must be overcome, what problems must be solved, for this promise to be fulfilled? How can federal agencies like the National Institute on Aging best use their resources to support the translation from laboratory findings to useful, marketable products and services? Technology for Adaptive Aging is the product of a workshop that brought together distinguished experts in aging research and in technology to discuss applications of technology to communication, education and learning, employment, health, living environments, and transportation for older adults. It includes all of the workshop papers and the report of the committee that organized the workshop. The committee report synthesizes and evaluates the points made in the workshop papers and recommends priorities for federal support of translational research in technology for older adults.

Contemporary Perspectives on Ageism

Contemporary Perspectives on Ageism
A Book

by Liat Ayalon,Clemens Tesch-Römer

  • Publisher : Springer
  • Release : 2018-05-22
  • Pages : 564
  • ISBN : 3319738208
  • Language : En, Es, Fr & De
GET BOOK

This open access book provides a comprehensive perspective on the concept of ageism, its origins, the manifestation and consequences of ageism, as well as ways to respond to and research ageism. The book represents a collaborative effort of researchers from over 20 countries and a variety of disciplines, including, psychology, sociology, gerontology, geriatrics, pharmacology, law, geography, design, engineering, policy and media studies. The contributors have collaborated to produce a truly stimulating and educating book on ageism which brings a clear overview of the state of the art in the field. The book serves as a catalyst to generate research, policy and public interest in the field of ageism and to reconstruct the image of old age and will be of interest to researchers and students in gerontology and geriatrics.

Omega-3 Fatty Acids in Brain and Neurological Health

Omega-3 Fatty Acids in Brain and Neurological Health
A Book

by Ronald Ross Watson,Fabien De Meester

  • Publisher : Elsevier
  • Release : 2014-06-25
  • Pages : 496
  • ISBN : 0124105475
  • Language : En, Es, Fr & De
GET BOOK

Research has clearly established a link between omega-3 fatty acids and general health, particularly cardiovascular health. Omega-3 Fatty Acids in Brain and Neurological Health is the first book to focus exclusively on the role of omega-3 fatty acids on general brain health. The articles in this collection illustrate omega-3 fatty acids' importance in longevity, cognitive impairment, and structure and function of the brain's neurons. Research has established links between omega-3 fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis. This book encompasses some of the most recent research, including the role of omega-3 fatty acid supplements on hippocampal neurogenesis, substantia nigra modulation, migraine headaches, the developing brain in animals, sleep, and neurodegenerative diseases. This collection helps to push research forward toward a complete understanding of omega-3 fatty acids' relationship to brain and neurological health. The first book-length collection of original research on the connection between omega-3 fatty acids and the brain Provides a comprehensive introduction to the state of research on omega-3 fatty acids and the brain and directions for future research A foundational collection for neuroscience, neurology, and nutrition research

Preparing for an Aging World

Preparing for an Aging World
The Case for Cross-National Research

by National Research Council,Division of Behavioral and Social Sciences and Education,Commission on Behavioral and Social Sciences and Education,Committee on National Statistics,Committee on Population,Panel on a Research Agenda and New Data for an Aging World

  • Publisher : National Academies Press
  • Release : 2001-06-26
  • Pages : 328
  • ISBN : 9780309170871
  • Language : En, Es, Fr & De
GET BOOK

Aging is a process that encompasses virtually all aspects of life. Because the speed of population aging is accelerating, and because the data needed to study the aging process are complex and expensive to obtain, it is imperative that countries coordinate their research efforts to reap the most benefits from this important information. Preparing for an Aging World looks at the behavioral and socioeconomic aspects of aging, and focuses on work, retirement, and pensions; wealth and savings behavior; health and disability; intergenerational transfers; and concepts of well-being. It makes recommendations for a collection of new, cross-national data on aging populationsâ€"data that will allow nations to develop policies and programs for addressing the major shifts in population age structure now occurring. These efforts, if made internationally, would advance our understanding of the aging process around the world.

Teaching About Evolution and the Nature of Science

Teaching About Evolution and the Nature of Science
A Book

by National Academy of Sciences,Division of Behavioral and Social Sciences and Education,Board on Science Education,Working Group on Teaching Evolution

  • Publisher : National Academies Press
  • Release : 1998-04-06
  • Pages : 150
  • ISBN : 9780309185417
  • Language : En, Es, Fr & De
GET BOOK

Today many school students are shielded from one of the most important concepts in modern science: evolution. In engaging and conversational style, Teaching About Evolution and the Nature of Science provides a well-structured framework for understanding and teaching evolution. Written for teachers, parents, and community officials as well as scientists and educators, this book describes how evolution reveals both the great diversity and similarity among the Earth's organisms; it explores how scientists approach the question of evolution; and it illustrates the nature of science as a way of knowing about the natural world. In addition, the book provides answers to frequently asked questions to help readers understand many of the issues and misconceptions about evolution. The book includes sample activities for teaching about evolution and the nature of science. For example, the book includes activities that investigate fossil footprints and population growth that teachers of science can use to introduce principles of evolution. Background information, materials, and step-by-step presentations are provided for each activity. In addition, this volume: Presents the evidence for evolution, including how evolution can be observed today. Explains the nature of science through a variety of examples. Describes how science differs from other human endeavors and why evolution is one of the best avenues for helping students understand this distinction. Answers frequently asked questions about evolution. Teaching About Evolution and the Nature of Science builds on the 1996 National Science Education Standards released by the National Research Council--and offers detailed guidance on how to evaluate and choose instructional materials that support the standards. Comprehensive and practical, this book brings one of today's educational challenges into focus in a balanced and reasoned discussion. It will be of special interest to teachers of science, school administrators, and interested members of the community.