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Critical Care Neurology Part I

Critical Care Neurology Part I
Neurocritical Care

by Andreas H. Kramer

  • Publisher : Elsevier
  • Release : 2017-02-15
  • Pages : 488
  • ISBN : 9780444636003
  • Language : En, Es, Fr & De
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Critical Care Neurology, Part I: Neurocritical Care focuses on the care specialists and general neurologists that consult in the ICU and their work with patients in acute, life-threatening situations who are dealing with neurologic or neurosurgical crises emanating from either a preexisting neurologic syndrome or from a new neurologic complication appearing as a result of another medical or surgical critical illness. These two separate clinical situations form the pillars of neurocritical care, hence these practices are addressed via two separate, but closely related, HCN volumes. Chapters in both focus on pathophysiology and management, and are tailored for both general neurologists and active neurocritical specialists, with a specific focus on management over diagnostics. Part I addresses the principles of neurocritical care and the management of various neurologic diseases. Part II addresses the interplay between neurologic complications and the surgical, medical, cardiac, and trauma of critical illnesses that most typically present in the ICU. Provides an essential neurocritical care overview for general neurologists Presents neurocritical care specialists with an update on severe neurological illness management Offers coverage of all the most frequent neurologic diseases requiring intensive care Includes chapters authored by global leaders in the field, providing the broadest, most expert coverage available on the topics discussed

Critical Care Neurology Part II

Critical Care Neurology Part II
Neurology of Critical Illness

by Anonim

  • Publisher : Elsevier
  • Release : 2017-01-25
  • Pages : 392
  • ISBN : 0128035625
  • Language : En, Es, Fr & De
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Critical Care Neurology, Part II: Neurology of Critical Illness focuses on the care specialists and general neurologists that consult in the ICU and their work with patients in acute, life-threatening situations who are dealing with neurologic or neurosurgical crises emanating from either a preexisting neurologic syndrome or from a new neurologic complication appearing as a result of another medical or surgical critical illness. These two separate clinical situations form the pillars of neurocritical care, hence these practices are addressed via two separate, but closely related, HCN volumes. Chapters in both focus on pathophysiology and management, and are tailored for both general neurologists and active neurocritical specialists, with a specific focus on management over diagnostics. Part I addresses the principles of neurocritical care and the management of various neurologic diseases. Part II addresses the interplay between neurologic complications and the surgical, medical, cardiac, and trauma of critical illnesses that most typically present in the ICU. Provides an essential neurocritical care overview for general neurologists Presents neurocritical care specialists with an update on severe neurological illness management Offers coverage of all the most frequent neurologic diseases requiring intensive care Includes chapters authored by global leaders in the field, providing the broadest, most expert coverage available on the topics discussed

Critical Care Neurology Part I

Critical Care Neurology Part I
Neurocritical Care

by Anonim

  • Publisher : Elsevier
  • Release : 2017-01-25
  • Pages : 488
  • ISBN : 0128035633
  • Language : En, Es, Fr & De
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Critical Care Neurology, Part I: Neurocritical Care focuses on the care specialists and general neurologists that consult in the ICU and their work with patients in acute, life-threatening situations who are dealing with neurologic or neurosurgical crises emanating from either a preexisting neurologic syndrome or from a new neurologic complication appearing as a result of another medical or surgical critical illness. These two separate clinical situations form the pillars of neurocritical care, hence these practices are addressed via two separate, but closely related, HCN volumes. Chapters in both focus on pathophysiology and management, and are tailored for both general neurologists and active neurocritical specialists, with a specific focus on management over diagnostics. Part I addresses the principles of neurocritical care and the management of various neurologic diseases. Part II addresses the interplay between neurologic complications and the surgical, medical, cardiac, and trauma of critical illnesses that most typically present in the ICU. Provides an essential neurocritical care overview for general neurologists Presents neurocritical care specialists with an update on severe neurological illness management Offers coverage of all the most frequent neurologic diseases requiring intensive care Includes chapters authored by global leaders in the field, providing the broadest, most expert coverage available on the topics discussed

Thermoregulation Part II

Thermoregulation Part II
From Basic Neuroscience to Clinical Neurology

by Anonim

  • Publisher : Elsevier
  • Release : 2018-11-17
  • Pages : 456
  • ISBN : 0444640754
  • Language : En, Es, Fr & De
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Thermoregulation, Part II: From Basic Neuroscience to Clinical Neurology, Volume 155, not only reviews how body temperature regulation changes in neurological diseases, but also how this aspect affects the course and outcomes of each disease. Other sections of the volume review three therapeutic approaches that are aimed at manipulating body temperature, including induced hypothermia, induced hyperthermia and antipyretic therapy. The book is comprised of nine sections across two volumes, five dealing with the basic aspects of body temperature regulation and four dealing with the clinical aspects. Basic sections cover the Thermoregulation system, Thermoreceptors, Thermoeffectors, Neural pathways, and Thermoregulation as a homeostatic function. In addition, the book covers the physiology and neuroanatomy of the thermoregulation system and provides descriptions of how the regulation of body temperature intervenes with other physiological functions (such as sleep, osmoregulation, and immunity), stress, exercise and aging. Basic sections serve as an introduction to the four clinical sections: Body Temperature, Clinical Significance, Abnormal Body Temperature, Thermoregulation in Neurological Disease and Therapeutic Interventions. Presents a clear, logical pathway from the fundamental physiology of thermoregulation, through neurobiology, to clinical applications and disease Enables researchers and clinicians to better understand the value of temperature measurement in disease and the use of temperature as a therapy Integrates content from a broad field of research, including topics on the molecular physiology of temperature receptors, to the management of accidental hypothermia

Neurogenetics

Neurogenetics
A Book

by Anonim

  • Publisher : Elsevier
  • Release : 2018-01-09
  • Pages : 480
  • ISBN : 0444640770
  • Language : En, Es, Fr & De
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Neurogenetics, Part II, Volume 148, the latest release in the Handbook of Clinical Neurology, provides the latest information on the genetic methodologies that are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is expected to dramatically grow in scope. Part II builds on the foundation of Part I, expanding the coverage to dementias, paroxysmal disorders, neuromuscular disorders, white matter and demyelination diseases, cerebrovascular diseases, adult psychiatric disorders and cancer and phacomatoses. Contains comprehensive coverage of neurogenetics Details the latest science and its impact on our understanding of neurological, psychiatric disorders Presents a focused reference for clinical practitioners and the neuroscience/neurogenetics research community

Geriatric Neurology

Geriatric Neurology
A Book

by Anonim

  • Publisher : Elsevier
  • Release : 2019-12-18
  • Pages : 616
  • ISBN : 0128051418
  • Language : En, Es, Fr & De
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Geriatric Neurology, Volume 167, serves as an update on the basic biological and behavioral mechanisms underlying the aging process, with an emphasis on neurological aging and state-of-the-art reviews on our understanding of vascular, cognitive, neurodegenerative and neuropsychiatric diseases in the elderly. Developed with an eye to providing both the basic underpinnings of age-related changes and the clinical information necessary to aid in diagnostics and treatment, the book serves as a useful volume for students, basic and translational scientists, and practicing clinicians on how to understand and treat common neurological disorders in the elderly. Reviews the foundations of geriatric neurology, including the fundamentals of age associated changes in molecular biology, altered pharmacokinetics and psychopharmacology that make drug therapy in the elderly different from younger patients Contains major advances in our understanding of neurodegenerative diseases Features contributions from world leaders in geriatric neurology–the broadest, most expert coverage available

Neurology of Vision and Visual Disorders

Neurology of Vision and Visual Disorders
A Book

by Anonim

  • Publisher : Elsevier
  • Release : 2021-04-06
  • Pages : 410
  • ISBN : 0128213787
  • Language : En, Es, Fr & De
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Neurology of Vision and Visual Disorders, Volume 178 in the Handbooks of Neurology series provides comprehensive summaries of recent research on the brain and nervous system. This volume reviews alterations in vision that stem from the retina to the cortex. Coverage includes content on vision and driving derived from the large amount of time devoted in clinics to determining who is safe to drive, along with research on the interplay between visual loss, attention and strategic compensations that may determine driving suitability. The title concludes with vision therapies and the evidence behind these approaches. Each chapter is co-written by a basic scientist collaborating with a clinician to provide a solid underpinning of the mechanisms behind the clinical syndromes. Reviews the neurological underpinnings of visual perception disorders Encompasses the cortex to the retina Covers functional organization, electrophysiology and subcortical visual pathways Discusses assessment, diagnosis and management of visual perception disorders Includes international experts from Australia, Canada, Denmark, Germany, Singapore, and the UK and US

Heart and Neurologic Disease

Heart and Neurologic Disease
A Book

by Anonim

  • Publisher : Elsevier
  • Release : 2021-02-23
  • Pages : 440
  • ISBN : 0128203897
  • Language : En, Es, Fr & De
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The Handbook of Clinical Neurology series volumes provide comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. Cardiac disorders and diseases may often co-occur with, or cause, subsequent neurological disorders. Heart and Neurologic Disease identifies the top cardiac diseases and disorders most likely to have neurological disorders, how they will present, and how they are best treated. It identifies the mechanisms of action explaining why the conditions co-occur, and what clinicians should look for symptom wise, and how risk may be assessed. Coverage includes genetic cardiac disorders, cardiac trauma, surgery, infection, disease, and arrhythmia. Identifies the top cardiac diseases and disorders most likely to have neurological complications Specifies how the neurological complication will present and advance and how it should be treated Discusses the mechanism of action—why the two conditions co-occur Includes genetic conditions, trauma, surgery, infection, disease, arrythmias, and more Covers prevention and risk assessment

Psychopharmacology of Neurologic Disease

Psychopharmacology of Neurologic Disease
Handbook of Clinical Neurology Series

by Anonim

  • Publisher : Elsevier
  • Release : 2019-11-12
  • Pages : 458
  • ISBN : 0444640134
  • Language : En, Es, Fr & De
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Psychopharmacology of Neurologic Disease, Volume 165 in the Handbook of Clinical Neurology series, provides clinicians with an up-to-date, critical review of the best approaches to treatment of neurologic disease as discussed by experienced clinical investigators. The book is organized into sections on dementia, delirium, movement disorders, hereditary degenerative disease, epilepsy and psychogenic seizures, brain vascular disease, pseudobulbar affect, traumatic brain injury, neuro-oncology, multiple sclerosis and other demyelinating disorders, chronic fatigue syndrome/fibromyalgia, pain, headache, sleep disorders, autoimmune encephalitis/anti- NMDA encephalitis, functional sensory neurologic symptom disorders and neurodevelopmental disorders. Each of these diagnostic categories has a significant incidence of behavioral symptomatology that is secondary to the neurologic diagnosis that can serve to complicate other therapeutic interventions, alter the course of illness, and cause distress in patients and family caregivers. Provides a systematic, evidence-based compendium of best practices in the treatment of behavioral symptomatology relating to neurologic conditions Integrates state-of-the-art approaches in treating all behavioral symptomatology across all major neurologic disorders Explores psychopharmacological intervention, non-pharmacological strategies, behavioral symptomatology, and therapeutic interventions

Disorders of Emotion in Neurologic Disease

Disorders of Emotion in Neurologic Disease
A Book

by Anonim

  • Publisher : Elsevier
  • Release : 2021-08-11
  • Pages : 338
  • ISBN : 0128222891
  • Language : En, Es, Fr & De
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Disorders of Emotion in Neurologic Disease, Volume 183 in the Handbook of Clinical Neurology Series, informs clinicians on which neurologic diseases are likely to have a secondary effect on emotion, what to look for in diagnosis, and best practices for treatment. The book begins with an understanding of the neurological basis for emotions in order to better understand what goes awry in neurological disease. It then discusses specific neurologic diseases and disorders affecting emotion. Reviews the neurology of emotions Specifies neurologic diseases that affect emotional expression Informs clinicians on how to diagnose, along with best practices for treatment Includes coverage of stroke, dementia, epilepsy, Huntington's, Parkinson's, TBI, and more

The Human Hypothalamus

The Human Hypothalamus
Neuroendocrine Disorders

by Dick F. Swaab,Ruud M. Buijs,Paul J. Lucassen,Ahmad Salehi,Felix Kreier

  • Publisher : Elsevier
  • Release : 2021-07-04
  • Pages : 566
  • ISBN : 0128206845
  • Language : En, Es, Fr & De
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The Human Hypothalamus: Neuroendocrine Disorders, Volume 181 in the Handbook of Clinical Neurology series, provides comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. This volume summarizes the role of the hypothalamus in neuroendocrine disorders, identifying the mechanism of action, disorder etiology, and best practices for assessment and treatment. Disorders covered include pituitary hypothalamic disorders of development and growth, hypothalamic tumor related disorders, hypothalamic autoimmune disorders and infection, disorders of vasopressin, water and sodium homeostasis, eating disorders, and gonadotropic hormone regulation disorders. Discusses the importance of the hypothalamus in human growth and development Reviews hypothalamic related tumors, as well as pituitary, autoimmune, vasopressin and hormone regulation disorders Includes metabolic and eating disorders Identifies mechanisms of disease action and etiology Provides best practice information for assessment and treatment

Neurocognitive Development: Disorders and Disabilities

Neurocognitive Development: Disorders and Disabilities
A Book

by Anonim

  • Publisher : Elsevier
  • Release : 2020-09-25
  • Pages : 426
  • ISBN : 0444641491
  • Language : En, Es, Fr & De
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This is one volume of a two-volume work on neurocognitive development, focusing separately on normative and non-normative development. The disorders and disabilities volume focuses on disorders of intellectual abilities, language, learning memory as well as psychiatric developmental disorders. The developmental aspects of neurological diseases in children is also covered. Chapters discuss when and how these disorders develop, the genetics and neurophysiology of their operation, and their evaluation and assessment in clinical practice. Assessment, treatment, and long-term outcome are provided as well as advances in methods and tools for assessment. This book will serve as a comprehensive reference to researchers in cognitive development in neuroscience, psychology, and medicine, as well as to clinicians and allied health professionals focused on developmental disabilities (child neurologists, pediatric neuropsychologists, child psychiatrists, speech and language therapists, and occupational therapists.) Summarizes research on neurocognitive developmental disorders and disabilities Includes disorders of intellectual abilities, language, learning, memory, and more Separately covers developmental aspects of neurological diseases in children Features advances in methods and tools of assessment Reviews patient care, rehabilitation, and long-term outcomes Provides interdisciplinary information of use to both researchers and clinicians

Neurocognitive Development: Normative Development

Neurocognitive Development: Normative Development
A Book

by Anonim

  • Publisher : Elsevier
  • Release : 2019-09-22
  • Pages : 532
  • ISBN : 0444641513
  • Language : En, Es, Fr & De
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This is one of a two-volume work on neurocognitive development, focusing separately on normative and non-normative development. The normative volume focuses on neurology, biology, genetics, and psychology of normative cognitive development. It covers the development of intellectual abilities, visual perception, motor function, language, memory, attention, executive function, social cognition, learning abilities, and affect and behavior. The book identifies when and how these functions develop, the genetics and neurophysiology of their operation, and their evaluation and assessment in clinical practice. This book will serve as a comprehensive reference to researchers in cognitive development in neuroscience, psychology, and medicine, as well as to clinicians and allied health professionals focused on developmental disabilities (child neurologists, pediatric neuropsychologists, child psychiatrists, speech and language therapists, and occupational therapists.) Summarizes research on normative neurocognitive development Includes intellectual abilities, language, memory, attention, motor function, and more Discusses genetics and environmental influences on development Provides interdisciplinary information of use to both researchers and clinicians

Brain-Computer Interfaces

Brain-Computer Interfaces
A Book

by Anonim

  • Publisher : Elsevier
  • Release : 2020-03-10
  • Pages : 390
  • ISBN : 0444639330
  • Language : En, Es, Fr & De
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Brain-Computer Interfacing, Volume 168, not only gives readers a clear understanding of what BCI science is currently offering, but also describes future expectations for restoring lost brain function in patients. In-depth technological chapters are aimed at those interested in BCI technologies and the nature of brain signals, while more comprehensive summaries are provided in the more applied chapters. Readers will be able to grasp BCI concepts, understand what needs the technologies can meet, and provide an informed opinion on BCI science. Explores how many different causes of disability have similar functional consequences (loss of mobility, communication etc.) Addresses how BCI can be of use Presents a multidisciplinary review of BCI technologies and the opportunities they provide for people in need of a new kind of prosthetic Offers a comprehensive, multidisciplinary review of BCI for researchers in neuroscience and traumatic brain injury that is also ideal for clinicians in neurology and neurosurgery

Clinical Neurophysiology: Basis and Technical Aspects

Clinical Neurophysiology: Basis and Technical Aspects
Handbook of Clinical Neurology Series

by Anonim

  • Publisher : Elsevier
  • Release : 2019-07-03
  • Pages : 622
  • ISBN : 0444640339
  • Language : En, Es, Fr & De
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Clinical Neurophysiology: Basis and Technical Aspects, the latest release in the Handbook of Clinical Neurology series, is organized into sections on basic physiological concepts, on the function and limitations of modern instrumentation, and on other fundamental or methodologic aspects related to the recording of various bioelectric signals from the nervous system for clinical or investigative purposes. There is discussion of the EEG, nerve conduction studies, needle electromyography, intra-operative clinical neurophysiology, sleep physiology and studies, the autonomic nervous system, various sensory evoked potentials, and cognitive neurophysiology. Provides an up-to-date review on the practice of neurophysiological techniques in the assessment of neurological disease Explores the electrophysiological techniques used to better understand neurological function and dysfunction, first in the area of consciousness and epilepsy, then in the areas of the peripheral nervous system and sleep Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, magnetoencephalography, laser evoked potentials, and transcranial magnetic stimulation

The Neurology of HIV Infection

The Neurology of HIV Infection
A Book

by Anonim

  • Publisher : Elsevier
  • Release : 2018-03-29
  • Pages : 320
  • ISBN : 0444638504
  • Language : En, Es, Fr & De
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The Neurology of HIV Infection covers all aspects of nervous system involvement and pathology in HIV-infected individuals. Specialists in this field cover epidemiology, global aspects, pathology and pathogenesis of nervous system disease in HIV-infection. All complications, including the pathology caused by HIV itself and all opportunistic infections of the nervous system are reviewed in detail. Both central nervous and peripheral nervous system complications, including neuropathies and myopathies, are discussed. Key chapters on global developments, HIV-associated neurocognitive disorders, IRIS, stroke and neuro-aids in children complete this volume. Covers all aspects of nervous system involvement and pathology in HIV-infected individuals Includes the pathology caused by HIV and all opportunistic infections of the nervous system Presents key chapters that focus on global developments, HIV-associated neurocognitive disorders, IRIS, stroke and neuro-aids in children

The Cerebellum: Disorders and Treatment

The Cerebellum: Disorders and Treatment
A Book

by Anonim

  • Publisher : Elsevier
  • Release : 2018-06-08
  • Pages : 440
  • ISBN : 0444641904
  • Language : En, Es, Fr & De
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The Cerebellum: Disorders and Treatment, Volume 155 updates readers on the latest and clinically relevant advances in the study of cerebellar diseases in children and adults. It is organized into sections detailing: (1) Disorders (starting from the fetal cerebellum, to adult cerebellum) encountered during daily practice, and (2) Therapy (including insights into innovative drug and rehabilitative approaches). The book's innovative structure discusses cerebellar disorders in children and adults as a continuum, with its companion volume, The Cerebellum: From Embryology to Diagnostic Investigations detailing embryology, anatomy, function and diagnostic investigations and neuroimaging, including conventional sequences, diffusion tensor imaging, functional MRI, and connectivity studies. Provides an in-depth understanding of the cerebellum and its involvement in a wide variety of diseases Explores long-term outcome data of pediatric cerebellar diseases and potential problems in adult life for patients with pediatric cerebellar diseases Features chapters co-authored by two experts, combining expertise in both pediatric and adult cerebellar diseases

Pediatric Neurology

Pediatric Neurology
A Book

by Olivier Dulac,Maryse Lassonde,Harvey B. Sarnat

  • Publisher : Newnes
  • Release : 2013-04-24
  • Pages : 892
  • ISBN : 0444626980
  • Language : En, Es, Fr & De
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The child is neither an adult miniature nor an immature human being: at each age, it expresses specific abilities that optimize adaptation to its environment and development of new acquisitions. Diseases in children cover all specialties encountered in adulthood, and neurology involves a particularly large area, ranging from the brain to the striated muscle, the generation and functioning of which require half the genes of the whole genome and a majority of mitochondrial ones. Human being nervous system is sensitive to prenatal aggression, is particularly immature at birth and development may be affected by a whole range of age-dependent disorders distinct from those that occur in adults. Even diseases more often encountered in adulthood than childhood may have specific expression in the developing nervous system. The course of chronic neurological diseases beginning before adolescence remains distinct from that of adult pathology – not only from the cognitive but also motor perspective, right into adulthood, and a whole area is developing for adult neurologists to care for these children with persisting neurological diseases when they become adults. Just as pediatric neurology evolved as an identified specialty as the volume and complexity of data became too much for the general pediatician or the adult neurologist to master, the discipline has now continued to evolve into so many subspecialties, such as epilepsy, neuromuscular disease, stroke, malformations, neonatal neurology, metabolic diseases, etc., that the general pediatric neurologist no longer can reasonably possess in-depth expertise in all areas, particularly in dealing with complex cases. Subspecialty expertise thus is provided to some trainees through fellowship programmes following a general pediatric neurology residency and many of these fellowships include training in research. Since the infectious context, the genetic background and medical practice vary throughout the world, this diversity needs to be represented in a pediatric neurology textbook. Taken together, and although brain malformations (H. Sarnat & P. Curatolo, 2007) and oncology (W. Grisold & R. Soffietti) are covered in detail in other volumes of the same series and therefore only briefly addressed here, these considerations justify the number of volumes, and the number of authors who contributed from all over the world. Experts in the different subspecialties also contributed to design the general framework and contents of the book. Special emphasis is given to the developmental aspect, and normal development is reminded whenever needed – brain, muscle and the immune system. The course of chronic diseases into adulthood and ethical issues specific to the developing nervous system are also addressed. A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology International list of contributors including the leading workers in the field Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care

The Practice of Emergency and Critical Care Neurology

The Practice of Emergency and Critical Care Neurology
A Book

by Eelco F.M. Wijdicks

  • Publisher : Oxford University Press
  • Release : 2016-04-11
  • Pages : 864
  • ISBN : 0190259566
  • Language : En, Es, Fr & De
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Fully updated and revised, the second edition of The Practice of Emergency and Critical Care Neurology puts a more modern approach on the practice of emergency neurological care. When most texts within the field focus on the theoretical aspects, this book concentrates on the management of neurologic conditions, recognition of deterioration of neurologic functions, neurosurgical procedures, and immediate interventions. This text also presents hard data to explain why we do what we do. Dr. Wijdicks condenses essential information into several sections comprising of the principles in recognizing critically ill neurologic patients in the emergency department, the evaluation of symptoms indicating critical emergency, general principles of managing critically ill patients, monitoring devices and diagnostic tests, complete management of specific disorders in the neurosciences intensive care unit, postoperative neurosurgical and neurointerventional complications, management of medical complications, and end of life care. Key Features of the New Edition include 1. Additional chapters on critical consults in surgical and medical ICUs, critical care management, and comprehensive monitoring and biomarkers to reflect new research; 2. Rich illustrations using color photos of patients and drawings of important basic concepts of mechanism of acute neurologic disease; 3. Fully updated and comprehensive reference list; 4. A pocket book of selected tables and figures covering all essential points for quick reference and as a survival guide for house staff. This is the go-to guide for every physician, staff neurologist, neurointensivist, resident, and fellow in training with managing acutely ill neurologic patients.

Cerebrospinal Fluid in Neurologic Disorders

Cerebrospinal Fluid in Neurologic Disorders
A Book

by Anonim

  • Publisher : Elsevier
  • Release : 2017-11-17
  • Pages : 320
  • ISBN : 0128043245
  • Language : En, Es, Fr & De
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Cerebrospinal Fluid in Neurologic Disorders, Volume 146 provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker. The second part addresses the main purpose of the volume, describing CSF from a research perspective in context with the most important diagnostic entities in neurology. The book's authors provide insight into the current understanding of CSF changes in these various conditions and what it tells us about the nature of neurological diseases. Furthermore, methodological aspects are discussed, as are shortcomings that need to be addressed. Finally, the book provides an outlook for potential directions that can be explored to improve the various aspects of CSF research with the ultimate goal of being incorporated in clinical practice. Provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker Addresses relevant research in context with the most important diagnostic entities in neurology Edited by leading authors in CSF research from around the globe, presenting the broadest, most expert coverage available