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Detection and Identification of Designer Drugs

Detection and Identification of Designer Drugs
A Book

by Brian F Thomas

  • Publisher : Elsevier
  • Release : 2017-11-01
  • Pages : 150
  • ISBN : 0128118156
  • Language : En, Es, Fr & De
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Detection and Identification of Designer Drugs, a title in the Emerging Issues in Analytical Chemistry series, presents both an overview and a guide to techniques for anyone studying or engaging in designer drug analysis. Proliferation of the synthesis and use of designer drugs is a serious public health problem with social, economic and legal implications. Whether abuse is studied at the population level or the individual level, researchers need both background and highly detailed technical information on specific drugs and drug classes in order to combat the proliferation and highly damaging consequences of these substances. Author Brian F. Thomas provides a comprehensive discussion that emphasizes the potential threat to society, presents the ongoing challenges confronting the various laboratory approaches to detection and identification of new chemical entities and informs the development of improved analytical solutions for use in legislation, law enforcement and treatment. Summarizes the literature and evaluates the strengths and weaknesses of analytical methods for detecting and identifying designer drugs Offers authoritative information from author Brian F. Thomas, an expert with over 30 years of experience in the field Directs the reader to sources of further reading at the conclusion of each chapter Emphasizes the potential threat to society and presents ongoing challenges confronting various laboratory approaches to detection and identification of new chemical entities

Detection of Drug Misuse

Detection of Drug Misuse
Biomarkers, Analytical Advances and Interpretation

by Kim Wolff

  • Publisher : Royal Society of Chemistry
  • Release : 2017-04-13
  • Pages : 396
  • ISBN : 1782621571
  • Language : En, Es, Fr & De
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This book describes recent advances in biomarkers, instrumentation and analysis methodology for identifying drug misuse. It is aimed at healthcare professionals, academics and postgraduates.

Chromatographic Techniques in the Forensic Analysis of Designer Drugs

Chromatographic Techniques in the Forensic Analysis of Designer Drugs
A Book

by Teresa Kowalska,Mieczyslaw Sajewicz,Joseph Sherma

  • Publisher : CRC Press
  • Release : 2018-01-31
  • Pages : 478
  • ISBN : 1315313162
  • Language : En, Es, Fr & De
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There is a dramatic rise of novel drug use due to the increased popularity of so-called designer drugs. These synthetic drugs can be illegal in some countries, but legal in others and novel compounds unknown to drug chemistry emerge monthly. This thoughtfully constructed edited reference presents the main chromatographic methodologies and strategies used to discover and analyze novel designer drugs contained in diverse biological materials. The methods are based on molecular characteristics of the drugs belonging to each individual class of compounds, so it will be clear how the current methods are adaptable to future new drugs that appear in the market.

Chromatographic Techniques in the Forensic Analysis of Designer Drugs

Chromatographic Techniques in the Forensic Analysis of Designer Drugs
A Book

by Teresa Kowalska,Mieczyslaw Sajewicz,Joseph Sherma

  • Publisher : CRC Press
  • Release : 2018-01-31
  • Pages : 478
  • ISBN : 1315313154
  • Language : En, Es, Fr & De
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There is a dramatic rise of novel drug use due to the increased popularity of so-called designer drugs. These synthetic drugs can be illegal in some countries, but legal in others and novel compounds unknown to drug chemistry emerge monthly. This thoughtfully constructed edited reference presents the main chromatographic methodologies and strategies used to discover and analyze novel designer drugs contained in diverse biological materials. The methods are based on molecular characteristics of the drugs belonging to each individual class of compounds, so it will be clear how the current methods are adaptable to future new drugs that appear in the market.

The Role of Ultra High Performance Liquid Chromatography with Time of Flight Detection for the Identification of Synthetic Cannabinoids in Seized Drugs

The Role of Ultra High Performance Liquid Chromatography with Time of Flight Detection for the Identification of Synthetic Cannabinoids in Seized Drugs
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2015
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Synthetic Cathinones

Synthetic Cathinones
Novel Addictive and Stimulatory Psychoactive Substances

by Jolanta B. Zawilska

  • Publisher : Springer
  • Release : 2018-04-16
  • Pages : 207
  • ISBN : 3319787071
  • Language : En, Es, Fr & De
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Over the last decade, and particularly during the recent five years, a rapidly increasing number of novel psychoactive substance (NPSs), often marketed as “designer drugs”, “legal highs”, “herbal highs”, “research or intermediate chemicals” and “laboratory reagents”, has appeared on the drug market in an effort to bypass controlled substance legislation. NPSs encompass a wide range of different compounds and drug classes but had been dominated by synthetic cannabinomimetics and psychostimulatory synthetic cathinones, so-called β-keto amphetamines. Compounds from the later class were first detected in Europe in 2004, and since then 103 new cathinones have been identified and reported to the European Monitoring Centre for Drugs and Drug Addiction, with 57 during the last two years. Synthetic cathinones – novel addictive and stimulatory psychoactive substances is the first publication of this kind that provides readers with background on chemical structures, detection, prevalence and motivation of use of the very popular group of NPSs. This book also presents comprehensive overview of the mechanisms of action, pharmacological activity, and main metabolic pathways of synthetic cathinones, followed by a detailed discussion of the acute and chronic toxicity associated with the use of these substances. Written by international experts in the field, this multi-authored book is a valuable reference not only for scientists, clinicians and academics, but also for readers representing different professional background who are involved in educational-prophylactic activities directed to harm reduction of psychoactive compounds.

Pharmacology and Abuse of Cocaine, Amphetamines, Ecstasy and Related Designer Drugs

Pharmacology and Abuse of Cocaine, Amphetamines, Ecstasy and Related Designer Drugs
A comprehensive review on their mode of action, treatment of abuse and intoxication

by Enno Freye

  • Publisher : Springer Science & Business Media
  • Release : 2009-09-21
  • Pages : 300
  • ISBN : 9789048124480
  • Language : En, Es, Fr & De
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Finally - a book that covers all aspects of the illicit use of cocaine, amphetamines, ecstasy and/or designer drugs such as GHB, written by two experts in their field. The use of these drugs remains a continuous threat in health and medical care delivery, and this book will be an essential asset to the physician who may have to face the evaluation of patients whose use of these drugs compromises an effective treatment plan for other health issues. The book has been conceived to fill the void in existing physician reference materials, and provides a comprehensive review of the theoretical knowledge and scope of pharmacotherapy in individuals who are hooked on a psychoactive substance. While detailed scientific information is obtainable in other major articles, the book's straightforward format and style, along with its illustrations, will make for easy reading as emphasis is put on information specifically related to drugs that occur most abused in today’s society. The information provided is based on clinical practice rather than pure experimental data, which will give the physician more effective tools useful in their daily practice. Many mechanisms of action of abuse are described in detail and references are provided to direct the reader to further sources for additional information. As a special feature, the book incorporates uncluttered tables and charts, which result in immediate clarification of the mode of action on the central nervous system and the reason for misuse, thus avoiding usual long and fatiguing text in common reference books. The book aims to give the reader a clear and concise plan on what to do when being faced with an overdose situation. A well-organized Table of Contents rapidly leads the reader from general pharmacological issues to the specific overdose syndrome and its management. Additionally, significant emphasis is placed on the practical do's and don’ts for physicians, with special reference to the predictive signs of aberrant drug-related behavior and the identification of the drug diverter by using urine drug screening.

Forensic Toxicology

Forensic Toxicology
A Book

by Max M. Houck

  • Publisher : Academic Press
  • Release : 2018-01-02
  • Pages : 418
  • ISBN : 0128008180
  • Language : En, Es, Fr & De
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Forensic Toxicology, the latest release in the Advanced Forensic Science Series that grew out of recommendations from the 2009 NAS Report, Strengthening Forensic Science: A Path Forward will serve as a graduate level text for those studying and teaching forensic toxicology. It is also an excellent reference for the forensic practitioner’s library or for use in their casework. Coverage includes a wide variety of methods used, along with pharmacology and drugs and professional issues they may encounter. Edited by a world-renowned, leading forensic expert, this updated edition is a long overdue solution for the forensic science community. Provides basic principles of forensic science and an overview of forensic toxicology Contains information on a wide variety of methods Covers pharmacology and drugs, matrices and interpretation Includes a section on professional issues, such as crime scene to court, lab reports, health and safety, post-mortem and drug facilitated crimes Incorporates effective pedagogy, key terms, review questions, discussion questions and additional reading suggestions

Forensic Chemistry

Forensic Chemistry
A Book

by Max M. Houck

  • Publisher : Academic Press
  • Release : 2015-01-26
  • Pages : 492
  • ISBN : 0128006242
  • Language : En, Es, Fr & De
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Forensic Chemistry is the first publication to provide coordinated expert content from world-renowned leading authorities in forensic chemistry. Covering the range of forensic chemistry, this volume in the Advanced Forensic Science Series provides up-to-date scientific learning on drugs, fire debris, explosives, instrumental methods, interpretation, and more. Technical information, written with the degreed professional in mind, brings established methods together with newer approaches to build a comprehensive knowledge base for the student and practitioner alike. Like each volume in the Advanced Forensic Science Series, review and discussion questions allow the text to be used in classrooms, training programs, and numerous other applications. Sections on fundamentals of forensic science, history, safety, and professional issues provide context and consistency in support of the forensic enterprise. Forensic Chemistry sets a new standard for reference and learning texts in modern forensic science. Advanced articles written by international forensic chemistry experts Covers the range of forensic chemistry, including methods and interpretation Includes entries on history, safety, and professional issues Useful as a professional reference, advanced textbook, or training review

Mass Spectral and GC Data of Drugs, Poisons, Pesticides, Pollutants and Their Metabolites, Parts I-III

Mass Spectral and GC Data of Drugs, Poisons, Pesticides, Pollutants and Their Metabolites, Parts I-III
A Book

by Karl Pfleger,Hans H. Maurer,Armin A. Weber

  • Publisher : Wiley-VCH
  • Release : 1992-12-08
  • Pages : 3409
  • ISBN : 9783527269891
  • Language : En, Es, Fr & De
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The new edition of this famous collection: * triples the number of spectra * now includes pesticides and pollutants * also allows identification of doping agents * offers nearly complete coverage of centrally active drugs, designer drugs, registered pesticides, pollutants, organic solvents All the spectra were obtained in the authors' laboratory using GC-MS coupling techniques. As the subtitle (in its new wording) suggests, the collection now reaches far beyond the needs of clinical toxicologists and pharmacologists. Above all, the inclusion of pesticides and pollutants makes this data collection invaluable for environmental chemists, occupational toxicologists and food analysts as well. Unmatched in scope, quality and reliability, this collection is the result of a unique effort. It is indispensable for laboratories in this field all over the world.

Designer Drugs Directory

Designer Drugs Directory
A Book

by K. Valter,P. Arrizabalaga

  • Publisher : Elsevier
  • Release : 1998-10-16
  • Pages : 216
  • ISBN : 9780080530321
  • Language : En, Es, Fr & De
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This book is intended to serve as quick reference handbook on so-called designer drugs. These new, mainly synthetic compounds are also often referred to as analogues of controlled substances. This new work provides a unique directory of 104 designer drugs. This class of drugs is rapidly growing in variety and number of compounds. Although identification, toxicology and other properties have been thoroughly investigated, their analogues and derivatives remain poorly documented. This book fills the gap. Data which is available is often contradictory and confused. This directory provides a critical treatment of the subject which is thoroughly indexed including both the subject index and an index listing more that 230 street names of the described designer drugs. Divided into two parts; the first section describes aspects of designer drug manufacture, new abuse trends, sources of information and terminology. The second, descriptive part, classifies the drugs into ten main categories according to their chemical structure and prevalent pharmacological action. A separate chapter is devoted to each category, followed by a set of corresponding data sheets, street names and eventual synonyms, Toxicological data, short notes on the history of drugs as well as the most pertinent bibliographic references are included.

Encyclopedia of Forensic Sciences

Encyclopedia of Forensic Sciences
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2012-12-28
  • Pages : 2250
  • ISBN : 0123821665
  • Language : En, Es, Fr & De
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Forensic science includes all aspects of investigating a crime, including: chemistry, biology and physics, and also incorporates countless other specialties. Today, the service offered under the guise of "forensic science’ includes specialties from virtually all aspects of modern science, medicine, engineering, mathematics and technology. The Encyclopedia of Forensic Sciences, Second Edition is a reference source that will inform both the crime scene worker and the laboratory worker of each other’s protocols, procedures and limitations. Written by leading scientists in each area, every article is peer reviewed to establish clarity, accuracy, and comprehensiveness. As reflected in the specialties of its Editorial Board, the contents covers the core theories, methods and techniques employed by forensic scientists – and applications of these that are used in forensic analysis. This 4-volume set represents a 30% growth in articles from the first edition, with a particular increase in coverage of DNA and digital forensics Includes an international collection of contributors The second edition features a new 21-member editorial board, half of which are internationally based Includes over 300 articles, approximately 10pp on average Each article features a) suggested readings which point readers to additional sources for more information, b) a list of related Web sites, c) a 5-10 word glossary and definition paragraph, and d) cross-references to related articles in the encyclopedia Available online via SciVerse ScienceDirect. Please visit www.info.sciencedirect.com for more information This new edition continues the reputation of the first edition, which was awarded an Honorable Mention in the prestigious Dartmouth Medal competition for 2001. This award honors the creation of reference works of outstanding quality and significance, and is sponsored by the RUSA Committee of the American Library Association

Designer Drugs, 1985

Designer Drugs, 1985
Hearing Before the Subcommittee on Children, Family, Drugs, and Alcoholism of the Committee on Labor and Human Resources, United States Senate, Ninety-ninth Congress, First Session ... July 25, 1985

by United States. Congress. Senate. Committee on Labor and Human Resources. Subcommittee on Children, Family, Drugs and Alcoholism

  • Publisher : Unknown Publisher
  • Release : 1985
  • Pages : 94
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Essentials of Autopsy Practice

Essentials of Autopsy Practice
Reviews, Updates, and Advances

by Guy N. Rutty

  • Publisher : Springer
  • Release : 2017-02-14
  • Pages : 182
  • ISBN : 3319469975
  • Language : En, Es, Fr & De
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This book covers topical subjects within the field of death investigation, where changes in practice have recently occurred. As the area of dating of wounds has changed since the subject was addressed in a previous volume, this subject is revisited for the first time. The remaining subjects covered in this volume embrace the multi-disciplinary approach required for death investigation, and address advances in the field of forensic radiology imaging, pathology, and toxicology. There is also a chapter on cardiopulmonary resuscitation which explains clinical processes and procedures that may occur to an individual immediately before death that may have a bearing on the subsequent autopsy findings. Essentials of Autopsy Practice: Reviews, Updates and Advances is an educational and practical resource aimed at trainees and consultants, generalists and specialists, and the new multi-disciplinary team alike.

Chemical Abstracts

Chemical Abstracts
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2002
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Current Analytical Trends in Drug Testing in Clinical and Forensic Toxicology

Current Analytical Trends in Drug Testing in Clinical and Forensic Toxicology
A Book

by Eugenia Gallardo,Mário Barroso,Marta Concheiro-Guisan,Ana de-Castro-Ríos

  • Publisher : Frontiers Media SA
  • Release : 2021-06-24
  • Pages : 329
  • ISBN : 2889668940
  • Language : En, Es, Fr & De
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Novel Psychoactive Substances

Novel Psychoactive Substances
Classification, Pharmacology and Toxicology

by Paul Dargan,David Wood

  • Publisher : Academic Press
  • Release : 2013-08-06
  • Pages : 440
  • ISBN : 0124159117
  • Language : En, Es, Fr & De
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Novel Psychoactive Substances: Classification, Pharmacology and Toxicology provides readers with background on the classification, detection, supply and availability of novel psychoactive substances, otherwise known as "legal highs." This book also covers individual classes of novel psychoactive substances that have recently emerged onto the recreational drug scene and provides an overview of the pharmacology of the substance followed by a discussion of the acute and chronic harm or toxicity associated with the substance. Written by international experts in the field, this multi-authored book is a valuable reference for scientists, clinicians, academics, and regulatory and law enforcement professionals. Includes chapters written by international experts in the field. Provides a comprehensive look at the classification, detection, availability and supply of novel psychoactive substances, in addition to the pharmacology and toxicology associated with the substance. Offers a single source for all interested parties working in this area, including scientists, academics, clinicians, law enforcement and regulatory agencies. Provides a full treatment of novel psychoactive substances that have recently emerged onto the recreational drug scene including mephedrone and the synthetic cannabinoid receptors in ‘spice’ / ‘K2’.

Interpretation of MS-MS Mass Spectra of Drugs and Pesticides

Interpretation of MS-MS Mass Spectra of Drugs and Pesticides
A Book

by Wilfried M. A. Niessen,Ricardo A. Correa C.

  • Publisher : John Wiley & Sons
  • Release : 2017-01-03
  • Pages : 416
  • ISBN : 111929424X
  • Language : En, Es, Fr & De
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Provides comprehensive coverage of the interpretation of LC–MS–MS mass spectra of 1300 drugs and pesticides Provides a general discussion on the fragmentation of even-electron ions (protonated and deprotonated molecules) in both positive-ion and negative-ion modes This is the reference book for the interpretation of MS–MS mass spectra of small organic molecules Covers related therapeutic classes of compounds such as drugs for cardiovascular diseases, psychotropic compounds, drugs of abuse and designer drugs, antimicrobials, among many others Covers general fragmentation rule as well as specific fragmentation pathways for many chemical functional groups Gives an introduction to MS technology, mass spectral terminology, information contained in mass spectra, and to the identification strategies used for different types of unknowns

Toxicology Testing, An Issue of Clinics in Laboratory Medicine - E-Book

Toxicology Testing, An Issue of Clinics in Laboratory Medicine - E-Book
A Book

by Michael G. Bissell

  • Publisher : Elsevier Health Sciences
  • Release : 2012-09-24
  • Pages : 240
  • ISBN : 1455747874
  • Language : En, Es, Fr & De
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This issue of Clinics in Laboratory Medicine, titled Toxicology Testing, includes the following topics; Progress in Clinical Toxicology Testing, The Prescription Drug Abuse Epidemic, Substance Abuse Among Healthcare Professionals, Pain Management Drug Testing, Ethanol Biomarkers, Newly-emerging Drugs of Abuse, Synthetic Cannabinoids, Synthetic Cathenones, Immunoassay Methodology in Drugs-of-abuse Testing, Toxicology Testing in Alternative Specimen Matrices, Principles and Procedures in Postmortem Toxicology, and Pharmacogenetics and the Future of Toxicology Testing. Advances in toxicology testing are paving the way for major improvements in the way scientists evaluate health risks posed by toxic chemicals. Toxicity tests help scientists better understand how the human body carries out normal functions that are key to maintaining health. Therefore, this topic is important to the field of Laboratory Medicine.

Neuropathology of Drug Addictions and Substance Misuse Volume 2

Neuropathology of Drug Addictions and Substance Misuse Volume 2
Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants and International Aspects

by Victor R. Preedy

  • Publisher : Academic Press
  • Release : 2016-03-25
  • Pages : 1182
  • ISBN : 0128003758
  • Language : En, Es, Fr & De
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Neuropathology of Drug Addictions and Substance Misuse, Volume 2: Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants and International Aspects is the second of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. Each volume serves to update the reader’s knowledge on the broader field of addiction as well as to deepen understanding of specific addictive substances. Volume 2 addresses stimulants, club and dissociative drugs, hallucinogens, and inhalants and solvents. Each section provides data on the general, molecular and cellular, and structural and functional neurological aspects of a given substance, with a focus on the adverse consequences of addictions. Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention, and treatment. However, marshalling data on the complex relationships between addictions is difficult due to the myriad material and substances. Offers a modern approach to understanding the pathology of substances of abuse, offering an evidence-based ethos for understanding the neurology of addictions Fills an existing gap in the literature by serving as a “one-stop-shopping synopsis of everything to do with the neuropathology of drugs of addiction and substance misuse Includes in each chapter: list of abbreviations, abstract, introduction, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, and full references Offers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and from the genome to whole body