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Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies

Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies
A Book

by Chi Hin Cho,Tao Hu

  • Publisher : Academic Press
  • Release : 2020-05-24
  • Pages : 240
  • ISBN : 0128199385
  • Language : En, Es, Fr & De
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Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies, Volume Eight, summarizes the molecular mechanisms of drug resistance in colorectal cancer, along with the most up-to-date therapeutic strategies available. The book discusses reasons why colorectal tumors become refractory during the progression of the disease, but also explains how drug resistance occurs during chemotherapy. In addition, users will find the current therapeutic strategies used by clinicians in their practice in treating colorectal cancer. The combination of conventional anticancer drugs with chemotherapy-sensitizing agents plays a pivotal role in improving the outcome of colorectal cancer patients, in particular those with drug-resistant cancer cells. From a clinical point-of-view, the content of this book provides clinicians with updated therapeutic strategies for a better choice of drugs for drug-resistant colorectal cancer patients. It will be a valuable source for cancer researchers, oncologists and several members of biomedical field who are dedicated to better treat patients with colorectal cancer. Presents a systemic summary of molecular mechanisms for a quick and in-depth understanding Updates current trends in the field with pioneering information on drug resistance Encompasses both basic and clinical approaches for a better understanding of unsolved problems from a holistic point-of-view

Index Medicus

Index Medicus
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2004
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy

Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy
Targeted Therapies to Reverse Resistance

by Benjamin Bonavida

  • Publisher : Springer Science & Business Media
  • Release : 2013-07-04
  • Pages : 260
  • ISBN : 1461470706
  • Language : En, Es, Fr & De
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​​​​​This volume gives the latest developments in on the mechanisms of cancer cell resistance to apoptotic stimuli, which eventually result in cancer progression and metastasis. One of the main challenges in cancer research is to develop new therapies to combat resistant tumors. The development of new effective therapies will be dependent on delineating the biochemical, molecular, and genetic mechanisms that regulate tumor cell resistance to cytotoxic drug-induced apoptosis. These mechanisms should reveal gene products that directly regulate resistance in order to develop new drugs that target these resistance factors and such new drugs may either be selective or common to various cancers. If successful, new drugs may not be toxic and may be used effectively in combination with subtoxic conventional drugs to achieve synergy and to reverse tumor cell resistance. The research developments presented in this book can be translated to produce better clinical responses to resistant tumors.

Anticancer Research

Anticancer Research
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Cancer of the Colon, Rectum, and Anus

Cancer of the Colon, Rectum, and Anus
A Book

by Alfred M. Cohen,Sidney J. Winawer

  • Publisher : McGraw-Hill Companies
  • Release : 1995
  • Pages : 1154
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The definitive most up-to-date text on the treatment of colon and rectal cancer. Written for the information needs and interest of the general surgeon, the book brings together a summary of all the relevant information on colon and rectal cancer and discussion of current controversies in additon to present in therapeutic modalities, detailed studies of diagnosis, screening, and prevention are addressed.

Mechanisms of Drug Resistance in Neoplastic Cells

Mechanisms of Drug Resistance in Neoplastic Cells
A Book

by Paul V. Woolley,Kenneth D. Tew

  • Publisher : Unknown Publisher
  • Release : 1988
  • Pages : 390
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The Mechanism and New Approach on Drug Resistance of Cancer Cells

The Mechanism and New Approach on Drug Resistance of Cancer Cells
Proceedings of the International Symposium on the Mechanism and New Approach on Drug Resistance of Cancer Cells, Sapporo, 15-17 October 1992

by Tamotsu Miyazaki,Fumimaro Takaku,Keisuke Sakurada

  • Publisher : Unknown Publisher
  • Release : 1993
  • Pages : 335
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Therapeutic approaches targetting drug resistance mechanisms have been studied in the clinical field of cancer chemotherapy, and this text contributes to the progress in clinical research on the circumvention of drug resistance.

Cancer Research

Cancer Research
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2005
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Multi-drug Resistance in Emerging and Re-emerging Diseases

Multi-drug Resistance in Emerging and Re-emerging Diseases
A Book

by Indian National Science Academy

  • Publisher : Alpha Science International, Limited
  • Release : 2000
  • Pages : 282
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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"A joint symposium on Multiple Drug resistance and Emerging Diseases, ... was organized at INSA, New Delhi from 28 February to 4 March 1999."--P. [v].

Colon Cancer Cells

Colon Cancer Cells
A Book

by Mary Pat Moyer,George Poste

  • Publisher : Unknown Publisher
  • Release : 1990
  • Pages : 554
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Medical Principles and Practice

Medical Principles and Practice
International Journal of the Kuwait University, Health Science Centre

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2005
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Journal of the National Cancer Institute

Journal of the National Cancer Institute
JNCI.

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1997
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Drug and Hormonal Resistance in Breast Cancer

Drug and Hormonal Resistance in Breast Cancer
Cellular and Molecular Mechanisms

by Robert Brent Dickson,Marc E. Lippman

  • Publisher : Ellis Horwood Limited
  • Release : 1995
  • Pages : 440
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Featuring contributions from expert authors of international standing, this book explores emerging studies on the success and/or failure of chemotherapy in breast cancer. Covers the clinical resistance of breast cancer to treatment; chemo-hormonal reactions; anti-hormonal resistance; multidrug resistance; and fu/antimetabolites. For cancer and hormonal researchers and development scientists in pharmaceuticals and biomedicine. Previously announced in 7/93 PTR Catalog.

International Journal of Oncology

International Journal of Oncology
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1996-10
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Experimental Hematology

Experimental Hematology
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2002
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Forum

Forum
Trends in Experimental and Clinical Medicine

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1993
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Growth Factors and Tumor Promotion

Growth Factors and Tumor Promotion
Implications for Risk Assessment

by R. Michael McClain,Thomas J. Slaga,Robert Le Boeuf,Henry C. Pitot

  • Publisher : Wiley-Liss
  • Release : 1995-08-11
  • Pages : 470
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Progress in Clinical and Biological Research, Volume 391 Growth Factors and Tumor Promotion Implications for Risk Assessment R. Michael McClain, Thomas J. Slaga, Robert LeBoeuf, and Henry Pitot, Editors Understanding the biological, cellular, and molecular mechanisms of growth factors in carcinogenesis is essential to predicting tumor development both in research and clinical settings. An up-to-date and much needed overview of this field, Growth Factors and Tumor Promotion: Implications for Risk Assessment presents cutting-edge work from scientists involved in all areas of oncology and cancer biology. The book presents 32 chapters exploring a wide range of specialized topics in this field. Material in the text ranges from the biological changes caused by growth factors to quantifying cancer risk based on the biological data and the carcinogen bioassay. Extensive coverage is given to the complex mechanisms of growth factors in the process of tumor progression, in addition to numerous studies involving both animal models and analogous clinical cases. Growth Factors and Tumor Promotion addresses such specific topics as: a decision tree approach for carcinogenesis risk assessment hypomethlyation of DNA: a possible epigenetic mechanism involved in tumor promotion transforming growth factor-ßs in mammary tumorigenesis genetic factors controlling skin tumor promotion in mice benzoyl peroxide: review of experimental carcinogenesis and human safety data mechanistic considerations in risk assessment for epigenetic tumor-promoting carcinogens Growth Factors and Tumor Promotion: Implications for Risk Assessment features the contributions of laboratory investigators and clinical practitioners from leading medical and research institutions around the world. It is a current, authoritative work that will be of interest to cancer researchers, pathologists, toxicologists, pharmacologists, and molecular and cellular biologists—as well as scientists working with regulatory agencies that target environmental health hazards.

Excerpta Medica

Excerpta Medica
Cancer

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1991
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Oncology Research Incorporating Anti-cancer Drug Design

Oncology Research Incorporating Anti-cancer Drug Design
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1998
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Current Opinion in Oncology

Current Opinion in Oncology
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1995
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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