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Dyneins

Dyneins
Structure, Biology and Disease

by Stephen M. King,King M. Stephen

  • Publisher : Academic Press
  • Release : 2011
  • Pages : 639
  • ISBN : 0123820049
  • Language : En, Es, Fr & De
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With an accompanying Web site showing more than 100 streaming videos of cell dynamic behavior for best comprehension of material, "Dyneins" is the only reference covering the structure, biology, and application of dynein research to human disease. From bench to bedside, this book offers research on fundamental cellular processes to researchers and clinicians across developmental biology, cell biology, molecular biology, biophysics, biomedicine, genetics, and medicine.

Dyneins

Dyneins
Structure, Biology and Disease

by Stephen M. King

  • Publisher : Unknown Publisher
  • Release : 2018
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Dyneins

Dyneins
Dynein Mechanics, Dysfunction, and Disease

by Stephen M. King

  • Publisher : Academic Press
  • Release : 2017-11-28
  • Pages : 530
  • ISBN : 0128097019
  • Language : En, Es, Fr & De
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Dyneins: Structure, Biology and Disease, Second Edition, offers a broad view of dyneins mechanics, dysfunction, and disease, providing an overview of dyneins from structure and function, to dysfunction and disease. Since the first edition, enormous strides have been taken in understanding dynein structure, its organization in the axoneme, single molecule motor mechanics, and the consequences of defects for human biology, disease, and development. To account for these enormous strides, the second edition is extensively revised. Additionally, the coverage has expanded from 24 to 42 chapters, and is now housed in two volumes. Much of the expanded coverage occurs in Volume 2 which focuses on dynein dysfunction and disease, such as the role of dynein and cancer. Volume 1 covers the history and evolution of dyneins, dyneins in ciliary biology, and cytoplasmic dynein biology, while Volume 2 covers the structure and mechanics of dynein motors and dynein dysfunction and disease. Presents a broad-based and up-to date view of dynein mechanics, dysfunction, and disease Contains approaches from genetics, molecular biology, biochemistry, and biophysics discussed Provides companion website with movies of dynamic cell behavior Includes extensive chapters written by leading, global experts

Dyneins

Dyneins
The Biology of Dynein Motors

by Stephen M. King

  • Publisher : Academic Press
  • Release : 2017-11-22
  • Pages : 684
  • ISBN : 0128097027
  • Language : En, Es, Fr & De
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Dyneins: The Biology of Dynein Motors, Second Edition, offers a broad view of dyneins from structure, composition and organization, to biology of dynein function in both cytoplasm and cilia. As the second book in a pair on this topic, these works provide an overview of dyneins, from structure and function, to dysfunction and disease. Since the first edition, enormous strides have been taken in understanding dynein structure, its organization in the axoneme, single molecule motor mechanics and the consequences of defects for human biology, disease and development. This second edition is extensively revised, with coverage expanded from 24 to 42 chapters. Much of the expanded coverage occurs in Volume Two on dynein dysfunction and disease, such as the role of dynein and cancer, while Volume One covers the history and evolution of dyneins, dyneins in ciliary biology and cytoplasmic dynein biology. Presents a broad-based, up-to date view of the biology of dynein motors Discusses approaches from genetics, molecular biology, biochemistry and biophysics Includes a companion website with movies of dynamic cell behavior Covers the topic in comprehensive chapters written by world experts

Handbook of Dynein (Second Edition)

Handbook of Dynein (Second Edition)
A Book

by Keiko Hirose

  • Publisher : CRC Press
  • Release : 2019-05-28
  • Pages : 420
  • ISBN : 0429667434
  • Language : En, Es, Fr & De
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Dyneins are molecular motors that are involved in various cellular processes, such as cilia and flagella motility, vesicular transport, and mitosis. Since the first edition of this book was published in 2012, there has been a significant breakthrough: the crystal structures of the motor domains of cytoplasmic dynein have been solved and the previously unknown details of this huge and complex molecule have been unveiled. This new edition contains 14 chapters written by researchers in the US, Europe, and Asia, including 3 new chapters that incorporate new fields. The other chapters have also been substantially updated. Compared with the earlier edition, this book focuses more on the motile mechanisms of dynein, especially by biophysical methods such as cryo-EM, X-ray crystallography, and single-molecule nanometry. It is a major handbook for frontline researchers as well as for advanced students studying cell biology, molecular biology, biochemistry, biophysics, and structural biology.

Cilia: Motors and Regulation

Cilia: Motors and Regulation
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2009-12-01
  • Pages : 400
  • ISBN : 9780080961071
  • Language : En, Es, Fr & De
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Along with its companion volume on axonemal dynein-mediated motility, this book provides researchers with a comprehensive and up-to-date source of methods for the analysis cilia and flagella, focusing primarily on approaches that have been devised or significantly extended since the last volume of Methods in Cell Biology on this topic (volume 47, 1995). Edited by Stephen M. King and Gregory J. Pazour, the newest installment of this highly acclaimed serial will serve as an essential addition to the study of cilia and flagella. * Covers protocols for cilia and flagella across systems and species * Both classic and state-of-the-art methods readily adaptable across model systems, and designed to last the test of time * Relevant to clinicians interested in respiratory disease, male infertility, and other syndromes who need to learn biochemical, molecular, and genetic approaches to studying cilia, flagella, and related structures

Molecular Biology of Assemblies and Machines

Molecular Biology of Assemblies and Machines
A Book

by Alasdair Steven,Wolfgang Baumeister,Louise N. Johnson,Richard N. Perham

  • Publisher : Garland Science
  • Release : 2016-02-18
  • Pages : 880
  • ISBN : 1000064905
  • Language : En, Es, Fr & De
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Molecular Biology of Assemblies and Machines presents a comprehensive narrative describing the structures of macromolecular complexes and how they assemble and interact. Richly illustrated, it is written for advanced undergraduates, graduate students, and researchers in biochemistry, structural biology, molecular biology, biophysics, cell biology,

Cilia: Structure and Motility

Cilia: Structure and Motility
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2009-11-27
  • Pages : 344
  • ISBN : 9780080961064
  • Language : En, Es, Fr & De
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Along with its companion volume on intraflagellar transport, this book provides researchers with a comprehensive and up-to-date source of methods for the analysis cilia and flagella, focusing primarily on approaches that have been devised or significantly extended since the last volume of Methods in Cell Biology on this topic (volume 47, 1995). Edited by Stephen M. King and Gregory J. Pazour, the newest installment of this highly acclaimed serial will serve as an essential addition to the study of cilia and flagella. * Covers protocols for cilia and flagella across systems and species * Both classic and state-of-the-art methods readily adaptable across model systems, and designed to last the test of time * Relevant to clinicians interested in respiratory disease, male infertility, and other syndromes who need to learn biochemical, molecular, and genetic approaches to studying cilia, flagella, and related structures

Cilia

Cilia
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2013-03-12
  • Pages : 472
  • ISBN : 0123984866
  • Language : En, Es, Fr & De
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This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers cilia and includes chapters on such topics as electron microscopy of IFT in cilia and flagella, radial spoke isolation and assays, and biomechanical measurements of kinocilium. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers cilia Contains chapters on such topics as electron microscopy of IFT in cilia and flagella, radial spoke isolation and assays, and biomechanical measurements of kinocilium

Retrovirus-Cell Interactions

Retrovirus-Cell Interactions
A Book

by Leslie Parent

  • Publisher : Academic Press
  • Release : 2018-08-09
  • Pages : 528
  • ISBN : 0128111933
  • Language : En, Es, Fr & De
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Retrovirus-Cell Interactions provides an up-to-date review of the interactions between retroviruses and the cells they infect, offering a comprehensive understanding of how retroviruses hijack cellular factors to facilitate virus replication. Drugs targeting viral enzymes have been developed to treat HIV; the next challenge is to inhibit virus-cell interactions as next generation treatment strategies. Organized according to the retrovirus' replication cycle, this book does not focus exclusively on HIV, but rather includes important findings in other retroviral systems, including animal retroviruses, retrotransposons, and endogenous retroelements to allow broad comparisons on important commonalities and differences. Provides a valuable starting point for people who want to develop a detailed understanding of retroviral replication Includes future-thinking strategies, such as next-generation treatment and anti-retroviral therapeutics Features important commonalities and differences among retroviral systems

New Approaches to Study Ciliopathies and Centrioles-Related Genetic Disorders

New Approaches to Study Ciliopathies and Centrioles-Related Genetic Disorders
A Book

by Carlo Iomini,Sonia Mulero Navarro,Jose Maria Carvajal-Gonzalez

  • Publisher : Frontiers Media SA
  • Release : 2020-10-11
  • Pages : 129
  • ISBN : 2889661407
  • Language : En, Es, Fr & De
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Principles of Molecular Medicine

Principles of Molecular Medicine
A Book

by Marschall S. Runge,Cam Patterson

  • Publisher : Springer Science & Business Media
  • Release : 2007-11-18
  • Pages : 1268
  • ISBN : 159259963X
  • Language : En, Es, Fr & De
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The concept of molecular medicine dates back to Linus means that there are many new opportunities and challenges Pauling, who in the late 1940s and early 1950s generalized for clinical medicine. One of the effects of the completion of from the ideas that came from the study of the sickle cell the Human Genome Project is the increasing application of hemoglobin molecule. With the first cloning of human genes the fields of molecular biology and genetics to the und- about 1976, molecular genetics took the molecular perspec- standing and management of common diseases. Assimi- tive on disease to the level of DNA. The term molecular tion of the new developments since the first edition has been medicine achieved wide currency in the 1980s with the ably accomplished by Drs. Runge and Patterson with the assignment of this designation to journals, at least one soci- help of their many knowledgeable authors. ety, institutes, and academic divisions of departments of in- As was evident in the first edition, molecular genetics is ternal medicine. Undoubtedly, molecular medicine has been involved in every specialty of medicine. A recurrent theme abetted by the Human Genome Project, which has aided in that edition, perhaps even more striking in the present one, greatly in the molecular characterization of disease.

International Review of Cell and Molecular Biology

International Review of Cell and Molecular Biology
A Book

by Kwang W. Jeon

  • Publisher : Academic Press
  • Release : 2012
  • Pages : 340
  • ISBN : 0123943051
  • Language : En, Es, Fr & De
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International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Impact factor for 2009: 6.088. Authored by some of the foremost scientists in the field Provides up-to-date information and directions for future research Valuable reference material for advanced undergraduates, graduate students and professional scientists

Biochemistry

Biochemistry
A Book

by Reginald H. Garrett,Charles M. Grisham

  • Publisher : Cengage Learning
  • Release : 2016-02-11
  • Pages : 1280
  • ISBN : 1305886895
  • Language : En, Es, Fr & De
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Continuing Garrett and Grisham's innovative conceptual and organizing Essential Questions framework, BIOCHEMISTRY guides students through course concepts in a way that reveals the beauty and usefulness of biochemistry in the everyday world. Offering a balanced and streamlined presentation, this edition has been updated throughout with new material and revised presentations. For the first time, this book is integrated with OWL, a powerful online learning system for chemistry with book-specific end-of-chapter material that engages students and improves learning outcomes. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.

23rd Annual Conference of the German Crystallographic Society, March 16–19, 2015, Göttingen, Germany

23rd Annual Conference of the German Crystallographic Society, March 16–19, 2015, Göttingen, Germany
A Book

by Anonim

  • Publisher : Walter de Gruyter GmbH & Co KG
  • Release : 2015-04-28
  • Pages : 155
  • ISBN : 3110415372
  • Language : En, Es, Fr & De
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Zeitschrift für Kristallographie. Supplement Volume 35 presents the complete Abstracts of all contributions to the 23rd Annual Conference of the German Crystallographic Society in Göttingen (Germany) 2015: -Plenary Talks-Microsymposia-Poster Session Supplement Series of Zeitschrift für Kristallographie publishes Abstracts of international conferences on the interdisciplinary field of crystallography.

Animal Models in Medicine and Biology

Animal Models in Medicine and Biology
A Book

by Eva Tvrdá,Sarat Chandra Yenisetti

  • Publisher : BoD – Books on Demand
  • Release : 2020-04-08
  • Pages : 246
  • ISBN : 1838800115
  • Language : En, Es, Fr & De
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Thanks to animal models, our knowledge of biology and medicine has increased enormously over the past decades, leading to significant breakthroughs that have had a direct impact on the prevention, management and treatment of a wide array of diseases.This book presents a comprehensive reference that reflects the latest scientific research being done in a variety of medical and biological fields utilizing animal models. Chapters on Drosophila, rat, pig, rabbit, and other animal models reflect frontier research in neurology, psychiatry, cardiology, musculoskeletal disorders, reproduction, chronic diseases, epidemiology, and pain and inflammation management. Animal Models in Medicine and Biology offers scientists, clinicians, researchers and students invaluable insights into a wide range of issues at the forefront of medical and biological progress.

Biomedical Index to PHS-supported Research: pt. A. Subject access A-H

Biomedical Index to PHS-supported Research: pt. A. Subject access A-H
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1993
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Protein Trafficking in Neurons

Protein Trafficking in Neurons
A Book

by Andrew J. Bean

  • Publisher : Elsevier
  • Release : 2006-10-27
  • Pages : 464
  • ISBN : 9780080465890
  • Language : En, Es, Fr & De
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The efficient delivery of cellular constituents to their proper location is of fundamental importance for all cells and is of particular interest to neuroscientists, because of the unique functions and complex architecture of neurons. Protein Trafficking in Neurons examines mechanisms of protein trafficking and the role of trafficking in neuronal functioning from development to plasticity to disease. The book is divided into seven sections that review mechanisms of protein transport, the role of protein trafficking in synapse formation, exo- and endocytosis, transport of receptors, trafficking of ion channels and transporters, comparison of trafficking mechanisms in neuronal vs. non-neuronal cell types, and the relationship between trafficking and neuronal diseases such as Alzheimer's, Huntington's and Prion Diseases. Provides a comprehensive examination of membrane/protein movement in neuronal function Sections on synapse development, synaptic transmission, and the role of trafficking in neurological disease Includes a focus on Molecular Mechanisms Illustrated with color summary pictures The only book examining protein trafficking and its functional implications, written by leaders in the field

Mechanobiology in Health and Disease

Mechanobiology in Health and Disease
A Book

by Stefaan Verbruggen

  • Publisher : Academic Press
  • Release : 2018-08-09
  • Pages : 527
  • ISBN : 0128129530
  • Language : En, Es, Fr & De
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Mechanobiology in Health and Disease brings together contributions from leading biologists, clinicians, physicists and engineers in one convenient volume, providing a unified source of information for researchers in this highly multidisciplinary area. Opening chapters provide essential background information on cell mechanotransduction and essential mechanobiology methods and techniques. Other sections focus on the study of mechanobiology in healthy systems, including bone, tendons, muscles, blood vessels, the heart and the skin, as well as mechanobiology studies of pregnancy. Final chapters address the nascent area of mechanobiology in disease, from the study of bone conditions, skin diseases and heart diseases to cancer. A discussion of future perspectives for research completes each chapter in the volume. This is a timely resource for both early-career and established researchers working on mechanobiology. Provides an essential digest of primary research from many fields and disciplines in one convenient volume Covers both experimental approaches and descriptions of mechanobiology problems from mathematical and numerical perspectives Addresses the hot topic of mechanobiology in disease, a particularly dynamic field of frontier science

Karp's Cell and Molecular Biology

Karp's Cell and Molecular Biology
A Book

by Gerald Karp,Janet Iwasa,Wallace Marshall

  • Publisher : John Wiley & Sons
  • Release : 2020-02-19
  • Pages : 944
  • ISBN : 1119598249
  • Language : En, Es, Fr & De
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Karp’s Cell and Molecular Biology delivers a concise and illustrative narrative that helps students connect key concepts and experimentation, so they better understand how we know what we know in the world of cell biology. This classic text explores core concepts in considerable depth, often adding experimental detail. It is written in an inviting style and at mid-length, to assist students in managing the plethora of details encountered in the Cell Biology course. The 9th Edition includes two new sections and associated assessment in each chapter that show the relevance of key cell biology concepts to plant cell biology and bioengineering.