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Cardiac Energy Metabolism in Health and Disease

Cardiac Energy Metabolism in Health and Disease
A Book

by Gary D. Lopaschuk,Naranjan S. Dhalla

  • Publisher : Springer
  • Release : 2014-08-22
  • Pages : 295
  • ISBN : 1493912275
  • Language : En, Es, Fr & De
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The heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP. The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy and any change in this energy supply can seriously compromise cardiac function. It has emerged that alterations in cardiac energy metabolism are a major contributor to the development of a number of different forms of heart disease. It is also now known that optimizing energy metabolism in the heart is a viable and important approach to treating various forms of heart disease. Cardiac Energy Metabolism in Health and Disease describes the research advances that have been made in understanding what controls cardiac energy metabolism at molecular, transcriptional and physiological levels. It also describes how alterations in energy metabolism contribute to the development of heart dysfunction and how optimization of energy metabolism can be used to treat heart disease. The topics covered include a discussion of the effects of myocardial ischemia, diabetes, obesity, hypertrophy, heart failure, and genetic disorders of mitochondrial oxidative metabolism on cardiac energetics. The treatment of heart disease by optimizing energy metabolism is also discussed, which includes increasing overall energy production as well as increasing the efficiency of energy production and switching energy substrate preference of the heart. This book will be a valuable source of information to graduate students, postdoctoral fellows, and investigators in the field of experimental cardiology as well as biochemists, physiologists, pharmacologists, cardiologists, cardiovascular surgeons and other health professionals.

Heart Failure

Heart Failure
A Companion to Braunwald's Heart Disease

by Douglas L. Mann

  • Publisher : W B Saunders Company
  • Release : 2004
  • Pages : 812
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Provides readers with a comprehensive bench-to-bench overview of the field of heart failure. Every attempt has been made to include novel chapters that have not heretofore been covered in traditional textbooks on heart failure. For example, one chapter addresses the new and emerging area of sleep-disordered breathing and heart. There are also unique chapters on the science and art of developing heart failure guidelines, as well as a chapter on clinical trial design in heart failure.

Research Awards Index

Research Awards Index
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1982
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Diabetes Literature Index

Diabetes Literature Index
Index issue

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1972
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The Sinatra Solution

The Sinatra Solution
Metabolic Cardiology: Easyread Large Bold Edition

by Stephen T. Sinatra, M.D.

  • Publisher : ReadHowYouWant.com
  • Release : 2009-04-24
  • Pages : 512
  • ISBN : 1442975016
  • Language : En, Es, Fr & De
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Board-certified cardiologist Dr. Stephen T. Sinatra discusses the importance of energy metabolism on cardiovascular health and the positive impact these three energy-supplying nutrients have on the cardiovascular system. He guides you through the basics of energy metabolism and cardiac bioenergetics, and clearly explains the role of coenzyme Q10, L-carnitine, and D-ribose in the body and specifically how they affect your heart health. He also provides concise and informative examples of case histories and scientific studies that are testament to the important contribution the supplemental use of these energy-supplying nutrients make in the lives of people with heart disease every day.

Biomedical Index to PHS-supported Research: pt. A. Subject access A-H

Biomedical Index to PHS-supported Research: pt. A. Subject access A-H
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1993
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Diabetes Literature Index

Diabetes Literature Index
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1979
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Pharmacology of the Failing Human Heart

Pharmacology of the Failing Human Heart
A Book

by John McMichael

  • Publisher : Unknown Publisher
  • Release : 1950
  • Pages : 63
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Excerpta Medica. Section 6: Internal Medicine

Excerpta Medica. Section 6: Internal Medicine
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1969
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Congestive Heart Failure

Congestive Heart Failure
Mechanisms, Evaluation, and Treatment

by Dean T. Mason

  • Publisher : Butterworth-Heinemann
  • Release : 1976
  • Pages : 448
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Grape Phytochemical Intake Alters Heart Failure Pathogenesis and Cardiac Gene Transcription/translation

Grape Phytochemical Intake Alters Heart Failure Pathogenesis and Cardiac Gene Transcription/translation
A Book

by E. Mitchell Seymour

  • Publisher : Unknown Publisher
  • Release : 2009
  • Pages : 282
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Changing Concepts in Cardiovascular Disease

Changing Concepts in Cardiovascular Disease
A Book

by Henry I. Russek,Burton L. Zohman,American College of Cardiology

  • Publisher : Williams & Wilkins
  • Release : 1972
  • Pages : 469
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Angiologie / Aufsätze.

Annual Review of Medicine

Annual Review of Medicine
Selected Topics in the Clinical Sciences

by Cecil H. Coggins

  • Publisher : Annual Reviews
  • Release : 1996
  • Pages : 596
  • ISBN : 9780824305475
  • Language : En, Es, Fr & De
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Medicine & Science in Sports & Exercise Volume 33

Medicine & Science in Sports & Exercise Volume 33
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2001
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Canadian Journal of Physiology and Pharmacology

Canadian Journal of Physiology and Pharmacology
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2005
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Myocardial High-energy Phosphate Metabolism and Creatine Kinase Alterations in Hearts with Congestive Heart Failure

Myocardial High-energy Phosphate Metabolism and Creatine Kinase Alterations in Hearts with Congestive Heart Failure
A Book

by Yun Ye

  • Publisher : Unknown Publisher
  • Release : 2002
  • Pages : 328
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Chest

Chest
Official Publication of the American College of Chest Physicians

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Monograph

Monograph
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1960
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Neonatal Heart Disease

Neonatal Heart Disease
A Book

by William F. Friedman,Michael Lesch,Edmund H. Sonnenblick

  • Publisher : Grune & Stratton, Incorporated
  • Release : 1973
  • Pages : 299
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Pharmacotherapy of Heart Failure

Pharmacotherapy of Heart Failure
A Book

by Suresh Kumar Gupta

  • Publisher : Anshan Pub
  • Release : 2005
  • Pages : 270
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Heart failure has been traditionally explained as a reduction in cardiac pumping capacity, caused by problems in the blood. Till now the therapy prescribed has been symptomatic, involving the use of diuretics, muscular stimulation and blood vessel relaxants. But recent research has focussed on the circumstances leading up to heart failure, which includes abnormal hemodynamics, atherosclerosis, dietary and nutritional anomalies, obesity, immunity and other metabolic disorders. This book brings together such research in one volume, including molecular and cellular aspects of heart failure and its pathophysiology. It is a significant contribution to the understanding and prevention of heart failure, and will be welcomed by cardiologists, pharmacologists, biochemists, and all those who practice and research the subject. The contributors from around the world include Australia, Brazil, Canada, Denmark, India, and USA.