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Engineered Nanopores for Bioanalytical Applications

Engineered Nanopores for Bioanalytical Applications
A Book

by Joshua B. Edel,Tim Albrecht

  • Publisher : William Andrew
  • Release : 2013-03-19
  • Pages : 192
  • ISBN : 143773474X
  • Language : En, Es, Fr & De
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Engineered Nanopores for Bioanalytical Applications is the first book to focus primarily on practical analytical applications of nanopore development. These nanoscale analytical techniques have exciting potential because they can be used in applications such as DNA sequencing, DNA fragment sizing, DNA/protein binding, and protein/protein binding. This book provides a solid professional reference on nanopores for readers in academia, industry and engineering and biomedical fields. In addition, the book describes the instrumentation, fabrication, and experimental methods necessary to carry out nanopore-based experiments for developing new devices. Includes application case studies for detection, identification and analysis of biomolecules and related functional nanomaterials Introduces the techniques of manufacturing solid state materials with functional nanopores Explains the use of nanopores in DNA sequencing and the wider range of applications from environmental monitoring to forensics

Nanopores for Bioanalytical Applications

Nanopores for Bioanalytical Applications
Proceedings of the International Conference

by Joshua Edel,Tim Albrecht

  • Publisher : Royal Society of Chemistry
  • Release : 2012-09-05
  • Pages : 150
  • ISBN : 1849735271
  • Language : En, Es, Fr & De
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Bioanalytical applications in nanopores are an exciting field of research which have seen rapid development over the last ten plus years. This book focuses uniquely on this research area providing an insight from the world leading experts in the area. Based on the proceedings of the 1st International Conference on Nanopores for Bioanalytical Applications (Lanzarote, 2012), it will provide a snapshot of this exciting field for the nanopores community. It describes the latest experimental and fabrication protocols necessary to carry out nanopore-based experiments and covers a wide variety of topics. These include: biological pores, solid state pores, hybrid structures, fundamental aspects, work on the underlying (bio)physics and applications in biosensing and DNA sequencing. The multidisciplinary approach to this topic makes the book suitable for readers in both academia and industry.

Confining Electrochemistry to Nanopores

Confining Electrochemistry to Nanopores
A Book

by Yi-Tao Long

  • Publisher : Royal Society of Chemistry
  • Release : 2020-10-30
  • Pages : 256
  • ISBN : 1788012712
  • Language : En, Es, Fr & De
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The nanopore provides a highly electrochemically confined space within which single-molecule characteristics can be efficiently converted into measurable electrochemical signatures with high temporal and current resolution. Aimed at developing the concept of the electrochemical confined space in analysing single molecules, this book serves as a stepping-stone to many exciting discoveries in nanopore-based analysis of biological processes and chemical reactions in confined space. The field of nanopore sensors is growing rapidly, but there have been no new books on nanopore technology that provide an overview of the research on nanopore-based sensing until now. The book provides a good source of nanopore studies for researchers interested in and working in the general areas of electrochemistry and nanobiotechnology, especially on nanopore sensors.

Single Molecule and Single Cell Sequencing

Single Molecule and Single Cell Sequencing
A Book

by Yutaka Suzuki

  • Publisher : Springer
  • Release : 2019-04-09
  • Pages : 150
  • ISBN : 9811360375
  • Language : En, Es, Fr & De
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This book presents an overview of the recent technologies in single molecule and single cell sequencing. These sequencing technologies are revolutionizing the way of the genomic studies and the understanding of complex biological systems. The PacBio sequencer has enabled extremely long-read sequencing and the MinION sequencer has made the sequencing possible in developing countries. New developments and technologies are constantly emerging, which will further expand sequencing applications. In parallel, single cell sequencing technologies are rapidly becoming a popular platform. This volume presents not only an updated overview of these technologies, but also of the related developments in bioinformatics. Without powerful bioinformatics software, where rapid progress is taking place, these new technologies will not realize their full potential. All the contributors to this volume have been involved in the development of these technologies and software and have also made significant progress on their applications. This book is intended to be of interest to a wide audience ranging from genome researchers to basic molecular biologists and clinicians.

Chemically Modified Nanopores and Nanochannels

Chemically Modified Nanopores and Nanochannels
A Book

by Mario Tagliazucchi,Igal Szleifer

  • Publisher : William Andrew
  • Release : 2016-08-29
  • Pages : 226
  • ISBN : 0323413625
  • Language : En, Es, Fr & De
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Chemically Modified Nanopores and Nanochannels is devoted to chemically modified nanopores and nanochannels, and covers the fundamentals of transport in chemically modified systems, an account of the different preparation and characterization techniques of chemically modified nanopores, their applications, and case studies. The book is designed for materials and biomaterials scientists, biomedical engineers, chemists, and chemical engineers who are interested in designing and utilizing processes to synthesize, modify, characterize, use, and model nanopores. The strong chemical focus of the book differentiates it from other books published on nanopores, which traditionally focus either on physics, biophysics, and nanofabrication (solid-state nanopores) or biophysics and biology (biological ion channels and pores). Explains how the chemical modification of nanopores and nanochannels can be used in filtration, membranes, and sensing Provides advanced coverage of novel synthetic applications Focuses on the latest developments in nanopore and nanochannel engineering Presents an account of the different preparation and characterization techniques of chemically modified nanopores, their applications, and case studies

Handbook of Silicon Based MEMS Materials and Technologies

Handbook of Silicon Based MEMS Materials and Technologies
A Book

by Markku Tilli,Mervi Paulasto-Krockel,Teruaki Motooka,Veikko Lindroos

  • Publisher : William Andrew
  • Release : 2015-09-02
  • Pages : 826
  • ISBN : 0323312233
  • Language : En, Es, Fr & De
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The Handbook of Silicon Based MEMS Materials and Technologies, Second Edition, is a comprehensive guide to MEMS materials, technologies, and manufacturing that examines the state-of-the-art with a particular emphasis on silicon as the most important starting material used in MEMS. The book explains the fundamentals, properties (mechanical, electrostatic, optical, etc.), materials selection, preparation, manufacturing, processing, system integration, measurement, and materials characterization techniques, sensors, and multi-scale modeling methods of MEMS structures, silicon crystals, and wafers, also covering micromachining technologies in MEMS and encapsulation of MEMS components. Furthermore, it provides vital packaging technologies and process knowledge for silicon direct bonding, anodic bonding, glass frit bonding, and related techniques, shows how to protect devices from the environment, and provides tactics to decrease package size for a dramatic reduction in costs. Provides vital packaging technologies and process knowledge for silicon direct bonding, anodic bonding, glass frit bonding, and related techniques Shows how to protect devices from the environment and decrease package size for a dramatic reduction in packaging costs Discusses properties, preparation, and growth of silicon crystals and wafers Explains the many properties (mechanical, electrostatic, optical, etc.), manufacturing, processing, measuring (including focused beam techniques), and multiscale modeling methods of MEMS structures Geared towards practical applications rather than theory

Nanofluidics

Nanofluidics
A Book

by Joshua Edel,Aleksandar Ivanov,MinJun Kim

  • Publisher : Royal Society of Chemistry
  • Release : 2016-11-11
  • Pages : 320
  • ISBN : 1849735239
  • Language : En, Es, Fr & De
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There has been significant growth in the field of nanofluidics, where nanoscale analytical instruments employ micromachined features and are able to manipulate fluid samples with high precision and efficiency and have many advantages over their conventional (larger) analogues. The new edition of Nanofluidics has been fully revised and updated with the latest advancements and applications. With a focus on bioanalysis, specific applications are given with case studies. The end of each chapter now also features a methodology section to explain experimental protocols and “tips and tricks”. The editors draw on an international authorship and provide a handbook for the community. Written at an accessible level the book is suitable for both experts and non-experts alike.

Nanofluidics (Second Edition)

Nanofluidics (Second Edition)

by Joshua Edel,Aleksandar Ivanov,MinJun Kim

  • Publisher : Royal Society of Chemistry
  • Release : 2016-11-18
  • Pages : 339
  • ISBN : 1849734046
  • Language : En, Es, Fr & De
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Lipid-Based Nanocarriers for Drug Delivery and Diagnosis

Lipid-Based Nanocarriers for Drug Delivery and Diagnosis
A Book

by Muhammad Raza Shah,Muhammad Imran,Shafi Ullah

  • Publisher : William Andrew
  • Release : 2017-06-07
  • Pages : 372
  • ISBN : 0323527302
  • Language : En, Es, Fr & De
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Lipid-Based Nanocarriers for Drug Delivery and Diagnosis explores the present state of widely used lipid-based nanoparticulate delivery systems, such as solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC), nanoliposomes, micelles, nanoemulsions, nanosuspensions and lipid nanotubes. The various types of lipids that can be exploited for drug delivery and their chemical composition and physicochemical characteristics are reviewed in detail, along with their characterization aspects and effects of their dimensions on drug delivery systems behavior in-vitro and in-vivo. The book covers the effective utilization of these lipids based systems for controlled and targeted delivery of potential drugs/genes for enhanced clinical efficacy. Provides the present state of widely used lipid-based nanoparticulate delivery systems Explores how lipid-based nanocarriers improve drug delivery safety Describes the nanoformulation design and the preparation methods of lipid-based nanocarriers

Engineering Stem Cells For Tissue Regeneration

Engineering Stem Cells For Tissue Regeneration
A Book

by Li Song,L'heureux Nicolas,Huang Ngan

  • Publisher : World Scientific
  • Release : 2017-11-24
  • Pages : 568
  • ISBN : 9813147768
  • Language : En, Es, Fr & De
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Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs, including cardiovascular, musculoskeletal, neurological and skin tissues. The technology platforms for studying and engineering stem cells, such as hydrogel and biomaterials development, microfluidics system and microscale patterning, are also illustrated. Regulatory challenges and quality control for clinical translation are also detailed. This book provides an comprehensive update on the advancement in the field of stem cells and regenerative medicine, and serves as a valuable resource for both researchers and students. Contents: Tissue Engineering: From Basic Biology to Cell-Based Applications (R M Nerem)Recent Advances and Future Perspectives on Somatic Cell Reprogramming (K-Y Kim & I-H Park)Hematopoietic Stem Cells (J J Trowbridge)Mesenchymal Stem Cells for Tissue Regeneration (N F Huang & S Li)Delivery Vehicles for Deploying Mesenchymal Stem Cells in Tissue Repair (M S Friedman & J K Leach)Stem Cells for Cardiac Tissue Engineering (J L Young et al.)Cardiovascular System: Stem Cells in Tissue-Engineered Blood Vessels (R Sawh-Martinez et al.)Stem Cells for Vascular Regeneration: An Engineering Approach (L E Dickinson & S Gerecht)Stem Cells and Wound Repair (S H Ko et al.)Engineering Cartilage: From Materials to Small Molecules (J M Coburn & J H Elisseeff)Adult Stem Cells for Articular Cartilage Tissue Engineering (S Saha et al.)Stem Cells for Disc Repair (A A Allon et al.)Skeletal Tissue Engineering: Progress and Prospects (N J Panetta et al.)Clinical Applications of a Stem Cell Based Therapy for Oral Bone Reconstruction (B McAllister & K Haghighat)Therapeutic Strategies for Repairing the Injured Spinal Cord Using Stem Cells (M S Beattie & J C Bresnahan)Potential of Tissue Engineering and Neural Stem Cells in the Understanding and Treatment of Neurodegenerative Diseases (C Auclair-Daigle & F Berthod)High-Throughput Systems for Stem Cell Engineering (D A Brafman et al.)Microscale Technologies for Tissue Engineering and Stem Cell Differentiation (J W Nichol et al.)Quality Control of Autologous Cell- and Tissue-Based Therapies (N Dusserre et al.)Regulatory Challenges for Cell-Based Therapeutics (T McAllister et al.) Readership: Life science scientists; biomedical researchers; cell biologists; academics, postgraduate students and advanced undergraduate students in cell biology, biochemistry and genetics; surgeons; clinicians; biotechnology and pharmaceutical industry professionals. Keywords: Stem Cells;Tissue Engineering;Regenerative Medicine;Biotechnology;Cell EngineeringReview:0

Biocompatible Graphene for Bioanalytical Applications

Biocompatible Graphene for Bioanalytical Applications
A Book

by Yuwei Hu,Fenghua Li,Dongxue Han,Li Niu

  • Publisher : Springer
  • Release : 2014-12-04
  • Pages : 116
  • ISBN : 3662456958
  • Language : En, Es, Fr & De
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This book highlights the latest advances in the use of graphene and bio-compatible-material-decorated graphene to detect various targets (e.g. DNA, RNA, amino acids, peptides, proteins, enzymes, antigens, glucose, DA, AA, UA, ATP, NADH, gas, ions, etc.). It focuses on the specific interaction of these substances with graphene (or modified graphene) and the efficient transduction of the target recognition event into detectable signals via various techniques. Particular emphasis is given to well-designed strategies for constructing graphene-based platforms and target determination. It also covers other bio-analytical applications including cellular imaging, drug delivery and bacteria inhibition, before turning to a discussion of future challenges and prospects of graphene in bio-analytical applications. This book is intended for researchers working in the fields of analytical chemistry, nanomaterials and biomedical engineering. Li Niu is a Professor at the State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences.

Advanced Materials and Techniques for Biosensors and Bioanalytical Applications

Advanced Materials and Techniques for Biosensors and Bioanalytical Applications
A Book

by Pranab Goswami

  • Publisher : CRC Press
  • Release : 2020-11-04
  • Pages : 302
  • ISBN : 1000194736
  • Language : En, Es, Fr & De
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Bioanalytical science and its technological subdomain, biosensors, are ever-evolving subjects, striving for rapid improvement in terms of performance and expanding the target range to meet the vast societal and market demands. The key performance factors for a biosensor that drive the research are selectivity, sensitivity, response time, accuracy, and reproducibility, with additional requirements of its portability and inexpensive nature. These performance factors are largely governed by the materials and techniques being used in these bioanalytical platforms. The selection of materials to meet these requirements is critical, as their interaction or involvement with the biological recognition elements should initiate or improve these performance factors. The technique discussed primarily applies to transducers involved in converting a biochemical signal to optical or electrical signals. Over the years, the emergence of novel materials and techniques has drastically improved the performance of these bioanalytical systems, enabling them to expand their analytical horizon. These advanced materials and techniques are central to modern bioanalytical and biosensor research. Advanced Materials and Techniques for Biosensors and Bioanalytical Applications provides a comprehensive review of the subject, including a knowledge platform for both academics and researchers. Considering biosensors as a central theme to this book, an outline on this subject with background principles has been included, with a scope of extending the utility of the book to coursework in graduate and postgraduate schools. Features: • Basic principles on different classes of biosensors, recent advances and applications • Smart materials for biosensors and other rapid, portable detection devices • Metal nanoparticles and nanocrystals for analytical applications • Carbon-based nanoparticles and quantum dots for sensing applications • Nanozymes as potential catalysts for sensing applications • Bioelectrochemiluminescence and photoelectrochemical-based biosensors • Paper electronics and paper-based biosensors • Microbial biosensors: artificial intelligence, genetic engineering, and synthetic biology • Biofuel cells as a signal transduction platform • FET-based biosensors, including ISFET and BioFET This book serves as a reference for scientific investigators and a textbook for a graduate-level course in biosensors and advanced bioanalytical techniques.

Nucleic Acid Nanotechnology

Nucleic Acid Nanotechnology
A Book

by Jørgen Kjems,Elena Ferapontova,Kurt V. Gothelf

  • Publisher : Springer Science & Business Media
  • Release : 2013-10-19
  • Pages : 339
  • ISBN : 3642388159
  • Language : En, Es, Fr & De
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This volume on nucleic acid nanotechnology offers authoritative, up-to-date and comprehensive coverage of nanotechnological studies and applications of nucleic acids. It provides reviews of various aspects of nucleic acid nanotechnology, each written by an internationally leading expert in the field, and presents state-of-the-art and recent advances in nucleic acid synthetic modifications, nanoscale design, manipulation and current and future applications in bioengineering, medicine, electronics, genetic analysis, chemistry, molecular biology, surface and material sciences. It examines how nucleic acid research is merging with nanotechnology, allowing the nanoscale properties of nucleic acid to be exploited in performing challenging nanotechnological tasks, from nanorobotics and nanosensing to nucleic acid computing. This book will above all benefit anyone who is interested in nanotechnological concepts of nucleic acid design and applications, and offers a valuable resource for teaching these concepts. It is essential reading for a broad audience of scientists both in academia and industry who wish to expand their expertise on the potential of nucleic acid functions and applications.

Single Particle Studies on an Integrated Nanopore-optofluidic Chip

Single Particle Studies on an Integrated Nanopore-optofluidic Chip
A Book

by Mikhail Rudenko

  • Publisher : Unknown Publisher
  • Release : 2010
  • Pages : 512
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Nanofluidics and Microfluidics

Nanofluidics and Microfluidics
Systems and Applications

by Shaurya Prakash,Junghoon Yeom

  • Publisher : William Andrew
  • Release : 2014-01-16
  • Pages : 312
  • ISBN : 1437744702
  • Language : En, Es, Fr & De
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To provide an interdisciplinary readership with the necessary toolkit to work with micro- and nanofluidics, this book provides basic theory, fundamentals of microfabrication, advanced fabrication methods, device characterization methods and detailed examples of applications of nanofluidics devices and systems. Case studies describing fabrication of complex micro- and nanoscale systems help the reader gain a practical understanding of developing and fabricating such systems. The resulting work covers the fundamentals, processes and applied challenges of functional engineered nanofluidic systems for a variety of different applications, including discussions of lab-on-chip, bio-related applications and emerging technologies for energy and environmental engineering. The fundamentals of micro- and nanofluidic systems and micro- and nanofabrication techniques provide readers from a variety of academic backgrounds with the understanding required to develop new systems and applications. Case studies introduce and illustrate state-of-the-art applications across areas, including lab-on-chip, energy and bio-based applications. Prakash and Yeom provide readers with an essential toolkit to take micro- and nanofluidic applications out of the research lab and into commercial and laboratory applications.

Molecular- and Nano-Tubes

Molecular- and Nano-Tubes
A Book

by Oliver Hayden,Kornelius Nielsch

  • Publisher : Springer Science & Business Media
  • Release : 2011-08-04
  • Pages : 473
  • ISBN : 9781441994431
  • Language : En, Es, Fr & De
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Molecular- and Nano-Tubes summarizes recent advancements in the synthesis, fabrication and applications of tubular structures. An interdisciplinary overview of innovative science focused on tubular structures is provided. The reader is offered an overview of the different fields that molecular and nano tubes appear in, in order to learn the fundamental basics as well as the applications of these materials. This book also: Shows how nanotechnology creates novel materials by crossing the barriers between biology and material science, electronics and optics, medicine and more Demonstrates that tubes are a fundamental element in nature and used in disparate applications such as ion channels and carbon nanotubes Molecular- and Nano-Tubes is an ideal volume for researchers and engineers working in materials science and nanotechnology.

BioNanoFluidic MEMS

BioNanoFluidic MEMS
A Book

by Peter J. Hesketh

  • Publisher : Springer Science & Business Media
  • Release : 2007-11-15
  • Pages : 295
  • ISBN : 038746283X
  • Language : En, Es, Fr & De
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This book explains biosensor development fundamentals. It also initiates awareness in engineers and scientists who would like to develop and implement novel biosensors for agriculture, biomedicine, homeland security, environmental needs, and disease identification. In addition, the book introduces and lays the basic foundation for design, fabrication, testing, and implementation of next generation biosensors through hands-on learning.

Biomedical Engineering

Biomedical Engineering
From Theory to Applications

by Reza Fazel-Rezai

  • Publisher : BoD – Books on Demand
  • Release : 2011-08-29
  • Pages : 500
  • ISBN : 9533076372
  • Language : En, Es, Fr & De
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In all different areas in biomedical engineering, the ultimate objectives in research and education are to improve the quality life, reduce the impact of disease on the everyday life of individuals, and provide an appropriate infrastructure to promote and enhance the interaction of biomedical engineering researchers. This book is prepared in two volumes to introduce a recent advances in different areas of biomedical engineering such as biomaterials, cellular engineering, biomedical devices, nanotechnology, and biomechanics. It is hoped that both of the volumes will bring more awareness about the biomedical engineering field and help in completing or establishing new research areas in biomedical engineering.

Polymer Engineering

Polymer Engineering
A Book

by Bartosz Tylkowski,Karolina Wieszczycka,Renata Jastrzab

  • Publisher : Walter de Gruyter GmbH & Co KG
  • Release : 2017-09-25
  • Pages : 490
  • ISBN : 311046974X
  • Language : En, Es, Fr & De
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Polymer Engineering focuses on the preparation and application of polymers in several hot topics such as artificial photosynthesis, water purification by membrane technologies, and biodiesel production from wastewater plants. The authors not only describe the latest developments in polymer science, but also support these experimental results by computational chemistry and modelling studies.

Biomedical Engineering: Concepts, Methodologies, Tools, and Applications

Biomedical Engineering: Concepts, Methodologies, Tools, and Applications
Concepts, Methodologies, Tools, and Applications

by Management Association, Information Resources

  • Publisher : IGI Global
  • Release : 2017-07-13
  • Pages : 1463
  • ISBN : 1522531599
  • Language : En, Es, Fr & De
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Technological tools and computational techniques have enhanced the healthcare industry. These advancements have led to significant progress and novel opportunities for biomedical engineering. Biomedical Engineering: Concepts, Methodologies, Tools, and Applications is an authoritative reference source for emerging scholarly research on trends, techniques, and future directions in the field of biomedical engineering technologies. Highlighting a comprehensive range of topics such as nanotechnology, biomaterials, and robotics, this multi-volume book is ideally designed for medical practitioners, professionals, students, engineers, and researchers interested in the latest developments in biomedical technology.