Download Epigenetics and Reproductive Health Ebook PDF

Epigenetics and Reproductive Health

Epigenetics and Reproductive Health
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2020-09-12
  • Pages : 444
  • ISBN : 0128197544
  • Language : En, Es, Fr & De
GET BOOK

Epigenetics and Reproductive Health, a new volume in the Translational Epigenetics series, provides a thorough overview and discussion of epigenetics in reproduction and implications for reproductive medicine. Twenty international researchers discuss epigenetic mechanisms operating during the formation of male and female gametes, fertilization and subsequent embryo and placental development, particularly in mammals and transgenerational epigenetic inheritance. This volume also addresses aberrant epigenetic changes influencing male and female infertility, pregnancy related disorders, and those potentially linked to therapeutic manipulations and assisted reproductive technologies. Emphasis is placed on identifying biomarkers for early detection of aberrant epigenetic mechanisms. Later chapters examine the possibility of correcting these epigenetic dysfunctions, as well as current challenges and next steps in research, enabling new translational discoveries and efforts towards developing therapeutics. Thoroughly examines the influence of aberrant epigenetics during gametogenesis and embryogenesis, affecting parents, gametes and embryos, offspring and future generations Explores health outcomes for reproductive senescence, endocrine disruption, testicular cancer, prostrate cancer, breast cancer, ovarian, cancer, endometrial cancer and cervical cancers Features chapter contributions from international researchers in the field

Environmental Health Perspectives

Environmental Health Perspectives
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2006-08
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
GET BOOK

Index Medicus

Index Medicus
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2004
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
GET BOOK

Bisphenols and Male Reproductive Health

Bisphenols and Male Reproductive Health
A Book

by Arcangelo Barbonetti,Nicola Bernabò,Settimio D’Andrea,David H. Volle

  • Publisher : Frontiers Media SA
  • Release : 2020-12-10
  • Pages : 329
  • ISBN : 2889662039
  • Language : En, Es, Fr & De
GET BOOK

Epigenetics In Human Reproduction And Development

Epigenetics In Human Reproduction And Development
A Book

by Naumova Anna K,Taketo-hosotani Teruko

  • Publisher : World Scientific
  • Release : 2016-12-20
  • Pages : 304
  • ISBN : 9813144289
  • Language : En, Es, Fr & De
GET BOOK

Epigenetics is defined as heritable changes that do not affect the DNA sequence but influence gene expression. Epigenetic changes occur at the levels of DNA, histone, protein, and chromatin structures. Proper epigenetic modifications are essential for cell differentiation and function during development, while some epigenetic modifications are passed on from parents to offspring through gametes. Therefore, alterations of epigenetic states would have serious consequences for human development and health. This realization and the advent of new technologies have encouraged the advance of epigenetic studies in recent years. Nonetheless, many aspects of epigenetics, such as regulatory mechanisms and evolutional advantages, remain to be better understood. Written by 26 scientists at the forefront of epigenetics research, this book discusses the different facets of epigenetics: from gametogenesis to child development, as well as from mechanistic studies in animal models to reviews of human clinical data.

Reproductive Hazards and Military Service

Reproductive Hazards and Military Service
What are the Risks of Radiation, Agent Orange, and Gulf War Exposures? : Hearing Before the Committee on Veterans' Affairs, United States Senate, One Hundred Third Congress, Second Session, August 5, 1994

by United States,United States. Congress. Senate. Committee on Veterans' Affairs

  • Publisher : Unknown Publisher
  • Release : 1995
  • Pages : 513
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
GET BOOK

African Journal of Reproductive Health

African Journal of Reproductive Health
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2006
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
GET BOOK

Epigenetics and Human Health

Epigenetics and Human Health
Linking Hereditary, Environmental and Nutritional Aspects

by Alexander Haslberger,Sabine Greßler

  • Publisher : John Wiley & Sons
  • Release : 2011-08-24
  • Pages : 316
  • ISBN : 352764475X
  • Language : En, Es, Fr & De
GET BOOK

After first introducing the concept of epigenetics, this handbook and ready reference provides an overview of the main research on epigenetics. It adopts a multidisciplinary approach, involving molecular biology, molecular epidemiology and nutritional science, with a special focus of the book is on disease prevention and treatment. Of interest to all healthcare-related professionals as well as nutritionists, and the medical community focusing on disease prevention.

Animal Models and Human Reproduction

Animal Models and Human Reproduction
Cell and Molecular Approaches with Reference to Human Reproduction

by Heide Schatten

  • Publisher : John Wiley & Sons
  • Release : 2017-03-20
  • Pages : 600
  • ISBN : 1118881605
  • Language : En, Es, Fr & De
GET BOOK

Our knowledge of reproductive biology has increased enormously in recent years on cellular, molecular, and genetic levels, leading to significant breakthroughs that have directly benefitted in vitro fertilization (IVF) and other assisted reproductive technologies (ART) in humans and animal systems. Animal Models and Human Reproduction presents a comprehensive reference that reflects the latest scientific research being done in human reproductive biology utilizing domestic animal models. Chapters on canine, equine, cow, pig, frog, and mouse models of reproduction reflect frontier research in placental biology, ovarian function and fertility, non-coding RNAs in gametogenesis, oocyte and embryo metabolism, fertilization, cryopreservation, signal transduction pathways, chromatin dynamics, epigenetics, reproductive aging, and inflammation. Chapters on non-human primate models also highlight recent advancements into such issues as human in vitro fertilization (IVF) and assisted reproductive technologies (ART). This book offers animal scientists, reproductive biology scientists, clinicians and practitioners, invaluable insights into a wide range of issues at the forefront of human reproductive health.

Epigenetics in Human Disease

Epigenetics in Human Disease
A Book

by Trygve O. Tollefsbol

  • Publisher : Academic Press
  • Release : 2012
  • Pages : 577
  • ISBN : 0123884152
  • Language : En, Es, Fr & De
GET BOOK

Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike. Comprehensive coverage of fundamental and emergent science and clinical usage Side-by-side coverage of the basis of epigenetic diseases and their treatments Evaluation of recent epigenetic clinical breakthroughs

Encyclopedia of Reproduction

Encyclopedia of Reproduction
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2018-06-29
  • Pages : 3868
  • ISBN : 0128151455
  • Language : En, Es, Fr & De
GET BOOK

Encyclopedia of Reproduction, Second Edition comprehensively reviews biology and abnormalities, also covering the most common diseases in humans, such as prostate and breast cancer, as well as normal developmental biology, including embryogenesis, gestation, birth and puberty. Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers, from advanced undergraduate students, to research professionals. Chapters also explore the latest advances in cloning, stem cells, endocrinology, clinical reproductive medicine and genomics. As reproductive health is a fundamental component of an individual’s overall health status and a central determinant of quality of life, this book provides the most extensive and authoritative reference within the field. Provides a one-stop shop for information on reproduction that is not available elsewhere Includes extensive coverage of the full range of topics, from basic, to clinical considerations, including evolutionary advances in molecular, cellular, developmental and clinical sciences Includes multimedia and interactive teaching tools, such as downloadable PowerPoint slides, video content and interactive elements, such as the Virtual Microscope

Women's Health Wisdom

Women's Health Wisdom
Real-life Solutions from the Editors of Health Magazine

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2004
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
GET BOOK

Women's Health and Disease, Volume 1205

Women's Health and Disease, Volume 1205
A Book

by George Creatsas,George Mastorakos

  • Publisher : Wiley-Blackwell
  • Release : 2010-10-25
  • Pages : 292
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
GET BOOK

"This volume presents manuscripts stemming from the "The 7th Athens Congress on Women's Health and Disease: Gynecologic, Endocrine, and Reproductive Issues" held on September 11-13, 2008 in Athens, Greece"--Caption.

Reproductive Genetics

Reproductive Genetics
A Book

by Sean Kehoe,Lyn Chitty,Tessa Homfray

  • Publisher : RCOG
  • Release : 2009-11
  • Pages : 242
  • ISBN : 1906985162
  • Language : En, Es, Fr & De
GET BOOK

This book presents the findings of the RCOG Study Group findings on genetics underlying reproductive function.

Human Reproductive and Prenatal Genetics

Human Reproductive and Prenatal Genetics
A Book

by Peter C. K. Leung,Jie Qiao

  • Publisher : Academic Press
  • Release : 2018-08-28
  • Pages : 709
  • ISBN : 0128135719
  • Language : En, Es, Fr & De
GET BOOK

Human Reproductive and Prenatal Genetics presents the latest material from a detailed molecular, cellular and translational perspective. Considering its timeliness and potential international impact, this all-inclusive and authoritative work is ideal for researchers, students, and clinicians worldwide. Currently, there are no comprehensive books covering the field of human reproductive and prenatal genetics. As such, this book aims to be among the largest and most useful references available. Features chapter contributions from leading international scientists and clinicians Provides in-depth coverage of key topics in human reproductive and prenatal genetics, including genetic controls, fertilization and implantation, in vitro culture of the human embryo for the study of post-implantation development, and more Identifies how researchers and clinicians can implement the latest genetic, epigenetic, and –omics based approaches

DES Daughters, Embodied Knowledge, and the Transformation of Women's Health Politics in the Late Twentieth Century

DES Daughters, Embodied Knowledge, and the Transformation of Women's Health Politics in the Late Twentieth Century
A Book

by Susan E. Bell

  • Publisher : Temple University Press
  • Release : 2009-08-28
  • Pages : 232
  • ISBN : 9781592139187
  • Language : En, Es, Fr & De
GET BOOK

From the 1940s to the 1970s, millions of women were exposed prenatally to the synthetic estrogen DES, a “wonder drug” intended to prevent miscarriages. However, DES actually had damaging consequences for the women born from DES mothers. The “DES daughters” as they are known, were found to have a rare form of vaginal cancer or were infertile. They were also at risk for miscarriages, stillbirths, and ectopic pregnancies. In DES Daughters, Susan Bell recounts the experiences of this generation of “victims.” In moving, heartfelt narratives, she presents the voices of those women who developed cancer, those who were cancer-free but have concerns about becoming pregnant, and those who suffered other medical and/or reproductive difficulties. Bell examines the hierarchy of knowledge and power of scientists, doctors, and daughters, tracing the emergence of a feminist health movement. The “embodied knowledge” of these DES daughters prompted them to become advocates and form a social movement that challenged reproductive medical knowledge specifically, but also the politics of women’s health in general. Bell’s important book chronicles the history and future of these grassroots activists born out of illness, suffering, and uncertainty.

Epigenetic Epidemiology

Epigenetic Epidemiology
A Book

by Karin B. Michels

  • Publisher : Springer Science & Business Media
  • Release : 2012-01-03
  • Pages : 448
  • ISBN : 9400724942
  • Language : En, Es, Fr & De
GET BOOK

The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly incorporate epigenetic components. The relevance of epigenetic marks, such as DNA methylation, genomic imprinting, and histone modification for disease causation has yet to be fully explored. This book covers the basic concepts of epigenetic epidemiology, discusses challenges in study design, analysis, and interpretation, epigenetic laboratory techniques, the influence of of age and environmental factors on shaping the epigenome, the role of epigenetics in the developmental origins hypothesis, and provides the state of the art on the epigenetic epidemiology of various health conditions including childhood syndromes, cancer, infectious diseases, inflammation and rheumatoid arthritis, asthma, autism and other neurodevelopmental disorders, psychiatric disorders, diabetes, obesity and metabolic disorders, and atherosclerosis. With contributions from: Peter Jones, Jean-Pierre Issa, Gavin Kelsey, Robert Waterland, and many other experts in epigenetics!

Encyclopedia of Global Health

Encyclopedia of Global Health
A Book

by Yawei Zhang

  • Publisher : SAGE Publications, Incorporated
  • Release : 2008-01-09
  • Pages : 2288
  • ISBN : 9781412941860
  • Language : En, Es, Fr & De
GET BOOK

"A general reference for topics related to health worlwide, this encyclopedia is ambitious in its scope, with entries for specific diseases and conditions, geographical areas, health issues, biographical information, and organizations related to world health policy." —CHOICE "A useful, one-stop reference for health professionals and the general population alike that speaks to important changes and issues in global health; a foundation of knowledge essential for any library." —Library Journal The contemporary understanding of global health is complicated and extends to all ends of the Earth and beyond. From the health effects of global warming to the implications of single nucleotide differences on disease, the factors that impact global health are extremely diverse and are changing constantly. As new scientific advances are made, as new policies are implemented, as wars are waged and peace agreements signed, or as new strains of infectious diseases evolve, the state of global health changes. The Encyclopedia of Global Health is a comprehensive, one stop reference to a broad array of health topics worldwide. Encompassing four volumes with more than 1,200 articles, the Encyclopedia covers all aspects of health, including physical and mental health entries, biographies of major doctors and researchers, profiles of medical institutions, organizations, and corporations, descriptions of drugs and operations, articles on national health policies, and thematic health topics in the humanities. Key Features Offers a truly global approach by giving the current health status in each country of five continents Compares the mortality rates of infectious diseases and non-communicable diseases in developing and developed countries Presents a historical context for important changes and issues in global health and serves as a foundation of knowledge Examines how mental health and related conditions in developing countries are increasing toward the level in developed countries Ties the curriculum in related health disciplines from biology, to psychology, to psychopharmacology Provides a glossary of health definitions, extensive cross-references to related topics, and thorough bibliographic citations Key Themes · Children's Health Countries: Africa Countries: Americas Countries: Asia Countries: Europe Countries: Pacific Diseases, Cancers Diseases, Localized Diseases, Systemic Drugs and Drug Companies Health Sciences Men's Health Mental Health Organizations and Associations People Procedures and Therapies Research Society and Health Women's Health The Encyclopedia of Global Health is a useful reference for health professionals, as well as for general populations, making it a must-have resource for any library.

Transgenerational and Epigenetic Effects of Developmental Exposure to Atrazine on Medaka (Oryzias Latipes)

Transgenerational and Epigenetic Effects of Developmental Exposure to Atrazine on Medaka (Oryzias Latipes)
A Book

by Jacob Alexander Cleary

  • Publisher : Unknown Publisher
  • Release : 2018
  • Pages : 57
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
GET BOOK

"Exposure to environmental chemicals can cause epigenetic transgenerational inheritance of altered phenotypes. Chemicals such as the plasticizer bisphenol-A (BPA), the fungicidal vinclozolin, and the oral contraceptive component 17a-ethinylestradiol (EE2) induce epigenetic changes in various species. Each of these chemicals is an environmentally pervasive endocrine disrupting compound, as is the case with the abundantly used herbicide atrazine, whose endocrine disrupting mechanisms still remain unclear. Atrazine (ATZ) is presently one of the most abundantly used herbicides in the United States, and a common contaminant of natural water bodies and drinking waters in high-use areas. ATZ belongs to the triazine herbicides which specifically target photosynthetic tissues, yet ATZ can affect animal health. Fish exposed to ATZ and EE2 display dysregulation of reproductive processes, which include alterations to the hypothalamic-pituitary-gonadal (HPG) axis pathways. However, the potential for ATZ-induced transgenerational inheritance of reproductive dysfunction has not been investigated in fish. The transgenerational reproductive consequences of ATZ exposure have been explored in rats, but fish are among the species at greatest risk from ATZ exposure, therefore, I chose a model species to represent this environmentally relevant scenario. In the present study I analyzed the effects of ATZ and EE2 exposures during early development on transgenerational reproductive dysregulation in Japanese medaka (Oryzias latipes). F0 medaka were exposed to ATZ, EE2, and a solvent during the first twelve days of development with no exposure over the subsequent three generations. These early developmental exposures overlap with the critical windows of embryonic germ cell development, gonadogenesis, and sex determination when gonadal DNA methylation is being reprogrammed. Exposed males and females of the F0 treatment lineages were bred to produce the F1 generation, the F1 offspring were bred to produce the F2 generation, and the F2 offspring were bred to produce the F3 generation. Neither ATZ nor EE2 altered sperm parameters, gonadosomatic, or hepatosomatic indices in the treated F0 generation. However, the hepatosomatic index was reduced in F2 females derived from F0 fish treated with either ATZ or EE2. Hepatosomatic and gonadosomatic indices are ratios of liver and gonad weights to the total weight of the fish, which are cursory metrics for evaluating energetic and reproductive health. The fecundity of F0 and F2 fish was unaffected by exposure to ATZ or EE2; however, the fertilization rate was decreased among the F2 fish derived from the low ATZ and low EE2 treated F0 generation. Moreover, there were significant transgenerational differences in the expression of reproductive regulatory genes and genes required for DNA methylation. Genomic methylation patterns are catalyzed by DNA methyltransferase enzymes (dnmts) that regulate the heritable transcriptional activity of specific regions of DNA essential to development. Present results suggest that early life exposure to ATZ and EE2 cause no significant effects in the immediate generation, but that future generations of fish are at greater risk of reproductive dysfunction."--Abstract from author supplied metadata.

The yale law journal

The yale law journal
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1986
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
GET BOOK