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Epigenetics and Reproductive Health

Epigenetics and Reproductive Health
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2020-09-12
  • Pages : 444
  • ISBN : 0128197544
  • Language : En, Es, Fr & De
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Epigenetics and Reproductive Health, a new volume in the Translational Epigenetics series, provides a thorough overview and discussion of epigenetics in reproduction and implications for reproductive medicine. Twenty international researchers discuss epigenetic mechanisms operating during the formation of male and female gametes, fertilization and subsequent embryo and placental development, particularly in mammals and transgenerational epigenetic inheritance. This volume also addresses aberrant epigenetic changes influencing male and female infertility, pregnancy related disorders, and those potentially linked to therapeutic manipulations and assisted reproductive technologies. Emphasis is placed on identifying biomarkers for early detection of aberrant epigenetic mechanisms. Later chapters examine the possibility of correcting these epigenetic dysfunctions, as well as current challenges and next steps in research, enabling new translational discoveries and efforts towards developing therapeutics. Thoroughly examines the influence of aberrant epigenetics during gametogenesis and embryogenesis, affecting parents, gametes and embryos, offspring and future generations Explores health outcomes for reproductive senescence, endocrine disruption, testicular cancer, prostrate cancer, breast cancer, ovarian, cancer, endometrial cancer and cervical cancers Features chapter contributions from international researchers in the field

Weighing the Future

Weighing the Future
Race, Science, and Pregnancy Trials in the Postgenomic Era

by Natali Valdez

  • Publisher : Unknown Publisher
  • Release : 2021-12-08
  • Pages : 284
  • ISBN : 9780520380134
  • Language : En, Es, Fr & De
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Epigenetics is the study of heritable changes in gene expression and has been heralded as one of the most promising new fields of scientific inquiry. Current large-scale pregnancy studies draw on epigenetics to connect pregnant women's behavioral choices, like diet and exercise, to future health risks for unborn babies. As the first ethnography of its kind, Weighing the Future examines the sociopolitical implications of ongoing pregnancy trials in the United States and the United Kingdom, illuminating how processes of scientific knowledge production are linked to capitalism, surveillance, and environmental reproduction. The environments we imagine to shape our genes, bodies, and future health are tied to race, gender, and structures of inequality. This groundbreaking book makes the case that science, and how we translate it, is a reproductive project that requires feminist vigilance. Instead of fixating on a future at risk, this book brings attention to the present at stake.

Reproductive Medicine for Clinical Practice

Reproductive Medicine for Clinical Practice
Medical and Surgical Aspects

by Joseph G. Schenker,John J. Sciarra,Liselotte Mettler,Andrea R. Genazzani,Martin Birkhaeuser

  • Publisher : Springer
  • Release : 2018-09-29
  • Pages : 234
  • ISBN : 3319780093
  • Language : En, Es, Fr & De
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This first volume of the series of the International Academy of Human Reproduction focuses on new aspects of reproductive medicine, from the professional responsibility model of ethics to the areas of high clinical involvement in human reproduction, such as endometriosis, polycystic ovary, family planning and post-coital contraception. The book discusses fertility and assisted reproductive techniques in the context of genetics and epigenetics as well as psychosomatic and longevity aspects. In addition, it presents new technologies and therapeutic strategies to improve IVF results and prevent ovarian hyperstimulation syndrome, as well the new challenges and the future of imaging in reproduction. Menopause and the effects of estrogens on atero-prevention, mood, and more generally the reproductive hormones impact on dementia and healthy aging are also covered. Further, it includes a section devoted to innovative aspects of gynecological surgery, discussing the treatments of vaginal aplasia, reproductive microsurgery and technological breakthroughs in pelvic organ prolapse surgery. Last, but not least, it examines the syndromic aspects of preterm birth. This volume is a useful and comprehensive tool for gynecologists, obstetricians, endocrinologists and all specialists who deal with women’s reproductive health.

Bisphenols and Male Reproductive Health

Bisphenols and Male Reproductive Health
A Book

by Arcangelo Barbonetti,Nicola Bernabò,Settimio D’Andrea,David H. Volle

  • Publisher : Frontiers Media SA
  • Release : 2020-12-10
  • Pages : 129
  • ISBN : 2889662039
  • Language : En, Es, Fr & De
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Animal Models and Human Reproduction

Animal Models and Human Reproduction
A Book

by Heide Schatten,Gheorghe M. Constantinescu

  • Publisher : John Wiley & Sons
  • Release : 2017-01-12
  • Pages : 600
  • ISBN : 1118881427
  • Language : En, Es, Fr & De
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Our knowledge of reproductive biology has increased enormously in recent years on cellular, molecular, and genetic levels, leading to significant breakthroughs that have directly benefitted in vitro fertilization (IVF) and other assisted reproductive technologies (ART) in humans and animal systems. Animal Models and Human Reproduction presents a comprehensive reference that reflects the latest scientific research being done in human reproductive biology utilizing domestic animal models. Chapters on canine, equine, cow, pig, frog, and mouse models of reproduction reflect frontier research in placental biology, ovarian function and fertility, non-coding RNAs in gametogenesis, oocyte and embryo metabolism, fertilization, cryopreservation, signal transduction pathways, chromatin dynamics, epigenetics, reproductive aging, and inflammation. Chapters on non-human primate models also highlight recent advancements into such issues as human in vitro fertilization (IVF) and assisted reproductive technologies (ART). This book offers animal scientists, reproductive biology scientists, clinicians and practitioners, invaluable insights into a wide range of issues at the forefront of human reproductive health.

Male Reproductive Health

Male Reproductive Health
A Book

by Wei Wu,Francesco Ziglioli,Umberto Maestroni

  • Publisher : BoD – Books on Demand
  • Release : 2020-03-04
  • Pages : 202
  • ISBN : 1789856477
  • Language : En, Es, Fr & De
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Male reproductive health is an important area affecting men's overall health and well-being. Infertility is a worldwide problem that affects approximately 15% of married couples. Half of these cases can be traced to male partners. Infertile men are at an elevated risk of cancer development later in life, primarily genitourinary malignancies such as testicular and prostate cancer. This book will focus on male reproductive health, from the aspects of semen quality, male infertility, testicular cancer, and prostate cancer, and their detection, diagnosis, treatment, and prevention.

Environmental Impacts on Reproductive Health and Fertility

Environmental Impacts on Reproductive Health and Fertility
A Book

by Tracey J. Woodruff,Sarah J. Janssen,Louis J. Guillette, Jr,Linda C. Giudice

  • Publisher : Cambridge University Press
  • Release : 2010-01-28
  • Pages : 129
  • ISBN : 1139484842
  • Language : En, Es, Fr & De
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Many reproductive and developmental health problems are caused by exposure to chemicals that are widely dispersed in our environment. These problems include infertility, miscarriage, poor pregnancy outcomes, abnormal fetal development, early puberty, endometriosis, and diseases and cancers of reproductive organs. The compelling nature of the collective science has resulted in recognition of a new field of environmental reproductive health. Focusing on exposures to environmental contaminants, particularly during critical periods in development and their potential effects on all aspects of future reproductive life-course, this book provides the first comprehensive source of information bringing together the arguments that are spread out among various scientific disciplines in environmental health, clinical and public health fields. It provides a review of the science in key areas of the relationship between environmental contaminants and reproductive health outcomes, and recommendations on efforts toward prevention in clinical care and public policy.

Epigenetics and Human Reproduction

Epigenetics and Human Reproduction
A Book

by Sophie Rousseaux,Saadi Khochbin

  • Publisher : Springer Science & Business Media
  • Release : 2010-11-03
  • Pages : 372
  • ISBN : 9783642147739
  • Language : En, Es, Fr & De
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Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the ‘Epigenetics and Human Health’ series discusses the role of epigenetics in human reproduction

Genetic and Epigenetic Aspects of Assisted Reproductive Technologies

Genetic and Epigenetic Aspects of Assisted Reproductive Technologies
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 99
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Handbook of Fertility

Handbook of Fertility
Nutrition, Diet, Lifestyle and Reproductive Health

by Ronald Ross Watson

  • Publisher : Academic Press
  • Release : 2015-04-27
  • Pages : 452
  • ISBN : 0128009934
  • Language : En, Es, Fr & De
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Handbook of Fertility: Nutrition, Diet, Lifestyle and Reproductive Health focuses on the ways in which food, dietary supplements, and toxic agents, including alcohol and nicotine affect the reproductive health of both women and men. Researchers in nutrition, diet, epidemiology, and endocrinology will find this comprehensive resource invaluable in their long-term goal of understanding and improving reproductive health. This book brings together a broad range of experts researching the different aspects of foods and dietary supplements that promote or detract from reproductive health. Section One contains several overview chapters on fertility, how it is assessed, and how it can be affected by different metabolic states, nutritional habits, dietary supplements, the action of antioxidants, and lifestyle choices. Sections Two and Three consider how male and female fertility are affected by obesity, metabolic syndrome, hormonal imbalance, and even bariatric surgery. Section Four explores the ways diet, nutrition, and lifestyle support or retard the success of in vitro fertilization, while Section Five explores how alcohol and other drugs of abuse lower fertility in both women and men. Explores how alcohol, nicotine, and other drugs of abuse disrupt and impair reproductive health Reviews studies of common conditions such as obesity and metabolic syndrome and their effect on fertility and reproductive health Investigates the components of foods and dietary supplements, in particular oxidative stress and antioxidants Presents the nutritional effects of foods and dietary supplements and their benefits and risks relating to reproductive health

Human Reproductive and Prenatal Genetics

Human Reproductive and Prenatal Genetics
A Book

by Peter C. K. Leung,Jie Qiao

  • Publisher : Academic Press
  • Release : 2018-08-28
  • Pages : 709
  • ISBN : 0128135719
  • Language : En, Es, Fr & De
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Human Reproductive and Prenatal Genetics presents the latest material from a detailed molecular, cellular and translational perspective. Considering its timeliness and potential international impact, this all-inclusive and authoritative work is ideal for researchers, students, and clinicians worldwide. Currently, there are no comprehensive books covering the field of human reproductive and prenatal genetics. As such, this book aims to be among the largest and most useful references available. Features chapter contributions from leading international scientists and clinicians Provides in-depth coverage of key topics in human reproductive and prenatal genetics, including genetic controls, fertilization and implantation, in vitro culture of the human embryo for the study of post-implantation development, and more Identifies how researchers and clinicians can implement the latest genetic, epigenetic, and –omics based approaches

The Zero Trimester

The Zero Trimester
Pre-Pregnancy Care and the Politics of Reproductive Risk

by Miranda Waggoner

  • Publisher : Univ of California Press
  • Release : 2017-09-12
  • Pages : 280
  • ISBN : 0520288076
  • Language : En, Es, Fr & De
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-A healthy pregnancy is now defined well before pregnancy even begins. Public health messages promote pre-pregnancy health and health care by encouraging reproductive-age women to think of themselves as mothers before they think of themselves as women. This happens despite little evidence that such an approach improves maternal and child health. This book examines the dramatic shift in ideas about reproductive risk and birth outcomes over the last several decades, unearthing how these ideas intersect with the politics of women's health and motherhood at the beginning of the twenty-first century.---Provided by publisher.

Human Reproductive Genetics

Human Reproductive Genetics
Emerging Technologies and Clinical Applications

by Juan A. Garcia-Velasco,Emre Seli

  • Publisher : Academic Press
  • Release : 2020-04-19
  • Pages : 340
  • ISBN : 0128167491
  • Language : En, Es, Fr & De
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Human Reproductive Genetics: Emerging Technologies and Clinical Applications presents a great reference for clinicians and researchers in reproductive medicine. Part I includes a brief background of genetics and epigenetics, probability of disease, and the different techniques that are being used today for analysis and genetic counseling. Part II focuses on the analysis of the embryo, current controversies and future concepts. Part III comprises different clinical scenarios that clinicians frequently face in practice. The increasing amount of genetic tests available and the growing information that patients handle makes this section a relevant part of the fertility treatment discussion. Finally, Part IV concludes with the psychological aspects of genetic counseling and the role of counselor and bioethics in human reproduction. Provides an essential reference for clinicians involved in reproductive medicine Builds foundational knowledge on new genetic tests coming into the clinical scenario for physicians involved with patients Assembles critically evaluated chapters that cover basic concepts of genetics and epigenetics and the techniques involved, including preimplantation genetic testing, controversies, and more

Epigenetics In Human Reproduction And Development

Epigenetics In Human Reproduction And Development
A Book

by Naumova Anna K,Taketo-hosotani Teruko

  • Publisher : World Scientific
  • Release : 2016-12-20
  • Pages : 304
  • ISBN : 9813144289
  • Language : En, Es, Fr & De
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Epigenetics is defined as heritable changes that do not affect the DNA sequence but influence gene expression. Epigenetic changes occur at the levels of DNA, histone, protein, and chromatin structures. Proper epigenetic modifications are essential for cell differentiation and function during development, while some epigenetic modifications are passed on from parents to offspring through gametes. Therefore, alterations of epigenetic states would have serious consequences for human development and health. This realization and the advent of new technologies have encouraged the advance of epigenetic studies in recent years. Nonetheless, many aspects of epigenetics, such as regulatory mechanisms and evolutional advantages, remain to be better understood. Written by 26 scientists at the forefront of epigenetics research, this book discusses the different facets of epigenetics: from gametogenesis to child development, as well as from mechanistic studies in animal models to reviews of human clinical data.

Encyclopedia of Reproduction

Encyclopedia of Reproduction
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2018-06-29
  • Pages : 3868
  • ISBN : 0128151455
  • Language : En, Es, Fr & De
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Encyclopedia of Reproduction, Second Edition comprehensively reviews biology and abnormalities, also covering the most common diseases in humans, such as prostate and breast cancer, as well as normal developmental biology, including embryogenesis, gestation, birth and puberty. Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers, from advanced undergraduate students, to research professionals. Chapters also explore the latest advances in cloning, stem cells, endocrinology, clinical reproductive medicine and genomics. As reproductive health is a fundamental component of an individual’s overall health status and a central determinant of quality of life, this book provides the most extensive and authoritative reference within the field. Provides a one-stop shop for information on reproduction that is not available elsewhere Includes extensive coverage of the full range of topics, from basic, to clinical considerations, including evolutionary advances in molecular, cellular, developmental and clinical sciences Includes multimedia and interactive teaching tools, such as downloadable PowerPoint slides, video content and interactive elements, such as the Virtual Microscope

Folate Deficiency in Utero and Postnatally Impairs Spermatogenesis, Fertility, Epigenetic Programming and Offspring Health in a Mouse Model

Folate Deficiency in Utero and Postnatally Impairs Spermatogenesis, Fertility, Epigenetic Programming and Offspring Health in a Mouse Model
A Book

by Chen Xu

  • Publisher : Unknown Publisher
  • Release : 2010
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Epigenetics and Human Reproduction

Epigenetics and Human Reproduction
A Book

by Sophie Rousseaux,Saadi Khochbin

  • Publisher : Springer
  • Release : 2011-07-23
  • Pages : 372
  • ISBN : 9783642147746
  • Language : En, Es, Fr & De
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Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the ‘Epigenetics and Human Health’ series discusses the role of epigenetics in human reproduction

Transgenerational and Epigenetic Effects of Developmental Exposure to Atrazine on Medaka (Oryzias Latipes)

Transgenerational and Epigenetic Effects of Developmental Exposure to Atrazine on Medaka (Oryzias Latipes)
A Book

by Jacob Alexander Cleary

  • Publisher : Unknown Publisher
  • Release : 2018
  • Pages : 57
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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"Exposure to environmental chemicals can cause epigenetic transgenerational inheritance of altered phenotypes. Chemicals such as the plasticizer bisphenol-A (BPA), the fungicidal vinclozolin, and the oral contraceptive component 17a-ethinylestradiol (EE2) induce epigenetic changes in various species. Each of these chemicals is an environmentally pervasive endocrine disrupting compound, as is the case with the abundantly used herbicide atrazine, whose endocrine disrupting mechanisms still remain unclear. Atrazine (ATZ) is presently one of the most abundantly used herbicides in the United States, and a common contaminant of natural water bodies and drinking waters in high-use areas. ATZ belongs to the triazine herbicides which specifically target photosynthetic tissues, yet ATZ can affect animal health. Fish exposed to ATZ and EE2 display dysregulation of reproductive processes, which include alterations to the hypothalamic-pituitary-gonadal (HPG) axis pathways. However, the potential for ATZ-induced transgenerational inheritance of reproductive dysfunction has not been investigated in fish. The transgenerational reproductive consequences of ATZ exposure have been explored in rats, but fish are among the species at greatest risk from ATZ exposure, therefore, I chose a model species to represent this environmentally relevant scenario. In the present study I analyzed the effects of ATZ and EE2 exposures during early development on transgenerational reproductive dysregulation in Japanese medaka (Oryzias latipes). F0 medaka were exposed to ATZ, EE2, and a solvent during the first twelve days of development with no exposure over the subsequent three generations. These early developmental exposures overlap with the critical windows of embryonic germ cell development, gonadogenesis, and sex determination when gonadal DNA methylation is being reprogrammed. Exposed males and females of the F0 treatment lineages were bred to produce the F1 generation, the F1 offspring were bred to produce the F2 generation, and the F2 offspring were bred to produce the F3 generation. Neither ATZ nor EE2 altered sperm parameters, gonadosomatic, or hepatosomatic indices in the treated F0 generation. However, the hepatosomatic index was reduced in F2 females derived from F0 fish treated with either ATZ or EE2. Hepatosomatic and gonadosomatic indices are ratios of liver and gonad weights to the total weight of the fish, which are cursory metrics for evaluating energetic and reproductive health. The fecundity of F0 and F2 fish was unaffected by exposure to ATZ or EE2; however, the fertilization rate was decreased among the F2 fish derived from the low ATZ and low EE2 treated F0 generation. Moreover, there were significant transgenerational differences in the expression of reproductive regulatory genes and genes required for DNA methylation. Genomic methylation patterns are catalyzed by DNA methyltransferase enzymes (dnmts) that regulate the heritable transcriptional activity of specific regions of DNA essential to development. Present results suggest that early life exposure to ATZ and EE2 cause no significant effects in the immediate generation, but that future generations of fish are at greater risk of reproductive dysfunction."--Abstract from author supplied metadata.

Epigenetics in Society

Epigenetics in Society

by Windsor Epigenetics Study Group

  • Publisher : University of Windsor
  • Release : 2015-10-26
  • Pages : 327
  • ISBN : 0920233724
  • Language : En, Es, Fr & De
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This is a book written by students of diverse disciplines, and intended for students and educated lay people. We intend this book to serve several functions. First, we want to make the field of epigenetics accessible to lay readers. Second, and more importantly, we want to excite further interest and concern regarding the social, ethical, legal, health, and policy implications that this field will have for all arenas of our lives. Third, we want to arm our readers with knowledge and wariness so that they can understand and critique the nuanced debates that will inevitably arise when costs and benefits must be weighed: while the effects of epigenetics upon us as individuals may be subtle, the demographic implications and costs are huge.

Proceedings of 2nd International Congress on Epigenetics & Chromatin 2017

Proceedings of 2nd International Congress on Epigenetics & Chromatin 2017
Journal of Clinical Epigenetics : Volume 3

by ConferenceSeries

  • Publisher : ConferenceSeries
  • Release : 2021
  • Pages : 113
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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November 06-08, 2017 Frankfurt, Germany Key Topics : Epigenetics, Epigenomics, Immunogenetics, Translational Epigenetics, Neurodevelopmental Disorders, Bioinformatics Development in Epigenetics, Epigenetics and Environmental Origins of Cancer, Epigenetic Diseases – Clinical Applications, Pharmacogenomics & Personalized Medicine, Genetic Disorders, Current Case studies/ Discussions: Epigenetics, Cancer Epigenetics, Epigenetics Inheritance, Epigenetic Regulation, Epigenetics Mechanism, Epigenetics Psychology, Epigenetics Factors, Epigenetics Therapy, Clinical Epigenetics, Epigenetics Markers, Epigenetics Methylation, Epigenetics Silencing, Epigenetics Alteration, Neuronal Epigenetics, Epigenetics and Nutrition, Reproductive Epigenetics, Animal Epigenetics, Plant Epigenetics, Medical Epigenetics,