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Forensic Practitioner's Guide to the Interpretation of Complex DNA Profiles

Forensic Practitioner's Guide to the Interpretation of Complex DNA Profiles
A Book

by Peter Gill,Øyvind Bleka,Oskar Hansson,Corina Benschop,Hinda Haned

  • Publisher : Academic Press
  • Release : 2020-06-10
  • Pages : 530
  • ISBN : 0128205687
  • Language : En, Es, Fr & De
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Over the past twenty years, there’s been a gradual shift in the way forensic scientists approach the evaluation of DNA profiling evidence that is taken to court. Many laboratories are now adopting ‘probabilistic genotyping’ to interpret complex DNA mixtures. However, current practice is very diverse, where a whole range of technologies are used to interpret DNA profiles and the software approaches advocated are commonly used throughout the world. Forensic Practitioner’s Guide to the Interpretation of Complex DNA Profiles places the main concepts of DNA profiling into context and fills a niche that is unoccupied in current literature. The book begins with an introduction to basic forensic genetics, covering a brief historical description of the development and harmonization of STR markers and national DNA databases. The laws of statistics are described, along with the likelihood ratio based on Hardy-Weinberg equilibrium and alternative models considering sub-structuring and relatedness. The historical development of low template mixture analysis, theory and practice, is also described, so the reader has a full understanding of rationale and progression. Evaluation of evidence and statement writing is described in detail, along with common pitfalls and their avoidance. The authors have been at the forefront of the revolution, having made substantial contributions to theory and practice over the past two decades. All methods described are open-source and freely available, supported by sets of test-data and links to web-sites with further information. This book is written primarily for the biologist with little or no statistical training. However, sufficient information will also be provided for the experienced statistician. Consequently, the book appeals to a diverse audience Covers short tandem repeat (STR) analysis, including database searching and massive parallel sequencing (both STRs and SNPs) Encourages dissemination and understanding of probabilistic genotyping by including practical examples of varying complexity Written by authors intimately involved with software development, training at international workshops and reporting cases worldwide using the methods described in this book

Advanced Topics in Forensic DNA Typing: Interpretation

Advanced Topics in Forensic DNA Typing: Interpretation
A Book

by John M. Butler

  • Publisher : Academic Press
  • Release : 2014-07-28
  • Pages : 608
  • ISBN : 012405854X
  • Language : En, Es, Fr & De
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Advanced Topics in Forensic DNA Typing: Interpretation builds upon the previous two editions of John Butler’s internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience. Intended as a third-edition companion to the Fundamentals of Forensic DNA Typing volume published in 2010 and Advanced Topics in Forensic DNA Typing: Methodology published in 2012, this book contains 16 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field. Over 80 % of the content of this book is new compared to previous editions. Provides forensic DNA analysts coverage of the crucial topic of DNA mixture interpretation and statistical analysis of DNA evidence Worked mixture examples illustrate the impact of different statistical approaches for reporting results Includes allele frequencies for 24 commonly used autosomal STR loci, the revised Quality Assurance Standards which went into effect September 2011

Expert Evidence

Expert Evidence
A Practitioner's Guide to Law, Science, and the FJC Manual

by Bert Black,Patrick W. Lee

  • Publisher : West Group Publishing
  • Release : 1997
  • Pages : 637
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Advances in Genetic Information

Advances in Genetic Information
A Guide for State Policy Makers : Employment Issues, Insurance, Criminal Justice, Health Care, Genetic Testing, Civil Liberties

by R. Steven Brown,Karen Marshall

  • Publisher : Council of State Government
  • Release : 1993
  • Pages : 123
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Current Law Index

Current Law Index
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2006
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Advances in Human Palaeopathology

Advances in Human Palaeopathology
A Book

by Ron Pinhasi,Simon Mays

  • Publisher : John Wiley & Sons
  • Release : 2008-02-28
  • Pages : 408
  • ISBN : 047072417X
  • Language : En, Es, Fr & De
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This volume presents a truly integrated methodological and biocultural approach to the expanding discipline of human palaeopathology. The book provides researchers and practitioners with a comprehensive guide to the main methods and techniques that are currently available for studying diseases and related conditions from human skeletal remains. It also describes the ways in which these methods can be applied to the reconstruction of health and disease in the past. The first part of the book deals with the survival of palaeopathological evidence and provides an up-to-date account of some of the latest techniques for studying disease in ancient remains. These include imaging techniques, such as radiography and CT scanning, and biochemical and histological analyses. Part two discusses the diagnosis and interpretation of particular classes of disease. The emphasis here is on what can be learnt by taking a biocultural or holistic approach to the study of disease frequencies at a population level. Combines theoretical, methodological and diagnostic aspects with key biocultural approaches. Includes overviews of the latest applicable techniques from molecular biology, biochemistry, histopathology and medical imaging. Written by an international team of experts. This book is an invaluable resource for biological anthropologists and archaeologists who study health and disease in past populations. It is also of interest to medical researchers dealing with epidemiological, diagnostic and pathophysiological aspects of diseases, who need a perspective upon the ways in which particular diseases affected earlier generations. Praise from the reviews: “... This book offers an impressive amount of information for both students and more advanced researchers. Its value lies in the vast expertise the contributors have to offer, with all of them being experts with long-standing careers in their respective fields, as well as the geographical distribution of examples that are given to illustrate specific diseases... outstanding and it truly is an important resource for anyone interested in palaeopathology.” PALEOPATHOLOGY NEWSLETTER “The strengths of the book are numerous, but I am especially impressed with the clarity of presentation... I strongly recommend the book, and plan on using it in my classes as assigned reading to emphasize the very complex nature of diagnosis and its essential role of providing baseline information for interpreting health profiles of ancient populations.” THE QUARTERLY REVIEW OF BIOLOGY “It may be asked if we really need yet another book on paleopathology, especially because there are many acclaimed sources available. In this case, the answer must be a resounding ‘‘Yes!’’...Visually and textually, this volume is of exceptional value for guiding future generations of paleopathologists.” AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY "Pinhasi and Mays have produced an excellent, balanced compilation that reflects what is currently happening in paleopathology research and that nicely addresses paleopathology as both discipline and tool, highlighting technical advanced and schooling us on how disease manifests in the human skeleton. This is valuable resource that students and professionals interested in human paloepathology should consider adding to their libraries." AMERICAN JOURNAL OF HUMAN BIOLOGY

Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2011 Edition

Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2011 Edition
A Book

by Anonim

  • Publisher : ScholarlyEditions
  • Release : 2012-01-09
  • Pages : 4229
  • ISBN : 1464963444
  • Language : En, Es, Fr & De
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Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Pharmacology, Pharmacy, Drug Research, and Drug Innovation. The editors have built Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Pharmacology, Pharmacy, Drug Research, and Drug Innovation in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition

Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition
A Book

by Anonim

  • Publisher : ScholarlyEditions
  • Release : 2012-01-09
  • Pages : 3453
  • ISBN : 1464963509
  • Language : En, Es, Fr & De
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Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Discovery, Experimental, and Laboratory Medicine. The editors have built Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Discovery, Experimental, and Laboratory Medicine in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.