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Gap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development including cell differentiation, cell migration and survival, and tissue homeostasis, as well as in human diseases including hearing loss, neuropathies, epilepsy, brain trauma, and cardiovascular disease. This volume provides neuroscience researchers and students with a single source for information covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain. In addition, the book also discusses human disease conditions associated with mutations in single gap junction connexion genes, making it applicable to clinicians doing translational research. Finally, it includes reviews of pharmacological studies with gap junction blockers and openers, summarizing information obtained from phenotyping gap junctions mouse mutants. Serves as the most current and comprehensive reference available covering the physiological, behavioral and pathophysiological roles of gap junctions in the brain Chapters summarize knowledge of the basic physiology of gap junctions in the brain, as well as of human disease conditions associated with mutations in single gap junction connexin genes Includes reviews of pharmacological studies with gap junction blockers and openers, summarizing information obtained from phenotyping gap junctions mouse mutants

Gap junctions are present in nearly all tissues, regardless of their embronic origin and have long been of great interest to scientists from many different disciplines. The international meeting on which this book is based brought together 157 scientists from 12 countries and almost as many scientific disciplines. The papers presented at the meeting were reviewed and updated prior to publication in this book. The seven parts of the book progress from general topics to the more specific ones (role of gap junctions in various tissues, regulation and biochemistry, and cancer).

This volume focuses on the biological meaning of intercellular communication through gap junctions in various organs. The most recent up-to-date findings have been included.

This book is a conceptually driven and accessible introduction to behavioral neuroscience. Focused, concise and coherent, it reflects integrative trends in the field while making human neuroscience accessible to a wider student audience. Conceptually driven and concise. The field of biological psychology and behavioral neuroscience has grown exponentially in the past decade, and most textbooks have responded by becoming bloated tomes that drown students in unnecessary factoids. Beatty provides just the essentials necessary in a text that is focused, concise, and coherent. A contemporary integrative approach with an emphasis on behavior. Some books in this market focus more on biological mechanisms at the expense of how the biology t

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