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Genetics of Bone Biology and Skeletal Disease

Genetics of Bone Biology and Skeletal Disease
A Book

by Rajesh V. Thakker,Michael P. Whyte,John Eisman,Takashi Igarashi

  • Publisher : Academic Press
  • Release : 2017-10-31
  • Pages : 878
  • ISBN : 0128041986
  • Language : En, Es, Fr & De
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Genetics of Bone Biology and Skeletal Disease, Second Edition, is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid and related disorders, and vitamin D and renal disorders. The first section is specifically devoted to providing an overview of bone biology and structure, joint and cartilage biology, principles of endocrine regulation of bone, and the role of neuronal regulation and energy homeostasis. The second section reviews the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, copy number variation, prospects of gene therapy, pharmacogenomics, genetic testing and counseling, as well as the generation and utilizing of mouse models. The third section details advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasias, and rarer bone disorders. The fourth section highlights the central role of the parathyroids in calcium and skeletal homeostasis by reviewing the molecular genetics of: hyperparathyroidism, hypoparathyrodism, endocrine neoplasias, and disorders of the PTH and calcium-sensing receptors. The fifth section details molecular and cellular advances across associated renal disorders such as vitamin D and rickets. Identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluation of treatments Demonstrates how the interactions between bone and joint biology, physiology, and genetics have greatly enhanced the understanding of normal bone function as well as the molecular pathogenesis of metabolic bone disorders Summarizes the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder

Principles of Bone Biology

Principles of Bone Biology
A Book

by John P. Bilezikian,T. John Martin,Thomas L. Clemens,Clifford Rosen

  • Publisher : Academic Press
  • Release : 2019-08-22
  • Pages : 2024
  • ISBN : 012814842X
  • Language : En, Es, Fr & De
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Preface from the first edition (1996): "The world of modern science is undergoing a number of spectacular events that are redefining our understanding of ourselves. As with any revolution, we should take stock of where we have been, where we are, and where we are going. Our special world of bone biology is participating in and taking advantage of the larger global revolution in modern science... we assembled experts from all over the world and asked them to focus on the current state of knowledge and the prospects for new knowledge in their area of expertise. To this end, Principles of Bone Biology was conceived." - John P. Bilezikian, Lawrence G. Raisz, Gideon A. Rodan Praise for the previous edition: "Students, teachers, and practitioners will benefit from reading it, and investigators will use it as a reference work; it will certainly be consulted frequently." --The New England Journal of Medicine For over two decades, "Big Gray" has been the go-to repository of knowledge in the disciplines related to bone and mineral metabolism. The fourth edition is a must-have for students new to the field; young investigators at the graduate or postgraduate level beginning their research careers; established scientists who need to keep up with the changing nature of the field, looking to enrich their own research programs, or who are changing their career direction; clinicians who want ready access to up-to-date relevant basic science. This new edition builds on the successful formula from previous editions, taking the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics. Principles of Bone Biology, Fourth Edition provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. Bone research continues to generate enormous attention, due to the broad public health implications of osteoporosis and related bone disorders. This classic, fully updated, two volume reference is designed for anyone involved in the study of bone biology. Provides a "one-stop" shopping paradise. Anything you want to find about bone biology is here and written by the world’s experts THE essential resource for anyone involved in the study of the skeleton and metabolic bone diseases Covers everything from the basic scientific concepts to the underlying principles of therapeutics and management Allows readers to easily search and locate information quickly in the online format Volumes include: Basic Principles; Molecular Mechanisms of Metabolic Bone Disease; Pharmacological Mechanisms of Therapeutics; Methods in Bone Research

The Genetics of Osteoporosis and Metabolic Bone Disease

The Genetics of Osteoporosis and Metabolic Bone Disease
A Book

by Michael J. Econs

  • Publisher : Springer Science & Business Media
  • Release : 2000-05-12
  • Pages : 462
  • ISBN : 1592590330
  • Language : En, Es, Fr & De
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The explosive growth in the field of molecular biology over the last two decades has started to make a great impact on clinical medicine. Genes have been cloned for diseases that were poorly understood only a decade ago. Additionally, investigators are increasingly aware that there are strong genetic components to complex disorders, such as osteoporosis, that are not classically thought of as genetic disorders. New insights into the pathogenesis of metabolic bone diseases have been obtained from investigations into the molecular biology of these diseases and new therapies will become available based on these new insights. In The Genefies of Osteoporosis and Metabolie Bane Disease, I have assembled an internationally renowned group of experts to write the various chapters. Each of the authors is an expert in his/her field who is currently performing research on the content of their chapter and have made important contributions to the understanding of the clinical fea tures and pathophysiology of metabolic bone disease and genetics. The first part of The Genefies of Osteoporosis and Metabolie Bane Disease addresses issues related to genetic contributions to the development of osteoporosis and the many factors that must be considered when searching for genesthat predispose to osteoporosis. The second sec tion addresses recent advances in the clinical and molecular biological aspects of inherited metabolic bone disorders. The last section reviews the latest techniques for finding genes that predispose to metabolic bone diseases.

Diabetes and Endocrine

Diabetes and Endocrine
Key Articles from the Medicine journal

by Derek G. Waller

  • Publisher : Elsevier Health Sciences
  • Release : 2016-09-13
  • Pages : 129
  • ISBN : 0702071234
  • Language : En, Es, Fr & De
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Diabetes & Endocrine is a new e-book in a collection of subject-themed e-books containing relevant key articles from Medicine. The e-books provide a perfect source of revision for post-graduate exams in clinical medicine and portfolio material for life-long learning. As well as mapping to the UK Core Medical Training curriculum, these e-books also enable anyone with a short-term interest in a specific area to buy individual articles at a price-point that will give affordable access to all readers (from medical students to GPs and practitioners in related areas). The quality of user experience on mobiles, tablets and laptops will be an added bonus for learning on the move. The whole board has been involved in the creation of this content and are therefore listed as authors on all the e-books. In addition we extend our warm thanks for their contribution to these e-books to the past Chairman Allister Vale (who stepped down from the board in 2015) and to John Mucklow, who stepped down in 2016. Derek Waller, on behalf of the Editorial Board About the journal The parent journal (www.medicinejournal.co.uk) is a rolling, continuously updated review of clinical medicine over a 4-year cycle covering all the important topics for core medical training. Its Editorial Board comprises some of Europe’s most influential specialists. The journal’s articles are refreshed, updated, augmented or replaced as appropriate each time the subject is due for revision to provide a concise overview of knowledge and practice core to the curriculum. Each article is written by invited experts and overseen by the relevant subject specialist on the Board. A trainee representative on the Board ensures relevance and accessibility for exam candidates. About the Medicine journal e-books Diabetes & Endocrine is a new e-book in a collection of subject-themed e-books containing relevant key articles from Medicine. The e-books provide a perfect source of revision for post-graduate exams in clinical medicine and portfolio material for life-long learning. As well as mapping to the UK Core Medical Training curriculum, these e-books also enable anyone with a short-term interest in a specific area to buy individual articles at a price-point that will give affordable access to all readers (from medical students to GPs and practitioners in related areas). The quality of user experience on mobiles, tablets and laptops will be an added bonus for learning on the move. The whole board has been involved in the creation of this content and are therefore listed as authors on all the e-books. In addition we extend our warm thanks for their contribution to these e-books to the past Chairman Allister Vale (who stepped down from the board in 2015) and to John Mucklow, who stepped down in 2016. Derek Waller, on behalf of the Editorial Board About the journal The parent journal (www.medicinejournal.co.uk) is a rolling, continuously updated review of clinical medicine over a 4-year cycle covering all the important topics for core medical training. Its Editorial Board comprises some of Europe’s most influential specialists. The journal’s articles are refreshed, updated, augmented or replaced as appropriate each time the subject is due for revision to provide a concise overview of knowledge and practice core to the curriculum. Each article is written by invited experts and overseen by the relevant subject specialist on the Board. A trainee representative on the Board ensures relevance and accessibility for exam candidates.

Current Topics in Bone Biology

Current Topics in Bone Biology
A Book

by Hong-wen Deng,Yao-zhong Liu

  • Publisher : World Scientific
  • Release : 2005
  • Pages : 528
  • ISBN : 9812701176
  • Language : En, Es, Fr & De
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This book covers a wide spectrum of areas related to basic bone research. While bone remodeling, bone development, and osteoclast biology constitute the main contents, topics important to the understanding of bone metabolism and treatment of bone-related diseases are also intensively reviewed. Three chapters are dedicated to the classic topic of bone mechanics, which include a brief overview of the mechanostat hypothesis, a more detailed review on mechanotransduction and bone adaptation, and a chapter illustrating the basic principles of bone mechanical testing. New emerging fields such as skeletal stem cells, bone tissue engineering, phytoestrogens applications, and bone genetics study using mouse models, are also covered in detail. The book closes with a special chapter dedicated to state-of-the-art advances in bone biology research.

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism
A Book

by Anonim

  • Publisher : John Wiley & Sons
  • Release : 2018-09-25
  • Pages : 1136
  • ISBN : 1119266572
  • Language : En, Es, Fr & De
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The authoritative reference to bone diseases and disorders of mineral metabolism, revised and updated Now in its ninth edition, The Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism offers an updated and comprehensive guide to bone and mineral health. Since it was first published 30 years ago, the Primer has become the leading reference on the topic. With contributions from noted experts, the text explores basic biological factors of healthy development and disease states and makes the information accessible for clinical interventions. The ninth edition provides concise coverage of the widest possible spectrum of metabolic bone diseases and disorders of mineral metabolism. The new edition of this invaluable reference expands coverage and includes the most recent developments in the field that help to strengthen its usefulness and ensure that the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism maintains its place as the pre-eminent reference on bone and mineral health. This vital resource: Provides the most accurate, up-to-date evidence-based information on basic and clinical bone science Includes more than 10 new chapters and contributions from 300 authors from wide-ranging international research centers Captures the very cutting edge of research covering mineral homeostasis, osteoporosis and other metabolic bone diseases, skeletal measurement technologies, and genetics Presents a new companion website with useful supplementary materials at www.asbmrprimer.com Written for advanced students, clinicians, and researchers working in the field of bone health and disease, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism is the definitive, one-stop reference for anyone working in the field of bone health and disease.

Basic and Applied Bone Biology

Basic and Applied Bone Biology
A Book

by David B. Burr,Matthew R. Allen

  • Publisher : Academic Press
  • Release : 2019-02-20
  • Pages : 478
  • ISBN : 0128132604
  • Language : En, Es, Fr & De
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Basic and Applied Bone Biology, Second Edition, provides an overview of skeletal biology, from the molecular level, to the organ level, including cellular control, interaction and response, adaptive responses to various external stimuli, and the interaction of the skeletal system with other metabolic processes in the body. The book includes chapters that address how the skeleton can be evaluated through the use of various imaging technologies, biomechanical testing, histomorphometric analysis, and the use of genetically-modified animal models. Each chapter delves deep into the important details of topics covered to provide a solid understanding of the basics of bone biology. Bone biology researchers who also train undergraduate and graduate students in the lab will use this book constantly to orient new students on the basics of the field and as a background reference for many of the technical aspects of qualification in bone biology (e.g., mechanics, histomorphometry, genetic modification, biochemistry, etc.). Presents an in-depth overview of skeletal biology, from molecular to organ level Offers refresher level content for clinicians or researchers outside their areas of expertise Includes updated and complete references Incorporates expanded study questions at the end of each chapter for further exploration Covers topics relevant to a modern course in skeletal biology

The Skeletal System

The Skeletal System
A Book

by Olivier Pourquié

  • Publisher : Unknown Publisher
  • Release : 2009
  • Pages : 365
  • ISBN : 9780879698256
  • Language : En, Es, Fr & De
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Geared toward scientists and clinicians, this book summarizes the current understanding of the development, biology, and evolution of the vertebrate skeleton. It covers such topics as the differentiation of chondrocytes, the origins and evolution of bone, and the genetics of human skeletal disease.

Osteoimmunology

Osteoimmunology
Interactions of the Immune and Skeletal Systems

by Joseph Lorenzo,Mark Horowitz,Yongwon Choi,Georg Schett,Hiroshi Takayanagi

  • Publisher : Academic Press
  • Release : 2015-07-01
  • Pages : 376
  • ISBN : 9780128005712
  • Language : En, Es, Fr & De
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Osteoimmunology: Interactions of the Immune and Skeletal Systems, Second Edition, explores the advancements that have been made in the field during the last 40 years, including valuable information on our understanding of the interactions between hematopoietic, immune, and bone cells, now known as the field of osteoimmunology. This comprehensive work offers the most extensive summaries of research trends in the field and their translation into new therapeutics. Early chapters deal with the development of osteoblasts, osteoclasts, hematopoietic stem cells, T and B-lymphocytes, and communications between these cellular elements, while later sections contain discussions of the signaling pathways by which RANKL influences osteoclast development and function. Subsequent chapters explore the effects that estrogen has on bone and the immune system, the development of pathologic conditions, and the growing research around osteoporosis, Paget's disease, the genetics of bone disease, and bone cancer metastasis. Explains the intricate interaction between the immune system and bone Features detailed discussions of the key cellular and molecular mechanisms governing the homeostasis of the individual systems Facilitates greater understanding of osteoimmunologic networks, their environments, and how this understanding leads to better treatments for human diseases involving both systems

Skeletal Biology and Medicine II

Skeletal Biology and Medicine II
Bone and cartilage homeostasis and bone disease

by Mone Zaidi

  • Publisher : Wiley-Blackwell
  • Release : 2012-01-24
  • Pages : 88
  • ISBN : 9781573318563
  • Language : En, Es, Fr & De
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The volume features current basic, clinical, and translational research on aspects of skeletal morphogenesis and remodeling in health and disease. Papers survey vital new insights into the mechanisms of bone development and restructuring, including cellular and mechanical triggers, receptors and signaling pathways. Also covered are the effects of other physiological systems and disease states, such as immune system inflammation, diabetes, infection, and cancer on musculoskeletal health. Recent findings are shaping therapeutic directions that focus on both anti-resorptive and anabolic therapies. Basic scientists, clinical investigators, and clinicians with interests spanning endocrinology, physiology, cell biology, pathology, genetics, molecular biology, rheumatology, oncology, and other areas that relate to bone development and homeostasis will find this a valuable resource for the most recent developments in skeletal biology and medicine. This volume presents manuscripts stemming from the 4th New York Skeletal Biology and Medicine Conference, held at Mount Sinai School of Medicine in New York City on April 27–30, 2011. The papers included in this volume include two of the topic areas presented at the conference; the other topic areas are included in Skeletal Biology and Medicine I. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.1111/(ISSN)1749-6632. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

National Institutes of Health Annual Report of International Activities

National Institutes of Health Annual Report of International Activities
A Book

by John E. Fogarty International Center for Advanced Study in the Health Sciences

  • Publisher : Unknown Publisher
  • Release : 1985
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Skeletal Biology and Medicine II

Skeletal Biology and Medicine II
Bone and Cartilage Homeostasis and Bone Disease

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2011
  • Pages : 87
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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"This second of two volumes from the 4th New York Skeletal Biology and Medicine Conference, held at Mount Sinai School of Medicine in New York City on April 27-30, 2011, features papers focussed on bone and cartilage homeostasis and bone disease. The two volumes in this series, 1240 and 1237, present current basic, clinical, and translational research on aspects of skeletal morphogenesis and remodeling in health and disease. Papers survey vital new insights into the mechanisms of bone development and restructuring, including cellular and mechanical triggers, receptors and signaling pathways. Also covered are the effects of other physiological systems and disease states, such as immune system inflammation, diabetes, infection, and cancer on musculoskeletal health. Recent findings are shaping therapeutic directions that focus on both anti-resorptive and anabolic therapies. Basic scientists, clinical investigators, and clinicians with interests spanning endocrinology, physiology, cell biology, pathology, genetics, molecular biology, rheumatology, oncology, and other areas that relate to bone development and homeostasis will find this a valuable resource for the most recent developments in skeletal biology and medicine."--Academy website.

Skeletal Biology and Medicine

Skeletal Biology and Medicine
Bone and cartilage homeostasis and bone disease. II

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2011
  • Pages : 87
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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"This second of two volumes from the 4th New York Skeletal Biology and Medicine Conference, held at Mount Sinai School of Medicine in New York City on April 27-30, 2011, features papers focussed on bone and cartilage homeostasis and bone disease. The two volumes in this series, 1240 and 1237, present current basic, clinical, and translational research on aspects of skeletal morphogenesis and remodeling in health and disease. Papers survey vital new insights into the mechanisms of bone development and restructuring, including cellular and mechanical triggers, receptors and signaling pathways. Also covered are the effects of other physiological systems and disease states, such as immune system inflammation, diabetes, infection, and cancer on musculoskeletal health. Recent findings are shaping therapeutic directions that focus on both anti-resorptive and anabolic therapies. Basic scientists, clinical investigators, and clinicians with interests spanning endocrinology, physiology, cell biology, pathology, genetics, molecular biology, rheumatology, oncology, and other areas that relate to bone development and homeostasis will find this a valuable resource for the most recent developments in skeletal biology and medicine."--Academy website.

The Parathyroids

The Parathyroids
Basic and Clinical Concepts

by John P. Bilezikian,Robert Marcus,Michael A. Levine,Claudio Marcocci,Shonni J Silverberg,John T. Potts Jr.

  • Publisher : Academic Press
  • Release : 2014-09-09
  • Pages : 946
  • ISBN : 0123977908
  • Language : En, Es, Fr & De
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The third edition of The Parathyroids, led by a new stellar editorial team, has been thoroughly updated to reflect the considerable advances in just about every aspect of PTH biology over the past decade. It continues to be the authoritative reference that spans the basic science of parathyroid hormone treatment to major clinical disorders in a superb, single compendium. This translational resource is invaluable to graduate students, fellows, researchers, and research clinicians in the fields of endocrinology, bone biology, osteology, and rheumatology. Contains chapters and information on noninvasive imaging, fracture healing, secondary diseases such as CKD, Vitamin D, cell signaling pathways, vascular calcification, as well as advances in genetics/genomics Includes essential updates on the critical importance of Vitamin D insufficiency and its relationship to secondary hyperparathyroidism Offers new insights into the underlying mechanisms of parathyroid hormone actions on osteocytes and sclerostin Examines essential updates in the understanding of secondary hyperparathyroidism associated with chronic kidney disease, facture healing, and vascular disease

Advances in Pathobiology and Management of Paget’s Disease of Bone

Advances in Pathobiology and Management of Paget’s Disease of Bone
A Book

by Sakamuri V. Reddy

  • Publisher : Academic Press
  • Release : 2016-04-28
  • Pages : 158
  • ISBN : 012809690X
  • Language : En, Es, Fr & De
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Advances in Pathobiology and Management of Paget’s Disease of Bone presents an essential collection of up-to-date knowledge about the pathophysiology, genetics, and treatment of Paget’s disease. It covers the comprehensive information related to clinical perspectives, epidemiology, genetics, environmental factors such as viral etiology, molecular abnormalities, complications such as osteosarcoma, and current and future treatment for Paget’s disease. This book serves as a useful volume for basic scientists, graduate students, and practicing clinicians in understanding the pathobiology, etiology, and treatment of this disease. Discusses the current research of the nature of Paget’s disease and its response to the latest treatments which are seminal in the management of this disease Helps users quickly assess the very latest details on the diverse scientific and clinical aspects of Paget’s disease, as opposed to searching through multiple journal articles in the literature Presents work from featured leaders in Paget’s disease around the globe Serves as a useful volume for basic scientists, graduate students, and practicing clinicians in understanding the pathobiology, etiology, and treatment of this disease

The Genetics of the Skeleton

The Genetics of the Skeleton
Animal Models of Skeletal Development

by David Roderick Johnson

  • Publisher : Oxford University Press, USA
  • Release : 1986
  • Pages : 407
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The effects of genetic mutations on the mammalian skeleton are a useful aid in understanding how the skeleton develops. This book describes these effects, using the mouse as a primary source for considering the precartilaginous, cartilaginous, and bony skeletons, regional anatomy, and the interactions between genes and teratogens. The author summarizes the normal development of each part before discussing its mutations and completes his study by synthesizing the contributions mutants make to our understanding of the development of each part considered.

Vertebrate Skeletal Development

Vertebrate Skeletal Development
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2019-03-20
  • Pages : 409
  • ISBN : 0128104880
  • Language : En, Es, Fr & De
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Vertebrate Skeletal Development, Volume 133, the latest release in the Current Topics in Developmental Biology series, presents interesting chapters on a variety of topics, with this edition focusing on Craniofacial skeletal development, Regulatory mechanism of jawbone and tooth development, Development of the axial skeleton and intervertebral discs, Stem and progenitor cells in skeletal development, Origin, functioning and morphogenetic activity of limb synovial joint, ECM signaling in cartilage development and endochondral ossification, Sox genes in skeletal development, Wnt-Signaling in Skeletal Development, Gαs signaling in skeletal development and diseases, FGF signaling in skeletal development, Bone morphogenetic growth factors in bone development, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology series Includes the latest information on Vertebrate Skeletal Development

Skeletal Biology and Medicine I

Skeletal Biology and Medicine I
Mechanisms Regulating Bone Mass, Volume 1237

by Mone Zaidi

  • Publisher : Wiley-Blackwell
  • Release : 2011-12-12
  • Pages : 252
  • ISBN : 9781573318464
  • Language : En, Es, Fr & De
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The volume features current basic, clinical, and translational research on aspects of skeletal morphogenesis and remodeling in health and disease. Papers survey vital new insights into the mechanisms of bone development and restructuring, including cellular and mechanical triggers, receptors and signaling pathways. Also covered are the effects of other physiological systems and disease states, such as immune system inflammation, diabetes, infection, and cancer on musculoskeletal health. Recent findings are shaping therapeutic directions that focus on both anti-resorptive and anabolic therapies. Basic scientists, clinical investigators, and clinicians with interests spanning endocrinology, physiology, cell biology, pathology, genetics, molecular biology, rheumatology, oncology, and other areas that relate to bone development and homeostasis will find this a valuable resource for the most recent developments in skeletal biology and medicine. This volume presents manuscripts stemming from the 4th New York Skeletal Biology and Medicine Conference, held at Mount Sinai School of Medicine in New York City on April 27–30, 2011. The papers included in this volume include two of the topic areas presented at the conference; the other topic areas are included in Skeletal Biology and Medicine II. NOTE: Annals volumes are available for sale as individual books or as a journal. For information about institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.1111/(ISSN)1749-6632. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Fundamentals of Osteoporosis

Fundamentals of Osteoporosis
A Book

by Robert Marcus,David Feldman,Dorothy Nelson

  • Publisher : Unknown Publisher
  • Release : 2009-08-01
  • Pages : 537
  • ISBN : 9780123750983
  • Language : En, Es, Fr & De
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A comprehensive source of the basic research related to osteoporosis. It introduces genomic and proteomic analysis, histopathology and imaging, as well cellular and molecular mechanisms relevant to assay development and drug discovery.

Paediatric Osteology

Paediatric Osteology
New Developments in Diagnostics and Therapy : Proceedings of the First International Workshop on Paediatric Osteology, 5-7 October, 1995, Cologne, Germany

by Eckhard Schönau

  • Publisher : Elsevier Science Health Science Division
  • Release : 1996
  • Pages : 304
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Hardbound. These proceedings consist of papers of the First European Workshop on Paediatric Osteology.The aim of this workshop was to evaluate current experience with childhood bone diseases from multi-disciplinary points of view. New data on the development of the skeletal system in childhood received special emphasis. Current results and methods of molecular biology and new genes in skeletal diseases as chondrodysplasias, disorders of calcium and phosphate metabolism and osteoporosis are presented. The different methods of bone densitometry, their problems and normative data in childhood are introduced. Altogether many new aspects and possiblilties have been shown which could lead to improvement in the diagnostic and therapeutic care of patients with childhood skeletal disease. This book will be of interest to paediatricians and endocinologists as well as those involved in Internal medicine, osteology, preventative medicine, genetics and sport medici