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Responsible Genomic Data Sharing

Responsible Genomic Data Sharing
Challenges and Approaches

by Xiaoqian Jiang,Haixu Tang

  • Publisher : Academic Press
  • Release : 2020-03-14
  • Pages : 210
  • ISBN : 0128163399
  • Language : En, Es, Fr & De
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Responsible Genomic Data Sharing: Challenges and Approaches brings together international experts in genomics research, bioinformatics and digital security who analyze common challenges in genomic data sharing, privacy preserving technologies, and best practices for large-scale genomic data sharing. Practical case studies, including the Global Alliance for Genomics and Health, the Beacon Network, and the Matchmaker Exchange, are discussed in-depth, illuminating pathways forward for new genomic data sharing efforts across research and clinical practice, industry and academia. Addresses privacy preserving technologies and how they can be applied to enable responsible genomic data sharing Employs illustrative case studies and analyzes emerging genomic data sharing efforts, common challenges and lessons learned Features chapter contributions from international experts in responsible approaches to genomic data sharing

An Introduction to Statistical Genetic Data Analysis

An Introduction to Statistical Genetic Data Analysis
A Book

by Melinda C. Mills,Nicola Barban,Felix C. Tropf

  • Publisher : MIT Press
  • Release : 2020-02-18
  • Pages : 432
  • ISBN : 0262538385
  • Language : En, Es, Fr & De
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A comprehensive introduction to modern applied statistical genetic data analysis, accessible to those without a background in molecular biology or genetics. Human genetic research is now relevant beyond biology, epidemiology, and the medical sciences, with applications in such fields as psychology, psychiatry, statistics, demography, sociology, and economics. With advances in computing power, the availability of data, and new techniques, it is now possible to integrate large-scale molecular genetic information into research across a broad range of topics. This book offers the first comprehensive introduction to modern applied statistical genetic data analysis that covers theory, data preparation, and analysis of molecular genetic data, with hands-on computer exercises. It is accessible to students and researchers in any empirically oriented medical, biological, or social science discipline; a background in molecular biology or genetics is not required. The book first provides foundations for statistical genetic data analysis, including a survey of fundamental concepts, primers on statistics and human evolution, and an introduction to polygenic scores. It then covers the practicalities of working with genetic data, discussing such topics as analytical challenges and data management. Finally, the book presents applications and advanced topics, including polygenic score and gene-environment interaction applications, Mendelian Randomization and instrumental variables, and ethical issues. The software and data used in the book are freely available and can be found on the book's website.

Evaluation of a Trust-enabled Framework for Genomic Data Sharing Within an Insurance Context

Evaluation of a Trust-enabled Framework for Genomic Data Sharing Within an Insurance Context
An Experimental Vignette Study

by Mattia Preda

  • Publisher : Unknown Publisher
  • Release : 2017
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Digital Personalized Health and Medicine

Digital Personalized Health and Medicine
Proceedings of MIE 2020

by L.B. Pape-Haugaard,C. Lovis,I. Cort Madsen

  • Publisher : IOS Press
  • Release : 2020-06-17
  • Pages : 1496
  • ISBN : 1643680838
  • Language : En, Es, Fr & De
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Digital health and medical informatics have grown in importance in recent years, and have now become central to the provision of effective healthcare around the world. This book presents the proceedings of the 30th Medical Informatics Europe conference (MIE). This edition of the conference, hosted by the European Federation for Medical Informatics (EFMI) since the 1970s, was due to be held in Geneva, Switzerland in April 2020, but as a result of measures to prevent the spread of the Covid19 pandemic, the conference itself had to be cancelled. Nevertheless, because this collection of papers offers a wealth of knowledge and experience across the full spectrum of digital health and medicine, it was decided to publish the submissions accepted in the review process and confirmed by the Scientific Program Committee for publication, and these are published here as planned. The 232 papers are themed under 6 section headings: biomedical data, tools and methods; supporting care delivery; health and prevention; precision medicine and public health; human factors and citizen centered digital health; and ethics, legal and societal aspects. A 7th section deals with the Swiss personalized health network, and section 8 includes the 125 posters accepted for the conference. Offering an overview of current trends and developments in digital health and medical informatics, the book provides a valuable information resource for researchers and health practitioners alike.

Federal Register

Federal Register
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2012-10
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2016

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2016
Hearings Before a Subcommittee of the Committee on Appropriations, House of Representatives, One Hundred Fourteenth Congress, First Session

by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies

  • Publisher : Unknown Publisher
  • Release : 2015
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Factors in Genetic Data Sharing Decisions

Factors in Genetic Data Sharing Decisions
A Book

by William Robert Aurite

  • Publisher : Unknown Publisher
  • Release : 2019
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Recent technological advances have transformed genomic and genetic research. Genome- wide association studies enable scientists to identify specific genetic variants that may be linked to risks for certain diseases. The ability of these studies to find new associations is dependent on both the availability and quantity of genetic data. The availability of genetic data is predicated, in part, by the willingness of an individual to share genetic data. Despite the importance of data sharing in such studies, not much is known about the factors that may impact genetic data sharing decisions. Personal and interdependent privacy considerations in these decisions are also not well understood. Direct-to-Consumer (DTC) genetic testing services are an emergent and potentially rich source for genetic data. In order for this data to be leveraged in a research domain, users must first elect to share their data. The number of individuals subscribing to DTC services is expected to increase, further necessitating the need for a more complete understanding of factors contributing to sharing decisions. This dissertation is structured to address aforementioned and other lines of inquiry in the form of five studies. The first study in this dissertation examines privacy concerns and likely use factors that may help shape an individual's decision to take a genetic test. The second, third, and fourth studies develop numerous regression and classification models for the intention to share genetic data. Specific focus is paid to the socioeconomic, sociodemographic, and relevant experience factors. The fifth study presented in this dissertation addresses an important aspect of genetic research, diversity. In this study, Indigenous perspectives on DTC genetic testing services are explored with careful attention paid to barriers and motivators of involvement in genetic testing. Together, these studies form a comprehensive understanding of the factors that impact genetic data sharing decisions. This dissertation and its findings have implications for both medical and commercial research, specifically in regards to targeted recruitment and data acquisition strategies.

Analysis of High Level Patterns in Genomic Data

Analysis of High Level Patterns in Genomic Data
From Protein Thermostability to Tumor Biology

by Brian Daniel O'Connor

  • Publisher : Unknown Publisher
  • Release : 2007
  • Pages : 390
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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International Journal of Micrographics & Optical Technology

International Journal of Micrographics & Optical Technology
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2002
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Genetic Diversity and Genomics of the Immune Response

Genetic Diversity and Genomics of the Immune Response
A Book

by Daniel E. Geroghty

  • Publisher : Unknown Publisher
  • Release : 2002
  • Pages : 206
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Ethical challenges as we approach the end of the Human Genome Project

Ethical challenges as we approach the end of the Human Genome Project
A Book

by Darryl Raymund Johnson Macer,Eubios Ethics Institute

  • Publisher : Unknown Publisher
  • Release : 2000
  • Pages : 123
  • ISBN : 9780908897155
  • Language : En, Es, Fr & De
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Proceedings of the New Zealand Society of Animal Production ... Annual Conference

Proceedings of the New Zealand Society of Animal Production ... Annual Conference
A Book

by New Zealand Society of Animal Production,New Zealand Society of Animal Production. Annual Conference

  • Publisher : Unknown Publisher
  • Release : 2006
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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C D A Journal

C D A Journal
A Book

by California Dental Association

  • Publisher : Unknown Publisher
  • Release : 2010-07
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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IBM Systems Journal

IBM Systems Journal
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2006
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Privacy-preserving Genomic Data Publishing Via Differential Privacy

Privacy-preserving Genomic Data Publishing Via Differential Privacy
A Book

by Tanya Khatri

  • Publisher : Unknown Publisher
  • Release : 2018
  • Pages : 68
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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"Privacy-preserving data publishing is a mechanism for sharing data while ensuring the privacy of individuals is preserved in the published data and utility is maintained for data mining and analysis. There is a huge need for sharing genomic data to advance medical and health research. However, since genomic data is highly sensitive and the ultimate identifier, it is a big challenge to publish genomic data while protecting the privacy of individuals in the data. In this thesis, we address the aforementioned challenge by presenting an approach for privacy-preserving genomic data publishing via differentially-private suffix tree. The proposed algorithm uses a top-down approach and utilizes Laplace mechanism to divide the raw genomic data into disjoint partitions, and then normalize the partitioning structure to ensure consistency and maintain utility. The output of our algorithm is a differentially-private suffix tree, a data structure most suitable for efficient search on genomic data. We experiment on real-life genomic data obtained from the Human Genome Privacy Challenge project, and we show that our approach is efficient, scalable, and achieves high utility with respect to genomic sequence matching count queries."--Boise State University ScholarWorks.

Proceedings of the ... Australian Wine Industry Technical Conference

Proceedings of the ... Australian Wine Industry Technical Conference
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2005
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Autoimmunity, Part B

Autoimmunity, Part B
Novel Applications of Basic Research

by M. Eric Gershwin,Yehuda Shoenfeld

  • Publisher : Wiley-Blackwell
  • Release : 2007-10-08
  • Pages : 752
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The incidence of autoimmune diseases is increasing worldwide, and the search for better management of these diseases and even for a cure is being pursued by scientists from many disciplines. Tools from the areas of genetics, neuroscience, cell biology, virology, and infectious disease are being applied to the problem and are yielding useful results. This is the second volume of a series of four on autoimmunity, and findings related to particular organs, organ systems, and diseases are presented. The focus in Part B is on genetics and advances in treatment. Part A presents new principles in autoimmunity and new diagnostic tools. See Parts C and D for clinical venues in autoimmunity. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member.

Thomas' Hematopoietic Cell Transplantation

Thomas' Hematopoietic Cell Transplantation
A Book

by E. Donnall Thomas

  • Publisher : Wiley-Blackwell
  • Release : 2009-04-13
  • Pages : 1718
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Accompanying CD-ROM contains ... "full content of the book, database of figures, search function."--CD-ROM label.

Proceedings of the IXth International Conference on Grape Genetics and Breeding

Proceedings of the IXth International Conference on Grape Genetics and Breeding
Udine, Italy July 2-6, 2006

by Enrico Peterlunger,Gabriele Di Gaspero,Guido Cipriani

  • Publisher : Unknown Publisher
  • Release : 2009
  • Pages : 640
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Evolutionary Analyses of Genomic Data

Evolutionary Analyses of Genomic Data
A Book

by Aaron E. Hirsh

  • Publisher : Unknown Publisher
  • Release : 2003
  • Pages : 168
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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