Download How to Optimize Fluid Bed Processing Technology Ebook PDF

How to Optimize Fluid Bed Processing Technology: Part of the Expertise in Pharmaceutical Process Technology Series addresses the important components of fluid bed granulation, providing answers to problems that commonly arise and using numerous practical examples and case studies as reference. This book covers the theoretical concepts involved in fluidization, also providing a description of the choice and functionality of equipment. Additional chapters feature key aspects of the technology, including formulation requirements, process variables, process scale-up, troubleshooting, new development, safety, and process evaluation. Given its discussion of theoretical principles and practical solutions, this is a go-to resource for all those scientists and new researchers working with fluid bed granulation as a unit operation. Written by an expert in the field with several years of experience in product development, manufacturing, plant operations, and process engineering Illustrates when fluid bed granulation is needed, when to use less common fluid bed granulation methods, and the advantages of fluid bed granulation when compared to other granulation techniques Offers troubleshooting tips and practical advice for scientists working with this technique

Authored by leading experts from academia, users and manufacturers, this book provides an authoritative account of the science and technology involved in multiparticulate drug delivery systems which offer superior clinical and technical advantages over many other specialized approaches in drug delivery. The book will cover market trends, potential benefits and formulation challenges for various types of multiparticulate systems. Drug solubility, dose, chemistry and therapeutic indications as well as excipient suitability coupled with manufacturing methods will be fully covered. Key approaches for taste-masking, delayed release and extended release of multiparticulates systems are of significant interest, especially their in-vivo and in-vitro performance. In addition, the principles of scale-up, QbD, and regulatory aspects of common materials used in this technology will be explained, as well as recent advances in materials and equipment enabling robust, flexible and cost-effective manufacture. Case studies illustrating best practices will also make the book a valuable resource to pharmaceutical scientists in industry and academia.

The Third Edition presents all pharmaceutical industry personnel and those in academia with critical updates on the recent advances in granulation technology and changes in FDA regulatory guidelines. Addressing precisely how these recent innovations and revisions affect unit operation of particle generation and granulation, this text assists the re

The proceedings of the 20th International Conference on Fluidized Bed Combustion (FBC) collect 9 plenary lectures and 175 peer-reviewed technical papers presented in the conference held in Xi'an China in May 18-21,2009. The conference was the 20th conference in a series, covering the latest fundamental research results, as well as the application experience from pilot plants, demonstrations and industrial units regarding to the FBC science and technology. It was co-hosted by Tsinghua University, Southeast University, Zhejiang University, China Electricity Council and Chinese Machinery Industry Federation. A particular feature of the proceedings is the balance between the papers submitted by experts from industry and the papers submitted by academic researchers, aiming to bring academic knowledge to application as well as to define new areas for research. The authors of the proceedings are the most active researchers, technology developers, experienced and representative facility operators and manufacturers. They presented the latest research results, state-of-the-art development and projects, and the useful experience. The proceedings are divided into following sections: • CFB Boiler Technology, Operation and Design • Fundamental Research on Fluidization and Fluidized Combustion • C02 Capture and Chemical Looping • Gasification • Modeling and Simulation on FBC Technology • Environments and Pollutant Control • Sustainable Fuels The proceedings can be served as idea references for researchers, engineers, academia and graduate students, plant operators, boiler manufacturers, component suppliers, and technical managers who work on FBC fundamental research, technology development and industrial application.

· Explains operation and scientific fundamentals of circulating fluidized bed (CFB) boilers · Outlines practical issues in industrial use · Teaches how to optimize design for maximum reliability and efficiency · Discusses operating and maintenance issues and how to troubleshoot them This book provides practicing engineers and students with insight into the design and operation of circulating fluidized bed (CFB) boilers through a combination of theoretical concepts and practical experience. An emphasis on combustion, hydrodynamics, heat transfer, and material issues illustrates these concepts with numerous examples from actual operating plants. The relevance of design and feed-stock parameters to the operation of a CFB boiler are also examined, along with their impacts on designs of mechanical components, including cyclones, air distributor grids, and solid recycle systems. This versatile resource explains how fluidized bed equipment works and how the basic principles of thermodynamics and fluid mechanics influence design, while providing insight into planning new projects, troubleshooting existing equipment, and appreciating the capabilities and limitations of the process. From hydrodynamics to construction and maintenance, the author covers all of the essential information needed to understand, design, operate, and maintain a complete fluidized bed system. It is a must for clean coal technology as well as for biomass power generation.

Chiangmai, Thailand, 18-20 July 2008

Fluidization is a technique that enables solid particles to take on some of the properties of a fluid. Despite being very widely used within the food processing industry, understanding of this important technique is often limited. Applications of Fluidization to Food Processing sets out the established theory of fluidization and relates this to food processing applications, particularly in: • Drying • Freezing • Mixing • Granulation • Fermentation This important and thorough book, written by Peter Smith, who has many years’ experience teaching and researching in food processing, is an essential tool and reference for food scientists and technologists, and engineers working within the food industry. Libraries, and research and development groups within all universities and research establishments where food science, food studies, food technology, physics and engineering are studied and taught should have copies of this useful book.

Essentials & Applications of Food Engineering provides a comprehensive understanding of food engineering operations and their practical and industrial utility. It presents pertinent case studies, solved numerical problems, and multiple choice questions in each chapter and serves as a ready reference for classroom teaching and exam preparations. The first part of this textbook contains the introductory topics on units and dimensions, material balance, energy balance, and fluid flow. The second part deals with the theory and applications of heat and mass transfer, psychrometry, and reaction kinetics. The subsequent chapters of the book present the heat and mass transfer operations such as evaporation, drying, refrigeration, freezing, mixing, and separation. The final section focuses on the thermal, non-thermal, and nanotechnology-based novel food processing techniques, 3D food printing, active and intelligent food packaging, and fundamentals of CFD modeling. Features Features 28 case studies to provide a substantial understanding of the practical and industrial applications of various food engineering operations Includes 178 solved numerical problems and 285 multiple choice questions Highlights the application of mass balance in food product traceability and the importance of viscosity measurement in a variety of food products Provides updated information on novel food processing techniques such as cold plasma, 3D food printing, nanospray drying, electrospraying, and electrospinning The textbook is designed for undergraduate and graduate students pursuing Food Technology and Food Process Engineering courses. This book would also be of interest to course instructors and food industry professionals.

Handbook of Pharmaceutical Wet Granulation: Theory and Practice in a Quality by Design Paradigm offers a single and comprehensive reference dedicated to all aspects of pharmaceutical wet granulation, taking a holistic approach by combining introductory principles with practical solutions. Chapters are written by international experts across industry, academic and regulatory settings, and cover a wide spectrum of relevant and contemporary wet granulation topics, techniques and processes. The books' focus on process analytical technology, quality by design principles, granulation equipment, modeling, scale-up, control and real time release makes it a timely and valuable resource for all those involved in pharmaceutical wet granulation. Discusses fundamentals of theory and current industrial practice in the field of wet granulation, including product and process design and role of material properties in wet granulation Examines the modern evolution of wet granulation through current topics such as established and novel process analytical technologies (PATs), and product development and scale-up paradigms Written for scientists working within the pharmaceutical industry, as well as academics, regulatory officials and equipment vendors who provide PAT tools and granulation equipment

Fluidized bed (FB) combustion and gasification are advanced techniques for fuel flexible, high efficiency and low emission conversion. Fuels are combusted or gasified as a fluidized bed suspended by jets with sorbents that remove harmful emissions such as SOx. CO2 capture can also be incorporated. Fluidized bed technologies for near-zero emission combustion and gasification provides an overview of established FB technologies while also detailing recent developments in the field. Part one, an introductory section, reviews fluidization science and FB technologies and includes chapters on particle characterization and behaviour, properties of stationary and circulating fluidized beds, heat and mass transfer and attrition in FB combustion and gasification systems. Part two expands on this introduction to explore the fundamentals of FB combustion and gasification including the conversion of solid, liquid and gaseous fuels, pollutant emission and reactor design and scale up. Part three highlights recent advances in a variety of FB combustion and gasification technologies before part four moves on to focus on emerging CO2 capture technologies. Finally, part five explores other applications of FB technology including (FB) petroleum refining and chemical production. Fluidized bed technologies for near-zero emission combustion and gasification is a technical resource for power plant operators, industrial engineers working with fluidized bed combustion and gasification systems and researchers, scientists and academics in the field. Examines the fundamentals of fluidized bed (FB) technologies, including the conversion of solid, liquid and gaseous fuels Explores recent advances in a variety of technologies such as pressurized FB combustion, and the measurement, monitoring and control of FB combustion and gasification Discusses emerging technologies and examines applications of FB in other processes