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Human Population Genetics and Genomics

Human Population Genetics and Genomics
A Book

by Alan R. Templeton

  • Publisher : Academic Press
  • Release : 2018-11-08
  • Pages : 498
  • ISBN : 0123860261
  • Language : En, Es, Fr & De
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Human Population Genetics and Genomics provides researchers/students with knowledge on population genetics and relevant statistical approaches to help them become more effective users of modern genetic, genomic and statistical tools. In-depth chapters offer thorough discussions of systems of mating, genetic drift, gene flow and subdivided populations, human population history, genotype and phenotype, detecting selection, units and targets of natural selection, adaptation to temporally and spatially variable environments, selection in age-structured populations, and genomics and society. As human genetics and genomics research often employs tools and approaches derived from population genetics, this book helps users understand the basic principles of these tools. In addition, studies often employ statistical approaches and analysis, so an understanding of basic statistical theory is also needed. Comprehensively explains the use of population genetics and genomics in medical applications and research Discusses the relevance of population genetics and genomics to major social issues, including race and the dangers of modern eugenics proposals Provides an overview of how population genetics and genomics helps us understand where we came from as a species and how we evolved into who we are now

Genomic Diversity

Genomic Diversity
Applications in Human Population Genetics ; [proceedings of a Symposium on Molecular Anthropology in the Twenty-First Century, Held During the 14th International Congress of the Association of Anthropological and Ethnological Sciences, Held July 26 - August 1, 1998, in Williamsburg, Virginia]

by Surinder Singh Papiha,Ranjan Deka,Ranajit Chakraborty

  • Publisher : Springer Science & Business Media
  • Release : 1999-10-31
  • Pages : 246
  • ISBN : 9780306462955
  • Language : En, Es, Fr & De
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Proceedings of the Symposium on Molecular Anthropology in the 21st Century, held during the 14th International Congress of the Association of Anthropological and Ethnological Sciences, 26 July to 1 August, 1998, in Williamsburg, Virginia, USA

A Primer of Population Genetics and Genomics

A Primer of Population Genetics and Genomics
A Book

by Daniel L. Hartl

  • Publisher : Oxford University Press, USA
  • Release : 2020-06-25
  • Pages : 320
  • ISBN : 0198862296
  • Language : En, Es, Fr & De
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This accessible primer has been completely revised and updated to provide a concise but comprehensive introduction to the basic concepts of population genetics and genomics.

The Genetics of Human Populations

The Genetics of Human Populations
A Book

by Luigi Luca Cavalli-Sforza,Walter Fred Bodmer

  • Publisher : Courier Corporation
  • Release : 1999
  • Pages : 965
  • ISBN : 0486406938
  • Language : En, Es, Fr & De
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Comprehensive, advanced treatment of nature and source of inherited characteristics, with treatment of mathematical techniques. Mendelian populations, mutations, polymorphisms, genetic demography, much more. Emphasizes interpretation of data in relation to theoretical models.

Genetics

Genetics
Analysis of Genes and Genomes

by Daniel L. Hartl,Elizabeth W. Jones

  • Publisher : Jones & Bartlett Learning
  • Release : 2005
  • Pages : 854
  • ISBN : 9780763715113
  • Language : En, Es, Fr & De
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Biological Sciences

Forward-Time Population Genetics Simulations

Forward-Time Population Genetics Simulations
Methods, Implementation, and Applications

by Bo Peng,Marek Kimmel,Christopher I. Amos

  • Publisher : John Wiley & Sons
  • Release : 2012-02-14
  • Pages : 234
  • ISBN : 0470503483
  • Language : En, Es, Fr & De
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The rapid increase of the power of personal computers has led to the use of serious simulation programs such as easy POP in genetic studies. This book summarizes recent advances in forward-time simulation methods and demonstrates their applications in population genetics and genetic epidemiology. The authors introduce commonly used forward-time population genetics simulation methods, including some new methods, and introduce a forward-time population genetics simulation environment, simuPOP, as a powerful and flexible tool to implement these simulations. Researchers and students in population and statistical genetics will find this book useful.

Human Genetics and Genomics

Human Genetics and Genomics
A Book

by Bruce R. Korf,Mira B. Irons

  • Publisher : John Wiley & Sons
  • Release : 2012-11-19
  • Pages : 280
  • ISBN : 1118537661
  • Language : En, Es, Fr & De
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This fourth edition of the best-selling textbook, Human Genetics and Genomics, clearly explains the key principles needed by medical and health sciences students, from the basis of molecular genetics, to clinical applications used in the treatment of both rare and common conditions. A newly expanded Part 1, Basic Principles of Human Genetics, focuses on introducing the reader to key concepts such as Mendelian principles, DNA replication and gene expression. Part 2, Genetics and Genomics in Medical Practice, uses case scenarios to help you engage with current genetic practice. Now featuring full-color diagrams, Human Genetics and Genomics has been rigorously updated to reflect today’s genetics teaching, and includes updated discussion of genetic risk assessment, “single gene” disorders and therapeutics. Key learning features include: Clinical snapshots to help relate science to practice ‘Hot topics’ boxes that focus on the latest developments in testing, assessment and treatment ‘Ethical issues’ boxes to prompt further thought and discussion on the implications of genetic developments ‘Sources of information’ boxes to assist with the practicalities of clinical research and information provision Self-assessment review questions in each chapter Accompanied by the Wiley E-Text digital edition (included in the price of the book), Human Genetics and Genomics is also fully supported by a suite of online resources at www.korfgenetics.com, including: Factsheets on 100 genetic disorders, ideal for study and exam preparation Interactive Multiple Choice Questions (MCQs) with feedback on all answers Links to online resources for further study Figures from the book available as PowerPoint slides, ideal for teaching purposes The perfect companion to the genetics component of both problem-based learning and integrated medical courses, Human Genetics and Genomics presents the ideal balance between the bio-molecular basis of genetics and clinical cases, and provides an invaluable overview for anyone wishing to engage with this fast-moving discipline.

Human Evolutionary Genetics, Second Edition

Human Evolutionary Genetics, Second Edition
A Book

by Mark Jobling,Edward Hollox,Matthew Hurles,Toomas Kivisild,Chris Tyler-Smith

  • Publisher : Garland Science
  • Release : 2013-06-23
  • Pages : 650
  • ISBN : 131795226X
  • Language : En, Es, Fr & De
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Now in full-color, the Second Edition of Human Evolutionary Genetics has been completely revised to cover the rapid advances in the field since publication of the highly regarded First Edition. Written for upper-level undergraduate and graduate students, it is the only textbook to integrate genetic, archaeological, and linguistic perspectives on human evolution, and to offer a genomic perspective, reflecting the shift from studies of specific regions of the genome towards comprehensive genomewide analyses of human genetic diversity. Human Evolutionary Genetics is suitable for courses in Genetics, Evolution, and Anthropology. Those readers with a background in anthropology will find that the streamlined genetic analysis material contained in the Second Edition is more accessible. The new edition also integrates new technologies (including next-generation sequencing and genome-wide SNP typing) and new data analysis methods, including recent data on ancient genomes and their impact on our understanding of human evolution. The book also examines the subject of personal genomics and its implications.

Human Genes and Genomes

Human Genes and Genomes
Science, Health, Society

by Leon E. Rosenberg,Diane Drobnis Rosenberg

  • Publisher : Academic Press
  • Release : 2012-05-21
  • Pages : 446
  • ISBN : 0123852137
  • Language : En, Es, Fr & De
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In the nearly 60 years since Watson and Crick proposed the double helical structure of DNA, the molecule of heredity, waves of discoveries have made genetics the most thrilling field in the sciences. The study of genes and genomics today explores all aspects of the life with relevance in the lab, in the doctor’s office, in the courtroom and even in social relationships. In this helpful guidebook, one of the most respected and accomplished human geneticists of our time communicates the importance of genes and genomics studies in all aspects of life. With the use of core concepts and the integration of extensive references, this book provides students and professionals alike with the most in-depth view of the current state of the science and its relevance across disciplines. Bridges the gap between basic human genetic understanding and one of the most promising avenues for advances in the diagnosis, prevention and treatment of human disease. Includes the latest information on diagnostic testing, population screening, predicting disease susceptibility, pharmacogenomics and more Explores ethical, legal, regulatory and economic aspects of genomics in medicine. Integrates historical (classical) genetics approach with the latest discoveries in structural and functional genomics

Population Genomics

Population Genomics
Concepts, Approaches and Applications

by Om P. Rajora

  • Publisher : Springer
  • Release : 2019-01-07
  • Pages : 822
  • ISBN : 3030045897
  • Language : En, Es, Fr & De
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Population genomics has revolutionized various disciplines of biology including population, evolutionary, ecological and conservation genetics, plant and animal breeding, human health, medicine and pharmacology by allowing to address novel and long-standing questions with unprecedented power and accuracy. It employs large-scale or genome-wide genetic information and bioinformatics to address various fundamental and applied aspects in biology and related disciplines, and provides a comprehensive genome-wide perspective and new insights that were not possible before. These advances have become possible due to the development of new and low-cost sequencing and genotyping technologies and novel statistical approaches and software, bioinformatics tools, and models. Population genomics is tremendously advancing our understanding the roles of evolutionary processes, such as mutation, genetic drift, gene flow, and natural selection, in shaping up genetic variation at individual loci and across the genome and populations; improving the assessment of population genetic parameters or processes such as adaptive evolution, effective population size, gene flow, admixture, inbreeding and outbreeding depression, demography, and biogeography; resolving evolutionary histories and phylogenetic relationships of extant, ancient and extinct species; understanding the genomic basis of fitness, adaptation, speciation, complex ecological and economically important traits, and disease and insect resistance; facilitating forensics, genetic medicine and pharmacology; delineating conservation genetic units; and understanding the genetic effects of resource management practices, and assisting conservation and sustainable management of genetic resources. This Population Genomics book discusses the concepts, approaches, applications and promises of population genomics in addressing most of the above fundamental and applied crucial aspects in a variety of organisms from microorganisms to humans. The book provides insights into a range of emerging population genomics topics including population epigenomics, landscape genomics, seascape genomics, paleogenomics, ecological and evolutionary genomics, biogeography, demography, speciation, admixture, colonization and invasion, genomic selection, and plant and animal domestication. This book fills a vacuum in the field and is expected to become a primary reference in Population Genomics world-wide.

Population Genetics and Microevolutionary Theory

Population Genetics and Microevolutionary Theory
A Book

by Alan R. Templeton

  • Publisher : John Wiley & Sons
  • Release : 2006-09-29
  • Pages : 720
  • ISBN : 0470047216
  • Language : En, Es, Fr & De
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The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links

Progress in Population Genetics and Human Evolution

Progress in Population Genetics and Human Evolution
A Book

by Peter Donnelly,Simon Tavare

  • Publisher : Springer Verlag
  • Release : 1997-02-27
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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This book is devoted to the collection, interpretation and analysis of population genetic data. Among the topics included here are studies on human evolutionary history, molecular techniques for generating data, statistical and computational techniques for the interpretation of such data, and stochastic models for genealogy and population structure. The chapters reflect the close interaction between experimental molecular biologists and theoreticians. The book will be useful for specialists in the area, as well as mathematicians, statisticians, computer scientists and biologists wanting a brief overview of current problems in the field.

The History and Geography of Human Genes

The History and Geography of Human Genes
Abridged paperback Edition

by Luigi Luca Cavalli-Sforza,Paolo Menozzi,Alberto Piazza

  • Publisher : Princeton University Press
  • Release : 2018-06-05
  • Pages : 413
  • ISBN : 0691187266
  • Language : En, Es, Fr & De
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Hailed as a breakthrough in the understanding of human evolution, The History and Geography of Human Genes offers the first full-scale reconstruction of where human populations originated and the paths by which they spread throughout the world. By mapping the worldwide geographic distribution of genes for over 110 traits in over 1800 primarily aboriginal populations, the authors charted migrations and devised a clock by which to date evolutionary history. This monumental work is now available in a more affordable paperback edition without the myriad illustrations and maps, but containing the full text and partial appendices of the authors' pathbreaking endeavor.

Human Genetics

Human Genetics
Race, Population, and Disease

by Russ Hodge

  • Publisher : Infobase Publishing
  • Release : 2010-01-01
  • Pages : 228
  • ISBN : 0816066825
  • Language : En, Es, Fr & De
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Describes modern developments in the field of genetics, discussing the mapping of the human genome, the genetic causes of afflictions, and genetic modification.

Human Evolutionary Genetics

Human Evolutionary Genetics
Origins, Peoples & Disease

by Mark A. Jobling,Matthew Hurles,Chris Tyler-Smith

  • Publisher : Garland Pub
  • Release : 2004
  • Pages : 523
  • ISBN : 9780815341857
  • Language : En, Es, Fr & De
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'Human Evolutionary Genetics' describes the molecular basis of human genetic variation and the mechanisms which give rise to it. It introduces principles behind the use of molecular genetic data to understand human evolution and population histories.

Essential Genetics

Essential Genetics
A Genomics Perspective

by Daniel Hartl

  • Publisher : Jones & Bartlett Learning
  • Release : 2011
  • Pages : 575
  • ISBN : 0763773646
  • Language : En, Es, Fr & De
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Updated to reflect the latest discoveries in the field, the Fifth Edition of Hartl's classic text provides an accessible, student-friendly introduction to contemporary genetics. Designed for the shorter, less comprehensive introductory course, Essential Genetics: A Genomic Perspective, Fifth Edition includes carefully chosen topics that provide a solid foundation to the basic understanding of gene mutation, expression, and regulation. New and updated sections on genetic analysis, molecular genetics, probability in genetics, and pathogenicity islands ensure that students are kept up-to-date on current key topics. The text also provides students with a sense of the social and historical context in which genetics has developed. The updated companion web site provides numerous study tools, such as animated flashcards, crosswords, practice quizzes and more! New and expanded end-of-chapter material allows for a mastery of key genetics concepts and is ideal for homework assignments and in-class discussion.

The Human Genome

The Human Genome
A Book

by Julia E. Richards,R. Scott Hawley

  • Publisher : Academic Press
  • Release : 2010-12-12
  • Pages : 420
  • ISBN : 9780080918655
  • Language : En, Es, Fr & De
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Significant advances in our knowledge of genetics were made during the twentieth century but in the most recent decades, genetic research has dramatically increased its impact throughout society. Genetic issues are now playing a large role in health and public policy, and new knowledge in this field will continue to have significant implications for individuals and society. Written for the non-majors human genetics course, Human Genetics, 3E will increase the genetics knowledge of students who are learning about human genetics for the first time. This thorough revision of the best-selling Human Genome,2E includes entirely new chapters on forensics, stem cell biology, bioinformatics, and societal/ethical issues associated with the field. New special features boxes make connections between human genetics and human health and disease. Carefully crafted pedagogy includes chapter-opening case studies that set the stage for each chapter; concept statements interspersed throughout the chapter that keep first-time students focused on key concepts; and end-of-chapter questions and critical thinking activities. This new edition will contribute to creating a genetically literate student population that understands basic biological research, understands elements of the personal and health implications of genetics, and participates effectively in public policy issues involving genetic information . Includes topical material on forensics, disease studies, and the human genome project to engage non-specialist students Full, 4-color illustration program enhances and reinforces key concepts and themes Uniform organization of chapters includes interest boxes that focus on human health and disease, chapter-opening case studies, and concept statements to engage non-specialist readers

Vogel and Motulsky's Human Genetics

Vogel and Motulsky's Human Genetics
Problems and Approaches

by Michael Speicher,Stylianos E. Antonarakis,Arno G. Motulsky

  • Publisher : Springer Science & Business Media
  • Release : 2009-11-26
  • Pages : 981
  • ISBN : 3540376542
  • Language : En, Es, Fr & De
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The fourth edition of this classical reference book can once again be relied upon to present a cohesive and up-to-date exposition of all aspects of human and medical genetics. Human genetics has become one of the main basic sciences in medicine, and molecular genetics is increasingly becoming a major part of this field. This new edition integrates a wealth of new information - mainly describing the influence of the "molecular revolution" - including the principles of epigenetic processes which together create the phenotype of a human being. Other revisions are an improved layout, sub-division into a larger number of chapters, as well as two-colour print throughout for ease of reference, and many of the figures are now in full colour. For graduates and those already working in medical genetics.

Medical and Health Related Sciences Thesaurus

Medical and Health Related Sciences Thesaurus
A Book

by National Institutes of Health (U.S.)

  • Publisher : Unknown Publisher
  • Release : 1977
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Indexing terms used in CRISP (Computer Retrieval of Information on Scientific Projects) and in Research grants index. Alphabetical arrangement. Cross references under terms.

Genetics

Genetics
A Book

by Daniel L. Hartl,Maryellen Ruvolo

  • Publisher : Jones & Bartlett Publishers
  • Release : 2011-08-05
  • Pages : 800
  • ISBN : 1449626106
  • Language : En, Es, Fr & De
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The Eighth Edition of Genetics: Analysis of Genes and Genomes provides a clear, balanced, and comprehensive introduction to genetics and genomics at the college level. Expanding upon the key elements that have made this text a success, Hartl has included updates throughout, as well as a new chapter dedicated to genetic evolution. He continues to treat transmission genetics, molecular genetics, and evolutionary genetics as fully integrated subjects and provide students with an unprecedented understanding of the basic process of gene transmission, mutation, expression, and regulation. New chapter openers include a new section highlighting scientific competencies, while end-of-chapter Guide to Problem-Solving sections demonstrate the concepts needed to efficiently solve problems and understand the reasoning behind the correct answer. Important Notice: The digital edition of this book is missing some of the images or content found in the physical edition.