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Improving the Therapeutic Ratio in Head and Neck Cancer

Improving the Therapeutic Ratio in Head and Neck Cancer
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2019-10-04
  • Pages : 376
  • ISBN : 0128178698
  • Language : En, Es, Fr & De
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Improving the Therapeutic Ratio in Head and Neck Cancer provides a complete review of current approaches to modulating therapeutic sensitivity in head and neck cancer. It presents a broad background of current approaches and by highlighting the potential for clinical translational, introduces a roadmap for how to move promising preclinical findings into the clinic. The book discusses topics such as immunotherapy and molecularly targeted therapies in head and neck cancer, PI3k/mTOR pathway, autophagy inhibition to sensitize HNC to radiation and chemotherapy, TAM and Eph/Ephrin family proteins and metabolic reprogramming to modulate therapeutic sensitivity. Additionally, it details approaches to improve the response to immunotherapy, and Chk1/2 inhibition in radiation and cetuximab resistance. This book is a valuable source to head and neck cancer researchers and advanced students, and to those studying specific approaches in other model systems and disease sites. Provides key scientific background for clinicians when developing novel clinical trials and important examples for basic scientists of the types of work required to move a concept from the lab to the clinic Presents consistent pathway diagrams in each chapter, thus making it easier to understand complicated pathways Includes chapter summaries of the critical next steps needed to move studies from their current state into practice changing clinical data

Increasing the Therapeutic Ratio of Radiotherapy

Increasing the Therapeutic Ratio of Radiotherapy
A Book

by Philip J. Tofilon,Kevin Camphausen

  • Publisher : Springer
  • Release : 2016-11-21
  • Pages : 280
  • ISBN : 3319408542
  • Language : En, Es, Fr & De
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Current cancer therapies are focused on three general strategies: modifying intrinsic radiosensitivity via molecular targeting, manipulating microenvironmental factors to enhance tumor susceptibility to radiation, and improving delivery of radiation to critical tumor locations while sparing normal tissues. The goal of this volume is to describe a number of promising approaches corresponding to each strategy. In general, research in radiation oncology tends to be siloed into fundamental biology, physics or treatment delivery. The strategies for improving therapeutic ratio encompassed in this book will involve each of these components of radiation oncology. Thus, they will illustrate the variety of disparate approaches available for potentially improving the efficacy of radiotherapy, which may then stimulate discussion across disciplines and foster further translational investigations. Although a goal of each chapter will be to highlight advances within an approach, of equal importance will be the delineation of barriers to successful clinical application and how to overcome or minimize such impediments. Along these lines, because therapeutic ratio incorporates both tumor and normal tissue radio response, a point of emphasis will be the mechanistic rationale for selectively modifying tumor (sensitization) or normal cells (protection). Finally, whereas the literature is replete with studies describing potential targets/strategies for increasing the therapeutic ratio for radiotherapy, this book will focus on those supported by in vivo data consistent with impending translational application along with those that are already being evaluated in the clinic.

Head and Neck Cancer

Head and Neck Cancer
Proceedings of the International Conference, Baltimore, Maryland, July 22-27, 1984

by Paul B. Chretien

  • Publisher : Unknown Publisher
  • Release : 1985
  • Pages : 611
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Strategies to Enhance the Therapeutic Ratio of Radiation as a Cancer Treatment

Strategies to Enhance the Therapeutic Ratio of Radiation as a Cancer Treatment
A Book

by Mitchell S. Anscher,Kristoffer Valerie

  • Publisher : Springer
  • Release : 2016-10-20
  • Pages : 305
  • ISBN : 331945594X
  • Language : En, Es, Fr & De
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This volume will describe recent progress and future directions in radiation oncology and biology research, focusing on strategies designed to improve disease control and reduce the risk of long-term adverse effects on patients. As more and more patients are becoming long-term survivors, this strategy will become increasingly important--in radiation oncology and throughout the field of oncology.

International Journal of Radiation Oncology, Biology, Physics

International Journal of Radiation Oncology, Biology, Physics
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1986
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Cancer Research

Cancer Research
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1999
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Hyperthermic Oncology 1988

Hyperthermic Oncology 1988
A Book

by Tsutomu Sugahara,Masao Saito

  • Publisher : Taylor & Francis Group
  • Release : 1989
  • Pages : 950
  • ISBN : 9780850667929
  • Language : En, Es, Fr & De
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This two volume set forms the proceedings of the 5th International Symposium on Hyperthermic Oncology which was held in Kyoto, Japan, from 29 August to 3rd September 1988. The most recent developments in hyperthermic oncology are described and analyzed by leading researchers in the field.

Radiotherapy in Practice

Radiotherapy in Practice
External Beam Therapy

by Peter J. Hoskin

  • Publisher : Oxford University Press, USA
  • Release : 2006
  • Pages : 478
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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External beam therapy is used to aim highly focused beams of radiation at the edges of the site where cancer is found. The goal is to destroy any abnormal cells and prevent the growth or regrowth of the tumor. This book provides practical guidance on the use of External Beam Therapy, taking the reader through the basic principles covering indications, treatment, and planning, and then developing this by individual sites.

Excerpta Medica

Excerpta Medica
Cancer

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1991
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Management of Head and Neck Cancer

Management of Head and Neck Cancer
A Multidisciplinary Approach

by Rodney R. Million,Nicholas J. Cassisi

  • Publisher : Lippincott Williams & Wilkins
  • Release : 1994
  • Pages : 913
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Revised and updated, this edition provides a comprehensive, authoritative approach to head and neck cancer. Page after page is packed with clear and instructive illustrations - line drawings and halftones; fibre optic and microscopic examinations; CT scans; before and after treatment figures; plus many full-colour illustrations.

Current Opinion in Oncology

Current Opinion in Oncology
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1995
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Progress in Radio-oncology II

Progress in Radio-oncology II
A Book

by Karl-Heinz Kärcher,H. D. Kogelnik,G. Reinartz

  • Publisher : Raven Press (ID)
  • Release : 1962
  • Pages : 485
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Contemporary Issues in Oral Cancer

Contemporary Issues in Oral Cancer
A Book

by Dhananjaya Saranath

  • Publisher : Oxford University Press, USA
  • Release : 2000
  • Pages : 405
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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This book lays emphasis on various therapeutic approaches in head and neck cancers, including surgery, radiation therapy and photodynamic laser therapy. Other important topics discussed are the integration of surgery/radiation therapy with chemotherapy for better patient managemnet andfeasibility of immunotherapy and gene therapy in oral cancers, outlining the different therapeutic modalities. This book makes interesting reading for both biologists and doctors in research and clinical practice.

Virginia Medical

Virginia Medical
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1981
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Abstracts

Abstracts
A Book

by Anonim

  • Publisher : Pergamon
  • Release : 1979
  • Pages : 1072
  • ISBN : 9780080243788
  • Language : En, Es, Fr & De
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Volume 12.

Cancer in the Neck

Cancer in the Neck
Evaluation and Treatment

by David Lee Larson,Alando Jones Ballantyne,Oscar M. Guillamondegui

  • Publisher : Macmillan Publishing Company
  • Release : 1986
  • Pages : 280
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Hyperbaric Oxygen Review

Hyperbaric Oxygen Review
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1980
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Textbook of Hyperbaric Medicine

Textbook of Hyperbaric Medicine
A Book

by Kewal K. Jain

  • Publisher : Hogrefe & Huber Pub
  • Release : 2004
  • Pages : 536
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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This textbook covers hyperbaric medicine and the applications of hyperbaric oxygen (HBO) techniques. It explains the basic principles of HBO therapy, and its application in carbon monoxide poisoning and decompression sickness, as well as its use in numerous other areas.

The British Journal of Radiology

The British Journal of Radiology
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1993
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Cancer of the Head and Neck

Cancer of the Head and Neck
A Book

by Eugene N. Myers,James Y. Suen

  • Publisher : Unknown Publisher
  • Release : 1996
  • Pages : 964
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Under the superior editorship of Drs. Myers and Suen, over seventy leading authorities deliver the definitive, state-of-the-art source on head and neck cancer. This completely revised reference takes a multidisciplinary approach to the surgery and management of head and neck cancer patients.