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Inflammation, Advancing Age and Nutrition

Inflammation, Advancing Age and Nutrition
Research and Clinical Interventions

by Irfan Rahman,Debasis Bagchi

  • Publisher : Academic Press
  • Release : 2013-09-03
  • Pages : 394
  • ISBN : 0123978076
  • Language : En, Es, Fr & De
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The book provides a comprehensive overview to understanding the integrated impact of the concepts of cellular and molecular aspects, models, environmental factors, and lifestyle involved in premature aging. Additionally, it examines how functional food, dietary nutraceuticals or pharmacological compounds can reverse inflammation and premature aging based on personalized medicine. This book is a valuable resource for health professionals, scientists and researchers, nutritionists, health practitioners, students and for all those who wish to broaden their knowledge in the allied field. Includes models of aging, including worm, mouse and human Explores the relationship of inflammation with diseases, including ocular health, Alzheimer's and Parkinson's disease, and muscle health Encompasses a variety of lifestyle impacts, including diet, exercise and nutrition Includes suggested nutritional interventions

AUTOIMMUNE DIET AND RECOVERY PLAN

AUTOIMMUNE DIET AND RECOVERY PLAN
A Simple Guide to Autoimmune Disease, How to Know if You Are at Risk and How to Treat it

by Jennifer Michaels

  • Publisher : Speedy Publishing LLC
  • Release : 2013-12-30
  • Pages : 37
  • ISBN : 1630226831
  • Language : En, Es, Fr & De
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Are you at risk for autoimmune disease? Do you feel frequently tired, irritable or under the weather? Are you experiencing achiness, brain fog or weight problems? Then it's time to take action. Has your doctor recently told you that an autoimmune test, such as a test for antinuclear antibodies (ANA), is equivocal, borderline, or positive? If so, you are at risk for autoimmune disease. Like an automobile that needs coolant and an oil change, this is the time to take action--fast! The AUTOIMMUNE DIET AND RECOVERY PLAN offers the information you're looking for, now. Traditional allopathic physicians offer powerful pharmaceutical therapies that can address some of the issues relating to an overly active immune system, but at a very great cost. These therapies, by depressing the immune system, do not treat the root cause of your problem and also increase the chances of contracting even more serious ailments, like cancer, by up to 400 hundred times. This book shares an up?to?date summary of research and available, natural treatments and therapies to use today.

Immunity and Inflammation in Health and Disease

Immunity and Inflammation in Health and Disease
Emerging Roles of Nutraceuticals and Functional Foods in Immune Support

by Shampa Chatterjee,Wolfgang Jungraithmayr,Debasis Bagchi

  • Publisher : Academic Press
  • Release : 2017-08-31
  • Pages : 476
  • ISBN : 0128054026
  • Language : En, Es, Fr & De
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Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support provides a comprehensive description of the various pathways by which the vertebrate immune system works, the signals that trigger immune response and how fnew and novel nutraceuticals and functional foods, can be used to contain inflammation and also to boost immunity and immune health. Inflammation is a tool to fight pathogens and the vertebrate immune system has a very complex network of cells to achieve this. However inflammation that goes awry is also the leding cause of several diseases ranging from cardiovascular diseases to diabetes. This book covers the entire gamut from the various cellular players in the inflammation-immune response to its ramifications in terms of protection against pathogens as well as in onset of metabolic, aging and auto-immune related diseases. Finally, the balancing role of dietary nutrients between host defence and immune support is also showcased. The first three scetions explain the various components of the immune system and their modes of activation. The fourth section deals with the ramifications of a robust and execessive inflammatory response. The fifth section is focused on the association between nutrition and immunity and how deficiencies in certain nutrients may affect immunocompetence. The sixth section chapters represent a vision of paradigm shifts within the field and discusses possible future directions. This bool will be a valuable reference for researchers studying immune health either in academia, or in the nutraceutical or functional food industries. Product developers in nutraceutical, supplement, functional food, and health food companies will also appreciate the information presented here. Conceptualizes the key features in natural products which can boost immune function and immune health Explains the intricate mechanistic aspects and balance behind immune health Presents the pathophysiology of several diseases associated with immune system disruption

Food as Medicine

Food as Medicine
Functional Food Plants of Africa

by Maurice M. Iwu

  • Publisher : CRC Press
  • Release : 2016-11-25
  • Pages : 384
  • ISBN : 1315354381
  • Language : En, Es, Fr & De
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This comprehensive book documents African plants used for functional and medicinal foods. It contains more than 60 detailed monographs of African foods, describing foods with various characteristics such as prebiotic, probiotic, satiety, immune modulation, stress-reduction, sports performance, mental acuity, sleep-supporting, metabolic syndrome, antioxidant, and unsaturated fats. Plant description, botanical names and synonyms, plant part used, habitat and distribution, folk use, nutritional content, and chemistry are all fully detailed. The book highlights indigenous African food processing technologies up to the modern era.

Epigenetics of Aging and Longevity

Epigenetics of Aging and Longevity
Translational Epigenetics

by Alexey Moskalev,Alexander M. Vaiserman

  • Publisher : Academic Press
  • Release : 2017-11-17
  • Pages : 544
  • ISBN : 012811083X
  • Language : En, Es, Fr & De
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Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in regulating specific age-associated illnesses—including cancer and cardiovascular, metabolic, and neurodegenerative diseases—are explored in detail. This book will help researchers in genomic medicine, epigenetics, and biogerontology better understand the epigenetic determinants of aging and longevity, and ultimately aid in developing therapeutics to extend the human life-span and treat age-related disease. Offers a comprehensive overview of the epigenetic nature of aging, as well as the impact of epigenetic factors on longevity and regulating age-related disease Provides readers with clinical and epidemiological evidence for the role of epigenetic mechanisms in mediating the link between early-life experiences, life-course health and aging trajectory Applies current knowledge of epigenetic regulatory pathways towards developing therapeutic interventions for age-related diseases and extending the human lifespan

Molecular Basis and Emerging Strategies for Anti-aging Interventions

Molecular Basis and Emerging Strategies for Anti-aging Interventions
A Book

by Syed Ibrahim Rizvi,Ufuk Çakatay

  • Publisher : Springer
  • Release : 2018-11-02
  • Pages : 386
  • ISBN : 9811316996
  • Language : En, Es, Fr & De
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This book describes the nature of aging, age-related disorders, and the molecular principles of emerging strategies for anti-aging interventions, while also discussing the discovery of targets for geroprotective drugs. Although significant medical advances in the treatment and eradication of life-threatening conditions such as cardiovascular and infectious disease have been made over the past five decades, the prevalence of age-related disorders still remains high in older populations. Intervening into aging is the next frontier in contemporary medicine, and will be of increasing importance over time, as other sources of poor health are combated more and more successfully. Given the universal interest in anti-aging strategies, the book will appeal to a very broad audience. It addresses a diverse range of anti-aging interventions – including stem cells, autophagy, senolytics, anti-inflammatory methods, and telomerase induction – that will be of interest to scientists and researchers from various disciplines in the life sciences.

Allogeneic Mesenchymal Stem Cells as a Treatment for Aging Frailty

Allogeneic Mesenchymal Stem Cells as a Treatment for Aging Frailty
A Book

by Bryon A. Tompkins

  • Publisher : Unknown Publisher
  • Release : 2017
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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As life expectancy is projected to increase in the ensuing decades, individuals of older age continue to exceed the previous generation's lifespan. Advancing age is associated with a reduction in physical and mental functional capacity, and chronic inflammation is a major factor contributing to this decline. A heightened inflammatory state can lead to exhaustion, weakness, weight loss, slow gate speed, and an overall decrease in activity level. These phenotypes define the onset of the disease process known as frailty. Frailty is a growing epidemic, which severely undermines a person's ability to deal with outside stressors, and increases their rate of hospitalization, institutionalization, and mortality. Current interventions focus on preventative care by improving exercise capacity, strength, nutritional supplementation, diet, and mobility. However, a biological cure has heretofore remained elusive. Here, we introduce the novel therapeutic principle that mesenchymal stem cell (MSC) therapy may represent a safe, practical, and efficacious both the treatment and prevention of frailty in individuals of advancing age. To date, a phase I safety trial reveals an excellent safety profile and suggests that mesenchymal stem cells can ameliorate signs and symptoms of frailty. These early studies lay the groundwork for future large-scale clinical trials of this exciting and novel therapeutic concept that has the potential to expand health span in the aging population.

Biomaterials in Regenerative Medicine and the Immune System

Biomaterials in Regenerative Medicine and the Immune System
A Book

by Laura Santambrogio

  • Publisher : Springer
  • Release : 2015-09-04
  • Pages : 280
  • ISBN : 3319180452
  • Language : En, Es, Fr & De
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The generation of tridimensional tissues, assembled from scaffolding materials populated with biologically functional cells, is the great challenge and hope of tissue bioengineering and regenerative medicine. The generation of biomaterials capable of harnessing the immune system has been particularly successful. This book provides a comprehensive view of how immune cells can be manipulated to suppresses inflammation, deliver vaccines, fight cancer cells, promote tissue regeneration or inhibit blood clotting and bacterial infections by functionally engineered biomaterials. However, long-lived polymers, such as those employed in orthopedic surgery or vascular stents, can often induce an immune reaction to their basic components. As a result, this book is also an important step towards coming to understand how to manipulate biomaterials to optimize their beneficial effects and downplay detrimental immune responses.

Biotechnology

Biotechnology
A Book

by David P. Clark,Nanette J. Pazdernik

  • Publisher : Newnes
  • Release : 2015-05-16
  • Pages : 850
  • ISBN : 0123850169
  • Language : En, Es, Fr & De
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Biotechnology, Second Edition approaches modern biotechnology from a molecular basis, which has grown out of increasing biochemical understanding of genetics and physiology. Using straightforward, less-technical jargon, Clark and Pazdernik introduce each chapter with basic concepts that develop into more specific and detailed applications. This up-to-date text covers a wide realm of topics including forensics, bioethics, and nanobiotechnology using colorful illustrations and concise applications. In addition, the book integrates recent, relevant primary research articles for each chapter, which are presented on an accompanying website. The articles demonstrate key concepts or applications of the concepts presented in the chapter, which allows the reader to see how the foundational knowledge in this textbook bridges into primary research. This book helps readers understand what molecular biotechnology actually is as a scientific discipline, how research in this area is conducted, and how this technology may impact the future. Up-to-date text focuses on modern biotechnology with a molecular foundation Includes clear, color illustrations of key topics and concept Features clearly written without overly technical jargon or complicated examples Provides a comprehensive supplements package with an easy-to-use study guide, full primary research articles that demonstrate how research is conducted, and instructor-only resources

The Science of Hormesis in Health and Longevity

The Science of Hormesis in Health and Longevity
A Book

by Suresh I. S. Rattan,Marios Kyriazi

  • Publisher : Academic Press
  • Release : 2018-10-23
  • Pages : 326
  • ISBN : 0128142545
  • Language : En, Es, Fr & De
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The Science of Hormesis in Health and Longevity provides a comprehensive review of mild stress-induced physiological hormesis and its role in the maintenance and promotion of health. Coverage includes the underlying mechanisms of hormesis, including details of stress-response signaling, an enriched environment, positive challenges and dose-response mechanisms, amongst others. Research from top experts is presented to provide suggestions for developing novel therapeutic strategies, along with lifestyle interventions to promote health and homoeostasis. Researchers in aging and physiology, gerontologists, clinicians and medical students will find this a valuable addition for their work. Provides a comprehensive, scholarly review of the current state of hormesis in physiology, health, disease and aging Includes multiple perspectives and in-depth analysis by top experts involved in cutting-edge research to provide developing, novel therapeutic strategies, as well as lifestyle interventions Offers a clear understanding of hormesis’ underlying mechanisms, including details of stress-response signaling, an enriched environment, positive challenges, dose-response mechanisms, and more

Nutrition for the Middle Aged and Elderly

Nutrition for the Middle Aged and Elderly
A Book

by Nancy E. Bernhardt,Artur M. Kasko

  • Publisher : Nova Publishers
  • Release : 2008
  • Pages : 492
  • ISBN : 9781604561463
  • Language : En, Es, Fr & De
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The ageing process changes body composition and thus nutritional status changes as one gets older. At the same time the body becomes more susceptible to diseases and diet becomes an even more significant or at least visibly significant than in earlier years. Moreover, there is frequently socio-economic downward drifting in this age group making nutritious foods more difficult to afford. This book presents the latest research in this vital field.

Muscle and Exercise Physiology

Muscle and Exercise Physiology
A Book

by Jerzy A. Zoladz

  • Publisher : Academic Press
  • Release : 2018-11-05
  • Pages : 618
  • ISBN : 0128145943
  • Language : En, Es, Fr & De
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Muscle and Exercise Physiology is a comprehensive reference covering muscle and exercise physiology, from basic science to advanced knowledge, including muscle power generating capabilities, muscle energetics, fatigue, aging and the cardio-respiratory system in exercise performance. Topics presented include the clinical importance of body responses to physical exercise, including its impact on oxygen species production, body immune system, lipid and carbohydrate metabolism, cardiac energetics and its functional reserves, and the health-related effects of physical activity and inactivity. Novel topics like critical power, ROS and muscle, and heart muscle physiology are explored. This book is ideal for researchers and scientists interested in muscle and exercise physiology, as well as students in the biological sciences, including medicine, human movements and sport sciences. Contains basic and state-of-the-art knowledge on the most important issues of muscle and exercise physiology, including muscle and body adaptation to physical training, the impact of aging and physical activity/inactivity Provides both the basic and advanced knowledge required to understand mechanisms that limit physical capacity in both untrained people and top class athletes Covers advanced content on muscle power generating capabilities, muscle energetics, fatigue and aging

Antioxidants and Functional Foods for Neurodegenerative Disorders

Antioxidants and Functional Foods for Neurodegenerative Disorders
Uses in Prevention and Therapy

by Abhai Kumar,Debasis Bagchi

  • Publisher : CRC Press
  • Release : 2021-01-08
  • Pages : 454
  • ISBN : 1000282740
  • Language : En, Es, Fr & De
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Neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, are a growing problem across the world’s aging population. Oxidative stress in the brain plays a central role in a common pathophysiology of these diseases. This book presents scientific research on the potential of antioxidant therapy in the prevention and treatment of neurodegenerative disorders. This book outlines the roles of oxidative stress and diabetes mellitus in neurodegeneration, describes the molecular mechanisms of neurodegenerative disorders including the roles of environmental pollutants and inflammatory responses, and explores mitochondrial dysfunction. It then describes the protective abilities of antioxidants – including vitamin D, tocotrienol and coenzyme Q10 – against neurodegeneration. The book demonstrates the therapeutic potential of ketogenic diets, and highlights the roles of medicinal plants, phytopharmaceuticals, traditional medicines and food nutrients in neuroprotection. Key Features: Explains damage caused by numerous neurodegenerative disorders and the possible protection offered by antioxidants and functional foods. Describes molecular mechanisms of neurodegeneration by oxidative stress, advancing age, diabetes and mitochondrial dysfunctions. Demonstrates protection offered by nutraceuticals, antioxidants, botanical extracts and functional foods. The book contains twenty-three chapters divided into six sections written by leading researchers. This book is essential reading for health professionals, dietitians, food and nutrition scientists and anyone wanting to improve their knowledge of etiology of neurodegenerative diseases.

Frailty: Pathophysiology, Phenotype and Patient Care

Frailty: Pathophysiology, Phenotype and Patient Care
83rd Nestlé Nutrition Institute Workshop, Barcelona, March 2014

by R.A. Fielding,C. Sieber,B. Vellas

  • Publisher : Karger Medical and Scientific Publishers
  • Release : 2015-10-26
  • Pages : 108
  • ISBN : 331805478X
  • Language : En, Es, Fr & De
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The demographic shift in the average age of the population worldwide calls for careful attention to the nutritional and health needs of the elderly. Frailty has been associated with increased disability, postsurgical complications and increased mortality; in a frail state, older adults are at greater risk for adverse outcomes, including falls and admissions to hospital and nursing homes. Despite the strong associations between frailty and subsequent poor outcomes, limited attention to this common geriatric condition has been paid in clinical settings. Emerging evidence suggests that both behavioral (nutrition and physical activity) and pharmacologic interventions may be effective in the treatment and prevention of the frailty syndrome. The papers in this book address our current understanding of the biological basis, clinical presentation and therapeutic interventions that target frailty. They highlight the transitional nature of research on the frailty syndrome and identified key unmet needs and areas for future investigation in this expanding field.

Exercise as a Countermeasure to Human Aging

Exercise as a Countermeasure to Human Aging
A Book

by Bradley Elliott,Lawrence D. Hayes,David C. Hughes,Martin Burtscher

  • Publisher : Frontiers Media SA
  • Release : 2020-11-12
  • Pages : 329
  • ISBN : 2889660109
  • Language : En, Es, Fr & De
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Recent Advances in Immunology to Target Cancer, Inflammation and Infections

Recent Advances in Immunology to Target Cancer, Inflammation and Infections
A Book

by Jagat Kanwar

  • Publisher : BoD – Books on Demand
  • Release : 2012-05-09
  • Pages : 534
  • ISBN : 9535105922
  • Language : En, Es, Fr & De
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Immunology is the branch of biomedical sciences to study of the immune system physiology both in healthy and diseased states. Some aspects of autoimmunity draws our attention to the fact that it is not always associated with pathology. For instance, autoimmune reactions are highly useful in clearing off the excess, unwanted or aged tissues from the body. Also, generation of autoimmunity occurs after the exposure to the non-self antigen that is structurally similar to the self, aided by the stimulatory molecules like the cytokines. Thus, a narrow margin differentiates immunity from auto-immunity as already discussed. Hence, finding answers for how the physiologic immunity turns to pathologic autoimmunity always remains a question of intense interest. However, this margin could be cut down only if the physiology of the immune system is better understood. The individual chapters included in this book will cover all the possible aspects of immunology and pathologies associated with it. The authors have taken strenuous effort in elaborating the concepts that are lucid and will be of reader's interest.

Nutrition and Bone Health

Nutrition and Bone Health
A Book

by Michael F. Holick,Jeri W. Nieves

  • Publisher : Springer
  • Release : 2014-12-13
  • Pages : 718
  • ISBN : 1493920014
  • Language : En, Es, Fr & De
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This newly revised edition contains updated versions of all of the topics that were in the first edition and has been substantially expanded with an additional 5 chapters. Each chapter includes information from the most up-to-date research on how nutritional factors can affect bone health, written with an evidence-based focus and complete with comprehensive references for each subject. Nutrition and Bone Health, second edition covers all aspects of nutrition and the skeleton, from the history and fundamentals, to the effects of macronutrients, minerals, vitamins, and supplements, and even covers the effects of lifestyle, the different life stages, and nutrition-related disorders and secondary osteoporosis. New chapters include HIV & AIDs and the skeleton, celiac disease and bone health, and nutrition and bone health in space. Nutrition and Bone Health, second edition is a necessary resource for health care professionals, medical students, graduate students, dietitians, and nutritionists who are interested in how nutrition affects bone health during all stages of life.

Practical Aspects of Nutritional Support

Practical Aspects of Nutritional Support
An Advanced Practice Guide

by Patricia H. Worthington

  • Publisher : W B Saunders Company
  • Release : 2004
  • Pages : 608
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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This portable, practical reference is designed to fill the need for primary care and clinical nutrition information for nurse practitioners within various specialty areas such as adult, family, pediatric, and acute care. It addresses the fundamentals of nutritional care including nutritional assessment, identifying risk factors, determining nutrient requirements, and selecting appropriate intervention. Life cycle nutrition, functional elements of nutrition support, pharmacologic considerations, trends in nutritional care, and nutritional considerations in specific disease states are also covered. Reflects the commitment to an interdisciplinary approach to patient care through the contributors' expertise in a variety of disciplines. Addresses the needs of patients throughout the life cycle and in a variety of health care settings. Covers age-appropriate interventions and explores the cultural and ethnic considerations that take on greater significance as the US population grows increasingly diverse. Addresses techniques and procedures such as safely feeding patients with dysphasia, inserting and maintaining enteral access devices, care of vascular access devices, monitoring response to therapy, and troubleshooting and preventing complications. Provides information on drug-nutrient interactions, pharmacological issues related to parenteral nutrition, and non-traditional approaches to therapeutic nutrition. Covers nutritional implications of selected disease states and provides evidence-based guidelines for nutritional management of medical conditions in which nutritional intervention plays a prominent role. The user-friendly format features charts, tables, and bulleted lists that provide quick, easy access to information. A list of Internet Resources at the end of each chapter direct clinicians to websites for more in-depth information, sources for educational material, and support groups for patients.

Integrated Role of Nutrition and Physical Activity for Lifelong Health

Integrated Role of Nutrition and Physical Activity for Lifelong Health
A Book

by Karsten Koehler,Clemens Drenowatz

  • Publisher : MDPI
  • Release : 2019-07-16
  • Pages : 202
  • ISBN : 3039212117
  • Language : En, Es, Fr & De
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As computer and space technologies have been developed, geoscience information systems (GIS) and remote sensing (RS) technologies, which deal with the geospatial information, have been rapidly maturing. Moreover, over the last few decades, machine learning techniques including artificial neural network (ANN), deep learning, decision tree, and support vector machine (SVM) have been successfully applied to geospatial science and engineering research fields. The machine learning techniques have been widely applied to GIS and RS research fields and have recently produced valuable results in the areas of geoscience, environment, natural hazards, and natural resources. This book is a collection representing novel contributions detailing machine learning techniques as applied to geoscience information systems and remote sensing.

Conn's Handbook of Models for Human Aging

Conn's Handbook of Models for Human Aging
A Book

by Jeffrey L. Ram,P. Michael Conn

  • Publisher : Academic Press
  • Release : 2018-04-05
  • Pages : 1218
  • ISBN : 0128113545
  • Language : En, Es, Fr & De
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Conn's Handbook of Models for Human Aging, Second Edition, presents key aspects of biology, nutrition, factors affecting lifespan, methods of age determination, use in research and the disadvantages/advantages of use. Using a multidisciplinary approach, this updated edition is designed as the only comprehensive, current work that covers the diversity in aging models. Chapters on comparative models explore age-related diseases, including Alzheimer's, joint disease, cataracts, cancer and obesity. Also included are new tricks and approaches not available in primary publications. This must-have handbook is an indispensable resource for researchers interested in the mechanisms of aging, gerontologists, health professionals, allied health practitioners and students. Combines both the methods of study for human aging and animal models Provides a historical overview and discussion of model availability, key methods and ethical issues Contains over 200 full color illustrations