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Inhaled Medicines

Inhaled Medicines
Optimizing Development through Integration of In Silico, In Vitro and In Vivo Approaches

by Stavros Kassinos,Per Bäckman,Joy Conway,Anthony J. J. Hickey

  • Publisher : Academic Press
  • Release : 2021-01-20
  • Pages : 438
  • ISBN : 0128149752
  • Language : En, Es, Fr & De
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Inhaled medicines are widely used to treat pulmonary and systemic diseases. The efficacy and safety of these medicines can be influenced by the deposited fraction, the regional deposition pattern within the lungs and by post-depositional events such as drug dissolution, absorption and clearance from the lungs. Optimizing performance of treatments thus requires that we understand and are able to quantify these product and drug attributes. Inhaled Medicines: Optimizing Development through Integration of In Silico, In Vitro and In Vivo Approaches explores the current state of the art with respect to inhalation drug delivery, technologies available to assess product performance, and novel in silico methods now available to link in vitro product performance to clinical performance. Recent developments in the latter field, especially the prospect of integration of three-dimensional Computational Fluid Particle Methods (3D-CFPD) with physiologically based pharmacokinetic (PBPK models), unlocks the potential for in silico population studies that can help inform and optimize treatment and product development strategies. In this highly multidisciplinary field, where progress occurs at the intersection of several disciplines of engineering and science, this work aims to integrate current knowledge and understanding and to articulate a clear vision for future developments. ● Considers the healthcare needs driving the field, and where inhaled drugs could have the maximum impact ● Gives a concise account of the state of the art in key areas and technologies such as device and formulation technologies, clinically relevant in vitro performance assessment, medical imaging, as well as in silico modelling and simulation ● Articulates how the combination of in vitro product performance data, medical imaging and simulations technologies in the framework of large scale in silico pre-clinical trials could revolutionize the field ● Provides systematic and thorough referencing to sources offering a more-in-depth analysis of technical issues

Cases illustrative of the efficacy of various medicines administered by inhalation, in preliminary consumption; in certain morbid states of the trachea and bronchial tubes, attended with distressing cough, and in asthma

Cases illustrative of the efficacy of various medicines administered by inhalation, in preliminary consumption; in certain morbid states of the trachea and bronchial tubes, attended with distressing cough, and in asthma
A Book

by Sir Charles SCUDAMORE

  • Publisher : Unknown Publisher
  • Release : 1830
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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American Journal of Respiratory and Critical Care Medicine

American Journal of Respiratory and Critical Care Medicine
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2005
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Pharmacology and Medicines Management for Nurses

Pharmacology and Medicines Management for Nurses
A Book

by George Downie (MSc.),Jean Mackenzie (RGN.),Arthur Williams (MPS.),Caroline Hind

  • Publisher : Churchill Livingstone
  • Release : 2008
  • Pages : 568
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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This edition has been fully updated and now includes self-assessment exercises with answers.

A Dictionary of Medicine

A Dictionary of Medicine
Including General Pathology, General Therapeutics, ...

by Richard Quain

  • Publisher : Unknown Publisher
  • Release : 1883
  • Pages : 1816
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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A Dictionary of Medicine

A Dictionary of Medicine
Including General Pathology, General Therapeutics, Hygiene ...

by Sir Richard Quain,John Mitchell Bruce,Frederick Thomas Roberts

  • Publisher : Unknown Publisher
  • Release : 1884
  • Pages : 1816
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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A Dictionary of Medicine Including General Pathology, General Therapeutics, Hygiene, and the Diseases Peculiar to Women and Children

A Dictionary of Medicine Including General Pathology, General Therapeutics, Hygiene, and the Diseases Peculiar to Women and Children
A Book

by Sir Richard Quain (bart.)

  • Publisher : Unknown Publisher
  • Release : 1884
  • Pages : 1816
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The Mechanics of Inhaled Pharmaceutical Aerosols

The Mechanics of Inhaled Pharmaceutical Aerosols
An Introduction

by Warren H. Finlay

  • Publisher : Academic Press
  • Release : 2019-06-01
  • Pages : 302
  • ISBN : 0081027869
  • Language : En, Es, Fr & De
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The Mechanics of Inhaled Pharmaceutical Aerosols: An Introduction, Second Edition provides a concise, but thorough exposition of fundamental concepts in the field of pharmaceutical aerosols. This revised edition will allow researchers in the field to gain a thorough understanding of the field from first principles, allowing them to understand, design, develop and improve inhaled pharmaceutical aerosol devices and therapies. Chapters consider mechanics and deposition, specifically in the respiratory tract, while others discuss the mechanics associated with the three existing types of pharmaceutical inhalation devices. This text will be very useful for academics and for courses taught at both undergraduate and graduate levels. Because of the interdisciplinary nature of this book, it will also serve a wide audience that includes engineers and scientists involved with inhaled aerosol therapies. Provides a concise, but thorough exposition of fundamental concepts in the field of pharmaceutical aerosols Allows researchers in the field to gain an up-to-date, thorough understanding of the field from first principles Introduces the pharmaceutical aerosols field to the many engineers and scientists entering the area

Asthma Sourcebook

Asthma Sourcebook
Basic Consumer Health Information about the Causes, Symptoms, Diagnosis, and Treatment of Asthma in Infants, Children, Teenagers, and Adults ...

by Karen Bellenir

  • Publisher : Omnigraphics Incorporated
  • Release : 2006
  • Pages : 609
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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"Provides basic consumer health information about causes, triggers, treatment, and management of asthma. Includes index, glossary of related terms, and other resources"--Provided by publisher.

Asthma Information for Teens

Asthma Information for Teens
Health Tips about Managing Asthma and Related Concerns Including Facts about Asthma Causes, Triggers, Symptoms, Diagnosis, and Treatment

by Karen Bellenir

  • Publisher : Omnigraphics Incorporated
  • Release : 2005
  • Pages : 386
  • ISBN : 9780780807709
  • Language : En, Es, Fr & De
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Including Facts about Asthma Causes, Triggers, Symptoms, Diagnosis, and Treatment.

Emergency Medicine

Emergency Medicine
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2002
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Consumer Drug Reference 2005

Consumer Drug Reference 2005
A Book

by Thompson Healt Micromedex

  • Publisher : Unknown Publisher
  • Release : 2004
  • Pages : 1736
  • ISBN : 9780890439937
  • Language : En, Es, Fr & De
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Accompanied by a color chart that helps identify the most common pills and tablets, a comprehensive and practical reference to more than eleven thousand prescription drugs, non-prescription medicines, and nutritional supplements covers side effects, indications, proper usage, interactions with other food and other drugs, dosage information, and much more. 25,000 first printing.

Innovation in the Pharmaceutical Industry

Innovation in the Pharmaceutical Industry
The Process of Drug Discovery and Development

by Takuji Hara

  • Publisher : Edward Elgar Publishing
  • Release : 2003
  • Pages : 271
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Innovation in the Pharmaceutical Industry traces the discovery and development of drugs in Japan and the UK both historically and sociologically. It includes sixteen case studies of major pharmaceutical developments in the twentieth century, encompassing, amongst others, beta-blockers, beta-stimulants, inhaled steroids and histamine H2-antagonists.The book illustrates that the four stages of drug development - namely compound, application, organisational authorisation and market - are interactively shaped by heterogeneous actors and institutions. The book also identifies three different types of pharmaceutical development - paradigmatic innovation, application innovation and modification-based innovation, all with distinguishable features in the drug development process. Finally, several historical, structural and cultural factors influencing the shaping of medicines are revealed by the comparison between British and Japanese drug innovation.Addressing a number of practical implications for the promotion of the pharmaceutical industry, this book will be of enormous interest to students, researchers and academics specialising in science and technology, and the management of technology and innovation. Practitioners, managers, and policy planners within the pharmaceutical industry will also deem this book invaluable.

Nursing Times, Nursing Mirror

Nursing Times, Nursing Mirror
NT

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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American Medical Women's Association Guide to Ears, Nose, and Throat

American Medical Women's Association Guide to Ears, Nose, and Throat
A Book

by Roselyn Payne Epps,American Medical Women's Association

  • Publisher : Dell
  • Release : 1996
  • Pages : 210
  • ISBN : 9780440223115
  • Language : En, Es, Fr & De
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An authoritative and comprehensive guide to the problems of the ears, nose, and throat, furnishes information on prevention, treatment, and cures of infection, allergies, and other disorders. Original.

Complete Drug Reference 1995

Complete Drug Reference 1995
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1994-11
  • Pages : 1760
  • ISBN : 9780890437698
  • Language : En, Es, Fr & De
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A comprehensive guide provides unbiased information for more than nine thousand brand name and generic drugs, explaining their proper usage, counteractions with foods and other drugs, possible side effects, precautions for pregnant women, and more.

Davidson's Principles and Practice of Medicine

Davidson's Principles and Practice of Medicine
A Book

by Sir Stanley Davidson

  • Publisher : W.B. Saunders Company
  • Release : 1995
  • Pages : 1203
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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This text on clinical medicine has been updated to aid learning and revision. Topics covered include genetic, climatic and environmental factors in disease, and endocrine and metabolic diseases, whilst a new chapter on geriatric medicine has also been included. An ELBS/LPBB edition is available.

Exam Prep for: The Mechanics of Inhaled Pharmaceutical Aerosols

Exam Prep for: The Mechanics of Inhaled Pharmaceutical Aerosols
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2021
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Hospital Medicine

Hospital Medicine
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1998
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Understanding Canadian Prescription Drugs : a Consumer's Guide to Correct Use

Understanding Canadian Prescription Drugs : a Consumer's Guide to Correct Use
A Book

by Dorothy L. Smith,Association pharmaceutique canadienne

  • Publisher : Unknown Publisher
  • Release : 1989
  • Pages : 389
  • ISBN : 9781550131291
  • Language : En, Es, Fr & De
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