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Laboratory Exercises in Molecular Pathology

Laboratory Exercises in Molecular Pathology
A Book

by Jonathon W. Homeister,Gregory J. Tsongalis,William B. Coleman

  • Publisher : Academic Press
  • Release : 2017-10-01
  • Pages : 400
  • ISBN : 9780128006085
  • Language : En, Es, Fr & De
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Laboratory Exercises in Molecular Pathology is organized by major organ systems and then by disease type. In each exercise, there is a distillation of essential disease-specific information (related to frequency, risk factors, disease manifestations) and a description of disease pathogenesis (molecular and cellular) that is based upon accepted principles from the literature. Further, each exercise is illustrated with (1) gross specimens, (2) microscopic histopathology, (3) immunohistochemistry and/or in situ hybridization (when applicable), (4) laboratory techniques to probe the molecular nature of the pathological lesions, and (5) molecular diagnostics (when applicable). In addition, each exercise contains one or more cases studies to provide students with exposure to the clinical workup of a patient, based upon physical examination findings, traditional pathological analysis, and state-of-the-art molecular assessment. The laboratory techniques included emphasize the dissection of molecular and cellular pathogenesis of the disease in question. Hence, students will see examples of laboratory results that illustrate how pathways were elucidated. Further, the sections on molecular diagnostics illustrate how molecular testing exploits what is known about molecular pathogenesis in a specific disease setting. The manual does not present molecular methods and techniques in isolation; it illustrates how these experimental approaches and applied methodologies can be used to generate meaningful information in the clinical setting. Presents foundational information, examples of gross and microscopic pathology, and examples of molecular approaches and molecular testing all in one resource Offers an ancillary website with videos corresponding to the evaluation of gross specimens, the assessment of microscopic images, and the demonstration of how laboratory techniques are performed Features exercises which contain one or more cases studies to provide students with exposure to the clinical workup of a patient, based upon physical examination findings, traditional pathological analysis, and state-of-the-art molecular assessment Provides case studies which include self-assessment modules and decision trees that allow students to make mistakes and then receive explanations

Diagnostic Molecular Pathology

Diagnostic Molecular Pathology
A Guide to Applied Molecular Testing

by William B. Coleman,Gregory J. Tsongalis

  • Publisher : Academic Press
  • Release : 2016-10-05
  • Pages : 582
  • ISBN : 0128011572
  • Language : En, Es, Fr & De
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Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). In each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms. Sections are dedicated to general methodologies employed in testing (to convey the concepts reflected in the methods), and specific description of how these methods can be applied and are applied to specific diseases are described. The book does not present molecular methods in isolation, but considers how other evidence (symptoms, radiology or other imaging, or other clinical tests) is used to guide the selection of molecular tests or how these other data are used in conjunction with molecular tests to make diagnoses (or otherwise contribute to clinical workup). In addition, final chapters look to the future (new technologies, new approaches) of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests. Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing contains exercises to test readers on their understanding of how molecular diagnostic tests are utilized and the value of the information that can be obtained in the context of the patient workup. Readers are directed to an ancillary website that contains supplementary materials in the form of exercises where decision trees can be employed to simulate actual clinical decisions. Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis, and classification in the clinical workup of a patient Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for prognostication of disease Features an ancillary website with self-testing exercises where decision trees can be employed to simulate actual clinical decisions Highlights new technologies and approaches of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests

Plant Pathology Concepts and Laboratory Exercises

Plant Pathology Concepts and Laboratory Exercises
A Book

by Bonnie H. Ownley,Robert N. Trigiano

  • Publisher : CRC Press
  • Release : 2016-11-03
  • Pages : 582
  • ISBN : 1498774725
  • Language : En, Es, Fr & De
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Continuing in the tradition of its predecessors, this new edition combines an informal, easy to read style with a thorough introduction to concepts and terminology of plant pathology. After reviewing fundamental concepts, the book discusses groups of plant pathogens and molecular tools for studying them, pathogen interactions, epidemiology and disease control, and special topics in plant pathology. The book details various disease-causing organisms, including viruses, fungi, prokaryotics, nematodes, and various biotic agents. It also examines various plant-pathogen interactions, molecular attack strategies, extracellular enzymes, host defenses, and disruption of plant function. New in the Third Edition Molecular plant-fungal interactions Expanded treatment of molecular tools Advanced biocontrol concepts How to use and care for microscopes

Molecular Diagnostics

Molecular Diagnostics
A Book

by George P. Patrinos,Wilhelm Ansorge,Phillip B. Danielson

  • Publisher : Academic Press
  • Release : 2016-10-27
  • Pages : 520
  • ISBN : 0128029889
  • Language : En, Es, Fr & De
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Molecular Diagnostics, Third Edition, focuses on the technologies and applications that professionals need to work in, develop, and manage a clinical diagnostic laboratory. Each chapter contains an expert introduction to each subject that is next to technical details and many applications for molecular genetic testing that can be found in comprehensive reference lists at the end of each chapter. Contents are divided into three parts, technologies, application of those technologies, and related issues. The first part is dedicated to the battery of the most widely used molecular pathology techniques. New chapters have been added, including the various new technologies involved in next-generation sequencing (mutation detection, gene expression, etc.), mass spectrometry, and protein-specific methodologies. All revised chapters have been completely updated, to include not only technology innovations, but also novel diagnostic applications. As with previous editions, each of the chapters in this section includes a brief description of the technique followed by examples from the area of expertise from the selected contributor. The second part of the book attempts to integrate previously analyzed technologies into the different aspects of molecular diagnostics, such as identification of genetically modified organisms, stem cells, pharmacogenomics, modern forensic science, molecular microbiology, and genetic diagnosis. Part three focuses on various everyday issues in a diagnostic laboratory, from genetic counseling and related ethical and psychological issues, to safety and quality management. Presents a comprehensive account of all new technologies and applications used in clinical diagnostic laboratories Explores a wide range of molecular-based tests that are available to assess DNA variation and changes in gene expression Offers clear translational presentations by the top molecular pathologists, clinical chemists, and molecular geneticists in the field

Plant Pathology Concepts and Laboratory Exercises, Second Edition

Plant Pathology Concepts and Laboratory Exercises, Second Edition
A Book

by Robert N. Trigiano

  • Publisher : CRC Press
  • Release : 2007-11-30
  • Pages : 576
  • ISBN : 1482226936
  • Language : En, Es, Fr & De
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Revised and updated with new concepts, case studies, and laboratory exercises, Plant Pathology Concepts and Laboratory Exercises, Second Edition supplies highly detailed and accurate information in a well-organized and accessible format. New additions to the second edition include five new topic and exercise chapters on soilborne pathogens, molecular tools, biocontrol, and plant-fungal interactions, information on in vitro pathology, an appendix on plant pathology careers, and how to use and care for the microscope. An accompanying cd-rom contains figures from the text as well as supplemental full-color photos and PowerPoint slides. Unique Learning Tools Retaining the informal style of the previous edition, this volume begins each topic with a concept box to highlight important ideas. Several laboratory exercises support each topic and cater to a wide range of skill sets from basic to complex. Procedure boxes for the experimental exercises give detailed outlines and comments on the experiments, step by step instruction, anticipated results, and thought provoking questions. Case studies of specific diseases and processes are presented as a bulleted list supplying essential information at a glance. Comprehensive Coverage Divided into six primary parts, this valuable reference introduces basic concepts of plant pathology with historical perspectives, fundamental ideas of disease, and disease relationships with the environment. It details various disease-causing organisms including viruses, prokaryotic organisms, plant parasitic nematodes, fungi, plant parasitic seed plants, and other biotic and abiotic diseases. Exploring various plant-pathogen interactions including treatments of molecular attack strategies, extracellular enzymes, host defenses, and disruption of plant function, the book presents the basic ideas of epidemiology, control strategies, and disease diagnosis.

Plant Pathology Concepts and Laboratory Exercises, Third Edition

Plant Pathology Concepts and Laboratory Exercises, Third Edition
A Book

by Bonnie H. Ownley,Robert N. Trigiano

  • Publisher : CRC Press
  • Release : 2016-03-26
  • Pages : 450
  • ISBN : 9781466500815
  • Language : En, Es, Fr & De
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Continuing in the tradition of its predecessors, this new edition combines an informal, easy to read style with a thorough introduction to concepts and terminology of plant pathology. After reviewing fundamental concepts, the book discusses groups of plant pathogens and molecular tools for studying them, pathogen interactions, epidemiology and disease control, and special topics in plant pathology. The book details various disease-causing organisms, including viruses, fungi, prokaryotics, nematodes, and various biotic agents. It also examines various plant-pathogen interactions, molecular attack strategies, extracellular enzymes, host defenses, and disruption of plant function.

Practical Oncologic Molecular Pathology

Practical Oncologic Molecular Pathology
Frequently Asked Questions

by Yi Ding,Linsheng Zhang

  • Publisher : Springer Nature
  • Release : 2021-07-10
  • Pages : 449
  • ISBN : 3030732274
  • Language : En, Es, Fr & De
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This book is a review and high-yield reference on the clinical molecular diagnostics of malignant neoplasms. It aims to address the practical questions frequently encountered in the molecular oncology practice, as well as key points and pitfalls in the clinical interpretation of molecular tests in guiding precision cancer management. The text uses a Q&A format and case presentations, with emphasis on understanding the molecular test methods, diagnosis, classification, risk assessment and clinical correlation. Starting with an update on the molecular biology of cancer, the book focuses on the topics related to molecular diagnostics and genetics-based precision oncology. Separate chapters are dedicated to discussion of the bioinformatics for the analysis of genetic/genomic data generated from molecular assays, and quality control (QC)/quality assurance (QA) programs in the clinical laboratories; both are critical in producing high quality results for clinical care of cancer patients. These are followed by organ system-based reviews and discussions on the molecular genetic abnormalities and related tests covering diverse types of common to rare malignant neoplasms. This book also provides up-to-date knowledge related to malignant neoplasms, discusses the established as well as evolving requirements for pathologic diagnosis of these malignancies. It also discusses the cost effective utilization of molecular tests in clinical oncology. Written by experts in the field, Practical Oncologic Molecular Pathology serves as a valuable reference for practicing pathologists, fellows, residents and other health care professionals.

Molecular Pathology: An Update, An Issue of the Clinics in Laboratory Medicine, Ebook

Molecular Pathology: An Update, An Issue of the Clinics in Laboratory Medicine, Ebook
A Book

by Martin H. Bluth

  • Publisher : Elsevier Health Sciences
  • Release : 2018-05-23
  • Pages : 249
  • ISBN : 0323610730
  • Language : En, Es, Fr & De
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This updated issue of Clinics in Laboratory Medicine, edited by Martin H. Bluth, will focus on Molecular Pathology. Topics include, but are not limited to, The Impact of Molecular Pathology on the Practice of Pathology; Molecular pathology techniques; Clinical Implication of MicroRNAs in Molecular Pathology; Diagnostic Molecular Microbiology; Molecular Pathology in Transfusion Medicine; Molecular Diagnosis of Hematopoietic Neoplasms; Molecular Diagnostics in Colorectal Carcinoma; Molecular Diagnostics in the Neoplasms of Small Intestine and Appendix; Molecular Diagnostics in Esophageal and Gastric Neoplasms; Molecular Diagnostics in the Neoplasms of the Pancreas, Liver, Gall Bladder, and Extrahepatic Biliary Tract; Current Applications of Molecular Genetic Technologies to the Diagnosis and Treatment of Cutaneous Melanocytic Neoplasms; Breast Carcinoma; and Gynecologic Cancers.

Laboratory Exercises in Plant Pathology: An Instructional Kit (Students Manual)

Laboratory Exercises in Plant Pathology: An Instructional Kit (Students Manual)
A Book

by A.B.A.M. Baudoin

  • Publisher : Scientific Publishers
  • Release : 2011-06-14
  • Pages : 215
  • ISBN : 9387869199
  • Language : En, Es, Fr & De
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The exercises in this collection are designed for introductory laboratory courses in general plant pathology at the college level. They are aimed at under-graduate students in Plant Science, Biology, Agronomy, Horticulture, Forestry, as well as Plant Pathology and pest Management and many exercises are suitable for graduate courses as well. However, the focus is on developing an experimental as well as observational approach to principles of plant disease development, diagnosis and control - principles that extend beyond the particular organisms used.

Molecular Pathology

Molecular Pathology
A Book

by John M. S. Bartlett,Abeer Shaaban,Fernando Schmitt

  • Publisher : Cambridge University Press
  • Release : 2016-03-01
  • Pages : 400
  • ISBN : 1107443466
  • Language : En, Es, Fr & De
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Practical overview of current molecular techniques and their applications in each organ system, for practising and trainee pathologists.

40 Inquiry Exercises for the College Biology Lab

40 Inquiry Exercises for the College Biology Lab
A Book

by A. Daniel Johnson

  • Publisher : NSTA Press
  • Release : 2009
  • Pages : 514
  • ISBN : 1933531398
  • Language : En, Es, Fr & De
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Drawing from the author's own work as a lab dveloper, coordinator, and instructor, this one-of-a-kind text for college biology teachers uses the inquiry method in presenting 40 different lab exercises that make complicated biology subjects accessible to major and nonmajors alike. The volume offers a review of various aspects of inquiry, including teaching techniques, and covers 16 biology topics, including DNA isolation and analysis, properties of enzymes, and metabolism and oxygen consumption. Student and teacher pages are provided for each of the 16 topics.

Molecular Pathology in Clinical Practice

Molecular Pathology in Clinical Practice
A Book

by Debra G.B. Leonard

  • Publisher : Springer
  • Release : 2016-02-02
  • Pages : 1001
  • ISBN : 331919674X
  • Language : En, Es, Fr & De
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This authoritative textbook offers in-depth coverage of all aspects of molecular pathology practice and embodies the current standard in molecular testing. Since the successful first edition, new sections have been added on pharmacogenetics and genomics, while other sections have been revised and updated to reflect the rapid advances in the field. The result is a superb reference that encompasses molecular biology basics, genetics, inherited cancers, solid tumors, neoplastic hematopathology, infectious diseases, identity testing, HLA typing, laboratory management, genomics and proteomics. Throughout the text, emphasis is placed on the molecular variations being detected, the clinical usefulness of the tests and important clinical and laboratory issues. The second edition of Molecular Pathology in Clinical Practice will be an invaluable source of information for all practicing molecular pathologists and will also be of utility for other pathologists, clinical colleagues and trainees.

Announcement

Announcement
A Book

by University of California, Los Angeles. School of Medicine

  • Publisher : Unknown Publisher
  • Release : 1992
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Essential Forensic Pathology

Essential Forensic Pathology
Core Studies and Exercises

by Gilbert Corrigan

  • Publisher : CRC Press
  • Release : 2012-02-14
  • Pages : 248
  • ISBN : 1439876673
  • Language : En, Es, Fr & De
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A myriad of different scenarios await those entering the field of forensic pathology, ranging from gunshot wounds to asphyxiation to explosives to death from addiction. Essential Forensic Pathology: Core Studies and Exercises helps prepare pathologists in training by establishing what they must know about the most common death scenes they will enco

Federal Register

Federal Register
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2012-11
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Cancer Research

Cancer Research
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1997
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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AFIP Letter

AFIP Letter
A Book

by Armed Forces Institute of Pathology (U.S.)

  • Publisher : Unknown Publisher
  • Release : 1995
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Plant Propagation Concepts and Laboratory Exercises

Plant Propagation Concepts and Laboratory Exercises
A Book

by Caula A. Beyl,Robert N. Trigiano

  • Publisher : CRC Press
  • Release : 2016-01-06
  • Pages : 520
  • ISBN : 1466503882
  • Language : En, Es, Fr & De
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Includes a DVD Containing All Figures and Supplemental Images in PowerPoint This new edition of Plant Propagation Concepts and Laboratory Exercises presents a robust view of modern plant propagation practices such as vegetable grafting and micropropagation. Along with foundation knowledge in anatomy and plant physiology, the book takes a look into the future and how cutting edge research may impact plant propagation practices. The book emphasizes the principles of plant propagation applied in both temperate and tropical environments. In addition to presenting the fundamentals, the book features protocols and practices that students can apply in both laboratory and field experiences. The book shows readers how to choose the best methods for plant propagation including proper media and containers as well as performing techniques such as budding, cutting, layering, grafting, and cloning. It also discusses how to recognize and cope with various propagation challenges. Also included are concept chapters highlighting key information, laboratory exercises, anticipated laboratory results, stimulating questions, and a DVD containing all the figures in the book as well as some supplemental images.

Molecular Applications in Cytology

Molecular Applications in Cytology
A Book

by Fernando C. Schmitt

  • Publisher : Springer
  • Release : 2018-07-24
  • Pages : 268
  • ISBN : 3319749420
  • Language : En, Es, Fr & De
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This book is intended for practicing pathologists and cytopathologists, as well as for pathology trainees and cytotechnicians. It starts with a detailed description of the extremely important pre-analytical phase for molecular testing followed by a presentation of the key tests and their application in different organs, e.g. the lung or thyroid. Step-by-step instructions for the different assays, reporting and clinical integration of the test results are discussed. The authors help the reader to benefit from their experiences by providing a valuable tool for the implementation of these techniques in daily practice. Though the use of molecular techniques is well established in surgical biopsies, to date they are not widely used in connection with cytological material. However, in some fields like lung cancer or aspirates from the pancreas and biliary tract the only available material for diagnosis is the cytological preparation a fact that has created a need for the standardization of molecular techniques on cytology.

Review Manual to Henry's Clinical Diagnosis and Management by Laboratory Methods

Review Manual to Henry's Clinical Diagnosis and Management by Laboratory Methods
A Book

by Katherine I. Schexneider

  • Publisher : W B Saunders Company
  • Release : 2005
  • Pages : 467
  • ISBN : 9781416000532
  • Language : En, Es, Fr & De
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This comprehensive workbook companion to Henry's Clinical Diagnosis and Management by Laboratory Methods is designed to help pathology residents prepare for their board certification exams. It covers information that is likely to appear on the boards and that will also prove useful for day-to-day reference in the post-qualification years. Using a parallel organization to Dr. Henry's classic textbook, the workbook presents concise, bullet-point summaries of every important concept, as well as more than 1,320 review questions and answers, word association drills, image interpretation exercises, and a mathematical formula exam to challenge users' mastery of the material. Accompanies the most authoritative reference book in clinical and laboratory pathology, Henry's Clinical Diagnosis and Management by Laboratory Methods. Presents concise, bullet-point summaries of all essential information in 7 key areas: The Clinical Laboratory · Clinical Chemistry · Urine and Other Body Fluids · Hematology, Coagulation and Transfusion Medicine · Immunology and Immunopathology · Medical Microbiology · and Molecular Pathology. Offers more than 1,320 multiple-choice test questions and answers to evaluate readers' knowledge. Provides extensive practice in using the mathematical formulas needed in hematology, blood banking, and chemistry. Includes a comprehensive picture identification segment to mimic the Kodachrome Simulation Examination part of the board exam, with 40 multiple-choice questions and answers based on color images.