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Lipid-Based Nanocarriers for Drug Delivery and Diagnosis

Lipid-Based Nanocarriers for Drug Delivery and Diagnosis
A Book

by Muhammad Raza Shah,Muhammad Imran,Shafi Ullah

  • Publisher : William Andrew
  • Release : 2017-06-07
  • Pages : 372
  • ISBN : 0323527302
  • Language : En, Es, Fr & De
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Lipid-Based Nanocarriers for Drug Delivery and Diagnosis explores the present state of widely used lipid-based nanoparticulate delivery systems, such as solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC), nanoliposomes, micelles, nanoemulsions, nanosuspensions and lipid nanotubes. The various types of lipids that can be exploited for drug delivery and their chemical composition and physicochemical characteristics are reviewed in detail, along with their characterization aspects and effects of their dimensions on drug delivery systems behavior in-vitro and in-vivo. The book covers the effective utilization of these lipids based systems for controlled and targeted delivery of potential drugs/genes for enhanced clinical efficacy. Provides the present state of widely used lipid-based nanoparticulate delivery systems Explores how lipid-based nanocarriers improve drug delivery safety Describes the nanoformulation design and the preparation methods of lipid-based nanocarriers

Lipid-Based Nanocarriers for Drug Delivery and Diagnosis

Lipid-Based Nanocarriers for Drug Delivery and Diagnosis
A Book

by Muhammad Raza Shah,Muhammad Imran,Shafi Ullah

  • Publisher : William Andrew
  • Release : 2017-06-15
  • Pages : 316
  • ISBN : 9780323527293
  • Language : En, Es, Fr & De
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In the drug discovery process, it is estimated that approximately 10,000 chemical entities need to be tested before one would eventually reach the consumer market. Major reasons for this high failure rate are drug toxicity, low bioavailability, biological degradation and inadvertent intrinsic side effects. Nanotechnology is exponentially expanding in the area of medicines, therapeutics, diagnostics and drug delivery. A delivery system is a formulation or a device that introduces bioactive compounds into the body and improves their efficacy and safety by controlling the rate and targeted release of the bioactive compound. Among the colloidal vectors proposed for the controlled delivery and targeting of drugs and other biologically active compounds, lipid-based nanocarriers has acquired an increasing role due to a number of peculiar technological and physical features. These carriers are generally composed of physiological lipids well tolerated by human body. The potential advantages of lipid-based nanocarriers application over other carriers are of their high biocompatibility, higher drug loading capacity and scalability. This book explores the present state of widely used lipid-based nanoparticulate delivery systems such as solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC), nanoliposomes, micelles, nanoemulsions, nanosuspensions and lipid nanotubes. The various types of lipids that can be exploited for drug delivery and their chemical composition and physicochemical characteristics are reviewed in detail. The characterization aspects and effects of their dimensions on drug delivery systems behaviour in in-vitro and in-vivo are also described. The book covers the effective utilization of these lipids based systems for controlled and targeted delivery of potential drugs/ genes for enhanced clinical efficacy. The role of lipid nanocarriers in Nanomedicine, diagnostic and therapy is also covered. Explores the present state of widely used lipid-based nanoparticulate delivery systems Explores how lipid-based nanocarriers improves drug delivery safety Describes the nanoformulation design, the preparation methods of lipid-based nanocarriers

Lipid Nanocarriers for Drug Targeting

Lipid Nanocarriers for Drug Targeting
A Book

by Alexandru Mihai Grumezescu

  • Publisher : William Andrew
  • Release : 2018-04-16
  • Pages : 674
  • ISBN : 012813688X
  • Language : En, Es, Fr & De
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Lipid Nanocarriers for Drug Targeting presents recent advances in the area of lipid nanocarriers. The book focuses on cationic lipid nanocarriers, solid lipid nanocarriers, liposomes, thermosensitive vesicles, and cubosomes, with applications in phototherapy, cosmetic and others. As the first book related to lipid nanocarriers and their direct implication in pharmaceutical nanotechnology, this important reference resource is ideal for biomaterials scientists and those working in the medical and pharmaceutical industries that want to learn more on how lipids can be used to create more effective drug delivery systems. Highlights the most commonly used types of lipid nanocarriers and explains how they are applied in pharmacy Shows how lipid nanocarriers are used in different types of treatment, including oral medicine, skin repair and cancer treatment Assesses the pros and cons of using different lipid nanocarriers for different therapies

Nanocarriers for Drug Delivery

Nanocarriers for Drug Delivery
Nanoscience and Nanotechnology in Drug Delivery

by Shyam Mohapatra,Shivendu Ranjan,Nandita Dasgupta,Raghvendra Kumar Mishra,Sabu Thomas

  • Publisher : Elsevier
  • Release : 2018-10-05
  • Pages : 694
  • ISBN : 0128140348
  • Language : En, Es, Fr & De
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Nano-carriers for Drug Delivery: Nanoscience and Nanotechnology in Drug Delivery presents recent discoveries in research on the pharmaceutical applications of the various types of nanosystem-based drug delivery systems. As many nanosystems have reached the market over the past decade, this book proves their benefits to patients. It explores these new carriers and the advances in drug delivery they have facilitated. Reflecting the interdisciplinary nature of the subject matter, the book includes experts from different fields, and with various backgrounds and expertise. It will appeal to researchers and students from different disciplines, such as materials science, technology and various biomedical fields. Coverage includes industrial applications that bridge the gap between lab-based research and practical industrial use. The resulting work is a reference and practical source of guidance for researchers, students and scientists working in the fields of nanotechnology, materials science and technology and biomedical science. Enables readers from different fields to access recent research and protocols across traditional boundaries Focuses on protocols and techniques, as well as the knowledge base of the field, thus enabling those in R&D to learn about, and successfully deploy, cutting-edge techniques Includes sections on nanocarrier systems

Organic Materials as Smart Nanocarriers for Drug Delivery

Organic Materials as Smart Nanocarriers for Drug Delivery
A Book

by Alexandru Mihai Grumezescu

  • Publisher : William Andrew
  • Release : 2018-03-26
  • Pages : 768
  • ISBN : 0128136642
  • Language : En, Es, Fr & De
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Organic Materials as Smart Nanocarriers for Drug Delivery presents the latest developments in the area of organic frameworks used in pharmaceutical nanotechnology. An up-to-date overview of organic smart nanocarriers is explored, along with the different types of nanocarriers, including polymeric micelles, cyclodextrins, hydrogels, lipid nanoparticles and nanoemlusions. Written by a diverse range of international academics, this book is a valuable reference for researchers in biomaterials, the pharmaceutical industry, and those who want to learn more about the current applications of organic smart nanocarriers. Explores the most recent molecular- and structure-based applications of organic smart nanocarriers in drug delivery Highlights different smart nanocarriers and assesses their intricate organic structural properties for improving drug delivery Assesses how molecular organic frameworks lead to more effective drug delivery systems

Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes

Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes
A Book

by Vijay Mishra,Prashant Kesharwani,Mohd Cairul Iqbal Mohd Amin,Arun Iyer

  • Publisher : Academic Press
  • Release : 2017-05-23
  • Pages : 552
  • ISBN : 0128097183
  • Language : En, Es, Fr & De
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Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes provides an overview of the important aspects of nanomedicine in order to illustrate how to design and develop novel and effective drug delivery systems using nanotechnology. The book is organized into three sections, beginning with an introduction to nanomedicine and its associated issues. Section two discusses the latest technologies in nanomedicine, while the third section covers future developments and challenges in the field. By focusing on the design, synthesis, and application of a variety of nanocarriers in drug and gene delivery, this book provides pharmaceutical and materials science students, professors, clinical researchers, and industry scientists with a valuable resource aimed at tackling the challenges of delivering drugs and genes in a more targeted manner. Explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advances in cutting-edge nanomedical technologies Contains contributions from world-renowned experts and researchers working in the area of nanomedicine and drug delivery Covers the associated challenges and potential solutions to working with nanotechnology in drug delivery Highlights crucial topics, such as biopharmaceutical and toxicity issues, quality by design, drug targeting, and more

Multifunctional Systems for Combined Delivery, Biosensing and Diagnostics

Multifunctional Systems for Combined Delivery, Biosensing and Diagnostics
A Book

by Alexandru Mihai Grumezescu

  • Publisher : William Andrew
  • Release : 2017-05-03
  • Pages : 372
  • ISBN : 0323527264
  • Language : En, Es, Fr & De
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Multifunctional Systems for Combined Delivery, Biosensing, and Diagnostics explores how multifunctional nanocarriers are being used in combined delivery and diagnostics in contemporary medicine. Particular attention is given to efforts to i) reduce the side effects of therapeutic agents, ii) increase the pharmacological effect, and iii) improve aqueous solubility and chemical stability of different therapeutic agents. The chapters focus on applications of nanostructured materials and nanocarriers, highlighting how these can be used effectively in both diagnosis and delivery. This applied focus makes the book an important reference source for those wanting to learn more about how specific nanomaterials and nanotechnology systems can help to solve drug delivery and diagnostics problems. This book is a valuable resource for materials scientists, bioengineers, and medical researchers who are looking for an applications-oriented guide on how nanotechnology and nanomaterials can be used effectively throughout the medical treatment process, from diagnosis to treatment. Explores the benefits of using a variety of nanomaterials as drug delivery agents Explains how nanocarriers can reduce the side effects of therapeutic agents Provides an analysis of the pros and cons of using specific nanocarriers to solve particular diagnosis and delivery problems

Nanomaterials for Drug Delivery and Therapy

Nanomaterials for Drug Delivery and Therapy
A Book

by Alexandru Mihai Grumezescu

  • Publisher : William Andrew
  • Release : 2019-03-14
  • Pages : 580
  • ISBN : 0128166290
  • Language : En, Es, Fr & De
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Nanomaterials for Drug Delivery and Therapy presents recent advances in the field of nanobiomaterials and their important applications in drug delivery, therapy and engineering. The book offers pharmaceutical perspectives, exploring the development of nanobiomaterials and their interaction with the human body. Chapters show how nanomaterials are used in treatments, including neurology, dentistry and cancer therapy. Authored by a range of contributors from global institutions, this book offers a broad, international perspective on how nanotechnology-based advances are leading to novel drug delivery and treatment solutions. It is a valuable research resource that will help both practicing medics and researchers in pharmaceutical science and nanomedicine learn more on how nanotechnology is improving treatments. Assesses the opportunities and challenges of nanotechnology-based drug delivery systems Explores how nanotechnology is being used to create more efficient drug delivery systems Discusses which nanomaterials make the best drug carriers

Application of Nanotechnology in Drug Delivery

Application of Nanotechnology in Drug Delivery
A Book

by Ali Demir Sezer

  • Publisher : BoD – Books on Demand
  • Release : 2014-07-25
  • Pages : 554
  • ISBN : 9535116282
  • Language : En, Es, Fr & De
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This book collects reviews and original articles from eminent experts working in the interdisciplinary arena of nanotechnology use in drug delivery. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of nanotechnology application of drug delivery. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

Nanoparticulate Drug Delivery Systems

Nanoparticulate Drug Delivery Systems
A Book

by Deepak Thassu,Michel Deleers,Yashwant Vishnupant Pathak

  • Publisher : CRC Press
  • Release : 2007-03-30
  • Pages : 376
  • ISBN : 9781420008449
  • Language : En, Es, Fr & De
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With the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. Nanoparticulate Drug Delivery Systems addresses the scientific methodologies, formulation, processing, applications, recent trends, and e

Handbook of Materials for Nanomedicine

Handbook of Materials for Nanomedicine
Lipid-Based and Inorganic Nanomaterials

by Vladimir Torchilin

  • Publisher : CRC Press
  • Release : 2020-05-08
  • Pages : 504
  • ISBN : 1000067041
  • Language : En, Es, Fr & De
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In the fast-developing field of nanomedicine, a broad variety of materials have been used for the development of advanced delivery systems for drugs, genes, and diagnostic agents. With the recent breakthroughs in the field, we are witnessing a new age of disease management, which is governed by precise regulation of dosage and delivery. This book presents the advances in the use of lipid-based and inorganic nanomaterials for medical imaging, diagnosis, theranostics, and drug delivery. The materials discussed include liposome-scaffold systems, elastic liposomes, targeted liposomes, solid lipid nanoparticles, lipoproteins, exosomes, porous inorganic nanomaterials, silica nanoparticles, and inorganic nanohybrids. The book provides all available information about them and describes in detail their advantages and disadvantages and the areas where they could be utilized successfully.

Nanoparticulate Drug Delivery Systems

Nanoparticulate Drug Delivery Systems
A Book

by Raj K. Keservani,Anil K. Sharma

  • Publisher : CRC Press
  • Release : 2019-01-23
  • Pages : 422
  • ISBN : 1351137247
  • Language : En, Es, Fr & De
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Focusing on nanoparticulate nanocarriers and recent advances in the field of drug delivery, the volume begins with chapters that provide an informative introduction to polymeric nanoparticles—their general physicochemical features and characteristics, their applications in drug delivery systems, and the challenges involved. Specific applications are discussed, with attention paid to treatment of particular diseases and disorders and the targeting of specific organs. Part 2 looks at more specific applications and techniques of nanoparticulate nanocarriers for drug delivery, such as the use of magnetic nanoparticles, gold nanoparticles in therapeutics, and superparamagnetic iron oxide nanoparticles (SPIONs) for the treatment of cancer. Part 3 discusses lipid-based nanoparticulates for various applications, including skin care. The last section of the book explores some of the newer nanoarchitectures, including dendrimers in gene delivery and carbon nanotubes for drug delivery. Together, the insightful research presented here provides valuable information for those involved in this area, including scientists and researchers and faculty and upper-level students, as well as for industry professionals.

Nanocarriers for the Delivery of Combination Drugs

Nanocarriers for the Delivery of Combination Drugs
A Book

by Sanjula Baboota,Javed Ali

  • Publisher : Elsevier
  • Release : 2021-06-01
  • Pages : 400
  • ISBN : 0128209402
  • Language : En, Es, Fr & De
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Nanocarriers for the Delivery of Combination Drugs focuses on the role of nanocarriers in the delivery of combination drugs for the management and treatment of various diseases. Combination drug therapy success has been limited due to the inability of the individual drugs to achieve the desired therapeutic outcome when they are delivered in the individual form and reasons for this can be the difference in physiochemical and biopharmaceutical characteristics of drugs leading to variable results. Nanocarriers have been used for the co-delivery of drug combinations for delivering drugs at the right place and right time in combinations. Nanocarriers belonging to the category of polymeric nanoparticles, dendrimers, lipidic nanocarriers like nanoemulsions, liposomes, solid lipid nanoparticles, nanostructured lipid carriers, are now being used for drug delivery of combination drugs. The primary focus of Nanocarriers for the Delivery of Combination Drugs is to assimilate all the information available pertaining to the application of various nanocarrier technology for the delivery of combination drugs of synthetic and natural origin and encompassing small and large molecules. It is an important reference source for pharmaceutical scientists and biomaterials scientists, who are looking to gain an increased understanding of how nanotechnology is improving the efficiency of combination drug delivery. Outlines how nanocarriers are used to enhance combination drug delivery systems Assesses the major challenges of delivering combination drugs successfully, and explains how nanocarriers can help meet these challenges Explores the characteristics of a variety of nanocarrier material types

Drug Carrier Systems

Drug Carrier Systems
A Book

by Frits H. Roerdink,Frederik Herman D. Roerdink,A. M. Kroon

  • Publisher : John Wiley & Sons
  • Release : 1989
  • Pages : 330
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Presents the main developments of the past 20 years, relating advances in systems that release the active drug in a sustained and controlled way, and new drugs that address more specifically the tissues and cells with which they are designed to interact. Considers the problems of biodistribution and biodegradation, with in-depth discussion of the selectivity and toxicity of the drugs administered by the various carrier systems. Topics covered range from antibodies, polymers, liposomes, erythrocytes and erythrocyte ghosts, to implantable infusion pumps. Acidic paper. Annotation copyrighted by Book News, Inc., Portland, OR

Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer

Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer
A Book

by Prashant Kesharwani

  • Publisher : Academic Press
  • Release : 2019-01-26
  • Pages : 340
  • ISBN : 0128163674
  • Language : En, Es, Fr & De
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Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer using cutting-edge nanomedical technologies. Topics discussed include polymeric nanoparticles, solid lipid nanoparticles, liposomes, dendrimers, micelles and nanoemulsions. Provides an overview of an array of nanotechnology-based drug delivery systems Examines the design, synthesis and application of different nanocarriers in drug and gene delivery Provides an in-depth understanding of the design of targeted nanotherapeutics and technologies and its implication in various site-specific cancers

PAIN – Novel targets and new technologies

PAIN – Novel targets and new technologies
A Book

by Susan Hua,Peter John Cabot

  • Publisher : Frontiers Media SA
  • Release : 2015-01-22
  • Pages : 95
  • ISBN : 2889193942
  • Language : En, Es, Fr & De
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The problem of clinical pain management is complex and far-reaching, as it encompasses many different types of pain, such as arthritis, musculoskeletal conditions, neuropathic pain, and visceral pain. It is widely known that many of the well-established analgesic pathways are centrally based, involving spinal and supraspinal sites. However, pain can also be effectively controlled by peripheral pathways. The analgesics market is growing and the driving forces are the aging population and need for better therapeutic benefits. There are various analgesic products that are available that can be administered by various routes, yet research is active in identifying new technologies for better drug targeting and novel targets to gain improved therapeutic efficiency. This e-Book “PAIN – novel targets and new technologies” has brought together experts in the field of pain at the physiological, pharmacological and pharmaceutical levels to discuss novel pain targets and new pain technologies across the various types of pain. This information is presented as novel research findings, short communications and review articles. The goal of this e-Book is to generate further collaborative discussion on the future and direction of pain therapies.

Advanced Technology for Delivering Therapeutics

Advanced Technology for Delivering Therapeutics
A Book

by Sabyasachi Maiti,Kalyan Kumar Sen

  • Publisher : BoD – Books on Demand
  • Release : 2017-05-11
  • Pages : 184
  • ISBN : 9535131214
  • Language : En, Es, Fr & De
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The goal of any novel drug delivery system is to provide therapeutic benefits to the patients by increasing duration of drug action, reducing dosing frequency, and controlling drug release rate at the target site, thereby reducing unwanted side effects. Advanced Technology for Delivering Therapeutics is a reference book that covers recent developments in the field of drug delivery science and technology. The purpose of this book is to bring together descriptions of some selective technologies including new and promising nanotechnology currently being investigated for drug delivery applications. This book is a useful source of information for graduate and post-graduate students of pharmacy and biomedical science; pharmaceutical

Drug Delivery Nanoparticles Formulation and Characterization

Drug Delivery Nanoparticles Formulation and Characterization
A Book

by Yashwant Pathak,Deepak Thassu

  • Publisher : CRC Press
  • Release : 2016-04-19
  • Pages : 416
  • ISBN : 1420078054
  • Language : En, Es, Fr & De
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Exploring fundamental concepts, Drug Delivery Nanoparticles Formulation and Characterization presents key aspects of nanoparticulate system development for various therapeutic applications and provides advanced methods used to file for regulatory approval.This comprehensive guide features:Process Analytical Techniques (PAT) used in manufacturing Na

Smart Pharmaceutical Nanocarriers

Smart Pharmaceutical Nanocarriers
A Book

by Torchilin Vladimir P

  • Publisher : World Scientific
  • Release : 2015-12-31
  • Pages : 564
  • ISBN : 1783267240
  • Language : En, Es, Fr & De
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Drug delivery systems and pharmaceutical nanocarriers that respond to different types of stimuli, such as internal ones, intrinsic for the pathological area (changes in pH, temperature, redox condition, activity of certain enzymes), or external, artificially applied (magnetic field, ultrasound, various irradiations), represent an important and continuously growing area of research. Smart Phramaceutical Nanocarriers overviews the various stimuli used for drug release and delivery by smart pharmaceutical carriers and presents cutting-edge research and the newest data from the leading laboratories in each area.

Nanostructures for Drug Delivery

Nanostructures for Drug Delivery
A Book

by Ecaterina Andronescu,Alexandru Mihai Grumezescu

  • Publisher : Elsevier
  • Release : 2017-03-24
  • Pages : 1024
  • ISBN : 0323461492
  • Language : En, Es, Fr & De
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Nanostructures for Drug Delivery extensively covers the various nanostructured products that have been tested as carriers in target drug delivery systems. In addition, the book analyses the advantages of, and issues related to, using nanostructured materials in drug delivery systems, also detailing various nanocarrier preparation techniques. As delivering the drug to the target site is a major problem in providing effective treatment for many diseases, this book covers the latest advancements in numerous nanotechnological products that are being used in disease detection, controlled drug delivery, as biosensors, and in tissue engineering that have been developed for more efficient patient healthcare. Due to the versatility of nanostructured materials, it is now possible to deliver a drug at its target site in a more accurate and efficient way. This volume is an up-to-date, state-of-the-art work that highlights the principal mechanistic aspects related to the delivery of active nanoscale therapeutic agents (natural or synthetic) and their release profile in different environmental media. It highlights nanoscale encapsulation strategies and discusses both organic and inorganic nanomaterials as carriers and delivery platforms. Demonstrates how nanostructures are successfully employed in drug delivery stems and as drug delivery agents, allowing biomaterials scientists and biochemists to create more effective drug delivery systems Offers an overview of recent research into the use of nanostructures in drug delivery techniques in a cogent, synthesized way, allowing readers to quickly familiarize themselves with this area Includes examples of how the application of nanostructures have improved the efficiency of drug delivery systems, showing medical scientists how they are beneficial