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Genomics and Biotechnological Advances in Veterinary, Poultry, and Fisheries

Genomics and Biotechnological Advances in Veterinary, Poultry, and Fisheries
A Book

by Yashpal Singh Malik,Debmalya Barh,Vasco Azevedo,S.M. Paul Khurana

  • Publisher : Academic Press
  • Release : 2019-09-14
  • Pages : 564
  • ISBN : 0128163534
  • Language : En, Es, Fr & De
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Genomics and Biotechnological Advances in Veterinary, Poultry, and Fisheries is a comprehensive reference for animal biotechnologists, veterinary clinicians, fishery scientists, and anyone who needs to understand the latest advances in the field of next generation sequencing and genomic editing in animals and fish. This essential reference provides information on genomics and the advanced technologies used to enhance the production and management of farm and pet animals, commercial and non-commercial birds, and aquatic animals used for food and research purposes. This resource will help the animal biotechnology research community understand the latest knowledge and trends in this field. Presents biological applications of cattle, poultry, marine and animal pathogen genomics Discusses the relevance of biomarkers to improve farm animals and fishery Includes recent approaches in cloning and transgenic cattle, poultry and fish production

Gene Editing

Gene Editing
Technologies and Applications

by Yuan-Chuan Chen,Shiu-Jau Chen

  • Publisher : BoD – Books on Demand
  • Release : 2019-05-29
  • Pages : 108
  • ISBN : 1789845084
  • Language : En, Es, Fr & De
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Gene-editing technologies (e.g., ZFNs, TALENs, and CRISPRs/Cas9) have been extensively used as tools in basic research. They are further applied in manufacturing agricultural products, food, industrial products, medicinal products, etc. Particularly, the discovery of medicinal products using gene-editing technologies will open a new era for human therapeutics. Though there are still many technical and ethical challenges ahead of us, more and more products based on gene-editing technologies have been approved for marketing. These technologies are promising for multiple applications. Their development and implications should be explored in the broadest context possible. Future research directions should also be highlighted. In this book, the applications, perspectives, and challenges of gene-editing technologies are significantly demonstrated and discussed.

Genome Editing in Animals

Genome Editing in Animals
Methods and Protocols

by Izuho Hatada

  • Publisher : Humana
  • Release : 2018-08-08
  • Pages : 256
  • ISBN : 9781493983933
  • Language : En, Es, Fr & De
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This volume details protocols that can be used for generation of knockout animals. Chapters guide the reader through basic protocols for three genome editing technologies, target design tools, and specific protocols for each animal. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Genome Editing in Animals: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Targeted Genome Editing Using Site-Specific Nucleases

Targeted Genome Editing Using Site-Specific Nucleases
ZFNs, TALENs, and the CRISPR/Cas9 System

by Takashi Yamamoto

  • Publisher : Springer
  • Release : 2015-01-05
  • Pages : 205
  • ISBN : 4431552278
  • Language : En, Es, Fr & De
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This book serves as an introduction to targeted genome editing, beginning with the background of this rapidly developing field and methods for generation of engineered nucleases. Applications of genome editing tools are then described in detail, in iPS cells and diverse organisms such as mice, rats, marine invertebrates, fish, frogs, and plants. Tools that are mentioned include zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and CRISPR/Cas9, all of which have received much attention in recent years as breakthrough technologies. Genome editing with engineered nucleases allows us to precisely change the target genome of living cells and is a powerful way to control functional genes. It is feasible in almost all organisms ranging from bacteria to plants and animals, as well as in cultured cells such as ES and iPS cells. Various genome modifications have proven successful, including gene knockout and knock-in experiments with targeting vectors and chromosomal editing. Genome editing technologies hold great promise for the future, for example in biomedical research, clinical medicine, and generation of crops and livestock with desirable traits. A wide range of readers will find this book interesting, and with its focus on applications in a variety of organisms and cells, the book will be valuable for life scientists in all fields.

Human Genome Editing

Human Genome Editing
Science, Ethics, and Governance

by National Academies of Sciences, Engineering, and Medicine,National Academy of Medicine,National Academy of Sciences,Committee on Human Gene Editing: Scientific, Medical, and Ethical Considerations

  • Publisher : National Academies Press
  • Release : 2017-08-13
  • Pages : 328
  • ISBN : 0309452880
  • Language : En, Es, Fr & De
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Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.

Animal Biotechnology 2

Animal Biotechnology 2
Emerging Breeding Technologies

by Heiner Niemann,Christine Wrenzycki

  • Publisher : Springer
  • Release : 2018-08-01
  • Pages : 303
  • ISBN : 331992348X
  • Language : En, Es, Fr & De
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This two-volume textbook provides a comprehensive overview on the broad field of Animal Biotechnology with a special focus on livestock reproduction and breeding. The reader will be introduced to a variety of state-of-the-art technologies and emerging genetic tools and their applications in animal production. Also, ethics and legal aspects of animal biotechnology will be discussed and new trends and developments in the field will be critically assessed. The two-volume work is a must-have for graduate students, advanced undergraduates and researchers in the field of veterinary medicine, genetics and animal biotechnology. This second volume is dedicated to genetic tools in animal biotechnology such as somatic cloning, transgenic technologies and the application of stem cells in livestock breeding. Also, ethics and legal aspects are discussed.

Advances in Animal Genomics

Advances in Animal Genomics
A Book

by Sukanta Mondal,Ram Lakhan Singh

  • Publisher : Academic Press
  • Release : 2020-11-25
  • Pages : 328
  • ISBN : 0128206128
  • Language : En, Es, Fr & De
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Advances in Animal Genomics provides an outstanding collection of integrated strategies involving traditional and modern - omics (structural, functional, comparative and epigenomics) approaches and genomics-assisted breeding methods which animal biotechnologists can utilize to dissect and decode the molecular and gene regulatory networks involved in the complex quantitative yield and stress tolerance traits in livestock. Written by international experts on animal genomics, this book explores the recent advances in high-throughput, next-generation whole genome and transcriptome sequencing, array-based genotyping, and modern bioinformatics approaches which have enabled to produce huge genomic and transcriptomic resources globally on a genome-wide scale. This book is an important resource for researchers, students, educators and professionals in agriculture, veterinary and biotechnology sciences that enables them to solve problems regarding sustainable development with the help of current innovative biotechnologies. Integrates basic and advanced concepts of animal biotechnology and presents future developments Describes current high-throughput next-generation whole genome and transcriptome sequencing, array-based genotyping, and modern bioinformatics approaches for sustainable livestock production Illustrates integrated strategies to dissect and decode the molecular and gene regulatory networks involved in complex quantitative yield and stress tolerance traits in livestock Ensures readers will gain a strong grasp of biotechnology for sustainable livestock production with its well-illustrated discussion

Application of Genetics and Genomics in Poultry Science

Application of Genetics and Genomics in Poultry Science
A Book

by Xiaojun Liu

  • Publisher : BoD – Books on Demand
  • Release : 2018-09-05
  • Pages : 184
  • ISBN : 1789236304
  • Language : En, Es, Fr & De
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Genetics and genomics in poultry have been the most rapidly advancing subjects since the completion of the chicken genome sequence in 2004 and have been extensively used to understand the genetic determinants of complex traits. This book intends to provide readers with a comprehensive overview of the current progress in the application of genetic and genomic science in the poultry field. The contents cover genetic variation detection, selection methods for breeding, transgenesis and genome editing, genetic basis of disease resistance, control of gene expression and regulation, reproduction and meat quality, etc. The book should prove useful to researchers and students working in related fields.

Animal Genetics and Diseases: Advances in Farming and Livestock Systems

Animal Genetics and Diseases: Advances in Farming and Livestock Systems
A Book

by Mark S. Fife,John A. Hammond,Andrea B. Doeschl-Wilson

  • Publisher : Frontiers Media SA
  • Release : 2020-02-14
  • Pages : 329
  • ISBN : 2889635236
  • Language : En, Es, Fr & De
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The new Animal Genetics and Disease 2017 conference committee organized a Research Topic for the proceedings of this inaugural conference. The meeting brought together specialists working on the interface between genomics, genetic engineering, and infectious disease, with the aims of improving animal and human health and welfare. This conference was funded by Advanced Courses and Scientific Conference at the Wellcome Genome Campus, Hinxton, UK. The conference will highlight breakthroughs in genomic technologies that are rapidly increasing our understanding of the fundamental role that host and pathogen genetics play in infections and epidemics. This Research Topic focuses on how infections spread and how they further affect the productivity of livestock systems and food supply chains. Thanks to technological advances, we now have the tools for real-time surveillance of zoonoses affecting wildlife, farm animals and animal-to-human disease transmission.

Animal Genomics

Animal Genomics
A Book

by Bhanu P. Chowdhary

  • Publisher : S Karger Ag
  • Release : 2003
  • Pages : 366
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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This publication provides an update on the current status of gene maps in different livestock and pet/companion animal species. The findings summarized in species specific commentaries and original articles testify the rapid advances made in the field of animal genomics. Of significant interest is the fact that current investigations are providing headways for two important and exciting research fronts: targeted high-resolution mapping leading to the application of genomic information in addressing questions of economic and biological significance in animals, and the initiation of whole genome sequencing projects for some of the animal species. Like in humans and mice, this will set the stage for a new level of research and real time complex analysis of the genomes of these species. Animal Genomics signifies the beginning of a new era in this field and celebrates the achievements of the past 20 years of genomics research. It will be of special interest to researchers involved in genome analysis - both gross chromosomal as well as molecular - in various animal species, and to comparative and evolutionary geneticists.

Genome Engineering via CRISPR-Cas9 System

Genome Engineering via CRISPR-Cas9 System
A Book

by Vijai Singh,Pawan K. Dhar

  • Publisher : Academic Press
  • Release : 2020-02-18
  • Pages : 384
  • ISBN : 0128181419
  • Language : En, Es, Fr & De
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Genome Engineering via CRISPR-Cas9 Systems presents a compilation of chapters from eminent scientists from across the globe who have established expertise in working with CRISPR-Cas9 systems. Currently, targeted genome engineering is a key technology for basic science, biomedical and industrial applications due to the relative simplicity to which they can be designed, used and applied. However, it is not easy to find relevant information gathered in a single source. The book contains a wide range of applications of CRISPR in research of bacteria, virus, algae, plant and mammalian and also discusses the modeling of drosophila, zebra fish and protozoan, among others. Other topics covered include diagnosis, sensor and therapeutic applications, as well as ethical and regulatory issues. This book is a valuable source not only for beginners in genome engineering, but also researchers, clinicians, stakeholders, policy makers, and practitioners interested in the potential of CRISPR-Cas9 in several fields. Provides basic understanding and a clear picture on how to design, use and implement the CRISPR-Cas9 system in different organisms Explains how to create an animal model for disease research and screening purposes using CRISPR Discusses the application of CRISPR-Cas9 systems in basic sciences, biomedicine, virology, bacteriology, molecular biology, neurology, cancer, industry, and many more

Modern Tools for Genetic Engineering

Modern Tools for Genetic Engineering
A Book

by Michael Kormann

  • Publisher : BoD – Books on Demand
  • Release : 2016-05-18
  • Pages : 226
  • ISBN : 9535123920
  • Language : En, Es, Fr & De
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Site-specific endonucleases create double-strand breaks within the genome and can be targeted to literally any genetic mutation. Together with a repair template, a correction of the defective locus becomes possible. This book offers insight into the modern tools of genome editing, their hurdles and their huge potential. A new era of in vivo genetic engineering has begun.

Editing Humanity

Editing Humanity
The CRISPR Revolution and the New Era of Genome Editing

by Kevin Davies

  • Publisher : Simon and Schuster
  • Release : 2020-10-06
  • Pages : 336
  • ISBN : 1643133942
  • Language : En, Es, Fr & De
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One of the world's leading experts on genetics unravels one of the most important breakthroughs in modern science and medicine. IIf our genes are, to a great extent, our destiny, then what would happen if mankind could engineer and alter the very essence of our DNA coding? Millions might be spared the devastating effects of hereditary disease or the challenges of disability, whether it was the pain of sickle-cell anemia to the ravages of Huntington’s disease. But this power to “play God” also raises major ethical questions and poses threats for potential misuse. For decades, these questions have lived exclusively in the realm of science fiction, but as Kevin Davies powerfully reveals in his new book, this is all about to change. Engrossing and page-turning, Editing Humanity takes readers inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code. Davies introduces readers to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale. Though the birth of the “CRISPR babies” in China made international news, there is much more to the story of CRISPR than headlines seemingly ripped from science fiction. In Editing Humanity, Davies sheds light on the implications that this new technology can have on our everyday lives and in the lives of generations to come.

Advances in Animal Biotechnology

Advances in Animal Biotechnology
A Book

by Birbal Singh,Gorakh Mal,Sanjeev K. Gautam,Manishi Mukesh

  • Publisher : Springer
  • Release : 2019-07-09
  • Pages : 562
  • ISBN : 3030213099
  • Language : En, Es, Fr & De
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This book entitled, “Advances in Animal Biotechnology,” is a compilation of state-of-the-art in the field of Animal Biotechnology including fishery, that are not sheltered in depth in earlier publications. It offers an update on avant-garde technologies and advances in key aspects of genetic engineering, metagenomics, assisted reproduction, animal genomics, biotechnology in veterinary health, as well as the role of gut and marine microbial ecosystems in livestock and industrial development. The book is divided broadly into five different sections, viz., Gut Microbiome and Nutritional Biotechnology, Assisted Reproduction Biotechnology, Livestock Genomics, Health Biotechnology, and Animal Biotechnology in Global Perspective. The book covers the syllabi of Animal Biotechnology courses in various universities, academia and competitive examinations at various levels. Researchers, Continuing Graduates, and Academicians, Research Institutions, and Biotech Companies will be benefited from this valuable compilation of research. Its broad spectrum makes this work a valuable resource for professionals, researchers, academics and students in the field of veterinary and animal production as well as the biotechnology industry.

Genetics and Breeding for Disease Resistance of Livestock

Genetics and Breeding for Disease Resistance of Livestock
A Book

by Aruna Pal,A. K. Chakravarty

  • Publisher : Academic Press
  • Release : 2019-10-22
  • Pages : 384
  • ISBN : 0128172673
  • Language : En, Es, Fr & De
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Genetics and Breeding for Disease Resistance of Livestock is a solid resource that combines important information on the underlying genetic causes and governing factors for disease resistance in food animals and applications for breeding purposes. It describes genomics at each species level to help researchers and students understand disease resistance and immunology using genomics and its application in breeding for disease resistance. This useful reference makes it easy for readers to understand and undergo further research in immunology and disease resistance for livestock. It includes novel applications and research material that is ideal for students, teachers, academicians and researchers. Presents basic principles and protocols to describe research methodologies through diagrammatic illustrations with figures, flow charts, examples, and references Covers various disease occurrences in livestock and the methodologies available to identify the various pathogens responsible for these diseases Includes advanced breeding techniques and practical applications

A Crack in Creation

A Crack in Creation
Gene Editing and the Unthinkable Power to Control Evolution

by Jennifer A. Doudna,Samuel H. Sternberg

  • Publisher : Houghton Mifflin Harcourt
  • Release : 2017-06-13
  • Pages : 320
  • ISBN : 0544716965
  • Language : En, Es, Fr & De
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BY THE WINNER OF THE 2020 NOBEL PRIZE IN CHEMISTRY Finalist for the Los Angeles Times Book Prize “The future is in our hands as never before, and this book explains the stakes like no other.” — George Lucas “Required reading for every concerned citizen.” — New York Review of Books Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. That is, until 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the gene-editing tool CRISPR—a revolutionary new technology that she helped create—to make heritable changes in human embryos. The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers. Yet even the tiniest changes to DNA could have myriad, unforeseeable consequences, to say nothing of the ethical and societal repercussions of intentionally mutating embryos to create “better” humans. Writing with fellow researcher Sam Sternberg, Doudna—who has since won the Nobel Prize for her CRISPR research—shares the thrilling story of her discovery and describes the enormous responsibility that comes with the power to rewrite the code of life. “An invaluable account . . . We owe Doudna several times over.” — Guardian

Utilisation and conservation of farm animal genetic resources

Utilisation and conservation of farm animal genetic resources
A Book

by Kor Oldenbroek

  • Publisher : Wageningen Academic Publishers
  • Release : 2007-01-29
  • Pages : 232
  • ISBN : 908686032X
  • Language : En, Es, Fr & De
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www.wageningenacademic.com/geneticresources

Advances in Genome Editing

Advances in Genome Editing
A Book

by Jennifer A. Doudna

  • Publisher : Unknown Publisher
  • Release : 2016
  • Pages : 329
  • ISBN : 9781618962331
  • Language : En, Es, Fr & De
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CRISPR in Animals and Animal Models

CRISPR in Animals and Animal Models
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2017-11-10
  • Pages : 148
  • ISBN : 0128125071
  • Language : En, Es, Fr & De
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CRISPR in Animals and Animal Models, Volume 152, the latest release in the Progress in Molecular Biology and Translational Science series, explores the genome editing CRISPR system in cells and animal models, its applications, the uses of the CRISPR system, and the past, present and future of CRISPR genome editing. Topics of interest in this updated volume include a section on CRISPR history, The genome editing revolution, Programming CRISPR and its applications, CRISPR Delivery methods, CRISPR libraries and screening, CRISPR investigation in haploid cells, CRISPR in the generation of transgenic animals, CRISPR therapeutics, and Promising strategies and present challenges. Accessible to students and researchers alike Written by leading authorities in the field

CRISPR-Cas Systems

CRISPR-Cas Systems
RNA-mediated Adaptive Immunity in Bacteria and Archaea

by Rodolphe Barrangou,John van der Oost

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-13
  • Pages : 302
  • ISBN : 364234657X
  • Language : En, Es, Fr & De
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CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of the art in this exciting field.