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Handbook of Magnetic Resonance Spectroscopy In Vivo

Handbook of Magnetic Resonance Spectroscopy In Vivo
MRS Theory, Practice and Applications

by Paul A. Bottomley,John R. Griffiths

  • Publisher : John Wiley & Sons
  • Release : 2016-10-19
  • Pages : 1232
  • ISBN : 1118997697
  • Language : En, Es, Fr & De
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This handbook covers the entire field of magnetic resonance spectroscopy (MRS), a unique method that allows the non-invasive identification, quantification and spatial mapping of metabolites in living organisms–including animal models and patients. Comprised of three parts: Methodology covers basic MRS theory, methodology for acquiring, quantifying spectra, and spatially localizing spectra, and equipment essentials, as well as vital ancillary issues such as motion suppression and physiological monitoring. Applications focuses on MRS applications, both in animal models of disease and in human studies of normal physiology and disease, including cancer, neurological disease, cardiac and muscle metabolism, and obesity. Reference includes useful appendices and look up tables of relative MRS signal-to-noise ratios, typical tissue concentrations, structures of common metabolites, and useful formulae. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of Magnetic Resonance) publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this handbook and the complete content of eMagRes at your fingertips! Visit the eMagRes Homepage

In-Vivo Magnetic Resonance Spectroscopy II: Localization and Spectral Editing

In-Vivo Magnetic Resonance Spectroscopy II: Localization and Spectral Editing
A Book

by M. Rudin

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 296
  • ISBN : 3642772080
  • Language : En, Es, Fr & De
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Localization 1. C.S. Bosch, J.J.H. Ackerman, St. Louis, MO/USA SurfaceCoil Spectroscopy 2. P. Styles, Oxford, UK Rotating Frame Spectroscopyand Spectroscopic Imaging 3. P.A. Bottomley, Schenectady, NY/USA DepthResolved Surface Coil Spectroscopy (Dress) 4. R.J. Ordidge, J.A. Helpern, Detroit, MI/USA Image Guided Volume Selective Spectroscopy: A Comparison of Techniques for In-Vivo 31P NMR Spectroscopy of Human Brain 5. M. Decorps, D. Bourgeois, Grenoble, France Localized Spectroscopy Using Static Magnetic Field Gradients: Comparison of Techniques 6. J.A. den Hollander, P.R. Luyten, Ad J.H. Marien, Best, The Netherlands 1H NMR Spectroscopy and Spectroscopic Imaging of the Human Brain Spectral Editing and Kinetic Measurements 7. H.P. Hetherington, Birmingham, AL/USA Homo- and Heteronuclear Editing in Proton Spectroscopy 8. D. Freeman, R. Hurd, Fremont, CA/USA Metabolite Specific Methods Using Double Quantum Coherence Transfer Spectroscopy 9. B.A. Berkowitz, Research Triangle Park, NC/USA Two-Dimensional Correlated Spectroscopy In-Vivo 10. G. Navon, Tel Aviv, Israel; T. Kushnir, Tel Hashomer, Israel; N. Askenasy, O. Kaplan, Tel Aviv, Israel Two-Dimensional 31P-1H Correlation Spectroscopy in Intact Organs and Their Extracts 11. M. Rudin, A. Sauter, Basel, Switzerland Measurement of Reaction Rates In Vivo Using Magnetization Transfer Techniques.

Nuclear Magnetic Resonance Spectroscopy of Boron Compounds

Nuclear Magnetic Resonance Spectroscopy of Boron Compounds
A Book

by Heinrich Nöth,Bernd Wrackmeyer

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 464
  • ISBN : 3642667570
  • Language : En, Es, Fr & De
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The revolutionary impetus of the NMR methods in organic chemistry has parallels in the field of boron chemistry. lIB NMR spectroscopy provided a basis for the elucida tion of structures and reactions of the boron hydrides. However, although many studies have been carried out with the higher boranes, carboranes, metalloboranes, etc. , and although certain patterns have emerged, the correlation between the observed chemical shift and the assigned structural unit is still not fully understood. Therefore, predictions in this area are still rather limited, and semiquantitative interpretations are not yet pos sible. Several years ago Eaton and Lipscomb sUpImarized the status in this field in their book "NMR Studies of Boron Hydrides and Related Compounds" and a plethora of new data has accumulated since then. The book also contained material on simple bo rane derivatives, but they were not discussed in any detail. On the other hand many systematic studies, both synthetic and spectroscopic, have been conducted on these simple boron materials in the last decade. Thus a large amount of NMR information is available, not only on lIB but also on 1 H, 1 3 C, and 14 N. However, this information is widely scattered in the literature, and often the data are not discussed at all. It see med appropriate, therefore, to collect these data and to present them in one volume.

Magnetic Resonance Spectroscopy

Magnetic Resonance Spectroscopy
A Book

by Dong-Hyun Kim

  • Publisher : BoD – Books on Demand
  • Release : 2012-03-02
  • Pages : 276
  • ISBN : 9535100653
  • Language : En, Es, Fr & De
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Magnetic Resonance Spectroscopy (MRS) is a unique tool to probe the biochemistry in vivo providing metabolic information non-invasively. Applications using MRS has been found over a broad spectrum in investigating the underlying structures of compounds as well as in determining disease states. In this book, topics of MRS both relevant to the clinic and also those that are beyond the clinical arena are covered. The book consists of two sections. The first section is entitled 'MRS inside the clinic' and is focused on clinical applications of MRS while the second section is entitled 'MRS beyond the clinic' and discusses applications of MRS in other academic fields. Our hope is that through this book, readers can understand the broad applications that NMR and MRS can offer and also that there are enough references to guide the readers for further study in this important topic.

Nuclear Magnetic Resonance Spectroscopy

Nuclear Magnetic Resonance Spectroscopy
A Book

by Frank A. Bovey,Lynn Jelinski,Peter A. Mirau,H. S. Gutowsky

  • Publisher : Academic Press
  • Release : 1988-10-12
  • Pages : 653
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Nine chapters cover: fundamental principles; experimental methods; the chemical shift; coupling of nuclear spins; nuclear relaxation and chemical rate processes; two-dimensional nuclear magnetic resonance spectroscopy; macromolecules; NMR of solids; special topics. Annotation copyrighted by Book News, Inc., Portland, OR

Clinical Magnetic Resonance Spectroscopy

Clinical Magnetic Resonance Spectroscopy
A Book

by E.B. Cady

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 290
  • ISBN : 1468413333
  • Language : En, Es, Fr & De
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Nobody can know everything. For the successful application of techniques based on nuclear magnetic resonance to clinical problems, it is a vital necessity that individuals with widely different skills should learn a little of each others' trades by co-operation and communication. Ernest Cady has long proved himself a master of these arts to his colleagues at University College London, and by writing this excellent book he extends his experience to a wide circle of readers. Although the nuclear magnetic resonance (NMR) phenomenon had been predicted theoretically (and to some degree demonstrated experimentally) appreciably earlier, it required the advances in electronics that took place during World War II to turn NMR into a practical technique, as demonstrated independently in 1946 by Bloch and Purcell. Since then, NMR has been used extensively and increasingly by chemists and physicists. In the 1970s the first applications of NMR to animal organs yielded important advances in our knowledge of the biochemical and physiological processes as they occur in genuinely intact tissues. They showed incidentally that some conventional techniques introduce significant artifacts.

Nuclear Magnetic Resonance Spectroscopy of Cement-Based Materials

Nuclear Magnetic Resonance Spectroscopy of Cement-Based Materials
A Book

by Pierre Colombet,Arnd-Rüdiger Grimmer,Helene Zanni,Piero Sozzani

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 430
  • ISBN : 3642804322
  • Language : En, Es, Fr & De
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NMR spectroscopy has become one of the most powerful methods for the study of the structure and dynamics of solid-state materials. NMR has thus become an important tool, not only in the study of existent cements, but also in the development of new cement-based materials. This volume, based on the proceedings of the second international conference on the NMR Spectroscopy of Cement Based Materials held in Bergamo, Italy, in June 1996, presents the only international overview of the state of the art in the use of NMR in the study of cement-based materials. - This book is of particular interest to all those working in the areas of cement science, material science, solid state chemsitry, analytical chemistry, spectroscopy and those areas of physics engaged in the study of materials.

Magnetic Resonance Spectroscopy and Imaging in Neurochemistry

Magnetic Resonance Spectroscopy and Imaging in Neurochemistry
A Book

by Herman Bachelard

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 413
  • ISBN : 1461558638
  • Language : En, Es, Fr & De
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The Advances in Neurochemistry series was initiated for a readership of neuroscientists with a background in biochemistry. True to this concept, the present volume brings together various applications of magnetic resonance technology to advance our knowledge of how the nervous system functions. Whether at the cellular, tissue slice, or intact organism level. magnetic resonance techniques are by their nature noninvasive, and thus provide a window through which biochemical reactions can be viewed without grinding, binding, or other wise perturbing ongoing physiological processes. As technological improve ments in methodology, such as higher and more uniform magnetic fields, novel paradigms for data analysis, etc. , are made, we find increased sensitivity and improved temporal and spatial resolution for functional imaging techniques on the one hand, and better separation of signals that identify chemical properties in spectral shift studies, on the other. It is upon knowledge such as is described in the twelve chapters that follow, that further advances in scientific discovery and the biomedical applications of tomorrow will be based. We are grateful to Dr. Bachelard, the Volume Editor, and to the authors of the individual chapters for their efforts. We also note that with this volume Dr. Morris Aprison, a co-founder of the Advances in Neurochemistry series has stepped down and acknowledge with thanks his major role in its inception. In addition, we thank our past and present Advisory Editors. Bernard W. Agranoff Kunihiko Suzuki Series Editors ix CONTENTS LIST OF SYMBOLS AND GLOSSARY . . . . . . . . . . . . . . . . . . . . . . . . . . . XXI INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Nuclear Magnetic Resonance Spectroscopy in the Study of Neoplastic Tissue

Nuclear Magnetic Resonance Spectroscopy in the Study of Neoplastic Tissue
A Book

by Raffaella Tosi

  • Publisher : Nova Publishers
  • Release : 2005
  • Pages : 444
  • ISBN : 9781594542589
  • Language : En, Es, Fr & De
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Carbon-13 Nuclear Magnetic Resonance Spectroscopy

Carbon-13 Nuclear Magnetic Resonance Spectroscopy
A Book

by George C. Levy,George C. Nelson,Robert L. Lichter,Gordon L. Nelson,Dean College of Science and Liberal Arts Gordon L Nelson

  • Publisher : Unknown Publisher
  • Release : 1980-08-21
  • Pages : 338
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The expanded, updated edition, covering basic theoretical and experimental concepts and an overall view of 13C spectral characteristics; 13C methods, results, and applications for aliphatic and aromatic compounds, functional groups, organic intermediates, and organometallic compounds; 13C nmr of synthetic high-molecular-weight polymers; relaxation processes; applications to natural products and biopolymers; and special methods and applications. Contains over 1,000 references, extensive tables, illustrations, and problems with answers.

Applications of Nuclear Magnetic Resonance Spectroscopy in Organic Chemistry

Applications of Nuclear Magnetic Resonance Spectroscopy in Organic Chemistry
A Book

by L. M. Jackman,S. Sternhell

  • Publisher : Elsevier
  • Release : 2013-10-22
  • Pages : 474
  • ISBN : 1483280942
  • Language : En, Es, Fr & De
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Application of Nuclear Magnetic Resonance Spectroscopy in Organic Chemistry, Second Edition covers the theoretical background necessary for the intelligent application of NMR spectroscopy to common problems encountered in organic chemistry. This book is composed of five parts, and begins with introduction to the theory and practice of nuclear magnetic resonance. The succeeding chapter deals with the theory of chemical effects in NMR spectroscopy. These topics are followed by a discussion on the application of chemical shift to organic compound analysis and the principles of the spin-spin coupling .The final chapter considers the applications of time- dependent phenomena in NMR spectroscopy. This book will prove useful to analytical chemists and researchers in the allied fields.

Progress in Nuclear Magnetic Resonance Spectroscopy

Progress in Nuclear Magnetic Resonance Spectroscopy
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1971
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Nuclear Magnetic Resonance Spectroscopy

Nuclear Magnetic Resonance Spectroscopy
An Introduction to Principles, Applications, and Experimental Methods

by Joseph B. Lambert,Eugene P. Mazzola,Clark D. Ridge

  • Publisher : Wiley
  • Release : 2019-01-04
  • Pages : 480
  • ISBN : 1119295238
  • Language : En, Es, Fr & De
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Combines clear and concise discussions of key NMR concepts with succinct and illustrative examples Designed to cover a full course in Nuclear Magnetic Resonance (NMR) Spectroscopy, this text offers complete coverage of classic (one-dimensional) NMR as well as up-to-date coverage of two-dimensional NMR and other modern methods. It contains practical advice, theory, illustrated applications, and classroom-tested problems; looks at such important ideas as relaxation, NOEs, phase cycling, and processing parameters; and provides brief, yet fully comprehensible, examples. It also uniquely lists all of the general parameters for many experiments including mixing times, number of scans, relaxation times, and more. Nuclear Magnetic Resonance Spectroscopy: An Introduction to Principles, Applications, and Experimental Methods, 2nd Edition begins by introducing readers to NMR spectroscopy - an analytical technique used in modern chemistry, biochemistry, and biology that allows identification and characterization of organic, and some inorganic, compounds. It offers chapters covering: Experimental Methods; The Chemical Shift; The Coupling Constant; Further Topics in One-Dimensional NMR Spectroscopy; Two-Dimensional NMR Spectroscopy; Advanced Experimental Methods; and Structural Elucidation. Features classical analysis of chemical shifts and coupling constants for both protons and other nuclei, as well as modern multi‐pulse and multi-dimensional methods Contains experimental procedures and practical advice relative to the execution of NMR experiments Includes a chapter-long, worked-out problem that illustrates the application of nearly all current methods Offers appendices containing the theoretical basis of NMR, including the most modern approach that uses product operators and coherence-level diagrams By offering a balance between volumes aimed at NMR specialists and the structure-determination-only books that focus on synthetic organic chemists, Nuclear Magnetic Resonance Spectroscopy: An Introduction to Principles, Applications, and Experimental Methods, 2nd Edition is an excellent text for students and post-graduate students working in analytical and bio-sciences, as well as scientists who use NMR spectroscopy as a primary tool in their work.

Nuclear Magnetic Resonance Spectroscopy of Nuclei Other Than Protons

Nuclear Magnetic Resonance Spectroscopy of Nuclei Other Than Protons
A Book

by T. Axenrod,Graham Alan Webb

  • Publisher : Unknown Publisher
  • Release : 1974
  • Pages : 407
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Nuclear Magnetic Resonance Spectroscopy

Nuclear Magnetic Resonance Spectroscopy
A Book

by John Henry Nelson

  • Publisher : Pearson College Division
  • Release : 2003
  • Pages : 464
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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This is the only how-to volume that investigates the spectroscopy of a variety of nuclides other than H and C in depth. It contains extensive reference material and numerous problems, most of which include real spectra. It is written to provide users with the knowledge necessary to choose the most appropriate experiment to obtain the best quality spectra with the ability to fully interpret the data. The book covers basic theory of NMR spectroscopy, spectrum measurement, the chemical shift and examples for selected nuclei, symmetry and NMR spectroscopy, spin-spin coupling and NMR spin systems, typical magnitude of selected coupling constants, nuclear spin relaxation, the nuclear overhauser effect, editing C NMR spectra, two-dimensional NMR spectroscopy, dynamic NMR spectroscopy, lanthanide shift reagents (LSR), NMR of solids. For NMR spectroscopists and analytical chemists.

In-Vivo Magnetic Resonance Spectroscopy III: In-Vivo MR Spectroscopy: Potential and Limitations

In-Vivo Magnetic Resonance Spectroscopy III: In-Vivo MR Spectroscopy: Potential and Limitations
A Book

by Anonim

  • Publisher : Springer
  • Release : 2011-12-16
  • Pages : 190
  • ISBN : 9783642772207
  • Language : En, Es, Fr & De
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Isolated Cells and Perfused Organs 1. O. Kaplan, P.C.M. van Zijl, J.S. Cohen, Washington, DC/USA NMR Studies of Metabolism of Cells and Perfused Organs Individual Nuclei 2. S.R. Williams, London, UK In Vivo Proton Spectroscopy: Experimental Asoects and Potential 3. N. Beckmann, Basel, Switzerland In Vivo 13C Spectroscopy in Humans 4. M.J.W. Prior, R.J. Maxwell, J.R. Griffiths, London, UK Fluorine - 19F NMR Spectroscopy and Imaging In Vivo 5. J.S. Ingwall, Boston, MA/USA Measuring Cation Movements Across the Cell Wall Using NMR Spectroscopy: Sodium Movements in Striated Muscle 6. M. Rudin, A. Sauter, Basel, Switzerland In Vivo Phosphorus-31 NMR: Potential and Limitations

In-Vivo Magnetic Resonance Spectroscopy III: In-Vivo MR Spectroscopy: Potential and Limitations

In-Vivo Magnetic Resonance Spectroscopy III: In-Vivo MR Spectroscopy: Potential and Limitations
A Book

by Markus Rudin

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 190
  • ISBN : 3642772188
  • Language : En, Es, Fr & De
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Isolated Cells and Perfused Organs 1. O. Kaplan, P.C.M. van Zijl, J.S. Cohen, Washington, DC/USA NMR Studies of Metabolism of Cells and Perfused Organs Individual Nuclei 2. S.R. Williams, London, UK In Vivo Proton Spectroscopy: Experimental Asoects and Potential 3. N. Beckmann, Basel, Switzerland In Vivo 13C Spectroscopy in Humans 4. M.J.W. Prior, R.J. Maxwell, J.R. Griffiths, London, UK Fluorine - 19F NMR Spectroscopy and Imaging In Vivo 5. J.S. Ingwall, Boston, MA/USA Measuring Cation Movements Across the Cell Wall Using NMR Spectroscopy: Sodium Movements in Striated Muscle 6. M. Rudin, A. Sauter, Basel, Switzerland In Vivo Phosphorus-31 NMR: Potential and Limitations.

Nuclear Magnetic Resonance Spectroscopy

Nuclear Magnetic Resonance Spectroscopy
A Book

by Anonim

  • Publisher : MDPI
  • Release : 2018-06-13
  • Pages : 308
  • ISBN : 3038429937
  • Language : En, Es, Fr & De
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Nuclear Magnetic Resonance (NMR) spectroscopy is a nondestructive technique that can be used to characterize a wide variety of systems. Sustained development of both methodology and instrumentation have allowed NMR to evolve as a powerful technology, with applications in pure sciences, medicine, drug development, and important branches of industry. NMR provides precise structural information down to each atom and bond in a molecule, and is the only method for the determination of structures of molecules in a solution. This book compiles a series of articles describing the application of NMR in a variety of interesting scientific challenges. The articles illustrate the versatility and flexibility of NMR.

Nuclear Magnetic Resonance Spectroscopy of Adsorbed Species on Molybdenum Nitride

Nuclear Magnetic Resonance Spectroscopy of Adsorbed Species on Molybdenum Nitride
A Book

by Grant Wesley Haddix

  • Publisher : Unknown Publisher
  • Release : 1988
  • Pages : 380
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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High Resolution Nuclear Magnetic Resonance Spectroscopy

High Resolution Nuclear Magnetic Resonance Spectroscopy
A Book

by J. W. Emsley,J Feeney,L H Sutcliffe

  • Publisher : Elsevier
  • Release : 2013-10-22
  • Pages : 542
  • ISBN : 1483184080
  • Language : En, Es, Fr & De
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High Resolution Nuclear Magnetic Resonance Spectroscopy, Volume 2 provides a comprehensive coverage of the theories and methods for analysis of high resolution spectra. The title also presents a discourse on other variables that affect the spectra. The text first details the correlations of 1H resonance spectral parameters with molecular structure, and then proceeds to tackling the 19F nuclear magnetic resonance studies. Next, the selection deals with the NMR spectra of nuclei other than hydrogen fluoride. The text also provides data sets, such as nuclear properties, T-values, and chemical shifts. The book will be of great use to scientists who utilize nuclear magnetic resonance in their work.