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Managing Health in the Genomic Era

Managing Health in the Genomic Era
A Guide to Family Health History and Disease Risk

by Vincent Henrich,Lori A. Orlando,Brian H. Shirts

  • Publisher : Academic Press
  • Release : 2020-06-27
  • Pages : 238
  • ISBN : 0128160160
  • Language : En, Es, Fr & De
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In Managing Health in the Genomic Era: A Guide to Family Health History and Disease Risk, Drs. Vincent C. Henrich, Lori A. Orlando, and Brian H. Shirts discuss the practical considerations surrounding the use of genomic and genetic tests to manage patient health, to provide adult disease risk assessment, to improve diagnosis, and to support effective interventions and treatment. In 10 chapters, evidence-based information and case studies are described and examine the central place of family health history (FHH) in genomic medicine, tools and strategies for compiling and analyzing family health history, how to identify existing and novel genetic markers, how to identify lineage specific (or rare) variants within families, and how to find effective interventions based on genetic testing results and FHH. Factors that influence clinical practice, including gene-environment interactions, FHH social networking, direct to consumer (DTC) genetic testing and data sharing, algorithms for analyzing genetic data, and patient counseling are discussed from the standpoint of clinical practice. Here, frontline healthcare providers will discover succinct commentary and key examples to assist with their local needs. Relevant principles of genetic biology and inheritance are explored and guidance on available support networks and online resources is also provided Presents a practical, accessible resource for primary care providers, allied health professionals, pharmacologists, public health professionals, students and clinical researchers Addresses genetic and genomic approaches in managing patient health, conducting and analyzing family health histories, and assessing adult disease risk Features an expert author team with direct experience integrating genetics and genomics in primary care and family medicine settings Examines the attributes and limitations of family health history, genetic testing, and genomic testing in clinical practice Includes detailed explanations following practice-based examples

Managing biomedical research to prevent and cure disease in the 21st century

Managing biomedical research to prevent and cure disease in the 21st century
matching NIH policy with science : joint hearing before the Committee on Energy and Commerce, House of Representatives, and the Committee on Health, Education, Labor, and Pensions, U.S. Senate, One Hundred Eighth Congress, first session, October 2, 2003

by United States. Congress. House. Committee on Energy and Commerce

  • Publisher : Unknown Publisher
  • Release : 2004
  • Pages : 260
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Nursing Care in the Genomic Era

Nursing Care in the Genomic Era
A Case-based Approach

by Jean F. Jenkins,Dale Halsey Lea

  • Publisher : Jones & Bartlett Learning
  • Release : 2005
  • Pages : 411
  • ISBN : 9780763733254
  • Language : En, Es, Fr & De
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Increasingly, genomic-based approaches and resources are redefining our categorization of disease, leading to new approaches to prevention and therapy. As nurses traditionally practice patient-oriented care, they will undoubtedly play a key role in both developing and applying the aspects of genomic health care. Nursing Care in the Genomic Era: A Case Based Approach is designed to provide nurses with up-to-date and accessible information on this powerful new approach to understanding, preventing, and treating disease.The framework for each chapter consists of core competencies in genetics, interwoven with stories that highlight a particular condition and the related biological, personal, and psychosocial issues. The chapters then go on to address the knowledge, skills, and attitudes necessary for nurses and health professionals as recommended by the National Coalition for Health Professional Education in Genetics (NCHPEG). The text presents the genetic components of common diseases such as cancer, diabetes, heart disease, and Alzheimer's, and the innovative technologies used to detect them.Understanding genomic issues and how they affect individuals and families is the first step for nurses hoping to make a difference when providing nursing care in the genomic era.

Renaissance of Sickle Cell Disease Research in the Genome Era

Renaissance of Sickle Cell Disease Research in the Genome Era
A Book

by Betty S Pace

  • Publisher : World Scientific
  • Release : 2007-01-24
  • Pages : 396
  • ISBN : 1908979917
  • Language : En, Es, Fr & De
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The Human Genome Project has spawned a Renaissance of research faced with the daunting expectation of personalized medicine for individuals with sickle cell disease in the Genome Era. This book offers a comprehensive and timeless account of emerging concepts in clinical and basic science research, and community concerns of health disparity to educate professionals, students and the general public about meeting this challenging expectation. Contributions from physicians, research scientists, scientific administrators and community workers make Renaissance of Sickle Cell Disease Research in the Genome Era unique among the catalogue of books on this genetic disorder. Part 1 offers detailed review of the National Heart Lung and Blood Institute's leadership role in funding sickle cell research, as well as developing progressive research initiatives and the predicted impact of the Human Genome Project. Part 2 gives an account of several clinical research perspectives based on the Cooperative Study of Sickle Cell Disease. These include recommendations for newborn screening, pain management, stroke, transfusion therapy and pediatric and adult healthcare. Part 3 offers novel insights into basic science research progress and the impact of the Human Genome Project on the direction of hemoglobinopathy research, including hemoglobin switching, bone marrow transplantation and gene therapy. Part 4 engages the reader in a culture-based discussion of the stigma attached to sickle cell disease in the African American community and the apprehensions about genetic research in this community. It concludes with a global perspective on sickle cell disease from African, European and American experiences. For readers seeking a definitive account of sickle cell disease appropriate for students, researchers and community workers, this collaborative effort is an ideal textbook. Contents:Sickle Cell Disease: Demystifying the Beginnings (C Reid & G Rodgers)Sponsorship of Sickle Cell Disease Research by the National Institutes of Health: A Brief History and Projections for the Future (G L Evans & D G Badman)The Human Genome Project (B S Pace)Sickle Cell Disease: A Phenotypic Patchwork (K Smith-Whitley & B S Pace)Preventive Care and Advances in the Treatment of Sickle Cell Disease (C T Quinn & G R Buchanan)Sickle Cell Disease in Adults (J Haynes, Jr. & A Pack-Mabien)Pain in Sickle Cell Disease: A Multidimensional Construct (L J Benjamin & R Payne)Transfusion Therapy in Sickle Cell Disease (C Hoppe et al.)Hemoglobin S Polymerization, Just the Beginning (F A Ferrone)Damage to the Red Blood Cell Membrane in Sickle Cell Disease (S R Goodman & C Joiner)Fetal Hemoglobin for What Ails Sickle Hemoglobin (S F Ofori-Acquah & B S Pace)Genetic Modulation of Sickle Cell Disease (M H Steinberg & L T Swee)Molecular Framework of Hemoglobin Switching (S Fiering)Dynamic Nucleoprotein Structure of the ß-Globin Locus: Establishing a Rational Molecular Basis for the Therapeutic Modulation of Hemoglobin Switching (E Bresnick et al.)Vertebrate Models for Sickle Cell Disease Research (B H Paw et al.)Stem Cell Biology (W Li & A W Flake)Bone Marrow Transplantation (R I Raphael & M C Walters)Genetically Engineered Cures: Gene Therapy for Sickle Cell Disease (P Malik & P Leboulch)Sickle Cell Disease: The Past, Present and Future Social and Ethical Dilemmas (V L Bonham, Jr. et al.)It Takes a Village to Cure Sickle Cell Disease (R Peterson & D Davis-Maye)Beyond National Borders: A Global Perspective on Advances in Sickle Cell Disease Research and Management, and New Challenges in the Genome Era (S F Ofori-Acquah & K Ohene-Frempong) Readership: Primary market: Clinical and basic researchers in haematology and genetics, graduate students and postdoctoral fellows; Secondary market: Nursing students, community sickle cell programs, medical school libraries, public library; Tertiary market: Suitable for a graduate course in genetics, genomics as a supplemental text, probably not a primary text. Keywords:Sickle Cell Anemia/Disease;Genomic Era;National Heart Lung and Blood Institute;National Institute of Diabetes and Digestive and Kidney Diseases;Stroke;Pain Management;Fetal Hemoglobin;Hemoglobin Switching;Transgenic Mouse Model;Locus Control Region;African-American Community;Sickle Cell Africa;World Health OrganizationKey Features:Covers the latest progress made in clinical, basic and social research of SCDCaptures the momentum of research efforts related to SCD; this is very timely in light of the plan to perform the first gene therapy treatment in 2006Five out of ten of the current Directors of the National Heart, Lung, and Blood Institute (NHLBI)-funded Comprehensive Sickle Cell Centers are amongst the prominent contributors to the book. These clinical and basic researchers have a major influence in shaping the future focus of programs for sickle cell disease in the United States

Plant Disease Management in the Post-Genomic Era: From Functional Genomics to Genome Editing

Plant Disease Management in the Post-Genomic Era: From Functional Genomics to Genome Editing
A Book

by Sabrina Sarrocco,Alfredo Herrera-Estrella,David B. Collinge

  • Publisher : Frontiers Media SA
  • Release : 2020-03-16
  • Pages : 329
  • ISBN : 2889635600
  • Language : En, Es, Fr & De
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Handbook of Pharmaceutical Biotechnology

Handbook of Pharmaceutical Biotechnology
A Book

by Shayne C. Gad

  • Publisher : Wiley-Interscience
  • Release : 2007-06-11
  • Pages : 1659
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Describes the use of biotechnology to develop pharmaceuticals. This book gives the professional a basic tool to facilitate the development of biotech medicines by bringing together a general overview of biotechnology used in the drug development process, along with a compendium of regulations and validation methods.

The Clinical Practice of Neurological and Neurosurgical Nursing

The Clinical Practice of Neurological and Neurosurgical Nursing
A Book

by Joanne V. Hickey

  • Publisher : Lippincott Williams & Wilkins
  • Release : 2009
  • Pages : 768
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The new Sixth Edition of this award-winning classic prepares its users for delivering expert care in this most challenging nursing specialty. It addresses neuroanatomy, assessment, diagnostic evaluation, and management of the complete range of neurological disorders for which nurses provide patient care, including trauma, stroke, tumors, seizures, headache, aneurysms, infections, degenerative disorders, and peripheral neuropathies. This edition has been thoroughly revised to reflect standards of care based on evidence-based practice. It now includes case studies, community nursing sections throughout, and increased coverage of normal pressure hydrocephalus, inflammatory demyelinating polyneuropathy, and Creutzfeld-Jacob disease.

The Moral, Social, and Commercial Imperatives of Genetic Testing and Screening

The Moral, Social, and Commercial Imperatives of Genetic Testing and Screening
The Australian Case

by Michela Betta

  • Publisher : Springer Science & Business Media
  • Release : 2006-07-14
  • Pages : 268
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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This is a dynamic book that successfully combines global and local thinking with regard to an emerging technology that will contribute to the expansion of proteomics and pharmacogenomics, the science of tailored healthcare and treatments. Genetic testing and screening will change the way people understand health, diagnostic knowledge, illness but also crime, databases and private information, paternity, and self-knowledge. In addition to giving individuals the opportunity to think differently about their well-being, it installs a new taxonomy in terms of illness, because its probabilistic effects will introduce a new narrative in the health discourse of 21st century society. While in the past people could be classified as being healthy or sick, now, through genetic testing and screening, adults can be classified as being healthy, predisposed to an illness, probably at risk, at risk, or carriers of certain risks. The effects of this taxonomy do not remain confined to the individual who is tested but extends to an entire family, as genetic knowledge is family knowledge. But the technology of genetic testing and screening installs a second dramatic register in the prenatal phase when cells and embryos are tested and subsequently altered in order to hit targets of perfection. However, this technology can also be seen as a strategy for the acquisition of new knowledge about oneself, as it instigates a different attitude towards ourselves in a scenario in which the notion of life as a singular noun is seriously questioned by cultural practices that make it necessary to speak of forms of life. The complexity of the Self resulting from this epistemological shift evoke the ancient Greco-roman practices of the care of the self leading to self-knowledge. Genetic testing and screening could therefore be understood as a form of self-quest, and attempt to discover what we are beyond our wishes and desires - beyond what we would like to be.

Environment, Agroforestry & Livestock Management

Environment, Agroforestry & Livestock Management
A Book

by S. S. Kundu

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 700
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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By the turn of the twenty-first century, there lies a possible threat due to atmospheric pollution, change in global climate, depletion of aquifers, per capita shrinking of cropland, collapsing ecosystems. For an evergreen agriculture, agro forestry and livestock production through scientific management possibly deserves a trial with hitherto adopted policy, skewed for crop production.

Cancer Informatics in the Post Genomic Era

Cancer Informatics in the Post Genomic Era
Toward Information-Based Medicine

by Igor Jurisica,Dennis A. Wigle,Bill Wong

  • Publisher : Springer Science & Business Media
  • Release : 2007-05-04
  • Pages : 180
  • ISBN : 0387693211
  • Language : En, Es, Fr & De
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Cancer Informatics in Post-Genomic Era provides both the necessary methodology and practical information tools for analyzing data in the field of medical information science. This, of course, requires analytic tools. Those tools are garnered by developing and assessing methods and systems for the acquisition, processing, and interpretation of patient data, aided by scientific discovery. Key challenges in this field include integrating research and clinical care, sharing data, and establishing partnerships within and across sectors of patient diagnosis and treatment.

EAdoption and the Knowledge Economy

EAdoption and the Knowledge Economy
Issues, Applications, Case Studies

by Paul M. Cunningham

  • Publisher : Unknown Publisher
  • Release : 2004
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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American Journal of Health Education

American Journal of Health Education
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2007
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Section Newsletters

Section Newsletters
A Book

by Association of American Law Schools

  • Publisher : Unknown Publisher
  • Release : 2001
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Policy & Politics in Nursing and Health Care

Policy & Politics in Nursing and Health Care
A Book

by Diana J. Mason,Judith Kline Leavitt,Mary W. Chaffee

  • Publisher : Saunders
  • Release : 2007
  • Pages : 1066
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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This volume enables readers to analyse policy issues, enhance their political knowledge and skills and prepare for leadership roles in policy-making and public health. It cultivates the development of valuable skills including political and policy analysis, conflict management, lobbying, and more.

The First Wealth is Health

The First Wealth is Health
The Nexus of Health, Poverty, and the Law : Symposium Issue

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2009
  • Pages : 307
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Mechanism of Fertilization--plants to Humans

Mechanism of Fertilization--plants to Humans
A Book

by Brian Dale

  • Publisher : Springer Verlag
  • Release : 1990
  • Pages : 708
  • ISBN : 9780387517667
  • Language : En, Es, Fr & De
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CORDIS Focus

CORDIS Focus
RTD results supplement

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2006
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Healthcom 2003

Healthcom 2003
Proceedings, 5th International Workshop on Enterprise Networking and Computing in Healthcare Industry, June 6-7, 2003, Santa Monica, CA, USA

by Anonim

  • Publisher : Institute of Electrical & Electronics Engineers(IEEE)
  • Release : 2003
  • Pages : 162
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Integrated Operations Management

Integrated Operations Management
A Supply Chain Perspective

by Mark D. Hanna,W. Rocky Newman

  • Publisher : South-Western Pub
  • Release : 2007
  • Pages : 873
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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With its focus on supply chain management and the increased blending of service theory and applications with traditional manufacturing theory and applications, INTEGRATED OPERATIONS MANAGEMENT: A SUPPLY CHAIN PERSPECTIVE ties together SCM, business process management, with cross functional understanding. The authors cover creating processes, coordinating processes, and improving processes.

C D A Journal

C D A Journal
A Book

by California Dental Association

  • Publisher : Unknown Publisher
  • Release : 1998
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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