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Managing the Drug Discovery Process

Managing the Drug Discovery Process
How to Make It More Efficient and Cost-Effective

by Walter Moos,Susan Miller,Stephen Munk,Barbara Munk

  • Publisher : Woodhead Publishing
  • Release : 2016-11-08
  • Pages : 536
  • ISBN : 0081006322
  • Language : En, Es, Fr & De
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Managing the Drug Discovery Process: How to Make It More Efficient and Cost-Effective thoroughly examines the current state of pharmaceutical research and development by providing chemistry-based perspectives on biomedical research, drug hunting and innovation. The book also considers the interplay of stakeholders, consumers, and the drug firm with attendant factors, including those that are technical, legal, economic, demographic, political, social, ecological, and infrastructural. Since drug research can be a high-risk, high-payoff industry, it is important to researchers to effectively and strategically manage the drug discovery process. This book takes a closer look at increasing pre-approval costs for new drugs and examines not only why these increases occur, but also how they can be overcome to ensure a robust pharmacoeconomic future. Written in an engaging manner and including memorable insights, this book is aimed at redirecting the drug discovery process to make it more efficient and cost-effective in order to achieve the goal of saving countless more lives through science. A valuable and compelling resource, this is a must-read for all students and researchers in academia and the pharmaceutical industry. Considers drug discovery in multiple R&D venues, including big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable

Comprehensive medicinal chemistry II

Comprehensive medicinal chemistry II
A Book

by John B. Taylor,D. J. Triggle

  • Publisher : Elsevier Science Ltd
  • Release : 2007
  • Pages : 7200
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The first edition of Comprehensive Medicinal Chemistry was published in 1990 and very well received. Comprehensive Medicinal Chemistry II is much more than a simple updating of the contents of the first edition. Completely revised and expanded, this new edition has been refocused to reflect the significant developments and changes over the past decade in genomics, proteomics, bioinformatics, combinatorial chemistry, high-throughput screening and pharmacology, and more. The content comprises the most up-to-date, authoritative and comprehensive reference text on contemporary medicinal chemistry and drug research, covering major therapeutic classes and targets, research strategy and organisation, high-throughput technologies, computer-assisted design, ADME and selected case histories. It is this coverage of the strategy, technologies, principles and applications of medicinal chemistry in a single work that will make Comprehensive Medicinal Chemistry II a unique work of reference and a single point of entry to the literature for pharmaceutical and biotechnology scientists of all disciplines and for many industry executives as well.Comprehensive Medicinal Chemistry II will be available online in 2007 via the proven platform ScienceDirect providing the user with enhanced features such as cross-referencing and dynamic linking. * Comprehensively reviews - for the first time in one single work - the strategies, technologies, principles and applications of modern medicinal chemistry * Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets * Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs

Integrated Drug Discovery Technologies

Integrated Drug Discovery Technologies
A Book

by Houng-Yau Mei,Anthony W. Czarnik

  • Publisher : CRC Press
  • Release : 2002-03-19
  • Pages : 576
  • ISBN : 082474473X
  • Language : En, Es, Fr & De
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Integrated Drug Discovery Technologies provides a global overview of emerging drug development technologies by presenting and integrating new techniques from the disciplines of chemistry, biology, and computational sciences. It combines integration of contemporary mechanization with strategies in drug delivery. Topics include: functional genomics, microfabrication techniqes, integrated proteomics technologies, high throughput screening, and fluorescence correlation spectroscopy methods.

Drug Discovery and Evaluation: Methods in Clinical Pharmacology

Drug Discovery and Evaluation: Methods in Clinical Pharmacology
A Book

by H.Gerhard Vogel,Jochen Maas,Alexander Gebauer

  • Publisher : Springer Science & Business Media
  • Release : 2010-12-15
  • Pages : 564
  • ISBN : 3540898905
  • Language : En, Es, Fr & De
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Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".

International Journal of Technology Management

International Journal of Technology Management
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1998
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Productivity

Productivity
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2003
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Methods and Techniques in Drug Discovery

Methods and Techniques in Drug Discovery
A Book

by John Sterling,Ellyn J. T. D. Kerr,Shannon Simons

  • Publisher : Unknown Publisher
  • Release : 2005
  • Pages : 266
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Chemical and Engineering News

Chemical and Engineering News
"news Edition" of the American Chemical Society

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1995
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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New Scientist

New Scientist
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Managing the Globalization Process

Managing the Globalization Process
An Exploratory Study : a Thesis

by Thomas W. Malnight

  • Publisher : Unknown Publisher
  • Release : 1992
  • Pages : 714
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Managing High Technology

Managing High Technology
An Interdisciplinary Perspective : Based on Papers from the Third International Conference on Interdisciplinary Research, Seattle, Washington, U.S.A., 1-3 August, 1984

by Brian Wayne Mar,William T. Newell,Börje Osvald Saxberg

  • Publisher : North Holland
  • Release : 1985
  • Pages : 413
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Managing Information

Managing Information
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2003
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Pharmacokinetics

Pharmacokinetics
Processes, Mathematics, and Applications

by Peter G. Welling

  • Publisher : Amer Chemical Society
  • Release : 1997
  • Pages : 393
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Pharmacokinetics is the study of the absorption, distribution, metabolism, and excretion of drugs in humans. This book, written by an internationally known researcher, teaches the basic principles, including drug transport, parenteral and enteral routes of drug administration, and factors affecting drug absorption, distribution, and metabolism. Extensively revised, this edition presents the mathematics of pharmacokinetics with various single- and multi-compartment models including detailed descriptions of metabolite and nonlinear pharmacokinetics. It also describes renal and hepatic drug clearance, and the influence of kidney and liver impairment on these functions. Taking a tutorial approach throughout, the author provides both a clear introduction to pharmacokinetics and a critical look at how this science affects drug discovery and development.

Managing Innovation

Managing Innovation
A Book

by Edwin Austin Gee,Chaplin Tyler

  • Publisher : John Wiley & Sons
  • Release : 1976
  • Pages : 267
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Managing Biotechnology in Drug Development

Managing Biotechnology in Drug Development
A Book

by Chi-Jen Lee

  • Publisher : CRC Press
  • Release : 1996-06-05
  • Pages : 181
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Improve your understanding of biotechnology's impact on drug development, production, and regulation with Managing Biotechnology in Drug Development. This informative book unravels the complex workings of the U.S. Food and Drug Administration's regulatory processes for drugs and biological products, including vaccines and recombinant DNA-derived products. It initially reviews the important role of biotechnology in medicine and the pharmaceutical industry. It then discusses the development of drugs and biologics from a regulatory perspective, spotlights biotechnology management strategies, and examines biotechnology product development by research institutes and the pharmaceutical industry. The book concludes with an insightful exploration of biotechnology's exciting future.

California Management Review

California Management Review
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2014
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Natural Products

Natural Products
Rapid Utilization of Sources for Drug Discovery and Development

by Nancy Mulford,Carol Sussman

  • Publisher : Unknown Publisher
  • Release : 1995
  • Pages : 339
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Management Science

Management Science
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2000
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Issues for Feb. 1965-Aug. 1967 include Bulletin of the Institute of Management Sciences.

Technology Management

Technology Management
A Unifying Discipline for Melting the Boundaries

by Timothy Roy Anderson

  • Publisher : Institute of Electrical & Electronics Engineers(IEEE)
  • Release : 2005
  • Pages : 552
  • ISBN : 9781890843113
  • Language : En, Es, Fr & De
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Pharmaceutical Executive

Pharmaceutical Executive
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1992
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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