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Medical Epigenetics

Medical Epigenetics
A Book

by Trygve Tollefsbol

  • Publisher : Academic Press
  • Release : 2016-06-21
  • Pages : 924
  • ISBN : 0128032405
  • Language : En, Es, Fr & De
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Medical Epigenetics provides a comprehensive analysis of the importance of epigenetics to health management. The purpose of this book is to fill a current need for a comprehensive volume on the medical aspects of epigenetics with a focus on human systems, epigenetic diseases that affect these systems and modes of treating epigenetic-based disorders and diseases. The intent of this book is to provide a stand-alone comprehensive volume that will cover all human systems relevant to epigenetic maladies and all major aspects of medical epigenetics. The overall goal is to provide the leading book on medical epigenetics that will be useful not only to physicians, nurses, medical students and many others directly involved with health care, but also investigators in life sciences, biotech companies, graduate students and many others who are interested in more applied aspects of epigenetics. Research in the area of translational epigenetics is a cornerstone of this volume. Critical reviews dedicated to the burgeoning role of epigenetics in medical practice Coverage of emerging topics including twin epigenetics as well as epigenetics of gastrointestinal disease, muscle disorders, endocrine disorders, ocular medicine, pediatric diseases, sports medicine, noncoding RNA therapeutics, pain management and regenerative medicine Encompasses a disease-oriented perspective of medical epigenetics as well as diagnostic and prognostic epigenetic approaches to applied medicine

Medical Physiology, 2e Updated Edition E-Book

Medical Physiology, 2e Updated Edition E-Book
with STUDENT CONSULT Online Access

by Walter F. Boron,Emile L. Boulpaep

  • Publisher : Elsevier Health Sciences
  • Release : 2012-01-13
  • Pages : 1350
  • ISBN : 1455711810
  • Language : En, Es, Fr & De
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Medical Physiology, in its updated 2nd edition, firmly relates molecular and cellular biology to the study of human physiology and disease. Drs. Walter Boron and Emile Boulpaep and a team of leading physiologists present you with practical, accurate coverage, continually emphasizing the clinical implications of the material. Each chapter explains the principles and organization of each body system, while more than 1400 high-quality, full-color line drawings and prominently featured clinical examples clarify every concept. This exceptionally detailed and comprehensive guide to physiology is ideal for a rich, straightforward, state-of-the-art understanding of this essential subject. Quickly review important content using prominent boxes included throughout the text to provide clinical examples of disordered physiology. Master difficult concepts with the use of 800 color drawings that feature balloon captions explaining key processes. Find information easily with the intuitive organization by body system and consistent style. Get up-to-date coverage of physiology with updated text and figures. Access the fully searchable text online at www.StudentConsult.com, along with Webnotes, Image Bank, 150 Self-assessment questions, and 10 physiology animations. Stay current thanks to updated material, including a new chapter on Physiology of Aging and a new section on hemostasis. Gain a clear visual understanding with a revised and updated art program of high-quality, full color line drawings and prominently featured clinical examples.

Epigenetics

Epigenetics
A Book

by C. David Allis

  • Publisher : CSHL Press
  • Release : 2007-01
  • Pages : 502
  • ISBN : 0879697245
  • Language : En, Es, Fr & De
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The regulation of gene expression in many biological processes involves epigenetic mechanisms. In this new volume, 24 chapters written by experts in the field discuss epigenetic effects from many perspectives. There are chapters on the basic molecular mechanisms underpinning epigenetic regulation, discussion of cellular processes that rely on this kind of regulation, and surveys of organisms in which it has been most studied. Thus, there are chapters on histone and DNA methylation, siRNAs and gene silencing; X-chromosome inactivation, dosage compensation and imprinting; and discussion of epigenetics in microbes, plants, insects, and mammals. The last part of the book looks at how epigenetic mechanisms act in cell division and differentiation, and how errors in these pathways contribute to cancer and other human diseases. Also discussed are consequences of epigenetics in attempts to clone animals. This book is a major resource for those working in the field, as well as being a suitable text for advanced undergraduate and graduate courses on gene regulation.

Epigenetics in Human Disease

Epigenetics in Human Disease
A Book

by Trygve O. Tollefsbol

  • Publisher : Academic Press
  • Release : 2012
  • Pages : 577
  • ISBN : 0123884152
  • Language : En, Es, Fr & De
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Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike. Comprehensive coverage of fundamental and emergent science and clinical usage Side-by-side coverage of the basis of epigenetic diseases and their treatments Evaluation of recent epigenetic clinical breakthroughs

Epigenetic Biomarker and Personalized Precision Medicine

Epigenetic Biomarker and Personalized Precision Medicine
A Book

by Jiucun Wang,Dongyi He,Momiao Xiong,Yun Liu

  • Publisher : Frontiers Media SA
  • Release : 2020-12-21
  • Pages : 329
  • ISBN : 2889661849
  • Language : En, Es, Fr & De
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Essential 18000 Medical Words Dictionary In English-Sinhala

Essential 18000 Medical Words Dictionary In English-Sinhala

by Nam H Nguyen

  • Publisher : Nam H Nguyen
  • Release : 2018-03-20
  • Pages : 2113
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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a great resource anywhere you go; it is an easy tool that has just the words you want and need! The entire dictionary is an alphabetical list of medical words with definitions. This eBook is an easy-to-understand guide to medical terms for anyone anyways at any time. The content of this eBook is only to be used for informational purposes. ඔබ කොහේ ගියත් විශාල සම්පතක්. එය ඔබට අවශ්ය හා අවශ්ය වචන පමණක් ඇති පහසු මෙවලමක් වේ! සම්පූර්ණ ශබ්දකෝෂය අර්ථ දැක්වීම් සහිත වෛද්ය වචනවල අකාරාදී ලැයිස්තුවකි. මෙම eBook ඕනෑම මොහොතක ඕනෑම මොහොතක ඕනෑම අයෙකු සඳහා වෛද්ය නියමයන් සඳහා පහසුවෙන් තේරුම් ගත හැකි මාර්ගෝපදේශයකි. මෙම eBook අන්තර්ගතය තොරතුරු සඳහා පමණක් භාවිතා කළ යුතුය.

Fundamental Molecular Biology, 2nd Edition

Fundamental Molecular Biology, 2nd Edition
A Book

by Lizabeth A. Allison

  • Publisher : Wiley Global Education
  • Release : 2011-10-03
  • Pages : 672
  • ISBN : 1118209885
  • Language : En, Es, Fr & De
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Perfect for a single term on Molecular Biology and more accessible to beginning students in the field than its encyclopedic counterparts, Fundamental Molecular Biology provides a distillation of the essential concepts of molecular biology, and is supported by current examples, experimental evidence, an outstanding art program, multimedia support and a solid pedagogical framework. The text has been praised both for its balanced and solid coverage of traditional topics, and for its broad coverage of RNA structure and function, epigenetics and medical molecular biology.

The Medical Basis of Psychiatry

The Medical Basis of Psychiatry
A Book

by S. Hossein Fatemi,Paula J. Clayton

  • Publisher : Springer
  • Release : 2016-03-17
  • Pages : 1064
  • ISBN : 1493925288
  • Language : En, Es, Fr & De
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Four years have passed since the last edition (3rd) of this book was published. In the intervening years, several reviews of this book have provided highly encouraging remarks about the value of this book in transmitting information on classification and treatment of psychiatric disorders to the audience. We are proposing to revise all chapters with an eye on accuracy and ease of use, and this is an especially timely endeavor with the upcoming publication of the Diagnostic and Statistical Manual V. All the appropriate new information on biology, etiology, diagnosis and treatment of psychiatric disorders will be added to the current proposed edition. It is our goal to recruit the same authors (if possible) who contributed to the previous edition. While all chapters will be updated (see TOC), those marked by asterisks will be the most likely to undergo more revision. Psychiatry has emerged as a burgeoning scientific field with major advances in etiology and treatment of several disorders. Just as there was excitement in the anatomic advances that took place a hundred years ago when Emil Kraepelin and his collaborators took on the enormous task of classification of psychiatric disorders based on rational scientific thinking, new advances in genetics, biochemistry, neuroanatomy and pharmacotherapy of mental disorders have brought us even closer to a better understanding of complex disorders like schizophrenia, bipolar disorder, depression and even autism. The major goal of the previous edition of this classic book was to update the busy clinician, psychiatric resident and medical student with the most up-to-date information on etiology, diagnosis and treatment of psychiatric disorders. This goal remains the focus of the fourth edition of this book. In this updated and expanded edition, the reader will be provided with the most contemporary information and literature supported by a close survey of the field. This new edition of this classic title, with its focus on biologic and medical aspects of psychiatry, will continue to be of significant help to all interested in the scientific practice of psychiatry.

Growth Disorders 2E

Growth Disorders 2E
A Book

by Chris Kelnar,Martin Savage,Paul Saenger,Chris Cowell

  • Publisher : CRC Press
  • Release : 2007-06-29
  • Pages : 704
  • ISBN : 1444113739
  • Language : En, Es, Fr & De
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Linear growth is a biological process of fundamental importance to the physical and psychological make-up of a child and adolescent but which can be subject to a number of interruptions and disorders. The management and treatment of patients with growth disorders constitues a major, and important, part of practice in clinical paediatrics, while in public health terms growth assessment remains one of the most useful indices of health and economic well being in both developed and the developing world. This book approaches growth and its disorders from both a physiological and pathophysiological standpoint. The book outlines in detail the fundamental biological mechanisms of normal and abnormal linear growth, how to assess growth accurately fundamental to the early detection of abnormality and, importantly, how to manage disorders leading to short and tall stature, and disorders of the timing of puberty. Throughout, emphasis is given on achieving a satisfactory outcome for the child and parent by keeping them fully informed as to what is possible from a particular treatment strategy. The result is a wide-ranging and balanced account of this challenging field drawing on the expertise of a team of international specialists from a variety of backgrounds.

Post-Genomic Cardiology

Post-Genomic Cardiology
A Book

by José Marín-García

  • Publisher : Academic Press
  • Release : 2011-04-28
  • Pages : 688
  • ISBN : 9780080554549
  • Language : En, Es, Fr & De
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Recent advances in molecular and cellular biology have markedly changed our understanding of the heart, and this is having tremendous ramifications for the clinician. This unique reference offers a comprehensive and critical evaluation of this contribution in the field of cardiovascular molecular medicine providing the reader with a sense of new directions in which molecular medicine might be applied. It begins with a detailed primer that makes readily accessible recent molecular, genetic and cellular techniques. Rounding out the coverage of this exciting field are critical and comprenhesive discussions on the use of molecular, genetic and cellular techniques used to identify the etiology and pathophysiology of specific cardiac diseases. * Discusses diagnostic and therapeutic options available not only in the adult and aging individuals but also in infants/children * Numerous illustrations and flow-charts * Explans cutting-edge molecular techniques, including analysis of mitochondria, their role in cardiac dysfunction and updated analysis of Cardioprotection and Metabolic Syndrome * Presentation of recent translational studies for the treatment of cardiovascular diseases is included (e.g., gene therapy, pharmacological treatments and stem cell transplantation)

Animal Biotechnology

Animal Biotechnology
Models in Discovery and Translation

by Ashish S. Verma,Anchal Singh

  • Publisher : Academic Press
  • Release : 2020-06-11
  • Pages : 798
  • ISBN : 0128117257
  • Language : En, Es, Fr & De
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Animal Biotechnology: Models in Discovery and Translation, Second Edition, provides a helpful guide to anyone seeking a thorough review of animal biotechnology and its application to human disease and welfare. This updated edition covers vital fundamentals, including animal cell cultures, genome sequencing analysis, epigenetics and animal models, gene expression, and ethics and safety concerns, along with in-depth examples of implications for human health and prospects for the future. New chapters cover animal biotechnology as applied to various disease types and research areas, including in vitro fertilization, human embryonic stem cell research, biosensors, enteric diseases, biopharming, organ transplantation, tuberculosis, neurodegenerative disorders, and more. Highlights the latest biomedical applications of genetically modified and cloned animals, with a focus on cancer and infectious diseases Offers first-hand accounts of the use of biotechnology tools, including molecular markers, stem cells, animal cultures, tissue engineering, ADME and CAM Assay Includes case studies that illustrate safety assessment issues, ethical considerations, and intellectual property rights associated with the translation of animal biotechnology studies

Stem Cells

Stem Cells
Scientific Facts and Fiction

by Christine Mummery,Anja van de Stolpe,Bernard Roelen,Hans Clevers

  • Publisher : Academic Press
  • Release : 2014-05-23
  • Pages : 448
  • ISBN : 0124115675
  • Language : En, Es, Fr & De
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The second edition of Stem Cells: Scientific Facts and Fiction provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. Building on success of its award-winning preceding edition, the second edition features new chapters on embryonic and iPS cells and stem cells in veterinary science and medicine. It contains major revisions on cancer stem cells to include new culture models, additional interviews with leaders in progenitor cells, engineered eye tissue, and xeno organs from stem cells, as well as new information on "organs on chips" and adult progenitor cells. In the past decades our understanding of stem cell biology has increased tremendously. Many types of stem cells have been discovered in tissues that everyone presumed were unable to regenerate in adults, the heart and the brain in particular. There is vast interest in stem cells from biologists and clinicians who see the potential for regenerative medicine and future treatments for chronic diseases like Parkinson's, diabetes, and spinal cord lesions, based on the use of stem cells; and from entrepreneurs in biotechnology who expect new commercial applications ranging from drug discovery to transplantation therapies. Explains in straightforward, non-specialist language the basic biology of stem cells and their applications in modern medicine and future therapy Includes extensive coverage of adult and embryonic stem cells both historically and in contemporary practice Richly illustrated to assist in understanding how research is done and the current hurdles to clinical practice

Brenner's Encyclopedia of Genetics

Brenner's Encyclopedia of Genetics
A - Ch

by Stanley R. Maloy,Kelly Thomas Hughes

  • Publisher : Unknown Publisher
  • Release : 2013
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The Molecular Biology of Cancer

The Molecular Biology of Cancer
A Book

by Stella Pelengaris,Michael Khan

  • Publisher : John Wiley & Sons
  • Release : 2009-03-12
  • Pages : 544
  • ISBN : 1444309080
  • Language : En, Es, Fr & De
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This comprehensive text provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. Written by an international panel of researchers, specialists and practitioners in the field, the text discusses all aspects of cancer biology from the causes, development and diagnosis through to the treatment of cancer. Written by an international panel of researchers, specialists and practitioners in the field Covers both traditional areas of study and areas of controversy and emerging importance, highlighting future directions for research Features up-to-date coverage of recent studies and discoveries, as well as a solid grounding in the key concepts in the field Each chapter includes key points, chapter summaries, text boxes, and topical references for added comprehension and review Supported by a dedicated website at www.blackwellpublishing.com/pelengaris An excellent text for upper-level courses in the biology of cancer, for medical students and qualified practitioners preparing for higher exams, and for researchers and teachers in the field

Essential Concepts in Molecular Pathology

Essential Concepts in Molecular Pathology
A Book

by William B. Coleman,Gregory J. Tsongalis

  • Publisher : Academic Press
  • Release : 2010-02-16
  • Pages : 462
  • ISBN : 9780080922188
  • Language : En, Es, Fr & De
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This streamlined "essential" version of the Molecular Pathology (2009) textbook extracts key information, illustrations and photographs from the main textbook in the same number and organization of chapters. It is aimed at teaching students in courses where the full textbook is not needed, but the concepts included are desirable (such as graduate students in allied health programs or undergraduates). It is also aimed at students who are enrolled in courses that primarily use a traditional pathology textbook, but need the complementary concepts of molecular pathology (such as medical students). Further, the textbook will be valuable for pathology residents and other postdoctoral fellows who desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. Offers an essential introduction to molecular genetics and the "molecular" aspects of human disease Teaches from the perspective of "integrative systems biology," which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease In-depth presentation of the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease using histopathology. "Traditional" pathology section provides state-of-the-art information on the major forms of disease, their pathologies, and the molecular mechanisms that drive these diseases. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology: molecular diagnostics, molecular assessment, and personalized medicine Each chapter ends with Key Summary Points and Suggested Readings

Epigenetics and Dermatology

Epigenetics and Dermatology
A Book

by Qianjin Lu,Christopher C. Chang,Bruce C. Richardson

  • Publisher : Academic Press
  • Release : 2015-02-16
  • Pages : 520
  • ISBN : 0128012722
  • Language : En, Es, Fr & De
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Epigenetics and Dermatology explores the role of epigenetics in the pathogenesis of autoimmune-related skin diseases and skin cancer. Leading contributors cover common and uncommon skin conditions in which extensive epigenetic research has been done. They explain how environmental exposures (chemicals, drugs, sunlight, diet, stress, smoking, infection, etc.) in all stages of life (from a fetus in-utero to an elderly person) may result in epigenetic changes that lead to development of some skin diseases in life. They also discuss the possibilities of new and emergent epigenetic treatments which are gradually being adopted in management of various skin diseases. Chapters follow a conventional structure, covering fundamental biology of the disease condition, etiology and pathogenesis, diagnosis, commonly available treatments, and epigenetic therapy where applicable. Discusses the basic biology of skin diseases and skin cancers induced or aggravated by aberrant epigenetic changes Evaluates how to approach autoimmune-related skin diseases from a therapeutic perspective using the wealth of emergent epigenetic clinical trials Offers a coherent and structured table of contents with basic epigenetic biology followed by discussion of the spectrum of rheumatologic through neoplastic skin diseases, finally ending with a discourse on epigenetic therapy

Oxford Textbook of Cancer Biology

Oxford Textbook of Cancer Biology
A Book

by Francesco Pezzella,Mahvash Tavassoli,David Kerr

  • Publisher : Oxford University Press
  • Release : 2019-05-02
  • Pages : 496
  • ISBN : 0198779453
  • Language : En, Es, Fr & De
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The study of the biology of tumours has grown to become markedly interdisciplinary, involving chemists, statisticians, epidemiologists, mathematicians, bioinformaticians, and computer scientists alongside biologists, geneticists, and clinicians. The Oxford Textbook of Cancer Biology brings together the most up-to-date developments from different branches of research into one coherent volume, providing a comprehensive and current account of this rapidly evolving field. Structured in eight sections, the book starts with a review of the development and biology of multi-cellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development. The book then illustrates, as once cells become neoplastic, their signalling network is altered and pathological behaviour follows. It explores the changes that cancer cells can induce in nearby normal tissue, the new relationship established between them and the stroma, and the interaction between the immune system and tumour growth. The authors illustrate the contribution provided by high throughput techniques to map cancer at different levels, from genomic sequencing to cellular metabolic functions, and how information technology, with its vast amounts of data, is integrated with traditional cell biology to provide a global view of the disease. The effect of the different types of treatments on the biology of the neoplastic cells are explored to understand on the one side, why some treatments succeed, and on the other, how they can affect the biology of resistant and recurrent disease. The book concludes by summarizing what we know to date about cancer, and in what direction our understanding of cancer is moving. Edited by leading authorities in the field with an international team of contributors, this book is an essential resource for scholars and professionals working in the wide variety of sub-disciplines that make up today's cancer research and treatment community. It is written not only for consultation, but also for easy cover-to-cover reading.

Conservation and the Genetics of Populations

Conservation and the Genetics of Populations
A Book

by Fred W. Allendorf,Gordon Luikart

  • Publisher : John Wiley & Sons
  • Release : 2009-03-12
  • Pages : 664
  • ISBN : 1444309056
  • Language : En, Es, Fr & De
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Conservation and the Genetics of Populations gives acomprehensive overview of the essential background, concepts, andtools needed to understand how genetic information can be used todevelop conservation plans for species threatened withextinction. Provides a thorough understanding of the genetic basis ofbiological problems in conservation. Uses a balance of data and theory, and basic and appliedresearch, with examples taken from both the animal and plantkingdoms. An associated website contains example data sets and softwareprograms to illustrate population genetic processes and methods ofdata analysis. Discussion questions and problems are included at the end ofeach chapter to aid understanding. Features Guest Boxes written by leading people in the fieldincluding James F. Crow, Nancy FitzSimmons, Robert C. Lacy, MichaelW. Nachman, Michael E. Soule, Andrea Taylor, Loren H. Rieseberg,R.C. Vrijenhoek, Lisette Waits, Robin S. Waples and AndrewYoung. Supplementary information designed to support Conservationand the Genetics of Populations including: Downloadable sample chapter Answers to questions and problems Data sets illustrating problems from the book Data analysis software programs Website links An Instructor manual CD-ROM for this title is available. Pleasecontact our Higher Education team at ahref="mailto:[email protected]"[email protected]/afor more information.

Dynamics of Human Biocultural Diversity

Dynamics of Human Biocultural Diversity
A Unified Approach

by Elisa J. Sobo

  • Publisher : Routledge
  • Release : 2019-09-01
  • Pages : 288
  • ISBN : 0429957947
  • Language : En, Es, Fr & De
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This lively text by leading medical anthropologist Elisa Sobo offers a unique, holistic approach to human diversity and rises to the challenge of truly integrating biology and culture. The inviting writing style and fascinating examples make important ideas from complexity theory and epigenetics accessible to students. In this second edition the material has been updated to reflect changes in both the scientific and socio-cultural landscape, for example in relation to topics such as the microbiome and transgender. Readers learn to conceptualize human biology and culture concurrently—as an adaptive biocultural capacity that has helped to produce the rich range of human diversity seen today. With clearly structured topics, an extensive glossary and suggestions for further reading, this text makes a complex, interdisciplinary topic a joy to teach

Molecular Biology

Molecular Biology
A Book

by David P. Clark,Nanette J. Pazdernik

  • Publisher : Elsevier
  • Release : 2013
  • Pages : 907
  • ISBN : 0123785944
  • Language : En, Es, Fr & De
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The last quarter of the 20th century saw major scientific revolutions in genetics and computer technology. This book reflects this massive surge in our understanding of the molecular foundations of genetics. In order to understand where these technological advances are heading, there needs to be a basic understanding of how living organisms function at a molecular level. Molecular Biology, 2e, effectively introduces basic concepts followed by more specific applications as the text evolves. With the addition of Cell Press articles, the content is tied to current topics in the scientific community. NEW: "Focus On Relevant Research" sections integrate primary literature from Cell Press and focus on helping the student learn how to read and understand research to prepare them for the scientific world. NEW: Academic Cell Study Guide features all articles from the text with concurrent case studies to help students build foundations in the content while allowing them to make the appropriate connections to the text. NEW: Animations provided include topics in protein purification, transcription, splicing reactions, cell division and DNA replication and SDS-PAGE Updated chapters on Genomics and Systems Biology, Proteomics, Bacterial Genetics and Molecular Evolution and RNA Updated ancillary package includes flashcards, online self quizzing, references with links to outside content and PowerPoint slides with images. Fully revised art program