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Medical Modelling

Medical Modelling
The Application of Advanced Design and Rapid Prototyping Techniques in Medicine

by Richard Bibb,Dominic Eggbeer,Abby Paterson

  • Publisher : Woodhead Publishing
  • Release : 2014-12-13
  • Pages : 516
  • ISBN : 1782423133
  • Language : En, Es, Fr & De
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Medical modelling and the principles of medical imaging, Computer Aided Design (CAD) and Rapid Prototyping (also known as Additive Manufacturing and 3D Printing) are important techniques relating to various disciplines - from biomaterials engineering to surgery. Building on the success of the first edition, Medical Modelling: The application of Advanced Design and Rapid Prototyping techniques in medicine provides readers with a revised edition of the original text, along with key information on innovative imaging techniques, Rapid Prototyping technologies and case studies. Following an overview of medical imaging for Rapid Prototyping, the book goes on to discuss working with medical scan data and techniques for Rapid Prototyping. In this second edition there is an extensive section of peer-reviewed case studies, describing the practical applications of advanced design technologies in surgical, prosthetic, orthotic, dental and research applications. Covers the steps towards rapid prototyping, from conception (modelling) to manufacture (manufacture) Includes a comprehensive case studies section on the practical application of computer-aided design (CAD) and rapid prototyping (RP) Provides an insight into medical imaging for rapid prototyping and working with medical scan data

Modelling Degradation of Bioresorbable Polymeric Medical Devices

Modelling Degradation of Bioresorbable Polymeric Medical Devices
A Book

by J Pan

  • Publisher : Elsevier
  • Release : 2014-10-24
  • Pages : 260
  • ISBN : 1782420258
  • Language : En, Es, Fr & De
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The use of bioresorbable polymers in stents, fixation devices and tissue engineering is revolutionising medicine. Both industry and academic researchers are interested in using computer modelling to replace some experiments which are costly and time consuming. This book provides readers with a comprehensive review of modelling polymers and polymeric medical devices as an alternative to practical experiments. Chapters in part one provide readers with an overview of the fundamentals of biodegradation. Part two looks at a wide range of degradation theories for bioresorbable polymers and devices. The final set of chapters look at advances in modelling biodegradation of bioresorbable polymers. This book is an essential guide to those concerned with replacing tests and experiments with modelling. Provides a comprehensive mathematical framework for computer modelling of polymers and polymeric medical devices that can significantly reduce the number of experiments needed. Reviews the fundamental methods of modelling degradation, and applies these to particular materials including amorphous bioresorbable polyesters, semicrystalline biodegradable polyesters, and composite materials made of biodegradable polyesters and triclcium phosphates

Modelling in Medicine and Biology VIII

Modelling in Medicine and Biology VIII
A Book

by C. A. Brebbia

  • Publisher : WIT Press
  • Release : 2009
  • Pages : 324
  • ISBN : 1845641833
  • Language : En, Es, Fr & De
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Featuring contributions from the eighth International Conference on Modelling in Medicine and Biology, this volume covers a broad spectrum of topics including the application of computers to simulate biomedical phenomena. It will be of interest to medical and physical scientists and engineers.

Modelling in Medicine and Biology

Modelling in Medicine and Biology
A Book

by C. A. Brebbia

  • Publisher : WIT Press
  • Release : 2011-01-01
  • Pages : 209
  • ISBN : 1845645723
  • Language : En, Es, Fr & De
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The idea of preparing this volume originated from the ever increasing importance of computational modelling of complex problems in medicine. Considerable advances have been made in this area as demonstrated by the continued success of the International Conference on Modelling in Medicine and Biology organised by the Wessex Institute of Technology.The work reported at those meetings and the research carried out at the Wessex Institute of Technology indicated the increasing interaction and collaboration between medical and engineering scientists. Advances presented at these conferences are now being used in practice for a wide range of medical and surgical applications.The considerable improvements and evolution of the field has led to some of the best scientists, who have participated in our conferences, to write an article on their most recent research. This has led to thirteen outstanding articles published in this volume which encompass important areas of biomedical modelling.

Mixture Modelling for Medical and Health Sciences

Mixture Modelling for Medical and Health Sciences
A Book

by Shu-Kay Ng

  • Publisher : CRC Press
  • Release : 2019-05-03
  • Pages : 300
  • ISBN : 148223677X
  • Language : En, Es, Fr & De
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Mixture Modelling for Medical and Health Sciences provides a direct connection between theoretical developments in mixture modelling and their applications in real world problems. The book describes the development of the most important concepts through comprehensive analyses of real and practical examples taken from real-life research problems in

Modelling Survival Data in Medical Research, Second Edition

Modelling Survival Data in Medical Research, Second Edition
A Book

by David Collett

  • Publisher : CRC Press
  • Release : 2003-03-28
  • Pages : 410
  • ISBN : 1584883251
  • Language : En, Es, Fr & De
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Critically acclaimed and resoundingly popular in its first edition, Modelling Survival Data in Medical Research has been thoroughly revised and updated to reflect the many developments and advances--particularly in software--made in the field over the last 10 years. Now, more than ever, it provides an outstanding text for upper-level and graduate courses in survival analysis, biostatistics, and time-to-event analysis.The treatment begins with an introduction to survival analysis and a description of four studies that lead to survival data. Subsequent chapters then use those data sets and others to illustrate the various analytical techniques applicable to such data, including the Cox regression model, the Weibull proportional hazards model, and others. This edition features a more detailed treatment of topics such as parametric models, accelerated failure time models, and analysis of interval-censored data. The author also focuses the software section on the use of SAS, summarising the methods used by the software to generate its output and examining that output in detail. Profusely illustrated with examples and written in the author's trademark, easy-to-follow style, Modelling Survival Data in Medical Research, Second Edition is a thorough, practical guide to survival analysis that reflects current statistical practices.

Modelling Survival Data in Medical Research

Modelling Survival Data in Medical Research
A Book

by David Collett

  • Publisher : CRC Press
  • Release : 2015-05-04
  • Pages : 548
  • ISBN : 1498731694
  • Language : En, Es, Fr & De
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Modelling Survival Data in Medical Research describes the modelling approach to the analysis of survival data using a wide range of examples from biomedical research.Well known for its nontechnical style, this third edition contains new chapters on frailty models and their applications, competing risks, non-proportional hazards, and dependent censo

Strategic Modelling and Business Dynamics

Strategic Modelling and Business Dynamics
A Feedback Systems Approach

by John Morecroft

  • Publisher : John Wiley & Sons
  • Release : 2007-09-10
  • Pages : 464
  • ISBN : 0470012862
  • Language : En, Es, Fr & De
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John Morecroft's book is an ideal text for students interested in system modelling and its application to a range of real world problems. The book covers all that is necessary to develop expertise in system dynamics modelling and through the range of applications makes a persuasive case for the power and scope of the approach. As such it will appeal to practitioners as well as students. Robert Dyson, Professor of Operational Research, Associate Dean, Warwick Business School. Much more than an introduction, John Morecroft's Strategic Modelling and Business Dynamics uses interactive "management flight simulators" to create an engaging and effective learning environment in which readers, whatever their background, can develop their intuition about complex dynamic systems. The numerous examples provide a rich test-bed for the development of systems thinking and modelling skills John Sterman, Jay W. Forrester Professor of Management, MIT Sloan School of Management This book, with its vivid examples and simulators, will help to bring modelling, system dynamics and simulation into the mainstream of management education where they now belong. John A. Quelch, Professor of Marketing, Harvard Business School, Former Dean of London Business School This text fills the gap between texts focusing on the purely descriptive systems approach and the more technical system dynamics ones. Ann van Ackere, Professor of Decision Sciences, HEC Lausanne, Universit? de Lausanne Strategic modelling based on system dynamics is a powerful tool for understanding how firms adapt to a changing environment. The author demonstrates the appeal and power of business modelling to make sense of strategic initiatives and to anticipate their impacts through simulation. The book offers various simulators that allow readers to conduct their own policy experiments. Dr. Erich Zahn, Professor of Strategic Management, Betriebswirtschaftliches Institut, University of Stuttgart A website to accompany the book can be found at www.wiley.com/college/morecroft housing supplementary material for both students and lecturers.

Decision Modelling for Health Economic Evaluation

Decision Modelling for Health Economic Evaluation
A Book

by Andrew H. Briggs,Karl Claxton,Mark J. Sculpher

  • Publisher : Oxford University Press, USA
  • Release : 2006
  • Pages : 237
  • ISBN : 0198526628
  • Language : En, Es, Fr & De
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This is a practical guide to the use of modelling techniques, starting with the basics of constructing different forms of model, the population of the model with input parameter estimates, analysis of the results, and progression to the holistic view of models as a tool to inform future research exercises. Key techniques and approaches are discussed, and a comprehensive set of example exercises take the reader through how to conduct decision-analytic modelling. These exercises are supported with templates and solutions made available via the book website. -- BOOK JACKET.

Advanced Manufacturing Technology for Medical Applications

Advanced Manufacturing Technology for Medical Applications
Reverse Engineering, Software Conversion and Rapid Prototyping

by Ian Gibson

  • Publisher : John Wiley & Sons
  • Release : 2006-06-14
  • Pages : 254
  • ISBN : 0470032847
  • Language : En, Es, Fr & De
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Advanced manufacturing technologies (AMTs) combine novel manufacturing techniques and machines with the application of information technology, microelectronics and new organizational practices within the manufacturing sector. They include "hard" technologies such as rapid prototyping, and "soft" technologies such as scanned point cloud data manipulation. AMTs contribute significantly to medical and biomedical engineering. The number of applications is rapidly increasing, with many important new products now under development. Advanced Manufacturing Technology for Medical Applications outlines the state of the art in advanced manufacturing technology and points to the future development of this exciting field. Early chapters look at actual medical applications already employing AMT, and progress to how reverse engineering allows users to create system solutions to medical problems. The authors also investigate how hard and soft systems are used to create these solutions ready for building. Applications follow where models are created using a variety of different techniques to suit different medical problems One of the first texts to be dedicated to the use of rapid prototyping, reverse engineering and associated software for medical applications Ties together the two distinct disciplines of engineering and medicine Features contributions from experts who are recognised pioneers in the use of these technologies for medical applications Includes work carried out in both a research and a commercial capacity, with representatives from 3 companies that are established as world leaders in the field – Medical Modelling, Materialise, & Anatomics Covers a comprehensive range of medical applications, from dentistry and surgery to neurosurgery and prosthetic design Medical practitioners interested in implementing new advanced methods will find Advanced Manufacturing Technology for Medical Applications invaluable as will engineers developing applications for the medical industry. Academics and researchers also now have a vital resource at their disposal.

Modelling in Medicine and Biology VI

Modelling in Medicine and Biology VI
A Book

by Mauro Ursino

  • Publisher : WIT Press
  • Release : 2005
  • Pages : 601
  • ISBN : 1845640241
  • Language : En, Es, Fr & De
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Featuring contributions from the Sixth International Conference on Modelling in Medicine and Biology, this volume covers a broad spectrum of topics including the application of computers to simulate biomedical phenomena. It will be of interest both to medical and physical scientists and engineers and to professionals working in medical enterprises actively involved in this field.Areas highlighted include: Simulation of Physiological Processes; Computational Fluid Dynamics in Biomedicine; Orthopaedics and Bone Mechanics; Simulations in Surgery; Design and Simulation of Artificial Organs; Computers and Expert Systems in Medicine; Advanced Technology in Dentistry; Gait and Motion Analysis; Cardiovascular System; Virtual Reality in Medicine; Biomechanics; and Neural Systems.

Modelling in Medicine and Biology VII

Modelling in Medicine and Biology VII
A Book

by C. A. Brebbia

  • Publisher : WIT Press
  • Release : 2007
  • Pages : 332
  • ISBN : 1845640896
  • Language : En, Es, Fr & De
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Projections for advances in medical and biological technology will transform medical care and treatment. This is in great part due to the results of interaction and collaborations between the medical sciences and engineering. These advances will result in substantial progressions in health care and in the quality of life of the population.Computer models in particular have been increasingly successful in simulating biological phenomena. These are lending support to many applications, including amongst others cardiovascular systems, the study of orthopaedics and biomechanics, electrical simulation. Another important contribution, due to the wide availability of computational facilities and the development of better numerical algorithms, is the ability to acquire analyses, manage and visualise massive amounts of data. Containing papers presented at the Seventh International Conference on Modelling in Medicine and Biology, this book covers a broad range of topics which will be of particular interest to medical and physical scientists and engineers interested in the latest developments in simulations in medicine. It will also be relevant to professionals working in medical enterprises which are actively involved in this field. Topics include: Cardiovascular Systems; Simulations in Surgery; Biomechanics; Advanced Technology in Dentistry; Simulation of Physiological Processes; Neural Systems; Computational Fluid Dynamics in Biomedicine; Orthopaedics and Bone Mechanics; Data Acquisition and Analysis; Virtual Reality in Medicine; Expert Systems in Medicine; Design and Simulation of Artificial Organs.

Multilevel Modelling for Public Health and Health Services Research

Multilevel Modelling for Public Health and Health Services Research
Health in Context

by Alastair H. Leyland,Peter P. Groenewegen

  • Publisher : Springer Nature
  • Release : 2020-01-01
  • Pages : 288
  • ISBN : 3030348016
  • Language : En, Es, Fr & De
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This open access book is a practical introduction to multilevel modelling or multilevel analysis (MLA) - a statistical technique being increasingly used in public health and health services research. The authors begin with a compelling argument for the importance of researchers in these fields having an understanding of MLA to be able to judge not only the growing body of research that uses it, but also to recognise the limitations of research that did not use it. The volume also guides the analysis of real-life data sets by introducing and discussing the use of the multilevel modelling software MLwiN, the statistical package that is used with the example data sets. Importantly, the book also makes the training material accessible for download - not only the datasets analysed within the book, but also a freeware version of MLwiN to allow readers to work with these datasets. The book's practical review of MLA comprises: Theoretical, conceptual, and methodological background Statistical background The modelling process and presentation of research Tutorials with example datasets Multilevel Modelling for Public Health and Health Services Research: Health in Context is a practical and timely resource for public health and health services researchers, statisticians interested in the relationships between contexts and behaviour, graduate students across these disciplines, and anyone interested in utilising multilevel modelling or multilevel analysis. "Leyland and Groenewegen's wealth of teaching experience makes this book and its accompanying tutorials especially useful for a practical introduction to multilevel analysis." ̶ Juan Merlo, Professor of Social Epidemiology, Lund University "Comprehensive and insightful. A must for anyone interested in the applications of multilevel modelling to population health". ̶ S. (Subu) V. Subramanian, Professor of Population Health and Geography, Harvard University.

Information Modelling and Knowledge Bases VI

Information Modelling and Knowledge Bases VI
A Book

by Hannu Kangassalo,Setsuo Ohsuga

  • Publisher : IOS Press
  • Release : 1995
  • Pages : 507
  • ISBN : 9789051992120
  • Language : En, Es, Fr & De
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This sixth IMKB volume attempts to synthesize research done over a longer period of time in a reference book format. The work presents in survey articles the efforts to study foundations and applications of conceptual modelling in various environments. The motivation of these efforts is the fact that conceptual modelling and knowledge representation together with various kinds of inference systems are important subfields in the design and use of information systems. The modelling problem is essential in many disciplines, such as database design, knowledge engineering, logic, artificial intelligence, cognitive science, philosophy, linguistics, etc. A central and comprehensive bibliography is included.

Mathematical Modelling and Optimization of Engineering Problems

Mathematical Modelling and Optimization of Engineering Problems
A Book

by J. A. Tenreiro Machado,Necati Özdemir,Dumitru Baleanu

  • Publisher : Springer Nature
  • Release : 2020-02-12
  • Pages : 202
  • ISBN : 3030370623
  • Language : En, Es, Fr & De
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This book presents recent developments in modelling and optimization of engineering systems and the use of advanced mathematical methods for solving complex real-world problems. It provides recent theoretical developments and new techniques based on control, optimization theory, mathematical modeling and fractional calculus that can be used to model and understand complex behavior in natural phenomena including latest technologies such as additive manufacturing. Specific topics covered in detail include combinatorial optimization, flow and heat transfer, mathematical modelling, energy storage and management policy, artificial intelligence, optimal control, modelling and optimization of manufacturing systems.

Modelling Methodology for Physiology and Medicine

Modelling Methodology for Physiology and Medicine
A Book

by Ewart Carson,Claudio Cobelli

  • Publisher : Newnes
  • Release : 2013-12-05
  • Pages : 588
  • ISBN : 0124095259
  • Language : En, Es, Fr & De
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Modelling Methodology for Physiology and Medicine, Second Edition, offers a unique approach and an unprecedented range of coverage of the state-of-the-art, advanced modeling methodology that is widely applicable to physiology and medicine. The second edition, which is completely updated and expanded, opens with a clear and integrated treatment of advanced methodology for developing mathematical models of physiology and medical systems. Readers are then shown how to apply this methodology beneficially to real-world problems in physiology and medicine, such as circulation and respiration. The focus of Modelling Methodology for Physiology and Medicine, Second Edition, is the methodology that underpins good modeling practice. It builds upon the idea of an integrated methodology for the development and testing of mathematical models. It covers many specific areas of methodology in which important advances have taken place over recent years and illustrates the application of good methodological practice in key areas of physiology and medicine. It builds on work that the editors have carried out over the past 30 years, working in cooperation with leading practitioners in the field. Builds upon and enhances the reader's existing knowledge of modeling methodology and practice Editors are internationally renowned leaders in their respective fields Provides an understanding of modeling methodologies that can address real problems in physiology and medicine and achieve results that are beneficial either in advancing research or in providing solutions to clinical problems

The Role of Model Integration in Complex Systems Modelling

The Role of Model Integration in Complex Systems Modelling
An Example from Cancer Biology

by Manish I. Patel,Sylvia Nagl

  • Publisher : Springer Science & Business Media
  • Release : 2010-09-08
  • Pages : 168
  • ISBN : 3642156029
  • Language : En, Es, Fr & De
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Model integration – the process by which different modelling efforts can be brought together to simulate the target system – is a core technology in the field of Systems Biology. In the work presented here model integration was addressed directly taking cancer systems as an example. An in-depth literature review was carried out to survey the model forms and types currently being utilised. This was used to formalise the main challenges that model integration poses, namely that of paradigm (the formalism on which a model is based), focus (the real-world system the model represents) and scale. A two-tier model integration strategy, including a knowledge-driven approach to address model semantics, was developed to tackle these challenges. In the first step a novel description of models at the level of behaviour, rather than the precise mathematical or computational basis of the model, is developed by distilling a set of abstract classes and properties. These can accurately describe model behaviour and hence describe focus in a way that can be integrated with behavioural descriptions of other models. In the second step this behaviour is decomposed into an agent-based system by translating the models into local interaction rules. The book provides a detailed and highly integrated presentation of the method, encompassing both its novel theoretical and practical aspects, which will enable the reader to practically apply it to their model integration needs in academic research and professional settings. The text is self-supporting. It also includes an in-depth current bibliography to relevant research papers and literature. The review of the current state of the art in tumour modelling provides added value.

Modelling Survival Data in Medical Research, Third Edition

Modelling Survival Data in Medical Research, Third Edition
A Book

by David Collett

  • Publisher : Chapman and Hall/CRC
  • Release : 2014-12-11
  • Pages : 548
  • ISBN : 9781439856789
  • Language : En, Es, Fr & De
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Modelling Survival Data in Medical Research describes the modelling approach to the analysis of survival data using a wide range of examples from biomedical research. Well known for its nontechnical style, this third edition contains new chapters on frailty models and their applications, competing risks, non-proportional hazards, and dependent censoring. It also describes techniques for modelling the occurrence of multiple events and event history analysis. Earlier chapters are now expanded to include new material on a number of topics, including measures of predictive ability and flexible parametric models. Many new data sets and examples are included to illustrate how these techniques are used in modelling survival data. Bibliographic notes and suggestions for further reading are provided at the end of each chapter. Additional data sets to obtain a fuller appreciation of the methodology, or to be used as student exercises, are provided in the appendix. All data sets used in this book are also available in electronic format online. This book is an invaluable resource for statisticians in the pharmaceutical industry, professionals in medical research institutes, scientists and clinicians who are analyzing their own data, and students taking undergraduate or postgraduate courses in survival analysis.

Mathematical Modelling in Biomedicine

Mathematical Modelling in Biomedicine
Optimal Control of Biomedical Systems

by Y. Cherruault

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 258
  • ISBN : 9400954921
  • Language : En, Es, Fr & De
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Approach your problems from the right It isn't that they can't see the solution. It end and begin with the answers. Then is that they can't see the problem. one day, perhaps you will find the final question. G.K. Chesterton. The Scandal of Father Brown 'The point of a Pin'. 'The Hermit Clad in Crane Feathers' in R. van Gulik's The Chinese Maze Murders. Growing specialization and diversification have brought a host of monographs and textbooks on increasingly specialized topics. However, the "tree" of knowledge of mathematics and related fields does not grow only by putting forth new branches. It also happens, quite often in fact, that branches which were thought to be completely disparate are suddenly seen to be related. Further, the kind and level of sophistication of mathematics applied in various sciences has changed drastically in recent years: measure theory is used (non-trivially) in regional and theoretical economics; algebraic geometry interacts with physics; the Minkowsky lemma, cod ing theory and the structure of water meet one another in packing and covering theory; quantum fields, crystal defects and mathematical pro gramming profit from homotopy theory; Lie algebras are relevant to filtering; and prediction and electrical engineering can use Stein spaces.

Computational Modelling of Objects Represented in Images. Fundamentals, Methods and Applications

Computational Modelling of Objects Represented in Images. Fundamentals, Methods and Applications
Proceedings of the International Symposium CompIMAGE 2006 (Coimbra, Portugal, 20-21 October 2006)

by João Manuel R.S. Tavares,Jorge R.M. Natal

  • Publisher : CRC Press
  • Release : 2018-05-08
  • Pages : 480
  • ISBN : 1351377124
  • Language : En, Es, Fr & De
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This book contains keynote lectures and full papers presented at the International Symposium on Computational Modelling of Objects Represented in Images (CompIMAGE), held in Coimbra, Portugal, on 20-21 October 2006. International contributions from nineteen countries provide a comprehensive coverage of the current state-of-the-art in the fields of: - Image Processing and Analysis; - Image Segmentation; - Data Interpolation; - Registration, Acquisition and Compression; - 3D Reconstruction; - Objects Tracking; - Motion and Deformation Analysis; - Objects Simulation; - Medical Imaging; - Computational Bioimaging and Visualization. Related techniques also covered in this book include the finite element method, modal analyses, stochastic methods, principal and independent components analyses and distribution models. Computational Modelling of Objects Represented in Images will be useful to academics, researchers and professionals in Computational Vision (image processing and analysis), Computer Sciences, and Computational Mechanics.