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Mesenchymal Stem Cells in Human Health and Diseases

Mesenchymal Stem Cells in Human Health and Diseases
A Book

by Ahmed H.K. El-Hashash

  • Publisher : Academic Press
  • Release : 2020-01-07
  • Pages : 228
  • ISBN : 0128205334
  • Language : En, Es, Fr & De
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Mesenchymal Stem Cells in Human Health and Diseases provides a contemporary overview of the fast-moving field of MSC biology, regenerative medicine and therapeutics. MSCs offer the potential to dramatically reduce human suffering from disease. Numerous MSC-based studies are ongoing each year, each offering hope for novel treatments in human disease. This book provides information on MSC application in well-studied human diseases and tissue repair/regeneration and recent advances in their research and treatment. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in our understanding of MSC biology. Includes insights ranging from MSC biology and development through the derivation and identification and properties of MSCs Helps to identify potential innovative solutions for restoring normal morphogenesis and/or regeneration of diseased organs Discusses the fact-based promise of MSC therapeutics and regenerative medicine in the real world

Developmental and Stem Cell Biology in Health and Disease

Developmental and Stem Cell Biology in Health and Disease
A Book

by Ahmed El-Hashash

  • Publisher : Bentham Science Publishers
  • Release : 2016-07-14
  • Pages : 260
  • ISBN : 1681082195
  • Language : En, Es, Fr & De
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Research into stem cells started in the 1960s with experiments on spleen cultures. Evans and Kaufman made a breakthrough in mouse embryo culturing and embryonic stem cell extraction in 1981, followed by the work of Thomson in 1998 on the technique for extracting human embryonic stem cells. Since then, stem cell research has rapidly expanded as a therapeutic avenue for different diseases in humans. This book explains the basic developmental biology of stem cells including the development of stem cells during the implantation stage in utero to the regulation of stem cell division. Medical applications of stem cells in the therapy of diseases such as cancer, neurodegenerative diseases, and bone diseases are also explained in subsequent chapters. The book also explains the effect of parasitic cells on stem cell growth. Concepts in the book are explained in a simple clear manner, making this book an informative reference for non-experts, students and professionals in the field of biology and medicine.

Lung Stem Cells in Development, Health and Disease

Lung Stem Cells in Development, Health and Disease
A Book

by Nikolic, Marko Z.,Hogan, Brigid L.M.

  • Publisher : European Respiratory Society
  • Release : 2021-04-01
  • Pages : 392
  • ISBN : 1849841349
  • Language : En, Es, Fr & De
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Most organs in the adult human body are able to maintain themselves and undergo repair after injury; these processes are largely dependent on stem cells. In this Monograph, the Guest Editors bring together leading authors in the field to provide information about the different classes of stem cells present both in the developing and adult lung: where they are found, how they function in homeostasis and pathologic conditions, the mechanisms that regulate their behaviour, and how they may be harnessed for therapeutic purposes. The book focuses on stem cells in the mouse and human lung but also includes the ferret as an increasingly important new model organism. Chapters also discuss how lung tissue, including endogenous stem cells, can be generated in vitro from pluripotent stem cell lines. This state-of-the-art collection comprehensively covers one of the most exciting areas of respiratory science

Women's Health and Disease, Volume 1205

Women's Health and Disease, Volume 1205
A Book

by George Creatsas,George Mastorakos

  • Publisher : Wiley-Blackwell
  • Release : 2010-10-25
  • Pages : 292
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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"This volume presents manuscripts stemming from the "The 7th Athens Congress on Women's Health and Disease: Gynecologic, Endocrine, and Reproductive Issues" held on September 11-13, 2008 in Athens, Greece"--Caption.

Effect of Cyclic AMP in Modulating Cell Differentiation and Survival Behaviors

Effect of Cyclic AMP in Modulating Cell Differentiation and Survival Behaviors
A Book

by Linxia Zhang

  • Publisher : Unknown Publisher
  • Release : 2010
  • Pages : 346
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Mesenchymal Stem Cell Therapy

Mesenchymal Stem Cell Therapy
A Book

by Lucas G. Chase,Mohan C Vemuri

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-12
  • Pages : 456
  • ISBN : 1627032002
  • Language : En, Es, Fr & De
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Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

Molecular Biology of the Cell

Molecular Biology of the Cell
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2007
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Autophagy in Health and Disease

Autophagy in Health and Disease
Potential Therapeutic Approaches

by Kursad Turksen

  • Publisher : Springer
  • Release : 2018-10-06
  • Pages : 177
  • ISBN : 3319981463
  • Language : En, Es, Fr & De
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This timely volume explores the impact of autophagy in various human diseases, emphasizing the cell biological aspects and focusing on therapeutic approaches to these diseases. The chapters cover autophagy and its potential applications on diseases ranging from obesity, osteoarthritis, pulmonary fibrosis, and inflammation, through ALS, Parkinson's, retinal degeneration, breast cancer, alcoholic liver disease and more. The final chapters round out the book with a discussion of autophagy in drug discovery and 'bench to bedside'. Chapters are contributed by leading authorities and describe the general concepts of autophagy in health and disease, marrying cell biology and pharmacology and covering: studies derived from preclinical experiments, manufacturing considerations,and regulatory requirements pertaining to drug discovery and manufacturing and production. This volume will be useful for basic scientists as well as already practicing clinicians and advanced graduate students.

Thymosins in Health and Disease

Thymosins in Health and Disease
Second International Symposium, Volume 1194

by Allan L. Goldstein,Enrico Garaci

  • Publisher : Wiley-Blackwell
  • Release : 2010-06
  • Pages : 230
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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"This volume presents manuscripts stemming from the "Second International Symposium on Thymosins in Health and Disease," held on September 30 to October 2, 2009 in Catania, Italy."--P. v.

Nature

Nature
A Book

by Sir Norman Lockyer

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Tissue Engineering of Chondrocyte and Mesenchymal Stem Cell Seeded Alginates

Tissue Engineering of Chondrocyte and Mesenchymal Stem Cell Seeded Alginates
A Mechanical and Biocemical Analysis

by Megan Dines

  • Publisher : Unknown Publisher
  • Release : 2004
  • Pages : 108
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Handbook of Growth and Growth Monitoring in Health and Disease

Handbook of Growth and Growth Monitoring in Health and Disease
A Book

by Victor R. Preedy

  • Publisher : Springer Science & Business Media
  • Release : 2011-12-02
  • Pages : 3164
  • ISBN : 1441917942
  • Language : En, Es, Fr & De
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Growth is one of the human body’s most intricate processes: each body part or region has its own unique growth patterns. Yet at the individual and population levels, growth patterns are sensitive to adverse conditions, genetic predispositions, and environmental changes. And despite the body’s capacity to compensate for these developmental setbacks, the effects may be far-reaching, even life-long. The Handbook of Growth and Growth Monitoring in Health and Disease brings this significant and complex field together in one comprehensive volume: impact of adverse variables on growth patterns; issues at different stages of prenatal development, childhood, and adolescence; aspects of catch-up growth, endocrine regulation, and sexual maturation; screening and assessment methods; and international perspectives. Tables and diagrams, applications to other areas of health and disease, and summary points help make the information easier to retain. Together, these 140 self-contained chapters in 15 sections [ok?] cover every area of human growth, including: Intrauterine growth retardation. Postnatal growth in normal and abnormal situations. Cells and growth of tissues. Sensory growth and development. Effects of disease on growth. Methods and standards for assessment of growth, and more. The Handbook of Growth and Growth Monitoring in Health and Disease is an invaluable addition to the reference libraries of a wide range of health professionals, among them health scientists, physicians, physiologists, nutritionists, dieticians, nurses, public health researchers, epidemiologists, exercise physiologists, and physical therapists. It is also useful to college-level students and faculty in the health disciplines, and to policymakers and health economists.

Lung Stem Cells in the Epithelium and Vasculature

Lung Stem Cells in the Epithelium and Vasculature
A Book

by Amy Firth,Jason X.-J. Yuan

  • Publisher : Springer
  • Release : 2015-05-23
  • Pages : 345
  • ISBN : 3319162322
  • Language : En, Es, Fr & De
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This book covers the identification and role of endogenous lung stem cells in health and disease, particularly the most recent advances. In addition, it discusses the rapidly growing field of stem cells and cell therapy as it relates to lung biology and disease as well as ex vivo lung bioengineering. Such approaches may provide novel therapeutic approaches for lung diseases. Human pluripotent stem cell differentiation to model the pulmonary epithelium and vasculature is also discussed. World-recognized scientists who specialize in studying both the lung epithelium and pulmonary vasculature contribute the chapters. Topics covered include: stem cell niches in the lung, the role of progenitor cells in fibrosis and asthma, iPSC in modeling lung disease, vascular repair by endothelial progenitor cells and circulating fibrocytes in pulmonary vascular remodeling. This volume of the Stem Cell Biology and Regenerative Medicine series is essential reading for researchers and clinicians interested in stem cells, lung biology and regenerative medicine. It is also an invaluable resource for advanced students studying cell biology, regenerative medicine and lung physiology.

Radiation Risk Perspectives

Radiation Risk Perspectives
Proceedings of the Second Nagasaki Symposium of International Consortium for Medical Care of Hibakusha and Radiation Life Science, Nagasaki, Japan, 26-27 July 2006

by International Consortium for Medical Care of Hibakusha and Radiation Life Science. Nagasaki Symposium

  • Publisher : Elsevier Science Health Science Division
  • Release : 2007
  • Pages : 298
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The purpose of the symposium of which this is the proceedings volume, was to discuss the issue of radiation damage to tissues and alert those in positions of authority on how to cope with radiation risk analysis and low dosage dangers.

Microfluidic Technologies for Human Health

Microfluidic Technologies for Human Health
A Book

by Ali Khademhosseini,Utkan Demirci,Robert Langer

  • Publisher : World Scientific
  • Release : 2012
  • Pages : 478
  • ISBN : 9814405515
  • Language : En, Es, Fr & De
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Ch. 1. A microscale bioinspired cochlear-like sensor / Robert D. White, Robert Littrell, and Karl Grosh -- ch. 2. Systematic evaluation of the efficiencies of proteins and chemicals in pharmaceutical applications / Morgan Hamon and Jong Wook Hong -- ch. 3. Microfluidic glucose sensors / Jithesh V. Veetil ... [et al.] -- ch. 4. Applications of microfabrication and microfluidic techniques in mesenchymal stem cell research / Abhijit Majumder ... [et al.] -- ch. 5. Patient-specific modeling of low-density lipoprotein transport in coronary arteries / Ufuk Olgac -- ch. 6. Point-of-care microdevices for global health diagnostics of infectious diseases / Sau Yin Chin ... [et al.] -- ch. 7. Integrated microfluidic sample preparation for chip-based molecular diagnostics / Jane Y. Zhang ... [et al.] -- ch. 8. Microfluidic devices for cellular proteomic studies / Yihong Zhan and Chang Lu -- ch. 9. Microfluidics for neuroscience: novel tools and future implications / Vivian M. Hernandez and P. Hande Ozdinler -- ch. 10. Microfluidics: on-chip platforms as in vitro disease models / Shan Gao, Erkin Seker, and Martin L. Yarmush -- ch. 11. Application of microfluidics in stem cell and tissue engineering / Sasha H. Bakhru, Christopher Highley, and Stefan Zappe -- ch. 12. Microfluidic "on-the-fly" fabrication of microstructures for biomedical applications / Edward Kang, Sau Fung Wong, and Sang-Hoon Lee -- ch. 13. Microfluidics as a promising tool toward distributed viral detection / Elodie Sollier and Dino Di Carlo -- ch. 14. Electrophoresis and dielectrophoresis for lab-on-a-chip (LOC) analyses / Yagmur Demircan, Gurkan Yilmaz, and Haluk Kulah -- ch. 15. Ultrasonic embossing of carbon nanotubes for the fabrication of polymer microfluidic chips for DNA sample purification / Puttachat Khuntontong, Min Gong, and Zhiping Wang -- ch. 16. Ferrofluidics / A. Rezzan Kose and Hur Koser -- ch. 17. Antibody-based blood bioparticle capture and separation using microfluidics for global health / ZhengYuan Luo ... [et al.] -- ch. 18. Applications of quantum dots for fluorescence imaging in biomedical research / ShuQi Wang ... [et al.]

Research EU.

Research EU.
Results magazine

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2011-10
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Stem Cell Biology

Stem Cell Biology
Development and Plasticity

by Jitka Ourednick

  • Publisher : Unknown Publisher
  • Release : 2005
  • Pages : 200
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Stem cells have generated considerable interest recently in the scientific, clinical, and public arenas. It is essential that we gain a broader understanding of the factors that regulate the biology of stem cells: their ability for self-renewal, differentiation and plasticity, as well as the differences between embryonic and adult stem cells. To gain a better understanding of how and whether stem cells can be manipulated to replace cells in diseased tissues will depend on gaining a better understanding of their normal developmental properties. This volume offers contributions from numerous interdisciplinary areas bridging biotechnology and biomedical sciences. The ability to isolate and maintain pluripotent stem cells in culture offers exciting possibilities for replacing damaged or diseased organs and tissues. Moreover, stem cells will provide opportunities for major advances in our understanding of fundamental developmental processes.

Annual Report

Annual Report
A Book

by Institute of Medical and Veterinary Science (S.A.). Council

  • Publisher : Unknown Publisher
  • Release : 2006
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The Japanese Journal of Veterinary Research

The Japanese Journal of Veterinary Research
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2005
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Space Life Sciences

Space Life Sciences
Mutagenic Consequences of the Space Environment

by Yeqing Sun,Marco Durante,Honglu Wu

  • Publisher : Unknown Publisher
  • Release : 2007
  • Pages : 149
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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