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Metabolomics for Biomedical Research

Metabolomics for Biomedical Research
A Book

by Jerzy Adamski

  • Publisher : Academic Press
  • Release : 2020-04
  • Pages : 300
  • ISBN : 0128127848
  • Language : En, Es, Fr & De
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Metabolomics for Biomedical Research brings together recent progress on study design, analytics, biostatistics and bioinformatics for the success of metabolomics research. Metabolomics represents a very interdisciplinary research prominent in the functional analyses of living systems; hence, this book focuses on translation and medical aspects. The book discusses topics such as biomarkers and their requirements to be used in medical research, with the parameters and approaches on how to validate their quality; and animal models and other approaches, as stem cells and organoid culture. Additionally, it explains how metabolomics may be applied in prediction of individual response to drug or disease progression. This book is a valuable source for researchers on systems biology and other members of biomedical field interested in metabolism-oriented studies for medical research.

The Mouse in Biomedical Research

The Mouse in Biomedical Research
A Book

by Anonim

  • Publisher : Academic Press
  • Release : 2007
  • Pages : 1600
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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OMICS

OMICS
Biomedical Perspectives and Applications

by Debmalya Barh,Kenneth Blum,Margaret A. Madigan

  • Publisher : CRC Press
  • Release : 2016-04-19
  • Pages : 622
  • ISBN : 1439850097
  • Language : En, Es, Fr & De
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A reflection of the explosion of research and development in this field, OMICS: Biomedical Perspectives and Applications explores applications of omics in bioinformatics, cancer research and therapy, diabetes research, plant science, molecular biology, and neurosciences. A select editorial panel of experts discusses their cutting edge omics research and novel technologies, supplying a basic platform of methods and applications and a resource for enhanced cross-pollination in a multiomics approach to future endeavors in the fertile fields of omics research. After an introduction on the omics universe, the book presents modern omics and its applications in nanotechnology, genomics, proteomics, metagenomics, toxicogenomics, immunomics, nutrigenomics, diabetes, neurology, cardiology, and cancer to name just a few. The book begins with an overview of omics and omic technologies such as cellomics, glycomics, and lipidomics. It also discusses bioinformatics, demonstrating how it can be a tool in omics, and examines the various approaches of omics technology in toxicology research and applications in biomedical sciences. While there are a long list of omics books available, most focus narrowly on one area. Presenting a wide view of the current status of integrative omics, this resource contains complete coverage of omics in research and therapy, ranging from neuroscience to cardiology. It collates recent developments in the field into a state-of-the-art framework for this discipline.

Novel tools for the investigation of the endogenous role of soluble epoxide hydrolase

Novel tools for the investigation of the endogenous role of soluble epoxide hydrolase
A Book

by John William Newman

  • Publisher : Unknown Publisher
  • Release : 2002
  • Pages : 358
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Metabolite Analysis in Shewanella Oneidensis MR-1 Using Mass Spectrometry

Metabolite Analysis in Shewanella Oneidensis MR-1 Using Mass Spectrometry
A Book

by Sandra Villa

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 148
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Toward Precision Medicine

Toward Precision Medicine
Building a Knowledge Network for Biomedical Research and a New Taxonomy of Disease

by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on A Framework for Developing a New Taxonomy of Disease

  • Publisher : National Academies Press
  • Release : 2012-01-16
  • Pages : 142
  • ISBN : 0309222222
  • Language : En, Es, Fr & De
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Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.

Volatile Organic Compound Analysis in Biomedical Diagnosis Applications

Volatile Organic Compound Analysis in Biomedical Diagnosis Applications
A Book

by Raquel Cumeras,Xavier Correig

  • Publisher : CRC Press
  • Release : 2018-11-09
  • Pages : 272
  • ISBN : 0429782438
  • Language : En, Es, Fr & De
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This volume presents a thought-provoking state-of-the-art picture of how volatile compounds are used in metabolomics, currently a hot topic in the metabolomics field. It provides a thorough description of what volatile organic compounds (VOCs) are, why they are important in biomedicine, and what the analytical platforms are used. It also looks at multivariate analysis and databases needs. Because VOCs are end-up compounds of metabolic processes, volatiles can be linked to different diseases or pathologies for both diagnosis and prognosis. The authors provide authoritative information and guidance on the analytical and statistical techniques used and how to identify, and they review the main current areas of application, which include breath metabolomics, cancer diagnosis, and microbial volatiles. Key Features: Presents a thorough overview of volatile research in biomedical applications Examines both gold standard techniques (metabolomics based) and artificial olfactory systems Reviews all aspects of volatile metabolites in biomedicine research, from origin to detection platforms Describes relevant diseases diagnosis and prognosis achievements, including cancer

International Research Centers Directory

International Research Centers Directory
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2009
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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"A world guide to government, university, independent nonprofit, and commercial research and development centers, institutes, laboratories, bureaus, test facilities, experiment stations, and data collection and analysis centers, as well as foundations, councils and other organizations which support research," [1992/93-].

New Scientist

New Scientist
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2009
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Advances in Gas Chromatography

Advances in Gas Chromatography
A Book

by Xinghua Guo

  • Publisher : BoD – Books on Demand
  • Release : 2014-02-26
  • Pages : 224
  • ISBN : 9535112279
  • Language : En, Es, Fr & De
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For decades gas chromatography has been and will remain an irreplaceable analytical technique in many research areas for both quantitative analysis and qualitative characterization/identification, which is still supplementary with HPLC. This book highlights a few areas where significant advances have been reported recently and/or a revisit of basic concepts is deserved. It provides an overview of instrumental developments, frontline and modern research as well as practical industrial applications. The topics include GC-based metabolomics in biomedical, plant and microbial research, natural products as well as characterization of aging of synthetic materials and industrial monitoring, which are contributions of several experts from different disciplines. It also contains best hand-on practices of sample preparation (derivatization) and data processing in daily research. This book is recommended to both basic and experienced researchers in gas chromatography.

Design and Synthesis of Advanced Materials for Separation Science

Design and Synthesis of Advanced Materials for Separation Science
A Book

by Michael Douglas Slater

  • Publisher : Unknown Publisher
  • Release : 2009
  • Pages : 380
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Genetic Engineering & Biotechnology News

Genetic Engineering & Biotechnology News
GEN.

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2009
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Nature

Nature
A Book

by Sir Norman Lockyer

  • Publisher : Unknown Publisher
  • Release : 2008
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Clinical Proteomics

Clinical Proteomics
From Diagnosis to Therapy

by Jennifer E. Van Eyk,Michael J. Dunn

  • Publisher : Wiley-Blackwell
  • Release : 2008-01-14
  • Pages : 694
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Unparalleled in its scope and depth, this book brings together proteomic approaches in diagnosis and treatment from all clinical fields, including clinical toxicology. The result is a new discipline in molecular medicine that will revolutionize the treatment and prevention of cancer, stroke and other severe diseases. Following an overview of clinical proteomics, the authors look at the technologies available, before moving on to cancer, cardiopulmonary disease, diabetes and stroke. A whole section is devoted to toxicity and the work is rounded off with a discussion of the future of clinical proteomics.

Regression Analysis in Medical Research

Regression Analysis in Medical Research
for Starters and 2nd Levelers

by Ton J. Cleophas,Aeilko H. Zwinderman

  • Publisher : Springer
  • Release : 2018-01-29
  • Pages : 426
  • ISBN : 3319719378
  • Language : En, Es, Fr & De
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This edition is a pretty complete textbook and tutorial for medical and health care students, as well as a recollection/update bench, and help desk for professionals. Novel approaches already applied in published clinical research will be addressed: matrix analyses, alpha spending, gate keeping, kriging, interval censored regressions, causality regressions, canonical regressions, quasi-likelihood regressions, novel non-parametric regressions. Each chapter can be studied as a stand-alone, and covers one field in the fast growing world of regression analyses. The authors, as professors in statistics and machine learning at European universities, are worried, that their students find regression-analyses harder than any other methodology in statistics. This is serious, because almost all of the novel methodologies in current data mining and data analysis include elements of regression-analysis. It is the main incentive for writing this 28 chapter edition, consistent of - 28 major fields of regression analysis, - their condensed maths, - their applications in medical and health research as published so far, - step by step analyses for self-assessment, - conclusion and reference sections. Traditional regression analysis is adequate for epidemiology, but lacks the precision required for clinical investigations. However, in the past two decades modern regression methods have proven to be much more precise. And so it is time, that a book described regression analyses for clinicians. The current edition is the first to do so. It is written for a non-mathematical readership. Self-assessment data-files are provided through Springer' s "Extras Online".

Experimental Biology and Medicine

Experimental Biology and Medicine
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2007
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Database and Expert Systems Applications

Database and Expert Systems Applications
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2003
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Chemical Analysis

Chemical Analysis
A Series of Monographs on Analytical Chemistry and Its Applications

by David D. Cunningham,Julie A. Stenken

  • Publisher : Unknown Publisher
  • Release : 1941
  • Pages : 450
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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The Encyclopedia of Mass Spectrometry

The Encyclopedia of Mass Spectrometry
Volume 8: Hyphenated Methods

by Anonim

  • Publisher : Elsevier Science
  • Release : 2006-11-13
  • Pages : 1000
  • ISBN : 9780080438474
  • Language : En, Es, Fr & De
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Volume 8: Hyphenated Methods Starting with gas chromatography-mass spectrometry (GC-MS) and continuing through GCxGC-MS, LC-MSn, and LC-NMR-MS, hyphenated methods have revolutionized chemical analysis. This volume covers that revolution in two parts. The first (Chapters 1-4) describes principles, instrumentation, and technology, and the second (Chapters 5-10) organizes major application areas in GC-MS and LC-MS. After a general introduction (Chapter 1), attention is paid to principles and instrumentation of GC-MS (Chapter 2) and LC-MS (Chapter 3). Other hyphenated methods, including online combinations of capillary electromigration methods and supercritical fluid chromatography with mass spectrometry, are in Chapter 4. Applications are then covered in the remaining chapters. The application-oriented chapters are focused on the role of mainly LC-MS in the pharmaceutical field (Chapter 5) and biochemical and biotechnological applications (Chapter 10), and the application of both GC-MS and LC-MS in relation to environmental analysis (Chapter 6), food safety and food analysis (Chapter 7), characterization of natural products (Chapter 8), and clinical, toxicological, and forensic analysis (Chapter 9). Covers principles, instrumentation and applications of hyphenated methods involving mass spectrometry Details applications of hyphenated methods in the most important fields Written in the style of tutorials, providing sufficient detail to bring the reader up-to date on the subject area

The Encyclopedia of Mass Spectrometry

The Encyclopedia of Mass Spectrometry
Volume 8: Hyphenated Methods

by Michael L. Gross,Wilfried Niessen,R. M. Caprioli

  • Publisher : Elsevier Science Limited
  • Release : 2006-11-13
  • Pages : 1000
  • ISBN : 9780080438474
  • Language : En, Es, Fr & De
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Presents information on the biographies of recognized pioneers and innovators in the field of mass spectrometry. - Highlights over 120 innovators in mass spectrometry, including several Nobel Prize winners. Discusses instrumentation and their uses, also providing interesting information on the careers, characters, and life stories of the people who did the work. Offers unique insight into the careers and personalities of luminaries in the field.