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Molecular Pathology and the Dynamics of Disease

Molecular Pathology and the Dynamics of Disease
A Book

by Maika G. Mitchell

  • Publisher : Academic Press
  • Release : 2018-04-16
  • Pages : 178
  • ISBN : 0128146117
  • Language : En, Es, Fr & De
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Molecular Pathology and the Dynamics of Disease bridges the basic science of, and primary clinical literature on, human disease. Topics covered include several major disease areas, such as inflammation and host response, vascular disease, obesity, weight regulation and appetite, cancer biology, drug development, and gene- and cell-based therapeutics that are all presented in a way that emphasizes the interplay between clinical care and investigation. As new technologies and techniques are constantly changing and laboratory scientists plays a critical role in validating data used by clinicians in diagnosing patients, this book provides a timely guide that includes a clinical, research and theory perspective. Assimilates theoretical knowledge with practical lab work Provides a needed clinical perspective, along with research and theory Highlights the impact of basic science on the practice of medicine

Pathobiology of Human Disease

Pathobiology of Human Disease
A Dynamic Encyclopedia of Disease Mechanisms

by Anonim

  • Publisher : Elsevier
  • Release : 2014-08-01
  • Pages : 5000
  • ISBN : 0123864577
  • Language : En, Es, Fr & De
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Pathobiology of Human Disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. The work spans more than 48 different biological and medical fields, in five basic sections: Human Organ Systems Molecular Pathology/Basic Mechanisms of Diseases Animal Models/Other Model Systems Experimental Pathology Clinical Pathology Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from research professionals to advanced undergraduate students. Reviews quantitative advances in the imaging and molecular analysis of human tissue, new microarray technologies for analysis of genetic and chromosomal alterations in normal and diseased cells and tissues, and new transgenic models of human disease using conditional, tissue-specific gene targeting Articles link through to relevant virtual microscopy slides, illustrating side-by-side presentation of "Normal" and "Disease" anatomy and histology images Fully-annotated with many supplementary full color images, graphs, tables, and video files linked to data sets and to live references, enabling researchers to delve deeper and visualize solutions

Rhizoctonia Species: Taxonomy, Molecular Biology, Ecology, Pathology and Disease Control

Rhizoctonia Species: Taxonomy, Molecular Biology, Ecology, Pathology and Disease Control
A Book

by B. Sneh,S. Jabaji-Hare,S.M. Neate,G. Dijst

  • Publisher : Springer Science & Business Media
  • Release : 2013-06-29
  • Pages : 578
  • ISBN : 9401729018
  • Language : En, Es, Fr & De
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Rhizoctonia Species: Taxonomy, Molecular Biology, Ecology, Pathology and Control, written by the world's most reputable experts in their respective fields of Rhizoctonia research, summarizes years of research in the various aspects of the ubiquitous complex group of soil-borne fungi belonging to the anamorph genus Rhizoctonia. Species of Rhizoctonia worldwide cause economically important diseases on most of the world's important plants such as cereals, potato, cotton, sugarbeet, vegetables, ornamentals and trees in nurseries. The subject reviews covered in the book include classic as well as modern approaches to Rhizoctonia research in: Taxonomy and Evolution, Genetics and Pathogenicity, Plant-Rhizoctonia Interactions, Ecology, Population and Disease Dynamics, Disease Occurrence and Management in Various Crops, Cultural Control, Biological Control, Germplasm for Resistance, Chemical and Integrated Control Strategies. It aims to be the standard reference source book on Rhizoctonia for the next decade or more, just as Parmeter et al. (1970) has been in the past. It will be an important publication for Rhizoctonia investigators, plant pathologists, students, extension specialists, crop producers and companies dealing with plant disease control.

Precision Molecular Pathology of Glioblastoma

Precision Molecular Pathology of Glioblastoma
A Book

by José Javier Otero

  • Publisher : Springer Nature
  • Release : 2021
  • Pages : 129
  • ISBN : 3030691705
  • Language : En, Es, Fr & De
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Hematologic Cancers: From Molecular Pathobiology to Targeted Therapeutics

Hematologic Cancers: From Molecular Pathobiology to Targeted Therapeutics
A Book

by Jianguo Tao,Eduardo Sotomayor

  • Publisher : Springer Science & Business Media
  • Release : 2012-11-13
  • Pages : 426
  • ISBN : 9400750285
  • Language : En, Es, Fr & De
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In the last decade, there has been a remarkable explosion of knowledge in hematologic cancer from basic molecular biology and pathology to clinical therapy. This has led to many new advance and insights in the understanding of pathobiology of malignant hematology. New knowledge of disease molecular pathology, cytogenetic, epigenetic and genomic alterations have provided new strategies to attack and eradicate tumor cells at molecular level and significantly impacted our current therapeutics for hematological malignancies. The recent and ongoing rapid expansion of knowledge in this area has become extensive, dynamic and diffuse over the literature and research publications. This has led to the need to capture and compile the new and current information about hematologic cancer with special emphasis on translation from molecular pathobiology to targeted therapeutics. In this book experts from around the world share their thoughts and knowledge about the pathobiology of hematologic cancer, as well as their view on current treatment approaches and future development in these malignant hematologic diseases. This book is well suited for hematology residents, fellows and hematology-oncology physicians, hematopathologist as well as basic research scientist in the area of hematologic malignancies.

Molecular Pathology of Neoplastic Gastrointestinal Diseases

Molecular Pathology of Neoplastic Gastrointestinal Diseases
A Book

by Antonia R. Sepulveda,John P. Lynch

  • Publisher : Springer Science & Business Media
  • Release : 2013-01-28
  • Pages : 277
  • ISBN : 1461460158
  • Language : En, Es, Fr & De
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Molecular Pathology of Neoplastic Gastrointestinal Diseases reviews the molecular aspects that characterize the spectrum of neoplastic conditions that affect the gastrointestinal tract, providing the reader with current up-to-date knowledge. For each disease entity chapters provide reviews on: the molecular basis of the individual disease molecular testing approaches currently available or in development for diagnosis or for gene target characterization for selective targeted therapies recommended guidelines for clinical application of molecular tests are included whenever available molecular testing for hereditary predisposition or disease risk animal models and cell culture models of disease

The Molecular Pathology of Autoimmune Diseases

The Molecular Pathology of Autoimmune Diseases
A Book

by Argyrios N Theofilopoulos,Constantin A. Bona

  • Publisher : CRC Press
  • Release : 2002-12-06
  • Pages : 1200
  • ISBN : 1482283727
  • Language : En, Es, Fr & De
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Remarkable advances have been made in the pathogenesis of autoimmunity, such as with bone marrow transplantation, which is becoming a powerful strategy in treating certain life-threatening diseases. The Molecular Pathology of Autoimmune Diseases is a concise and centralized resource for information on the topic, with a special focus on the molecula

Essential Concepts in Molecular Pathology

Essential Concepts in Molecular Pathology
A Book

by William B. Coleman,Gregory J. Tsongalis

  • Publisher : Academic Press
  • Release : 2019-11-23
  • Pages : 634
  • ISBN : 0128132582
  • Language : En, Es, Fr & De
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Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology

Advances in Molecular Pathology, E-Book 2019

Advances in Molecular Pathology, E-Book 2019
A Book

by Gregory J. Tsongalis

  • Publisher : Elsevier Health Sciences
  • Release : 2019-11-06
  • Pages : 129
  • ISBN : 0323709516
  • Language : En, Es, Fr & De
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This issue of Advances in Molecular Pathology will provide a comprehensive review of the most current practices, trends, and developments in the field of Molecular Pathology. Publishing on an annual basis, the volume will be divided into 7 sections: Genetics, Hematopathology, Infectious Disease, Pharmacogenomics, Informatics, Solid tumors, and Identity/HLA. Led by Dr. Gregory Tsongalis of Dartmouth University, a team of experienced pathologists from institutions across the country oversee annual topic and expert author selection.

Neurology

Neurology
Proceedings of the XIIIth World Congress of Neurology Hamburg, September 1–6, 1985

by Klaus Poeck,Hans-Joachim Freund,Heinz Gänshirt

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 498
  • ISBN : 3642700071
  • Language : En, Es, Fr & De
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Molecular Pathology

Molecular Pathology
The Molecular Basis of Human Disease

by William B. Coleman,Gregory J. Tsongalis

  • Publisher : Academic Press
  • Release : 2017-11-09
  • Pages : 802
  • ISBN : 0128027878
  • Language : En, Es, Fr & De
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As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

Advances in Molecular Pathology 2018

Advances in Molecular Pathology 2018
A Book

by Anonim

  • Publisher : Elsevier Health Sciences
  • Release : 2018-10-09
  • Pages : 264
  • ISBN : 0323639666
  • Language : En, Es, Fr & De
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This inaugural issue of Advances in Molecular Pathology will provide a comprehensive review of the most current practices, trends, and developments in the field of Molecular Pathology. Publishing on an annual basis, the volume will be divided into 7 sections: Genetics, Hematopathology, Infectious Disease, Pharmacogenomics, Informatics, Solid tumors, and Identity/HLA. Led by Dr. Gregory Tsongalis of Dartmouth University, a team of experienced pathologists from institutions across the country oversee annual topic and expert author selection. Topics discussed in this volume include, but are not limited to: whole genome sequencing in critically ill children, bioinformatics in clinical genomic sequencing, comprehensive monitoring of patients with chronic myeloid leukemia, genetic biomarkers in the biology and clinical workup of chronic lymphocytic leukemia, metagenomics in infectious disease, point of care molecular testing, pharmacogenomics in oncology, clinical uses of panel testing vs. single gene testing, large scale data sharing initiatives in genomic oncology, clinical NGS assays for solid tumors emerging concepts in liquid biopsy the cell line and tissue misidentification problem, and cell line detective work.

Molecular Pathology of Liver Diseases

Molecular Pathology of Liver Diseases
A Book

by Satdarshan P. S. Monga

  • Publisher : Springer Science & Business Media
  • Release : 2010-12-14
  • Pages : 931
  • ISBN : 9781441971074
  • Language : En, Es, Fr & De
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Cellular and Molecular Pathology of the Liver is extensive, complex and ranges from the understanding the basic molecular mechanisms that dictate everything from liver homeostasis to liver disease. Molecular Pathology of the liver is complicated due to some of the important functions inherent and unique to the Liver, including its innate ability to regenerate and the multitude of functions it plays for the wellbeing of an organism. With all this in mind, Molecular Pathology of Liver Diseases is organized in different sections, which will coherently and cohesively present the molecular basis of hepatic physiology and pathology. The first two sections are key to understanding the liver anatomy and physiology at a cellular level and go on to define the molecular mechanics in various liver cell types. These sections also cover the existing paradigms in liver development, regeneration and growth. The next section is key to understanding the Molecular Pathology unique to liver diseases and associated phenotypes. The final sections are geared towards the existing knowledge of the molecular basis of many common and uncommon liver diseases in both neoplastic and non-neoplastic areas including pathologies associated with intra-hepatic and extra-hepatic biliary tree. Thus, this textbook is a one-stop reference for comprehending the molecular mechanisms of hepatic pathobiology. It is clearly unique in its format, readability and information and thus will be an asset to many in the field of Pathology and other disciplines.

Research Communications in Molecular Pathology and Pharmacology

Research Communications in Molecular Pathology and Pharmacology
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1998
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Molecular Pathology of Lung Diseases

Molecular Pathology of Lung Diseases
A Book

by Dani S. Zander,Helmut Popper,Jaishree Jagirdar,Abida Haque,Roberto Barrios

  • Publisher : Springer Science & Business Media
  • Release : 2010-05-26
  • Pages : 682
  • ISBN : 0387724303
  • Language : En, Es, Fr & De
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This major work, complete with 150 illustrations, many of them in color, bridges the gap between clinical pulmonary pathology and basic molecular science. Through a highly visual approach that features an abundance of tables and diagrams, the book offers a practical disease-based overview. The first two sections of the volume provide the reader with general concepts, terminology and procedures in molecular pathology. The remainder of the volume is subdivided into neoplastic and non-neoplastic lung diseases with detailed chapters covering the current molecular pathology of specific diseases. The book will be essential reading for pathologists, pulmonologists, thoracic surgeons and other health care providers interested in lung disease.

Molecular Pathology

Molecular Pathology
A Book

by Antoni Horst

  • Publisher : CRC Press
  • Release : 2018-05-04
  • Pages : 474
  • ISBN : 1351083228
  • Language : En, Es, Fr & De
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This book provides modern views of developments in medical sciences based on advances in molecular pathology. Topics discussed include the molecule; the genome of eukaryotes and its function; gene regulation; the proteins; molecular aspects of inflammation, immunology, and carcinogenesis; molecular biology of the nervous system; molecular defects in the endocrine system; molecular diseases of the blood and blood-forming tissues; and diagnosis of molecular diseases. Four tables and 75 figures illustrate the concepts and provide a quick means to reference important data. Immunologists, pathologists, geneticists, and all other researchers in the biological and medical sciences will find a wealth of information in this ground-breaking new book.

Molecular Pathology in Clinical Practice

Molecular Pathology in Clinical Practice
A Book

by Debra G.B. Leonard

  • Publisher : Springer
  • Release : 2016-02-02
  • Pages : 1001
  • ISBN : 331919674X
  • Language : En, Es, Fr & De
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This authoritative textbook offers in-depth coverage of all aspects of molecular pathology practice and embodies the current standard in molecular testing. Since the successful first edition, new sections have been added on pharmacogenetics and genomics, while other sections have been revised and updated to reflect the rapid advances in the field. The result is a superb reference that encompasses molecular biology basics, genetics, inherited cancers, solid tumors, neoplastic hematopathology, infectious diseases, identity testing, HLA typing, laboratory management, genomics and proteomics. Throughout the text, emphasis is placed on the molecular variations being detected, the clinical usefulness of the tests and important clinical and laboratory issues. The second edition of Molecular Pathology in Clinical Practice will be an invaluable source of information for all practicing molecular pathologists and will also be of utility for other pathologists, clinical colleagues and trainees.

Advances in Molecular Pathology, E-Book

Advances in Molecular Pathology, E-Book
A Book

by Gregory J. Tsongalis

  • Publisher : Elsevier Health Sciences
  • Release : 2020-11-07
  • Pages : 240
  • ISBN : 032372227X
  • Language : En, Es, Fr & De
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This issue of Advances in Molecular Pathology will provide a comprehensive review of the most current practices, trends, and developments in the field of Molecular Pathology. Publishing on an annual basis, the volume will be divided into 7 sections: Genetics, Hematopathology, Infectious Disease, Pharmacogenomics, Informatics, Solid tumors, and Identity/HLA. Led by Dr. Gregory Tsongalis of Dartmouth University, a team of experienced pathologists from institutions across the country oversee annual topic and expert author selection.

Diagnostic Molecular Pathology

Diagnostic Molecular Pathology
A Guide to Applied Molecular Testing

by William B. Coleman,Gregory J. Tsongalis

  • Publisher : Academic Press
  • Release : 2016-10-05
  • Pages : 582
  • ISBN : 0128011572
  • Language : En, Es, Fr & De
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Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). In each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms. Sections are dedicated to general methodologies employed in testing (to convey the concepts reflected in the methods), and specific description of how these methods can be applied and are applied to specific diseases are described. The book does not present molecular methods in isolation, but considers how other evidence (symptoms, radiology or other imaging, or other clinical tests) is used to guide the selection of molecular tests or how these other data are used in conjunction with molecular tests to make diagnoses (or otherwise contribute to clinical workup). In addition, final chapters look to the future (new technologies, new approaches) of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests. Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing contains exercises to test readers on their understanding of how molecular diagnostic tests are utilized and the value of the information that can be obtained in the context of the patient workup. Readers are directed to an ancillary website that contains supplementary materials in the form of exercises where decision trees can be employed to simulate actual clinical decisions. Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis, and classification in the clinical workup of a patient Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for prognostication of disease Features an ancillary website with self-testing exercises where decision trees can be employed to simulate actual clinical decisions Highlights new technologies and approaches of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests

Biomedical Index to PHS-supported Research: pt. A. Subject access A-H

Biomedical Index to PHS-supported Research: pt. A. Subject access A-H
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 1993
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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