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Multidisciplinary Microfluidic and Nanofluidic Lab-on-a-Chip

Multidisciplinary Microfluidic and Nanofluidic Lab-on-a-Chip
Principles and Applications

by Xiujun James Li,Chaoyong Yang,Paul C. H. Li

  • Publisher : Newnes
  • Release : 2021-09-24
  • Pages : 484
  • ISBN : 0444594612
  • Language : En, Es, Fr & De
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Multidisciplinary Microfluidic and Nanofluidic Lab-on-a-Chip: Principles and Applications provides chemists, biophysicists, engineers, life scientists, biotechnologists, and pharmaceutical scientists with the principles behind the design, manufacture, and testing of life sciences microfluidic systems. This book serves as a reference for technologies and applications in multidisciplinary areas, with an emphasis on quickly developing or new emerging areas, including digital microfluidics, nanofluidics, papers-based microfluidics, and cell biology. The book offers practical guidance on how to design, analyze, fabricate, and test microfluidic devices and systems for a wide variety of applications including separations, disease detection, cellular analysis, DNA analysis, proteomics, and drug delivery. Calculations, solved problems, data tables, and design rules are provided to help researchers understand microfluidic basic theory and principles and apply this knowledge to their own unique designs. Recent advances in microfluidics and microsystems for life sciences are impacting chemistry, biophysics, molecular, cell biology, and medicine for applications that include DNA analysis, drug discovery, disease research, and biofluid and environmental monitoring. Provides calculations, solved problems, data tables and design rules to help understand microfluidic basic theory and principles Gives an applied understanding of the principles behind the design, manufacture, and testing of microfluidic systems Emphasizes on quickly developing and emerging areas, including digital microfluidics, nanofluidics, papers-based microfluidics, and cell biology

Microfluidic Devices for Biomedical Applications

Microfluidic Devices for Biomedical Applications
A Book

by Xiujun James Li,Yu Zhou

  • Publisher : Woodhead Publishing
  • Release : 2021-08-09
  • Pages : 722
  • ISBN : 0128227559
  • Language : En, Es, Fr & De
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Microfluidic Devices for Biomedical Applications, Second Edition provides updated coverage on the fundamentals of microfluidics, while also exploring a wide range of medical applications. Chapters review materials and methods, microfluidic actuation mechanisms, recent research on droplet microfluidics, applications in drug discovery and controlled-delivery, including micro needles, consider applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds, and cover the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis. This book is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries. Discusses the fundamentals of microfluidics or lab-on-a-chip (LOC) and explores a wide range of medical applications Considers materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies Details applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and its role in developing tissue scaffolds, and stem cell engineering

Microfluidics and Nanofluidics Handbook

Microfluidics and Nanofluidics Handbook
Chemistry, Physics, and Life Science Principles

by Sushanta K. Mitra,Suman Chakraborty

  • Publisher : CRC Press
  • Release : 2011-09-20
  • Pages : 1132
  • ISBN : 1439816778
  • Language : En, Es, Fr & De
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The Microfluidics and Nanofluidics Handbook: Two-Volume Set comprehensively captures the cross-disciplinary breadth of the fields of micro- and nanofluidics, which encompass the biological sciences, chemistry, physics and engineering applications. To fill the knowledge gap between engineering and the basic sciences, the editors pulled together key individuals, well known in their respective areas, to author chapters that help graduate students, scientists, and practicing engineers understand the overall area of microfluidics and nanofluidics. Topics covered include Cell Lysis Techniques in Lab-on-a-Chip Technology Electrodics in Electrochemical Energy Conversion Systems: Microstructure and Pore-Scale Transport Microscale Gas Flow Dynamics and Molecular Models for Gas Flow and Heat Transfer Microscopic Hemorheology and Hemodynamics Covering physics and transport phenomena along with life sciences and related applications, Volume One: Chemistry, Physics, and Life Science Principles provides readers with the fundamental science background that is required for the study of microfluidics and nanofluidics. Both volumes include as much interdisciplinary knowledge as possible to reflect the inherent nature of this area, valuable to students and practitioners.

CMOS Capacitive Sensors for Lab-on-Chip Applications

CMOS Capacitive Sensors for Lab-on-Chip Applications
A Multidisciplinary Approach

by Ebrahim Ghafar-Zadeh,Mohamad Sawan

  • Publisher : Springer Science & Business Media
  • Release : 2010-03-10
  • Pages : 146
  • ISBN : 9789048137275
  • Language : En, Es, Fr & De
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1.1 Overview of Lab-on-Chip Laboratory-on-Chip (LoC) is a multidisciplinary approach used for the miniaturization, integration and automation of biological assays or procedures in analytical chemistry [1–3]. Biology and chemistry are experimental sciences that are continuing to evolve and develop new protocols. Each protocol offers step-by-step laboratory instructions, lists of the necessary equipments and required biological and/or chemical substances [4–7]. A biological or chemical laboratory contains various pieces of equipment used for performing such protocols and, as shown in Fig. 1.1, the engineering aspect of LoC design is aiming to embed all these components in a single chip for single-purpose applications. 1.1.1 Main Objectives of LoC Systems Several clear advantages of this technology over conventional approaches, including portability, full automation, ease of operation, low sample consumption and fast assays time, make LoC suitable for many applications including. 1.1.1.1 Highly Throughput Screening To conduct an experiment, a researcher fills a well with the required biological or chemical analytes and keeps the sample in an incubator for some time to allowing the sample to react properly. Afterwards, any changes can be observed using a microscope. In order to quickly conduct millions of biochemical or pharmacolo- cal tests, the researchers will require an automated highly throughput screening (HTS) [8], comprised of a large array of wells, liquid handling devices (e.g., mic- channel, micropump and microvalves [9–11]), a fully controllable incubator and an integrated sensor array, along with the appropriate readout system.

Nanospectrum: A Current Scenario

Nanospectrum: A Current Scenario

by Prof. (Dr.) Sampa Chakrabarti,Dr. Prasun Mukherjee,Dr. Gobinda Gopal Khan,Dr. Arghya Adhikary,Dr. Prasun Patra,Dr. Jayanta Kumar Bal

  • Publisher : Allied Publishers
  • Release : 2016-04-18
  • Pages : 164
  • ISBN : 9385926063
  • Language : En, Es, Fr & De
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Centre for Research in Nanoscience and Nanotechnology (CRNN), University of Calcutta organized a national conference, NS&NT-2014 in the year 2014. This volume compiles a few papers presented in the conference as well as reviews from experts received after the conference. This is therefore not a conference proceeding, but an outcome of the conference. The compiled papers break the boundaries of subjects and disciplines and hence are expected to be interesting to all working in the field of Nanoscience and Nanotechnology. This collection is also indicative of the present direction of research in nanotechnology by the researchers of the university and their collaborators.

The Immunoassay Handbook

The Immunoassay Handbook
Theory and Applications of Ligand Binding, ELISA and Related Techniques

by David Wild

  • Publisher : Newnes
  • Release : 2013-01-21
  • Pages : 1036
  • ISBN : 0080970389
  • Language : En, Es, Fr & De
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The fourth edition of The Immunoassay Handbook provides an excellent, thoroughly updated guide to the science, technology and applications of ELISA and other immunoassays, including a wealth of practical advice. It encompasses a wide range of methods and gives an insight into the latest developments and applications in clinical and veterinary practice and in pharmaceutical and life science research. Highly illustrated and clearly written, this award-winning reference work provides an excellent guide to this fast-growing field. Revised and extensively updated, with over 30% new material and 77 chapters, it reveals the underlying common principles and simplifies an abundance of innovation. The Immunoassay Handbook reviews a wide range of topics, now including lateral flow, microsphere multiplex assays, immunohistochemistry, practical ELISA development, assay interferences, pharmaceutical applications, qualitative immunoassays, antibody detection and lab-on-a-chip. This handbook is a must-read for all who use immunoassay as a tool, including clinicians, clinical and veterinary chemists, biochemists, food technologists, environmental scientists, and students and researchers in medicine, immunology and proteomics. It is an essential reference for the immunoassay industry. Provides an excellent revised guide to this commercially highly successful technology in diagnostics and research, from consumer home pregnancy kits to AIDS testing. www.immunoassayhandbook.com is a great resource that we put a lot of effort into. The content is designed to encourage purchases of single chapters or the entire book. David Wild is a healthcare industry veteran, with experience in biotechnology, pharmaceuticals, medical devices and immunodiagnostics, which remains his passion. He worked for Amersham, Eastman-Kodak, Johnson & Johnson, and Bristol-Myers Squibb, and consulted for diagnostics and biotechnology companies. He led research and development programs, design and construction of chemical and biotechnology plants, and integration of acquired companies. Director-level positions included Research and Development, Design Engineering, Operations and Strategy, for billion dollar businesses. He retired from full-time work in 2012 to focus on his role as Editor of The Immunoassay Handbook, and advises on product development, manufacturing and marketing. Provides a unique mix of theory, practical advice and applications, with numerous examples Offers explanations of technologies under development and practical insider tips that are sometimes omitted from scientific papers Includes a comprehensive troubleshooting guide, useful for solving problems and improving assay performancee Provides valuable chapter updates, now available on www.immunoassayhandbook.com

Advances in Microfluidics and Nanofluids

Advances in Microfluidics and Nanofluids
A Book

by S. M. Sohel Murshed

  • Publisher : BoD – Books on Demand
  • Release : 2021-07-07
  • Pages : 190
  • ISBN : 1839686928
  • Language : En, Es, Fr & De
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Microfluidics and nanofluids are rapidly growing technologies of tremendous potential and benefits. This book features a spectrum of topics on these emerging technologies that include microfluidic applications, mass production of chips, flow sensing approaches, fabrication of microfluidic channels using the micromilling process, application of micromixers for wastewater treatment and life cycle assessment, solar thermal conversion of plasmonic nanofluids, and liquid cooling, as well as carbon capture utilization and storage using nanocomposite and nanofluids. The book is intended to provide useful information and guidance to a wide variety of people including students, researchers, engineers, and manufacturers who are involved or interested in these technologies.

Optical MEMS, Nanophotonics, and Their Applications

Optical MEMS, Nanophotonics, and Their Applications
A Book

by Guangya Zhou,Chengkuo Lee

  • Publisher : CRC Press
  • Release : 2017-12-14
  • Pages : 432
  • ISBN : 1498741347
  • Language : En, Es, Fr & De
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This book covers device design fundamentals and system applications in optical MEMS and nanophotonics. Expert authors showcase examples of how fusion of nanoelectromechanical (NEMS) with nanophotonic elements is creating powerful new photonic devices and systems including MEMS micromirrors, MEMS tunable filters, MEMS-based adjustable lenses and apertures, NEMS-driven variable silicon nanowire waveguide couplers, and NEMS tunable photonic crystal nanocavities. The book also addresses system applications in laser scanning displays, endoscopic systems, space telescopes, optical telecommunication systems, and biomedical implantable systems. Presents efforts to scale down mechanical and photonic elements into the nano regime for enhanced performance, faster operational speed, greater bandwidth, and higher level of integration. Showcases the integration of MEMS and optical/photonic devices into real commercial products. Addresses applications in optical telecommunication, sensing, imaging, and biomedical systems. Prof. Vincent C. Lee is Associate Professor in the Department of Electrical and Computer Engineering, National University of Singapore. Prof. Guangya Zhou is Associate Professor in the Department of Mechanical Engineering at National University of Singapore.

Microdroplet Technology

Microdroplet Technology
Principles and Emerging Applications in Biology and Chemistry

by Philip Day,Andreas Manz,Yonghao Zhang

  • Publisher : Springer Science & Business Media
  • Release : 2012-07-28
  • Pages : 246
  • ISBN : 1461432650
  • Language : En, Es, Fr & De
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Microdroplet technology has recently emerged to provide new and diverse applications via microfluidic functionality, especially in various areas of biology and chemistry. This book, then, gives an overview of the principle components and wide-ranging applications for state-of-the-art of droplet-based microfluidics. Chapter authors are internationally-leading researchers from chemistry, biology, physics and engineering that present various key aspects of micrdroplet technology -- fundamental flow physics, methodology and components for flow control, applications in biology and chemistry, and a discussion of future perspectives. This book acts as a reference for academics, post-graduate students, and researcher wishing to deepen their understand of microfluidics and introduce optimal design and operation of new droplet-based microfluidic devices for more comprehensive analyte assessments.

The Nano Age of Digital Immunity Infrastructure Fundamentals and Applications

The Nano Age of Digital Immunity Infrastructure Fundamentals and Applications
The Intelligent Cyber Shield for Smart Cities

by Rocky Termanini

  • Publisher : CRC Press
  • Release : 2018-03-05
  • Pages : 489
  • ISBN : 1351682873
  • Language : En, Es, Fr & De
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Present anti-virus technologies do not have the symmetrical weaponry to defeat massive DDoS attacks on smart cities. Smart cities require a new set of holistic and AI-centric cognitive technology, such as autonomic components that replicate the human immune system, and a smart grid that connects all IoT devices. The book introduces Digital Immunity and covers the human immune system, massive distributed attacks (DDoS) and the future generations cyber attacks, the anatomy and critical success factors of smart city, Digital Immunity and the role of the Smart Grid, how Digital Immunity defends the smart city and annihilates massive malware, and Digital Immunity to combat global cyber terrorism.

MEMS

MEMS
Design and Fabrication

by Mohamed Gad-el-Hak

  • Publisher : CRC Press
  • Release : 2005-11-29
  • Pages : 664
  • ISBN : 1420036564
  • Language : En, Es, Fr & De
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As our knowledge of microelectromechanical systems (MEMS) continues to grow, so does The MEMS Handbook. The field has changed so much that this Second Edition is now available in three volumes. Individually, each volume provides focused, authoritative treatment of specific areas of interest. Together, they comprise the most comprehensive collection of MEMS knowledge available, packaged in an attractive slipcase and offered at a substantial savings. This best-selling handbook is now more convenient than ever, and its coverage is unparalleled. The second volume, MEMS: Design and Fabrication, details the techniques, technologies, and materials involved in designing and fabricating MEMS devices. It begins with an overview of MEMS materials and then examines in detail various fabrication and manufacturing methods, including LIGA and macromolding, X-ray based fabrication, EFAB® technology, and deep reactive ion etching. This book includes three new chapters on polymeric-based sensors and actuators, diagnostic tools, and molecular self-assembly. It is a thorough guide to the important aspects of design and fabrication. MEMS: Design and Fabrication comprises contributions from the foremost experts in their respective specialties from around the world. Acclaimed author and expert Mohamed Gad-el-Hak has again raised the bar to set a new standard for excellence and authority in the fledgling fields of MEMS and nanotechnology.

Microfabrication for Industrial Applications

Microfabrication for Industrial Applications
A Book

by Regina Luttge

  • Publisher : William Andrew
  • Release : 2011-08-31
  • Pages : 312
  • ISBN : 081551977X
  • Language : En, Es, Fr & De
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This book focuses on the industrial perspective for micro- and nanofabrication methods including large-scale manufacturing, transfer of concepts from lab to factory, process tolerance, yield, robustness, and cost. It gives a history of miniaturization, micro- and nanofabrication, and surveys industrial fields of application, illustrating fabrication processes of relevant micro and nano devices. Concerning sub-micron feature manufacture, the book explains: the philosophy of micro/ nanofabrication for integrated circuit industry; thin film deposition; (waveguide, plastic, semiconductor) material processing; packaging; interconnects; stress (e.g., thin film residual); economic; and environmental aspects. Micro/nanomechanical sensors and actuators are explained in depth with information on applications, materials (incl. functional polymers), methods, testing, fabrication, integration, reliability, magnetic microstructures, etc. Shows engineers & students how to evaluate the potential value of current and nearfuture manufacturing processes for miniaturized systems in industrial environments Explains the top-down and bottom up approaches to nanotechnology, nanostructures fabricated with beams, nano imprinting methods, nanoparticle manufacturing (and their health aspects), nanofeature analysis, and connecting nano to micro to macro Discusses issues for practical application cases; possibilities of dimension precision; large volume manufacturing of micro- & nanostructures (machines, materials, costs) Explains applications of Microsystems for information technology, e.g.: data recording (camera, microphone), storage (memories, CDs), communication; computing; and displays (beamers, LCD, TFT) Case studies are given for sensors, resonators, probes, transdermal medical systems, micro- pumps & valves, inkjets, DNA-analysis, lab-on-a-chip, & micro-cooling

Alternative Lithography

Alternative Lithography
Unleashing the Potentials of Nanotechnology

by Clivia M. Sotomayor Torres

  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • Pages : 333
  • ISBN : 1441992049
  • Language : En, Es, Fr & De
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Good old Gutenberg could not have imagined that his revolutionary printing concept which so greatly contributed to dissemination of knowledge and thus today 's wealth, would have been a source of inspiration five hundred years later. Now, it seems intuitive that a simple way to produce a large number of replicates is using a mold to emboss pattern you need, but at the nanoscale nothing is simple: the devil is in the detail. And this book is about the "devil". In the following 17 chapters, the authors-all of them well recognized and active actors in this emerging field-describe the state-of-the-art, today 's technological bottlenecks and the prospects for micro-contact printing and nanoimprint lithography. Many results of this book originate from projects funded by the European Com mission through its "Nanotechnology Information Devices" (NID) initiative. NID was launched with the objective to develop nanoscale devices for the time when the red brick scenario of the ITRS roadmap would be reached. It became soon clear however, that there was no point to investigate only alternative devices to CMOS, but what was really needed was an integrated approach that took into account more facets of this difficult undertaking. Technologically speaking , this meant to have a coherent strategy to develop novel devices, nanofabrication tools and circuit & system architectures at the same time.

Micro- and Nanofluidics for Bionanoparticle Analysis

Micro- and Nanofluidics for Bionanoparticle Analysis
A Book

by Yong Zeng,Xuanhong Cheng

  • Publisher : Unknown Publisher
  • Release : 2019
  • Pages : 1
  • ISBN : 9783039215959
  • Language : En, Es, Fr & De
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Bionanoparticles such as microorganisms and exosomes are recoganized as important targets for clinical applications, food safety, and environmental monitoring. Other nanoscale biological particles, includeing liposomes, micelles, and functionalized polymeric particles are widely used in nanomedicines. The recent deveopment of microfluidic and nanofluidic technologies has enabled the separation and anslysis of these species in a lab-on-a-chip platform, while there are still many challenges to address before these analytical tools can be adopted in practice. For example, the complex matrices within which these species reside in create a high background for their detection. Their small dimension and often low concentration demand creative strategies to amplify the sensing signal and enhance the detection speed. This Special Issue aims to recruit recent discoveries and developments of micro- and nanofluidic strategies for the processing and analysis of biological nanoparticles. The collection of papers will hopefully bring out more innovative ideas and fundamental insights to overcome the hurdles faced in the separation and detection of bionanoparticles.

Who's Who in Science and Engineering 2008-2009

Who's Who in Science and Engineering 2008-2009
A Book

by Marquis Who's Who, Inc.

  • Publisher : Marquis Whos Who
  • Release : 2007-12
  • Pages : 2438
  • ISBN : 9780837957685
  • Language : En, Es, Fr & De
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Micro/Nano Devices for Blood Analysis

Micro/Nano Devices for Blood Analysis
A Book

by Rui A. Lima,Graça Minas,Susana Catarino

  • Publisher : Unknown Publisher
  • Release : 2019
  • Pages : 174
  • ISBN : 9783039218257
  • Language : En, Es, Fr & De
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The development of micro- and nanodevices for blood analysis is an interdisciplinary subject that demands the integration of several research fields, such as biotechnology, medicine, chemistry, informatics, optics, electronics, mechanics, and micro/nanotechnologies. Over the last few decades, there has been a notably fast development in the miniaturization of mechanical microdevices, later known as microelectromechanical systems (MEMS), which combine electrical and mechanical components at a microscale level. The integration of microflow and optical components in MEMS microdevices, as well as the development of micropumps and microvalves, have promoted the interest of several research fields dealing with fluid flow and transport phenomena happening in microscale devices. Microfluidic systems have many advantages over their macroscale counterparts, offering the ability to work with small sample volumes, providing good manipulation and control of samples, decreasing reaction times, and allowing parallel operations in one single step. As a consequence, microdevices offer great potential for the development of portable and point-of-care diagnostic devices, particularly for blood analysis. Moreover, the recent progress in nanotechnology has contributed to its increasing popularity, and has expanded the areas of application of microfluidic devices, including in the manipulation and analysis of flows on the scale of DNA, proteins, and nanoparticles (nanoflows). In this Special Issue, we invited contributions (original research papers, review articles, and brief communications) that focus on the latest advances and challenges in micro- and nanodevices for diagnostics and blood analysis, micro- and nanofluidics, technologies for flow visualization, MEMS, biochips, and lab-on-a-chip devices and their application to research and industry. We hope to provide an opportunity to the engineering and biomedical community to exchange knowledge and information and to bring together researchers who are interested in the general field of MEMS and micro/nanofluidics and, especially, in its applications to biomedical areas.

CMOS Biotechnology

CMOS Biotechnology
A Book

by Hakho Lee,Donhee Ham,Robert M. Westervelt

  • Publisher : Springer Science & Business Media
  • Release : 2007-05-04
  • Pages : 385
  • ISBN : 0387689133
  • Language : En, Es, Fr & De
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Lately, there has been a growing interest in exploiting the benefits of the ICs for areas outside of the traditional application spaces. One noteable area is found in biology Bioanalytical instruments have been miniaturized on ICs to study various biophenomena or to actuate biosystems. These biolab-on-IC systems utilize the IC to facilitate faster, repeatable, and standardized biological experiments at low cost with a small volume of biological sample. The research activities in this field are expected to enjoy substantial growth in the foreseeable future. BioCMOS Technologies reviews these exciting recent efforts in joining CMOS technology with biology.

Dissertation Abstracts International

Dissertation Abstracts International
The sciences and engineering. B

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2006
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Nanosystems Design and Technology

Nanosystems Design and Technology
A Book

by Giovanni DeMicheli,Yusuf Leblebici,Martin Gijs,Janos Vörös

  • Publisher : Springer Science & Business Media
  • Release : 2009-09-01
  • Pages : 177
  • ISBN : 9781441902559
  • Language : En, Es, Fr & De
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Nanosystems use new, nanoscopic electrical and/or mechanical devices which, as constituents of electronic and electromechanical systems, find application primarily in computing, embedded control and biomedical data acquisition. In particular, this book will deal with the characterization and patterning of these materials from an engineering perspective, with the objective of creating operational prototypes and products. The book will integrate various nano technologies on materials, devices and systems and identify key areas and results. The book will describe different design aspects for integrated systems on silicon, as well as on heterogeneous platforms including, but not limited to, electrical, optical, micromechanical and biological components in various forms and mixtures. By associating research topics from differing horizons, the book will provide a unique opportunity to bridge the gap between electronics/electrical engineering and materials science. The book will include topics at the intersection of these disciplines, and will interface with computer science, biology and medicine.

Innovations in Engineering Education

Innovations in Engineering Education
Presented at ... ASME International Mechanical Engineering Congress and Exposition

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2007
  • Pages : 129
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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