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Multifunctional Theranostic Nanomedicines in Cancer

Multifunctional Theranostic Nanomedicines in Cancer
A Book

by Malay K. Das

  • Publisher : Academic Press
  • Release : 2021-03-26
  • Pages : 426
  • ISBN : 0128217006
  • Language : En, Es, Fr & De
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Multifunctional Theranostic Nanomedicines in Cancer focuses on new trends, applications, and the significance of novel multifunctional nanotheranostics in cancer imaging for diagnosis and treatment. Cancer nanotechnology offers new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions—including targeting, imaging, and therapy—have been intensively studied with the goal of overcoming the limitations of conventional cancer diagnosis and therapy. Thus theranostic nanomedicines have emerged in recent years to provide an efficient and safer alternative in cancer management. This book covers polymer-based therapies, lipid-based therapies, inorganic particle-based therapies, photo-related therapies, radiotherapies, chemotherapies, and surgeries. Multifunctional Theranostic Nanomedicines in Cancer offers an indispensable guide for researchers in academia, industry, and clinical settings; it is also ideal for postgraduate students; and formulation scientists working on cancer. Provides a comprehensive resource of recent scientific progress and novel applications of theranostic nanomedicines Discusses treatment options from a pharmaceutical sciences perspective Includes translational science and targeted CNS cancer treatment

Multifunctional Theranostic Nanomedicines in Cancer

Multifunctional Theranostic Nanomedicines in Cancer
A Book

by Malay K. Das

  • Publisher : Elsevier
  • Release : 2021-04-09
  • Pages : 426
  • ISBN : 012821712X
  • Language : En, Es, Fr & De
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Multifunctional Theranostic Nanomedicines in Cancer focuses on new trends, applications, and the significance of novel multifunctional nanotheranostics in cancer imaging for diagnosis and treatment. This book is divided into three parts that cover materials, therapies and the targeting of specific cancers. Sections cover polymer-based therapies, lipid-based therapies, inorganic particle-based therapies, photo-related therapies, radiotherapies, chemotherapies and surgeries. This book presents an indispensable guide for researchers in academia, industry and clinical settings, but it is also ideal for postgraduate students and formulation scientists working on cancer. Provides a comprehensive resource of recent scientific progress and novel applications of theranostic nanomedicines Discusses treatment options from a pharmaceutical sciences perspective Includes translational science and targeted CNS cancer treatments

Advances in Nanotheranostics II

Advances in Nanotheranostics II
Cancer Theranostic Nanomedicine

by Zhifei Dai

  • Publisher : Springer
  • Release : 2016-01-11
  • Pages : 381
  • ISBN : 9811000638
  • Language : En, Es, Fr & De
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This book surveys recent advances in theranostics based on magnetic nanoparticles, ultrasound contrast agents, silica nanoparticles and polymeric micelles. It presents magnetic nanoparticles, which offer a robust tool for contrast enhanced MRI imaging, magnetic targeting, controlled drug delivery, molecular imaging guided gene therapy, magnetic hyperthermia, and controlling cell fate. Multifunctional ultrasound contrast agents have great potential in ultrasound molecular imaging, multimodal imaging, drug/gene delivery, and integrated diagnostics and therapeutics. Due to their diversity and multifunctionality, polymeric micelles and silica-based nanocomposites are highly capable of enhancing the efficacy of multimodal imaging and synergistic cancer therapy. This comprehensive book summarizes the main advances in multifunctional nanoprobes for targeted imaging and therapy of gastric cancer, and explores the clinical translational prospects and challenges. Although more research is needed to overcome the substantial obstacles that impede the development and availability of nanotheranostic products, such nontrivial nanoagents are expected to revolutionize medical treatments and help to realize the potential of personalized medicine to diagnose, treat, and follow-up patients with cancer. Zhifei Dai is a Professor at the Department of Biomedical Engineering, College of Engineering, Peking University, China.

Handbook of Nanomaterials for Cancer Theranostics

Handbook of Nanomaterials for Cancer Theranostics
A Book

by Joao Conde

  • Publisher : Elsevier
  • Release : 2018-06-27
  • Pages : 606
  • ISBN : 0128133406
  • Language : En, Es, Fr & De
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Handbook of Nanomaterials for Cancer Theranostics focuses on recent developments in advanced theranostic nanomedicines from a chemical and biological perspective where the advantages of theranostics are achieved by combining multiple components. The authors explore the pros and cons of theranostic nanomaterials developed in cancer research in the last 15 years, with the different strategies compared and scrutinized. In addition, the book explores how nanomaterials may overcome the regulatory hurdles facing theranostic nanomedicines. This is an important research reference for postgraduates and researchers in nanomedicine and cancer research who want to learn more on how nanomaterials can help create more effective cancer treatments. Highlights the development of smart theranostic nanomaterials to tackle biomedical problems in cancer therapy and diagnostics Explores the regulatory hurdles facing theranostic nanomedicine Discusses how the use of nanomaterials can help create more effective cancer treatments

Advanced Theranostic Nanomedicine in Oncology

Advanced Theranostic Nanomedicine in Oncology
A Book

by Gianni Ciofani,Attilio Marino,Christos Tapeinos

  • Publisher : Frontiers Media SA
  • Release : 2020-03-18
  • Pages : 329
  • ISBN : 2889636216
  • Language : En, Es, Fr & De
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Bio-Nanomedicine for Cancer Therapy

Bio-Nanomedicine for Cancer Therapy
A Book

by Flavia Fontana

  • Publisher : Springer Nature
  • Release : 2021
  • Pages : 329
  • ISBN : 3030581748
  • Language : En, Es, Fr & De
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Advances in Nanotheranostics I

Advances in Nanotheranostics I
Design and Fabrication of Theranosic Nanoparticles

by Zhifei Dai

  • Publisher : Springer
  • Release : 2015-12-15
  • Pages : 336
  • ISBN : 3662485443
  • Language : En, Es, Fr & De
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This book highlights the recent advances in nanotheranostics from basic research to potential applications, and discusses the modular design and engineering of multiplex nanoparticles including gold nanostructures, luminescent nanoparticles, dendrimers and liposomes. Each chapter demonstrates multifunctional nanoparticles with topics covering targeting, imaging, delivery, diagnostics, and therapy as new modalities for cancer theranostics. This comprehensive book presents expert views on the latest developments in theranostic nanomedicine. It focuses on potential theranostic applications of multifunctional nanoparticles ranging from identifying noninvasively cancer cells by molecular detection, and visualizing in vivo drug delivery by means of contrast enhanced imaging, to destroying cancer cell s with minimal side effects via selective accumulation at tumor sites, and real-time monitoring therapeutic effectiveness. It also presents an interdisciplinary survey of nanotheranostics and as such is a valuable resource for researchers and students in related fields. Zhifei Dai is a Professor at the Department of Biomedical Engineering, College of Engineering, Peking University, China.

Experimental Biology and Medicine

Experimental Biology and Medicine
A Book

by Anonim

  • Publisher : Unknown Publisher
  • Release : 2009
  • Pages : 329
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Nanotheranostics for Cancer Applications

Nanotheranostics for Cancer Applications
A Book

by Prakash Rai,Stephanie A. Morris

  • Publisher : Springer
  • Release : 2018-11-12
  • Pages : 480
  • ISBN : 3030017753
  • Language : En, Es, Fr & De
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This book is the first to focus specifically on cancer nanotheranostics. Each of the chapters that make up this comprehensive volume is authored by a researcher, clinician, or regulatory agency member known for their expertise in this field. Theranostics, the technology to simultaneously diagnose and treat a disease, is a nascent field that is growing rapidly in this era of personalized medicine. As the need for cost-effective disease diagnosis grows, drug delivery systems that can act as multifunctional carriers for imaging contrast and therapy agents could provide unique breakthroughs in oncology. Nanotechnology has enabled the development of smart theranostic platforms that can concurrently diagnose disease, start primary treatment, monitor response and initiate secondary treatments if required. In oncology, chemotherapeutics have been routinely used. Some drugs have proven effective but all carry risks of adverse side effects. There is growing interest in using remotely triggered drug delivery systems to limit cytotoxicity in the diseased area. This book reviews the use of theranostic nanoparticles for cancer applications over the past decade. First, it briefly discusses the challenges and limitations of conventional cancer treatments, and presents an overview of the use of nanotechnology in treating cancer. These introductory chapters are followed by those exploring cancer diagnosis and a myriad of delivery methods for nanotherapeutics. The book also addresses multifunctional platforms, treatment monitoring, and regulatory considerations. As a whole, the book aims to briefly summarize the development and clinical potential of various nanotheranostics for cancer applications, and to delineate the challenges that must be overcome for successful clinical development and implementation of such cancer theranostics.

Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents

Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents
A Book

by Manju Rawat Singh,Deependra Singh,Nagendra Singh Chauhan,Jagat Kanwar

  • Publisher : Academic Press
  • Release : 2020-03
  • Pages : 320
  • ISBN : 0128196661
  • Language : En, Es, Fr & De
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Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents provides sound data on the utility of biological and plant-based drugs and describes challenges faced in all aspects offering indispensable strategies to use in the development of bioactive medicines. Bioactive based medications are commonly used throughout the world and have been recognized by physicians and patients for their therapeutic efficacy. Bioactive formulations, including their subordinates and analogs, address 50% of all medicines in clinical practice. Novel bioactive medicine transporters can cure many disorders by both spatial and transitory approaches and have various justifications in medicinal potential. This book presents information on the utility of natural, plant, animal and bioengineered bioactive materials. It is a fundamental source of information and data for pharmacognosists, pharmaceutical analysts, drug transport scientists and pharmacologists working in bioactive medications.

Cancer Nanotheranostics: What Have We Learned So Far?

Cancer Nanotheranostics: What Have We Learned So Far?

by João Conde,Pedro Viana Baptista,Jesús M De La Fuente,Furong Tian

  • Publisher : Frontiers Media SA
  • Release : 2016-03-17
  • Pages : 329
  • ISBN : 288919776X
  • Language : En, Es, Fr & De
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After a quarter of century of rapid technological advances, research has revealed the complexity of cancer, a disease intimately related to the dynamic transformation of the genome. However, the full understanding of the molecular onset of this disease is still far from achieved and the search for mechanisms of treatment will follow closely. It is here that Nanotechnology enters the fray offering a wealth of tools to diagnose and treat cancer. In fact, the National Cancer Institute predicts that over the next years, nanotechnology will result in important advances in early detection, molecular imaging, targeted and multifunctional therapeutics, prevention and control of cancer. Nanotechnology offers numerous tools to diagnose and treat cancer, such as new imaging agents, multifunctional devices capable of overcome biological barriers to deliver therapeutic agents directly to cells and tissues involved in cancer growth and metastasis, and devices capable of predicting molecular changes to prevent action against precancerous cells. Nanomaterials-based delivery systems in Theranostics (Diagnostics & Therapy) provide better penetration of therapeutic and diagnostic substances within the body at a reduced risk in comparison to conventional therapies. At the present time, there is a growing need to enhance the capability of theranostics procedures where nanomaterials-based sensors may provide for the simultaneous detection of several gene-associated conditions and nanodevices with the ability to monitor real-time drug action. These innovative multifunctional nanocarriers for cancer theranostics may allow the development of diagnostics systems such as colorimetric and immunoassays, and in therapy approaches through gene therapy, drug delivery and tumor targeting systems in cancer. Some of the thousands and thousands of published nanosystems so far will most likely revolutionize our understanding of biological mechanisms and push forward the clinical practice through their integration in future diagnostics platforms. Nevertheless, despite the significant efforts towards the use of nanomaterials in biologically relevant research, more in vivo studies are needed to assess the applicability of these materials as delivery agents. In fact, only a few went through feasible clinical trials. Nanomaterials have to serve as the norm rather than an exception in the future conventional cancer treatments. Future in vivo work will need to carefully consider the correct choice of chemical modifications to incorporate into the multifunctional nanocarriers to avoid activation off-target, side effects and toxicity. Moreover the majority of studies on nanomaterials do not consider the final application to guide the design of nanomaterial. Instead, the focus is predominantly on engineering materials with specific physical or chemical properties. It is imperative to learn how advances in nanosystem’s capabilities are being used to identify new diagnostic and therapy tools driving the development of personalized medicine in oncology; discover how integrating cancer research and nanotechnology modeling can help patient diagnosis and treatment; recognize how to translate nanotheranostics data into an actionable clinical strategy; discuss with industry leaders how nanotheranostics is evolving and what the impact is on current research efforts; and last but not least, learn what approaches are proving fruitful in turning promising clinical data into treatment realities.

Plant Nanobionics

Plant Nanobionics
Volume 2, Approaches in Nanoparticles, Biosynthesis, and Toxicity

by Ram Prasad

  • Publisher : Springer Nature
  • Release : 2019-09-30
  • Pages : 488
  • ISBN : 3030163792
  • Language : En, Es, Fr & De
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Plant Nanobionics, Volume 2 continues the important discussion of nanotechnology in plants, but focuses with a focus on biosynthesis and toxicity. This book discusses novel approaches to biosynthesis of nanoparticles for the increase of plant production systems, controlled release of agrochemicals and management of plant biotic stress. Green biosynthesis of metallic nanoparticles from bee propolis, artificial photosynthesis and hybrid structures are presented. Although engineered nanoparticles have great potential for solving many agricultural and societal problems, their consequences on the ecosystems and environment must be responsibly considered. This volume aims to contribute to the limited literature on this topic through its comprehensive examination of nanoparticle toxicity on plants, microbes and human health. Environmental risks with recent data are discussed as well as risks associated with the transfer of nanoparticles through the food chain. This volume highlights the study of a mechanistic approach and the study of nanoparticles towards nanobionics. The application of polymeric materials for smart packing in the food industry and agriculture sector as well as the future of nanomaterials in detecting soil microbes for environmental remediation are also included.

Multifunctional Gold Nanostars for Cancer Theranostics

Multifunctional Gold Nanostars for Cancer Theranostics
A Book

by Yang Liu

  • Publisher : Springer
  • Release : 2018-03-28
  • Pages : 71
  • ISBN : 9783319749198
  • Language : En, Es, Fr & De
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This thesis presents the development of theranostic gold nanostars (GNS) for multimodality cancer imaging and therapy. Furthermore, it demonstrates that a novel two-pronged treatment, combining immune-checkpoint inhibition and GNS-mediated photothermal nanotherapy, can not only eradicate primary treated tumors but also trigger immune responses to treat distant untreated tumors in a mouse animal model. Cancer has become a significant threat to human health with more than eight million deaths each year, and novel methods for cancer management to improve patients’ overall survival are urgently needed. The developed multifunctional GNS nanoprobe with tip-enhanced plasmonics in the near-infrared region can be combined with (1) surface-enhanced Raman spectroscopy (SERS), (2) two-photon photoluminescence (TPL), (3) X-ray computed tomography (CT), (4) magnetic resonance imaging (MRI), (5) positron emission tomography (PET), and (6) photothermal therapy (PTT) for cancer imaging and treatment. The ability of the GNS nanoprobe to detect submillimeter intracranial brain tumors was demonstrated using PET scan – a superior non-invasive imaging modality – in a mouse animal model. In addition, delayed rechallenge with repeated cancer cell injection in cured mice did not lead to new tumor formation, indicating generation of a memorized immune response to cancer. The biocompatible gold nanostars with superior capabilities for cancer imaging and treatment have great potential for translational medicine applications.

Nanomedicine

Nanomedicine
Principles and Perspectives

by Yi Ge,Songjun Li,Shenqi Wang,Richard Moore

  • Publisher : Springer
  • Release : 2014-12-01
  • Pages : 413
  • ISBN : 1461421403
  • Language : En, Es, Fr & De
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Increasing demand for and awareness of the applications of nanotechnology in medicine has resulted in the emergence of a new fast-growing multidisciplinary area - nanomedicine. This book offers comprehensive knowledge of and diverse perspectives on nanomedicine through two independent volumes. It aims to bridge the gap between nanotechnology and medicine through contributions by world-renowned experts from wide range of backgrounds including academia, industry, professional consultancy, and government agencies. Each contribution integrates knowledge from a wide range of areas to present the fundamentals of new applications and products of nanomedicine, as well as an outlook for the future. This book can well serve as a reference and guide for students, academics, researchers, scientists, engineers, clinicians, government researchers, and healthcare professionals.

Multifunctional Nanocarriers for Contemporary Healthcare Applications

Multifunctional Nanocarriers for Contemporary Healthcare Applications
A Book

by Barkat, Md. Abul,A.B., Harshita,Beg, Sarwar,Ahmad, Farhan J.

  • Publisher : IGI Global
  • Release : 2018-01-12
  • Pages : 602
  • ISBN : 1522547827
  • Language : En, Es, Fr & De
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Advances in technology permeates every aspect of life, including the healthcare system. Nanotechnology based systems have gained popularity based upon their promise, size, and other characteristics. Multifunctional Nanocarriers for Contemporary Healthcare Applications is a critical academic publication that explores advancements in nanostructured systems, applications of these systems in healthcare, and biomedical applications of these systems. Featuring coverage on a wide range of topics, such as hydrogels, controlled drug delivery systems, and nanomedicine, this book is geared toward researchers, students, and academicians seeking current research on advancements and applications of nanostructured systems in the healthcare industry.

Cancer Nanotheranostics

Cancer Nanotheranostics
Volume 1

by Muthupandian Saravanan,Hamed Barabadi

  • Publisher : Springer
  • Release : 2021-06-30
  • Pages : 365
  • ISBN : 9783030743291
  • Language : En, Es, Fr & De
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Nanotechnology is an interdisciplinary research field that integrates chemistry, engineering, biology, and medicine. Nanomaterials offer tremendous opportunity as well as challenges for researchers. Of course, cancer is one of the world's most common health problems, responsible for many deaths. Exploring efficient anticancer drugs could revolutionize treatment options and help manage cancer mortality. Nanomedicine plays a significant role in developing alternative and more effective treatment strategies for cancer theranostics. This book mainly focuses on the emerging trends using nanomaterials and nanocomposites as alternative anticancer material’s. The book is divided into three main topic areas: how to overcome existing traditional approaches to combat cancer, applying multiple mechanisms to target the cancer cells, and how nanomaterials can be used as effective carriers. The contents highlight recent advances in interdisciplinary research on processing, morphology, structure, and properties of nanostructured materials and their applications to combat cancer.Cancer Nanotheranostics is comprehensive in that it discusses all aspects of cancer nanotechnology. Because of the vast amount of information, it was decided to split this material into two volumes. In the first volume of Cancer Nanotheranostics, we discuss the role of different nanomaterials for cancer therapy, including lipid-based nanomaterials, protein and peptide-based nanomaterials, polymer-based nanomaterials, metal-organic nanomaterials, porphyrin-based nanomaterials, metal-based nanomaterials, silica-based nanomaterials, exosome-based nanomaterials and nano-antibodies. In the second volume, we discuss the nano-based diagnosis of cancer, nano-oncology for clinical applications, nano-immunotherapy, nano-based photothermal cancer therapy, nano-erythrosomes for cancer drug delivery, regulatory perspectives of nanomaterials, limitations of cancer nanotheranostics, the safety of nano-biomaterials for cancer nanotheranostics, multifunctional nanomaterials for targeting cancer nanotheranostics, and the role of artificial intelligence in cancer nanotheranostics.

Introduction to Nanotheranostics

Introduction to Nanotheranostics
A Book

by Subramanian Tamil Selvan,Karthikeyan Narayanan

  • Publisher : Springer
  • Release : 2016-06-15
  • Pages : 79
  • ISBN : 9811010080
  • Language : En, Es, Fr & De
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This book offers readers an introduction to the current status of nanoparticles and other nanomaterials that have potential applications in theranostics. Above all, it highlights the diagnostic and therapeutic applications of metallic (e.g. Au, Ag), semiconducting quantum dots (e.g. CdSe, CdTe), magnetic (e.g. Fe3O4, FePt, Co), and multifunctional (combination of two or three) nanoparticles.

Handbook of Materials for Nanomedicine

Handbook of Materials for Nanomedicine
Metal-Based and Other Nanomaterials

by Vladimir Torchilin

  • Publisher : CRC Press
  • Release : 2020-05-15
  • Pages : 538
  • ISBN : 1000067130
  • Language : En, Es, Fr & De
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In the fast-developing field of nanomedicine, a broad variety of materials have been used for the development of advanced delivery systems for drugs, genes, and diagnostic agents. With the recent breakthroughs in the field, we are witnessing a new age of disease management, which is governed by precise regulation of dosage and delivery. This book presents the advances in the use of lipid-based and inorganic nanomaterials for medical imaging, diagnosis, theranostics, and drug delivery. The materials discussed include liposome-scaffold systems, elastic liposomes, targeted liposomes, solid lipid nanoparticles, lipoproteins, exosomes, porous inorganic nanomaterials, silica nanoparticles, and inorganic nanohybrids. The book provides all available information about them and describes in detail their advantages and disadvantages and the areas where they could be utilized successfully.

Gastric Cancer Prewarning and Early Diagnosis System

Gastric Cancer Prewarning and Early Diagnosis System
A Book

by Daxiang Cui

  • Publisher : Springer
  • Release : 2017-06-21
  • Pages : 355
  • ISBN : 9402409513
  • Language : En, Es, Fr & De
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The book explores recent developments in the application of nanotechnology in the early detection of gastric cancer. It discusses various aspects, such as screening for gastric cancer-associated biomarkers; establishing new ultrasensitive detection methods based on nanoparticle labeling and nanoeffects; developing a new generation of nanodevices for high-throughput examination of serum and breath biomarkers; developing multifunctional nanoprobes for targeted imaging and simultaneous therapy of gastric cancer; evaluating the biosafety of multifunctional nanoprobes; and the establishment of a pre-warning and early diagnosis system. It also presents clinical applications and prospects. The book provides a valuable reference for researchers in nanomedicine and clinicians involved in gastric cancer and radiology.

Pulmonary Nanomedicine

Pulmonary Nanomedicine
Diagnostics, Imaging, and Therapeutics

by Neeraj Vij

  • Publisher : CRC Press
  • Release : 2012-08-06
  • Pages : 300
  • ISBN : 9814364142
  • Language : En, Es, Fr & De
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This book explores engineered nanomaterials (ENM) pulmonary effects and familiarizes readers with unique aspects of nanomaterial application and research. Focusing on the diagnostic and therapeutic utilities of nanomaterials in different lung diseases, it discusses the novel applications of nanotechnology for the treatment of airway diseases such as asthma, allergy, chronic obstructive pulmonary diseases, cystic fibrosis, and lung cancer. In an attempt to synchronize the efforts of pulmonary biologists, chemists, and clinicians in developing novel nano-based tools for airway diseases, the book also discusses the strategies to overcome the pathophysiological and technical barriers.