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Multifunctional Theranostic Nanomedicines in Cancer

Multifunctional Theranostic Nanomedicines in Cancer
A Book

by Malay K. Das

  • Publisher : Academic Press
  • Release : 2021-03-26
  • Pages : 426
  • ISBN : 0128217006
  • Language : En, Es, Fr & De
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Multifunctional Theranostic Nanomedicines in Cancer focuses on new trends, applications, and the significance of novel multifunctional nanotheranostics in cancer imaging for diagnosis and treatment. Cancer nanotechnology offers new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions—including targeting, imaging, and therapy—have been intensively studied with the goal of overcoming the limitations of conventional cancer diagnosis and therapy. Thus theranostic nanomedicines have emerged in recent years to provide an efficient and safer alternative in cancer management. This book covers polymer-based therapies, lipid-based therapies, inorganic particle-based therapies, photo-related therapies, radiotherapies, chemotherapies, and surgeries. Multifunctional Theranostic Nanomedicines in Cancer offers an indispensable guide for researchers in academia, industry, and clinical settings; it is also ideal for postgraduate students; and formulation scientists working on cancer. Provides a comprehensive resource of recent scientific progress and novel applications of theranostic nanomedicines Discusses treatment options from a pharmaceutical sciences perspective Includes translational science and targeted CNS cancer treatment

Handbook of Nanomaterials for Cancer Theranostics

Handbook of Nanomaterials for Cancer Theranostics
A Book

by Joao Conde

  • Publisher : Elsevier
  • Release : 2018-06-27
  • Pages : 606
  • ISBN : 0128133406
  • Language : En, Es, Fr & De
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Handbook of Nanomaterials for Cancer Theranostics focuses on recent developments in advanced theranostic nanomedicines from a chemical and biological perspective where the advantages of theranostics are achieved by combining multiple components. The authors explore the pros and cons of theranostic nanomaterials developed in cancer research in the last 15 years, with the different strategies compared and scrutinized. In addition, the book explores how nanomaterials may overcome the regulatory hurdles facing theranostic nanomedicines. This is an important research reference for postgraduates and researchers in nanomedicine and cancer research who want to learn more on how nanomaterials can help create more effective cancer treatments. Highlights the development of smart theranostic nanomaterials to tackle biomedical problems in cancer therapy and diagnostics Explores the regulatory hurdles facing theranostic nanomedicine Discusses how the use of nanomaterials can help create more effective cancer treatments

Advances in Nanotheranostics II

Advances in Nanotheranostics II
Cancer Theranostic Nanomedicine

by Zhifei Dai

  • Publisher : Springer
  • Release : 2016-01-11
  • Pages : 381
  • ISBN : 9811000638
  • Language : En, Es, Fr & De
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This book surveys recent advances in theranostics based on magnetic nanoparticles, ultrasound contrast agents, silica nanoparticles and polymeric micelles. It presents magnetic nanoparticles, which offer a robust tool for contrast enhanced MRI imaging, magnetic targeting, controlled drug delivery, molecular imaging guided gene therapy, magnetic hyperthermia, and controlling cell fate. Multifunctional ultrasound contrast agents have great potential in ultrasound molecular imaging, multimodal imaging, drug/gene delivery, and integrated diagnostics and therapeutics. Due to their diversity and multifunctionality, polymeric micelles and silica-based nanocomposites are highly capable of enhancing the efficacy of multimodal imaging and synergistic cancer therapy. This comprehensive book summarizes the main advances in multifunctional nanoprobes for targeted imaging and therapy of gastric cancer, and explores the clinical translational prospects and challenges. Although more research is needed to overcome the substantial obstacles that impede the development and availability of nanotheranostic products, such nontrivial nanoagents are expected to revolutionize medical treatments and help to realize the potential of personalized medicine to diagnose, treat, and follow-up patients with cancer. Zhifei Dai is a Professor at the Department of Biomedical Engineering, College of Engineering, Peking University, China.

Advances in Nanotheranostics I

Advances in Nanotheranostics I
Design and Fabrication of Theranosic Nanoparticles

by Zhifei Dai

  • Publisher : Springer
  • Release : 2015-12-15
  • Pages : 336
  • ISBN : 3662485443
  • Language : En, Es, Fr & De
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This book highlights the recent advances in nanotheranostics from basic research to potential applications, and discusses the modular design and engineering of multiplex nanoparticles including gold nanostructures, luminescent nanoparticles, dendrimers and liposomes. Each chapter demonstrates multifunctional nanoparticles with topics covering targeting, imaging, delivery, diagnostics, and therapy as new modalities for cancer theranostics. This comprehensive book presents expert views on the latest developments in theranostic nanomedicine. It focuses on potential theranostic applications of multifunctional nanoparticles ranging from identifying noninvasively cancer cells by molecular detection, and visualizing in vivo drug delivery by means of contrast enhanced imaging, to destroying cancer cell s with minimal side effects via selective accumulation at tumor sites, and real-time monitoring therapeutic effectiveness. It also presents an interdisciplinary survey of nanotheranostics and as such is a valuable resource for researchers and students in related fields. Zhifei Dai is a Professor at the Department of Biomedical Engineering, College of Engineering, Peking University, China.

Engineering of Multifunctional Nanomaterials for Cancer Theranostics

Engineering of Multifunctional Nanomaterials for Cancer Theranostics
A Book

by Shreya Goel

  • Publisher : Unknown Publisher
  • Release : 2017
  • Pages : 190
  • ISBN : 9876543210XXX
  • Language : En, Es, Fr & De
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Development of novel imaging probes for cancer diagnosis is critical for early disease detection and management. The past two decades have witnessed a surge in the development and evolution of radiolabeled nanoparticles as a new frontier in personalized cancer nanomedicine. The dynamic synergism of positron emission tomography (PET) and nanotechnology combines the sensitivity and quantitative nature of PET with the multifunctionality and tunability of nanomaterials, which can help overcome certain key challenges in the field. Silica, "generally recognized as safe" (GRAS) by the Food and Drug Administration (FDA) of the United States, has emerged as one of the leading nanomaterials employed for molecular imaging and therapy of a wide variety of diseases, including cancer. However in vivo biodistribution and active targeting of silica-based nanomaterials has remained a relatively under explored area, based mainly on semi-quantitative techniques such as fluorescence imaging. In this dissertation, I explore the concept of radiolabeled silica nanoparticles for vasculature-targeted imaging of different tumor types. Both chelator-based and chelator-free radiolabeling techniques were employed for accurate and quantitative analysis of the in vivo pharmacokinetics of radiolabeled silica nanomaterials. (Chapters 2 and 3) The large surface area, ease of tunability and facile silica chemistry were employed to create multifunctional silica-based materials to simultaneously seek-and-treat cancers, by incorporating multiple components into a single nanoplatform. Photodynamic agent, porphyrin was loaded into the central cavity of hollow mesoporous silica nanoparticles, and the shell was decorated with photothermal nanoparticles, CuS, yielding a multimodal theranostic nanoplatform which could synergistically annihilate the tumor without relapse. (Chapter 4) A major hurdle in the successful clinical translation of nanomaterials is their rapid sequestration by the organs of the reticuloendothelial system (RES), mainly liver and spleen, and prolonged retention in the body, raising long-term toxicity concerns. To combat this issue, two approaches were employed; (i) Synthesis of biodegradable mesoporous silica nanoparticles (Chapter 5), and (ii) development of ultrasmall nanoparticles including renal clearable Au nanoparticles and hepatically cleared ultrasmall mesoporous silica nanoparticles (Chapter 6); for prolonged blood circulation, enhanced tumor uptake and rapid clearance from the body, enabling unprecedented tumor-to-normal tissue contrast. Overall, the reported studies explore the synergism of molecular imaging and therapy, and nanotechnology. While the application of nanomaterials in the former imparts multifunctionality to the molecular agent, allowing multimodal imaging and synergistic therapeutic regimes to be carried out simultaneously; molecular imaging techniques such as PET, allow accurate measurement of the in vivo pharmacokinetics of the nanomaterials, playing a major role towards their successful clinical translation. Further work will be required to better understand the in vivo biodistribution of both biodegradable and ultrasmall nanomaterials, and further employ them for early and specific detection of cancer, effective treatment and monitoring.

Multifunctional Gold Nanostars for Cancer Theranostics

Multifunctional Gold Nanostars for Cancer Theranostics
A Book

by Yang Liu

  • Publisher : Springer
  • Release : 2018-03-15
  • Pages : 71
  • ISBN : 331974920X
  • Language : En, Es, Fr & De
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This thesis presents the development of theranostic gold nanostars (GNS) for multimodality cancer imaging and therapy. Furthermore, it demonstrates that a novel two-pronged treatment, combining immune-checkpoint inhibition and GNS-mediated photothermal nanotherapy, can not only eradicate primary treated tumors but also trigger immune responses to treat distant untreated tumors in a mouse animal model. Cancer has become a significant threat to human health with more than eight million deaths each year, and novel methods for cancer management to improve patients’ overall survival are urgently needed. The developed multifunctional GNS nanoprobe with tip-enhanced plasmonics in the near-infrared region can be combined with (1) surface-enhanced Raman spectroscopy (SERS), (2) two-photon photoluminescence (TPL), (3) X-ray computed tomography (CT), (4) magnetic resonance imaging (MRI), (5) positron emission tomography (PET), and (6) photothermal therapy (PTT) for cancer imaging and treatment. The ability of the GNS nanoprobe to detect submillimeter intracranial brain tumors was demonstrated using PET scan – a superior non-invasive imaging modality – in a mouse animal model. In addition, delayed rechallenge with repeated cancer cell injection in cured mice did not lead to new tumor formation, indicating generation of a memorized immune response to cancer. The biocompatible gold nanostars with superior capabilities for cancer imaging and treatment have great potential for translational medicine applications.

Nanotheranostics for Cancer Applications

Nanotheranostics for Cancer Applications
A Book

by Prakash Rai,Stephanie A. Morris

  • Publisher : Springer
  • Release : 2018-11-12
  • Pages : 480
  • ISBN : 3030017753
  • Language : En, Es, Fr & De
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This book is the first to focus specifically on cancer nanotheranostics. Each of the chapters that make up this comprehensive volume is authored by a researcher, clinician, or regulatory agency member known for their expertise in this field. Theranostics, the technology to simultaneously diagnose and treat a disease, is a nascent field that is growing rapidly in this era of personalized medicine. As the need for cost-effective disease diagnosis grows, drug delivery systems that can act as multifunctional carriers for imaging contrast and therapy agents could provide unique breakthroughs in oncology. Nanotechnology has enabled the development of smart theranostic platforms that can concurrently diagnose disease, start primary treatment, monitor response and initiate secondary treatments if required. In oncology, chemotherapeutics have been routinely used. Some drugs have proven effective but all carry risks of adverse side effects. There is growing interest in using remotely triggered drug delivery systems to limit cytotoxicity in the diseased area. This book reviews the use of theranostic nanoparticles for cancer applications over the past decade. First, it briefly discusses the challenges and limitations of conventional cancer treatments, and presents an overview of the use of nanotechnology in treating cancer. These introductory chapters are followed by those exploring cancer diagnosis and a myriad of delivery methods for nanotherapeutics. The book also addresses multifunctional platforms, treatment monitoring, and regulatory considerations. As a whole, the book aims to briefly summarize the development and clinical potential of various nanotheranostics for cancer applications, and to delineate the challenges that must be overcome for successful clinical development and implementation of such cancer theranostics.

Advanced Theranostic Nanomedicine in Oncology

Advanced Theranostic Nanomedicine in Oncology
A Book

by Gianni Ciofani,Attilio Marino,Christos Tapeinos

  • Publisher : Frontiers Media SA
  • Release : 2020-03-18
  • Pages : 329
  • ISBN : 2889636216
  • Language : En, Es, Fr & De
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Bio-Nanomedicine for Cancer Therapy

Bio-Nanomedicine for Cancer Therapy
A Book

by Flavia Fontana

  • Publisher : Springer Nature
  • Release : 2021
  • Pages : 329
  • ISBN : 3030581748
  • Language : En, Es, Fr & De
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Frontiers in Anti-Cancer Drug Discovery: Volume 11

Frontiers in Anti-Cancer Drug Discovery: Volume 11
A Book

by Atta-ur-Rahman ,Muhammad Iqbal Choudhary

  • Publisher : Bentham Science Publishers
  • Release : 2020-09-01
  • Pages : 163
  • ISBN : 9811422125
  • Language : En, Es, Fr & De
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Frontiers in Anti-Cancer Drug Discovery is a book series devoted to publishing the latest advances in anti-cancer drug design and discovery. In each volume, eminent scientists contribute reviews relevant to all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series should prove to be of interest to all pharmaceutical scientists involved in research in anti-cancer drug design and discovery. The book series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field. The eleventh volume of the series focuses on reviews on targeted therapies and drug delivery systems. This volume covers the following topics: - PI3K/Akt/mTOR Pathway in Acute Lymphoblastic Leukemia Targeted Therapies - Polymeric Nanomedicines in Treatment of Breast Cancer: Review of Contemporary Research - Treatment of Lung Cancer in the New Era - Oral Administration of Cancer Chemotherapeutics Exploiting Self-Nanoemulsifying Drug Delivery System: Recent Progress and Application - Targeting Approaches for the Diagnosis and Treatment of Cancer.

Multifunctional Nanoparticles for Drug Delivery Applications

Multifunctional Nanoparticles for Drug Delivery Applications
Imaging, Targeting, and Delivery

by Sonke Svenson,Robert K. Prud'homme

  • Publisher : Springer Science & Business Media
  • Release : 2012-02-22
  • Pages : 374
  • ISBN : 146142304X
  • Language : En, Es, Fr & De
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This book presents the medical challenges that can be reduced or even overcome by recent advances in nanoscale drug delivery. Each chapter highlights recent progress in the design and engineering of select multifunctional nanoparticles.

Cancer Theranostics

Cancer Theranostics
A Book

by Xiaoyuan Chen,Stephen Wong

  • Publisher : Academic Press
  • Release : 2014-03-20
  • Pages : 544
  • ISBN : 0124078842
  • Language : En, Es, Fr & De
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Aiding researchers seeking to eliminate multi-step procedures, reduce delays in treatment and ease patient care, Cancer Theranostics reviews, assesses, and makes pertinent clinical recommendations on the integration of comprehensive in vitro diagnostics, in vivo molecular imaging, and individualized treatments towards the personalization of cancer treatment. Cancer Theranostics describes the identification of novel biomarkers to advance molecular diagnostics of cancer. The book encompasses new molecular imaging probes and techniques for early detection of cancer, and describes molecular imaging-guided cancer therapy. Discussion also includes nanoplatforms incorporating both cancer imaging and therapeutic components, as well as clinical translation and future perspectives. Supports elimination of multi-step approaches and reduces delays in treatments through combinatorial diagnosis and therapy Fully assesses cancer theranostics across the emergent field, with discussion of biomarkers, molecular imaging, imaging guided therapy, nanotechnology, and personalized medicine Content bridges laboratory, clinic, and biotechnology industries to advance biomedical science and improve patient management

Biomaterials for Cancer Therapeutics

Biomaterials for Cancer Therapeutics
Diagnosis, Prevention and Therapy

by Kinam Park

  • Publisher : Elsevier
  • Release : 2013-11-23
  • Pages : 530
  • ISBN : 0857096761
  • Language : En, Es, Fr & De
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Cancer can affect people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is now being developed to target, treat and prevent cancer. This unique book discusses the role and potential of biomaterials in treating this prevalent disease. The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Chapters in part two discuss synthetic vaccines, proteins and polymers for cancer therapeutics. Part three focusses on theranosis and drug delivery systems, whilst the final set of chapters look at biomaterial therapies and cancer cell interaction. This extensive book provides a complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer. Biomaterials for cancer therapeutics is an essential text for academics, scientists and researchers within the biomedical industry, and will also be of interest to clinicians with a research interest in cancer therapies and biomaterials. A complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer Discusses the fundamentals of biomaterials for cancer therapeutics Discusses synthetic vaccines, proteins and polymers for cancer therapeutics

Cancer Nanotheranostics

Cancer Nanotheranostics
Volume 1

by Muthupandian Saravanan,Hamed Barabadi

  • Publisher : Springer
  • Release : 2021-06-30
  • Pages : 365
  • ISBN : 9783030743291
  • Language : En, Es, Fr & De
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Nanotechnology is an interdisciplinary research field that integrates chemistry, engineering, biology, and medicine. Nanomaterials offer tremendous opportunity as well as challenges for researchers. Of course, cancer is one of the world's most common health problems, responsible for many deaths. Exploring efficient anticancer drugs could revolutionize treatment options and help manage cancer mortality. Nanomedicine plays a significant role in developing alternative and more effective treatment strategies for cancer theranostics. This book mainly focuses on the emerging trends using nanomaterials and nanocomposites as alternative anticancer material’s. The book is divided into three main topic areas: how to overcome existing traditional approaches to combat cancer, applying multiple mechanisms to target the cancer cells, and how nanomaterials can be used as effective carriers. The contents highlight recent advances in interdisciplinary research on processing, morphology, structure, and properties of nanostructured materials and their applications to combat cancer.Cancer Nanotheranostics is comprehensive in that it discusses all aspects of cancer nanotechnology. Because of the vast amount of information, it was decided to split this material into two volumes. In the first volume of Cancer Nanotheranostics, we discuss the role of different nanomaterials for cancer therapy, including lipid-based nanomaterials, protein and peptide-based nanomaterials, polymer-based nanomaterials, metal-organic nanomaterials, porphyrin-based nanomaterials, metal-based nanomaterials, silica-based nanomaterials, exosome-based nanomaterials and nano-antibodies. In the second volume, we discuss the nano-based diagnosis of cancer, nano-oncology for clinical applications, nano-immunotherapy, nano-based photothermal cancer therapy, nano-erythrosomes for cancer drug delivery, regulatory perspectives of nanomaterials, limitations of cancer nanotheranostics, the safety of nano-biomaterials for cancer nanotheranostics, multifunctional nanomaterials for targeting cancer nanotheranostics, and the role of artificial intelligence in cancer nanotheranostics.

Cancer Nanotheranostics: What Have We Learned So Far?

Cancer Nanotheranostics: What Have We Learned So Far?

by João Conde,Pedro Viana Baptista,Jesús M De La Fuente,Furong Tian

  • Publisher : Frontiers Media SA
  • Release : 2016-03-17
  • Pages : 329
  • ISBN : 288919776X
  • Language : En, Es, Fr & De
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After a quarter of century of rapid technological advances, research has revealed the complexity of cancer, a disease intimately related to the dynamic transformation of the genome. However, the full understanding of the molecular onset of this disease is still far from achieved and the search for mechanisms of treatment will follow closely. It is here that Nanotechnology enters the fray offering a wealth of tools to diagnose and treat cancer. In fact, the National Cancer Institute predicts that over the next years, nanotechnology will result in important advances in early detection, molecular imaging, targeted and multifunctional therapeutics, prevention and control of cancer. Nanotechnology offers numerous tools to diagnose and treat cancer, such as new imaging agents, multifunctional devices capable of overcome biological barriers to deliver therapeutic agents directly to cells and tissues involved in cancer growth and metastasis, and devices capable of predicting molecular changes to prevent action against precancerous cells. Nanomaterials-based delivery systems in Theranostics (Diagnostics & Therapy) provide better penetration of therapeutic and diagnostic substances within the body at a reduced risk in comparison to conventional therapies. At the present time, there is a growing need to enhance the capability of theranostics procedures where nanomaterials-based sensors may provide for the simultaneous detection of several gene-associated conditions and nanodevices with the ability to monitor real-time drug action. These innovative multifunctional nanocarriers for cancer theranostics may allow the development of diagnostics systems such as colorimetric and immunoassays, and in therapy approaches through gene therapy, drug delivery and tumor targeting systems in cancer. Some of the thousands and thousands of published nanosystems so far will most likely revolutionize our understanding of biological mechanisms and push forward the clinical practice through their integration in future diagnostics platforms. Nevertheless, despite the significant efforts towards the use of nanomaterials in biologically relevant research, more in vivo studies are needed to assess the applicability of these materials as delivery agents. In fact, only a few went through feasible clinical trials. Nanomaterials have to serve as the norm rather than an exception in the future conventional cancer treatments. Future in vivo work will need to carefully consider the correct choice of chemical modifications to incorporate into the multifunctional nanocarriers to avoid activation off-target, side effects and toxicity. Moreover the majority of studies on nanomaterials do not consider the final application to guide the design of nanomaterial. Instead, the focus is predominantly on engineering materials with specific physical or chemical properties. It is imperative to learn how advances in nanosystem’s capabilities are being used to identify new diagnostic and therapy tools driving the development of personalized medicine in oncology; discover how integrating cancer research and nanotechnology modeling can help patient diagnosis and treatment; recognize how to translate nanotheranostics data into an actionable clinical strategy; discuss with industry leaders how nanotheranostics is evolving and what the impact is on current research efforts; and last but not least, learn what approaches are proving fruitful in turning promising clinical data into treatment realities.

Advances in Cancer Nanotheranostics for Experimental and Personalized Medicine

Advances in Cancer Nanotheranostics for Experimental and Personalized Medicine
A Book

by Yusuf Tutar

  • Publisher : Bentham Science Publishers
  • Release : 2020-06-08
  • Pages : 198
  • ISBN : 9811456895
  • Language : En, Es, Fr & De
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Nanotheranostics is a recent medical field which integrates diagnostic imaging protocols and therapeutic functions to monitor real time drug release in the body and distribution to the target site. The combined processes allow technicians to observe the effectiveness of a specifically designed drug candidate and predict its possible side effects. All these features help clinicians in optimizing treatment options for cancer and other diseases for the individual patient. Current research is tailored to individual therapy because each drug may display a variety of responses depending on variations in an individual’s genetics and subsequently, their clinical biochemistry. Many tumors are still challenging for therapists in terms of available treatment and nanotheranostic strategies may help them to combat cancer more efficiently. Advances in Cancer Nanotheranostics for Experimental and Personalized Medicine presents information about current theranostic technologies in use at clinics and recent research on nanotheranostic applications, with a focus on cancer treatment. Information is presented in seven organized chapters that cover the basics of cancer nanotheranostics, tumor microenvironmental factors, gene therapy and gene delivery concepts, and the combined application of diagnostic imaging with cancer chemotherapy. A chapter focusing on the role of non-coding MRNAs in breast cancer carcinogenesis is also included, giving readers a glimpse of the complexities in the molecular biology of cancer which drive the need for new theranostic technologies. The book is of interest to medical professionals (including oncologists and specialists in internal medicine), diagnostic imaging technicians, and researchers in the fields of pharmacology, molecular biology and nuclear medicine.

Nano-Oncologicals

Nano-Oncologicals
New Targeting and Delivery Approaches

by Maria José Alonso,Marcos Garcia-Fuentes

  • Publisher : Springer
  • Release : 2014-10-15
  • Pages : 473
  • ISBN : 3319080849
  • Language : En, Es, Fr & De
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This authoritative volume focuses on emerging technologies in cancer nano medicine, characterized by their multi-functionality and potential to address simultaneously diverse issues of clinical relevance in the treatment of cancer. The book consists of sixteen chapters divided into six sections: 1) Biological Barriers in Cancer; 2) Tumor Targeting; 3) Targeting the Immune System; 4) Gene Therapy; 5) Nano theranostics and 6) Translational Aspects of Nano-Oncologicals. The volume starts with an introduction describing the biological barriers associated with cancer therapy and highlighting ways to overcome such barriers through the use of nanotechnology. This is followed by an analysis of the two major targeting strategies currently under investigation in cancer therapy: namely, the targeting of cancer cells and the targeting of the immune system. In the first case, the book presents liposomal and polymer-based therapies, including photodynamic approaches. In the second case, it analyzes in detail the possibility of either improving the efficiency of the immune system toward preventing cancer progression (cancer immunomodulation) or generating responses against specific cancer antigens (cancer vaccines). Beyond these targeting options, Nano-Oncologicals: New Targeting and Delivery Approaches presents the most recent technological advances in the area of nucleic acid-based therapies, along with those in the area of theranostics, where the design of multifunctional nano carriers becomes vital. Following the study of the most promising nanotechnologies around the development of nano-oncologicals, the book ends with an overview of regulatory and toxicological issues, which are critical in their translational pathway, and the presentation of a nucleic acid-based therapy case-study. This book is an important resource for scientists interested in the design and development of anticancer nanotechnologies and also to those aiming to push their technology through clinical development.

Light-Responsive Nanostructured Systems for Applications in Nanomedicine

Light-Responsive Nanostructured Systems for Applications in Nanomedicine
A Book

by Salvatore Sortino

  • Publisher : Springer
  • Release : 2015-11-20
  • Pages : 263
  • ISBN : 3319229427
  • Language : En, Es, Fr & De
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The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. Review articles for the individual volumes are invited by the volume editors. Readership: research chemists at universities or in industry, graduate students.

Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering

Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering
A Book

by Ashutosh Tiwari,Atul Tiwari

  • Publisher : John Wiley & Sons
  • Release : 2013-02-19
  • Pages : 576
  • ISBN : 1118644743
  • Language : En, Es, Fr & De
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This groundbreaking, multidisciplinary work is one of the first books to cover Nanotheragnostics, the new developmental edge of nanomedicine. Through a collection of authoritative chapters, the book reports on nanoscopic therapeutic systems that incorporate therapeutic agents, molecular targeting, and diagnostic imaging capabilities. An invaluable reference for researchers in materials science, bioengineering, pharmacy, biotechnology, and nanotechnology, this volume features four main parts on biomedical nanomaterials, advanced nanomedicine, nanotheragnostics, and nanoscaffolds technology.

Nanomedicines for Breast Cancer Theranostics

Nanomedicines for Breast Cancer Theranostics
A Book

by Nanasaheb D. Thorat,Joanna Bauer

  • Publisher : Elsevier
  • Release : 2020-03-08
  • Pages : 438
  • ISBN : 0128200170
  • Language : En, Es, Fr & De
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Nanomedicines for Breast Cancer Theranostics addresses the translational aspects and clinical perspectives of breast cancer nanomedicine from a multidisciplinary perspective. The book summarizes research efforts at the preclinical and clinical stage of nanostructures and nanomedicine for dealing with the important challenge of nanomedicine translation in breast cancer theranostics. This book is an important resource for those working in both academia and industry, focusing on hot topics in biomaterials, biomedical engineering, drug delivery and oncology. Shows how the discovery of new nanomedicines is leading directly to an increase in the early-stage diagnosis of breast cancer Includes coverage of breast cancer nanomedicine standardization and characterization, highlighting newly developed treatments, diagnostics and treatment monitoring tools Explains why the design of nanobiomaterials make them effective drug carriers when treating breast cancer